#=GF ID   DUF3845
#=GF AC   PF12956.11
#=GF DE   Domain of Unknown Function with PDB structure
#=GF AU   Ellrott K;0000-0002-6573-5900
#=GF SE   JCSG structure PDB:3GF6
#=GF GA   25.00 25.00;
#=GF TC   225.10 225.00;
#=GF NC   23.10 20.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF CL   CL0100
#=GF RN   [1]
#=GF RM   20346680
#=GF RT   The molecular regulation of programmed necrotic cell injury.
#=GF RA   Moquin D, Chan FK
#=GF RL   Trends Biochem Sci. 2010 Mar 24
#=GF RN   [2]
#=GF RM   20152153
#=GF RT   A TNF-like trimeric lectin domain from Burkholderia cenocepacia
#=GF RT   with specificity for fucosylated human histo-blood group
#=GF RT   antigens.
#=GF RA   Sulák O, Cioci G, Delia M, Lahmann M, Varrot A, Imberty A,
#=GF RA   Wimmerová M.
#=GF RL   Structure. 2010 Jan 13;18(1):59-72
#=GF DR   INTERPRO; IPR024328;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   Member PDB:3GF6 has statistically significant similarity  to
#=GF CC   TNF-like jelly roll fold may indicate an immunomodulatory 
#=GF CC   function[1] or a bioadhesion role[2]
#=GF SQ   9
#=GS R6D787_9BACE/1-240      AC R6D787.1
#=GS A0A3L7Z148_9BACE/1-240  AC A0A3L7Z148.1
#=GS A0A1M5BST7_9BACE/1-241  AC A0A1M5BST7.1
#=GS A0A173XAV5_9BACE/1-240  AC A0A173XAV5.1
#=GS U6RLZ6_9BACT/1-238      AC U6RLZ6.1
#=GS A0A174Q6G6_9BACE/2-242  AC A0A174Q6G6.1
#=GS Q8A8D4_BACTN/3-242      AC Q8A8D4.1
#=GS W4UU93_9BACE/1-239      AC W4UU93.1
#=GS E5C7K1_9BACE/3-242      AC E5C7K1.1
R6D787_9BACE/1-240                 MDKIIGVAVLLLCLYGCAKDNDAIYYPVGNVNVENGDPALEDGKGE-LVARSYNDEDYVLDTIAQYPGDPTLGKLTFMVNLKNQLAGKEAEGFNGIGKSGLTMSLGYKNGNYPQESQIPVYTSSDVTTAYAVKLRLKGELTLSGGEWMIDYVYAQLASLFQPYPPTAFP.EVFMCKGGEQsFAYFDSFRRTWTFDIEYNRSNLSFSQLYFNLFVNLAGQKREDRVRLRIDKDSYFEIYKL--ke
A0A3L7Z148_9BACE/1-240             MNKIIRLAVLLLCFCSCAIDNDAIYYPVGNVDVENGGPALEDGKGE-LVARSYNTEDYVLDTVAQYPGNPTLGKLTFMVNLKNQLAGQEANGFNGIGTSGLTMSLGYKDGNYPEESQVPVYASPDVTTAYAVKLRLKGELTLSGDDWMIDFVYVQLASLFQPYPPASFP.EVFMCKGGEQsFACFDSFRRTWTFDIEYNRSNLFFSQLYFNLFVNLAGQKREDRIRLRIDKESFFEIYKL--ee
A0A1M5BST7_9BACE/1-241             MKKIIEMAVLLLCLYGCAKDNDAIYYPISNVDIETGGPALIVEEGQVPLIRSYNDEDYVLDTVAQYPNNPTLGKLTFMIDLKNQLADEEVVGFNGVGKSKLTMSLGYKDGNYSAISQVPIYTSLDVTTRYAVKLRLKGELALSGDEWMIDYVYTQLASLFQPYPPSSFPaEVFMCKGGMK.FGTFDPFRRTCTFDISYDRSDLSFSQLYFNMFINLAGQKREDRIRLRIDKESFFEVYEQKE..
A0A173XAV5_9BACE/1-240             MNKIIGLAVLLLCVCGCAKDDDAIYYPVGNVDIERGDVALEDGKGE-LVAGSYNEEDYVLDTLAQYPGDPTLGKLTFMIDLKNQLARQEAGGFNGIGKSGLTMSLGYKNGDYPSESQIPVYTSPDVTAAYAVKLRLKGELALAGDEWMIDYIYVQLAGLFQPYPPASFP.EVFMCKGGEQpFAAFDSFRRTWTFDITYSRSGLSFSQLYFNLFLNLAGQKREERIRLRIDKESFFEVYKL--ne
U6RLZ6_9BACT/1-238                 MNKFIVFLLCALFFGSCNEEEDSIYYPLDNVDIIKGGSEEPTG-NATLIAESHNLESYVLDTLAVYPYDKTIGKLTFKFDPKNAVSDVTMEGFRGEGKSEMGMSNSYYDGNFPEEYRQPIFMNDNPAKKYRIKFRLKGEFRYYTEHWYTDYIYMMLSASFLPYPPAVSE.DVFLCKSNEA.FAELNTAERLYTFDVQYDRWNLSFTELYLNIFVNLIGQKESEKVSLSIDKESFFEIYE---in
A0A174Q6G6_9BACE/2-242             MNKIIGAAVLLLCFCSCVKDNDAIYYPVGNVDIEKGGPALEVGSNSILVAESYNEEDYVLDTLAQYPGDPTLGKLTFMINLKNQSGTREVAEFNGVGKSVLTMSLGYKDGNYPVESQIPVYTSADATASYAIKLRLKGELTLTDDEWMIDYVYAQLAGLFQPYPPASFP.EVFMCKGGEQsFATFDSFRRTWTFDITYDHSELSFSQLYFNLFVNLAGQKREDRIRLRIDKDSYFKIYKI--ke
Q8A8D4_BACTN/3-242                 MNKIVGMAALLLCLTGCVRDNDAIYYPVGDVDIERGGPALEVGEEDVLVARSFNEEDYVLDTIAQYPNDPTLGKLTFMIDLKNQQKDQNVADFNGVGKSKLTMSLGYKDGNYPSESQVPIYTSQDVTAKYAVKLRLKGELLVSGDEWMIDYVYAQLASLFQPYPPANFP.EVFMCKGGMK.LGTFDSFRRTCTFDITYDRSDLSFSQLYFNLFINLAGQKRENRVRLRIDKESYFELYEQSE..
W4UU93_9BACE/1-239                 MSKIILFVGLLCCFCSCVRDNDAIYYPVGNIDIERGNANLSETSEATLIARSANLDDYVLDTLAGYPGDPTIGKLTFMFNLKNQQRDVSVEGFDGVGETQMNMSLGYKDGDFAAENQLPVFA-TDIAGKYAVKLRLKGTLLLKGDAWIVDYAYAQLASAFHLYPPATQT.EVFMCKGGSA.FGTFDSARRTCTFDITYERYDLSFSQLYFNLFVNLSGQESEENIQLRIDKESYLEIYKQQE..
E5C7K1_9BACE/3-242                 MNKIIGLAVLLFCLSGCVRDNDAIYYPVGNVDVERGGPALEAGKGD-LIARSYNTEDYVLDTLAQYPGDPTLGKLTFMVSLKNRLADQEVSGFNGVGLSKLTMSLGYKDGNYPAESQVPVYTSSDVTASYAIKLRLKGELTLTGDEWMIDYIYAQLAGLFQPYPPTSFP.EVFMCKGGEQsYATFDSFRRTWTFDITYDRSNLSFSQLYFNLFVNLAGQKREDRVRLRIDKESYFEIYKE--kr
#=GC seq_cons                      MNKIIshAVLLLChsuCs+DNDAIYYPVGNVDIE+GGPALEsGcsp.LlARSYNpEDYVLDTlAQYPGDPTLGKLTFMlsLKNQlucpEssGFNGlGKStLTMSLGYKDGNYPsESQlPVYTSsDVTspYAVKLRLKGELsLoGDEWMIDYlYsQLAuLFQPYPPAoFP.EVFMCKGGEp.FAsFDSFRRTaTFDIoY-RSsLSFSQLYFNLFVNLAGQKRE-RlRLRIDKESaFEIYK....p
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