GenomeNet

Database: Pfam
Entry: DUF3785
LinkDB: DUF3785
Original site: DUF3785 
#=GF ID   DUF3785
#=GF AC   PF12653.6
#=GF DE   Protein of unknown function (DUF3785)
#=GF AU   Bateman A
#=GF SE   Jackhmmer:Q181X2
#=GF GA   27.00 27.00;
#=GF TC   53.90 53.80;
#=GF NC   25.80 21.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR024210;
#=GF CC   This family of proteins is functionally uncharacterised.This
#=GF CC   family of proteins is found in bacteria. Proteins in this family
#=GF CC   are approximately 140 amino acids in length. These proteins
#=GF CC   share two CXXC motifs suggesting these are zinc binding
#=GF CC   proteins. This protein is found in clostridia in an operon with
#=GF CC   three signalling proteins, suggesting this protein may be a
#=GF CC   DNA-binding transcription regulator downstream of an as yet
#=GF CC   unknown signalling pathway (Bateman A pers obs).
#=GF SQ   25
#=GS Q8XK35_CLOPE/2-134      AC Q8XK35.1
#=GS Q181X2_PEPD6/4-139      AC Q181X2.1
#=GS A0A084J947_9CLOT/4-137  AC A0A084J947.1
#=GS R5XF76_9CLOT/2-137      AC R5XF76.1
#=GS T0PAC7_9CLOT/4-136      AC T0PAC7.1
#=GS N9WHK4_9CLOT/3-137      AC N9WHK4.1
#=GS B6FWA5_9FIRM/3-138      AC B6FWA5.1
#=GS M1MN48_9CLOT/3-136      AC M1MN48.1
#=GS A0A0B3VX37_9FIRM/2-138  AC A0A0B3VX37.1
#=GS B2TR01_CLOBB/3-139      AC B2TR01.1
#=GS G7MAR6_9CLOT/3-136      AC G7MAR6.1
#=GS V9HFA0_9CLOT/3-138      AC V9HFA0.1
#=GS K6TT62_9CLOT/3-136      AC K6TT62.1
#=GS U5MXI4_CLOSA/3-136      AC U5MXI4.1
#=GS A0A101WLL0_9FIRM/4-139  AC A0A101WLL0.1
#=GS S6EIT2_9CLOT/3-138      AC S6EIT2.1
#=GS A0A0C1RB24_9CLOT/3-135  AC A0A0C1RB24.1
#=GS R6FZ21_9CLOT/3-138      AC R6FZ21.1
#=GS A0A0A1S3S7_CLOSO/4-139  AC A0A0A1S3S7.1
#=GS A0A0A7FUK8_9CLOT/3-138  AC A0A0A7FUK8.1
#=GS T0CMU0_CLOSO/1-38       AC T0CMU0.1
#=GS C4ICU6_CLOBU/3-136      AC C4ICU6.1
#=GS L1Q454_9CLOT/7-142      AC L1Q454.1
#=GS A6M318_CLOB8/3-136      AC A6M318.1
#=GS U2Q069_9CLOT/2-137      AC U2Q069.1
Q8XK35_CLOPE/2-134                 .FSFTFDEKEYTLSEDKLLYFFNED--...-VEGFDIDKLFEILNSS.EGVSFGKAYYDGPCEECKFGLEEKKKSFPFLEFNMFIYAKNGKFVISNIEKAYEGLTYNKLLRDKKVDKSYLVNINVCKNCGNFAVEVEELEV.
Q181X2_PEPD6/4-139                 .YKFIYDDKEYLLKEENCSALINDEEN...PVQGVSISKIIDILNEA.EEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGLSFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV.
A0A084J947_9CLOT/4-137             .FKFKHKDEEFILSEDNLSYIEAEE--...-VQDFTIGKVLEILEEGkEKVEFDYEYYADNCEACGNSEAIDKKHYRYLEYHFYIFTKEGKYIISNISNEFETTTYSQLERMKKIDESYIVSIIICESCKNFAIEVEQCD-m
R5XF76_9CLOT/2-137                 l-KFVYDEKEYVLEKDKNVCFLNDEEK...PVEGISLDDILNMIDNL.EEIDFDTQYYKEACVECLDGVKEKQKFFAFLEYHFYIYTKDQKFIISDIQKEYEGQSFNKLLRANKVDDSYIVSLIICKNCGDTLIQIENCVV.
T0PAC7_9CLOT/4-136                 .YKFQYEDKEFELKEDNCDYINNEE--...-VENFNISTVLDLLNKG.EEVGFTVEYYDSCCEECKFNRKDDTKFFEFLEYHFYIFTKENNYVLSTISPEYQEVTLTSLVRDKKIDNSHIVSILVCKNCGTWAIEVEQCD-m
N9WHK4_9CLOT/3-137                 .YKFNFEKKEYILNEESLLELINDEES...PVEGFDLNEVLRLLNEG.N-LEFDKAYYSSSCDSCDSNFKEKRNVSEYVEGFFYIYTKNKKYVIANIDKDYEGKTYHKLELLGEVDDSYIVSIIICKNCGKFIIQIEELVV.
B6FWA5_9FIRM/3-138                 .YKFNCDGREYVLDSEKCSEFFNDEEK...EVSGFSVEEAMRLVSEA.EDVEFAKEYYQEACPDCMAGVKEKQKFFAFYEYHFYIFTKDGKYVISDIDKEYKGNSFNKLSRAGEVDDSYIVSIIVCAECGEYIVQVENCEV.
M1MN48_9CLOT/3-136                 .YKFAYDNKDYLLTNENCEGLFFEDDN...EIVGLSLDLILNALNEG.EDVAFSNEYYSGKC-SC-NTQDEVNKSYRYLEYHFYIYTKNKEYVINTIENEYKATSFNKLFNAGKIDDSYIVIVTACPNCGVYSISVEQCTV.
A0A0B3VX37_9FIRM/2-138             .FKFTFDEKEYILNDENFDELINDDEK...PVKNIDRDMIIELLNNSpEEIIFDEEFYIEACPKCLKGIKEKEKFFPFLEYHFYIYTKDGKYVISTIDKDYKGKSFNKLSRANLVDDSYIVSTIICKHCNDYIIQIENCEV.
B2TR01_CLOBB/3-139                 .YKFVYDDKEYLLSKENCDGIFLDSDNeseEIEGLSLDIVLNALSEG.EVINFSKEFYGDKC-YC-DSQEKINKSYAYLEYHFYIYTKENKYVINTLCKEYENTSYNKLARAGKIDNSYIVSVVVCPCCGNYTIEIEQCTV.
G7MAR6_9CLOT/3-136                 .YKFSHNGKEYVLTKENCDGIFFDDEA...TVSGLSMDIILDALNEG.EEVNFSNEYYMGKC-SC-NSQEEVNKSYRYLEYHFFIYTKNNQYVINTIGNEYKHTSFNQLFGFGKVDDSYIVSVTVCPNCGEYSISVEQCTV.
V9HFA0_9CLOT/3-138                 .YKFKFDEKEYILGEDNLEYFANDENE...ELEGIDGEKILELLSNS.DEVEFQNAYYESCCSNCKAGKEEKKKVFDFLEFYFYAYGKNNKFITSSIDNEYDKKSFTRLNRERIVDKSYLVTVIVCKNCGTYSIEIEEFE-l
K6TT62_9CLOT/3-136                 .YKFTHDNKEYILTKENCDGIFFEDEN...EVTGLSIDMILDALNEG.DEVSFSNEYYADKC-SC-NTQEQINKSYRYFEYHFYSYTKNNEYIINTISNEYKNTSFNKLFGLGKIDDSYIVSVTVCPNCGIYSVYVDQCTV.
U5MXI4_CLOSA/3-136                 .YTFIHENKEYVLSNDNCEGLFFEDEN...EITGLSFDIILEALNNS.NDVNFSNEYYVGKC-QC-GEQEKINKSYRYLEYHFYIYTKNNTYVINTISKEYENTSFNKLFNLGKVDDSYIINVTVCPICGLYAIEVSQCTV.
A0A101WLL0_9FIRM/4-139             .YSFVYNNKEYELGEDNCSYVINDEEH...PVAGIEGPDIIELLCGQ.ETVDFGIEYYDTPCQNCLAGKKEKSKYFKFLEYHFFIFTKEGRYVISNISKEYEDTSFNRLVKKGIVDNSYVASVAVCVECGDYSIEIEQCDV.
S6EIT2_9CLOT/3-138                 .YKFNFDGKEYELKEDNLDYFINDEEF...ELEGIDANKVLELLSNS.KEVEFERAYYETCCEECRAGKAEKKKVFDFLEFFFYAYAKDGKFITSSIDDDYEGKSFTKLYREGKVDCNYIVTVIVCKNCGTYSIEIEEFE-l
A0A0C1RB24_9CLOT/3-135             .YKFNFENREYELKEDNLEYIYDEN--...-IEGFEYETLIELLNNS.DKVSFDLEYFDGRCDVCEAGKGEGRKHYDFLEYHFFVFTKNNKYIISTISKDYEEGIYTDLYKRKVIDNDFIVSIIVCKECGAWMVEIEQCD-m
R6FZ21_9CLOT/3-138                 .YKFTFEGREYKLNEENLDYFVNDEEN...PIKNINLDKVLEIMANS.DEVDFAKEYFDMPCGECKEGVSEKKKFFAFLGYNFYIYTKNGEFVISSIDKEYEGLSFNRLQKAGKVDNSYIVLVNVCKHCGSYSVEIEEFE-i
A0A0A1S3S7_CLOSO/4-139             .YKFKFKDKEYELNKSNCSGVINDEDK...PVTNIDLDEVLRLLNET.QDVDFDLEYYQEACPECLSGVKEKQKFFGFLEYHFYLFTKNGEYVISDISKDYEGLSFNKLSRAGKVDDSYIVSIIMCESCSDYIVQIENCIV.
A0A0A7FUK8_9CLOT/3-138             .YIFKYEDKEIKLSKDNLIEVINDEEM...PIEDINIETIIKLLNEG.EDVKFEKAYYSTPCEKCDSNFKEKRNISEYLEYYFYVYTKDNKFVISDISKEYENLTYNRLELEGKVDNSYIVTVIVCANCNEYLVQIEEIEV.
T0CMU0_CLOSO/1-38                  .--------------------------...-----------------.-------------------------------------------------------MSFNKLSRAGKVDDSYIVSIIMCESCSDYIVQIENCIV.
C4ICU6_CLOBU/3-136                 .YKFTYNSKEYTLSSKNCEGIFFENYE...EIKGLSLETILEALNSN.EEVSFSKEYYAGKC-TC-DLQEKIEKYYCYLEYHFYIYTKEQEYVINTICKEYEDTSFNKLFRAGKIDKSHIVNITVCPECGTYSIEIEDCEV.
L1Q454_9CLOT/7-142                 n-KFSFDGKEYCLNEEKLDYFVNDEIN...PIEDIDEKKVIEILNNS.DNVEFTKAFFDLPCDVCKEGVSEKKKFFDFLGFNFYIYTKNNQYVVSTLDKEYEGMSYNRLQRSGKINGSYIVLINVCRNCGSYSIEIEEFEV.
A6M318_CLOB8/3-136                 .YKFVYENKEYVLTENNCDGIFFEGEN...EITGLSLDIILNALNEG.EEISFSTEYYGDKC-TC-NTQEQINKSYRYLEYHFYIYTKDNEYVINTICNEYKNTSFNKLFGLGKIDDSYIVSVTVCPNCGIYSIYIDQCTV.
U2Q069_9CLOT/2-137                 .YTLKFNEKTYELTENNCEDFIMDEEY...KIEGVSVKNILNLLNEA.ENISFDREYYSEYCSSCKEEDIVKSKFYEYLGYSFYIFTKDSKYVESNISESYKDSSFGRLFRSNVVDNSFIVNIIFCEKCNKYTIEIEQCD-m
#=GC seq_cons                      .YKFsa-sKEYhLsc-Nh-tlhsD--p....lpGlsl-plL-lLNpu.E-VsFspEYYsssC.pC.suhcEcpKhacaLEYHFYIYTKsscYVISsIscEY-spSFNKL.RtGKVDcSYIVSllVCcsCGsYsIpIEpCpV.
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