GenomeNet

Database: Pfam
Entry: DUF3652
LinkDB: DUF3652
Original site: DUF3652 
#=GF ID   DUF3652
#=GF AC   PF12372.3
#=GF DE   Huntingtin protein region 
#=GF AU   Gavin OL
#=GF SE   Prosite
#=GF GA   20.90 20.90;
#=GF TC   21.10 21.30;
#=GF NC   19.90 20.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   7647777
#=GF RT   Cellular localization of the Huntington's disease protein and
#=GF RT   discrimination of the normal and mutated form.
#=GF RA   Trottier Y, Devys D, Imbert G, Saudou F, An I, Lutz Y, Weber C,
#=GF RA   Agid Y, Hirsch EC, Mandel JL;
#=GF RL   Nat Genet. 1995;10:104-110.
#=GF DR   INTERPRO; IPR024613;
#=GF CC   This domain family is found in eukaryotes, and is approximately
#=GF CC   40 amino acids in length. The family is found in association
#=GF CC   with Pfam:PF02985. This family is in the middle region of the
#=GF CC   Huntingtin protein associated with Huntington's disease. The
#=GF CC   protein is of unknown function, however it is known that a
#=GF CC   polyglutamine (CAG) repeat in the gene coding for it results in
#=GF CC   the development of Huntington's disease.
#=GF SQ   142
#=GS H2ZNB5_CIOSA/1426-1468  AC H2ZNB5.1
#=GS B0R1W9_STRPU/190-232    AC B0R1W9.1
#=GS A7RGU1_NEMVE/1539-1569  AC A7RGU1.1
#=GS A5A9V2_CIOIN/1321-1363  AC A5A9V2.1
#=GS E9QKY1_MOUSE/1696-1733  AC E9QKY1.1
#=GS G1M886_AILME/2202-2239  AC G1M886.1
#=GS HD_MOUSE/1491-1533      AC P42859.2
#=GS HD_HUMAN/1511-1553      AC P42858.2
#=GS H2SJ18_TAKRU/1516-1558  AC H2SJ18.1
#=GS G1NJV8_MELGA/1448-1490  AC G1NJV8.2
#=GS H0V9L0_CAVPO/2201-2238  AC H0V9L0.1
#=GS Q9U999_DROME/2462-2506  AC Q9U999.1
#=GS B5DYE6_DROPS/2806-2850  AC B5DYE6.1
#=GS H0ZJI1_TAEGU/931-973    AC H0ZJI1.1
#=GS F1S8N5_PIG/1517-1559    AC F1S8N5.1
#=GS Q9U999_DROME/2716-2760  AC Q9U999.1
#=GS B7XBM1_CALJA/2186-2223  AC B7XBM1.1
#=GS B0L1U1_BRAFL/1459-1501  AC B0L1U1.1
#=GS B4N8Q2_DROWI/2699-2742  AC B4N8Q2.1
#=GS F1P7Y7_CANFA/1507-1549  AC F1P7Y7.1
#=GS B3P5R0_DROER/2450-2494  AC B3P5R0.1
#=GS G3GWA8_CRIGR/1984-2021  AC G3GWA8.1
#=GS G1M886_AILME/1517-1559  AC G1M886.1
#=GS G3W1T8_SARHA/1430-1472  AC G3W1T8.1
#=GS H9KNL1_APIME/1285-1327  AC H9KNL1.1
#=GS Q9GM99_PIG/1512-1554    AC Q9GM99.1
#=GS F1LPV9_RAT/1485-1527    AC F1LPV9.1
#=GS G3GWA8_CRIGR/1298-1340  AC G3GWA8.1
#=GS B4M193_DROVI/2263-2301  AC B4M193.1
#=GS H3IDB5_STRPU/693-721    AC H3IDB5.1
#=GS H3D3C4_TETNG/1478-1520  AC H3D3C4.1
#=GS F6XPL5_CALJA/1501-1543  AC F6XPL5.1
#=GS H2ZNB8_CIOSA/1352-1394  AC H2ZNB8.1
#=GS G5BZF2_HETGA/2071-2108  AC G5BZF2.1
#=GS H0WWN4_OTOGA/1475-1517  AC H0WWN4.1
#=GS B4HZ09_DROSE/2707-2751  AC B4HZ09.1
#=GS B4PQQ6_DROYA/2481-2525  AC B4PQQ6.1
#=GS D3ZK38_RAT/1689-1726    AC D3ZK38.1
#=GS B4GP12_DROPE/2548-2592  AC B4GP12.1
#=GS E2AM71_CAMFO/1288-1330  AC E2AM71.1
#=GS Q4S7T9_TETNG/1399-1441  AC Q4S7T9.1
#=GS B4HZ09_DROSE/2452-2489  AC B4HZ09.1
#=GS HD_HUMAN/2196-2233      AC P42858.2
#=GS B0R1Y3_STRPU/1-27       AC B0R1Y3.1
#=GS B3LV94_DROAN/2692-2736  AC B3LV94.1
#=GS E1B8E7_BOVIN/2191-2228  AC E1B8E7.1
#=GS O42269_DANRE/1485-1527  AC O42269.3
#=GS H3AAE1_LATCH/1487-1529  AC H3AAE1.1
#=GS E1B8E7_BOVIN/1507-1549  AC E1B8E7.1
#=GS G3Q318_GASAC/1509-1551  AC G3Q318.1
#=GS B4M193_DROVI/2511-2555  AC B4M193.1
#=GS E9J746_SOLIN/1258-1300  AC E9J746.1
#=GS G3V9P7_RAT/2176-2213    AC G3V9P7.1
#=GS G1P179_MYOLU/1501-1543  AC G1P179.1
#=GS F6ZCK5_CALJA/1523-1565  AC F6ZCK5.1
#=GS H2QP49_PANTR/1483-1525  AC H2QP49.1
#=GS B5DYE6_DROPS/2550-2594  AC B5DYE6.1
#=GS E2C517_HARSA/1281-1323  AC E2C517.1
#=GS B4GP12_DROPE/2791-2835  AC B4GP12.1
#=GS HD_TAKRU/1506-1548      AC P51112.1
#=GS E1BZK0_CHICK/1494-1536  AC E1BZK0.1
#=GS H3C3K9_TETNG/914-956    AC H3C3K9.1
#=GS F7C6C4_MONDO/1439-1481  AC F7C6C4.1
#=GS F1P7Y7_CANFA/2192-2229  AC F1P7Y7.1
#=GS H0V9L0_CAVPO/1516-1558  AC H0V9L0.1
#=GS G1QHE5_NOMLE/2163-2200  AC G1QHE5.1
#=GS F6Z217_XENTR/1504-1546  AC F6Z217.1
#=GS E9QKY1_MOUSE/1492-1525  AC E9QKY1.1
#=GS D6X048_TRICA/1234-1276  AC D6X048.1
#=GS HD_MOUSE/2175-2212      AC P42859.2
#=GS Q9GM99_PIG/2196-2233    AC Q9GM99.1
#=GS H2MI92_ORYLA/1504-1546  AC H2MI92.1
#=GS G5BZF2_HETGA/1384-1426  AC G5BZF2.1
#=GS HD_RAT/2166-2203        AC P51111.1
#=GS Q9V3N4_DROME/2461-2505  AC Q9V3N4.1
#=GS G3TAJ5_LOXAF/2182-2219  AC G3TAJ5.1
#=GS G1KE86_ANOCA/1509-1551  AC G1KE86.1
#=GS G3UGQ6_LOXAF/2129-2166  AC G3UGQ6.1
#=GS Q59FF4_HUMAN/909-951    AC Q59FF4.1
#=GS B0R1X5_STRPU/1-27       AC B0R1X5.1
#=GS B7U9A4_SHEEP/2185-2221  AC B7U9A4.1
#=GS D2H4H2_AILME/2114-2151  AC D2H4H2.1
#=GS H2ZNB7_CIOSA/1431-1473  AC H2ZNB7.1
#=GS F6VQZ3_MACMU/2205-2242  AC F6VQZ3.1
#=GS G3V9P7_RAT/1492-1534    AC G3V9P7.1
#=GS F7C6D8_MONDO/1429-1471  AC F7C6D8.1
#=GS G3UGQ6_LOXAF/1444-1486  AC G3UGQ6.1
#=GS B4QYS8_DROSI/3351-3395  AC B4QYS8.1
#=GS F1LPV9_RAT/2169-2206    AC F1LPV9.1
#=GS G3X9H5_MOUSE/2176-2213  AC G3X9H5.1
#=GS G7NVR7_MACFA/1423-1465  AC G7NVR7.1
#=GS E1C543_CHICK/1519-1561  AC E1C543.1
#=GS G3RMC4_GORGO/1429-1471  AC G3RMC4.1
#=GS F7BQH8_HORSE/2115-2152  AC F7BQH8.1
#=GS B4JXS7_DROGR/2433-2476  AC B4JXS7.1
#=GS B0R1X3_STRPU/190-232    AC B0R1X3.1
#=GS C3ZGJ9_BRAFL/1376-1418  AC C3ZGJ9.1
#=GS B4QYS8_DROSI/3097-3141  AC B4QYS8.1
#=GS G3X9H5_MOUSE/1492-1534  AC G3X9H5.1
#=GS E9GU71_DAPPU/1091-1133  AC E9GU71.1
#=GS F6VQZ3_MACMU/1518-1560  AC F6VQZ3.1
#=GS A0PD97_CIOIN/1320-1362  AC A0PD97.1
#=GS B7U9A4_SHEEP/1500-1542  AC B7U9A4.1
#=GS B4PQQ6_DROYA/2738-2782  AC B4PQQ6.1
#=GS B4N8Q2_DROWI/2201-2246  AC B4N8Q2.1
#=GS F4W9A2_ACREC/1284-1326  AC F4W9A2.1
#=GS G3RJY1_GORGO/2034-2071  AC G3RJY1.1
#=GS D3DVR8_HUMAN/966-1008   AC D3DVR8.1
#=GS G3Q320_GASAC/1503-1545  AC G3Q320.1
#=GS B3P5R0_DROER/2704-2748  AC B3P5R0.1
#=GS B7XBM1_CALJA/1501-1543  AC B7XBM1.1
#=GS H2QP49_PANTR/2168-2205  AC H2QP49.1
#=GS H9HB29_ATTCE/1282-1324  AC H9HB29.1
#=GS B3LV94_DROAN/2440-2484  AC B3LV94.1
#=GS D2H4H2_AILME/1429-1471  AC D2H4H2.1
#=GS G1SY00_RABIT/1472-1514  AC G1SY00.1
#=GS HD_RAT/1482-1524        AC P51111.1
#=GS A4VAL4_BRAFL/1432-1474  AC A4VAL4.1
#=GS H2PCR6_PONAB/1501-1543  AC H2PCR6.1
#=GS D3ZK38_RAT/1485-1517    AC D3ZK38.1
#=GS G1QHE5_NOMLE/1480-1521  AC G1QHE5.1
#=GS H2PCR6_PONAB/2186-2223  AC H2PCR6.1
#=GS B3S350_TRIAD/961-1003   AC B3S350.1
#=GS G3RMC4_GORGO/2114-2151  AC G3RMC4.1
#=GS B0R1X1_STRPU/190-232    AC B0R1X1.1
#=GS G3TAJ5_LOXAF/1497-1539  AC G3TAJ5.1
#=GS G7MFT1_MACMU/1423-1465  AC G7MFT1.1
#=GS G3RJY1_GORGO/1349-1391  AC G3RJY1.1
#=GS H9F754_MACMU/1436-1478  AC H9F754.1
#=GS F1S8N5_PIG/2201-2238    AC F1S8N5.1
#=GS G9K505_MUSPF/36-78      AC G9K505.1
#=GS F7BQH8_HORSE/1430-1472  AC F7BQH8.1
#=GS H9F754_MACMU/2121-2158  AC H9F754.1
#=GS B4K7Q9_DROMO/2527-2571  AC B4K7Q9.1
#=GS A4VAL3_STRPU/1514-1547  AC A4VAL3.1
#=GS Q9V3N4_DROME/2715-2759  AC Q9V3N4.1
#=GS B7ZDE9_DANRE/1485-1527  AC B7ZDE9.1
#=GS B0R1X9_STRPU/1-27       AC B0R1X9.1
#=GS G7NVR7_MACFA/2108-2145  AC G7NVR7.1
#=GS H2SJ19_TAKRU/914-956    AC H2SJ19.1
#=GS D3DVR8_HUMAN/1651-1688  AC D3DVR8.1
#=GS G7MFT1_MACMU/2108-2145  AC G7MFT1.1
H2ZNB5_CIOSA/1426-1468             .sk--SVITMSK.....II.QLCDGLMASEQGSASHVI..PAMQPITHDIFVVR....
B0R1W9_STRPU/190-232               ..s-KPVIAMPK.....II.QLCDGIMASGQQASTHIV..PALKPLVHDLFILR....
A7RGU1_NEMVE/1539-1569             ..a-KAIVGMAK.....VI.QLCDGIMASGQSAKTHG-..--------------rdm.
A5A9V2_CIOIN/1321-1363             ...TKAVITMPK.....II.QLCDGLMASGQGSASHVI..PAMQPIIHDIYVVR....
E9QKY1_MOUSE/1696-1733             ...IEPTAYWNK.....L-.NDLLGDTTSYQSLTILA-..---RALAQYLVVLS....
G1M886_AILME/2202-2239             ...VEPTAYWSK.....L-.NDLFGDAVLYRSLTTLA-..---RALAQYLLV--fs..
HD_MOUSE/1491-1533                 ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
HD_HUMAN/1511-1553                 ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
H2SJ18_TAKRU/1516-1558             ..s-KQIISIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
G1NJV8_MELGA/1448-1490             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
H0V9L0_CAVPO/2201-2238             ...TKLTAYWSK.....L-.NDLFGDATLYQSLTTLA-..---RALAQYLVVV-s...
Q9U999_DROME/2462-2506             ...RRLSAQSGQparnvIYeRLVEGDLAGGEDQDALR-..---TLLLKDLECRQ....
B5DYE6_DROPS/2806-2850             ...MDALLQQPR.....VW.RDLNASTDAALRCELLEVlcHSARCMLQETIFYQ....
H0ZJI1_TAEGU/931-973               ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
F1S8N5_PIG/1517-1559               ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
Q9U999_DROME/2716-2760             vnt---LLQQPR.....VW.RELNASSDPSLRCELLDLldSVARCILQDTIFYR....
B7XBM1_CALJA/2186-2223             ..a-EPAAYWSK.....L-.NDLFGDAALYQSLTTLA-..---RALAQYLVVV-s...
B0L1U1_BRAFL/1459-1501             ..s-KSIIVMPR.....II.QLCDGVMASGQKATNHAI..PALQPIVHDLFVLR....
B4N8Q2_DROWI/2699-2742             ...IDALLQHPR.....IW.REVNAST-TGVRSELLEVltMTGRCLLQDTIFYQ....
F1P7Y7_CANFA/1507-1549             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
B3P5R0_DROER/2450-2494             ...RRLSAQSGQparnvIYeRLVEGDLAGGEDQDALR-..---TLLLKDLECRQ....
G3GWA8_CRIGR/1984-2021             ...TEPTAYWSK.....L-.NDLLGDATSYQSLTTLA-..---RALAQYLVVV-s...
G1M886_AILME/1517-1559             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
G3W1T8_SARHA/1430-1472             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
H9KNL1_APIME/1285-1327             ..s-KAIIGIPK.....II.QLCDGLMASGQPALTYCI..PALAPVVEDVF---lir.
Q9GM99_PIG/1512-1554               ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
F1LPV9_RAT/1485-1527               ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
G3GWA8_CRIGR/1298-1340             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
B4M193_DROVI/2263-2301             ...ISEINYFAK.....VLsEKLLGCLDALL-ALGSG-..---STLAGHAYCQL....
H3IDB5_STRPU/693-721               ..s-KPVIAMPK.....II.QLCDGIMASGQQASTHS-..--------------k...
H3D3C4_TETNG/1478-1520             ..s-KQIISIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
F6XPL5_CALJA/1501-1543             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
H2ZNB8_CIOSA/1352-1394             .sk--SVITMSK.....II.QLCDGLMASEQGSASHVI..PAMQPITHDIFVVR....
G5BZF2_HETGA/2071-2108             ..t-QPTAYWSK.....L-.NGLFGDATLYQSLTTLA-..---RALAQYLVVV-s...
H0WWN4_OTOGA/1475-1517             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
B4HZ09_DROSE/2707-2751             .vn--ALLQQPR.....VW.RELNASLDHSLRCELLDLldSVARCILQDTIFYR....
B4PQQ6_DROYA/2481-2525             ...RRLSAQSGQaarnvIYeRLVEGDLAGGEDQDALR-..---TLLLKDLECRQ....
D3ZK38_RAT/1689-1726               ...TEPTAYWSK.....L-.NDLFGDTTSYQSLTTLA-..---RALAQYLVVLS....
B4GP12_DROPE/2548-2592             ...RRLTAQSGPaaraiIYeRLLDGDLAGGEDQDAMR-..---TLLLKDLECQQ....
E2AM71_CAMFO/1288-1330             ..s-KAIIGIPK.....II.QLCDGLMASGQPAITHCI..PALAPVIEDIF---lir.
Q4S7T9_TETNG/1399-1441             ..s-KQIISIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
B4HZ09_DROSE/2452-2489             ...RRLSAQSGQparnvIYeRLVEGDLAGGEDQDALR-..---TLL--------t...
HD_HUMAN/2196-2233                 ..a-EPAAYWSK.....L-.NDLFGDAALYQSLPTLA-..---RALAQYLVVV-s...
B0R1Y3_STRPU/1-27                  ...---------.....--.-----IMASGQQASTHIV..PALKPLVHDLFILR....
B3LV94_DROAN/2692-2736             ...VDALLLQPR.....VW.RDLNARLDPGPRCDLLELldRVSGCILQDTIFYQ....
E1B8E7_BOVIN/2191-2228             ..t-QPSAYWSK.....L-.DDLFGDAALYRTLTTLA-..---QALAQYLLV--fs..
O42269_DANRE/1485-1527             ..s-KQIISIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
H3AAE1_LATCH/1487-1529             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
E1B8E7_BOVIN/1507-1549             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
G3Q318_GASAC/1509-1551             ..s-KQIISIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
B4M193_DROVI/2511-2555             ...RRLAAQSSPatrssIYeRLLQGELAGDEDQDELR-..---TMLLKDLEYPQ....
E9J746_SOLIN/1258-1300             .sk--VIIGIPK.....II.QLCDGLMASGQPAISHCI..PALAPVIEDIF---lir.
G3V9P7_RAT/2176-2213               ...TEPTAYWSK.....L-.NDLFGDTTSYQSLTTLA-..---RALAQYLVVLS....
G1P179_MYOLU/1501-1543             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
F6ZCK5_CALJA/1523-1565             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
H2QP49_PANTR/1483-1525             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
B5DYE6_DROPS/2550-2594             ...RRLTAQSGPaaraiIYeRLLDGDLAGGEDQDAMR-..---TLLLKDLECQQ....
E2C517_HARSA/1281-1323             ..s-KAIIGIPK.....II.QLCDGLMASGQPAISHCI..PALAPVIEDIF---lir.
B4GP12_DROPE/2791-2835             ...MDALLQQPR.....VW.RDLNASTDAALRCELLEVlcHSARCMLQETIFYQ....
HD_TAKRU/1506-1548                 ..s-KQIISIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
E1BZK0_CHICK/1494-1536             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
H3C3K9_TETNG/914-956               ..s-KQIISIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
F7C6C4_MONDO/1439-1481             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
F1P7Y7_CANFA/2192-2229             ...MEPTAYWSK.....L-.NDLFGDAVLYRSLTTLA-..---RALAQYLLV--fs..
H0V9L0_CAVPO/1516-1558             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
G1QHE5_NOMLE/2163-2200             ..a-EPAAYWSK.....L-.NDLFGDAALYQSLPTLA-..---RALAQYLVVV-s...
F6Z217_XENTR/1504-1546             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
E9QKY1_MOUSE/1492-1525             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHGI..SA------------nlq.
D6X048_TRICA/1234-1276             ..s-KSIITVPK.....II.HLCDGLMASEQSPLTHCI..PALEPIVENIF---ltr.
HD_MOUSE/2175-2212                 ...IEPTAYWNK.....L-.NDLLGDTTSYQSLTILA-..---RALAQYLVVLS....
Q9GM99_PIG/2196-2233               ...TEPAAYWSK.....L-.DDLFGDAVLYRSLTTLA-..---RALAQYLLVLS....
H2MI92_ORYLA/1504-1546             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFILR....
G5BZF2_HETGA/1384-1426             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
HD_RAT/2166-2203                   ...TEPTAYWSK.....L-.NDLFGDTTSYQSLTTLA-..---RALAQYLVVLS....
Q9V3N4_DROME/2461-2505             ...RRLSAQSGQparnvIYeRLVEGDLAGGEDQDALR-..---TLLLKDLECRQ....
G3TAJ5_LOXAF/2182-2219             ..a-EASAYWSK.....L-.NDLFGDTTLYQAMTTLA-..---RALAQYLMVL-s...
G1KE86_ANOCA/1509-1551             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFILR....
G3UGQ6_LOXAF/2129-2166             ..a-EASAYWSK.....L-.NDLFGDTTLYQAMTTLA-..---RALAQYLMVL-s...
Q59FF4_HUMAN/909-951               ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
B0R1X5_STRPU/1-27                  ...---------.....--.-----IMASGQQASTHIV..PALKPLVHDLFILR....
B7U9A4_SHEEP/2185-2221             ..q--PATYWSK.....L-.DDLFGDAALYRTLTTLA-..---RALAQYLLV--fs..
D2H4H2_AILME/2114-2151             ...VEPTAYWSK.....L-.NDLFGDAVLYRSLTTLA-..---RALAQYLLV--fs..
H2ZNB7_CIOSA/1431-1473             .sk--SVITMSK.....II.QLCDGLMASEQGSASHVI..PAMQPITHDIFVVR....
F6VQZ3_MACMU/2205-2242             ..a-EPAAYWSK.....L-.NDLFGDAALYQSLTTLA-..---RALAQYLV---avs.
G3V9P7_RAT/1492-1534               ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
F7C6D8_MONDO/1429-1471             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
G3UGQ6_LOXAF/1444-1486             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
B4QYS8_DROSI/3351-3395             .vn--ALLQQPR.....VW.RELNASLNPSLRCELLDLldSVARCILQDTIFYR....
F1LPV9_RAT/2169-2206               ...TEPTAYWSK.....L-.NDLFGDTTSYQSLTTLA-..---RALAQYLVVLS....
G3X9H5_MOUSE/2176-2213             ...IEPTAYWNK.....L-.NDLLGDTTSYQSLTILA-..---RALAQYLVVLS....
G7NVR7_MACFA/1423-1465             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
E1C543_CHICK/1519-1561             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
G3RMC4_GORGO/1429-1471             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
F7BQH8_HORSE/2115-2152             ..v-EPSTYWGK.....V-.NDLFGDAVLYRSLTTLA-..---RALAQYLLV--fs..
B4JXS7_DROGR/2433-2476             ...RRLFAQSTPttrsdIYdRLMHGELAGDEDQDELR-..---TMLLKDLE---wp..
B0R1X3_STRPU/190-232               ..s-KPVIAMPK.....II.QLCDGIMASGQQASTHIV..PALKPLVHDLFILR....
C3ZGJ9_BRAFL/1376-1418             ..s-KSIIVMPR.....II.QLCDGVMASGQKATNHAI..PALQPIVHDLFVLR....
B4QYS8_DROSI/3097-3141             ...RRLSAQSGQparnvIYeRLVEGDLAGGEDQDALR-..---TLLLKDLECRQ....
G3X9H5_MOUSE/1492-1534             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
E9GU71_DAPPU/1091-1133             .sk--TIISVPR.....IM.QLAGGLMATGKDAELHVL..PTLQPMVEDLF---lsr.
F6VQZ3_MACMU/1518-1560             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
A0PD97_CIOIN/1320-1362             ...TKAVITMPK.....II.QLCDGLMASGQGSASHVI..PAMQPIIHDIYVVR....
B7U9A4_SHEEP/1500-1542             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
B4PQQ6_DROYA/2738-2782             ...MDALLQEPR.....VW.RELNASLDPLLRCELLELldSVARCILQDTIFYR....
B4N8Q2_DROWI/2201-2246             ...ISEINYFAK.....VLsEKLLGCLDALLHGLDPHSypDAEPCLVGNAYCHL....
F4W9A2_ACREC/1284-1326             ..s-KAIIGIPK.....II.QLCDGLMASGQPAISHCI..PALAPVIEDIF---lir.
G3RJY1_GORGO/2034-2071             ..a-EPAAYLSK.....L-.NDLFGDAALYQSLPTLA-..---RALAQYLVVV-s...
D3DVR8_HUMAN/966-1008              ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
G3Q320_GASAC/1503-1545             ..s-KQIISIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
B3P5R0_DROER/2704-2748             ...VDALLQQPR.....VW.RELNASLDPSLRCELLDLldSVARCILLDTIFYR....
B7XBM1_CALJA/1501-1543             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
H2QP49_PANTR/2168-2205             ..a-EPAAYWSK.....L-.NDLFGDAALYQSLPTLA-..---RALAQYLVVV-s...
H9HB29_ATTCE/1282-1324             ..s-KAIIGIPK.....II.QLCDGLMASGQPAISHCI..PALAPVIEDIF---lir.
B3LV94_DROAN/2440-2484             ...RRLTAQSGNgirnvIYeQLIEGELAGGDDQDALR-..---TLLLKDLECRQ....
D2H4H2_AILME/1429-1471             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
G1SY00_RABIT/1472-1514             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
HD_RAT/1482-1524                   ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
A4VAL4_BRAFL/1432-1474             ..s-KSIIVMPR.....II.QLCDGVMASGQKATNHAI..PALQPIVHDLFVLR....
H2PCR6_PONAB/1501-1543             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
D3ZK38_RAT/1485-1517               ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHDL..PAS-----------l...
G1QHE5_NOMLE/1480-1521             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHVC..PSLRAWWHD-----lgsl
H2PCR6_PONAB/2186-2223             ..a-EPAAYWSK.....L-.NDLFGDAALYQSLPTLA-..---RALAQYLVVV-s...
B3S350_TRIAD/961-1003              ..l-EPIVGIPR.....IL.QLSDGIMASGQLAPAHVI..PAFRPVVFDLFNVR....
G3RMC4_GORGO/2114-2151             ..a-EPAAYLSK.....L-.NDLFGDAALYQSLPTLA-..---RALAQYLVVV-s...
B0R1X1_STRPU/190-232               ..s-KPVIAMPK.....II.QLCDGIMASGQQASTHIV..PALKPLVHDLFILR....
G3TAJ5_LOXAF/1497-1539             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
G7MFT1_MACMU/1423-1465             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
G3RJY1_GORGO/1349-1391             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
H9F754_MACMU/1436-1478             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
F1S8N5_PIG/2201-2238               ...TEPAAYWSK.....L-.DDLFGDTVLYRSLTTLA-..---RALAQYLLVLS....
G9K505_MUSPF/36-78                 ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
F7BQH8_HORSE/1430-1472             ..s-KQIIGIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
H9F754_MACMU/2121-2158             ..a-EPAAYWSK.....L-.NDLFGDAALYQSLTTLA-..---RALAQYLV---avs.
B4K7Q9_DROMO/2527-2571             ...RRLTAQSSPairnsIYeQLVQGELAGGDDQDELR-..---TMLLKDLECPQ....
A4VAL3_STRPU/1514-1547             ..s-KPVIAMPK.....II.QLCDGIMASGQ-QLEMF-..---TAVL-------qqa.
Q9V3N4_DROME/2715-2759             vnt---LLQQPR.....VW.RELNASSDPSLRCELLDLldSVARCILQDTIFYR....
B7ZDE9_DANRE/1485-1527             ..s-KQIISIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
B0R1X9_STRPU/1-27                  ...---------.....--.-----IMASGQQASTHIV..PALKPLVHDLFILR....
G7NVR7_MACFA/2108-2145             ..a-EPAAYWSK.....L-.NDLFGDAALYQSLTTLA-..---RALAQYLV---avs.
H2SJ19_TAKRU/914-956               ..s-KQIISIPK.....II.QLCDGIMASGRKAVTHAI..PALQPIVHDLFVLR....
D3DVR8_HUMAN/1651-1688             ..a-EPAAYWSK.....L-.NDLFGDAALYQSLPTLA-..---RALAQYLVVV-s...
G7MFT1_MACMU/2108-2145             ..a-EPAAYWSK.....L-.NDLFGDAALYQSLTTLA-..---RALAQYLV---avs.
#=GC seq_cons                      ..u.+tllthPK.....Ih.pLs-GlMASGpcusThAl..sshpsllcDLhVlp....
//
DBGET integrated database retrieval system