#=GF ID   DUF2981
#=GF AC   PF11200.12
#=GF DE   Protein of unknown function (DUF2981)
#=GF AU   Pollington J;0000-0002-8158-8998
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   Pfam-B_003040 (release 23.0)
#=GF GA   27.20 27.20;
#=GF TC   27.20 33.10;
#=GF NC   27.00 26.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -E 1000 --cpu 4 -Z 75585367 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR021366;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This eukaryotic family of proteins has no known function.
#=GF SQ   20
#=GS A0A2A9MPB1_9APIC/19-124   AC A0A2A9MPB1.1
#=GS A0A2H6K9W4_9APIC/1-309    AC A0A2H6K9W4.1
#=GS A0A125YX98_TOXGV/125-271  AC A0A125YX98.1
#=GS A0A1X1BI53_9APIC/3-354    AC A0A1X1BI53.1
#=GS A0A0G4E8A6_VITBC/106-193  AC A0A0G4E8A6.1
#=GS F0VQL2_NEOCL/110-200      AC F0VQL2.1
#=GS A0A1R4AA22_BABMR/33-164   AC A0A1R4AA22.1
#=GS F0VQL2_NEOCL/19-130       AC F0VQL2.1
#=GS Q1JSS1_TOXGO/19-122       AC Q1JSS1.1
#=GS A0A125YKK7_TOXGV/19-126   AC A0A125YKK7.1
#=GS A0A1R4AA22_BABMR/122-309  AC A0A1R4AA22.1
#=GS Q4UGN3_THEAN/23-340       AC Q4UGN3.1
#=GS A0A125YX98_TOXGV/19-141   AC A0A125YX98.1
#=GS A0A023B0B6_GRENI/197-286  AC A0A023B0B6.1
#=GS A0A2A9MPB1_9APIC/110-200  AC A0A2A9MPB1.1
#=GS A0A061D5C3_BABBI/24-410   AC A0A061D5C3.1
#=GS A0A2A9M808_9APIC/117-271  AC A0A2A9M808.1
#=GS L0AZI2_THEEQ/207-510      AC L0AZI2.1
#=GS A0A125YKK7_TOXGV/125-262  AC A0A125YKK7.1
#=GS J7MGV4_THEOR/23-410       AC J7MGV4.1
A0A2A9MPB1_9APIC/19-124              ..................................RAGLVVVAFIQVLTGISLYLALAYLRPSLHGAAYFMLLTNIVSSLLG..........MWGLWRRNQCMEIIYLATFLVCFSFLVITVLSFTNVAQALPKAPV-------.............GV-----------.............----------.------..------......----------------------------..----------------------....-----------------..................-------------...-------------------------.....----..-------------------------------------------------------------------------------------------------------------segfkeldtlph..............................
A0A2H6K9W4_9APIC/1-309               ..................................-----------------------------------------------..........--------------------------------MAELVHLLPKAPQIRDVSDFgamrsaaflrsggMKPHIFLRQRDMPldlgdddfstqgyDDLEINSGDDtNKHMHD.eHTAAPA......DVDITPLGQSDLNKQPKVAPIKQQSQQVgdEIRRNDLTAPSADVTRNDEAQN....VDVDLNDLEANGNAATN..................AMPKHGKGNENIH...ISRSATEP-TKEIVGTADSVSPQPDvaasvEPSNeaSTEDNKMDSFYDRLPLVPHLGETEGEAEEVAKEELPPETHDLTPEGISEVVAIYKIQKRPLKMAAAGLITMALLFNIYCYWVAVTFVLNKCTCLDELVSHPEQFTPLID..........................................
A0A125YX98_TOXGV/125-271             ..............................frnp-----------------------------------------------..........----------------------------------------------------.............-------------.............----------.------..------......----------------------------..----------------------....ITSYISEADQHAMLI--..................------------Q...ILQHSTLPELKMPEMEIPSLPKMPG.....IPN-..----------YEDIPFVPHLNQTEGETEELSAGELPPEAQNLTHQQQEEVTALVKMQKRPVKLAFAGVLGLLALFQLYGIWIIITFIMNKCMSFDELAGAPEQFRPLVG..........................................
A0A1X1BI53_9APIC/3-354               .................................l-QGLFFIAIQQFLLGISLYSVIHYLHPSMTQLAWLLFGANAISAVLG..........FFGALKRNIVIECVYLVFYFLALLLVFLTVLDMAELVHLLPKGPQMKDVYNFasmry..apilraGHPHVFLKQREEP.............----FELDDH.YDFEAD..DDEDPD......-MYPEELLDADTDASTDLEDIMSLKTP-..--EKTGQTSPPNQSDVTSKVTGd.inSKGPIEGTKTEQGAT--..................ADAKGTEETKSIH...IHQSKGKGQVNENVNKLGEQPIIAE.....-PV-..--KGAQNDSLYDHIPLVPHFGETEGEAEEVSKDELPPETHDLTPEGISEVVAIYKIQKRPLKMAAAGLLTIALMFNVYCYWVAVTFVLNKCTCLDELVSHPEQFTPLID..........................................
A0A0G4E8A6_VITBC/106-193             ...........................kdcgaga-----------------------------------------------..........----------------------------------------------------.............-------------.............----------.------..------......----------------------------..----------------------....-----------------..................-------------...-------------------------.....----..------------------------ADAEEVSARDLPREVDVLPEDEELEVASIAKIVKSAVRFGFILVFIILLLAYCAFVHVWFTFLLQGCKNITS-AAGPAQF-----ea........................................
F0VQL2_NEOCL/110-200                 ...........................vgvsegf-----------------------------------------------..........----------------------------------------------------.............-------------.............----------.------..------......----------------------------..----------------------....--AQLDTLPHFRNPITA..................QISDAEKHAMLIQ...ILQHSTLPELKMPDISIPPLPKMPE.....IPN-..----------YEDIPFVPHLNQTEGETEEVSADELPPE-----------------------------------------------------------------------..........................................
A0A1R4AA22_BABMR/33-164              ..................................RKGVFIIALSQLGIGVCMFFIISYLRPSLLTLAYAILIFFTIACSLG..........IISAAKKSVFITFIYLCVSIVGIALQAMIVAELSEVVHFLPKP---------.............-------------.............----------.------..------......----------------------------..----------------------....-----------------..................-------------...-------------------------.....----..-------------------------------------------------------------------------------------------------------------esdanpltiaptqdssssivgkqsnnsasadknpekknqvdn
F0VQL2_NEOCL/19-130                  ..................................RAGLMVVAVIQVLTGIALYLALAYLRPSLHGAAYFMLLANIVSALLG..........TWGLWRRNQCVEAIYLATFLVCFSFLVITVLSFTNVVHALPKAPV-------.............GVSEGFAQLDTLP.............----------.------..------......----------------------------..----------------------....-----------------..................-------------...-------------------------.....----..-------------------------------------------------------------------------------------------------------------hfrnpit...................................
Q1JSS1_TOXGO/19-122                  ..................................RRGLFVIAFIQLLTGIAVYMCYKYLRPSLHSVACSQLTIFSVSAVIG..........VIGAYRRNTTVEGFYFATFLASIAFLIIAILDFTDVVHMMPKAPE-GAVSSL.............-------------.............----------.------..------......----------------------------..----------------------....-----------------..................-------------...-------------------------.....----..-------------------------------------------------------------------------------------------------------------ekfeav....................................
A0A125YKK7_TOXGV/19-126              ..................................RRGLFVIAFIQLLTGIAVYMCYKYLRPSLHSVACSQLTIFSVSAVIG..........VIGAYRRNTTVEGFYFATFLASIAFLIIAILDFTDVVHMMPKAPE-------.............-------------.............----------.------..------......----------------------------..----------------------....-----------------..................-------------...-------------------------.....----..-------------------------------------------------------------------------------------------------------------gateaflqidretqnr..........................
A0A1R4AA22_BABMR/122-309             ..pesdanpltiaptqdssssivgkqsnnsasad-----------------------------------------------..........----------------------------------------------------.............-------------.............----------.------..------......----------------------------..----------------------....---------------KN..................PEKKNQVDNEIIHairLSKHKISPE-KMNLKRKTPLIAHSKf...nKPF-..HSTNLLANSFYDSLPFVPHLGETEGESEEVSKEELPPEIKNLNNEEKSEVIAIYKIQKRPIKLLSSALFSVILLFSIYNIWVIFTFFVNKCTNLDELKQQPEQFTPLVE..........................................
Q4UGN3_THEAN/23-340                  ..................................RNGVLVVSFTQILFGAGLYCTLHYLHPSLMGVAWFLLLLHFITGAIG..........LVSTFTRNLFLYVLYLILFAFSLVVVSMVALDMAEIVHFFPKAPELHDFSLL.............GFTAPFVTRFKTP.............NASVLFPFNF.FKLPND.tTGVLPQlp.hydEMVVTKFTMSHVDKHNHKHCNKRDSARF..DDD---VSSVLDNLDNPDDLKDlrnaLKQRLGDNNTNK-----..................------NGSGGVD...NYNAYDNPDGKVGGSKDLNSTKPSTn...gVSSA..GEKSKESDSFYDHLPFMPHPGETEGESEEVSKDEFPPETNDLTPEGKSEVVVLYKLQKRCNQLLLSYLLTT--IY----------------------------------piys......................................
A0A125YX98_TOXGV/19-141              ..................................RSGLVVIAFVQILTGVSLYLALGYLRPSLHGAAYFMLLTNIASALLG..........TWGLWRRNQCVETIYLATYLACLSFLVITVLSFANVVQALPKAPA-------.............GVSEGFTQLDKLP.............--HFRNPITS.YISE--..------......----------------------------..----------------------....-----------------..................-------------...-------------------------.....----..-------------------------------------------------------------------------------------------------------------adqham....................................
A0A023B0B6_GRENI/197-286             ...........................spakgvs-----------------------------------------------..........----------------------------------------------------.............-------------.............----------.------..------......----------------------------..----------------------....-----------------..................-------------...-------------------------.....----..--------------------------EEEISVDELPGVYSELSDEGQKLVQAQMKNMKHVAKICCGATLMVLTGIRLYFLWTTLSWALNKCISFDVLEDAPDQFDALMD..........................................
A0A2A9MPB1_9APIC/110-200             ..........................vgvsegfk-----------------------------------------------..........----------------------------------------------------.............-------------.............----------.------..------......----------------------------..----------------------....---ELDTLPHFRNRITM..................QPSAAVEHAMLIQ...ILQHSKLPALKMPEISIPPLPKMPE.....IPK-..----------YDDIPFVPHLNQTEGQTEEVSADELPPE-----------------------------------------------------------------------..........................................
A0A061D5C3_BABBI/24-410              ..................................RNGLFFIAIQQFLLGVSLYSVIHYLHPSLTKLAWLLFGVNAISAVLG..........FLGALKRSMVIECVYLVFYFISLTLVFLTVLDMAELVHLLPKAPQIRDVSDFgalrsaaflraggMKPHVFLRQRDMPldlgeddfstqgdDDLEINPDDD.SKLRND.gHNALPT......DVDIAPLRSPDLDRQQEISPAKQQRQHVvdESGRSDVATPAAVATNNAEGAT....VDSDLRDLEANRNATTT..................TAPKRGRDNANVH...VPKALAAP-TKENEVTADSLPAQAEvadsvEPAKepNAEDAKMESFYDRLPLVPHLGETEGEAEEVSKEELPPETHDLTPEGISEVVAIYKIQKRPLKMAAAGLTTMALLFNIYCYWVAVTFVLNKCTCLDELVSHPEQFTPLID..........................................
A0A2A9M808_9APIC/117-271             ............agpiqrqrgsrtasflqlkkgt-----------------------------------------------..........----------------------------------------------------.............-------------.............----------.------..------......----------------------------..----------------------....-----------------..................-------------...HPQSFPVPLRGQSSTHVTVLNALRA.....EPVR..AAQDVQ--KALETLPFVPHIGETEGESEEISVDELPPEAKTLTQESQATVIAITKMQKRPVKLAFAGVFGALLLAHLYFGWIILTFLLNKCMSLDELTGQPEQY-----ad........................................
L0AZI2_THEEQ/207-510                 ............................ifkhfl-----------------------------------MLVVAKDKPPQG..........FLGAWKRSMTLEVAYIVVYIISMTFVSMTALDLADLVHFLPRAPQIH--VRF.............ISILSFLPQDLSF.............YGMNLAPPFS.LEHPHLssPPTLPT......GNIPLVLHKNAIFPNHGISRLQYIKEQVepLAKPTDSKADTAAPLSPVAKST....FDASINDKNSATMS---..................---QASVGKGDGS...VVKKATGP---------------TQ.....APAK..NEAKEDTGTFYDNLPFVPHLGESEGETEEVSKDEFPPETGDLSPEGKSEVVVMYKLQKRPLKILASAFITLCFFFYTYCLWIVFTFVLNKGTDLDALTRHPEQFTPLIE..........................................
A0A125YKK7_TOXGV/125-262             nrpsslparrwhyshgsfaantsrltqggwaskq-----------------------------------------------..........----------------------------------------------------.............-------------.............----------.------..------......----------------------------..----------------------....-----------------..................-------------...-------------------------.....----..-----DIQKTLETLPFVPHIGETEGESEEISIGELPPEAKELPTKAQNMVITITKMQKRPVKLAFAGVFGTLLLFHLYFGWIILTFLMNKCMSLDELTGQPEQFQPLI-r.........................................
J7MGV4_THEOR/23-410                  ..................................RNGVFVTSFTQLLFGVALYCILHYLHPSLHGVAWFLLGLHVLVAVLGyvflclklcrFVGALKRSLGFHATYMVFYAVSMVFVAMIALDMSELVHFLPKAPQMHDFSMF.............QTNTPLITKFKSP.............NSKVLFPFNF.YKDPFL..TNNMPDlsdlgnGKLIAKYSVTEIDLHNPQNPIVSYSGTI..SNEPFDANSPNGNMDGTTGLPTs..aGDAGLDDLDKLKKLLREklndsnptnstdnnsgprSDTAYPVGATPSS...SPTTATTPDNNPTSSPTSAPTATPD.....KPAS..QSGGDKDDSLYDHIPFLPHPGETEGESEEVSKDEFPPETNDLSPEGKSEVVVMYKMQKRSVKFAASAFLLVCLIFYMYSFWVAFTFAMNKCTCLDELSAQPDQFTPLVD..........................................
#=GC seq_cons                        ...........................................................................................................................hsplsphhP+s........................................................................................................................................................................................................................................h-plPhhPH.spoEG-sEElShcEhPPEht.Ls.pt...V.s.hK..Kps.phh..hhh.h..hh............................................................................
//