GenomeNet

Database: Pfam
Entry: DUF2569
LinkDB: DUF2569
Original site: DUF2569 
#=GF ID   DUF2569
#=GF AC   PF10754.6
#=GF DE   Protein of unknown function (DUF2569)
#=GF AU   Mistry J, Coggill P
#=GF SE   PRODOM_PD088965
#=GF GA   25.00 25.00;
#=GF TC   26.00 26.00;
#=GF NC   24.20 24.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR019690;
#=GF CC   This family is conserved in bacteria. The function is not known,
#=GF CC   but several members are annotated as being YdgK or a homologue
#=GF CC   thereof.
#=GF SQ   87
#=GS A5G5I4_GEOUR/56-202      AC A5G5I4.1
#=GS Q32FE7_SHIDS/1-114       AC Q32FE7.1
#=GS F3Z3T1_DESAF/111-247     AC F3Z3T1.1
#=GS I2B6C0_SHIBC/26-163      AC I2B6C0.1
#=GS A0A068QVJ6_9ENTR/7-143   AC A0A068QVJ6.1
#=GS A0A0C5WLT0_9GAMM/6-154   AC A0A0C5WLT0.1
#=GS D4Z3B0_SPHJU/114-255     AC D4Z3B0.1
#=GS H2IP55_RAHAC/7-145       AC H2IP55.1
#=GS A0A0A7RYD0_9GAMM/7-154   AC A0A0A7RYD0.1
#=GS E8TLF4_MESCW/37-177      AC E8TLF4.1
#=GS H1Y7K8_9SPHI/693-834     AC H1Y7K8.1
#=GS W0LEY4_9ENTR/6-144       AC W0LEY4.1
#=GS U3TVW0_9ENTR/4-87        AC U3TVW0.1
#=GS J7TAJ0_MORMO/30-168      AC J7TAJ0.1
#=GS R7KRR8_9BURK/45-170      AC R7KRR8.1
#=GS F2JYH3_MARM1/7-157       AC F2JYH3.1
#=GS I0DNQ7_PROSM/7-143       AC I0DNQ7.1
#=GS E1SCI3_PANVC/7-145       AC E1SCI3.1
#=GS B2VER3_ERWT9/6-144       AC B2VER3.1
#=GS K8W6J7_9ENTR/7-143       AC K8W6J7.1
#=GS Q6F8W8_ACIAD/7-157       AC Q6F8W8.1
#=GS A0A0A1B341_9ENTR/7-145   AC A0A0A1B341.1
#=GS C5BDE4_EDWI9/3-141       AC C5BDE4.1
#=GS Q7CQK6_SALTY/6-144       AC Q7CQK6.1
#=GS K8WHF5_PRORE/7-143       AC K8WHF5.1
#=GS Q82TA5_NITEU/137-287     AC Q82TA5.1
#=GS B4EVZ4_PROMH/16-152      AC B4EVZ4.1
#=GS Q6D8N4_PECAS/25-162      AC Q6D8N4.1
#=GS G9Z7Z2_9ENTR/6-144       AC G9Z7Z2.1
#=GS Q13WP8_BURXL/9-159       AC Q13WP8.1
#=GS K8WWE0_PRORE/23-169      AC K8WWE0.1
#=GS A6T9X3_KLEP7/6-144       AC A6T9X3.1
#=GS A0A089MH51_9BACL/20-170  AC A0A089MH51.1
#=GS E6WB72_PANSA/27-166      AC E6WB72.1
#=GS R5AH29_9CLOT/14-134      AC R5AH29.1
#=GS D4GDR7_PANAM/7-145       AC D4GDR7.1
#=GS G0J545_CYCMS/677-811     AC G0J545.1
#=GS K8WIU6_PRORE/27-173      AC K8WIU6.1
#=GS U3TUB8_9ENTR/7-95        AC U3TUB8.1
#=GS A0A0A0Z5H2_9ENTR/7-145   AC A0A0A0Z5H2.1
#=GS K8WXK6_9ENTR/23-169      AC K8WXK6.1
#=GS C0ZKJ8_BREBN/37-186      AC C0ZKJ8.1
#=GS A0A0D5VD38_9BURK/9-159   AC A0A0D5VD38.1
#=GS C6VXZ1_DYAFD/689-834     AC C6VXZ1.1
#=GS A8AH07_CITK8/6-144       AC A8AH07.1
#=GS Q11PB3_CYTH3/18-166      AC Q11PB3.1
#=GS D8MRM5_ERWBE/6-144       AC D8MRM5.1
#=GS H8KQW8_SOLCM/696-837     AC H8KQW8.1
#=GS A0A0A2UB44_9BACL/17-167  AC A0A0A2UB44.1
#=GS A0A089PMX8_PLUGE/6-144   AC A0A089PMX8.1
#=GS A0A077DJ58_9BURK/30-174  AC A0A077DJ58.1
#=GS D2THL0_CITRI/6-144       AC D2THL0.1
#=GS C7PJY5_CHIPD/686-834     AC C7PJY5.1
#=GS I0DTQ0_PROSM/17-163      AC I0DTQ0.1
#=GS E6WEB6_PANSA/7-145       AC E6WEB6.1
#=GS H2INW9_RAHAC/26-168      AC H2INW9.1
#=GS A0A0D5ZCB9_PAEPS/8-137   AC A0A0D5ZCB9.1
#=GS D3VGE3_XENNA/7-143       AC D3VGE3.1
#=GS R6FCA3_9BACE/68-194      AC R6FCA3.1
#=GS A0A0A6ZTE3_SHIDY/1-114   AC A0A0A6ZTE3.1
#=GS D5BKN6_ZUNPS/695-839     AC D5BKN6.1
#=GS W8U4L9_YEREN/7-145       AC W8U4L9.1
#=GS H2INX0_RAHAC/21-163      AC H2INX0.1
#=GS A0A097R2G5_HAFAL/10-148  AC A0A097R2G5.1
#=GS Q2KYB8_BORA1/88-235      AC Q2KYB8.1
#=GS R4YQT5_OLEAN/8-158       AC R4YQT5.1
#=GS YDGK_ECOLI/6-144         AC P76180.2
#=GS I0DTQ2_PROSM/37-129      AC I0DTQ2.1
#=GS Q7N4G2_PHOLL/7-143       AC Q7N4G2.1
#=GS F6IPU9_9SPHN/130-268     AC F6IPU9.1
#=GS I2BA02_SHIBC/6-144       AC I2BA02.1
#=GS A4W9X1_ENT38/6-144       AC A4W9X1.1
#=GS A0A075R999_BRELA/1-86    AC A0A075R999.1
#=GS A4WB81_ENT38/32-171      AC A4WB81.1
#=GS F5LH74_9BACL/26-171      AC F5LH74.1
#=GS A7MG59_CROS8/26-163      AC A7MG59.1
#=GS Q7CIK4_YERPE/7-145       AC Q7CIK4.1
#=GS W0J8A5_9BACT/459-515     AC W0J8A5.1
#=GS A8GE03_SERP5/6-144       AC A8GE03.1
#=GS A0A089UEN6_9ENTR/6-144   AC A0A089UEN6.1
#=GS D3V192_XENBS/7-143       AC D3V192.1
#=GS A0A089NYT5_9BACL/17-167  AC A0A089NYT5.1
#=GS Q129A1_POLSJ/41-186      AC Q129A1.1
#=GS C6XYQ2_PEDHD/701-850     AC C6XYQ2.1
#=GS D2TK55_CITRI/27-166      AC D2TK55.1
#=GS A7MMM1_CROS8/6-144       AC A7MMM1.1
#=GS W0HY46_9ENTR/8-137       AC W0HY46.1
A5G5I4_GEOUR/56-202                 .........................................PTGVGGWLKLLVVGMLVlgplmGAGRIENDFMMAEHq.npNITSLNEWKTFKNA--......--------TWWTFYIVAAMSFYG....GWGLARGRDVSv..........vnRAKAI..LWLTGPVASINL-....AIIIPFI..iFg...ktEAGNPQFIG..GFFASVVGAIIWTVYLSKSKRVRNTYC............
Q32FE7_SHIDS/1-114                  ........................................m-----------------.....---------LLYTA....ALSSPQTFQTLGAQAL......TTQILWGVSFITAIAMWYYTLWL....TIAFFKRRRCV.............PKHYI..IWLLISVLLAVK-....AFAFSPV...-......--EDSIAVR..QLLFTLLATALIVPYFKRSSRVKATFV............
F3Z3T1_DESAF/111-247                ......................................kvk---FGGLLYLFSIFIFF.....PPFGAFANLIHIN-....-EI-KANWSAVLTN--......---ADLIIFYVPAFAYLFLTLYI....VFLYYRRDKGL.............SSWWI..GSWSVLLAADALG....ALYLDRH..gI.....pNHLFQTQIE..SLAGRLFWVGLWSIYLLCSKRVKHTFV............
I2B6C0_SHIBC/26-163                 ........................................l-SKINGLLYFPALGLIL.....GVIRIAIELYSFTI....AAFNY------FNETG......FLSYYAMGVFVLLICGFIVSIYA....AWLFFRRKKGT.............RKAMI..AYYVTGLIIALYL....TVLPAII...F.....dVQQDSDNII..LLMSGVFGVVIWIPYFIFSKRINMVFC............
A0A068QVJ6_9ENTR/7-143              ........................................y-YRINGWLLAPAAYLIM.....TLIAASLMLLLYMM....TFI--HKNETIHQISG......GFTTLWYTSVLTTAIMWCFTVWV....LKLLFIRSKRF.............PRIFI..IWLMISVLIAVK-....TFAFSPI...-......--SDEMAIR..SLLWPLLAAAAFVPYIKRSHRVKMTFT............
A0A0C5WLT0_9GAMM/6-154              ........................................v-KGLSGWLAVIALGVLV.....SPIRLLGELFKF-S....SLIKEGNVGYLAAEASpg.yieWYRELIYCEIFVNLFSLTVCIYM....VYLFFSKSKHF.............PKIYI..FMAFFTPIMQSVD....AYAVKSI..mS.....pIILPDELTK..GIFLSLITIVIWVPYMLMSKRVKNTFV............
D4Z3B0_SPHJU/114-255                qfglygvmasllvgialnvpvrtleflgsipalgsysppwf-----------------.....--------------....----------------......--VGLYSVMLADVVILSSLYMFA....FAMALRLAPLF.............PRFLV..MVWGIDLLAQISI....AHLVAGI..dNvphgvdAALLNMLTG..NVKKVLISAAIWLPYLLLSDRVNLTF-r...........
H2IP55_RAHAC/7-145                  .........................................YKRIGGWLLAPMAYLIV.....TLLSVVLMLFLFSM....ALFVPESREYLFTNSQ......AFTLQWYFSVVTTLAMGVFTVAV....LWQFCKRARAL.............PKMYI..IWLLCTVLLAVK-....AFAFSPV...-......--TDDLAVR..NLLLPLLAAAVFVPYFKRSLRVKETFT............
A0A0A7RYD0_9GAMM/7-154              ........................................l-EGIKGWLIIPAIEIII.....SIPSLCFYILTMII....SANKLGILSDLFSSRTsf.ysiYTLIFSISQILCMGILTFFYFYL....AYLFFSKDYRT.............PKWYI..VVQLFDIIISIIF....YILFVFG...L......SLFSYSNES..EIIISLVCSVIWIVYFLTSVRVKNTFI............
E8TLF4_MESCW/37-177                 ......................................lvg---FGGWLMLLAIGQAL.....SPLPTLAELGASSD....GY---NQLMLVPNG--......--PMVVYGEVALLLAFMVFQLVV....LVAMLRRSLRF.............KQLFL..IQWLAIPVAVILD....AIWVSTAi.gVs...vrKVVTGEALA..TYIVSFVLIGLWVAYVYKSVRVRNTFT............
H1Y7K8_9SPHI/693-834                ........................................g-RPIGGWLYLIVLGLSV.....AAIKISVSLVSG--....YYLKLSLWNTYQTGTKs....iLFKALLFFETGGNVLTICYAIFC....LILILKKRDIL.............PRYIT..GLYIFNLAFIVID....AVFAY-S...F......YGEDNLVMS..DILKAVLAAAIWVPYFRMSTRVKETFI............
W0LEY4_9ENTR/6-144                  .........................................YSRIGGWLLAPMAYLIV.....TLLSASLMLLLYGM....AIFMPESREYLTTNAQ......AFTLPWYLSVLTALVMWGFTLYL....LWLFCQRSQRF.............PKLFL..VWLLITVLLAIK-....AFAFAPV...-......--PDEMAVR..SLGWPLLMAALLVPYIKRSQRVKGTFT............
U3TVW0_9ENTR/4-87                   ...........vfthrrrgvavqhlgvldllsaiapsatsl-----------------.....--------------....----------------......-----------------------....-----------.............----H..LWLLITVLLALK-....TFAFTPV...-......--ADGKAIQ..TLLLALLSAAVFVPYFKRSQRVKQAFI............
J7TAJ0_MORMO/30-168                 ........................................m-SRIGGWLWLPLITLFL.....SLGAGGYTLSEWYD....-LY--QQNAGY-IPDR......VLQVMYI-NIAFTILTMLLILTT....LYYFFRLSRYL.............PKLFI..AFILFAIASEAIQ....EIVLVNL...L.....dVNVDFTLYY..PLIRLVIYAIIWISYFLVSERVKRTFV............
R7KRR8_9BURK/45-170                 .........................................PHGVHGWLLVFVATVIL.....SIILTAIDAINAVN....-VM--NQAGALNW---......-------AVLSPSIVIIGLYIYC....LWLIARKREAY.............VVKQT..IVILWVVGPISL-....MFLTLLF...-......--GASVDNA..TVVRSCLYAALWTLYFLFSKRVACTY-g...........
F2JYH3_MARM1/7-157                  ........................................i-KGLGGWLILVGFGVLI.....SPIRLLVTLIPTYK....PIFEDGAWEALTTVGSev.ytpYFGSLLVGEIAFNTIMVVASIYL....IYLFFSKHYLF.............PKLYI..GIIAASLIFIPLD....AWIVTKV...Fp...gePMFDPETTK..EFMRSFMIGVIWVPYMLVSKRVHATFV............
I0DNQ7_PROSM/7-143                  ........................................h-HRITGWLLAPAAFILL.....TCFAVCSMVVMYFI....TLY--RIITTIDDWTH......YIPFDWYLSFLITIVMMVFTIHI....LKLMFMRSRHF.............PRRFI..IWMLVLLLLGLK-....TFYFANI...-......--DSLTALK..TLAWPLIGAAIFVPYIKNSARVKMTFT............
E1SCI3_PANVC/7-145                  .......................................ap--RIGGWLLLPLAWLIM.....TLLTTVLVLAMYLT....PLFNPEWRVALFSHGS......TLLSYWAISLLTAVAVWAYSLWI....SWLFFKRSRRL.............PRHYL..LWLLITVLLALK-....TFAFTPV...-......--ADSRALQ..TLLLSLLAAAIFAPYFKRSKRVKTTFI............
B2VER3_ERWT9/6-144                  ........................................q-TRLGGWLLVPLAWLIM.....TLLTSALVMAMYFS....ALFDPAMRHALFTPPH......GALVQWAASLLTSAVVWGYSAWV....TWIFCKRSRRL.............PRHYI..IWLLLSVILAIK-....TFAFSPV...-......--TDAAAIR..MLLIALLAASVLVPYFRRSQRVKATFI............
K8W6J7_9ENTR/7-143                  .........................................YHRITGWLLAPAAFMLL.....TFFATCAMVVMYVT....KLY--QIMTTIDDWHN......FIPLDWWLSFLITVVMTFFTAHI....LKLMFFRSRHF.............PRRFI..IWLMILLLLGLK-....TFAFAAV...-......--DDDTALK..ALAWPLLGAGIFVPYIKRSERVKMTFT............
Q6F8W8_ACIAD/7-157                  ........................................l-KGLGGWLTLVGFGLIV.....SPIRLIVTGYQTYY....PMFSEGIFNSLTSVDSvy.yhpLWIYYILGEITVNTIFVLTSFVL....LYLFFKKHYLF.............PKVFI..SVCIAMIIFILID....ASLIKLIl.pN.....eEIFDSDTAS..ELMRSIFYGMIWIPYMMFSKRVKVNFV............
A0A0A1B341_9ENTR/7-145              .......................................ap--RLGGWLLLPLAWLIL.....TVLTSALVVVMYIG....ALFNPAWRDALFSHDT......AFLTQWGLSLATSLAVWLYSAWV....TWIFCQRSRRL.............PRHYI..IWLLLTVALALK-....TFAFSPI...-......--ADGAAVR..SLLLALLAAATLVPYFRRSQRVKKTFI............
C5BDE4_EDWI9/3-141                  ........................................t-DRIGGWLFAPLAYMIL.....SLVSSSLMLALFVM....TLLQHGGSGRLWAHGG......TFSSQWGLSLLITLGVWCFSLHV....LRLFFKRSRRF.............PKHFI..AWLLVMLLLALK-....SFAFSPI...-......--SDTLALR..GIVTPLLAAAVFVPYIKRSARVRQTFI............
Q7CQK6_SALTY/6-144                  .........................................PQRIGGWLLGPLAWLLV.....ALLSASLALLLYVM....ALATPQTFKTLSGQET......GNLLLWGISFITAIAMWYYTLWL....TIAFFKRRRCV.............PKHYI..IWLLVSVLLAVK-....AFAFSPV...-......--SDAFAVR..QLLFPLLATALIVPYLKRSARVKTTFV............
K8WHF5_PRORE/7-143                  ........................................a-NRITGWLLVPAIYLLL.....TFLAVCSMTVMYCI....KFY--EIVTTVDHWTS......FIPAAWYLSFAITIGMTIFSIHV....LQLMFSRSKHF.............PRRFI..IWLMILLLLGIK-....TFAFSPI...-......--DDETALQ..VLAWPLIGAGFFVPYLKRSQRVKMTFT............
Q82TA5_NITEU/137-287                ........................................l-EGLGGWLILVGSNVVL.....SPFVIAARTYKSYA....EMFASGVWDVLTSPDSma.yhaLWAPLAIGEIILNSALILAWIYI....AFLFFSKRRAF.............PFWFI..AIHIATVCLIVID....AIVVHHIl.pD.....aPIFDANTLR..ELSRPIGAILIWAPYMLMSKRVKSTF-l...........
B4EVZ4_PROMH/16-152                 .......................................ka--PITGWLLAPLAYLLL.....SIVGLGLMSVLYLI....RYF--SDFSIIHQLPF......HVVSSWYLSVLTTWAMFAFTAYL....LRQFFYRAKNF.............PRLFI..IWLLINLLLAIK-....SFGFAPV...-......--DDQTAVK..SLLWAVMATVCFVPYIKYAKRVRETFT............
Q6D8N4_PECAS/25-162                 ........................................q-QKINGILYLPALGIIL.....SVITTPFSLYDIIN....AMIIHFKNTGF-----......-LGYYALALVFFLLAMFALEIFA....AMSFFRRKKRT.............RNVMV..AYYLVSAVLVGYM....TLLPAYL...F.....eVKLDTGDIR..AIVSSVFGIAVWIPYFLFSKRIPLVF-s...........
G9Z7Z2_9ENTR/6-144                  ........................................a-ERIGGWLLAPLAWLLV.....ALLSASLAVVLYAS....ALASPQTFTLLRAQSA......GHIGLWVLSCLFAIAMWYYTLWL....TIAFFKRRALV.............PKHYI..IWLLISVLLAVK-....AFAFSPI...-......--PDAMALR..QLVFPLLATALLVPYFKRSARVKRTFV............
Q13WP8_BURXL/9-159                  .......................................sl--RIRGWLLLALTCLAA.....WVLHTALTMRDPLK....LMLEWELLAVFVRREThg.wyrAVIAMVGCDVVTGAFIVAGAGWL....ALLAWRRSARF.............VAQVQ..AWLVAIVVMRTG-....AYLLGDY..mTh...aiGIDIAVPYD..GVMQAVVAAALGIPYFRSSRRVHETFI............
K8WWE0_PRORE/23-169                 ........................................l-TGIGGWLILPMLGIVL.....SLIILPFSIYEQ--....NVQVIEYWIELTDPQSss.fipLFKELIYFEVLGNVILYATLLFL....SYVFFTKKKLT.............IKIYI..FFQIFSLVLTVTD....IILASIL...L.....dLEVESSDIK..DIFRALIACAIWIPYFLVSRRVKNTFV............
A6T9X3_KLEP7/6-144                  ........................................a-ERIGGWLLAPLAWLLV.....ALLSASLSLLFFAN....ALMSPQTYTLLRAMSA......GHMALWVASLLFALAMWYYTLWL....TIAFFKRRSVV.............PKHYI..IWLLITLLLAIK-....AFAFSPV...-......--SDVLALR..QLLFPLLGAALLAPYFRRSQRVKRTFV............
A0A089MH51_9BACL/20-170             .........................................PSGLGGWLVLVQIGLIA.....TLFLVALQLLNYNL....PSFNPEYWDILTSKEGel.yhpLWAPLIIFEAASNVLLLLLCVFT....LVLFYQKKALL.............PRMII..LLYCINLLISVID....YTLSLNIp.lI.....nEMGGVNGIR..DLLRSLFTCIIWVAYFRKSERVANTFV............
E6WB72_PANSA/27-166                 ........................................f-RKIGGVLFLPLIGLIV.....TAASYLFSMTDAFK....VMT--ENYSHLNAN--......-AKTFFILSLAIYIGQFLFTVTV....LSFFLKKKKIL.............PTFYI..FFLISVVATMSLN....VYLLYMLi.pN......VKIGYNELV..PVFRNVITALIWIPYFMTSVRVKRTFI............
R5AH29_9CLOT/14-134                 ........................................w-NGVGGWLLVFAIVLGL.....NTVPLFIQAFMILS....ILFSTHNGL-------......-----LLLTCLVDFVYLGLLLAS....LILLLRHRIAF.............RWCYA..AVVALNVCLFVW-....-IL-STG...-......----SRQ-M..NACLPLLGQVAWLAYLFCSERVRIT--c...........
D4GDR7_PANAM/7-145                  .......................................ap--RIGGWLLVPLAWLLM.....TLLTTALVMAMYLT....PLFDTQWRATLFNHSS......LVTTYWAISLFTATALWAYSMWV....VWIFFKRSSRL.............PRHYI..VWLLITVLLALK-....TFAFTPV...-......--SDARAIQ..TLLLSLAAAAIFVPYFKRSARVKATFT............
G0J545_CYCMS/677-811                ........................................n-KNIGGWLVLPAIGIIL.....TPIQITMNFFSV--....GYLDEAIWLQAINL--......ELTESLAFELIFNILLIVFSVLL....IILFYTRRTST.............PKLMI..LFYVVNLAAILID....TVMTEDN...-......---ISLENR..ALIQAFVGAAIWIPYFFFSERVKSTFC............
K8WIU6_PRORE/27-173                 ........................................l-HGISGWLILPIIGLFY.....MLYKTVMMLLQEIS....QVQ--TAWPLATQADSdfyipgFATGFYLLQLGYGVLIALFLWTF....IAAVKWKKQAK.............WLFII..TMVLFTLMVLVA-....RFVFPYI...F.....gLEINHSNII..TAINGSFYCVLWIPYFLVSHRVKNTFI............
U3TUB8_9ENTR/7-95                   ........................................p-PRIAGWLLLPLAWLIM.....TMLTSALVVALYLR....PLFDTELRNTLFSHAS......ILMTQWLVSLLTAAAVWLYSIWV....CWIFYQRSRRL.............PRHYI..S------------....-------...-......---------..---------------------------gc..........
A0A0A0Z5H2_9ENTR/7-145              .......................................sp--RIGGWLLLPLAWLIM.....TMLTSALVVALYLR....PLFDSELRTTLFSHAN......LLLSQWLVSLLTAAAVWLYSIWV....CWIFCRRSRRL.............PRHYT..IWLLMTVVLALK-....TFAFTPV...-......--ADGKALQ..TLLLTLLAAALFVPYFKRSRRVKQTFT............
K8WXK6_9ENTR/23-169                 ........................................l-QGISGWLILPVIGLFY.....MFYQLVMMSLTDIH....QVQ--IVWPLATNTDSyfyvpmFEGAFYSLQVGYGVLAALLIWTL....IAALLWQRKAK.............VLFIA..TMLLYTLIAVTS-....HFIFPYL...F.....nMEIIYSHIS..EVIGAVIYCFIWGPYFGFSERVKQTFI............
C0ZKJ8_BREBN/37-186                 .........................................PKGLGGWLIWPTIMVVL.....SPFSVLASIIGIFQ...dHAEAMEGLQPFMEQSL......LFTLYYYGNILLEIGLLAFSLTL....LVFYFQKKKRA.............PHLFV..GLILFYLILNMIDl..lAWASFDS..lFg...dtSQLVKQSGL..RLLQTGITAMIWIPYFRLSIRVKNTFV............
A0A0D5VD38_9BURK/9-159              .........................................PRRIGGCLLIALICLAA.....WACSTAFALRDPLK....LMLEWELLAVFVRPEThg.wyrTVIAMVGCDVIIGLFIVAGAGWL....ALLVRRRSARF.............PGQVQ..AWLLAIVVMRTV-....AYLLGDH..mTh...aiSIAIAIPFD..GFVQAVAAAALGIPYFRLSRRVRQTFV............
C6VXZ1_DYAFD/689-834                .......................................sk----NGWLIL--IGIVI.....VALSVLLPLGLMTAe.agSFFTIAEWDRMNDATGlk..rfGYQLFLILQCIFSVGSWCYAIFL....WRLYAKNRDSF.............PIIYS..GFISLNLAFSIL-....SVVLNYC...F.....sIPQEANAFA..GIPFQILWTAALTTYMNKSEAVRRTFV............
A8AH07_CITK8/6-144                  ........................................a-QRIGGWLLGPLAWLLV.....ALLSASLALLLYAT....ALATPQTFHMLSEQST......GNLLLWGVSFITAIAMWYYTLWL....TIAFFKRRHCV.............PKHYI..IWLLVSVLLAIK-....AFAFSPV...-......--SDAFAVR..QLLFPLLAAALIVPYFKRSARVKATFV............
Q11PB3_CYTH3/18-166                 .........................................YNKIGGWMIIPVIGLFI.....TPLRLTVSLFKDLI....PAVTGPDIALYEDPASel.ytpALRYLLYGEIFVNVGFSIFAIVI....LVHLFKFKSIT.............PLLYI..TFVVSNLVFVVAD....SLIVLQL..gL......GTTGDFFDK..ELFQAIVSCSIWIPFFLLSERVKGTFV............
D8MRM5_ERWBE/6-144                  ........................................p-PRIAGLLLVPLAWLIM.....TMLTSAVVVAMYLS....ALLTPELRSALFNNTH......AFTLQWSISLLTSLVVWAYSIWV....TWIFCKRSRRL.............PRHYI..IWLLITVLLAIK-....TFAFSPV...-......--SDAAAIR..TLLIALLAAAVLVPYFKRSQRVKTTFI............
H8KQW8_SOLCM/696-837                .......................................il--PIGGWLILVAIGLCI.....SPLLIFATLTTG--....GFFSEALWANLFNLKP......VVSVMVILEYAINIGFIVFSVLL....IIMFFKRRNTV.............PKLMV..IFYSVYAVWFTSD....MLLASWV..nN......TPVSYQVGK..EIFLVILRVAIFIPYFILSSRVKQTFV............
A0A0A2UB44_9BACL/17-167             ........................................v-SGLGGWLILIQIGLFL.....TIILLAIQLFQYSL....PAVTTESWELLTSDQSdy.yhpLWGPVIIFETVYNALFLMFSIYT....VIAFYRKKSIF.............PRLMI..MFYSVSLVVGIID....YLLLLQI..pMa....rELEDGSSVR..DIVKSVLTCAIWIPYFIKSERVHNTFV............
A0A089PMX8_PLUGE/6-144              ........................................a-ERIGGWLLAPLAWLIV.....AAISASLAVLLYAG....VIISPGALGRLGALSS......TGKGLWLLSLLVAAGMWYYTLWL....TVAFFKRRRLV.............PKHYI..LWLLISVLLAVK-....TFAFSPV...-......--PDSLALR..QLVFPLIAASLLVPYFKRSARVQRTFV............
A0A077DJ58_9BURK/30-174             .......................................vc--GVHGYLLVFTGLMFV.....ESLYLLFSIYEIINi..yTFFYPEVSHTFG----......---FEAYANTVVNIGIIALVIHIgaigVIIWLRRPSAV.............KLLYW..MIWIAGPVASIS-....VYLSGNH..tLi...vpEQIETIQWQ..MLSISLSFAIAFTLYLSYSQRVKNTY-r...........
D2THL0_CITRI/6-144                  ........................................a-QRIGGWLLGPLAWLLL.....ALLSASLALFLYAT....TIATPQTFRMLSAQSA......DNLALWGVSFLTAIAMWYYTLWL....TIAFFKRRRCV.............PKHYI..IWLLVSVLLAVK-....SFAFSPV...-......--PDALAVR..QLLFPLLAAALLVPYFKRAARVKTTFV............
C7PJY5_CHIPD/686-834                .........................................PSAINGFLVVVAVCIFI.....MPVKTFYELINM--....DIFSNNIWLQLDKLTNathstsLLQLLLVTELAGVICILVFNLLL....VSLFLKKRDTF.............PKALV..AFIIFYLVFNLAD....ILAFNYV..yE.....kKDWADASIQ..IIMQACIAAAILIPYMLTSRQVKETFI............
I0DTQ0_PROSM/17-163                 ........................................l-QGIRGWLILPMLGLFY.....MLYQTIIMMYLD--....ILQVKSAWHLVTNEQSdfyvdgFSNAFYMLQMAQGILIVLLAWNV....IAAFKGLKIAK.............PLFII..SMLFYTVMVVVS-....RFVFPNI...F.....gIEIEYSYII..NVVNSCFYCFIWIPYVLMSDRVKQTFI............
E6WEB6_PANSA/7-145                  ........................................p-PRIAGWLLLPLAWLIM.....TMLTSALVVAMYLS....PLFNPELRTTLFSHGG......LLLTQWSISLLTAGLVWVYSIWV....CWIFCKRSRRL.............PRHYI..LWLLMTVLLAMK-....TFAFTPV...-......--SDSKAIQ..TLLLSLLAAAVFVPYFKRSRRVKQTFI............
H2INW9_RAHAC/26-168                 .........................................YSRLGGGLIIIALNLML.....EIIFKAISLITL--....PLY--GINSLIFEE-K......IRVVKFLIFCVMDFLIIGFAIYA....LVFLIRKCERF.............KRVFK..IFIVILISSSFFE....-VILINMeeiFl...ygYIPWTFFFD..SASYPIVLACLAYPYLKCSKRVRMT--lv..........
A0A0D5ZCB9_PAEPS/8-137              ........................................m-SGIKGWLLFFVIYSFY.....LLISNLIDLYFEFY...iYMLVGTI---------......GWNLARTISVGIYLFSEVLIIVS....LVLILKKKRKG.............PNIII..QIEIITIIFGFL-....NFILTIN...-......---KIDELP..SLISTIIFGSIWILYFKNSKRVKATF-e...........
D3VGE3_XENNA/7-143                  ........................................y-YRINGWLLAPAAYLIM.....TLIAASLMLVLYAM...mFIYKNQAIHQF---DD......SFTLMWYLSVLTTTMMWCFTVWV....LRLLFIRSKRF.............PRIFI..IWLMVSVLIAIK-....TFAFSPI...-......--TDEMAIR..SLLWPLLAAAIFVPYIQRSHRVKMTFT............
R6FCA3_9BACE/68-194                 ............ndnihgwlgfllfsiglgglvsalypilt-----------------.....--------------....----Y-NIEEY-----......GSHFLALADVFLGIMLLALAIYT....IYAFLQRKPNA.............VYLAK..VYIAAVFISNVI-....TLFSGE-...F......EESGMGSMP..RLIRSLIWSIVWFLYLTTSKQVNN---i...........
A0A0A6ZTE3_SHIDY/1-114              ........................................m-----------------.....---------LLYTA....ALSSPQTFQTLGAQAL......TTQILWGVSFITAIAMWYYTLWL....TIAFFKRRRCV.............PKHYI..IWLLISVLLAVK-....AFAFSPV...-......--EDSIAVR..QLLFTLLATALIVPYFKRSSRVKATFV............
D5BKN6_ZUNPS/695-839                ........................................h-RPIGGWLVLIAIGLCI.....SPILSFFPMISN--....DYFTSNYFSLWSTGNE......ALVLLVFFEVIFNAASIAFNILI....LIIFFKRRSIA.............PRLII..AFYAFNLIGLSID....ALAASTIp.sIq....sITATADIYS..EVLKSLISCLIWIPYFIYSERVKDTFV............
W8U4L9_YEREN/7-145                  .........................................YQRVGGWLLAPLAYLIV.....TLLSASLMLALYAM....AIFTPESREYLVTNSQ......AFTLQWYFSVVTTALMWIYTIWV....IWLLCSRSQRF.............PQWFI..LWLLLTVLLALK-....AFAFSPI...-......--SDDIALR..TLGWPLLAAAVFVPYIKRSQRVKATFI............
H2INX0_RAHAC/21-163                 ........................................l-TGIGGWLIVVVLHLSS.....MLVFNASLFIEFIYdlniPITDGSDVKLI-----......----PLVLNSFVDVIVFLMAAFS....LNALFRKKYQF.............RKYYR..LFILSCLLHPLLF....ASLCFWYqniT......MYSIPWKIIglMFLYPLGMIFICLPYLDESKRVRLT--lv..........
A0A097R2G5_HAFAL/10-148             ........................................t-KRIGGWLVAPLAYMIV.....SLLSSSLMLIIFLM....TIIQPASRSQLLSHSP......TFSSQWMLSFAITVIIWAFTLFN....LYLFGKRSRRF.............PKFFI..LWLLVMVLLALK-....SFAFSPV...-......--TDAAALR..NMVMPLLAAAIFVPYIKRSSRVRDTFI............
Q2KYB8_BORA1/88-235                 .........................................PKGVGGWLLLFIIVLMLfsplrNIASTAIELNEAEKq.ypELLSIAKWSTYKIT--......--------MWCIVLTSVALNLFA....GQRLRKHHAPDsvtlaikalwfsgPFCQI..LVALAGIFILEV-....-SIPTYL...-......---DTGAMG..PFLSSILGAILWTAYLKKSRRVRNTYF............
R4YQT5_OLEAN/8-158                  ........................................l-NGLSGWLILVAIGIVL.....TPIRIVALVLPMYA....DIFTDGTWDVLTTLGSdv.yspFWAPILIAEVVINIGVMGLWLYI....AFIFFSKKVIF.............PKVYI..GALLFSIAFIAID....AFAMTLVl.pD.....ePIFDPETMK..ELFRSLISAIIWIPYMLKSKRVKATFT............
YDGK_ECOLI/6-144                    .........................................PQRIGGWLLGPLAWLLV.....ALLSTTLALLLYTA....ALSSPQTFQTLGGQAL......TTQILWGVSFITAIALWYYTLWL....TIAFFKRRRCV.............PKHYI..IWLLISVLLAVK-....AFAFSPV...-......--EDGIAVR..QLLFTLLATALIVPYFKRSSRVKATFV............
I0DTQ2_PROSM/37-129                 .......................................pv--GFGGWLLIPMLGLFL.....TLIITPYTLLKDLP....EQL--EGLEKMTDPTSls.fipMAREFIYFNLLSSALIYGLLLFV....CYLFIYKKKLA.............IKVII..LFL----------....-------...-......---------..---------------------------r...........
Q7N4G2_PHOLL/7-143                  .........................................YHRINGWVLAPAAYLIM.....TFLSASVMLALYIM....TFFSQNNMLSA--GNN......HFTLMWFLSVAITAVMWCFTLWV....LKLLFIRSKKF.............PHIFI..IWLIVTVLIALK-....TFAFSPI...-......--PDQMALR..ALAWPLLAAAIFVPYIKRSHRVKMTFT............
F6IPU9_9SPHN/130-268                .......................................pt-----GFMASLIAGMLL.....NVPFRTTEFMLAMP....AM--PASAPTWATT--......----MVGMMTLDVVTLNFFYTIC....FVMALRTAPLF.............PRMLV..FTWLLDVIMQLQI....AEKVTQT..gNlpatvaTALHSLLSG..NIEKVLISAAIWLPYLILSERVNVTF-r...........
I2BA02_SHIBC/6-144                  .........................................PARIGGWLLAPLAWLLM.....TLISTTLINIFYTR....ALFSAHSHQLLADQPA......GQVMLWYLSLACAYAMWGYTLWL....TVAFFKRRRTV.............PRHYI..IWLLITVLLAVK-....SFAFAPV...-......--TDELAVR..QLLFPLLAAAVLAPYFRHSARVKQTFT............
A4W9X1_ENT38/6-144                  ........................................g-EKIGGWLFAPLAWLLV.....ALLSASLALLLYST....ALVTPYALKNLTSQST......MNIAMWFISFGFAIAMWYYTLWL....TIAFFKRRQKV.............PKHYI..IWLLISVLLALK-....AFAFSPV...-......--SDGLAVR..QLLFPLLAASLFAPYFRRSARVKKTFV............
A0A075R999_BRELA/1-86               .....................................mgiv-----------------.....--------------....----------------......-----SFFNIVNTVGILLFVLLV....GIMFFRKKTDT.............PKNIY..VEVLFLVFLIGFD....VYMFL--...-......--NDQTAIK..PLVVSLLTIAA----------------clqvakltkslr
A4WB81_ENT38/32-171                 .........................................YRKIGGLLFLPFLNMLL.....ISYSYFTSMAFTLK....ASIDTLGYLSLPQ---......--STYLFICAGLNFIVLLYIIYV....ASLFLRKKKEL.............PLAYS..VLLVAGIVIMLIDrgigRYLFPQI...-......-ALDFNQIM..PIVTHTIYACIWIPYFRYSVRAKKTFI............
F5LH74_9BACL/26-171                 .......................................is--GFGGWLIVFSIGLIL.....TFISAVYSLVDYLW....PMYESGEAAAYFSDYP......ALGTAILVETVSHLFYAVVPVVL....GYLCYKRKRLF.............KTMSI..IFLLVSLALSGLA....YLAYSFV..sEa....aPDFMDGALR..DLIKTGITCVIWTLYFIKSERVRNTYT............
A7MG59_CROS8/26-163                 ........................................a-SKINGLLYLPAAGLIF.....SLIFLPVEFFDLIS....A------ISAYFSRSG......IITWYAAGAVVLLVALIGITAYA....SWHFFQRKRHT.............PRAMV..IYYLAGVVSALWF....AVLPVSL...F.....gASWDNSSIR..SVLSAFIGVTCWLPYFLKSRRIAQVFV............
Q7CIK4_YERPE/7-145                  .........................................YQRIGGWLLAPLAYLIV.....TLLSASLMLVLYAM....AITTPASREYLVTNTQ......AFTLQWYFSVVTTLVMWLYTLWI....IWLFCSRSRRF.............PKLFI..LWLLLTVLLALK-....AFAFSPI...-......--SDEIALK..TLGWPLLAAAIFVPYIKRSQRVKHTFT............
W0J8A5_9BACT/459-515                ......................................gam-----------------.....--------------....----------------......-----------------------....-----------.............-----..--TIITVVDVLAS...rYWITIP-...-......VEEKAKQIG..QVWGAVVTTCIWVPYMYMSQQVKETFT............
A8GE03_SERP5/6-144                  .........................................YTRIGGWLLAPMAYLIV.....TLLSASLMLLLYGM....AIFVPESREYLLTNAQ......AFSMQWYFSVLTTLAMWCFTLWL....LWLFCHRSQRF.............PKLFL..LWLLITVLLAVK-....AFAFAPV...-......--PDELAVR..SLGWPLLMAALLVPYMKRSKRVKGTFT............
A0A089UEN6_9ENTR/6-144              ........................................p-PRIAGWLLAPLAWLLM.....SLLSSSVALLSFLM....MILSPAAREALGNADA......KTTLLFSLSVGCAMAMWAYTLWL....TIAFFKRRQNV.............VRHYI..LWLLFTVLLAIK-....SFAFSPV...-......--SDKVAVQ..LLLPSLLAAALLVPYLKRSKRVKQTFI............
D3V192_XENBS/7-143                  ........................................y-YRINGWLLAPAAYLIM.....TLIAASLMLLLYLI....TLI--YRNEAIHQVDG......NFTTMWYISVLTTAMMWCFTLWV....LKLLFIHSKRF.............PRIFI..IWLMVSVLIAIK-....TFAFSPI...-......--SDEMAIR..SLLWPLLAAAVFVPYIKRSHRVKMTFT............
A0A089NYT5_9BACL/17-167             ........................................i-SGLGGWLILVQIGLYG.....TIIIQLMQLFQDSF....TAFDADIWTAFTSKGSdf.yhpLWGFIIVFETTFNIAILAFSVYI....LINFYRKKAFL.............PRLLI..IFYIAIPVVGIID....VVLLYQI..pLa....rELGNGDSLK..RIIRSAFTCAIWTAYLLKSERVHNTFV............
Q129A1_POLSJ/41-186                 ........................................p-GGVGGWLALLIAGLIFlgplfSAGRISSDFMDTESk.ypKLLTVEAWLNYKNT--......--------AWIFFGIATLFGIYA....GWCLARRRIST............sPFIAIaaIWILGPLLSVIL-....AIILPII..fFg....aTGLDAAGAG..ALAVSGLPAVAWTLYLLKSKRVKALY-h...........
C6XYQ2_PEDHD/701-850                ........................................a-RPIGGWLVLLAIRIVL.....QPLVLISDAIRS--....GLFSMSGWAGLATLKSpg..qyIIKLVYLVEIAAFALLIGFGVLL....IFLFFKKRESF.............PALFI..IFSLCLIAFLIGD....NVAAIYVrslTg....qPLINVIEIP..TTVISLLYSGAWLWYVAKSERVKETFV............
D2TK55_CITRI/27-166                 ........................................f-TKIGGFLYLPLLGLFI.....TALSHLVASYESFK....YLVDN-FYHLFFDA--......--KLFFIGTFTISLVVFLAAAWV....ISVFLRKKKSL.............PKLYI..GLMLLLIVLTALN....TWMLSVL...Ip....gIYIGSEELV..PLLRLIISACIWIPYFLKSVRVKRTFI............
A7MMM1_CROS8/6-144                  ........................................p-MRIGGWLLAPLAWLLM.....SLLSTTLAVALYVM....GLASPQVHQALSAQGT......TQVLFWYGSMLCAMAMWGYTLWL....TVAFFKCRQGV.............PRHYI..IWLLLTVLLAIK-....SFAFSPV...-......--SDALAVR..QLLFPLLAAALLVPYFKRSARVKQTFV............
W0HY46_9ENTR/8-137                  .........................................PRPIGGWLWAVVAWLGM.....TLLSATAMLLVYLW....--------FLL-QHAG......ALTPAALASLLTSGAMWLFTFWL....LRLLFRRSRRF.............PRLLI..LWLLVGVLLGIK-....TFAFAPV...-......--SDNLALR..VLFPPVLAAAVLVPYIKRSQRVRQTFI............
#=GC seq_cons                       ..........................................ptIuGWLlhshhhLll.....shlpssh.lhhhhh....shhp.thhphlhs.st......hhhhhhhhshhhslshhhaslal....hhhFh++ppph.............P+haI..lallhslllslh.....sahhssl.............-shslp..sllhslluuulalPYhtpSpRVKpTFh............
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