GenomeNet

Database: Pfam
Entry: DUF3242
LinkDB: DUF3242
Original site: DUF3242 
#=GF ID   DUF3242
#=GF AC   PF11586.4
#=GF DE   Protein of unknown function (DUF3242)  
#=GF AU   Pollington J
#=GF SE   pdb_1vr8
#=GF GA   25.00 25.00;
#=GF TC   25.60 124.10;
#=GF NC   21.20 24.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   16948158
#=GF RT   Crystal structure of an ORFan protein (TM1622) from Thermotoga
#=GF RT   maritima at 1.75 A resolution reveals a fold similar to the
#=GF RT   Ran-binding protein Mog1p. 
#=GF RA   Xu Q, Krishna SS, McMullan D, Schwarzenbacher R, Miller MD,
#=GF RA   Abdubek P, Agarwalla S, Ambing E, Astakhova T, Axelrod HL,
#=GF RA   Canaves JM, Carlton D, Chiu HJ, Clayton T, DiDonato M, Duan L,
#=GF RA   Elsliger MA, Feuerhelm J, Grzechnik SK, Hale J, Hampton E, Han
#=GF RA   GW, Haugen
#=GF RL   Proteins. 2006;65:777-782.
#=GF DR   INTERPRO; IPR021636;
#=GF CC   This protein from Thermotoga maritima is a hypothetical ORFan
#=GF CC   protein, TM1622, whose structure has been determined. The
#=GF CC   protein is composed of seven beta strands and three alpha
#=GF CC   helices [1].
#=GF SQ   13
#=GS A8F4M0_THELT/26-153  AC A8F4M0.1
#=GS B7IF46_THEAB/28-157  AC B7IF46.1
#=GS A5ILW0_THEP1/26-152  AC A5ILW0.1
#=GS F7YVF9_9THEM/27-154  AC F7YVF9.1
#=GS K2NMC8_9THEM/28-157  AC K2NMC8.1
#=GS Q9X1V7_THEMA/26-152  AC Q9X1V7.1
#=GS Q9X1V7_THEMA/26-152  DR PDB; 1VR8 A; 26-152;
#=GS H9UE66_FERPD/35-163  AC H9UE66.1
#=GS D2C3G6_THENR/26-152  AC D2C3G6.1
#=GS B1LBD2_THESQ/26-152  AC B1LBD2.1
#=GS B9K7S9_THENN/25-152  AC B9K7S9.1
#=GS A6LP92_THEM4/28-157  AC A6LP92.1
#=GS A7HMP8_FERNB/36-164  AC A7HMP8.1
#=GS J9HGY4_9THEM/26-152  AC J9HGY4.1
A8F4M0_THELT/26-153             PRVYSISSAVKSLQD.SYLLVFVEEV.DG.YGPV.EAKGVVASYvhDGKNY.LFYGFKFYDES.PKVYWKKIVKEIGIWSSRTYF..DLLNSGLYSSKKDGKYIVVWWKDVWMFIVESSSNAEDFANYVMNWFAKL..
B7IF46_THEAB/28-157             PGSFSLKSAISLLDSyEYPLVETGEI.NSlYGVQ.LNRGMYGVF..KNFDG.MFYVFKYEDEKlTKNDWNRLIKTFGSVLKINYFkfSLFDRGYLQTKFEDLNVITWWKGNWLFVITGNN-SKEFFEYINKVYGMI..
A5ILW0_THEP1/26-152             PEAYSLDTAIFVLETrDYRLSDVKEI.DS.YGDV.EMKGKVAVF..ETEYG.PVFLYVYKGEE.AKKIWKKLNGRAGFVSIRSVL..DLPNMGKFSTVSDGKKIIAWWRKNWLFVVEGKNGVEEFVKHVYRVYEEM..
F7YVF9_9THEM/27-154             PDAFSASSALRIVQN.HYRLVLIEEI.DG.YEDV.QMKGMVALYikDNKQF.LLYAFKFQGES.PRKYWSKIVKNFGIWSSRTYL..DFPTSGLYSTRKSGKEIVVWWKNRWLFIAEGREDTETFASQVMDVYSRI..
K2NMC8_9THEM/28-157             PGSFSLKSAISLLDSfEYHLVETGEI.NSlYGVQ.LNRGMYGVF..KNFDG.MFYVFKYEDEKlTKNDWNRLIKTFGSVLKINYFkfSLFDRGYLQTKFEDLNVITWWKGNWLFVITGNN-SKEFFEYINKVYGMI..
Q9X1V7_THEMA/26-152             PEAYSLDTAIFVLETrDYRLSDVKEI.DS.YGDV.EMKGKVAVF..ETEYG.PVFLYVYKGEE.AKKIWKKLNGRAGFVSIRSVL..DLPNMGKFSTVSNGKKIVAWWRKNWLFIVEGKNGVEEFVKHVYRVYEEM..
#=GR Q9X1V7_THEMA/26-152  SS    -TTS-HHHHHHTT-BTTBEEEEEEEE.EE.ETTE.EEEEEEEEE..EETTE.EEEEEEEESTT.HHHHHHHHHT-XXX---EEEE..E-SSEEEEEEEETTEEEEEEEETTEEEEEEESS-HHHHHHHHHHHHHTS..
H9UE66_FERPD/35-163             PASYSVEAAINVIAN.KYMLLDSGWV.NG.FGDMeLGEGRYATF..DGVDG.FLMVFKYEDPDqAKASWDKITKRYGNPLRLKYLkiNMGTYGVFTIRLENTDLYSWYKENWLFVITGDK-IEKFVMDVNNIYKTI..
D2C3G6_THENR/26-152             PEAYSLDTAIFVLETrDYRLSDVKEI.DS.YGDV.EMKGKVAVF..ETDYG.PVFLYVYKGEE.AKKIWKKLNSRAGFVSIRSVL..DLPNMGKFSTVSDGKKIIAWWRKNWLFVVEGKNGVEEFVKHVYRVYEEM..
B1LBD2_THESQ/26-152             PEAYSLDTAIFVLETrDYRLSDVKEI.DS.YGDV.EMKGKVAVF..ETEYG.PVFLYVYKGKE.AKKIWKKLNGRAGFVSIRSVL..DLPNMGKFSTVSNGKKIVAWWRKNWLFIVEGKNGVEEFVKHVYRVYEEM..
B9K7S9_THENN/25-152             PDAYSVETALQILENqEYRLVDIKEV.DQ.YRDV.EMKGKVAIF..ESKTGdVLLLYAYRGED.AKQVWKAVKKKSGFLSVRSIL..ELPNMGKFSTILDGKRIVSWWKKRWFFTVEGRNGVDKFVKHVFRVYG--vl
A6LP92_THEM4/28-157             PGSFSLKSALLILDGfQYPLTSVVKVnEV.YGAK.LGNGICGMF..ENFNG.TFYVFKYVSSNvAKSNWKNFRKQVGGPLKINYLtySWLDRGYFQVKYKSIDIISWWKDNWLFIITGKD-AKEFFNYINEVYGEI..
A7HMP8_FERNB/36-164             PSSYSQEAAINVLSN.KYYLIDSGYI.EG.FGDIyLGEGRYAIF..DGVDG.IFMVFKYDDEEhAKESWNKITKKYNNPFKLKYFkvNMGDYGVFTLRLENTDLYVWYKDNWLIVISGDK-IDNFVKDVNEIYKTI..
J9HGY4_9THEM/26-152             PEAYSLDTAIFVLETrDYRLSDVKEI.DS.YGDV.EMKGKVAVF..ETEYG.PVFLYVYKGKE.AKKIWKKLNGRAGFVSIRSVL..DLPNMGKFSTVSNGKKIIAWWRKNWLFIVEGKNGVEEFVKHVYRVYEEM..
#=GC SS_cons                    -TTS-HHHHHHTT-BTTBEEEEEEEE.EE.ETTE.EEEEEEEEE..EETTE.EEEEEEEESTT.HHHHHHHHHT-XXX---EEEE..E-SSEEEEEEEETTEEEEEEEETTEEEEEEESS-HHHHHHHHHHHHHTS..
#=GC seq_cons                   PcuYSL-oAIhlL-sh-Y+LsDlcEI.Du.YGDV.phKG+VAlF..-scpG.hlalatYcuE-.AKphWKKlsK+hGhlShRohL..-LsshGhFSThh-GKcIluWWKcNWLFllEG+NslEEFVcaVh+VYpch..
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