GenomeNet

Database: Pfam
Entry: DUF3850
LinkDB: DUF3850
Original site: DUF3850 
#=GF ID   DUF3850
#=GF AC   PF12961.5
#=GF DE   Domain of Unknown Function with PDB structure (DUF3850)
#=GF AU   Ellrott K
#=GF SE   JCSG structure PDB:3IUW
#=GF GA   30.00 29.00;
#=GF TC   31.00 35.20;
#=GF NC   29.80 28.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   16322048
#=GF RT   The ASCH superfamily: novel domains with a fold related to the
#=GF RT   PUA domain and a potential role in RNA metabolism. 
#=GF RA   Iyer LM, Burroughs AM, Aravind L; 
#=GF RL   Bioinformatics. 2005; [Epub ahead of print]DR   SCOP; 88697;
#=GF CC   The search results from NCBI sequence alignment indicates a
#=GF CC   conserved domain belonging to ASCH superfamily [1]. Dali
#=GF CC   searching results show that the protein is a structurally
#=GF CC   similar to the PUA domain, suggesting it may be involved in RNA
#=GF CC   recognition. It has been reported that the deletion of PUA genes
#=GF CC   results in impaired growth (RluD) and competitive disadvantage
#=GF CC   (TruB) in Escherichia coli.  Suggestions have been put forward
#=GF CC   that, apart from their usual catalytic role, certain PUS enzymes
#=GF CC   (e.g. TruB) may also act as chaperones for RNA folding. The
#=GF CC   interface interaction indicates that the biomolecule of protein
#=GF CC   NP_809782.1 should be a dimer.
#=GF SQ   111
#=GS A0A0G1T533_9BACT/6-75    AC A0A0G1T533.1
#=GS A2SN47_METPP/13-94       AC A2SN47.1
#=GS R7BMW7_9FIRM/17-92       AC R7BMW7.1
#=GS A0A0G1AFY2_9BACT/4-70    AC A0A0G1AFY2.1
#=GS A0A0C5W887_9FLAO/4-77    AC A0A0C5W887.1
#=GS A0A0G0RZQ4_9BACT/4-75    AC A0A0G0RZQ4.1
#=GS A0A0G0QJ90_9BACT/5-84    AC A0A0G0QJ90.1
#=GS L7U3C0_MYXSD/4-79        AC L7U3C0.1
#=GS A0A0M9GE41_9PSED/20-93   AC A0A0M9GE41.1
#=GS K8EIC3_CARML/4-76        AC K8EIC3.2
#=GS T1ZGV5_STRIT/3-75        AC T1ZGV5.1
#=GS A0A0G0CIM6_9BACT/5-84    AC A0A0G0CIM6.1
#=GS J0N2B2_9CLOT/5-81        AC J0N2B2.1
#=GS K2B862_9BACT/4-73        AC K2B862.1
#=GS K2FRK8_9BACT/4-74        AC K2FRK8.1
#=GS A0A0G1NPX0_9BACT/5-71    AC A0A0G1NPX0.1
#=GS Q8CWZ2_STRMU/4-76        AC Q8CWZ2.1
#=GS A0A0G0KL88_9BACT/4-75    AC A0A0G0KL88.1
#=GS A0A0G1X7S3_9BACT/5-86    AC A0A0G1X7S3.1
#=GS A0A0G0NI66_9BACT/5-75    AC A0A0G0NI66.1
#=GS I3ILU1_9BACT/4-78        AC I3ILU1.1
#=GS W8FCI0_9BACT/21-96       AC W8FCI0.1
#=GS A7MEP6_CROS8/3-73        AC A7MEP6.1
#=GS A0A0G0IQT2_9BACT/5-87    AC A0A0G0IQT2.1
#=GS A8T494_9VIBR/5-79        AC A8T494.1
#=GS A0A0G0MRT2_9BACT/5-73    AC A0A0G0MRT2.1
#=GS A0A0G0FVZ0_9BACT/19-85   AC A0A0G0FVZ0.1
#=GS A0A0G1TGW2_9BACT/4-74    AC A0A0G1TGW2.1
#=GS A0A0G0QIE8_9BACT/16-87   AC A0A0G0QIE8.1
#=GS A0A0G0HWS4_9BACT/8-86    AC A0A0G0HWS4.1
#=GS A0A0G1TVJ2_9BACT/5-75    AC A0A0G1TVJ2.1
#=GS A8E2L6_BPPHE/105-175     AC A8E2L6.1
#=GS R9TBY5_9EURY/3-77        AC R9TBY5.1
#=GS D3UZP9_XENBS/15-94       AC D3UZP9.1
#=GS A8FAI2_BACP2/6-76        AC A8FAI2.1
#=GS A0A0G1NAE5_9BACT/5-47    AC A0A0G1NAE5.1
#=GS A0A0G0MX61_9BACT/5-74    AC A0A0G0MX61.1
#=GS M9SC14_9EURY/4-81        AC M9SC14.1
#=GS A0A0G0MDG0_9BACT/4-83    AC A0A0G0MDG0.1
#=GS W8FAL7_9BACT/20-95       AC W8FAL7.1
#=GS A0A0G0UQA7_9BACT/4-74    AC A0A0G0UQA7.1
#=GS A0A0G1DEZ4_9BACT/4-74    AC A0A0G1DEZ4.1
#=GS K8E4A8_CARML/4-76        AC K8E4A8.2
#=GS A0A0G0QDD6_9BACT/5-74    AC A0A0G0QDD6.1
#=GS A0A0G0XJX9_9BACT/1-71    AC A0A0G0XJX9.1
#=GS A0A0G1U561_9BACT/5-75    AC A0A0G1U561.1
#=GS A0A0G1PNJ1_9BACT/5-71    AC A0A0G1PNJ1.1
#=GS B2TNZ8_CLOBB/5-89        AC B2TNZ8.1
#=GS B0T870_CAUSK/4-79        AC B0T870.1
#=GS D4MVL8_ANAHA/411-483     AC D4MVL8.1
#=GS A0A0G0M7Q3_9BACT/4-84    AC A0A0G0M7Q3.1
#=GS R6T3D1_9FIRM/130-204     AC R6T3D1.1
#=GS A0A0D8Q9M7_9GAMM/12-90   AC A0A0D8Q9M7.1
#=GS A0A0G1XWZ5_9BACT/6-74    AC A0A0G1XWZ5.1
#=GS A0A0G0IIS8_9BACT/5-75    AC A0A0G0IIS8.1
#=GS W8TVL4_YEREN/55-128      AC W8TVL4.1
#=GS A0A0G0P9Y0_9BACT/11-78   AC A0A0G0P9Y0.1
#=GS K1XQT2_9BACT/5-72        AC K1XQT2.1
#=GS A0A0G0N686_9BACT/5-87    AC A0A0G0N686.1
#=GS J2H1A2_9CAUL/6-84        AC J2H1A2.1
#=GS K4Z9V6_PAEAL/3-77        AC K4Z9V6.1
#=GS K1ZBP3_9BACT/5-85        AC K1ZBP3.1
#=GS A0A0G1M1D1_9BACT/6-87    AC A0A0G1M1D1.1
#=GS R5Y974_9FIRM/3-77        AC R5Y974.1
#=GS A0A0G1UX10_9BACT/4-75    AC A0A0G1UX10.1
#=GS A0A0G1WL94_9BACT/6-77    AC A0A0G1WL94.1
#=GS R6TFC5_9FIRM/329-401     AC R6TFC5.1
#=GS G5KEM2_9STRE/9-82        AC G5KEM2.1
#=GS A0A0F4KNZ6_9LACO/4-76    AC A0A0F4KNZ6.1
#=GS R5F6I4_9CLOT/5-77        AC R5F6I4.1
#=GS G5K063_9STRE/4-79        AC G5K063.1
#=GS H1BNZ8_9FIRM/4-75        AC H1BNZ8.1
#=GS A0A0G1W247_9BACT/5-73    AC A0A0G1W247.1
#=GS A0A0G0S214_9BACT/1-50    AC A0A0G0S214.1
#=GS A0A0F5VF90_9GAMM/7-81    AC A0A0F5VF90.1
#=GS Q832V0_ENTFA/113-183     AC Q832V0.1
#=GS A0A0G0G4U8_9BACT/6-87    AC A0A0G0G4U8.1
#=GS A0A0G4B2Q2_9BACT/4-84    AC A0A0G4B2Q2.1
#=GS J1GZ79_9CLOT/5-81        AC J1GZ79.1
#=GS A0A0G0L2B8_9BACT/5-87    AC A0A0G0L2B8.1
#=GS A0A0G1NRI0_9BACT/5-72    AC A0A0G1NRI0.1
#=GS F0LNE9_VIBFN/7-81        AC F0LNE9.1
#=GS A0A0G1TEZ2_9BACT/5-72    AC A0A0G1TEZ2.1
#=GS A0A0G1CAE4_9BACT/5-71    AC A0A0G1CAE4.1
#=GS A0A0F5VH08_9GAMM/7-81    AC A0A0F5VH08.1
#=GS J9RHJ8_9ACTN/3-74        AC J9RHJ8.1
#=GS A0A0F9ZIZ5_9BACT/5-85    AC A0A0F9ZIZ5.1
#=GS A0A0G1D3N9_9BACT/6-73    AC A0A0G1D3N9.1
#=GS A0A0C5WXL1_NOCSI/4-98    AC A0A0C5WXL1.1
#=GS K6T5U5_9CLOT/3-77        AC K6T5U5.1
#=GS B2TRS1_CLOBB/5-89        AC B2TRS1.1
#=GS A0A0F9YJ86_9BACT/4-76    AC A0A0F9YJ86.1
#=GS A0A0F9YIJ9_9BACT/5-77    AC A0A0F9YIJ9.1
#=GS R5KJ01_9CLOT/4-86        AC R5KJ01.1
#=GS Q1A0P1_9CAUD/5-76        AC Q1A0P1.1
#=GS J2PVF6_9CAUL/4-79        AC J2PVF6.1
#=GS A0A0F9Z2S6_9BACT/5-76    AC A0A0F9Z2S6.1
#=GS A0A0G0GK40_9BACT/5-86    AC A0A0G0GK40.1
#=GS A6LYH9_CLOB8/3-77        AC A6LYH9.1
#=GS V4QTJ1_STRIN/4-79        AC V4QTJ1.1
#=GS A0A0G1YXM0_9BACT/5-85    AC A0A0G1YXM0.1
#=GS A0A0G0YKY0_9BACT/5-72    AC A0A0G0YKY0.1
#=GS A0A0G0C8X7_9BACT/5-86    AC A0A0G0C8X7.1
#=GS X2H0U5_9BACI/244-319     AC X2H0U5.1
#=GS R9TAF8_9EURY/14-88       AC R9TAF8.1
#=GS G7Q5K8_9DELT/5-88        AC G7Q5K8.1
#=GS A0A0G1WMJ8_9BACT/5-71    AC A0A0G1WMJ8.1
#=GS A0A0C1DXY3_9FLAO/3-76    AC A0A0C1DXY3.1
#=GS A0A0G1AJE3_9BACT/20-101  AC A0A0G1AJE3.1
#=GS R6E210_9FIRM/6-79        AC R6E210.1
#=GS A0A023CIU1_GEOSE/7-79    AC A0A023CIU1.1
A0A0G1T533_9BACT/6-75               hk---KIWPEFFE..KVLSGEKRFELRI.ADFEISPGDTLILEEWNQN.........TKS........YTGRRLIKNVGYILKSD........LD.-.-.......---------qfgqra...............
A2SN47_METPP/13-94                  ..HVLKTDPDAFD..SVARGLKTVEIRR.RDRDYRVGDTLLLLRTRFS........aS-EmatgqpldYSGDALAVLVTHIQT--........GY.E.L.......PDALCVMSI.....................
R7BMW7_9FIRM/17-92                  ..HKLKIKEDFAN..AIITGDKNFEIRK.NDRGFQRGDLIEFVVVDDKg.......vAHH........HEIDEYIYKINYVMN--........GY.G.L.......KNGYVVFGI.....................
A0A0G1AFY2_9BACT/4-70               ek---KVWPKYFQ..AILDGKKNYELRL.ADWECNVEDTLLLKEWNPE.........IKG........YTGREVSKKIKYVAK--........--.-.-.......---------fkiddlf..............
A0A0C5W887_9FLAO/4-77               ..HNLKTLPVYFN..RVWELEKQFEIRK.NDRGFQTGDKLRLEEWTE-.........KDG........YTQRFIECTVKYVLH-G........FE.G.L.......TDGYVALGI.....................
A0A0G0RZQ4_9BACT/4-75               ek---KILPEYFK..KVACGDKNFELRL.ADWECHPGDVLILREWDLK.........TKQ........YTGSSIEKEVTCVLKTK........--.-.-.......---------dqtffsdedv...........
A0A0G0QJ90_9BACT/5-84               ek---KAWSELFE..KVRTGEKTFDLRL.DDFRCKVGDILILREWNPK.........EKK........YTGRVLERKVTFVLKS-........--.-.-.......---------kdvlkfwseeeiakhgfqv..
L7U3C0_MYXSD/4-79                   ..HDLKTWPPYFQ..DVMTGVKSFELRE.NDRDFAVGDTLCLREWDPQ.........VSQ........YTMRAVTRRVVYVLPGG........AF.G.L.......ASTHVILGL.....................
A0A0M9GE41_9PSED/20-93              ..HELKIRQTPLA..DLLSGLKTGEIRDcSDREFAVGDTVLLREIDD-.........GRE........YTGTVARRTITHVQK--........HY.G.L.......PDHLCVLS-y....................
K8EIC3_CARML/4-76                   ..HELKIEPKYFE..AVKDGRKKFEIRK.NDRNFQEGDVLILKEYDPI.........TQL........FSGEAIEVEISYMPD--........-F.P.L.......KDGYVVLGI.....................
T1ZGV5_STRIT/3-75                   ..HEIKLSHLFFD..DVQSGKKNFELRR.DDRNYQVDDELLLNEIK--.........DGV........LTGRKIQVKVIYKLT-G........YV.G.L.......EPTYCILGI.....................
A0A0G0CIM6_9BACT/5-84               ek---KTQPYLFE..KVLSGDKQFDLRI.AEFECEVGDTLVLREWDPE.........KEE........YTGRELEKEITFVLKTK........--.-.-.......---------dlkfwsqedinelgflvm...
J0N2B2_9CLOT/5-81                   ..HELKIRPEYMH..DVCAGTKPFEVRK.DDRGYLTGDYLILREYVQQg.......aSGN........YTGREVKVAVTYILR-D........SC.Y.V.......RPGYVVMGI.....................
K2B862_9BACT/4-73                   ek---KTWPEYFQ..LILDGKKTYDLRM.ADFECREGDVLVLREWNPE.........TKE........YTGRILEKEVTFVGKI-........--.-.-.......---------ngmsfwkke............
K2FRK8_9BACT/4-74                   kk---KTWTEGFE..KILSGEKTFDARL.VNFECKPGDTLVLEEYDPA.........RRK........YTGRKIEKEISFVLDTK........K-.-.-.......---------qkywsqsd.............
A0A0G1NPX0_9BACT/5-71               kk---KAWPELFE..AVVSGKKKYDLRL.NEFEINEGDTLLLEEWDPK.........TKT........YTGRSVEKKAGHVWK--........--.-.-.......---------fkldklf..............
Q8CWZ2_STRMU/4-76                   ..HKIKLSHCFFD..DVASGRKNFELRK.NDRHYQVGDCLCLCEVK--.........EKR........LTGRKLMVAVTYKLQ-D........FT.G.L.......SDGYCILGI.....................
A0A0G0KL88_9BACT/4-75               ek---KILPEYFK..KVVSGDKKFELRL.ADWECNVGDILILREWDPT.........KKD........YTGASIEKEVSCLIKTK........--.-.-.......---------eqkfftdedv...........
A0A0G1X7S3_9BACT/5-86               kk---KIWPEYFE..AVVSGKKNFEVRL.ADFDVNEGDTLLLEEWDPG.........TKE........YTGRSVEKQVTYVAKTK........S-.-.-.......---------fafyqpeevekygyqvigl..
A0A0G0NI66_9BACT/5-75               kk---KAWQGYYE..QVVSGEKKFDMRV.ADFPVVAGDTLVLEEWNPE.........TKE........YTGRSISKKVGYVGT--........--.-.-.......---------fsldafgqrea..........
I3ILU1_9BACT/4-78                   ..HYLKCWPEYFQ..AILERKKTFDLRR.NDRDYKVGDILVLQEYDIK.........AER........YTGRSTCVGVEYILD-V........AD.G.L.......QRGYIIMSI.....................
W8FCI0_9BACT/21-96                  ..HELKVWPGCFA..AVEAGTKPFDVRL.NDRNFRVGDAVLLCEYEPE.........SEQ........FTGRTTERWVSYLLPGG........SF.G.I.......EAGWCVLGF.....................
A7MEP6_CROS8/3-73                   ..HHLKILPEHFI..PVLEGVKLAELRK.NDRNYQVGDILVLCEWN--.........-GE........YTGEACEREVVHVADVG........SY.-.-.......LPGYVLLSM.....................
A0A0G0IQT2_9BACT/5-87               ek---KAVPNLFE..KVKSGEKTFDVRL.NDFRCKVGDILVLREWDTK.........NKK........YTGRVLERKITFVLKSK........--.-.-.......---------dvlkfwseeeiakhgfqvigf
A8T494_9VIBR/5-79                   ..HVIKVQSEHFS..EVLAHRKTNEVRL.NDRDYQAGDCLNLREIDS-.........SGQ........ITGQEVNAEVSHVLQGG........QF.G.V.......AEGWCVLSL.....................
A0A0G0MRT2_9BACT/5-73               .k---KIWPKYFN..LVKSGKKKFEVRA.ADFKIREGDELILEEWNPK.........TKK........YTGRKLKKKAKYILKF-........--.-.-.......---------klnkfgqek............
A0A0G0FVZ0_9BACT/19-85              kk---KIWPEYFD..AVASGKKKFELRL.NDFEVNEGDTLKLEEWDPK.........TKV........YTGRKVLKKVTFVGK--........--.-.-.......---------fkinelf..............
A0A0G1TGW2_9BACT/4-74               ek---KTWPEYFQ..LILDGKKTYDMRL.ADFKCKEGDVLVLREWDPE.........TKE........YSGRVLEKEITYVGKTK........--.-.-.......---------kfdfwkked............
A0A0G0QIE8_9BACT/16-87              kk---KCWPEIFE..LVKSGKKKFDLRL.ADFDIQEGDTLVLEEWDPE.........TKK........YTGRNIKKKAEYVLKFD........--.-.-.......---------lnkfgqekei...........
A0A0G0HWS4_9BACT/8-86               ek---KVWPEYFQ..KILDGVKTYELRL.ADFQCNPGDTLVLQEWDPN.........TKE........YTGRKLEKTVTYVGKT-........--.-.-.......---------kdlsfwskeeieeygyqi...
A0A0G1TVJ2_9BACT/5-75               hk---KIWPEYFD..AVASGKKKYELRL.NDFEVKEGDMLVLEEWDPE.........TKK........YTGRSTEKKVTYVGK--........--.-.-.......---------lkidklfwpee..........
A8E2L6_BPPHE/105-175                ..HNLKIAPTYFK..AVKEGRKLFEIRK.NDRNYHVGDILLLNEYT--.........CGA........YTGEFIKVEVTYITD--........-Y.A.Q.......KDDYVVLGI.....................
R9TBY5_9EURY/3-77                   ..HELKIMPDYFE..AVVIGAKTFELIN.DDRGFQIRDILILKEWDPD.........AEE........FTGREVVRRICYVLK-R........VP.G.L.......TSGYAILGI.....................
D3UZP9_XENBS/15-94                  ..HSLIISGVHFNfmAVVDGDRKTAFVK.DDRDYKSGDFLALNEIDN-.........DGN........FTGSLMAARITDVAAIDk......nLYpQ.I.......AGEFVFLSF.....................
A8FAI2_BACP2/6-76                   ..HDLKIMPQYLW..AIKTGIKGFEIRK.NDREFQVGDILRLREYK--.........DGQ........YTGRLVLGRITFITS--........-F.E.Q.......KDDYVVLNF.....................
A0A0G1NAE5_9BACT/5-47               kk---KAWPELFE..AVVSGKKKYDLRL.NEFEINEGDVLALEEWDPE.........---........-----------------........--.-.-.......---------t....................
A0A0G0MX61_9BACT/5-74               ek---KIWPEYFQ..AITDGKKTFELRL.NDFDIEDGDTLLLREWDPK.........SKE........YTGRELEREVGYVGK--........--.-.-.......---------wkiddltqfw...........
M9SC14_9EURY/4-81                   ..HDLKILPQFFQ..AVVDGRKTFELRReDDRMFHIGDTLTLCEWRP-.........GSG........HTGRQCKVAVVYILRHAd......fAD.G.I.......PEGYAVLSI.....................
A0A0G0MDG0_9BACT/4-83               ek---KVLSQYFE..KILDGSKKYELRL.ADWKCEIGDILILREIDE-.........SRN........YTGRILEKEVTYVLKTK........--.-.-.......---------dinlftpeevekygyqvig..
W8FAL7_9BACT/20-95                  ..HELKVWPACFA..AVETGAKPFDVRE.NDRHFSVGDVLLMREYEPE.........SEQ........YSGRTTTRWISYILNGG........AF.G.V.......AAGWCILGF.....................
A0A0G0UQA7_9BACT/4-74               kk---KTWTEGFE..KILSGEKTFDARL.VNFECKPGDTLVLEEYDPA.........RRK........YTGRKIEKEISFVLDTK........K-.-.-.......---------qkywsqsd.............
A0A0G1DEZ4_9BACT/4-74               ek---KVWPEYFR..KIKSGEKTFELRL.ADWKCKIGDVLVLKEWDPK.........TQK........YTGREISKKVTYVIKTK........--.-.-.......---------nqkfwskee............
K8E4A8_CARML/4-76                   ..HELKIASEFFE..AVKDGRKKFEIRK.NDRDYKVGDILILLEYDKY.........YEA........FTGEKITVEIIYMTD--........-Y.A.Q.......QDGYVVLGI.....................
A0A0G0QDD6_9BACT/5-74               .k---KTWPEAFG..KILSGEKTFDARL.ANFDCKVGDILVLEEYDPN.........IKK........YTGRKIEKKITFALNTN........--.-.-.......---------kqkywsqsd............
A0A0G0XJX9_9BACT/1-71               .m-----------..--LSGEKTFDARL.ANFNCQIGDILVLEEYDPE.........LKK........YTGRKIEKKITFILNTK........N-.-.-.......---------qkfwtqsdinkqglvimaf..
A0A0G1U561_9BACT/5-75               kk---KTWPEYFE..KVLSGEKQLEFRV.ADFAIASGDELILEEWDSE.........TKE........YTGRSVSKKVGYVGT--........--.-.-.......---------ftldsfgqrea..........
A0A0G1PNJ1_9BACT/5-71               hk---KVWPVYFE..SLLSGKKTFELRL.NDFEIEEGDTLVLEEWDPQ.........TKT........YTGRTLEKVVTYVGK--........--.-.-.......---------friddlf..............
B2TNZ8_CLOBB/5-89                   ..HELKILPQYFS..DVVSGKKIFELRK.NDREFEVGDTLVLKEYLQEisdrykttlHAQ........YTGQEVKKEISYILDGG........KY.G.L.......QEGYVILAL.....................
B0T870_CAUSK/4-79                   ..HELKTWPQYFA..AVRSGKKRFEIRR.NDREFAVGDVLVLREFDPE.........QDV........YTGQVEERQITFLLSEE........DY.G.V.......IHGFVAIGF.....................
D4MVL8_ANAHA/411-483                ..HRLKLAKMFFD..AVDTGNKSFELQK.NDRNYQIGDVLELHEMS--.........DGE........ETGRVTEKQVIYIME-G........FK.G.L.......EEGYCILGL.....................
A0A0G0M7Q3_9BACT/4-84               ek---KVWPEYFQ..KILDGKKKYELRL.ADWECSEGDLLLLKEWNPE.........TKE........YTGREIEKTITYILKTN........--.-.-.......---------dinfwpkedvekygyqiis..
R6T3D1_9FIRM/130-204                ..HTLKLEECFCE..AVVTGKKCFEIRK.NDRGFQPGDTIEFIPVSNG........hPAI........HVISNRRYRITYVLS--........GW.G.L.......KNGYVAFGI.....................
A0A0D8Q9M7_9GAMM/12-90              ..HVVKTKYEFFN..AVISGDKRFEIRK.DDRDYRVGDFLSQNELSC-.........DGL........ITGRSVVHQIIYKLEATae....tnSY.G.L.......LSGFCILGL.....................
A0A0G1XWZ5_9BACT/6-74               .k---KVWQEYFE..KIISGKKKLELRL.ANFEVNEGDTLVLEEWDKD.........KEE........YTGRKIEVVATYILKTK........--.-.-.......---------gqtfwpqe.............
A0A0G0IIS8_9BACT/5-75               hk---KVWREYFE..QIVSGKKKFELRL.ADFEVNEGDVLVLEEWDKD.........TKE........CVGRKIEVVATYIIKTK........--.-.-.......---------gqtfwsaee............
W8TVL4_YEREN/55-128                 ..HQLKILPEYFQ..AVIEGRKKAELRT.NDRNFKVGDYLLLAEWDGG.........TDE........YSGRKIVVEISDITQ--........CD.F.A.......APKLVMLS-f....................
A0A0G0P9Y0_9BACT/11-78              ek---KAWPELFK..LVKSGEKTFDLRL.DDFKCKPGDILVLREWDPK.........RKG........YTGRTLEKKVTFVFKS-........--.-.-.......---------keilkfw..............
K1XQT2_9BACT/5-72                   kk---KILPEYFD..AVVSGKKKFELRL.NDFDVNEGDTLVLEEWSPE.........TIS........YTGRSIEKKVTYVMK--........--.-.-.......---------fkinelfw.............
A0A0G0N686_9BACT/5-87               ek---KTWPELFE..KVKNHQKNFDVRL.ADFKCQPGDVLVLKEWDPK.........VES........YTGRVIKRKVKFVINTK........--.E.-.......---------lekfwkkseikkngfqvmgf.
J2H1A2_9CAUL/6-84                   ..HRLKPSPTYFR..AIQSGEKTFEVRR.DDRGFQKGDLLHLVEYDPAi......iaALA........LTGRSITKRISYVLTGG........QL.G.I.......ESGYVVLGL.....................
K4Z9V6_PAEAL/3-77                   ..HDLKILPEYFS..EVVEGNKKFEVRK.NDRGYRTGDVLVLREWDSL.........KEE........YTGEVFWCKVTYILK-D........SP.Y.L.......QDGFVVLGI.....................
K1ZBP3_9BACT/5-85                   .k---KTWPELFE..KLLSGEKTFDCRI.ADFEVHPGDVIVFKEYDPE.........KKS........YTGRTLRKTITFVGKTK........EW.K.FfkpedieKFGYVIMSL.....................
A0A0G1M1D1_9BACT/6-87               .k---KVQQKYFE..AVVDGRKQFEVRL.ADFKCKPGDTFVLQEQKPG.........TRE........FTGREVSCEILFKLNTK........--.-.-.......---------evenfhtkeqldkyglvvlai
R5Y974_9FIRM/3-77                   ..HALKTKPEYFG..SVRNGEKTFEVRK.KDRPFEIGDYAALNEIDES.........GTY........YTGRALLMRITYVLA-D........EE.F.C.......KPGYVVLGL.....................
A0A0G1UX10_9BACT/4-75               kk---KIWPEYFE..AVSSGKKKFELRL.NDFDVSEADTLVLEEWDPQ.........TKE........YTGRVVEKKVSYVGKW-........--.-.-.......---------kiedlaefwpi..........
A0A0G1WL94_9BACT/6-77               hk---KIWPEFFE..KVLSGEKRFELRV.ADLEISTGDTLVLEEWNPK.........TKM........YTGRSLTKTADYILKSS........--.-.-.......---------ldqfgqhdli...........
R6TFC5_9FIRM/329-401                ..HELKIVASDYE..DVISGKKSFELRK.NDRGYKQGDSLKMLEFK--.........DGK........HTGRTIDADIIYMLE-D........YT.G.L.......TEGYCILGI.....................
G5KEM2_9STRE/9-82                   ..HMLKCYPQYFE..AVKSGIKNFECRY.NDRDFKVGDELLLREYDP-.........KQG........YTDRCIVRKITYVLS-D........FT.G.L.......KDGYVILEL.....................
A0A0F4KNZ6_9LACO/4-76               ..HKLKIDSKYFD..AVRKGFKTFEIRK.NDRNFEVGDKLILQEYDRE.........KQV........CTGYELLAFVTYITN--........-F.A.Q.......KMDYVVMAI.....................
R5F6I4_9CLOT/5-77                   kk---KILPEYFR..VVRARKKNFEIRV.DEDNVQVGDLLILEEWD--.........-GF........YTGNSVRRHVKYVLRDA.......pSL.G.L.......KPGYCIIS-w....................
G5K063_9STRE/4-79                   ..HMLNCYPEYFK..AIMDGTKTFECRY.NDRDFKVGDELLLREYDPK........kGYT........YPYRCIVRKITYILS-D........FI.G.L.......KDGYVILG-v....................
H1BNZ8_9FIRM/4-75                   ..HDLKIEPKHMK..KKIIGIKPWEIRK.NDREFEVGDLLRLREWC--.........DDK........YTGVEILQTVDDVFAD-........DT.Y.L.......QPGYVMLS-.....................
A0A0G1W247_9BACT/5-73               kk---KTWPELFG..EIVAGRKTFDLRI.NDFEIADGDTLVLEEWDPK.........TKS........YTGRTIEKKVGYVFK--........--.-.-.......---------fkpeelafn............
A0A0G0S214_9BACT/1-50               .y-----------..---------ELRL.NDFEVNEGDTLILEEWDPR.........TKQ........YTGRSVKKEVTFVGR--........--.-.-.......---------fkidelfw.............
A0A0F5VF90_9GAMM/7-81               ..HELKIPSANFT..DILAGRKTHQLCL.NHRQYSVGDVLILRELDE-.........NGE........ETAQEMNSLITHVEYGN........AT.G.L.......EDGWCVLSL.....................
Q832V0_ENTFA/113-183                ..HELKILPEYFE..AVVSGDKRFEIRK.NDRNYQNGDILRLNEYQ--.........DGQ........YTGDVHVAEITYITD--........-Y.A.Q.......QDGYVVLGI.....................
A0A0G0G4U8_9BACT/6-87               ek---KAVPELFQ..KVLDGDKTFDLRL.NRFECNVGDILVLREWDPK.........KNN........YTGRVIEKEITFVLKTKeld.fwpeEE.I.E.......KHGYVVMGF.....................
A0A0G4B2Q2_9BACT/4-84               kk---KTWPDLFQ..KVFDGEKTFDMRL.ADFDCKEGDVLVLEEWDPE.........TRE........YTGRKLEKKVTFVLKTK........--.-.-.......---------gitfwtkeevgkfgyqiis..
J1GZ79_9CLOT/5-81                   ..HELKIRPEYMH..DIWDGTKTFEVRK.DDRGFLTGDYLILREYAQQg.......tFGN........YTGREVKVAVTYILR-D........SC.Y.V.......RPGYVVMGI.....................
A0A0G0L2B8_9BACT/5-87               ek---KTLPDLFE..KVKNREKNFDVRL.ADFKCSPGDVLVLKEWDPK.........LKN........YTGRVIKRKIKFVLKTKdlekfwnkKE.I.Q.......KHGFLVMG-f....................
A0A0G1NRI0_9BACT/5-72               kk---KMWPGYLE..DITSGKKKYDMRL.NDFEINEGDTLVLEEWDPA.........TQQ........YTGRNIEKKVAYVGK--........--.-.-.......---------fdlknsfw.............
F0LNE9_VIBFN/7-81                   ..HELKISTEHFI..EVLAGRKTHEVRF.NDRNYQVGDCLNLREIDE-.........SGN........YTGQEMNTQICHVLHGG........QY.G.L.......AEEWCVLSL.....................
A0A0G1TEZ2_9BACT/5-72               kk---KTWPELFG..EIVAGRKTFDLRI.NDFEIADGDTLVLEEWDPK.........TKL........YTGRTIEKKVGYVFK--........--.-.-.......---------fkpegltf.............
A0A0G1CAE4_9BACT/5-71               kk---KIWPGQFD..TVASGKEKFQLRL.ADFDIGEGDTLVLEEWNPQ.........TGQ........YTGRTMEKKVSGVLK--........--.-.-.......---------frpdelp..............
A0A0F5VH08_9GAMM/7-81               ..HEVKIQSVHFT..EILAGRKTHEVRL.NDRNYQVGDCLNLKEIDD-.........NGD........YTGQEMNSQITHVLEGG........QY.G.L.......AEGWCVLSL.....................
J9RHJ8_9ACTN/3-74                   ..HELKINERWYY..HVRDLTKNVEIRV.HDRDYQAGDTLLMTVPE--.........---........KGWLRVERRITHVLPAG.......lAD.G.I.......GHGYVALSL.....................
A0A0F9ZIZ5_9BACT/5-85               ek---KTWPELFN..KILSGEKTFDVRI.ADFKIKVKDVLVLREYDPV.........KKS........YTGRKIEKKITFVLNSK........--.-.-.......---------dqkfwpkkdinkfglaimg..
A0A0G1D3N9_9BACT/6-73               .k---KIWPGYLE..LIESGRKKYDFRL.DDFEIKEGDTIIFEEWDPK.........TKK........YTGRKVQKKAGYIGK--........--.-.-.......---------lkigdsfws............
A0A0C5WXL1_NOCSI/4-98               ..HELKTWPAMFE..AVWRGDKTFEVRL.DDRGYQRGDHVVLREWDRNllcdcasgdH-Aad...cpkYSGRRIEARVGHVLASTap...rgnQR.GfN.......GNGYVVFSL.....................
K6T5U5_9CLOT/3-77                   ..HKLKISSQNYK..AIKEGIKTFEVRR.NDTGFNAGDILVLREQGD-.........STG........YTQREIIKEVSYIQKGG........QC.G.L.......EEEFCILGL.....................
B2TRS1_CLOBB/5-89                   ..HELKILPQYFN..AVLDGTKIFELRK.NDRGFEVGDTLVLKEYLQEisdrykttlHAQ........YTGQEVKKEISYILDGG........KY.G.L.......QEGYMILAL.....................
A0A0F9YJ86_9BACT/4-76               kk---KIWQEYFE..LVKAGKKRFEVRL.ADFEVKEGDVLILEEWNPK.........TKE........YTGRKIEKKVDFVLSF-........--.-.-.......---------kldsfgqekeil.........
A0A0F9YIJ9_9BACT/5-77               ek---KTWPDSFN..KILSSQKTFDARL.DDFKIKNGDILVLREYDPT.........KKE........YTGRIIEKKVSFILKTK........--.-.-.......---------dqkywttkeiq..........
R5KJ01_9CLOT/4-86                   ..HHIKLKEQFCD..AVLSGEKPFEIRR.NDRCYQKGDHIRFVPIKNFsvegfsstiPFD........HPIKDKEYRITYIFS--........GW.I.I.......PRDYVVLGI.....................
Q1A0P1_9CAUD/5-76                   ..HDVKIEPRWFD..RIQQSEKFAEVRY.DDRDYQAGDRIRFWRTDR-.........--P........EYGHSIERRITHVLR-G........VD.G.L.......RDGYVVLSL.....................
J2PVF6_9CAUL/4-79                   ..HELKTWPQYFA..AVRSGKKRFEIRR.NDREFAVGDVLVLREFDPE.........LDV........YTGQVEERQITFLLSEE........DY.G.V.......IHGFVAIGF.....................
A0A0F9Z2S6_9BACT/5-76               kk---KIWKEYFE..LVSSGKKKFELRL.NDFEVKEGDTIILQEFDSI.........KKE........YTGRTLEKKVGYVLKF-........--.-.-.......---------klndfgqeeqi..........
A0A0G0GK40_9BACT/5-86               ek---KTIPELFE..KVLNGEKNFDLRI.AEFGCEVGDILVLREWDPE.........MNE........YTGRQLEKTVTFVMKTK........--.-.-.......---------dlkfwsqedidelgfmvmsf.
A6LYH9_CLOB8/3-77                   ..HELKITPNNYK..VIRDGSKTFELVK.YNRDFSVRDILVFQECED-.........SSG........YTGRKIVKEISYVSNKG........ED.G.L.......SEEFCILGL.....................
V4QTJ1_STRIN/4-79                   ..HMLKCYPEYFE..AIMDGTKTFECRY.NDRDFKVGDELLLREYDPK........kGYT........YPYRCIVRKITYILS-D........FI.G.L.......KDGYVILG-v....................
A0A0G1YXM0_9BACT/5-85               kk---KSWPASFK..AVRSQGKNFELRL.ADFKAKKGDVLLMREWNPK.........TRK........FTGKELRRKIKYVLKFG........--.-.-.......---------lndygqrkkiekkglyvlg..
A0A0G0YKY0_9BACT/5-72               ek---KTWPEFFR..KVKDGKKNVEIRL.ADFKIKKDDILVLREWNPK.........KRS........YTGWIVKRRVGAVHK--........--.-.-.......---------vnmfkfhs.............
A0A0G0C8X7_9BACT/5-86               ek---KTWPELFN..KILSGEKTFDARI.ADFNVKKGDILVLREYDPV.........DKS........YTGRKIEKKISFVLNSK........--.-.-.......---------dqkfwtkkdinkyglvimgf.
X2H0U5_9BACI/244-319                ..HELDSYPEQFE..AILQGLKTFMCGF.NNQSFRVGDKLKINEFDDD.........KIL........YTGRFVEVKVIYLQEGG........AN.D.I.......PEDYVIMSI.....................
R9TAF8_9EURY/14-88                  ..HKLKILLQDFE..QAITGIKNFEQIN.DNGDYQVNDLLVLKEWDPD.........TEG........FTGREAARRIRHVPK-N........VP.C.L.......NSEYAILDI.....................
G7Q5K8_9DELT/5-88                   ..HELKTDPAVFQ..DVYSGEKTWEIRR.DDRNFCVDDCLLLLETQHT........gQ-EmqdgkplvYTGRAVLAHVTYVFSGP........AY.G.L.......AAGWCIMSI.....................
A0A0G1WMJ8_9BACT/5-71               kk---KIWPEYFG..AVVSGKKKYELRL.NDFEVNEGDILVLEEWDPE.........TKQ........YTGRNVEKRVTYVGK--........--.-.-.......---------fkidqlf..............
A0A0C1DXY3_9FLAO/3-76               ..HDLKINYEFAQ..LHFIGKKNWELRK.NDRDFKVGDTIRFTVLE--.........WES........SSNWKYERTITNVLEDT........TL.G.L.......QEGYVILSI.....................
A0A0G1AJE3_9BACT/20-101             ek---KCQPEHFK..KILNGEKNFELRL.ADWQCQPGDILILREWDPE.........TKD........YTGRQIEKEVGYILKTK........--.-.-.......---------nitffskadaekygyqvigf.
R6E210_9FIRM/6-79                   .k---KILPIYFD..AVESRQKNFEIRK.DDDDVQVGDKLVLGEWKE-.........NYG........YTGRFATRKVKFVLRNV.......pEY.G.L.......KEGYCIIG-w....................
A0A023CIU1_GEOSE/7-79               ..HRLKIWPEYFE..AVRSGKKTFEIRK.NDRGFQVNDLLLLQEYNPK.........TQE........YTGRELLVEVTYITD--........-F.G.Q.......PKNQVVMSI.....................
#=GC seq_cons                       .....KhhPcaFc..tVhsGcKsFElRh.sDhchpsGDhLlLcEaDsp.........spp........YTGRplc+cloaVhc.t...................................................
//
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