GenomeNet

Database: Pfam
Entry: DUF4380
LinkDB: DUF4380
Original site: DUF4380 
#=GF ID   DUF4380
#=GF AC   PF14315.5
#=GF DE   Domain of unknown function (DUF4380)
#=GF AU   Eberhardt R
#=GF SE   Jackhmmer:Q7UYS3
#=GF GA   29.40 29.40;
#=GF TC   30.10 30.70;
#=GF NC   29.10 29.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR025488;
#=GF CC   This family of proteins is found in bacteria, archaea and
#=GF CC   eukaryotes.  Proteins in this family are typically between 288
#=GF CC   and 372 amino acids in length. There are two completely
#=GF CC   conserved residues (G and E) that may be functionally important.
#=GF SQ   30
#=GS U5Q609_9BACT/41-272       AC U5Q609.1
#=GS A0A0C1P6W8_9PSEU/13-195   AC A0A0C1P6W8.1
#=GS Q21JR3_SACD2/57-345       AC Q21JR3.1
#=GS K9D793_9BURK/32-318       AC K9D793.1
#=GS A0A0M9UF78_9BACT/36-298   AC A0A0M9UF78.1
#=GS Q5H6C8_XANOR/75-369       AC Q5H6C8.1
#=GS E6WUB2_PSEUU/31-324       AC E6WUB2.1
#=GS C5BPK4_TERTT/57-354       AC C5BPK4.1
#=GS A0A0C7NPE3_9THEO/16-314   AC A0A0C7NPE3.1
#=GS Q11P91_CYTH3/75-295       AC Q11P91.1
#=GS K9RCR4_9CYAN/49-317       AC K9RCR4.1
#=GS B3PDI4_CELJU/33-239       AC B3PDI4.1
#=GS A0A0F2QMX5_9RHOB/1-292    AC A0A0F2QMX5.1
#=GS A0A0S8JIC7_9BACT/101-306  AC A0A0S8JIC7.1
#=GS A0A0R0ALK8_9GAMM/1-293    AC A0A0R0ALK8.1
#=GS Q2RGX0_MOOTA/16-319       AC Q2RGX0.1
#=GS B3PL34_CELJU/26-320       AC B3PL34.1
#=GS Q8P3C5_XANCP/43-337       AC Q8P3C5.1
#=GS A0A0M2PXQ1_PROHO/78-330   AC A0A0M2PXQ1.1
#=GS C5BMK8_TERTT/54-250       AC C5BMK8.1
#=GS S0EU37_CHTCT/38-196       AC S0EU37.1
#=GS A0A098UFI2_9BURK/26-319   AC A0A098UFI2.1
#=GS A0QZF1_MYCS2/19-307       AC A0QZF1.1
#=GS I3IBT1_9GAMM/40-290       AC I3IBT1.1
#=GS Q21L48_SACD2/136-242      AC Q21L48.1
#=GS A0A143HNW8_9GAMM/70-358   AC A0A143HNW8.1
#=GS D9WIT1_9ACTN/25-325       AC D9WIT1.1
#=GS B8CXN3_HALOH/13-294       AC B8CXN3.1
#=GS A0A098LE53_9BACT/82-287   AC A0A098LE53.1
#=GS A6GIW0_9DELT/1-249        AC A6GIW0.1
U5Q609_9BACT/41-272                  ..............................................apqgwdgdgy------------------------------....----------.-.-.-..-....-------.---.---....--...-------.....---------------------W..P.GPPDHILdG..GVYE...CNTEN.....NLVT..LKSPVD.KRTG..LQIQRQFTV-NPDVA...TIDISATFTNKIDK.DIRWSV..W....PVCQV......A.......V......DEQAV---....-E.QS.Q-....I.V......CPAKK.DSK...........GNAQYKVLHGLannpqYMCDEAGNl.vVAYKYIVGKVGTDSADGWIACVNrsSGKVLVMNFDVADGA.E-YPD.GT.SLQV...WtqgegatysrgrvnIH....KSDRK.........V..NPP.YMEMEILSPLVKLSPGESYD.--------fqyti.....................................
A0A0C1P6W8_9PSEU/13-195              .....................................................dvl----WMDNGLVRLGLAPALGGRLLSLRASGpggyGPELLWRNDA.L.LtD..E....LAPRDGH.QPRpHSG....AL...GDWVNYG.....GEKTWPAPQGWDGPGQW---AG..P.PDPVLDS.G..RYTA...TVEDPgaggcGAVT..MTSGDD.PRTG..LRLTRRYEL-DRSAA...SYRLQLTATNTADS.TVRWSL..W....NVTQL......A.......-......--------....--.--.--....-.-......-----.---...........-----------.....--------...-----------------------..---------------.-----.--.----...-..............--....-----.........-..---.--------------------.--------gggsggtfvagpaev...........................
Q21JR3_SACD2/57-345                  ........................................................IQQLQLSNQISTFTITPQIGGRGLHFGLVG....ADNVLKVNER.L.L.S..L....PAPKVSS.SSD.NIG....YL...GHINWIG.....PQAEWWLHQTENLERRQQKAVW..P.PDAHTVL.A..SATL...NAISG.....NAVT..MTLPAS.PVTG..LRLDKSYGL--HDDG...SLQLDVTATNTRQA.SVAWDI..W....FNTRL......N.......A......NSVLYVPV....AG.AQ.NV....R.I......DTFGE.TPF...........-KQSVVVDEGM.....LTIDL---...TVADRLKGKAFVQPSKGWMAAFT..ADQLFVIEFTLQPQA.VIHPA.QG.QLEF...Y..............LD....YSAKS.........V..DAG.LLEMELHSPYTHLEPGESFS.AQEVWRVY..........................................
K9D793_9BURK/32-318                  .....................................................psh----RLDNGVVQARIAEPAGGRLLSFALAG....KPNFLLVDET.A.G.-..A....PDAIPNA.ASG.HVP....YQ...GHEVWIG.....PQSEWWVHQDVNPARAAAQAAW..P.PDPWLSL.A..TYTL...VEHKR.....DEIV..LDSPAS.PVSG..IQLRKRYALVADKPH...SLRLEAEATNRSGK.QAGRDI..W....FNTRV......P.......A......HTMAYVPV....AA.PD.DV....R.I......EPA--.---...........GALRYTLAGGL.....LSLDL-PA...PGDPARKGKLFVQPSSGWLAAFR..DGQLLVIQFAHQPRA.AIHPA.QG.QVEL...Y..............QD....IDPRA.........A..DKG.MLELEVHAPYVRLAPGEAMR.ASELWTIL..........................................
A0A0M9UF78_9BACT/36-298              ......................................................vy----QFSNNTVSLEVAPLVGGRILQYKL-G....THGFFFVNAE.Q.L.G..K....PVPS--A.TLG.QVG....AW...GNQ---G.....GAKLWPA-----PQGWDGATQWpgP.PDPVLDG.G..AYTV...LEKAN.....RSIT..LQSPDDkEYTG..IRFTHKISL-DAIGS...GVVFDVTMKNISDR.QIRWGI..W....SHVQL......D.......A......SL---SGS....ND.FN.HL....R.LfcplnpNSHFE.KGY...........DVIFGEKENPS.....YRINADSSkfeAEYLYQVGKVGIDSPGDWVATLNpeTGDVFVQKYAFVSGA.D-YPE.GS.SVEV...W..............T-....-----.........-..---.--------------------.--------ngvgsyhayg................................
Q5H6C8_XANOR/75-369                  .......................................................v-ECIQLRSKAVELSATPAFGGRVLSFNLRG....QPNVLKVGAA.V.E.Q..Q....PAPEVSA.ASG.DIA....YF...GHDVWVG.....PQSQWWLHQQLNHERQAAAAVW..P.PDPYLSL.A..HTHL...ARRSH.....DALE..FEGVPS.PLTG..VQLRKQIQLSAGRAD...TVEIQASARNIRTE.AIAWDL..W....FNTRV......A.......A......TTRVFVPV....AA.AG.DI....R.V......QPPSE.AGT...........TAPRFKRARGV.....FALRADAG...QDGLIQRGKLLLQPSAGWMAGFA..GGQVLLIRFAHQPLA.AIHPE.QG.QVEL...Y..............LD....TPRRH.........P..EQG.LLEMEVHAPYRQLAPGAQMQ.AQEQWTLL..........................................
E6WUB2_PSEUU/31-324                  .......................................................q-ARVRLESPQLQLEVSPRLGGRMLHISLPG....APNLLRVGEA.V.D.S..Q....PDPKVSA.NAD.NIP....YM...GHEVWTG.....PQSQWWTGQTLNQARRKAAAVW..P.PDPWLSH.G..KTRV...LEQGD.....TRLV..LEGAAS.PVSG..VQLVQGFDL---SHE...RAELAVEMRNIRKE.PVSRDI..W....FNSRV......P.......P......DTRVYVPV...aAD.GS.GV....R.V......RSDTE.DGY...........DALVTSSDDGL.....FSLELLPP..gEGLQGRRGKVFIQPEAGWIAGFN..AGQAFVIHFEKQPVE.RIHPE.QG.QVEL...Y..............LD....WRPDP.........A..YPS.LMELEVHAPFVTLEPGQSTT.AREWWIV-r.........................................
C5BPK4_TERTT/57-354                  ........................................................VQQITLGNGVVSLQVTPDIGGRVLGVSLTD....RQNLLRVGTE.E.L.A..R....GVPEVKA.DDR.AYS....YF...GHIVWNG.....PQSDWWKFQTVNPQRRAQKAQW..P.PDPFNVL.A..RNEI...VAHTA.....ESLV..LQSPPS.ALTG..LAMRKVFRLPAKHKN...SVELMVDAQNAQPEgSVAWDL..W....FNTRV......S.......A......ASKVLVPV....AS.EQ.QV....R.V......QQPFY.PKQ..........qDPIAYTVAEGT.....LVLNQLAA..tAPSRKRVGKLFITPDAPWMASFS..QGQVLLIQYPSVPSA.DIHPE.HS.LVEL...Y..............MD....FDGDD.........F..AAG.LIEMEVHSAYRELAPGTTLT.SRERWTVL..........................................
A0A0C7NPE3_9THEO/16-314              ......................................................ga---VEFGNDLIRVVMVPALGGRIMAYDLGD....-YSFLYVNKE.L.E.G..K...lFTPEENY.GDG.SIAawknYG...GDKTWPA.....PQG--W-----DTE---EEWHG..P.PDPLLDT.GvyTGRW...LECSP.....EKVSyeVESPPD.TRTG..IKIFRKVTI-RQDSS...KLWLELRMKNVSSR.PVAWSI..WnvtqLDTRL......R.......SsngydtNCHLYIPL....NP.ES.RFakgyR.V......I--FG.EED...........NPQWGRREGDL.....LVVP----...--YLFYVGKIGVDSPAGWMAFVNgtEGYTWCLRYPYYPGEkEAYPD.GGcTVEC...W..............--....-----.........-..---.--------------------.--------tvgrgvvagkdysqetgyhleaevlgpirklkpeeiq.....
Q11P91_CYTH3/75-295                  .............................sgtnilsgktvnagnwgtsmwpspqra------------------------------....----------.-.-.-..-....-------.---.---....--...-------.....-------------------WGW..P.PSQQLDN.L..AYT-...VLQDS.....GAVV..LKSQKD.PKQG..FVFTKAYSI---DTK...DTSLIITYTILNDT.TVAQKVagW....EISRV......A.......P......GGLTFYPS....GD.EA.K-....-.-......-----.RGQ...........LAPLTKDTLGV.....TWFEYKAA...-TIPSGVPKLLADGKEGWLAQAK..GALLLVKTFEDVATG.KYAPE.EG.EIEL...Y..............A-....----N.........P..DHS.YIEIEQQGTYVQLKAGETLT.Y-------vvryklv...................................
K9RCR4_9CYAN/49-317                  ....................................................dsyi-----LSNSQVEAVIVPAI-GRIMQFRFPD....GENTFWEDSQ.L.Y.G..K....-VPNKKS.EEW.N-N....FG...GDKTWPA.....PQSEWK---------KMTKISW..PpPDTFDSV.P..VK--...VEVQK.....NEIT..LISEID.PFYG..IRFYRQITL-EPNEP...IMKVTTTFEKVKGD.SQQVSV..W....TITQL......N.......E......PVSVFAAI....PQ.PS.IF....P.Q......GYNKQ.SDD...........LPANLKIDNGI.....LSLTRDRD...--KPHKIG-----SDASTLLWVG..EKTAVRMDSPR-IDK.VIYPDnNS.NSEI...Y..............TN....YDPKA.........-..---.YVELEFLSPLKTLQVGEKMD.LTVT----ytli......................................
B3PDI4_CELJU/33-239                  ...............................................sgtvlwssp------------------------------....----------.-.-.-..-....-------.---.---....--...-------.....----------------QAEWNW..P.PIDVLDS.L..P-YK...VETQN.....NQLV..LTSEVD.PKTG..YQFSKTYLP--AGKN...AIAVTYRIYNRGKV.EKRVGA..L....EVTRV......P.......P......AGDVLFPL....GD.TA.PV....-.-......SGI--.--F...........YPLPVSLEQGL.....CWFQYDGK...-KIRDDHHKIMLDGKEGWVAYRN..KGYLLIKEFEDLPPN.VIAEG.ER.EIEV...F..............--....---AH.........V..EHT.FIEIKQQSAVETLAPGEFLT.WTVVWH--al........................................
A0A0F2QMX5_9RHOB/1-292               ......................................................me--YITLERSGVAVTITPAFGGRVTGFGLAG....RDSMVLFDAT.LaA.E..Q....PAPPVEI.SAA.ALP....YQ...GQSLWVG.....PQSEWWTHQTAAPE--MQGESW..P.PDPYLTT.V..KTRV...IR-TP.....YSVT..LQGPAS.PYTG..LKVHQTYEL--LESG...CLKLTAVAENTRQT.PVSWDL..W....TNVRV......P.......G......DAWVFAPV....SD.AA.AI....R.P......GPTND.PAF...........QPPQLGYADGL.....AFADPSMD..gVTAPAREGKVFLDTDEGWMAGVR..DGQAFRVSFALSPLA.AIHPA.QG.QVEF...Y..............FN....QPSDK.........S..SAG.VIEMETHAPYRTLQPGETMQ.AVQFWSI-q.........................................
A0A0S8JIC7_9BACT/101-306             ................................................npprhlpl------------------------------....----------.-.-.-..-....-------.---.---....--...-------.....----------------------..-.-----WL.G..RYRA...EKIDA.....VTVR..VTSPQD.EATG..ILLVKEIKL-APAGA...GVSIRQTMKNVGQG.DTAYCL..W....DRTLT......P.......A......GGYGFFEL....NP.KS.RF....R.A......RWSMR.RGErrawrydgvepSSPRVRIVGGL.....LVTI--PG...EQM----EKVGGDCERGWVAGSR..DSWLFVKRFPVQPAG.DYADG.GN.RVEI...Y..............VD....GR---.........-..---.VTELEPLSPKVRLAPGESYS.FDERWDL-r.........................................
A0A0R0ALK8_9GAMM/1-293               .......................................................m-----LDNGTVRLEATPAFGGRILSWHLVG....EPNVLKIGEAaI.R.D..Q....PRPALSA.TAG.DIP....YL...GHDVWVG.....PQSQWWLHQDVNPARRDAAANW..P.PDPYLSL.A..NVRV...RSRDA.....RQFT..VEGIDS.PVTG..VRLRKQVRLDEESPD...TVWVEAQARNVRAT.PVSWDL..W....FNTRV......A.......A......DTRVFVPV....AD.AErDI....D.L......QASTD.PGT...........TAPRHAWNAGL.....FVLTAQSA...DSPLIQRGKYRLQPSSGWMAGFA..GHQMLLIRFEHQPRE.RIHPE.QG.QVEL...Y..............LD....APSYA.........R..GQG.LMEMEVHAPYRQLAPGERMH.AAERWTLL..........................................
Q2RGX0_MOOTA/16-319                  ......................................................ga---VEFGNDLIRVVMVPNLGGRIMAYDLGD....-YSFLYVNKE.L.E.G..K...lFTPEENY.GDG.SIAawknYG...GDKTWPA.....PQG--W-----DTE---EEWHG..P.PDPVLDS.GvyTGRW...LECSP.....EKVSyeVESPPD.PRTG..IKLFRKVTI-RQDSS...KLWLELRMKNISSR.PVAWSI..WnvtqLDTRLrngkgyD.......P......NCRLYIPLnpvsRF.AK.GY....R.V......IFGEE.DNP...........-QWGQREGNDL.....LVIPY---...---LFYVGKIGVDSPVGWMAFVNdtEGYTWCLRYPYYPEEkDAYPD.GGcSVEC...W..............TVgrgvVTGKD.........YsqETGyHIEAEVLGPVRKLKPGEE--.--------qflel.....................................
B3PL34_CELJU/26-320                  ........................................................IQRLPLNTSAISVEVTPDIGGRILAIALPG....KENFLRQGEA.V.I.S..E....PEPYVAP.DAD.NVG....YL...AQETWLG.....PQSQWWTQQLVNPARAQAKAVW..P.PDPYLIL.A..KNQV...VQADK.....RRVV..MRTPAS.PVSG..VVVEKHYALVEGKPD...QLHLMARATNIRDT.TVAWDI..W....FNTRV......P.......P......SSQVYVPV....AS.QE.DV....R.V......EHMEN.EQR...........GSLGYRLVDGF.....FTFVSKAH...PDKPGVRGKAFIQPSAGWMAAFR..EGQVFIIHFPLQPTA.VIHPE.QG.QVEL...Y..............LD....SIPEY.........P..SQG.LLEMEVHAPYRKLQPGAHME.AEQTWRLL..........................................
Q8P3C5_XANCP/43-337                  ........................................................IERLTLGNEVIEVTATPSFGGRILAFQLRG....QPSVLKLGAA.V.E.Q..Q....RAPQVSG.TAG.DIA....YL...GHDVWVG.....PQSHWWLHQQVNPQRKAAGAVW..P.PDPYLSL.A..TTRA...TIHDA.....TQLV..MDGVPS.PVTG..VQLRKRVALSPSRPD...TIDVQATARNIRTE.PLSWDL..W....FNTRV......A.......A......DTRVFVPV....AD.AA.DL....R.L......QPPSD.PGT...........VAPRYQLEGGL.....FVLSADTR...ADTLIQRGKLLLQPSAGWMAGFA..GTQVLVIRFAHQPKA.RIHPE.QG.QVEL...Y..............LD....APPQH.........P..EHG.LLEMEVHAPYRTLAPGADMQ.AQEQWTLL..........................................
A0A0M2PXQ1_PROHO/78-330              .................................................gryrlsl--------DTVTVEVDAQQGGRIIAFALDG....-ENLLRDNS-.-.-.-..-....VDPQ---.---.N--....-Y...GSTFWVS.....PQAIW---------------DW..P.PVPEIDR.A..PYQV...LQ-SD.....RSLR..LVSQPS.PSLG..IQVSKSLALGRFRADgspTLRLTYRITNTHTH.PLRYAP..W....EVSRV......S.......P......TGVTFYPT....GS.AL.--....-.-......--YGS.GSF...........GTPLTETSAGV.....TWWNHDSA...PLSQ--DQKLFAEGFGGWLAHLD..GDKLFLKTFPDITAA.DQAPR.ES.EIEV...Y..............AN....-----.........G..NHT.YVEMEAQGAYTRLAPGESLE.WTVGWSV-h.........................................
C5BMK8_TERTT/54-250                  ..................................................spqslw------------------------------....----------.-.-.-..-....-------.---.---....--...-------.....--------------------QW..P.PPVELDE.A..PYEL...VEHSP.....ERIC..LRSPVE.SQLG..IQVTKVFSP---IAN...GFNVAYVIANVLGD.IVSMAP..W....EISRV......S.......G......GLSFY---....--.--.--....R.A......ATPPE.AHS...........-TCDAVFAEGC.....YWYEY--K...VDGLTGIPKLFANNSAGWLAYVE..GNQLLVKTFPTITPE.EVAPG.EG.EVEI...Y..............GH....ADV--.........-..NNP.YVEIEQQGPFRAIMPGMRLI.WAVDWRI-f.........................................
S0EU37_CHTCT/38-196                  .....................................................nay----QLSNGDVELVVVPQIG-RIMRYGPVG....GPNMLWNNPT.M.L.G..K....TAS-LEA.AAK.EWP....NF..gGDKLWPA.....PQSVW---------------NW..P.PDPYLDS.A..PQTV...RVLPN.....HHLL..VIGQAS.PQSG..IRFEREIAL-APKGD...EVTLVNIMINTSSK.PVKWAI..W....EIFQA......N.......D......PLRVYLPT....--.--.--....-.-......-----.---...........-----------.....--------...-----------------------..---------------.-----.--.----...-..............--....-----.........-..---.--------------------.--------nisghf....................................
A0A098UFI2_9BURK/26-319              ....................................................ipvh----TLDTGSVRATVTDAIGGRLLSFALAG....QPNFLKADLA.-.A.G..D....PHAAIKP.TTE.NVG....WL...GHEIWVG.....PQKEWWSHQDVNPARA--GLPW..P.PDPWLSL.A..RYKV...EDKRP.....DAVT..LASPAS.PVNG..LQLVKRYSLVPGKPH...SLRLDVDAANTRKT.QVAWDI..W....FNTRT......H.......G......DTRVYVPV....AR.RE.DV....R.Q......QAIEPkPDM...........VPLTWTLADGL.....FSLDAYPA..gKGQPHRNGKMLLQPSSGWMAGFH..KGQVLVIQFAHQPRT.AIHPD.QG.QIEL...Y..............ND....WQPEA.........P..EQG.LMEMEVHAPYVTLAPGRHMQ.ASEQWTLL..........................................
A0QZF1_MYCS2/19-307                  .....................................................wir-------TGSLTLGVVPALGGRLLSLRLGE....RELLWRNPAL.L.G.E..D....LQPVGGHiPAP.VSG....RL...GDWCNYG.....GDKTWPAPQGWSSPQ---QWAG..P.PDPVLDS.G..HYAVdvcRWEAT.....TELA..VTSPPD.PRTG..LQITRTFTV--NTDS...EFVIHLSATNVTDH.EVTWAL..W....NVTQL......P.......G......GGTVEVDV....EH.RF.TE....P.I......EILAG.TGV...........-PTWRRSGPDT.....ITID----...--PQDVVGKLGFPYATGRLRYLH..QNVTLAWDFPVDEDA.PYPDE.GS.RAEL...W..............ME....H----.........-..---.--------------------.--------pqpaplasldgldppdrivecevlsashtlapgssmtfpvkl
I3IBT1_9GAMM/40-290                  ...........................................srllikqgkvrle------------------------------....----------.-.-.-..-....IMPKVGG.RIS.SLK....YA...GHELLVPivdldKVTDW---GTVLWSSPQTDWGW..P.PIDVLDN.K..PYRL...T-TEE.....DRVV..LMSEID.PRTG..YQFTKTYRP--SGVD...RITIDYRIANHSTE.RKNVAP..L....EVTRL......P.......S......SGSLFFPS....GD.SE.--....-.-......--ISS.GLF...........YPLDVQMIDEL.....TWFDYD-K...KKIRTDHHKMMQDGKEGWMAYVD..QGYLLVKEFNDSPAG.TTAKG.ES.EIEI...F..............--....---AH.........V..EHI.FIEMKQQASLVTLEPGQHLD.WTVTWHV-k.........................................
Q21L48_SACD2/136-242                 ..................................lpnsnlpmqregnvflyehnpk------------------------------....----------.-.-.-..-....-------.---.---....--...-------.....----------------------..-.-------.-..----...-----.....----..------.----..---------------...--------------.------..-....-----......-.......-......--------....--.--.--....-.-......-----.---...........-----------.....--------...--LLTEGVKCFANNSGGWIANIF..AGQIFIKGFPKLDEA.DVSPS.EG.EVEV...Y..............A-....--FDS.........E..SNP.YVEVEVQGPYTTIASGAQTSwAVDWWL--ip........................................
A0A143HNW8_9GAMM/70-358              .....................................................eiy----KLQNSKLSYSFTPQIGGRGLAFSAAG....EKNLLKVGTA.V.Q.E..Q....PNPDISP.QAG.FIP....YQ...GHIIWPG.....PQADWWKQQEVNPQRRAAGAVW..P.PDPFTVL.N..DYEL...TAVSD.....KSAT..IVSPVS.PVTG..LQLTKEFTL---KDD...VLLHRVTAVNRRET.PVKWDI..W....FNTRV......S.......P......ETRVYVPI....ADfSR.DL....R.L......EKFPE.MTTe.........vKADAEKQRLGL.....FGFAR---...--GENIKAKAFIEPSAGWIAAFT..QGQLFVIEFPRQARD.SIHPD.QG.QVEL...Y..............LE....QDPQN.........P..DAG.VLELEVHAPYRELAPGESMS.ATETWRA-l.........................................
D9WIT1_9ACTN/25-325                  .....................................................yel---VRLDAGAVQLTAVPALGGRLLSLTLHG....REFLYRNARL.L.D.GglR....PRPGVRP.VPQ.DGP....MS...AWLNWGG.....DK-TWPAPQGWDG-----PGQWsgP.PDSVLDS.G..PYELrltVQGGT.....AQAV..MTSGVE.PRTG..LRIERRVTLTA-GRT...AFTLENTLTNESDR.PRRWAV..W....NVTQL......AgtapgsyP......AGGVYVGT....AD.SG.--....R.P......ETVGL.IAG...........TGRPHVHRTGI.....GTLHV---...-PHQDVVGKVGFPDAAGWLAHVA..PQGTLTQRFEVSPTA.RYPDA.DS.RVEV...W..............LE....HPLHApldhlgglrP..RDR.IVECEALGPLQELAPGQST-.--------rltme.....................................
B8CXN3_HALOH/13-294                  .....................................................qgy----ELKNKVISLILLPEVGGKIVSFSYRG....QDLFFNLPEN.S.T.S..KidlsRIGDVKS.YRK.KFD....YVptgGYKTWLA.....PQSKW---------------DW..P.PYLDLEL.G..SYNMsvfQEKDK.....IQVE..LTSPVC.RESG..MRLMRVITLKAGSP-...EVTIKQGMENCSTT.DRTFGL..W....DVTQI......H.......G......EGRVIFPI....LS.DD.SL....GyI......VTPEK.NNY...........-TERYNFDGKS.....FI-SVHCP...GQEIF---KLGTGYSKGWILTLV..EKEDWLLGYLK----.-IFPV.FS.GARFghgY..............AM....EVFDT.........N..KYN.YFEVEVHGPLNKIRPQDKYF.FTEEWRVL..........................................
A0A098LE53_9BACT/82-287              ...............................................wtspqdpwg------------------------------....----------.-.-.-..-....-------.---.---....--...-------.....---------------------W..P.PIPEH-H.D..KPYK...VTATK.....NSVE..FTSEKD.AKLG..VVIKKNITA-NPSDS...SFVVSYTITNESGK.ELKVAP..W....ENTRT......K.......K......SSITFYPR....GE.KE.F-....-.-......-EQSS.PVM...........SVLKMNDIDGI.....RWFAYSPD...RVTDGNMAKLYADGSEGWIANTD..EGLLLVKKFQDTKAS.ERAPG.EG.EIEI...F..............AD....TQ---.........-..-NP.FIEMEQQGAYKTLAPGAKLT.WQVKWYL-r.........................................
A6GIW0_9DELT/1-249                   mtrpslrsesltleldpacggriaslrhgarellvspsvhpdnwgatlwtspqsdw------------------------------....----------.-.-.-..-....-------.---.---....--...-------.....--------------------GW..P.PVAAVDS.E..PYEL...VEHGP.....SAIT..LRSPVA.TMGPrrLQITKRAAV--VAGG...SIDLRYAITNLGDA.PFAMAC..W....EVSRV......F.......P......GGLSFFPT....GR.AA.--....-.-......-LTEL.PPH...........GPLEPDTEAGF.....SWFDHAA-...-FAPGQNRKLHADGEGGLLAHCV..DDLLLLKCFTDTPPA.DQAPG.EG.EVEL...F..............AF....E----.........-..DGS.YVELEVQGAYASIEPGAEL-.--------afgvr.....................................
#=GC seq_cons                        .......................................................h.....htst.lph.hsPthGGRlhthth.s....t.thhh.stt.....t..p......P..t..t.t.phs....hh...Gp.hW.u.....spt.W.............thsW..P.PDPhLsh.u..shpl...hppss.....ppls..lpSsss.PhoG..lplp+phsL...pss...slplphshpNhpsp.slsasl..W.....sTRl......s.......s......ssplahPl....us.tt.th....t........t..tp.ssh............s.thphtsGl.....hhhsh..t.....h.t.huKlhhpsssGWhAths..puplhlhpFsp.stu.shtPs.pu.plEl...Y..............hp.......tt............pts.hlEhEhpuPhtpLtPGpphp.ht..W.............................................
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