GenomeNet

Database: Pfam
Entry: DUF3652
LinkDB: DUF3652
Original site: DUF3652 
#=GF ID   DUF3652
#=GF AC   PF12372.7
#=GF DE   Huntingtin protein region 
#=GF AU   Gavin OL
#=GF SE   Prosite
#=GF GA   25.50 25.50;
#=GF TC   26.10 26.20;
#=GF NC   24.10 25.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   7647777
#=GF RT   Cellular localization of the Huntington's disease protein and
#=GF RT   discrimination of the normal and mutated form.
#=GF RA   Trottier Y, Devys D, Imbert G, Saudou F, An I, Lutz Y, Weber C,
#=GF RA   Agid Y, Hirsch EC, Mandel JL;
#=GF RL   Nat Genet. 1995;10:104-110.
#=GF DR   INTERPRO; IPR024613;
#=GF CC   This domain family is found in eukaryotes, and is approximately
#=GF CC   40 amino acids in length. The family is found in association
#=GF CC   with Pfam:PF02985. This family is in the middle region of the
#=GF CC   Huntingtin protein associated with Huntington's disease. The
#=GF CC   protein is of unknown function, however it is known that a
#=GF CC   polyglutamine (CAG) repeat in the gene coding for it results in
#=GF CC   the development of Huntington's disease.
#=GF SQ   150
#=GS A0A091PF02_LEPDC/491-531    AC A0A091PF02.1
#=GS G3X9H5_MOUSE/1494-1534      AC G3X9H5.1
#=GS L9KIK8_TUPCH/1746-1786      AC L9KIK8.1
#=GS G1KE86_ANOCA/1480-1520      AC G1KE86.2
#=GS H2QP49_PANTR/1485-1525      AC H2QP49.1
#=GS A0A154P7E3_9HYME/1267-1307  AC A0A154P7E3.1
#=GS A0A0L8FHF7_OCTBM/1396-1436  AC A0A0L8FHF7.1
#=GS E2AM71_CAMFO/1290-1330      AC E2AM71.1
#=GS A0A093EYJ3_TYTAL/767-807    AC A0A093EYJ3.1
#=GS A0A091RJ36_9GRUI/1490-1530  AC A0A091RJ36.1
#=GS H0V9L0_CAVPO/1518-1558      AC H0V9L0.1
#=GS T1F3E5_HELRO/1369-1409      AC T1F3E5.1
#=GS A0A096ML42_PAPAN/1-26       AC A0A096ML42.1
#=GS F6VQZ3_MACMU/1520-1560      AC F6VQZ3.1
#=GS V8NHE3_OPHHA/638-678        AC V8NHE3.1
#=GS W5KSK8_ASTMX/1558-1598      AC W5KSK8.1
#=GS U4UQK1_DENPD/175-215        AC U4UQK1.1
#=GS A0A093G0H8_PICPB/1489-1529  AC A0A093G0H8.1
#=GS A0A093FNQ6_GAVST/1057-1097  AC A0A093FNQ6.1
#=GS G1M886_AILME/1519-1559      AC G1M886.1
#=GS G3Q320_GASAC/1505-1545      AC G3Q320.1
#=GS G3TAJ5_LOXAF/1499-1539      AC G3TAJ5.1
#=GS H2ZNB5_CIOSA/1428-1468      AC H2ZNB5.1
#=GS G3W1T8_SARHA/1432-1472      AC G3W1T8.1
#=GS V4AN43_LOTGI/1383-1423      AC V4AN43.1
#=GS A0A026WC84_CERBI/1289-1329  AC A0A026WC84.1
#=GS D6X048_TRICA/1236-1276      AC D6X048.2
#=GS A0A094N246_9AVES/1435-1475  AC A0A094N246.1
#=GS A0A091P956_APAVI/305-345    AC A0A091P956.1
#=GS G1QHE5_NOMLE/1482-1522      AC G1QHE5.1
#=GS A0A087VI63_BALRE/1435-1475  AC A0A087VI63.1
#=GS H3AAE1_LATCH/1489-1529      AC H3AAE1.1
#=GS B5DYE6_DROPS/2808-2850      AC B5DYE6.2
#=GS A0A194QHZ9_PAPXU/1412-1444  AC A0A194QHZ9.1
#=GS A0A0D9RTK1_CHLSB/1504-1544  AC A0A0D9RTK1.1
#=GS A0A162PA16_9CRUS/1454-1494  AC A0A162PA16.1
#=GS A0A0A0AVV7_CHAVO/1435-1475  AC A0A0A0AVV7.1
#=GS W5MWN7_LEPOC/1430-1470      AC W5MWN7.1
#=GS B4HZ09_DROSE/2709-2751      AC B4HZ09.1
#=GS K1RMW1_CRAGI/1371-1411      AC K1RMW1.1
#=GS A0A094K8B3_ANTCR/1435-1475  AC A0A094K8B3.1
#=GS A0A0N0BHX5_9HYME/1279-1319  AC A0A0N0BHX5.1
#=GS I3ME89_ICTTR/1487-1527      AC I3ME89.1
#=GS A7RGU1_NEMVE/1541-1566      AC A7RGU1.1
#=GS G3GWA8_CRIGR/1300-1340      AC G3GWA8.1
#=GS B4N8Q2_DROWI/2706-2747      AC B4N8Q2.2
#=GS A0A091TMD9_PHALP/1492-1532  AC A0A091TMD9.1
#=GS H2SJ19_TAKRU/916-956        AC H2SJ19.1
#=GS E4X2T0_OIKDI/1014-1053      AC E4X2T0.1
#=GS G3RJY1_GORGO/1351-1391      AC G3RJY1.1
#=GS G3UGQ6_LOXAF/1446-1486      AC G3UGQ6.1
#=GS T1IW53_STRMM/1319-1359      AC T1IW53.1
#=GS I6L6Y1_TAKRU/1508-1548      AC I6L6Y1.1
#=GS F7C6C4_MONDO/1506-1546      AC F7C6C4.2
#=GS M7BEE4_CHEMY/1313-1353      AC M7BEE4.1
#=GS A0A087UJL3_9ARAC/739-779    AC A0A087UJL3.1
#=GS W5PXJ0_SHEEP/1480-1520      AC W5PXJ0.1
#=GS E1B8E7_BOVIN/1509-1549      AC E1B8E7.1
#=GS A0A0R4IG01_DANRE/1487-1527  AC A0A0R4IG01.1
#=GS A0A093C8D7_9AVES/305-345    AC A0A093C8D7.1
#=GS A0A151PA91_ALLMI/1468-1508  AC A0A151PA91.1
#=GS G3Q318_GASAC/1511-1551      AC G3Q318.1
#=GS K7ECW3_ORNAN/60-100         AC K7ECW3.1
#=GS A0A093L5K1_EURHL/1434-1474  AC A0A093L5K1.1
#=GS K7J8T7_NASVI/1356-1396      AC K7J8T7.1
#=GS A0A0L7RHN1_9HYME/1283-1323  AC A0A0L7RHN1.1
#=GS A0A158P153_ATTCE/1286-1326  AC A0A158P153.1
#=GS G3V9P7_RAT/1494-1534        AC G3V9P7.1
#=GS E2C517_HARSA/1283-1323      AC E2C517.1
#=GS E9GU71_DAPPU/1093-1133      AC E9GU71.1
#=GS F1P7Y7_CANLF/1503-1543      AC F1P7Y7.2
#=GS H2MI92_ORYLA/1506-1546      AC H2MI92.1
#=GS F1S8N5_PIG/1513-1553        AC F1S8N5.2
#=GS H2SJ18_TAKRU/1518-1558      AC H2SJ18.1
#=GS G7NVR7_MACFA/1425-1465      AC G7NVR7.1
#=GS U3KPH8_RABIT/1442-1482      AC U3KPH8.1
#=GS A0A151X8Y5_9HYME/1286-1326  AC A0A151X8Y5.1
#=GS G1NJV8_MELGA/1450-1490      AC G1NJV8.2
#=GS A0A0R3NKP7_DROPS/2808-2850  AC A0A0R3NKP7.1
#=GS A0A0R3NEZ3_DROPS/1185-1227  AC A0A0R3NEZ3.1
#=GS H0ZJI1_TAEGU/933-973        AC H0ZJI1.1
#=GS T1KK12_TETUR/1348-1388      AC T1KK12.1
#=GS F6Z217_XENTR/1506-1546      AC F6Z217.1
#=GS A0A091D3Y8_FUKDA/1449-1489  AC A0A091D3Y8.1
#=GS A0A091QM17_MERNU/613-653    AC A0A091QM17.1
#=GS S7QAG9_MYOBR/514-539        AC S7QAG9.1
#=GS A0A093QW17_PHACA/1435-1475  AC A0A093QW17.1
#=GS H2ZNB7_CIOSA/1433-1473      AC H2ZNB7.1
#=GS H3C3K9_TETNG/916-956        AC H3C3K9.1
#=GS A0A093HWB3_STRCA/1500-1540  AC A0A093HWB3.1
#=GS HD_HUMAN/1513-1553          AC P42858.2
#=GS A0A091GCR0_9AVES/1435-1475  AC A0A091GCR0.1
#=GS U3K591_FICAL/1525-1565      AC U3K591.1
#=GS F6ZCK5_CALJA/1525-1565      AC F6ZCK5.1
#=GS Q9V3N4_DROME/2717-2759      AC Q9V3N4.1
#=GS A0A0N8K0Q6_9TELE/1419-1459  AC A0A0N8K0Q6.1
#=GS H9IYB8_BOMMO/522-557        AC H9IYB8.1
#=GS F6XPL5_CALJA/1503-1543      AC F6XPL5.1
#=GS S9Y008_CAMFR/1349-1398      AC S9Y008.1
#=GS A0A0Q3QQG2_AMAAE/1451-1491  AC A0A0Q3QQG2.1
#=GS H3D3C4_TETNG/1480-1520      AC H3D3C4.1
#=GS U3IJW4_ANAPL/1483-1523      AC U3IJW4.1
#=GS HD_RAT/1484-1524            AC P51111.1
#=GS A0A0L8FHD1_OCTBM/1396-1436  AC A0A0L8FHD1.1
#=GS H0WWN4_OTOGA/1477-1517      AC H0WWN4.1
#=GS B4GP12_DROPE/2793-2835      AC B4GP12.1
#=GS A0A067RBZ0_ZOONE/1399-1439  AC A0A067RBZ0.1
#=GS E1BZK0_CHICK/1451-1491      AC E1BZK0.2
#=GS B3S350_TRIAD/963-1003       AC B3S350.1
#=GS B4QYS8_DROSI/3353-3395      AC B4QYS8.1
#=GS I3KRU4_ORENI/1495-1535      AC I3KRU4.1
#=GS F4W9A2_ACREC/1286-1326      AC F4W9A2.1
#=GS J9KJG1_ACYPI/1188-1225      AC J9KJG1.2
#=GS A0A091VMN8_NIPNI/1499-1539  AC A0A091VMN8.1
#=GS E9J746_SOLIN/1260-1300      AC E9J746.1
#=GS C3ZGJ9_BRAFL/1378-1418      AC C3ZGJ9.1
#=GS A0A091II49_CALAN/1463-1503  AC A0A091II49.1
#=GS HD_MOUSE/1493-1533          AC P42859.2
#=GS A0A088AQ61_APIME/1287-1327  AC A0A088AQ61.1
#=GS B3LV94_DROAN/2713-2755      AC B3LV94.2
#=GS A0A091WJE7_OPIHO/1428-1468  AC A0A091WJE7.1
#=GS B4JXS7_DROGR/2689-2730      AC B4JXS7.1
#=GS E0W1H5_PEDHC/1220-1260      AC E0W1H5.1
#=GS A0A151P9C0_ALLMI/1452-1492  AC A0A151P9C0.1
#=GS A0A087Y8G5_POEFO/1442-1483  AC A0A087Y8G5.1
#=GS A0A091MSN2_9PASS/1435-1475  AC A0A091MSN2.1
#=GS K7G9G4_PELSI/1468-1508      AC K7G9G4.1
#=GS A0A099Z4W2_TINGU/1431-1471  AC A0A099Z4W2.1
#=GS G1SY00_RABIT/1474-1514      AC G1SY00.1
#=GS A0A0J7NRM2_LASNI/1199-1239  AC A0A0J7NRM2.1
#=GS M3W2I3_FELCA/1431-1471      AC M3W2I3.1
#=GS M3YH08_MUSPF/1391-1431      AC M3YH08.1
#=GS L5M3N0_MYODS/1577-1617      AC L5M3N0.1
#=GS W4Y8K8_STRPU/695-720        AC W4Y8K8.1
#=GS G3RMC4_GORGO/1431-1471      AC G3RMC4.1
#=GS A0A091L3I6_CATAU/1225-1265  AC A0A091L3I6.1
#=GS G1P179_MYOLU/1503-1543      AC G1P179.1
#=GS H2ZNB8_CIOSA/1354-1394      AC H2ZNB8.1
#=GS M3ZTD8_XIPMA/1509-1549      AC M3ZTD8.1
#=GS H2PCR6_PONAB/1503-1543      AC H2PCR6.1
#=GS L5K4U1_PTEAL/1583-1623      AC L5K4U1.1
#=GS A0A091GWG1_BUCRH/1490-1530  AC A0A091GWG1.1
#=GS HD_TAKRU/1508-1548          AC P51112.1
#=GS B7ZDE9_DANRE/1487-1527      AC B7ZDE9.1
#=GS A0A091U1H3_PHORB/1430-1470  AC A0A091U1H3.1
#=GS A0A091LPU0_CARIC/1506-1546  AC A0A091LPU0.1
#=GS F7BQH8_HORSE/1432-1472      AC F7BQH8.1
#=GS A0A091F031_CORBR/1435-1475  AC A0A091F031.1
#=GS G5BZF2_HETGA/1386-1426      AC G5BZF2.1
#=GS I1GHU9_AMPQE/1141-1180      AC I1GHU9.1
A0A091PF02_LEPDC/491-531               ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
G3X9H5_MOUSE/1494-1534                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
L9KIK8_TUPCH/1746-1786                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
G1KE86_ANOCA/1480-1520                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFILR........
H2QP49_PANTR/1485-1525                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A154P7E3_9HYME/1267-1307             .t-IITVPNIIQLCDGLMASGQPALTH.C.........IPAI.....APVVEDVFLIR........
A0A0L8FHF7_OCTBM/1396-1436             ..PIIGIPKIIQLCDGIMASGLQPTTH.A.........IPAL.....QPIVYDLFLLR........
E2AM71_CAMFO/1290-1330                 ..AIIGIPKIIQLCDGLMASGQPAITH.C.........IPAL.....APVIEDIFLIR........
A0A093EYJ3_TYTAL/767-807               ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A091RJ36_9GRUI/1490-1530             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
H0V9L0_CAVPO/1518-1558                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
T1F3E5_HELRO/1369-1409                 .p-VITIPKIIQLCDGIMASGLNPVKF.C.........IPSL.....HYVTKSLFA--lk......
A0A096ML42_PAPAN/1-26                  ..---------------MASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
F6VQZ3_MACMU/1520-1560                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
V8NHE3_OPHHA/638-678                   ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFILR........
W5KSK8_ASTMX/1558-1598                 ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
U4UQK1_DENPD/175-215                   ..SIVDVPKIIQLCDGLMASGQDPETH.C.........IPSL.....KPIVEDVFLFR........
A0A093G0H8_PICPB/1489-1529             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A093FNQ6_GAVST/1057-1097             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
G1M886_AILME/1519-1559                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
G3Q320_GASAC/1505-1545                 ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
G3TAJ5_LOXAF/1499-1539                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
H2ZNB5_CIOSA/1428-1468                 ..SVITMSKIIQLCDGLMASEQGSASH.V.........IPAM.....QPITHDIFVVR........
G3W1T8_SARHA/1432-1472                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
V4AN43_LOTGI/1383-1423                 .v-IIDMNGVIHRCDGIMASGLQPTKH.A.........IPAL.....RPIVYDLFLLR........
A0A026WC84_CERBI/1289-1329             ..AIIGIPKIIQLCDGLMASGQPAISH.C.........IPAL.....APVIEDIFLIR........
D6X048_TRICA/1236-1276                 ..SIITVPKIIHLCDGLMASEQSPLTH.C.........IPAL.....EPIVENIFLTR........
A0A094N246_9AVES/1435-1475             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A091P956_APAVI/305-345               ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
G1QHE5_NOMLE/1482-1522                 ..QIIGIPKIIQLCDGIMASGRKAVTH.V.........CPSL.....RAWWHDL----gslq....
A0A087VI63_BALRE/1435-1475             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
H3AAE1_LATCH/1489-1529                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
B5DYE6_DROPS/2808-2850                 ..ALLQQPRVW---RDLNASTDAALRC.E.........LLEVlchsaRCMLQETIFYQ........
A0A194QHZ9_PAPXU/1412-1444             ..QLIEIPKLIQLCDGLMASGAH--AE.C.........I---.....-----------aglepvav
A0A0D9RTK1_CHLSB/1504-1544             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A162PA16_9CRUS/1454-1494             .t-IISVPRIMQLAGGLMATGKDAELH.V.........LPTL.....RPMVEDLFLS-r.......
A0A0A0AVV7_CHAVO/1435-1475             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
W5MWN7_LEPOC/1430-1470                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
B4HZ09_DROSE/2709-2751                 ..ALLQQPRVW---RELNASLDHSLRC.E.........LLDLldsvaRCILQDTIFYR........
K1RMW1_CRAGI/1371-1411                 ..SIIGMPKIIQLCDGIMASGLQPVSH.A.........IPAL.....RPVVFDLFLLR........
A0A094K8B3_ANTCR/1435-1475             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A0N0BHX5_9HYME/1279-1319             ..AIIGIPKIIQLCDGLMASGQPELTH.C.........IPAL.....APVVEDVFLIR........
I3ME89_ICTTR/1487-1527                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A7RGU1_NEMVE/1541-1566                 ..AIVGMAKVIQLCDGIMASGQSAKTH.-.........----.....-----------g.......
G3GWA8_CRIGR/1300-1340                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
B4N8Q2_DROWI/2706-2747                 ..ALLQHPRIW---REVNASTT-GVRS.E.........LLEVltmtgRCLLQDTIFYQ........
A0A091TMD9_PHALP/1492-1532             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
H2SJ19_TAKRU/916-956                   ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
E4X2T0_OIKDI/1014-1053                 fv---TKSEVINLCNSLNAAGLSAETH.A.........IPAL.....SPIVDDIFS--le......
G3RJY1_GORGO/1351-1391                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
G3UGQ6_LOXAF/1446-1486                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
T1IW53_STRMM/1319-1359                 .l-IIGVPKIIQLCDGIMASGQPPTTH.A.........IPCL.....IPIVEDLFLMR........
I6L6Y1_TAKRU/1508-1548                 ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
F7C6C4_MONDO/1506-1546                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
M7BEE4_CHEMY/1313-1353                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A087UJL3_9ARAC/739-779               ..PIISVPKILQLCDSLIASGQPPDKY.V.........VRAL.....QPVIEDLFLI-k.......
W5PXJ0_SHEEP/1480-1520                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
E1B8E7_BOVIN/1509-1549                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A0R4IG01_DANRE/1487-1527             ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A093C8D7_9AVES/305-345               ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A151PA91_ALLMI/1468-1508             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
G3Q318_GASAC/1511-1551                 ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
K7ECW3_ORNAN/60-100                    ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A093L5K1_EURHL/1434-1474             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
K7J8T7_NASVI/1356-1396                 .l-IIGVPKIIQLCDGLMASGQPPLTH.C.........IPAL.....VPVVEEMFLAR........
A0A0L7RHN1_9HYME/1283-1323             ..AIIGIPKIIQLCDGLMASGQPALTH.C.........IPAL.....APVVEDVFLIR........
A0A158P153_ATTCE/1286-1326             ..AIIGIPKIIQLCDGLMASGQPAISH.C.........IPAL.....APVIEDIFLIR........
G3V9P7_RAT/1494-1534                   ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
E2C517_HARSA/1283-1323                 ..AIIGIPKIIQLCDGLMASGQPAISH.C.........IPAL.....APVIEDIFLIR........
E9GU71_DAPPU/1093-1133                 .t-IISVPRIMQLAGGLMATGKDAELH.V.........LPTL.....QPMVEDLFLS-r.......
F1P7Y7_CANLF/1503-1543                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
H2MI92_ORYLA/1506-1546                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFILR........
F1S8N5_PIG/1513-1553                   ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
H2SJ18_TAKRU/1518-1558                 ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
G7NVR7_MACFA/1425-1465                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
U3KPH8_RABIT/1442-1482                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A151X8Y5_9HYME/1286-1326             ..AIIGIPKIIQLCDGLMASGQPAISH.C.........IPAL.....APVIEDIFLIR........
G1NJV8_MELGA/1450-1490                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A0R3NKP7_DROPS/2808-2850             ..ALLQQPRVW---RDLNASTDAALRC.E.........LLEVlchsaRCMLQETIFYQ........
A0A0R3NEZ3_DROPS/1185-1227             ..ALLQQPRVW---RDLNASTDAALRC.E.........LLEVlchsaRCMLQETIFYQ........
H0ZJI1_TAEGU/933-973                   ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
T1KK12_TETUR/1348-1388                 ..PIITVPKIIQMCDDLMASDQPPVFY.A.........LPAL.....RQIVEDLMLYR........
F6Z217_XENTR/1506-1546                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A091D3Y8_FUKDA/1449-1489             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A091QM17_MERNU/613-653               ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
S7QAG9_MYOBR/514-539                   ..QIIGIPKIIQLCDGIMASGRKAVTH.-.........----.....-----------g.......
A0A093QW17_PHACA/1435-1475             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
H2ZNB7_CIOSA/1433-1473                 ..SVITMSKIIQLCDGLMASEQGSASH.V.........IPAM.....QPITHDIFVVR........
H3C3K9_TETNG/916-956                   ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A093HWB3_STRCA/1500-1540             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
HD_HUMAN/1513-1553                     ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A091GCR0_9AVES/1435-1475             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
U3K591_FICAL/1525-1565                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
F6ZCK5_CALJA/1525-1565                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
Q9V3N4_DROME/2717-2759                 .t-LLQQPRVW---RELNASSDPSLRC.E.........LLDLldsvaRCILQDTIFYR........
A0A0N8K0Q6_9TELE/1419-1459             ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
H9IYB8_BOMMO/522-557                   .k-IIEIPKLIQLCDGLMASGA--HAE.C.........IAGL.....EPV--------avkvf...
F6XPL5_CALJA/1503-1543                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
S9Y008_CAMFR/1349-1398                 ..QIIGIPKIIQLCDGVMASGRKGLRR.ThrakcglgpIPAL.....RPIVHDLFVLR........
A0A0Q3QQG2_AMAAE/1451-1491             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
H3D3C4_TETNG/1480-1520                 ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
U3IJW4_ANAPL/1483-1523                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
HD_RAT/1484-1524                       ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A0L8FHD1_OCTBM/1396-1436             ..PIIGIPKIIQLCDGIMASGLQPTTH.A.........IPAL.....QPIVYDLFLLR........
H0WWN4_OTOGA/1477-1517                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
B4GP12_DROPE/2793-2835                 ..ALLQQPRVW---RDLNASTDAALRC.E.........LLEVlchsaRCMLQETIFYQ........
A0A067RBZ0_ZOONE/1399-1439             ..SIIGVPKVIQLCDGLMASGQSPVTH.C.........IPAL.....VPVVEDVFLIR........
E1BZK0_CHICK/1451-1491                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
B3S350_TRIAD/963-1003                  .p-IVGIPRILQLSDGIMASGQLAPAH.V.........IPAF.....RPVVFDLFNVR........
B4QYS8_DROSI/3353-3395                 ..ALLQQPRVW---RELNASLNPSLRC.E.........LLDLldsvaRCILQDTIFYR........
I3KRU4_ORENI/1495-1535                 ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
F4W9A2_ACREC/1286-1326                 ..AIIGIPKIIQLCDGLMASGQPAISH.C.........IPAL.....APVIEDIFLIR........
J9KJG1_ACYPI/1188-1225                 .i----IPEAIHLCDGLMASGYPPELY.C.........IPAI.....LPIVEYVY---vlk.....
A0A091VMN8_NIPNI/1499-1539             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
E9J746_SOLIN/1260-1300                 .v-IIGIPKIIQLCDGLMASGQPAISH.C.........IPAL.....APVIEDIFLIR........
C3ZGJ9_BRAFL/1378-1418                 ..SIIVMPRIIQLCDGVMASGQKATNH.A.........IPAL.....QPIVHDLFVLR........
A0A091II49_CALAN/1463-1503             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
HD_MOUSE/1493-1533                     ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A088AQ61_APIME/1287-1327             ..AIIGIPKIIQLCDGLMASGQPALTY.C.........IPAL.....APVVEDVFLIR........
B3LV94_DROAN/2713-2755                 ..ALLLQPRVW---RDLNARLDPGPRC.D.........LLELldrvsGCILQDTIFYQ........
A0A091WJE7_OPIHO/1428-1468             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
B4JXS7_DROGR/2689-2730                 ..AMLQQPRIW---GAINSSTD-ALRV.E.........LLEVpvlaaRHMLQDTIFY-h.......
E0W1H5_PEDHC/1220-1260                 ..PIISMPKILQLCDDLMASDQPVQTH.C.........LPAL.....IPVVEDVFLIR........
A0A151P9C0_ALLMI/1452-1492             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A087Y8G5_POEFO/1442-1483             ..QIISIPKIIQLCDGIMASGRKAVTHaA.........IPAL.....QPIVYDLFVLR........
A0A091MSN2_9PASS/1435-1475             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
K7G9G4_PELSI/1468-1508                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A099Z4W2_TINGU/1431-1471             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
G1SY00_RABIT/1474-1514                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A0J7NRM2_LASNI/1199-1239             ..AIIGIPKIIQLCDGLMASGQPAITH.C.........IPAL.....APVIEDIFLIR........
M3W2I3_FELCA/1431-1471                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
M3YH08_MUSPF/1391-1431                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
L5M3N0_MYODS/1577-1617                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
W4Y8K8_STRPU/695-720                   .p-VIAMPKIIQLCDGIMASGQQASTH.-.........----.....-----------s.......
G3RMC4_GORGO/1431-1471                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A091L3I6_CATAU/1225-1265             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
G1P179_MYOLU/1503-1543                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
H2ZNB8_CIOSA/1354-1394                 ..SVITMSKIIQLCDGLMASEQGSASH.V.........IPAM.....QPITHDIFVVR........
M3ZTD8_XIPMA/1509-1549                 ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVYDLFVLR........
H2PCR6_PONAB/1503-1543                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
L5K4U1_PTEAL/1583-1623                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A091GWG1_BUCRH/1490-1530             ..QIIGIPKIIHLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
HD_TAKRU/1508-1548                     ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
B7ZDE9_DANRE/1487-1527                 ..QIISIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A091U1H3_PHORB/1430-1470             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A091LPU0_CARIC/1506-1546             ..QIIGIPKIIQLCDGIMASERKAVTH.A.........IPAL.....QPIVHDLFVLR........
F7BQH8_HORSE/1432-1472                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
A0A091F031_CORBR/1435-1475             ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
G5BZF2_HETGA/1386-1426                 ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
I1GHU9_AMPQE/1141-1180                 .k-LITIPEVMQKCDSVMASGQNMISF.A.........IPAL.....QPLVLYLFV--r.......
#=GC seq_cons                          ..QIIGIPKIIQLCDGIMASGRKAVTH.A.........IPAL.....QPIVHDLFVLR........
//
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