GenomeNet

Database: Pfam
Entry: DUF3858
LinkDB: DUF3858
Original site: DUF3858 
#=GF ID   DUF3858
#=GF AC   PF12970.2
#=GF DE   Domain of Unknown Function with PDB structure (DUF3858)
#=GF AU   Ellrott K
#=GF SE   JCSG structure PDB:3KD4
#=GF GA   27.00 27.00;
#=GF TC   27.60 32.50;
#=GF NC   26.80 26.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR024544;
#=GF CC   This family is based on the third domain of the PDB structure
#=GF CC   3KD4(residues 410-525).  It is structurally similar to part of
#=GF CC   neuropilin-2 (Z=4.6, rmsd 3.6A for 83 CA, 7% seq id).  This
#=GF CC   domain and the second domain appears to be part of
#=GF CC   peptide-n-glycanase (1x3w, 2g9f).
#=GF SQ   27
#=GS B6VW57_9BACE/400-515    AC B6VW57.1
#=GS A6LB40_PARD8/410-525    AC A6LB40.1
#=GS A6LB40_PARD8/410-525    DR PDB; 3KD4 A; 410-525;
#=GS A6LB40_PARD8/410-525    DR PDB; 3KD4 B; 410-525;
#=GS D0TC52_9BACE/410-525    AC D0TC52.1
#=GS F9Z8K4_ODOSD/465-580    AC F9Z8K4.1
#=GS A9EST3_SORC5/1157-1265  AC A9EST3.1
#=GS C3RD28_9BACE/400-515    AC C3RD28.1
#=GS D1K8F2_9BACE/400-515    AC D1K8F2.1
#=GS Q64N43_BACFR/408-523    AC Q64N43.1
#=GS E1YV53_9BACE/408-523    AC E1YV53.1
#=GS B5CWL2_9BACE/431-540    AC B5CWL2.1
#=GS D7IU83_9BACE/410-525    AC D7IU83.1
#=GS E4W1M5_BACFG/408-523    AC E4W1M5.1
#=GS B7B9J1_9PORP/387-502    AC B7B9J1.1
#=GS D1JVI7_9BACE/408-523    AC D1JVI7.1
#=GS F7LV92_9BACE/408-523    AC F7LV92.1
#=GS C3Q5D1_9BACE/400-515    AC C3Q5D1.1
#=GS E1WQN3_BACF6/408-523    AC E1WQN3.1
#=GS A7AFL8_9PORP/446-561    AC A7AFL8.1
#=GS C7X896_9PORP/410-525    AC C7X896.1
#=GS A5ZIC1_9BACE/400-517    AC A5ZIC1.1
#=GS G8UKI5_TANFA/428-541    AC G8UKI5.1
#=GS Q5L7X0_BACFN/408-523    AC Q5L7X0.1
#=GS C6IB98_9BACE/408-523    AC C6IB98.1
#=GS C6IS70_9BACE/399-516    AC C6IS70.1
#=GS Q8A569_BACTN/399-516    AC Q8A569.1
#=GS H1DJ43_9PORP/479-596    AC H1DJ43.1
#=GS D7IK65_9BACE/399-516    AC D7IK65.1
B6VW57_9BACE/400-515               ...............YRLITLPRAKTGIAMNG..YGFGNTERTTNLLLPGMTDETYICIVNVPSDMQVCTPQKAKEIVNAVGKLKITVQTTEDKTEVTRSLRLNKQWITPT..DYADFHRLMSEWEDSHHTTLLL..............
A6LB40_PARD8/410-525               ...............FAICVLPAISAGIDSWG..MSALNSKRSNLFELPSLIREEVTYTVTPAEGMKLQTSTQEQVISKPFGKVTRTITPRGNTIEVVRTIELNKQQFTPA..EYSDVRSLIHEWTNPDNRVLLF..............
#=GR A6LB40_PARD8/410-525    SS    ...............EEEEE----SSGGGGTT..-TT--S---S-EE-SS-EEEEEEEEEEE-TT-EE-S--S-EEEEETTEEEEEEEEEETTEEEEEEEEEE--SEE-HH..HHHHHHHHHHHHH-GGGGEEEE..............
D0TC52_9BACE/410-525               ...............FAICALPAISAGIDSWG..MSALNSKRSNLFELPSLIKEEVTYTVTPAEGMKLQTSTKEQVISKPFGKVTRTITPKGNTIEVIRTIELNKQQFTPA..EYKDVRSLIHEWTNPDNRVLLF..............
F9Z8K4_ODOSD/465-580               ...............YYFFYLPVCYKGITGKS..YAYYNTSRSKNLYLPASVDENYSYDIQLPENLTLCTPIQEKKIDNPIGSFKITLTSEGSSLHIELALQIKKQLITPA..EYPAFRSLITEWTDRTRKPILF..............
A9EST3_SORC5/1157-1265             pavptqrlatefasl-----------------..-----STRTRDVIIPALTTRRDEWTIRIPAGWRVTRAPLPQDVDTPFGKFSLSVEQSAGKIVVRSQISLTKSRIKPS..EYMAFRTF--------------cetadrvfgqrvvf
C3RD28_9BACE/400-515               ...............YRLITLPRAKTGIAMNG..YGFGNTERTTNLLLPGMTDETYICIVNVPSDMQVCTPQKAKEIVNAVGKLKITVQTTEDKTEVIRSLRLNKQWITPT..DYADFHRLMSEWEDSHHTTLLL..............
D1K8F2_9BACE/400-515               ...............YRLITLPRAKTGIAMNG..YGFGNTERTTNLLLPGMTDETYICIVNVLSDMQVCTPQKAKEIVNAVGKLKITVQTTEDKTEVTRSLRLNKQWITPT..DYADFHRLMSEWEDSHHTTLLL..............
Q64N43_BACFR/408-523               ...............YLVFTLPVERGSLAGSQ..YVRFNSQRTSNLLLPGLADESFTYTIDTPAGMEPVTRPMEKKMDNAVGTLTISIRPEGAKTRVIRSLKLKKQMIRPA..DYAAFRQLMTEYGAVDGLTLVY..............
E1YV53_9BACE/408-523               ...............FAICTLPAITGGIDSWG..MSALNSKRSNLFELPSLIKEEVTYTVTPAEGMKLQTSTKEQVISKPFGKVTRTITPRGNTIEVVRTIELDKQQFTPA..EYSDVRSLIHEWTNPDNRVLLF..............
B5CWL2_9BACE/431-540               .tlndptpartlyay-----------------..--AANTTIPENILLPRTVNCTLETIVCLPEGMK-VTPRANKEISNACGKVVFSYQPTKEGMKVTRSLRISRQLQTPS..SYKELYALLAEWRDTHNHTLV-v.............
D7IU83_9BACE/410-525               ...............FAICVLPAISAGIDSWG..MSALNSKRSNLFELPSLIREEVTYTVTPAEGMKLQTSTQEQVISKPFGKVTRTITPRGNTIEVVRTIELNKQQFTPA..EYSDVRSLIHEWTNPDNRVLLF..............
E4W1M5_BACFG/408-523               ...............YLVFTLPAERGSLANSQ..YVRYNSKRTSNLLLPGAADETFTYLAETPEGMRLATPAMEKKIDNAVGTLIISILPEGGQTRVVRSLKLKKQMIRPA..DYAAFRQLMIEYGAVDGQTLVY..............
B7B9J1_9PORP/387-502               ...............YATISLPDAEYGFSHLP..YGYLNSKRKENLLIPRPVSEVYTYTIECPENMELRTPRMYKAISNTAGKLSIIVKKEGRTATVTRSLELSKQLYTPA..EYKDLRQLLTEWSDVNGKTLLF..............
D1JVI7_9BACE/408-523               ...............YLVFTLPVERGSLAGSQ..YVRFNSKRTSNLLLPGLADESFTYTVDTPAGMEPVTRPMEKKMDNAVGTLTISIRPEGAKTRVIRSLKLKKQMIRPA..DYAAFRQLMTEYGAVDGLTLVY..............
F7LV92_9BACE/408-523               ...............YLVFTLPVERGSLAGSQ..YVRFNSKRTSNLLLPGLADESFTYTVDTPAGMEPVTRPMEKKVDNAVGTLTISIRPEGAKTQVIRSLKLKKQMIRPA..DYAAFRQLMTEYGAVDGLTLVY..............
C3Q5D1_9BACE/400-515               ...............YRLITLPRAKTGIAMNG..YGFGNTERTTNLLLPGMTDETYICIVNVPSDMQVCTPQKAKEIVNAVGKLKITVQTTEDKTEVTRSLRLNKQWITPT..DYADFHRLMSEWEDSHHTTLLL..............
E1WQN3_BACF6/408-523               ...............YLVFTLPVERGSLADSQ..YVRFNSKRTSNLLLPGLADESFTYTVDTPAGMEPVTRPMEKKMDNAVGTLTISIRPEGAKTQVIRSLKLKKQMIRPA..DYAAFRQLMTEYGAVDGLTLVY..............
A7AFL8_9PORP/446-561               ...............YATISLPDAGYGFSHLP..YGYLNSQRKENLLIPRPVNEVYTYTIECPENMELRTPETDKTIRNAAGSLTISVKKNGRTATVTRSLELNKQLYTPA..EYKDLRQLLTEWSDVNGKTLLF..............
C7X896_9PORP/410-525               ...............FAICVLPAISAGIDSWG..MSALNSKRSNLFELPSLIREEVTYTVTPAEGMKLQTSTKEQVISKPFGKVTRTITPKGNTIEVVRTIELNKQQFTPA..EYSGVRSLIHEWTNPDNRVLLF..............
A5ZIC1_9BACE/400-517               ...............YRKFELPQARNGWAAYEgrSTVVNTTRPVNLLLRYLPDETYTCIVKVADGMRPVVLPTDKKIDNPVGTVGVTVKKAAKEIKIVRTLKLKKQLITPA..EYPAYYRLMSEWLDTGESVLLF..............
G8UKI5_TANFA/428-541               ...............YALYTLPAIDKGIDTWR..L-RLNSTRTQPMELPCRIKEACSYTLTV-DGWDVETRPFRKEISNPVGKISLTMHREDNRLIIRREIELQKSIIEPN..EYHAFRSLVLLWKNDAFRTLI-l.............
Q5L7X0_BACFN/408-523               ...............YLVFTLPVERGSLAGSQ..YVRFNSKRTSNLLLPGLADESFTYTVDTPAGMEPVTRPMEKKMDNAVGTLTISIRPEGAKTRVIRSLKLKKQMIRPA..DYAAFRQLMTEYGAVDGLTLVY..............
C6IB98_9BACE/408-523               ...............YLVFTLPVERGSLADSQ..YVRFNSKRTSNLLLPGLADESFTYTVDTPAGMESVTRPMEKKMDNAVGTLTISIRPEGAKTRVTRSLKLKKQMIRPA..DYAAFRQLMTEYGAVDGLTLVY..............
C6IS70_9BACE/399-516               ...............YRKFDLPQARGGWASYDgrVTALNTTRPVNLLLRYLPDEAYTYIVKIDAGMKPVVVPTNKKIENAVGIMEVTVKKAEDKIEIFRTLKLKKQLITPT..EYPAYYRLMAEWMDTNGNSLLF..............
Q8A569_BACTN/399-516               ...............YRKFDLPQARGGWASYDgrVTALNTTRPVNLLLRYLPDEAYTYIVKIDARIKPVVVPTNKKIENAVGIIEVTVKKAEDKIEIFRTLKLKKQLITPT..EYPAYYRLMAEWMDTNGNSLLF..............
H1DJ43_9PORP/479-596               ...............YLLYNLPVLPTGIHSWQ..LNMLNSDRKTALELPYLLEENYEYTIHLPENKDLKNKNIEIHLKNKAGSVDISLKQENKTVKIKKNLILSKRVYQPSsqEYGQLRELITSWLSNGTEDL--ii............
D7IK65_9BACE/399-516               ...............YRKFDLPQARGGWASYDgrVTALNTTRPVNLLLRYLPDEAYTYIIKIDEGMKPVVVPTNKKIENAVGIMEVTVKKAEDKIEIIRTLKLKKQLITPD..EYPAYYRLMAEWMDTNGNSLLF..............
#=GC SS_cons                       ...............EEEEE----SSGGGGTT..-TT--S---S-EE-SS-EEEEEEEEEEE-TT-EE-S--S-EEEEETTEEEEEEEEEETTEEEEEEEEEE--SEE-HH..HHHHHHHHHHHHH-GGGGEEEE..............
#=GC seq_cons                      ...............YhlhsLPstcsGlus.t..hsthNScRosNLLLPuLs-EsaTYsVssspGMc.sTsshcKcIsNslGplslolpspusphcVhRoLcLpKQhITPu..-YssaRpLhsEWtsscspoLla..............
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