GenomeNet

Database: Pfam
Entry: DUF3830
LinkDB: DUF3830
Original site: DUF3830 
#=GF ID   DUF3830
#=GF AC   PF12903.4
#=GF DE   Protein of unknown function (DUF3830)
#=GF AU   Coggill P
#=GF SE   JCSG_target_392654_3kop
#=GF GA   21.30 21.30;
#=GF TC   21.90 21.40;
#=GF NC   20.80 20.10;
#=GF BM   hmmbuild --amino HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR024532;
#=GF CC   This is a family of bacterial and archaeal proteins, the
#=GF CC   structure for one of whose members has been characterised.
#=GF CC   PDB:3kop from Swiss:A0JVT3 probably adopts a new hexameric form
#=GF CC   compared to previous structures. The putative active is near the
#=GF CC   domain interface. 3kop is most closely related, structurally to
#=GF CC   PDB:1zx8, where the potential active site is located near
#=GF CC   residues E51 and Y53 (conserved in 1zx8). Beyond the two
#=GF CC   residues above, the other residues are not conserved. Also the
#=GF CC   shape of the active site differs from that of 1zx8. PDB:1zx8
#=GF CC   belongs to family DUF369. Pfam:PF04126, which is part of the
#=GF CC   cyclophilin-like clan.
#=GF SQ   87
#=GS A0A0A2I8F5_PENEN/6-139   AC A0A0A2I8F5.1
#=GS M1FG94_9ALTE/4-136       AC M1FG94.1
#=GS T0LCK9_COLGC/9-140       AC T0LCK9.1
#=GS B8LWZ3_TALSN/55-179      AC B8LWZ3.1
#=GS B5HNM0_9ACTN/8-163       AC B5HNM0.1
#=GS R4T372_AMYOR/7-164       AC R4T372.1
#=GS A0A0A8EQW5_9ACTN/8-165   AC A0A0A8EQW5.1
#=GS K4RAR3_9ACTN/8-163       AC K4RAR3.1
#=GS Q986W8_RHILO/8-161       AC Q986W8.1
#=GS Q13QC6_BURXL/4-140       AC Q13QC6.1
#=GS E6WBC5_PANSA/5-139       AC E6WBC5.1
#=GS B5HHY7_STRPR/8-165       AC B5HHY7.1
#=GS A0A0C4YE00_9BURK/4-136   AC A0A0C4YE00.1
#=GS D5WFL2_BURSC/4-140       AC D5WFL2.1
#=GS A0A0B5EVP8_9ACTN/1-100   AC A0A0B5EVP8.1
#=GS Q0JYD1_CUPNH/3-135       AC Q0JYD1.1
#=GS E4T2W2_PALPW/6-138       AC E4T2W2.1
#=GS B0UBT4_METS4/4-137       AC B0UBT4.1
#=GS A0A0B4Y2E7_9PROT/4-137   AC A0A0B4Y2E7.1
#=GS A0A0D5VPG1_9BURK/4-140   AC A0A0D5VPG1.1
#=GS N6YNL6_9RHOO/4-137       AC N6YNL6.1
#=GS A0A0D5LLA4_9RHIZ/3-136   AC A0A0D5LLA4.1
#=GS K0CIQ1_ALCDB/4-136       AC K0CIQ1.1
#=GS A0A059VWR7_STRA9/8-165   AC A0A059VWR7.1
#=GS D7BZP1_STRBB/1-151       AC D7BZP1.1
#=GS K7SNX7_PROA4/7-163       AC K7SNX7.1
#=GS D8JBC0_HALJB/4-139       AC D8JBC0.1
#=GS D3PZD9_STANL/7-164       AC D3PZD9.1
#=GS B1MJX9_MYCA9/7-163       AC B1MJX9.1
#=GS J9RRA8_9ACTN/19-175      AC J9RRA8.1
#=GS G0G6G1_AMYMS/7-164       AC G0G6G1.1
#=GS B9JL19_AGRRK/3-137       AC B9JL19.1
#=GS C7MX78_SACVD/7-164       AC C7MX78.1
#=GS A0A0C5L3Q3_9SPHN/7-159   AC A0A0C5L3Q3.1
#=GS A0JVT3_ARTS2/7-164       AC A0JVT3.1
#=GS A0JVT3_ARTS2/7-164       DR PDB; 3KOP B; 7-164;
#=GS A0JVT3_ARTS2/7-164       DR PDB; 3KOP F; 7-164;
#=GS A0JVT3_ARTS2/7-164       DR PDB; 3KOP D; 7-164;
#=GS A0JVT3_ARTS2/7-164       DR PDB; 3KOP A; 7-164;
#=GS A0JVT3_ARTS2/7-164       DR PDB; 3KOP E; 7-164;
#=GS A0JVT3_ARTS2/7-164       DR PDB; 3KOP C; 7-164;
#=GS Q1LM09_RALME/4-136       AC Q1LM09.1
#=GS G2IVD6_PSEUL/4-137       AC G2IVD6.1
#=GS M1XTJ2_NATM8/2-137       AC M1XTJ2.1
#=GS H6R413_NOCCG/7-163       AC H6R413.1
#=GS D1C922_SPHTD/4-138       AC D1C922.1
#=GS D0L4M4_GORB4/8-164       AC D0L4M4.1
#=GS C8X321_DESRD/38-170      AC C8X321.1
#=GS W5TLN4_9NOCA/7-163       AC W5TLN4.1
#=GS D3F583_CONWI/28-159      AC D3F583.1
#=GS Q13WR5_BURXL/7-139       AC Q13WR5.1
#=GS J7L2H7_NOCAA/7-161       AC J7L2H7.1
#=GS A0A089YV92_9PSED/4-141   AC A0A089YV92.1
#=GS K0F3E7_9NOCA/7-163       AC K0F3E7.1
#=GS D8MR05_ERWBE/5-99        AC D8MR05.1
#=GS B2JLB6_BURP8/4-138       AC B2JLB6.1
#=GS U7Q035_SPOS1/7-141       AC U7Q035.1
#=GS A0A023X2C9_9ACTN/4-137   AC A0A023X2C9.1
#=GS A0A0D4DT93_9ACTN/21-178  AC A0A0D4DT93.1
#=GS B6QPT5_PENMQ/8-140       AC B6QPT5.1
#=GS Q1AS70_RUBXD/4-137       AC Q1AS70.1
#=GS V6K3J1_STRNV/8-165       AC V6K3J1.1
#=GS A0A0D5LLI2_9RHIZ/8-156   AC A0A0D5LLI2.1
#=GS Q881W0_PSESM/4-141       AC Q881W0.1
#=GS B9LWF6_HALLT/2-137       AC B9LWF6.1
#=GS A0A0B4X1K7_9RHIZ/4-137   AC A0A0B4X1K7.1
#=GS Q82CV7_STRAW/8-161       AC Q82CV7.1
#=GS S5URS4_STRCU/8-163       AC S5URS4.1
#=GS Q93J70_STRCO/11-166      AC Q93J70.1
#=GS V4IVH7_9ACTN/8-166       AC V4IVH7.1
#=GS A0QV99_MYCS2/7-164       AC A0QV99.1
#=GS Q89H30_BRADU/4-137       AC Q89H30.1
#=GS Q24P94_DESHY/4-138       AC Q24P94.1
#=GS D7B049_NOCDD/3-157       AC D7B049.1
#=GS V9XKL5_9NOCA/7-163       AC V9XKL5.1
#=GS V6JZW3_STRRC/8-163       AC V6JZW3.1
#=GS L2FC62_COLGN/10-131      AC L2FC62.1
#=GS A4FG67_SACEN/7-161       AC A4FG67.1
#=GS W0AED6_9SPHN/6-159       AC W0AED6.1
#=GS F4CME6_PSEUX/22-178      AC F4CME6.1
#=GS L0K3G5_9EURY/4-138       AC L0K3G5.1
#=GS H5X7Z0_9PSEU/7-164       AC H5X7Z0.1
#=GS D4GPV2_HALVD/2-137       AC D4GPV2.1
#=GS F5YYE8_MYCSD/7-162       AC F5YYE8.1
#=GS C4ZM00_THASP/4-137       AC C4ZM00.1
#=GS I1D5M9_9PSEU/7-164       AC I1D5M9.1
#=GS Q0S805_RHOJR/7-163       AC Q0S805.1
#=GS E8TB59_MESCW/6-159       AC E8TB59.1
#=GS G2NX92_STRVO/11-168      AC G2NX92.1
#=GS A0A0A1DG62_NOCSI/12-160  AC A0A0A1DG62.1
#=GS W0I349_9ENTR/9-126       AC W0I349.1
#=GS A0A0A2L0B1_PENEN/4-137   AC A0A0A2L0B1.1
#=GS F2J3Z8_POLGS/8-157       AC F2J3Z8.1
A0A0A2I8F5_PENEN/6-139              .....ilitagp-------YQFLAKL-ESAAPKTVKLFRSLL...PYRQKLIHVRWSGEGMWIP.LGEAN......-FNLPFENHTAHPAPGQILLY-------..--PGGISE..............TEFLFCYGGVAFASKMGALAANHFLT.I.TEGSENLHALGKLTLWKGAQDVLFE---lad..................................................................
M1FG94_9ALTE/4-136                  ...........i-AITVGQFRFVAETHP-EAPETVAAFLKLL...PYRQKLIHVRWSGEACWIP.MGEFK......-LGIGFENHTCHPSVGDVLFY-------..--PGGFSE..............TEIIMAYGSCSFASKMGPLAGNHYLT.I.VEGKEHLRALGTKVLWEGAQDIVFE---ll...................................................................
T0LCK9_COLGC/9-140                  .itagpyqflaa--------------FESAAPKTVAVFRNLL...PYRQQLIHVRWSGEAVWVP.LGEED......-FGLGFENHTSHPGAGQILLY-------..--PGGYSE..............TELLFCYGGVSFASKMGSLSANHFLT.I.TEGAENLRALGELVLWKGAQDVLFE---lad..................................................................
B8LWZ3_TALSN/55-179                 .......flghf---------------ESKAPKTSALFRSLL...PYHQKLIHVRWSGEGLWIP.LGEIY......-FEVSYENHTSHPSAGQILLY-------..--PGKISE..............TEFLFCYGGVSFASKMGPLAANHFLT.V.KEGNENLRELGELVLWKGAQDVVFEV--ad...................................................................
B5HNM0_9ACTN/8-163                  ............VSLVKRGITATAKLLDDRAPITCAAVWDAL...PLAGDVYHAKYARNEIYAL.FPPFA......ETEPPLENPTVTPIPGDLCYFSFAGTEL..GTKSYGYDrevra...gttvvdLALFYERNNLLLNADVGWVPGIVWGQ.V.VEGLDALAEGCNDLWRSGALGESLRFSR.....................................................................
R4T372_AMYOR/7-164                  ............ITLDKRGVSCRARLLDAEAPRTCRAVWDAL...PQSGSAYHAKYARNEVYTL.VPPFA......EPKPGRENPTVTPIPGDVVYFGFEAWEI..GNPAYGYDegseah.sdqgatdLAIFYGRNNLLINGDAGWVPGNVFAT.I.EEGLAEMAEAAQDLWLRGVEGETLSFAR.....................................................................
A0A0A8EQW5_9ACTN/8-165              ............VSLDKRGVSCTAKLLDDRAPLTCAAIWDAL...PLGGDVYHAKYARNEIYAL.VPPFA......PEEPPLENPTVTPIPGDLCYFTFSDTQL..GTASYGYEsaakhr.gratvvdLALFYERNNLLINGDAGWVPGIVWGA.V.VEGLDRMADACQDLWRAGALGETLAFRR.....................................................................
K4RAR3_9ACTN/8-163                  ............ISLVKRDIHCTARLLADRAPLTCAAVWDAL...PLGGDVYHAKYARNEIYAL.FPPFA......DTEPPLENPTVTPIPGDLCYFAFAGAEL..GTRAYGYDrevrp...gttlvdLALFYERNNLLLNGDVGWVPGTVWGE.V.VEGLPRMAEACNDLWRTGAAGETLSFRR.....................................................................
Q986W8_RHILO/8-161                  ............ITEPSSKLSVTALLLPEKAPENVAFLLAYLt.aPRVVPGIHAMWTGPEISCP.VPSADldgqsyARPLPAENATLTPQPGDIVLSYVPPRMW.gGNPNAIFD..............IGLYYGQGARLL-FPIGWLAGSVVAQvL.PQEREQFAAACGVIRRNGACDITFSLV-e....................................................................
Q13QC6_BURXL/4-140                  ....lritscgh--------VFTAETHP-DAPHTVAAFLKLL...PYRQKIIHVRWSGEGCWVP.LGDFKle..ndGVAVGFENHTSHPSVGDILFY-------..--PGGYSE..............TEIILAYGSCCFASKLGQLAGNHFLT.I.VEGKEKLRELGTRVLWEGAQDVLF----eq...................................................................
E6WBC5_PANSA/5-139                  ......mhvadk-------KICVIEVWEDKVPNLAKVLREKL...PLKSVLQHGKLIGDMVFFT.LPIVA......----PWENKYLTQDVGK-----------..--------..............--------------------------.-.----------------------------lrreqygevtgavcyysprqqmcvvygddtadeplpisyigqviegklelrvtgletwfdqgrtvelsi
B5HHY7_STRPR/8-165                  ............VALSKRGVECTARLLFDKAPLTCAAVWEAL...PLAGDVYHAKYARNEIYAL.LPAFA......AQEPPLENPTVTPIPGDLCYFTFTDVQL..GTDSYGYEsgaahr.gratvvdLALFYERNNLLLNGDTGWVPGIVWGE.V.VEGLDVMAEACQDLWRTGAAGETLSFRR.....................................................................
A0A0C4YE00_9BURK/4-136              ...........i-RITAGGYQFVAETHPD-APLTVAAFTRLL...PYRQKLIHVRWSGEGCWIP.LGEFK......-LGVDFENHTSHPSVGDILFY-------..--PGGYSE..............TEIILAYGSCCFASKLGQLAGNHFLT.I.VQGKENLRALGTKVLWEGAQDVSFE---lm...................................................................
D5WFL2_BURSC/4-140                  ......lkmtac------GHTFIAETHP-DAPQTVAAFLKLL...PYRQKLIHVRWSGEGCWVP.LGEFKle..ndGVAVGFENHTSHPSVGDILFY-------..--PGGYSE..............TEIILAYGSCCFASKMGQLAGNHFLT.I.VEGKEKLRELGTKVLWEGAQEVVF----dr...................................................................
A0A0B5EVP8_9ACTN/1-100              ...........m------------------------------...-------------------.-----......------ENPTVTPIPGDLCYFSFNGTQL..GSQAYGYAsagaevkagatlvdLALFYERNNLLLNGDLGWIPGIVWGS.V.VEGLDRMADACQDLWRAGALGESLTFKR.....................................................................
Q0JYD1_CUPNH/3-135                  ...........i-EMKAGPYSFLARLEQDLSPAACDWLMERL...PAQWEFLQGRWSGHAVFAR.LGGTA......-KHIGNG-GISRPAVGQILLY---G---..GND--DVG..............GELLIPYGPTRFACPSGELSGHHVLT.V.TTGQERLADLGALIHERGGLSI------syrr.................................................................
E4T2W2_PALPW/6-138                  ........iite-----DKQEIRFNFYVDTAPTTSKAFIEIL...PFTRMFYHARVSGQEIWIDdVPPLD......---IIQENASVFTEPGEVVFGPMKPI--..-RSKTSNC..............FGIYYGNGKGLD-------ACNIFAKvF.DADKQKLIDLGNNIWKNGSQELTITF--ld...................................................................
B0UBT4_METS4/4-137                  .......lkika-----GPYDLVGRLELEKAPNTCAAFVKAL...PFVSEIVHVRWSGEGVWMP.LGDLD......-FGVGYENHTSYPAPGQMILY-------..--PGGISE..............TEILLAYGGVHFASKVGQLAGNHFLT.V.TTGLEHVYDLGRMTLYKGAQPIRF----dpa..................................................................
A0A0B4Y2E7_9PROT/4-137              .....ikitagp-------FTFDGGLEIDKAPQTCKAFMDRM...PFESKAVHVRWSGEGVWMP.LGDYQ......-FGVGYENHTSFPAPGQIILY-------..--PGGISE..............TEILLAYGGVHFASKVGQLAGNHFIT.V.ISNFEDLEKLGKMTLWEGAQPIRFE---iv...................................................................
A0A0D5VPG1_9BURK/4-140              ...lritacghv---------FTAETHP-DAPQTVAAFLKLL...PYRQKLIHVRWSGEGCWVP.LGDFKle..ndGAAVGFENHTSHPSVGDILFY-------..--PGGYSE..............TEIILAYGSCCFASKLGQLAGNHFLT.I.VEGKEKLRELGTKVLWEGAQDVLF----ek...................................................................
N6YNL6_9RHOO/4-137                  ...........l-AIDVGSFRFVARLEEAAAPKTCAAFLDLL...PFSNQVIHSRWSGEAVWVP.LGEFD......-TGLGFENHTSHPSRGDILLY-------..--PGGFSE..............TEILFAYGSSCFASKMGQLAGNHFLT.V.VEGMDQLYEMGRTVLWKGAQWIRFT---dl...................................................................
A0A0D5LLA4_9RHIZ/3-136              ....lkitagpf--------VFDAVLETESAPETCRSFAAHL...PFKSQVVHVRWSGEGVWIP.LGTKD......-FGVGYENHTSYPAPGQIVLY-------..--PGGISE..............TEILLAYGGVHFASKMGQLAGNHFIT.I.TSNLDKLAELGKMTLWEGAQDIVF----era..................................................................
K0CIQ1_ALCDB/4-136                  .........iri---TAGGFTFIAET-QADAPNTVAAFEALL...PYRQRLIHVRWSGEGCWIP.LGDWQ......-LGVAFENHTSHPSVGDILFY-------..--PGGYSE..............TEIIMAYGSCCFSSQMGQLAGNHFLS.I.VQGKENLRALGQKVLWEGAQDIVFE---ka...................................................................
A0A059VWR7_STRA9/8-165              ............VSLDKRGVSCTAKLLDDRAPLTCAAVWDAL...PLGGDVYHAKYARNEIYAL.VPPFA......PEEPPLENPTITPIPGDLCYFTFSDTQL..GTASYGYEsaakhr.gratvvdLALFYERNNLLINGDAGWVPGIVWGS.V.VDGLDRMADACQDLWRAGALGETLTFRR.....................................................................
D7BZP1_STRBB/1-151                  ...........m--------SCTAKLLDDRAPITCEAVWNAL...PLGGDVYHAKYARNEIYAL.LPPFA......PEEPPLENPTITPIPGDLCYFSFTDTQL..GTASYGYEqqakhq.gqqrvvdLALFYERNNLLINGDAGWVPGIVWGA.V.VDGLDRMADACQDLWRAGALGETLSFRR.....................................................................
K7SNX7_PROA4/7-163                  ............ITLEKRRVTAKALLLDDEAPRTCQAIWDSL...PIAGPAFHGKYARNEIYAF.VEPLV......-TEPGPENTTITPFTGDLCYFNFSNTAL..SNPGYGYEkesalp.gtgqvvdLALFYGRNNLLINGDQGWVPGNVYGR.I.VEGLDDVIAAGTDIWTNGFAGERFSYAR.....................................................................
D8JBC0_HALJB/4-139                  ...........l-EFEIEDRTFTAELHEDKAPESVAAMREFL...PLQSELMHVRWSGHATWIN.IDEIK......LPELPRENHTVYPSYGDILLY-------..--PGYRNE..............QEILVPCGSTCFKSPAGELAGNHVAT.L.DAPREELREMEQETLRTGMKDVTIRLT-e....................................................................
D3PZD9_STANL/7-164                  ............ISLDKRGVSCRAVLLDAEAPRTCKAVWNAL...PQSGSAYHAKYARNEVYTL.VPPFA......EPKPGRENPTVTPIPGDVCYFGFEAWEI..GNPAYGYDddseah.sdqgatdLAIFYGRNNLLINGDAGWVPGNVFAT.I.VEGLPEMAAAAQDLWLRGVEGETLSFSR.....................................................................
B1MJX9_MYCA9/7-163                  ............ITLTKRNVTCRARLLDAEAPRTCDTVWNSL...PVLGQAYHAKYARNEVYTL.LPPLL......-PAPGRENPTVTPIPGDVCFFGFEPWEI..GNPAYGYEpgseah.saqgatdLAIFYGRNNLLINGDAGWVPGNVFAT.I.EEGLSDIAAACQDLWLTGVQGEQLAFAR.....................................................................
J9RRA8_9ACTN/19-175                 ............VTLERRGVRAVARILDTEAPRTAAAVWDAL...PLGGQVFHGKFARNEIYTL.LPAFA......PAEPGMENTTITPIPGDLCYFTFDG-VL..ENPAYGYElgsapa.ehrllidLAVFYGRNNLLVNGDVGWVPGNVFAT.I.VEGLDEFAAACNDVWMGGARGETLTYAR.....................................................................
G0G6G1_AMYMS/7-164                  ............ITLDKRGVSCRARLLDDEAPRTCKAVWDAL...PQSGSAYHAKYARNEVYTL.VPPFA......EPKPGRENPTITPIPGDVVYFGFEAWEI..GNPAYGYDedseah.sdqgatdLAIFYGRNNLLINGDAGWVPGNVFAT.I.EEGLAEMAAAAQDLWLRGVEGETLSFAR.....................................................................
B9JL19_AGRRK/3-137                  ......lkitag------PFEFDAVLETAKAPKTSEVFLKQM...PFEGKIVHVRWSGEGVWIP.LGDLD......-FGVGYENHTSHPAPGHIILY-------..--PGGISE..............TEILLAYGGVDFSSKMGQLAGNHFIT.V.TSNLDKLPELGRLTLWEGAQSIRFET--ve...................................................................
C7MX78_SACVD/7-164                  ............ITLDKRGVSCRARLLDDEAPRTCQAVWDAL...PQSGAAYHAKYARNEIYTL.VPPFA......DPKPGRENPTVTPIPGDVVYFGFEAWEI..GNPAYGYDegseay.sengatdLALFYGRNNLLINGDAGWVPGNVFAT.I.TEGLEDMAAAAQDLWLRGVEGETLTFAR.....................................................................
A0A0C5L3Q3_9SPHN/7-159              .........vep----RSGLSARCQLLDEAAPESCAFLWDLAs.rGAGFEAMHAIWTGPEISVP.MPASTlptgmaAPAIPFENATSYPDAGDIVLAYLGAGSTkgLPPGAFYD..............IGIFYGSGGRLL-MPFGWIQANVCARiL.PEDLAKAQADCRSIRRSGACTLSLE---ta...................................................................
A0JVT3_ARTS2/7-164                  ............ITLEKRGVTCKALLLDDVAPRTSKAVWDAL...PQSSQVFHGKYARNEIYNL.VPAFA......PKEPGAENTTVTPIPGDVCYFTFTSNDL..KTPSHGYEadsgtd.evqtivdLAVFYGRNNLLLNGDTGWVPGNVFAT.I.VEGLDEMAAACQDIWMGGARDETLTFSR.....................................................................
#=GR A0JVT3_ARTS2/7-164       SS    ............EE-TTTSHHHHHHHHHH--EEEE-EE-SSS...EEEEEE--SSS---S-SEE.S--TT......EEHHHHSSTTT------------EEEEE..E-SSS---EETTTE.--EEEEEEEEESHHHHHHHHHHHHHH--TT-EE.E.EXXXXXXXXXXXXXXXXXXXXXXXXXXX.....................................................................
Q1LM09_RALME/4-136                  .........lri---SAAGYTFIADTNP-DAPQTVAAFLKLL...PYRQKLIHVRWSGEGCWIP.LGEFR......-LGVDFENHTSHPSVGDILFY-------..--PGGYSE..............TEIILAYGSCCFASKLGQLAGNHFLT.I.VEGKENLRALGTKVLWEGAQDVVFE---la...................................................................
G2IVD6_PSEUL/4-137                  ...........l-SIDVGSYRFVARLEEEAAPRTCAAFLKLL...PFSNQVIHSRWSGEAVWVP.LGDFD......-TGLGFENHTSHPSRGDLLLY-------..--PGGFSE..............TEILFAYGSSQFASKMGQLAGNHFLT.V.VEGADQLMDMGRTVLWKGAQPIRFT---dl...................................................................
M1XTJ2_NATM8/2-137                  ............IELDIDGTTLTAELHEDRAPRSVAAVREFL...PLESELMHVRWSGIATWIN.IDEIE......LPEIPRENHTVYPSRGDLLLY-------..--PGYRNE..............QEILLACGPTCFKSPAGELAGNHVAS.V.DATAEELKAIEETTLRDGVQDVTIRE--ve...................................................................
H6R413_NOCCG/7-163                  ............ITLTKAGVTCRARLLDAEAPLTCAAVWDAL...PQTGDAYHAKYARNEVYTL.VPRIT......-AAPHRENPTVTPIPGDVCLFDFEPWEI..GNPAYGYEpgstah.qgqgatdLAIFYGRNNLLINGDLGWVPGNVFAT.I.DDGLAEIAAACNDLWRYGVEGETLAFAR.....................................................................
D1C922_SPHTD/4-138                  ..........vr--ITVGSLEFVAQWEEEAAPKTCAAFRELL...PFQSKLIQARWSGESAWVP.LGDFQ......-LGVGFENATSYPAPGEILFY-------..--PGGYSE..............TEILVPYGPTCFASKLGQLAGNHFLT.I.VEGRERLPELGRLVVWEGAQDITFTA--md...................................................................
D0L4M4_GORB4/8-164                  ............VTLETRGVTATARLLDDEAPRTAGVVWDAL...PLGGQVYHGKFARNEIYTL.LPSFA......ATEPGPENTTVTPIPGDLCYFTFDG-VL..DNPAYGYQpdsapa.ehrllidLAVFYGRNNLLINGDVGWVPGNVFAT.I.TEGLDAFATACNDIWMGGARGEKLSYAR.....................................................................
C8X321_DESRD/38-170                 ..........mn--IEIDGHIFRADFEDQKSPETCKAFRKAM...PFVGNIVHVRWSGEGVWIP.LGSMD......-FSLGYEDATSYPSPGQILLY-------..--PKGKSE..............TEILIAYGCVHFASKAGVLAGNHFAT.I.TNQLEKLREIGISTLWEGTKSIKF----va...................................................................
W5TLN4_9NOCA/7-163                  ............ITLTKAGVRARARLLDDLAPHTCAAVWDAL...PQEGDAFHAKYARNEVYTL.VPRIT......-AAPHRENPTVTPIPGDVCLFDFEPWEI..GNPAYGYEpgsaah.daqgatdLALFYDRNNLLINGDMGWVPGNVFAT.I.ETGLPELATACNALWLRGVEGETLSFTR.....................................................................
D3F583_CONWI/28-159                 ...vvlewegga---------SEGVLFDEGAPRTVAAIAERL...PLEIPVIHAIWSGD-IVMS.AERFP......LGFQDKENETRLPRVGDLSWD-------..--P-TFGE..............VAVTYGTAECRM--PSGFNTIVVFGS.L.STSLDELARWCRRRRFEGLGQLRLDH--ar...................................................................
Q13WR5_BURXL/7-139                  .........iaw---PQLNVKVVAELNDERNPELCEEFWQQL...PFKVTQAHPVVSGASMYAW.TPVVS.....sAPVHHRELITECPI-GRLRYSQSTGNKM.sVQYGKGQE..............--------------------------.-.----------------------------plaqpvlgqvlpeychllpgvgkavwnnlfyekdviflevsa...........................
J7L2H7_NOCAA/7-161                  ............VTLARRGVSCVAELLDEDAPRTCEAVWNAL...PQGDAVQHAKYARNEVYTM.VPRFA......DPEPGQENPTVTPIPGDIVYFSFDSGML..DRSFK--Edkgidh..lpgvidLALFYGRNNLLLNGDVGWVPGNVFAT.V.VENLPAMAEACNDVWRSGSVGERLLYE-r....................................................................
A0A089YV92_9PSED/4-141              ...........i-KITSGGYEFLAETHPD-APQTVEAFLKLL...PYRQKIIHVRWSGEACWVP.LGEFQll..rdDAPVGFENHTSHPSVGDVLFY-------..--PGPYSE..............TEILLAYGSCCFASKMGQLAGNHFLT.V.VQGKENLRALGVKTLWEGAQEVLFE---la...................................................................
K0F3E7_9NOCA/7-163                  ............ITLTKAAVTCRARLLDAEAPHTCAAVWDAL...PQEGDAFHAKYARNEVYTL.VPRIS......-AAPHRENPTVTPIPGDVCLFDFEAWEI..GNPAYGYEpgstah.hdqgatdLAIFYGRNNLLINGDMGWVPGNVFAT.I.EEGLADIAAACNDLWLHGVSGETLAFAR.....................................................................
D8MR05_ERWBE/5-99                   ......mtvade-------KVCVIEVWDDKVPNLCNVLREKL...PMKSILQHGKLIGDMVFFT.MPIVA......----PWENKYKTEDV-------------..--------..............--------------------------.-.----------------------------gklrreqygkvtgavcyysprqqfcvvygdd......................................
B2JLB6_BURP8/4-138                  .....ilvdagp-------FRFVGQLEEQKAPRTCQRFLQLL...PFKNKVIHSRWSGEAVWIP.LGDFD......-TGLPFENHTSHASRGDVLFY-------..--PGGFSE..............TELLFVYGSSIFASKMGQLAGNHFFT.L.TEGHEHLEAFGKLVLWEGAQDITFSL--ln...................................................................
U7Q035_SPOS1/7-141                  ......llvttg------PYRFLARFESDAAPKTVAMFRTLL...PYRQKLIHVRWSGESLWVP.LGDQD......-LGINFENQTSHPAPGHILVY-------..--PGGYSE..............TELLFPYGGVQFASKMGQLAGNHFLT.I.VAGHEHLRPLGESVLWKGAQDVSFEV--ad...................................................................
A0A023X2C9_9ACTN/4-137              ........vrit----AGPYEFLARWERERCPKTCEAFERLL...PYRQKIIHVRWSGESCWIP.LGDYD......-LGVGFEDATSYPQAGEILFY-------..--PGGYSE..............TEILFPYYGTHFKSKLGTLAGNHLLT.I.TSGHENLRPLGEMTLWEGAQDITFEL--a....................................................................
A0A0D4DT93_9ACTN/21-178             ............VSLDKRGVSCTAKLLDDRAPMTCNAVWDAL...PLGGDVYHAKYARNEIYAL.VPPFA......PQEPPLENPTITPIPGDLCYFTFSETQL..ATASYGYEqdakhq.grttvvdLALFYERNNLLINGDAGWVPGIVWGA.V.VDGLDRMADACQDLWRAGALGETLNFRR.....................................................................
B6QPT5_PENMQ/8-140                  litagpyqflat--------------FESDAPKTNALFRSLL...PYHQKLIHVRWSGEGLWIP.LGETK......-FGVSYENHTSHPSAGQILLY-------..--PGGISE..............TEFLFCYGGVSFASKMGSLAANHFLT.V.KEGNENLKALGELVLWKGAQDVVFEV--ad...................................................................
Q1AS70_RUBXD/4-137                  .........vri---TVGPYEFLARWEGERCPKTCEAFERLL...PYRQKIIHVRWSGEACWVP.LGDYD......-LGVGFEDATSVPQAGEILFY-------..--PGGYSE..............TEILFPYYGTVFRSKLGVIAGNHLLT.V.TEGHENLRPMGEKCLWEGAQDILF----eka..................................................................
V6K3J1_STRNV/8-165                  ............VSLDKRGVRCTAKLLDELAPITCAAVWDAL...PLGGDVYHAKYARNEIYAL.MPGFA......AEEPPLENPTVTPIPGDLCYFTFSDTVL..GTTSYGYEeqaahr.grrtvvdLALFYERNNLLINGDTGWIPGIVWGS.V.VEGLDEMAEACQDLWRAGAVGETLNFRR.....................................................................
A0A0D5LLI2_9RHIZ/8-156              .......lkfid-----ADVTGIISLYWDNAPETCKAIWGALe.kPIQWPATHAIFSGPEIMMG.LPEEArn..fdPTKLPPENQTILPEPGELLWFYQPKNFF.kIDPDEFWE..............IGMFYGVGGRTF-GPTGWISCTYFGK.M.TENLEAVAAQCRLIRTEGAKRVEI----gr...................................................................
Q881W0_PSESM/4-141                  ikitaggyefla-------------VANPDAPQTVEAFLKLL...PYRQKFIHVRWSGEGCWVP.LDDYQlk..ldDKLIGFENATSHPSVGDILFY-------..--PGGYSE..............TEIILAYGSCCFASKMGQLAGNHFLT.I.TEGKENLRKLGVKTLWEGAQDVVFE---la...................................................................
B9LWF6_HALLT/2-137                  ...........l-EIEIDNTTFTAELHEDHAPDSVAAVRDFL...PLTSELMHVRWSGIATWIN.IDEIE......LPEVPRENHTVYPSRGDLLLY-------..--PGYCNE..............QEILVPCGPTCFKSPAGELAGNHFAT.I.DATAEELKQIEESTLRDGVLDVTIRE--va...................................................................
A0A0B4X1K7_9RHIZ/4-137              ..........lk--ISVASQVFVAKLEVEKAPKTCTAFTSLL...PFRNQTIHSRWSGEAIWVP.LGDYQ......-FGVDFENHTCHPSRGDILLY-------..--PGGHSE..............TELLFAYGSSSFASKMGALAGNHFLT.I.VEGCEQLDDMGKLVLWKGAQPILF----eal..................................................................
Q82CV7_STRAW/8-161                  ............VALDKRAVRCTARLLDDRAPLTCQAVWDAL...PLGSDVYHAKYARNEVYAL.FPPFA......AQEPPLENPTVTPIPGDLCYFTFSGAEL..GTKAYGYGkaqq.....etvvdLALFYERNNLLLNGDVGWVPGIVWGQ.V.VEGLDAMAEACNDLWRSGAQGETLSFRR.....................................................................
S5URS4_STRCU/8-163                  ............VSLDRRNTHCTARLLDDRAPLTCAAVWEAL...PLGGDVYHAKYARNEIYAL.FPPLA......STEPPLENPTVTPIPGDLCYFSFAGAEL..GTRAYGYDrevgs...gatvvdLALFYERNNLLLNGDVGWVPGIVWGQ.V.VSGLEEMAEACNDLWRTGAAGETLSFRR.....................................................................
Q93J70_STRCO/11-166                 ............VSLVKRGITCTAQLLDDRAPITCAAVWDAL...PLGGDVYHAKYARNEIYAL.FPPFA......TSEPPLENPTVTPIPGDLCYFAFAGAEL..GTKAYGYDrevrp...gttlvdLALFYERNNLLLNGDVGWVPGTVWGR.I.TEGLDTMAEACNDLWRTGAAGETLSFRR.....................................................................
V4IVH7_9ACTN/8-166                  ............ISLPKRGVHCTARLLDDKAPVTCAAVWEAL...PLSGDVYHAKYARNEVYAL.FEPFA......AQEPPLENPTVTPIPGDLCYFTFNGTQL..GNRAYGYDttgadvragatlvdLALFYERNNLLINGDMGWIPGIVWGT.V.VDGLDEMAAACNDLWRAGALGEALSFRR.....................................................................
A0QV99_MYCS2/7-164                  ............VSLDKRGVSCVARLLDEVAPRTCAAVWDAL...PLSAQVFHGKYARNEIYTL.LPAFA......PADPGKENTTITPIPGDLCWFSFDSDDL..GNPAYGYEnttgtg.ttggivdLALFYGRNNLLINGDQGWVPGNVFGT.I.VEGLDEMAEACQDLWMGGVRGETLSFSR.....................................................................
Q89H30_BRADU/4-137                  .........lvi---RAGDYTFDARFEEQLAPKTVAAFRKAM...PFESHIIHVRWSGEAVWMP.LGDLD......-FGVGYENHTSYPAPGQIILY-------..--PGGISE..............TEILMAYGGVSFASKMGQLAGNHFIT.V.TSGLENLATLGKSVLWKGALPIRFE---ev...................................................................
Q24P94_DESHY/4-138                  ...........i-KMTSGDFTFLVQMEEEKAPQTCEWFLNLL...PFKAQMIQARWSGQSTFIG.LKDLG......-ADVPYENPTSHPSKGEILMY--PGKEL..------SN..............GEILIPYGGTCFACPRGQISGNHFLT.I.IEGNSQLAELGRKTLYEGAQEIIF----ekv..................................................................
D7B049_NOCDD/3-157                  ............ITLPRRGVSCVAELLDKDAPRTCEAVWNAL...PQGDAVQHAKYARNEVYTM.VPRFA......EDEPGQENPTVTPIPGDVVYFSFDGGML..DRA--FKEdkgigh..lpgvidLALFYGRNNLLLNGDVGWVPGNVFAT.V.VENLPAMAEACNDVWRSGSVGERLVYER.....................................................................
V9XKL5_9NOCA/7-163                  ............ITLDKRDITCRARLLEDEAPLTCAAVWEAL...PQSGSAFHAKYARNELYTL.VPRIT......-AAPHRENPTVTPIPGDVCLFDFEPWEI..GNPAYGYEpgsqah.aqqgatdLALFYGRNNLLLNGDVGWVPGNVFAT.I.EEGLPELAVACNDLWIQGVVGETLSFAR.....................................................................
V6JZW3_STRRC/8-163                  ............VSLDKRDVHCTARLLTDRAPLTCEVVWQAL...PLAGDVYHAKYARNEIYAL.FPPFA......STEPPLENPTVTPIPGDLCYFSFAGAEL..GTKAYGYDrevrp...gttvvdLALFYERNNLLLNGDVGWVPGIVWGQ.V.VEGLEVMAEACNDLWRAGAAGETLSFRR.....................................................................
L2FC62_COLGN/10-131                 ..tagpyqflaa--------------FESAAPKTVAVFRNLL...PYGQQLIHVRWSGEAVWVP.LGEQD......-FSLGFENHTSHPGAGQILFY-------..--PGGYSE..............TELLFCYGGVSFASKMGSLSANHFLT.I.IEGAENLRALG-----------------eldqriqa.............................................................
A4FG67_SACEN/7-161                  ............ITLEKRGVSCVAELLDKDAPRTCEVVWQAL...PQAGPVHHAKYARNEIYTM.VPHFA......AQEPGQENPTVTPIPGDVVYFSFHGGML..DREFK--Eekdihe..lpgvidLAIFYGRNNLLLNGDVGWVPGNVYAT.I.VEGLDRMAEACNDVWRSGSVGERLVYDR.....................................................................
W0AED6_9SPHN/6-159                  ..........ft--EPGSGLDARCELLDAAAPASCNFLWSLAe.rNARFDAMHAIWTGPEISVP.MPSAAlpegmdQPAIPAENATSYPDTGDIVLAYLAAGSTrgLPPGNFYD..............IGVFYGPGGRLL-MPFGWIQANVCARiL.PEDLAKAQADCRTIRRNGACTFSIE---lg...................................................................
F4CME6_PSEUX/22-178                 ............ITLAKRGVSCVAELLEKEAPRTSAAVWEALgrgDLGGDAQHAKYARNEVYTM.VPRFG......-DEIGYENTTVTPIPGDVVYFSFSGGML..DQSFKADQnidhl....pgvidLAIFYGRNNLLLNGDVGWVPGNVYAT.I.VEGLDVMAEACHDVWRSGSVGERLVYSR.....................................................................
L0K3G5_9EURY/4-138                  ............LTIDVADYAFEADVFEEKAPESVEAMREFL...PLESTLMHVRYSGIATWIN.IDEIE......LPNLPRENHTAYPSRGDVLLY-------..--PGYRNE..............QEILVACGPTRFSSPAGELAGNHVAT.I.DASAETLKELEERTLHEGAFDVTLSM--r....................................................................
H5X7Z0_9PSEU/7-164                  ............ISLDKRGVSCRARLLEDEAPRTCRAVWDAL...PQSGSAYHAKYARNEVYTL.LRPFA......DPQPGRENPTVTPIPGDVVYFGFEAWEI..GNPAYGYEegsaah.geqgatdLAIFYGRNNLLINGDAGWVPGNVFAT.I.VEGLPEMAEAAQDLWLRGVEGETLTFAR.....................................................................
D4GPV2_HALVD/2-137                  ...........l-QLEIGDRTFTAELHEDRAPASVEAVREFL...PLESELMHVRWSGIATWIN.IDEID......LPEIPRENHTVYPSRGDLLLY-------..--PGYRNE..............QEILVPCGPTCFKSPAGELAGNHFAT.I.DATAEELKAIEELTLREGVQDVVIR---evs..................................................................
F5YYE8_MYCSD/7-162                  ............ITLTSRGVSCRARLLEDAAPRTCAVVWNAL...PVAGQAYHGKYARNEVYTL.LPPMG......--APGRENTTVTPIPGDVCFFSFEPGDI..GNPAYGYDegaqgn.spvgatdLAIFYGRNNLLLNGDVGWVPGNVFAT.I.EDGLAEMAAACNDLWMAGAVGEQLAFSR.....................................................................
C4ZM00_THASP/4-137                  ..........la--IDVGPFRFVARMEEAAAPKTCAAFLELL...PFSNQVIHSRWSGEAVWVP.LGEFD......-TGLGFENHTSHPSRGDILLY-------..--PGGLSE..............TEILFAYGSSCFASKMGQLAGNHFLS.V.VEGAEQLHEMGRTVLWKGAQWIRFT---dl...................................................................
I1D5M9_9PSEU/7-164                  ............ISLDKRGVSCRARLLDAEAPRTCRAVWDAL...PRSGAAYHAKYARNEVYTL.LPPFA......DPEPGRENPTVTPIPGDVVYFGFEAWEI..GNPAYGYDeasaah.nargatdLAIFYGRNNLLLNGDVGWVPGNVFAT.I.TEGLEEMAEAARDLWLRGVEGETLTFAR.....................................................................
Q0S805_RHOJR/7-163                  ............ISLDKRGVTCRARLLDEDAPLTCDAVWNVL...PQSGDAYHAKYARNEVYTL.IPRIT......-AAPRRENPTVTPIPGDVCLFDFEPWEI..GNSAYGYEpgseah.aaqgatdLAIFYGRNNLLLNGDVGWVPGNVFAA.I.EEGLPELAAACNDLWMRGVEGETMSFAR.....................................................................
E8TB59_MESCW/6-159                  ............ITEPRSQLSVTALLLPEKAPENAAFLLAYLg.tPRVVPGIHAMWTGPEISCP.VPSADlegqayAKPLPAENATLNPQPGDIVLSYVPPRMW.gGNPNAIFD..............IGLYYGQGARLL-FPIGWLAGSVVAQ.VrVEERDRFAAACGVIRRNGACDVTFSL--me...................................................................
G2NX92_STRVO/11-168                 ............VSLEKRGVSCTAKLLDERAPITCEAVWNAL...PLGGDVYHAKYARNEIYAL.LPPFA......PEEPPLENPTITPIPGDLCYFTFTDTQL..GTTSYGYEtdanhq.grrqvvdLALFYERNNLLINGDAGWVPGIVWGS.V.VDGLDRMADACQDLWRAGALGETLSFRR.....................................................................
A0A0A1DG62_NOCSI/12-160             .......lefdn------GARAVATLADDVAPKTAEALWSALa.ePVTETVMHAMYAGPEVMFG.LPESAqn..fdPAALPAENQQVIPAAGDLIFYHQIPHQM.sGLDFELWE..............VGIFYGKGGRIF-GPLGWTPCSIFAS.I.TEGLDEFAAACQETRVSGVKSLTI----grv..................................................................
W0I349_9ENTR/9-126                  ......fdvpdl------DIQFRARLLREQNPDVVEQVLAQL...PLKSVLGHVVVSGEAIWMP.TRIVH......---LGRSNM-VQRSPGAVYLY-------..--------..............--------------------------.-.----------------------------apgqticltygritesatvnqfaevpaedlaqlekvgtyvwentval......................
A0A0A2L0B1_PENEN/4-137              .....vlitagp-------YKFRAR-FESSAPKTVALFRTLL...PYRQKLIHVRWSGEGLWIP.LGETD......-FGVPFENHTAHPAPGQILLY-------..--PGGISE..............TEFLFCYGGVAFASKMGPLAANHFLT.I.IEGNENLKALGELVLWKGAQDILFE---ldd..................................................................
F2J3Z8_POLGS/8-157                  ........lkfv----EADVQGIISLYWDNAPETCKAIWGALe.kPIRWPATHAMFSGPEIMMG.LPEEArn..fdPTALPPENQTVLPEVGEVLWFYQPKNFF.kIDPSEFWE..............IGLFYGVGGRTF-GPTGWIPCTYFGR.M.THNLDAVAEQCRLIRTEGAKVVEI----grv..................................................................
#=GC SS_cons                        ............EE-TTTSHHHHHHHHHH--EEEE-EE-SSS...EEEEEE--SSS---S-SEE.S--TT......EEHHHHSSTTT------------EEEEE..E-SSS---EETTTE.--EEEEEEEEESHHHHHHHHHHHHHH--TT-EE.E.EXXXXXXXXXXXXXXXXXXXXXXXXXXX.....................................................................
#=GC seq_cons                       ................htshphhAcLh--cAPcTstAhhchL...PhpsplhHu+autptlas..lsphs........tsshENtTspP.sGDllha...........Puhh.E..............htlhashsshhhsuchG.lsGNhFhT.l.sEGh-phtthspplhhpGAps.shp........................................................................
//
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