GenomeNet

Database: Pfam
Entry: DUF3314
LinkDB: DUF3314
Original site: DUF3314 
#=GF ID   DUF3314
#=GF AC   PF11771.3
#=GF DE   Protein of unknown function (DUF3314) 
#=GF AU   Coggill P
#=GF SE   SwissProt (UPF0575)
#=GF GA   25.00 25.00;
#=GF TC   150.50 42.80;
#=GF NC   19.80 19.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR021748;
#=GF CC   This small family contains human, mouse and fish members but the
#=GF CC   function is not known.
#=GF SQ   44
#=GS G3NES0_GASAC/95-255   AC G3NES0.1
#=GS D2HFY9_AILME/68-225   AC D2HFY9.1
#=GS CS067_MOUSE/92-249    AC Q8CF25.1
#=GS CS067_HUMAN/92-249    AC A6NJJ6.2
#=GS G1KT66_ANOCA/92-245   AC G1KT66.1
#=GS H3B7D7_LATCH/115-280  AC H3B7D7.1
#=GS CS067_DANRE/162-331   AC A3KNM4.1
#=GS G3UZG4_MOUSE/120-243  AC G3UZG4.1
#=GS H2L3V9_ORYLA/94-249   AC H2L3V9.1
#=GS F1SD55_PIG/92-249     AC F1SD55.1
#=GS G7PZL1_MACFA/92-249   AC G7PZL1.1
#=GS F6NVE5_DANRE/84-175   AC F6NVE5.1
#=GS A2BGV3_DANRE/84-175   AC A2BGV3.1
#=GS G3HD10_CRIGR/176-321  AC G3HD10.1
#=GS F8VW47_HUMAN/178-335  AC F8VW47.1
#=GS H2NXS5_PONAB/92-249   AC H2NXS5.1
#=GS G1SVB1_RABIT/92-250   AC G1SVB1.1
#=GS A2BGV4_DANRE/95-239   AC A2BGV4.1
#=GS F6VPD7_HORSE/92-253   AC F6VPD7.1
#=GS G1M3C2_AILME/92-249   AC G1M3C2.1
#=GS Q4RZS2_TETNG/1-161    AC Q4RZS2.1
#=GS G3Q6L9_GASAC/95-255   AC G3Q6L9.1
#=GS G3QIT6_GORGO/92-249   AC G3QIT6.1
#=GS F1Q8A6_DANRE/162-331  AC F1Q8A6.1
#=GS H0VQ02_CAVPO/92-249   AC H0VQ02.1
#=GS B7ZWF8_MOUSE/91-248   AC B7ZWF8.1
#=GS H0WKS6_OTOGA/198-233  AC H0WKS6.1
#=GS G7NLZ2_MACMU/92-249   AC G7NLZ2.1
#=GS D4A283_RAT/120-277    AC D4A283.1
#=GS H2QFJ9_PANTR/178-335  AC H2QFJ9.1
#=GS G5BYT6_HETGA/92-249   AC G5BYT6.1
#=GS F7G4Z8_MONDO/92-252   AC F7G4Z8.1
#=GS G3W612_SARHA/1-152    AC G3W612.1
#=GS Q4TCQ0_TETNG/1-141    AC Q4TCQ0.1
#=GS G1Q085_MYOLU/92-249   AC G1Q085.1
#=GS H0WKS6_OTOGA/92-194   AC H0WKS6.1
#=GS F6UZF9_MOUSE/121-278  AC F6UZF9.1
#=GS G3UZX3_MOUSE/120-277  AC G3UZX3.1
#=GS B2RVM9_MOUSE/92-249   AC B2RVM9.1
#=GS F7I3C5_CALJA/114-271  AC F7I3C5.1
#=GS E1BDZ6_BOVIN/92-249   AC E1BDZ6.1
#=GS G1TF94_RABIT/92-250   AC G1TF94.1
#=GS G3TMK5_LOXAF/92-249   AC G3TMK5.1
#=GS G1RSK2_NOMLE/92-249   AC G1RSK2.1
G3NES0_GASAC/95-255              ..t-YASCNVLCLDETNPI....SLSHFCIGQSQLG.AL.RVKAFRYCKPTPYLARLDTG.LYKRMRWNVERHR.D.EYGEGQIVCD..........--TEYYFLCYEDIPNrHAD........AGRDHDGV..SHSNVVRMWSIGQWQQVTP.--E.TDDIDHWVLCEVPQANYHKLLYFGSEEPSSCSGTEHLQQLL.............
D2HFY9_AILME/68-225              ...MYASFGFVDLEETDPL....SISCFFCGRFSISpSH.EVSIFRYCAPAAYTASRFPRyLYKKMRWNLETTP.E.PSGRGQD---..........SHVDYYFLCYRDTWE.---........DTGKSPAN..SCPQIQKLWSIGRWVPLGP.--D.EDDLYSWILCPQPPGDYQQLLTIGFEEPSHMLATDLLVQIL.............
CS067_MOUSE/92-249               ...MYASFGFVDLEETNPL....SISCFFCGRFSISpSH.DVSIFRYCTPAAYTASHFPRyLYKKMRWNLETTT.E.ASSQGAD---..........SHVDYYFLCYRDTWE.---........DAGQGPAN..SCPQIQKLWSIGRWMPLGP.--A.EDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQIL.............
CS067_HUMAN/92-249               ...MYASFGFVDLEEMNPL....SISCFFCGRFSISlSH.EVSIFRYCAPTAYTASRFPRyLYKKMRWHLEATP.E.APGRGQD---..........SLVDYYFLCYRDTWE.---........DTGQSPAN..SCPQIQKLWSIGRWVPLGP.--A.EDDLYSWILCPQPLGDYQQLLTIGFEEPTPTLATDLLVQIL.............
G1KT66_ANOCA/92-245              ...MYASFSFVSLEDKDPS....SVSCFFCGKFWLN.EMrQVSIFRYSISAPYTAAHVPHnLYKKMRWNIDILE.K.SAGRNQT---..........PKTEYYFLCFRDTGD.---........-------E..ATVKMQKLWSIGRWVPVDP.DSEhSADVLSWVLCHHPMGDYQQLLTIGFEEPSHTLATDLFVQM-f............
H3B7D7_LATCH/115-280             ...MFASFGYILLEETDPC....SISCFYRGQFRLGpSY.HVSIFRYCIGTPYTAALEPRhLYKRMRWNVDIME.ElSNGDGSE---..........PRTEFYFLCYRDTEP.ELG........VTNQSAAKnvTTTKPHRLWSIGRWIQTEP.DPT.QSDLFSWILCKQPKGDYESLLTIGFEEPSQILATDLLVELL.............
CS067_DANRE/162-331              ...LFASFSFCSLEESDPL....SVSHFSIGQCQID.NM.KVSIFRYCCPTPFLASSLTG.LYKRMRWNVEREI.E.GEGDGKTYDS..........--AEFYFLCCEDVIE.AADdqnedrssEGESTETD..SESKVSRIWSIGRWVQTYP.DPN.TEDIIDWVLCSLPCGQYKQLLCLGNEEPSSCTATDCLLGAL.............
G3UZG4_MOUSE/120-243             ...MYASFGFVDLEETNPL....SISCFFCGRFSISpSH.DVSIFRYCTPAAYTASHFPRyLYKKMRWNLETTT.E.ASSQGAD---..........SHVDYYFLCYRDTWE.---........DAGQGPAN..SCPQIQKLWSIGRWMPLGP.--A.EDDLDSW----------------------------------.............
H2L3V9_ORYLA/94-249              ..t-YARYGILSVDEAEPN....SVSHFCIGRCRLG.RL.KMTIFRYCKPTPYLSRGDTG.LYKRMRWNVERLPaD.ADGDEEEGES.........dRHTDYFFLCCEDLPN.---........-------Q..SDQGALRVWSIGQWVQLDP.DPQ.TDDLYDWILCDVPGGDFQKLLCLGCTEPSSCSATDVLLQLL.............
F1SD55_PIG/92-249                ...MYASFGFVDLEETDPL....SISCFFCGRFSISpSH.EVSIFRYCAPAAYTASRFPRyLYKKMRWNLEITP.E.PSSRGQD---..........SHVDYYFLCYRDTWE.---........DTGKSPAS..SCPQIQKLWSIGRWVPLGP.--A.EDDLYSWILCPQPPGDYQQLLTIGFEEPSHMLATDLLVQIL.............
G7PZL1_MACFA/92-249              ...MYASFGFVDLEETNPL....SISCFFCGRFSISlSH.EISIFRYCAPTAYTASRFPRyLYKKMRWHLEATP.E.APGRGQD---..........SLVDYYFLCYRDTWE.---........DTGQSPAN..SCPQIQKLWSIGRWVPLGP.--A.EDDLYSWILCPQPLGDYQQLLTIGFEEPTPMLATDLLVQIL.............
F6NVE5_DANRE/84-175              ...----------------....-------------.--.--------------------.-------------.-.----------..........-----YFLCCEDVIE.AADdqnedrssEGESTETD..SESKVSRIWSIGRWVQTYP.DPN.TEDIIDWVLCSLPCGQYKQLLCLGNEEPSSCTATDCLLGAL.............
A2BGV3_DANRE/84-175              ...----------------....-------------.--.--------------------.-------------.-.----------..........-----YFLCCEDVIE.AADdqnedrssEGESTETD..SESKVSRIWSIGRWVQTYP.DPN.TEDIIDWVLCSLPCGQYKQLLCLGNEEPSSCTATDCLLGAL.............
G3HD10_CRIGR/176-321             ...MYASFGFVDLEETNPL....SPSH---------.--.DVSIFRYCTPAAYTASHFPRyLYKKMRWNLETTT.E.ASSQGPD---..........SRVDYYFLCYRDTWE.---........DTGQGPAN..SCPQIQKLWSIGRWLPLGP.--A.EDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQIL.............
F8VW47_HUMAN/178-335             ...MYASFGFVDLEEMNPL....SISCFFCGRFSISlSH.EVSIFRYCAPTAYTASRFPRyLYKKMRWHLEATP.E.APGRGQD---..........SLVDYYFLCYRDTWE.---........DTGQSPAN..SCPQIQKLWSIGRWVPLGP.--A.EDDLYSWILCPQPLGDYQQLLTIGFEEPTPTLATDLLVQIL.............
H2NXS5_PONAB/92-249              ...MYASFGFVDLEETNPL....SISCFFCGRFSISlSH.EVSIFRYCAPTAYTASRFPRyLYKKMRWHLEATP.E.APGHGQD---..........SLVDYYFLCYRDTWE.---........DTGQSPAN..SCPQIQKLWSIGRWVPLGP.--A.EDDLYSWILCPQPLGDYQQLLTIGFEEPTPTLATDLLVQIL.............
G1SVB1_RABIT/92-250              ...MYASFGLVDMEETDPL...sSISSFFCGRFSLSpTH.EVSIFRYCAPAAYTATRFPRyLYKKMRWNLETTL.E.PSGQGQH---..........SRVDYYFLCYRDTWE.---........DSGKTLAN..SCPQIQKLWSIGRWVPLGP.--A.EDDLYSWILCPQPPGDYQQLLTIGFEEPSHMLATDLLVQIL.............
A2BGV4_DANRE/95-239              ...LFASFSFCSLEESDPL....SVSHFSIGQCQID.NM.KVSIFRYCCPTPFLASSLTG.LYKRMRWNVEREI.E.EEGDGKTYDS..........--AEFYFLCCEDVIE.AADdqnedrssEGESTETD..SESKVSRIWSIGRWVQTYP.DPN.TEDIIDWVLCSLPCGQ-------------------------.............
F6VPD7_HORSE/92-253              ...MYASFGFSGSTLITPLpspaSISCFFCGRFAISpSH.EVSIFRYCAPAAYTASRFPRyLYKKMRWNLETTP.E.PSVQGQD---..........SYVDYYFLCYRDTWE.---........DTGSSPAN..SCPQIQKLWSIGRWVPLEP.--A.EDDLYSWILCPQPLGDYQQLLTIGFEEPSHTLATDLLVQML.............
G1M3C2_AILME/92-249              ...MYASFGFVDLEETDPL....SISCFFCGRFSISpSH.EVSIFRYCAPAAYTASRFPRyLYKKMRWNLETTP.E.PSGRGQD---..........SHVDYYFLCYRDTWE.---........DTGKSPAN..SCPQIQKLWSIGRWVPLGP.--D.EDDLYSWILCPQPPGDYQQLLTIGFEEPSHMLATDLLVQIL.............
Q4RZS2_TETNG/1-161               mft---------------K....SVSHFAIGQSDIR.GL.RLTTFVYCKPAPYLAQGNTG.LYKCMRWNVDLPG.N.QAEASEAWDGksedldmenlSVTEYYFLCYEETRH.PAK........EAIPLGLD..VGGEAVRKWSIGLWRHSEP.QTT.TDDVVDWLLCPVPSASFKKMLLLD-EEPSSWYATDLLVQLL.............
G3Q6L9_GASAC/95-255              ..t-YASCNVLCLDETNPI....SLSHFCIGQSQLG.AL.RVKAFRYCKPTPYLARLDTG.LYKRMRWNVERHR.D.EYGEGQIVCD..........--TEYYFLCYEDIPNrHAD........AGRDHDGV..SHSNVVRMWSIGQWQQVTP.--E.TDDIDDWVLCEVPQANYHKLLYFGSEEPSSCRATEHLQQLL.............
G3QIT6_GORGO/92-249              ...MYASFGFVDLEEMNPL....SISCFFCGRFSISlSH.EVSIFRYCAPTAYTASRFPRyLYKKMRWHLEATP.E.APGRGQD---..........SLVDYYFLCYRDTWE.---........DTGQSPAN..SCPQIQKLWSIGRWVPLGP.--A.EDDLYSWILCPQPLGDYQQLLTIGFEEPTPTLATDLLVQIL.............
F1Q8A6_DANRE/162-331             ...LFASFSFCSLEESDPL....SVSHFSIGQCQID.NM.KVSIFRYCCPTPFLASSLTG.LYKRMRWNVEREI.E.EEGDGKTYDS..........--AEFYFLCCEDVIE.AADdqnedrssEGESTETD..SESKVSRIWSIGRWVQTYP.DPN.TEDIIDWVLCSLPCGQYKQLLCLGNEEPSSCTATDCLLGAL.............
H0VQ02_CAVPO/92-249              ...MYASFGFVELEETDPL....SISSFFCGRFSINpFQ.EVSIFRYCAPAAYTASRQPRyLYKKMRWNLETTP.K.PSSQGQH---..........ARVDYYFLCYRDTWE.---........DTGQSPAT..SCPQIQKLWSIGRWVPLGP.--E.DDDLYSWVSCPQPPGDYQQLLTIGFEEPSHVLATDLLLQV-r............
B7ZWF8_MOUSE/91-248              ...MYASFGFVDLEETNPL....SISCFFCGRFSISpSH.DVSIFRYCTPAAYTASHFPRyLYKKMRWNLETTT.E.ASSQGAD---..........SHVDYYFLCYRDTWE.---........DAGQGPAN..SCPQIQKLWSIGRWMPLGP.--A.EDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQIL.............
H0WKS6_OTOGA/198-233             .pr----------------....-------------.--.--------------------.-------------.-.----------..........---------------.---........--------..-------------------.---.-------ILCPQPPGDYQQLLTIGFEEPSHILATDLLVQIL.............
G7NLZ2_MACMU/92-249              ...MYASFGFVDLEETNPL....SISCFFCGRFSISlSH.EISIFRYCAPTAYTASRFPRyLYKKMRWHLEATP.E.APGRGQD---..........SLVDYYFLCYRDTWE.---........DTGQSPAN..SCPQIQKLWSIGRWVPLGP.--A.EDDLYSWILCPQPLGDYQQLLTIGFEEPTPMLATDLLVQIL.............
D4A283_RAT/120-277               ...MYASFGFVDLEETNPL....SISCFFCGRFSISpSH.DVSIFRYCTPAAYTASHFPRyLYKKMRWNLETTT.E.ASSQGAD---..........AHVDYYFLCYRDTWE.---........DAGQGPAN..SCPQIQKLWSIGRWMPLGP.--A.EDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQIL.............
H2QFJ9_PANTR/178-335             ...MYASFGFVDLEEMNPL....SISCFFCGRFSISlSH.EVSIFRYCAPTAYTASRFPRyLYKKMRWHLEATP.E.APGRGQD---..........SLVDYYFLCYRDTWE.---........DTGQSPAN..SCPQIQKLWSIGRWVPLGP.--A.EDDLYSWILCPQPLGDYQQLLTIGFEEPTPTLATDLLVQIL.............
G5BYT6_HETGA/92-249              ...MYASCGFVELEETNPL....SISCFFCGRFSISpFQ.EVSIFRYCTPAAYTASRQPRyLYKKMRWNLETTT.K.PSSQGQN---..........SHVDYYFLCYRDIWE.---........DTGQSPAN..SCPQIQKLWSIGRWVSLGP.--A.DDDLYSWVSCPQPPGDYQQLLIIGFEEPSHMLATDLLLQVL.............
F7G4Z8_MONDO/92-252              ...MYASFGFVVLEETDPL....SVSCFFCGKFSLGpSH.QVSVFRYCSPAPYTAGRLPRyLYKKMRWNLEASP.E.TSNRGHG---..........PHVEYYFLCYRDTWE.---........DTGKSPAN..SCAQIQKLWSIGRWVPLGPgQDG.SSDIYSWILCPQPPGEYQQLLTIGFEEPSHTLATDLLVQIL.............
G3W612_SARHA/1-152               ...MYASFGFVVLEETDPL....SVSCFFCGKFSLGpSH.QVSVFRYCSPAPYTAGRLPRyLYKKMRWNLEASP.E.TNNRGHG---..........PHVEYYFLCYRDTWE.---........DTGKSPAN..SCAQIQKLWSIGRWVPLGPgQDG.SSDIYSWILCPQPPGEYQQLLTIGFX---------------xxxxxx.......
Q4TCQ0_TETNG/1-141               ...----------------....-VSHFAIGQSDIR.GL.RLTTFVYCKPAPYLAQGNTG.LYKCMRWNVDLPG.N.QAEATNTLFS..........-----YFLCYEETRH.PAK........EAIPLGLD..VGGEAVRKWSIGLWRHSEP.QTT.TDDVVDWLLCPVPSASFKKMLLLD-EEPSSWYATDLLVQLL.............
G1Q085_MYOLU/92-249              ...MYASFGFVELEETDPL....SISCFFCGRFSISpSH.EVSIFRYCAPAAYTTSRFPRyLYKKMRWNLETTP.D.PSSRGQD---..........SHVDYYFLCYRDTWE.---........DTGKSPAN..SCPQIQKLWSIGRWVPLGP.--A.EDDLYSWILCPQPSGDYQQLLTIGFEEPSHMLATDLLVQIL.............
H0WKS6_OTOGA/92-194              ...MYASFGFVNLEETDPL....SISCFFCGRFSISpSH.EVSIFRYCAPAAYTASRFPRyLYKKMRWNLETIP.G.PSGRGQD---..........SHVEYFFCCSAITSH.S--........--------..-------------------.---.-----------------------------------------rggtpeglsvpap
F6UZF9_MOUSE/121-278             ...MYASFGFVDLEETNPL....SISCFFCGRFSISpSH.DVSIFRYCTPAAYTASHFPRyLYKKMRWNLETTT.E.ASSQGAD---..........SHVDYYFLCYRDTWE.---........DAGQGPAN..SCPQIQKLWSIGRWMPLGP.--A.EDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQIL.............
G3UZX3_MOUSE/120-277             ...MYASFGFVDLEETNPL....SISCFFCGRFSISpSH.DVSIFRYCTPAAYTASHFPRyLYKKMRWNLETTT.E.ASSQGAD---..........SHVDYYFLCYRDTWE.---........DAGQGPAN..SCPQIQKLWSIGRWMPLGP.--A.EDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQIL.............
B2RVM9_MOUSE/92-249              ...MYASFGFVDLEETNPL....SISCFFCGRFSISpSH.DVSIFRYCTPAAYTASHFPRyLYKKMRWNLETTT.E.ASSQGAD---..........SHVDYYFLCYRDTWE.---........DAGQGPAN..SCPQIQKLWSIGRWMPLGP.--A.EDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQIL.............
F7I3C5_CALJA/114-271             ...MYASFGFVDLEETNPL....SISCFFCGRFSISmSH.EVSIFRYCAPAAYTASRFPRyLYKKMRWHLETIP.E.APGRGQD---..........TLVDYYFLCYRDTWE.---........DTGQTPAN..PFPQIQKLWSIGRWVPLGP.--A.EDDLYSWILCPQPLGDYQQLLTIGFEEPSPMLATDLLVQIL.............
E1BDZ6_BOVIN/92-249              ...MYASFGFVNLEETDPL....SISCFFCGRFTISpSH.EVSIFRYCAPAAYTASRFPRyLYKKMRWNLETTP.E.PSSREQD---..........SHVDYYFLCYRDTWE.---........DTGKSPAN..SCPQIQKLWSIGRWMPLGP.--A.EDDLYSWILCPQPPGDYQQLLTIGFEEPSHMLATDLLVQIL.............
G1TF94_RABIT/92-250              ...MYASFGLVDMEETDPL...sSISSFFCGRFSLSpTH.EVSIFRYCAPAAYTATRFPRyLYKKMRWNLETTL.E.PSGQGQH---..........SRVDYYFLCYRDTWE.---........DSGKTLAN..SCPQIQKLWSIGRWVPLGP.--A.EDDLYSWILCPQPPGDYQQLLTIGFEEPSHMLATDLLVQIL.............
G3TMK5_LOXAF/92-249              ...MYASFGLVDLEETDPL....SISCFFCGRFSISpSH.EVSIFRYCAPAAYTASRFPRyLYKKMRWNLETTP.E.PSSWGQD---..........SHVDYYFLCYRDTWE.---........DTGKSPVN..SCAQIQKLWSIGRWVPLGP.--V.DDDLYSWILCPQPPGDYQQLLTIGFEEPSHMLATDLLVQIL.............
G1RSK2_NOMLE/92-249              ...MYASFGFVDLEETNPL....SISCFFCGRFSISlSH.EVSIFRYCAPTAYTASRFPRyLYKKMRWHLEATP.E.APGRGQD---..........SLVDYYFLCYRDTWE.---........DTGQSPAN..SCPQIQKLWSIGRWVPLGP.--A.EDDLYSWILCPQPLGDYQQLLTIGFQEPTPTLATDLLVQIL.............
#=GC seq_cons                    ...MYASFGFVsLEETsPL....SISCFFCGRFSIS.SH.-VSIFRYCsPsAYTAS+FPRYLYKKMRWNLEsTs.E.ssupGp-.............ShVDYYFLCYRDTWE............DsGpoPAN..SCPQIQKLWSIGRWVPLGP...s.-DDLhSWILCPQPsGDYQQLLTIGFEEPSphLATDLLVQlL.............
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