#=GF ID   DUF3236
#=GF AC   PF11576.3
#=GF DE   Protein of unknown function (DUF3236)
#=GF AU   Pollington J
#=GF SE   pdb_3brc
#=GF GA   25.00 25.00;
#=GF TC   121.40 120.20;
#=GF NC   21.90 20.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR012019;
#=GF CC   This family of proteins with unknown function appears to be
#=GF CC   restricted to Methanobacteria.
#=GF SQ   27
#=GS Q8TZB7_METKA/2-155  AC Q8TZB7.1
#=GS D3E196_METRM/3-155  AC D3E196.1
#=GS Q6LX55_METMP/3-156  AC Q6LX55.1
#=GS H1KWM5_9EURY/1-154  AC H1KWM5.1
#=GS D7DUD3_METV3/4-167  AC D7DUD3.1
#=GS F0S2B9_DESTD/5-157  AC F0S2B9.1
#=GS A6VH82_METM7/3-156  AC A6VH82.1
#=GS G0H2X1_METMI/3-156  AC G0H2X1.1
#=GS D5VQF5_METIM/6-158  AC D5VQF5.1
#=GS A2SU94_METLZ/6-159  AC A2SU94.1
#=GS A4FW26_METM5/3-156  AC A4FW26.1
#=GS E3GZ38_METFV/3-156  AC E3GZ38.1
#=GS A5UKQ1_METS3/3-156  AC A5UKQ1.1
#=GS A6UWJ5_META3/3-162  AC A6UWJ5.1
#=GS E1RJE0_METP4/3-156  AC E1RJE0.1
#=GS C7P7L0_METFA/1-154  AC C7P7L0.1
#=GS F6BF29_METIK/1-154  AC F6BF29.1
#=GS D2ZN25_METSM/3-156  AC D2ZN25.1
#=GS A9A9G7_METM6/3-156  AC A9A9G7.1
#=GS C9RF72_METVM/1-154  AC C9RF72.1
#=GS A6UQE0_METVS/3-156  AC A6UQE0.1
#=GS O27213_METTH/2-155  AC O27213.1
#=GS O27213_METTH/2-155  DR PDB; 3BRC B; 2-155;
#=GS O27213_METTH/2-155  DR PDB; 3BRC A; 2-155;
#=GS Y488_METJA/4-157    AC Q57912.1
#=GS D9PY09_METTM/2-155  AC D9PY09.1
#=GS B9AGK8_METSM/3-156  AC B9AGK8.1
#=GS F8AN83_METOI/3-162  AC F8AN83.1
#=GS D3S6G6_METSF/1-154  AC D3S6G6.1
Q8TZB7_METKA/2-155             ..LKETLLKAWWESWEGTRRGDEEREVEGLREYLTSADRLAVVTGNEDKLRAVNKVLRRF..........G......LPEAEMIRVPTEMADATPCPAIFKAIMGVQVSDADVVIARGRLGVPGSGAMTVFMDARCRLLTAALSPPHVLHEMSVKEAMEREAEEALRRLGMR.
D3E196_METRM/3-155             ..FEESIRKASIQSYEGTRKGDTIEEIEAIQNYIRNA-KIVVPNKNGIKVEVINEVLAKF..........N......IPPAEYLQVNTNYADFSRMPAIAKAMIAVDQSDADLVIARGRLGIPGSGSFLVFMDSKSRILTAATSPSHIIHNQPLEKTVYKETLEALKKVGFK.
Q6LX55_METMP/3-156             ..IENTIKSAYEESLNNARFGDKIEEIDAIQSTIKSAKNVTVATSNEKKFKVVSDIISRI..........T......DANISMLEIPTNSADLTRMPALNKGLIAVDSSDADLIITRGRLGIPGSGSLLLIMDKKGRILTGSVSPSSIIHKNPIDKTVELELITALERIGI-v
H1KWM5_9EURY/1-154             ..MEKIIKKAYTESIENERKGDKEEEVEAIKRIILNAKKIIIATNNQKKFKVIGDILSHI..........V......NAKIEMLNINTNYADLTRMPAVNKGLMAVDTEKADLIIARGRLGVPGSGSMLVIMDGKGRILSASLSPSSVLHKEDIEVRIKKELIDALKRIGI-d
D7DUD3_METV3/4-167             .v-NKIIKNSYIHSLENCRNGDQIEEIEAIQNVIKNSKKIVVATSNGKKFKVVKNIILKVldnhcndnnqN......NVNIEMLDICTNSADLTRMPALTKGLIAVDITDADLIIARGRLGIAGSGSLLLLMDGKGRILTGAMSPSSIIHKESIEHKMEFELLQALKKIGI-m
F0S2B9_DESTD/5-157             kl--ELFKNAFLESLVGNRKGDKPEETALLRERILKG-KIGIVTNNKKKFTIAKKTISLF..........G......IKNISQIEIPTEIFDLTEIPTLSKALAGRFFKNCNFYVARGRLGAPGSGALTIMIDEFGHVISAVTSPPHHLHKFSLETSVFLDIFRLLKRLGF-t
A6VH82_METM7/3-156             ..IEKTIKCAYDESINNARFGDKFEEIEAIQSTIKSAKSVVVATRNEKKFKVVSDIISKI..........T......DADISMIEIPTNSADLTRMPALNKGLIAVDSSNADIVVSRGRLGIPGSGSLLIILDKKGRILTGSVSPSSIIHKNPIEKTVELELINALERIGI-m
G0H2X1_METMI/3-156             ..IENTIKSAYEESLNNARFGDKIEEIDTIQSTIKSAKNVTVATSNEKKFKVVSDIISRI..........T......DANISMLEIPTNSADLTRMPALNKGLIAVDSSDADLIITRGRLGIPGSGSLLLIMDKKGRILTGSVSPSSIIHKNPIDKTVELELIVALERIGI-v
D5VQF5_METIM/6-158             .l-SNLIKRAYLQSLKGEREGDREEEVEAIRETIKSAKKIVVATNNEKKFKVIKNIISEI..........C......DAEIKMIDLDTKVADLSRMPAIAKGLIALDVEDADLYIARGRLGVPGSGSMLVIMDSKGRILTASLSESSAIHKESLERRIEKEVKDALRRVGL-.
A2SU94_METLZ/6-159             ..IDCCVSSAYSQSLNGTRLGDTAEETMSIREYIKSSRHIVVPNHDDRKIAVINSVLSSF..........G......LPRAVHLCIPTNSPDLTRTPAVSKALMALDITGADLVIARGRLGVPGSGSMLVIMDSRGRILSASLSPSHLYHAKSISDAVTHEMEEALVRVGFQ.
A4FW26_METM5/3-156             ..IEETIKTAYGESLNSARFGDKFEEIDAIQSIIKSAKSVVVATRNEKKFKVVFNIISKI..........T......DANISMIEIPTNSADLTRMPAVSKGLIAVDSSDADIIISRGRLGIPGSGSFLLIMDKKGRILTGSISPSSIIHKNPIDKTVELELINALERIGIK.
E3GZ38_METFV/3-156             ..MEKLIKKAYVESVEGRRQGDKIKEVKEIQKYILNAKNIVVPNKTKEKVKAINEVLEKF..........G......IQKAKHLKFYTDACDLNRTPAISKALMALDIVDCDLVIARGRLGVPGSGSMLVIMDSKGRILSAALSPPHIIHKKSVEKAVKDEMTTALKRIGL-n
A5UKQ1_METS3/3-156             ..FEEMIKKALDESRNNCRLGDTLEEVREIQNYIKNAEKIYIPNKNGIKVDVLNKVLREY..........N......LPSAKILQINTNEADSNRSPAFAKAIMALDVCDADLIIARGRLGLPGSGSLLLFVDNKGRILTCGTSPSHAISQKTLEDAVYEEANEALQKIGFR.
A6UWJ5_META3/3-162             nn--KIIKDAYLESITNKRCGDKIEELLYIQNKILNAKKIVVATNNKKKFDIINNILISL..........FknydkpLPTIEKLDLPTNSVDLTRFPAINKGLIAVDTSDADIVIARGRLGAPGSGSMLIIMNNKGRCLSASLSPTSLIHKKDIEDAVKDELNEALERIGI-n
E1RJE0_METP4/3-156             ..LEDFISKACIESSTGIRRGDKREETEGIREYILNSKTIVIPNCNDEKVAAVNEVLDEL..........D......LPKAGHLNIHTDSCDVSRMPAVTKALMALDMTDADLIIARGRLGVPGSGSMLVIVDCKGRLLSASISPSHHIHGKTVYQAVKDEMTDALSRIGF-d
C7P7L0_METFA/1-154             ..MEEIIKNAFIESINNTRRGDKREEVKKIQEKIINAKKIVVATNNQKKFKVIRDIMLRI..........C......NAEIKMLNIDTRFADLTRMPALNKGLMAVDTEKADLYIARGRLGVPGSGSMLIILDEKGRVLTAALSPSSVIHKEDIEERIKKELIEALKRIGI-d
F6BF29_METIK/1-154             ..MENLIKKAYTQSIKNKRRGDEEEEVEAIKRIILNAKKIIIATNNQKKFKVISDILSRV..........V......NAKIEMLNINTNCADLTRMPAVSKGLIAVDTEEADVVIARGRLGVPGSGSMLVIMDGKGRILSASLSPSSVVHKEDIETRIKKEIIDALKRVGI-e
D2ZN25_METSM/3-156             ..FEEMIKKALDESRNNCRLGDTLEEVQEIQNYIKNAEKIYIPNKNGIKVDVLNKVLREY..........N......LPSAKILQINTNEADSNRSPAFAKAIMALDVCDADLIIARGRLGLPGSGSLLLFVDNKGRILTCGTSPSHAISQKTLEDAVYEEANEALQKIGFR.
A9A9G7_METM6/3-156             ..IEETIKTAYEESLNNTRFGDKFEEIEAIQSTIKSAKSVVVATRNEKKFKVVFDIISKI..........T......DANISMIEIPTNSADLTRIPAVNKGLIAVDSSNADIVISRGRLGIPGSGSFLLIMDKKGRILTGSVSPSSIIHKNPIENTVELELLNALERIGIK.
C9RF72_METVM/1-154             ..MEEIIKRAYLESLDGRRFGDKKEEVEKIREKILSAKKIVVATNNQKKFNIIKDIISKI..........C......NATITMIDIDTRFADLTRVPALNKGLMALDTETADLVIARGRLGVPGSGSMLVILDGKGRILTASLSPSSIVHRENIEDRIKKEIIEALSRIGI-n
A6UQE0_METVS/3-156             ..LEKLISNAYAESLKNMRFGDKSEELSEIQSIILNSKRIVVATNNEKKFKVVFDIISKV..........C......NAEVLMLGISTNSADLTRMPALSKGLIAVDSTDADVVISRGRLGIPGSGSLLLIMDKKGRILTGAMSSSSLIHKNRIEDSINLELTIALERIGI-l
O27213_METTH/2-155             ..LEDLIGKAYLESAEDRRRGDRSEEVEAIRKYIRSARRTVVPNWNAEKVDAINDVLRSF..........N......LREAEHLQFNTNWADLTRMPAVTKALMALDISGADLVIARGRLGVPGSGSLLVIMDSRGRLLSAAMSPPHVIHSMEVREAVRSEMTHALERIGFK.
#=GR O27213_METTH/2-155  SS    ..HHHHHHHHHHHHHTT---S--HHHHHHHHHHHHH-S-EEE----HHHHHHHHHHHHHT..........T......----EE--S--GGGGGSSSHHHHHHHHHHHHH--SEEEEEEE-SSTTS-EEEEEEETTS-EEEEEEE--TTTS---HHHHHHHHHHHHHHTTT--.
Y488_METJA/4-157               ..MEEIIKKAFIESINNIRRGDKEEELKKIQEKIVNAKKIVVATNNQKKFKVIRDIMLRV..........C......NAEIKMLDIDTRFADLTRMPALTKGLIALDIEKADLYIARGRLGAPGSGSMLVILDEKGRVLTASLSPSSVIHKEDIEERIKKELIEALSRIGI-s
D9PY09_METTM/2-155             ..LEDIIASAYLESAEDRRRGDREEEVRAVRDYISGAQRIVVPNWNREKVDVINEVLRSF..........N......LREAEHLQFNTNWADLTRMPAVTKALMALDISGADLVIARGRLGVPGSGSLLVIMDSRGRILSAAMSPPHVIHEMGVQEAVRSEMTHALERIGFK.
B9AGK8_METSM/3-156             ..FEEMIKKALDESRNNCRLGDTLEEVQEIQNYIKNAEKIYIPNKNGIKVDVLNKVLREY..........N......LPSAKILQINTNEADSNRSPAFAKAIMALDVCDADLIIARGRLGLPGSGSLLLFVDNKGRILTCGTSPSHAISKKTLEDAVYEEANEALQKIGFR.
F8AN83_METOI/3-162             ..IEDSIKRAYEESCHGNRMGDKKEEVELIRQTILNAKNIVIATNNPKKFKVVKDILLEIldk....eknN......NISVSKIDLHTEVSDLTRMPVLNKGLIAVDISNADIVIARGRLGVPGSGSMLLIMDNKGRILTGSLSPPSVIHKRNIEDTVKSELIDALKRIGIR.
D3S6G6_METSF/1-154             ..MEEIIKNAFIESINNVRRGDKEEELKKIQEKIINAKKIVVATNNQKKFKVIRDIILRV..........C......NAEIKMLDIDTRFADLTRMPAITKGLLALDIEKADLYIARGRLGVPGSGSMLVILDEKGRILTASLSPSSVVHKEDIEKRIEKEMIEALGRVGIK.
#=GC SS_cons                   ..HHHHHHHHHHHHHTT---S--HHHHHHHHHHHHH-S-EEE----HHHHHHHHHHHHHT..........T......----EE--S--GGGGGSSSHHHHHHHHHHHHH--SEEEEEEE-SSTTS-EEEEEEETTS-EEEEEEE--TTTS---HHHHHHHHHHHHHHTTT--.
#=GC seq_cons                  ..hEchIKpAYhESlpspRhGD+hEElctIpphIhsAK+IVVsTpNpKKFcVlp-llpcl..........s.......splphLpIsTN.ADLTRMPAlsKuLhAlDhscADLlIARGRLGlPGSGShLlIMDsKGRILTuulSPSplIHKpslEcsVcpEhhcALcRIGl..
//