GenomeNet

Database: Pfam
Entry: DUF4401
LinkDB: DUF4401
Original site: DUF4401 
#=GF ID   DUF4401
#=GF AC   PF14351.3
#=GF DE   Domain of unknown function (DUF4401)
#=GF AU   Eberhardt R
#=GF SE   Jackhmmer:B2KEA1
#=GF GA   29.00 29.00;
#=GF TC   29.60 29.60;
#=GF NC   28.70 28.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR025513;
#=GF CC   This family of proteins is found in bacteria. Proteins in this
#=GF CC   family are typically between 357 and 735 amino acids in length.
#=GF CC   The family is found in association with Pfam:PF09925.  There is
#=GF CC   a single completely conserved residue K that may be functionally
#=GF CC   important.
#=GF SQ   52
#=GS D6YQ34_PANVC/395-724      AC D6YQ34.1
#=GS H2IY93_RAHAC/394-723      AC H2IY93.1
#=GS Q8RHL2_FUSNN/249-561      AC Q8RHL2.1
#=GS E3HN15_ACHXA/351-682      AC E3HN15.1
#=GS X4Z363_9BORD/2-127        AC X4Z363.1
#=GS A0A0C4YE92_9BURK/33-367   AC A0A0C4YE92.1
#=GS A0A060BDR1_9GAMM/31-344   AC A0A060BDR1.1
#=GS Q2SNL7_HAHCH/43-357       AC Q2SNL7.1
#=GS A5WBD7_PSYWF/434-766      AC A5WBD7.1
#=GS Q2KTM1_BORA1/341-670      AC Q2KTM1.1
#=GS A9B1L5_HERA2/33-347       AC A9B1L5.1
#=GS N8S612_ACIGI/299-601      AC N8S612.1
#=GS V4LGW7_9GAMM/55-330       AC V4LGW7.1
#=GS H1ZAR5_MYROD/37-363       AC H1ZAR5.1
#=GS E3E917_PAEPS/496-569      AC E3E917.1
#=GS B1XZD6_LEPCP/32-362       AC B1XZD6.1
#=GS U1YCQ8_9BURK/322-639      AC U1YCQ8.1
#=GS B2KEA1_ELUMP/31-348       AC B2KEA1.1
#=GS A1S5M6_SHEAM/29-345       AC A1S5M6.1
#=GS Q0K6G7_CUPNH/32-365       AC Q0K6G7.1
#=GS Q1D0K8_MYXXD/43-356       AC Q1D0K8.1
#=GS A0KLV5_AERHH/27-329       AC A0KLV5.1
#=GS A0A0B5RX03_9FLAO/36-348   AC A0A0B5RX03.1
#=GS Q1LIF8_RALME/31-368       AC Q1LIF8.1
#=GS A9HVM5_BORPD/350-681      AC A9HVM5.1
#=GS Q8A6Q3_BACTN/6-311        AC Q8A6Q3.1
#=GS C9R5Y4_AGGAD/306-664      AC C9R5Y4.1
#=GS Q7CJX4_YERPE/394-725      AC Q7CJX4.1
#=GS A0A088F1B2_9SPHI/43-355   AC A0A088F1B2.1
#=GS D6CWQ2_9BACE/6-317        AC D6CWQ2.1
#=GS I4MQV0_9BURK/198-363      AC I4MQV0.1
#=GS F2IGY4_FLUTR/42-352       AC F2IGY4.1
#=GS F9TAA5_9VIBR/28-341       AC F9TAA5.1
#=GS B5E9I7_GEOBB/30-347       AC B5E9I7.1
#=GS A0A090AEM7_9GAMM/42-352   AC A0A090AEM7.1
#=GS R6E8U4_9BACE/6-315        AC R6E8U4.1
#=GS A0A052II30_9BORD/358-689  AC A0A052II30.1
#=GS I3U7T0_ADVKW/1-287        AC I3U7T0.1
#=GS B8J1C2_DESDA/418-746      AC B8J1C2.1
#=GS H8MMH5_CORCM/43-360       AC H8MMH5.1
#=GS G2PP97_MURRD/42-352       AC G2PP97.1
#=GS F4GMT9_PUSST/325-650      AC F4GMT9.1
#=GS A8H3N1_SHEPA/44-367       AC A8H3N1.1
#=GS A0A077KNR7_9FLAO/42-352   AC A0A077KNR7.1
#=GS R5U988_9BACE/6-311        AC R5U988.1
#=GS A0LJX9_SYNFM/32-349       AC A0LJX9.1
#=GS W0P6D6_9BURK/370-706      AC W0P6D6.1
#=GS A1K370_AZOSB/32-367       AC A1K370.1
#=GS M1FL62_9ALTE/31-347       AC M1FL62.1
#=GS Q9CM56_PASMU/289-634      AC Q9CM56.1
#=GS A9BVL7_DELAS/34-368       AC A9BVL7.1
#=GS Q7VSG6_BORPE/349-680      AC Q7VSG6.1
D6YQ34_PANVC/395-724                 ................PWYLRLALSVGGWVAAIITLLLMALVLYSTDLLDdq..naVTLILPSLVLAVIARGLLR...........--SDLDGKYHLGLAWAIAA.....TCGLVFGVVL..QIQSNDVSfm.mlsSLCALPILTAMAVAMP.DRTYRF.....MAITALtff.......lvlAGYLLSLHYLSP.........................TAGRVAVSLLVGAVMFLWLWIVSHQL.....................ELLAGSYADAVHPLLYGIPTGLmll........sfpGIN------Aavl..........................mdfFWSSAQFSMLQSATGTGIAAGLVL...........................-SALSQKRSGQPLFS.IITLPAAVI...........CGAAALYAPGIGLGLWLILMARYLGSPG.LLVVSGGFLVLYVIGWYYFLEVLLLHKALLLLAGGLVLLGLAWGVTK-v.............
H2IY93_RAHAC/394-723                 ................PWYLRLTLSIGGWVAAMIILFLLILVLY--VADLlndpnaATVIIPSLLLAAVAGGLLR...........--MQGVSKHHIGLAWAIAA.....TCGLCFGFYL..LFEPGWEMsv.lvgSLCSLPVLAAMALAMR.DHAYRF.....MAITALtfl.......lilTGNLLAGLFLSP.........................IAGLGAVSTLVACVVIFWLWVIREQL.....................NLKARPVTDAVFPLLYGIPAGL..............VLLCFCGINApffyd......................lfwhpAGYFVLSSGTGTGIAAGLILGSLY...........................QVITKRTPPVPLLFV.AAIFCGTAA...........-----FYAPGIGLGMWLLLMARYQGRQG.VLAASGCILTLYIIDWYYFLGVSLLQKSLLLFATGAGLLVLAFAAQKW..............
Q8RHL2_FUSNN/249-561                 ...............k--FTNLVVGFLKILAFFLLIALVFSLLSSMGLEE......GALIVVSIILIIFSYFAAR...........--MLKFEKDKLEIVAFIAG.....LICLGGYLRF..YLEMKS--......LTVLLIVTIIYDVFWF.TMPTRA.....LDLLLLp...........lHYFLLGDFLIEK.........................LEYVDYYYIIIFVALIIEGYFI----.....................YNKKLLSNEKIKRILCGNEFTL..............LVMSTVFYYT................................-------MGAATFLIAEVIDLPSYaryynvvl...........vvftaiigLFIIFKEIKNPTLKI.VLSLMLIAL...........NYFAYSETLSLAITLLLMLVYAFRESKW.GLAVSTLATVYVIFAYYISFYKTLLDKSIALSISGGLLLVAYLVLK--y.............
E3HN15_ACHXA/351-682                 ................PWYVQCLLGLSAWLSTVLLLVFIAFS--GFITSE......GGALVAGLVLCAAGVAVLR...........-SDAGPFWRQCGTAMAFAG.....QILIIFGLSS..STSFASA-......CVFVLLMAATVYAVGP.DVILRF.....LSGLLI.............-AAAGAGLIWRG.........................LSPDLGGEDLLDAWLG---FDVMRATfvwlpiavtgawatavifsvsHRLGGKRAHALQPLAWAFLLSV..............--QGMVWLAGglsaqq...................lpamwqlNPHTAVLVVAGALLPLAAAFAVLW...........................----PRRHVLTAGVT.WGVPIALLI...........LALFWLPSPGVGFALAWLLLGFGLNQSR.LVVFGVISLLAYLGVYYYQLDVPLLQKALWLGGAALLLFVLRALVWL-v.............
X4Z363_9BORD/2-127                   ..........palwkl----------------------------------......-------------------...........-------------------.....----------..--------......----------------.------.....------.............------------.........................--------------------------.....................----------------------..............----------................................HRLTALLNIAGALLPAIVALWLLW...........................----PRRHVLTLSLV.LITPVALLL...........LALFWLPSPGIAFALTWILLGFGLNKPR.LTGFGVLSLLAYLMLYYYQMEVPLLQKAVWLTGAAVLLFLLRILVWL-v.............
A0A0C4YE92_9BURK/33-367              ................PWAVRLLMGLAGWLGAVFFLAFLLGSVFVAARDN.....aTAMALCGAAMIALAAVLYR...........RRAAATALEQFALAVSLSG.....QGLLVYGASQ..AYGGSRLLes.aafWGALALLEAVLYVLVS.NRLHRF.....LAALGVwtgva...lalhlA--------M-Tpglr.................hvwqAMSFSLGWLAPLAMTLLTGFVLAQG-.....................RLCAAGLHNWIEPAADATLLFA..............-LGAALVVTGlsqpqa...................llfeastGRHAGNYWMAGALF-GLVLAAFVL...........................--AEASRLQLSPAVR.GTALVGAAL...........FSALLAGAPAVVAAALALGLALRRSSLP.WLGLAVAALGSGFIWYYSALHWTLLIKSATLAGAGIAVLLLRMALRR-d.............
A0A060BDR1_9GAMM/31-344              ................PWFVRVLQAFSGWLAALFLLGFIATAVVFVLESS......VASLVVGSLLIGGAFALLR...........-AARSDVLEHMALAFSLAG.....QLLVAWPAVE..MWGISASL......WWVLLALQCALALIMP.SQVHRS.....MSAFLA.............SLALTMALAVNG.........................LAPVAIGLVVLVLTLLWLN-------.....................ECRWPGRIGAVQAWGAGLLVGL..............LVLQGQAYSNqlawlyd..................sgaqwfgPWLASWLSTALVALALVCVILQAF...........................-----RQHSQPAIAQrLAIYGAVAL...........VAVVSVYMPGLGAGVTVLLLGFTIGHRV.LMGSGILLLLMAASGYYYWLDVTLLMKSLMLLAMGALLLSIRWLLKRW..............
Q2SNL7_HAHCH/43-357                  ................PWFIKALVGFGAWLGSWLFIAFALGV--SLMASD......GGYIALGLLFIGGATVLSR...........-VVDHLFVNQVALATSMAG.....QLMLGFGLEE..MNLVDDVEg....iLATLILVNLALIPLFA.DRAHRF.....LSILFI.............-CVATAILLYIY.........................KQQALIPFAPPLLAAGFAWLTLNDS-.....................QSGLRRYEALTSPLAAGMIVAAlgwsllsavyvlpdLLD-------................................DFVFYPNPWISTLGIAAVLIWSLW...........................-RVLTPVFGEDKRAP.AVLIATVLI...........AAVTAHNAPGLTAACLALVVGVAQRRTF.YIGLGVVFLSVFLTAYFYGIEISLLAKSVSLVATGAVLIGVRKLLDR-i.............
A5WBD7_PSYWF/434-766                 ................PWYLQLFLILSGLLAGGLISGFIVLLLNVALKDD......IIKLTVGLLLLFVSFVLSRqelfirrdlntPLKQQAFSDSLAFALSLSG.....QAFLAVFLFE..IIDDIALS......IAAFMLMQALLLTLFT.DVLSRF.....FSSVMG.............-LLALVWLLAYA.........................QLPEASPAILALLAVLFGVHLQSVKQp...................lKGRKTFSPSLLNAMAYATSFVL..............LLISVVFIAAeyqd.......................gligiGSDFQYRYALAQLLLTLSSLYAAY...........................IILQRYQLKRISKTG.GLIALAIGL...........LAVVSVYVSGVLASSLVIIIAMANQNRT.LRGLGISALVGYIFWYYYQLDSSLLLKAGSMLAVAAALFMIRWVMRRL..............
Q2KTM1_BORA1/341-670                 ................PWLVQGLLGLSAWLATLLLLVFLFAS--GLVRSD......QGAIVLGLVLTAAGVAVLR...........-TAAGLFWRQCAIAMAFAG.....QWLVVYSFFS..NESVLNP-......NLFVVLLALAVYLLAP.DVLLRF.....LSGGLI.............-ALGMTGLILQAlqpgqgdg.........ldfwfaldT------------------MQANFLWlpvvvlgaw...aaaiafaanQGWARSRPHLLEPLAWALLVSV..............--QGLVWVASgvgvdq...................lpalwrlHRLTALLNIAGAVLPAVVAFWLLW...........................----PRRQTLTRAMV.LLTPLALLV...........LGLFWMPSPGIAFALTWLLLGFGLNKPR.LTGFGVLSLLAYLMLYYYQLQVPLLQKSFWLVGAAVLMLLLRGLVWL-l.............
A9B1L5_HERA2/33-347                  ................PWYMRIFAGIGAWFAAFMFLGFLAIT--NIITNE......FGALVVGLGLCAVAIGINR...........TNQASTFLRQLALAISITG.....QALVLFGWTI..IVESVIVA......ALGMIVLEIALFVAHR.DFSQRL.....ISTLGV.............--ITAIHVIAGDlnnw................vesfnYMYLLLSVMIISFSLLMW----FEA-.....................KIHEDQRWSSASPIAYGMLLFM..............AISSLLINFNw.............................aeFFSRGSFFILPALVGIICLGTTIW...........................MIINEFEYKLGFIEL.GCIAFGLLF...........IAFAGINTPAIIIALLIILLSYWRGYPV.MFGFGCLALIGALSLYYYNLNISLLYKSIILFGTGMMLLAIRALVLK-l.............
N8S612_ACIGI/299-601                 ..........fnnipi--------AVGAWIAGVLLAS-LMLT---FWG--......NFSLIMGAIFVVLAAFILR...........-SKQALFLRQFAYCIWVAG.....QNAVIFHTFE..LTDQFFPI......FFIQFAMLCLSYFIRS.HWFFIL.....IQLFAL.............-YLSGIALIWDL.........................SVLLGLHRFVENFSFLLLLSYGFYLVm...................iWVHRIQPSQYQRSLALANLLII..............-LSSLGFYTL................................-FGQYELEKIRYLPILSLGLPILW..........................lALFMVLRIHNQFSLI.AQLILLAFA...........AVLIFYGYFEIFICIAILSWALPQHDKI.VYGFALVTLALTLWFIYYALNVSFLVKSLSIFSSGLILLVLTWVLHK-f.............
V4LGW7_9GAMM/55-330                  ................PWYLRTLIGFSAWFSSLLLLGFVLEI--GLVDDE......VGYIALGLGLLLAAIVLSR...........-VIDNDFSNQTALACNLAG.....QCLLVIGIAG..TMPGDEFKm....aLVCLILLNALLIPLYS.DRVFRT.....LAPMIM.............-VAAMVALLYAY.........................QVQAVLPLVVPALAALFLWMVSNEDW....................fS--VNGHDQWARPLMAGLLLGLfg..........ctLLST-----Vyvlp........................eladRFEFYPRPWLSTLGIGLLLLYAEY...........................RFLCADVFGGFWTLP.AISAYGMTT..........lILLATLPAPGIGLSVMIMLLGTARGSPT.MAGAGI------------------------------------------g.............
H1ZAR5_MYROD/37-363                  ...............v--FLKVVAILGSLLAMGFFFGFLFLTIGDSLGY-......ISFLLFGVVLYALSFIGNK...........-KTEPALRDGVFVATYISAfvcviAAGIDFGWRE..SNN-----......LLSVIVLSFGGFMLFK.SKIIQF.....LSLIGL.............---YYGLVYYLG.........................FIHLGYGALLLFWLLLVGLYFMFDKEv..................elKTKYSFWSQRYNAILNALFLIF..............---FFEIIQDnislidps...............nwinrsrffDYHVVGHRIYLGFVGIVLIVLTYW..........................tIKQIGQRVTLPQPLL.ITGISSVVIlg.......maFFMHGFGMP-LVVSFFLLVWSFQFRFYK.GIVLAICTLLLSLGAYYYYLNVSLLIKSLILMGCGLFFLGLFVIYNRW..............
E3E917_PAEPS/496-569                 ......ymfmnifyfv----------------------------------......-------------------...........-------------------.....----------..--------......----------------.------.....------.............------------.........................--------------------------.....................----------------------..............----------................................------------------------...........................---------------.---------...........-------------IVTWMVFAFIRHKQKsEAITSVVFWFIFIGFKYYDLLWTLLYKSFTLALLGIIILGITWWFDR-r.............
B1XZD6_LEPCP/32-362                  ................PWPVVLMSALGAWLVGLPMFGLITQLFLGVFDSN......LGAYLIGALVLAAAVAALR...........KPGHTLFVEQLAVAGLVAG.....AGYLAIGLTR..QLPTSAA-......AALLATLALWLAVLLR.QNWLRM.....LLGAAAc..........agVLIAGLDLILPR.........................GGPASLPRVALLLHLLLAVWLLAPRVvdalv..........aqrsapPGALPRSLAWLEAVGTGWLAVT..............-LPALAVLAGfdgwarsgp..............dravqgfgwA-DLMPLLSVLAALAAAVVGWRRW...........................----------PPLRA.PWWLGVAAT...........LALLAWFMPTLGAVLLALAVCAVTRRSW.LAALALLTGLWIGSAFYDQLTWTLAQKAALLAVSGLWLGLLAAWGQR-s.............
U1YCQ8_9BURK/322-639                 ................PWYLRVIKLFLYLLLPLIILLYLGVSLELSLE--......-ALGVLGGIMALVSPVLFA...........-KAHTVPSQDLVGG-WVAC.....ALLLLSVPVM..DLRYPWPLe...asAMIAVVISTLLYRLAKgQFVLRM.....LLVIWA.............-LAAIEFLVIERlfdr................wtmmpYWVLEMPAAFMFFAAL---------Wlg.................hlYLRGERKPHFWLPLFWSLLLAS..............--QIHLIWAGtlfy.......................smpfwDESRPYLTVAGFLLAMAPLAILAF...........................---YWRGWRDQPLVY.GIALLGMAA...........LCAVWTPYPPVALALSWILVAYAWRYLS.LLAVAVAMGLFCLWRLYYILNISLLDKAELLLATGVGCLVFAYLGQ--ls............
B2KEA1_ELUMP/31-348                  ...............s-LIIKIILGIGAFVSAIFFFLALTTVLVFSRSQG......FAFAALGLIVMVCAVAAKLtv......knlSPGPRFFVDQLLLAAILFG.....KGCILFGILT..HFERHRSYiivdvgMITCFFLAAVPYKFFD.SAADRF.....ISVFTF............mIFVYLKMFAFGG.........................IWFSSNFVMLLSFIIGFFCFFL----.....................------RKKDYYPIAWAMVLSM..............AIPAVCNIFI................................-----VYKAYSAYMSYSAVMLNVYkiili.................lflsvMFALDAYLKGNLNKK.TALILPVLL...........IFSLPFNLP-VIYALALLVLGFYFSDLK.IKILSYIILCGGIAYLYYSLHITLLAKSVLLLVSGLVLLALRELLKRY..............
A1S5M6_SHEAM/29-345                  ................PLWLTLLTGLSGWIAAFFFLGFSVLLIEEFSRFD.....dKMALAVGLIYAAIARGIYS...........QGKGVEFLTQLGFAINLAA.....MLATLWGLAH..YFDN----......PGVVYWLSGACLLALN.GWFCRYgvdgqLSVLGA.............------LVLFAQ.........................AFDSVKCVAWVLPAMLLGLGLVNGLWqp.................wiRLQLCGLHLFARRLSHGMVFMV..............LALPLVLDEQllylgag..................sifagqdGWAFSIAKAASYLTFIIFCAAILW...........................--------RLKVPVL.GLVMGTLG-...........LTLLFSQFSGLALAMVLWLFGWQRRERL.YVLLASMAALLYFSAYYYELSLTLLHKSMVLMGLGILLLLAGFVLSR-r.............
Q0K6G7_CUPNH/32-365                  ................PWAVRCLMGAAGWLGALFFQLFLVGTVFVAAREN.....gIAMAVTGLAMIALAALLYW...........-RGGGIAAGQFALAVSLSG.....QGMAVFGLVE..ALGFTRVTes.agfWAGLALFEAALALLVP.NRLHRL.....LCAVGAw...........iGLAGAMHLVLAGsep..................ddwlLLTWSLGWLVPLGCALVTGFTLAEA-.....................RLCAAGRHTLLEPLADATLLFT..............----------................................--------LAVALVVTGMSHPLAWlggpeagriplahwvagglatvvlagfALAECRRLALSPALQ.GAVLAGVAA...........FGALMAAAPAVVAGVLALGLALRRASMP.WLGLGIASIAVGFIWYYSALHWTLLAKSATLAVAGALLLAGRYRLLR-t.............
Q1D0K8_MYXXD/43-356                  ................PWFVKAFAGVGAWLSAIFVLSFFACA--GLWEEQ......VVMGVVGLGLCAGATMLRR...........-TLRGVFVEQLALAQCLAG.....AAMASASFGI..ETENENVA......ATLVLVISGVLLFVYP.DAILRF.....LSTLGV.............-VGAAGFLAWHV.........................VGGFALDLLILGCAALMYFLFLEQA-.....................RLRRGTPGELVGPVAFA--LAC..............AIPGVLLARGmrdv.......................arhlfDTVSALPDAVLTLGLTVLTLYTAW...........................RVLRELALEPTGVAG.AAVFAALTL...........VAVLTPHTPAVITAVGMLVLGFHRRSNV.LLGLAVAYLLASGSWYYYDLGLTLLAKSLALMGSGLVFLGLRSFLLR-r.............
A0KLV5_AERHH/27-329                  ................HWSSRFLLGMVGWIAALFLLFFLFMSFSQLTRDA......DSALLMGVVLMVIAFCLNR...........FATRSDLWDQFVLALALAG.....DAWLLYGLLD..RLDLHSAP.....lWFGLALLSLAIAALFE.HWLIRL.....FHSFAA.............AILLTLGLACLG.........................LQLLALPLVMTAVALCWLQ-------.....................AERDPLRHQLYESLTLGLALSL..............LVLGRLHHPL................................-----WDGGASMLDELGHSRLPLW...........................---------LNPLLC.AALLLGLMVrlklpllyglpLVLISALIPGMGAGALVLVLGFYAGSVG.LMTLAGLLLVGFGSLYYYDLGLTLMTKSWLLLGSGALLLGARQLLKRL..............
A0A0B5RX03_9FLAO/36-348              ..............si--IIRVISVMGSLLGLALFIGFIAMVASDFFNNN......TAFIIMGLLFLGGAYALNR...........-SKDSAITDSLVVSFYIIG.....YAFMTYGFGD..MFNQM---......ELVGLFFSLLTLFLFN.NQIVSF.....ISSVGT.............-LIALQYVLYKF........................dITPFYYIYLALVVVLTTYLFWQEQKV.....................RTTITWISKKYLPIFTACFLYT..............-ITTASLLRNqaf.........................syhsIELFSSMRFVFVITVLALIIATVY...........................LIIQKMKITNSTVKV.AIYLIVILF...........NVLITLNYVVFGITFLYMLWSFMRQYKV.GFALSIATLIWAMGMFYYDLGISLLEKSLSMMTIGVLFLGVYYLIQK-..............
Q1LIF8_RALME/31-368                  ................PWPIRLLMGAAGWLGALFAQLFLLGSVFAVTRGN.....gPAIAITGLLMIGAAILMYRt........tsQDSARIALGQFALAASLGG.....QGMVIVGVGE..SLGIDRLSqt.avfWLGVTALEAVLFVIVP.NRLHRF.....VAVTGGw...........sAATIALYIALGGsmr..................npflMMPLTVGLLGVLAMAAVMVFVLNEA-.....................RIAARGTHALWEPAADATLVFG..............-LSSALIITGtalpse....................flfdgiRHLQTPGNWVPGVLVGVCLVGF--...........................AQIEGARIRCDAGIR.IGLMVLAVA...........FSGLMVMAPAVTAGVLALAMALRRASLP.WIGLAIAAILLGFIWYYSTLQWTLLVKSVTLAAAGVLLLAARLALTRM..............
A9HVM5_BORPD/350-681                 ...............a-WYVQGLLGLSAWLATLLLLLFLAVS--GLVQTQ......QGAMVMGLVLCAAAVAVLR...........-TDAGPFWRQCATAMGFAG.....QILVAFGLSQ..SASLSSA-......CAFVLLLGVAVYALAP.DALLRF.....LSAWMI.............-ALALAGLIWLG.........................LVPGLMNDGLLDMWL---DFDTVRATfvwlpvavagawtaaaafcvgHRLARTRPNVLLPLAWA--FVL..............AVQGMVWMAGgvsltq...................lpviwqlNPVTALLTVAAVLLPVACALAVLW...........................----PRRRLLTAGVL.WGVPLGLLA...........LALCWLPSPGIAFALAWMLLGFGLNRSR.LTIFGGLSLLAYLVVYYYQLQVPLLDKALWLGGAALLMFFLRALVWL-v.............
Q8A6Q3_BACTN/6-311                   ...............n-LTIEVLSIIGGVLTAIFFLGFLVLS--SILRSE......TSCLITGSILIITTLFVNR...........-LLTKPFLDAMNITCYIAG.....CILAGYGMNR..NMDVL---......FIVLIGISVVTMLLSK.GFILTF.....LSVISFy...........mALFGEITNLFSS.........................LNPLNVAAVPIIAIFLFVNLSETKI-.....................LSYTNGDLSKYKPIHSGLFVSC..............VLSLAGLSVN...............................yLTKSTNDWIISVFMLVGI-LLMVY...........................KIVQVMQVKSPVHQV.CIYLLCILI...........CFP-SLHAPYLSGSILLILICFQYGYKA.ESAVALLLFIYSISKYYYDLDITLLTKSITLFFTGIALLIAWYIFTQ-k.............
C9R5Y4_AGGAD/306-664                 ...............s-WALSILLIFAIFIGIVTALIWLFLTLNVSEP-K......TGLLILNVIVLFIALGLHFg.........nPHAESHMSIIIGIFFFMGY.....NLLAGYFLAD..VFDSYGEGaltcdvPLLFTAIISMLYFLRK.ENWLRT.....LTLVIV.............---LGVWHIYLTdcstgd.............lshanrIEYSYVPLYFVTMLGCVIAFFVQNI-.....................YGENSKVRVRITPVAWAFLLF-..............SIGGWAFSTDnflslfvvyv............pgtvdalpeiDTFSGFFTMITAGFYSRAVLGLGWtipflv..............cftplvtYFAISRFFSLKTDEK.MCIAAILAL...........FTFLFVGQPSVLFFVTLLLITYFVQSRT.LFFIGVLSLVGNLAIYYYLLFIPLLYKAFLLLFFALLFSAVAIYLHRK..............
Q7CJX4_YERPE/394-725                 ................PWYIRTAFAFGGWIAALILLALLILL--GFVSGMfdnlnaGTIIVVSLIGGAFAAFLLT...........--RPGMGIQQIGLVWAIAS.....SIGLYSGIIL..IQDSSSRLml..mqSLWFIPVLAVLIVVFH.NDMYRF.....LATGTLv..........fmSIVTTSYALIWH.........................LAPDNQQLFFFIPILIVTVIVMLILWlic...............neiKLLATVNAPLIHPLMYGGIGG-..............-ILVVCLHSIqmgnih....................efywmsDRGLYLEQSLSYGIPAAFLLFTLI...........................QWVLHRSKLKPLWLI.AAVVTSLA-...........----AYFAPGMGFGLALLLIARYQGNQW.LLGVAASFLAVYTSGWYYFLGFSLLYKSLLLIGGGVLLLVLAGVLNR-v.............
A0A088F1B2_9SPHI/43-355              ...............i--AIKILSILGIILSVLSFLAALLFL--NLLDEK......LNLIISGALLLILSIVGLK...........-KYSSIIIDTASITLYAVG.....GWMLIYGLDT..NNTNLI--......LVLCIVISSCTLVIVQ.RYLLSL.....LNMLCI.............-IYAIFALIANN.........................F-ENMIYFAFANALIVVALFLISNHEa..................fiISKRNFISQIQQPLRTALFLST..............LATTAYIVLShf...........................dtyENSVNTSSIALYLTSITYAVAIIYm........................ihKIMLKLGITNTKLRI.TIYTLSLMI...........LIA-TIINPGISASIFLILLCFYYQYKF.GLSLSIIAMPFFLWHFYYNLNFTLLTKSILLLASGALFIAAYFVI---ni............
D6CWQ2_9BACE/6-317                   ...............n-LTIQVVSIIGGILTAIFFLGFLALA--RILRSD......ISCLIAGSILILTTLTISR...........-MVVRSFLDAMNITLYIAG.....CVLIGFGINA..SINLL---......FITLMGISILTFLLSR.GFILPF.....LSVILFn...........iSFFGEAAHVFSS.........................FYPLQIAVVPILGVFLFTNIFENKLF....................eCIGTENYLSKYKSFHFGLFVSG..............IVSLGGLSIN................................----YMISETNSWLVSCILSVCIWigil...................imvqRIMQVMKVDHPVNQV.GIYILCIVI...........CLP-TVFAPYLSGSLLLILICFHYGYKA.ECAASLLLFIYAVSKYYYDLNLSLLTKSITLFFIGIACITAWYFFTQ-k.............
I4MQV0_9BURK/198-363                 hmltrqegfdweftrd----------------------------------......-VSLVFGLATCAIAVWVDLr........crLASDPRDRQDFAFWLYLFG.....AIMFWCGLSF..RESDSELS......KLGYALINVVLVFLGA.AIARRV.....FTVFGA............iGVAGYVGYLSYK.........................VFADSLLFPFVLTLLGLGFVAL-GIW....................wQRREARIHARL-----------..............----------................................------------------------...........................---------------.---------...........----------------------------.------------------------------------------------agwlptalsplaeg
F2IGY4_FLUTR/42-352                  ..........aleylv------------FIGALLTLGLFTGATFQIIDNPs....sGFFLIWSILLLGACILLHI...........------FVNQRLVDAMAAG.....AGVFGFFSFN..AFLYS-LHwkdshvGLISVFLLIILILVSR.KNLLTI.....LGIVGLf...........wQMNWLIDEYQFP.........................YYTFKLIVMLFTLILALLIYFE-EAV.....................LVHFIKWSYFFNYLKNGIFVAL..............-TSYYVLGFInwnhw......................rgtfqEPLWYNRAMYVELL-LLAFALFVW...........................---QYRRMKDRNIPL.WVVVFLPLS...........LFLLGVFSVKIAFFLLAFLAFLFTRSIF.GIVTSALGLIYAVIHFYYELDWSLMHKSLLFMGLGALYLGLYLVL---i.............
F9TAA5_9VIBR/28-341                  ...............a-WPIKLLLAISGWLGGLCLLGIFFGAFTLFFQSA......VASAVVALIMFVAAQRILS...........-ARNNEFLEHLALALSFSA.....QVLFVWALMP..LDQLQVI-......LFLFALLQAGLAVIMR.SMIHRV.....WSTLSC.............-CLALSALLISC.........................GFSYLLSSILLAPMV---WLSLN---.....................EFRFPALYRLVSGIKYGLVISI..............-VLLMCIQIFraeves....................alvsisDTTFSFPLWVAPITYVLSIFVTAW...........................YLFHFHQVRLNSIVA.KLGGIFTIL...........VAVLTCMAPGIGASLMILITAFANSDRV.MMGLGATALLAYSSTYYYMMETTLLFKSGVLMSVSLIMLFSYLVFNK-v.............
B5E9I7_GEOBB/30-347                  ................TWYIRAMLGFAGWIGAWFILGFVGTSFAMVMRSA......GAASFAAILCCGGAYAIFR...........LPSKGDFAGQFGLAVGLAG.....QALFAVAIFK..ELSPSISL.....gCFIFFCVEALLTVLMP.NFMHRI.....FTTVAA.............----VAALFYAS.........................VQAGLHGVVLSIVAAACAVVWRG---.....................EMRLAARAELWQPVGYGLALGV..............--LQLAAYSA................................--------AGEAMLSGLHHGEADWlqrhgndvgta.....lvaviflavtvQILKELDIEVSGKEG.IAIVSCMAL...........IMAASFPTHGLAAAALILILGFAGGNRV.LFGLGLMAVASFLSHYYYQMRETLLIKSMILAATGTLLLVARWGLLR-l.............
A0A090AEM7_9GAMM/42-352              ................PWFINTLIGISAWLAVTPLLVFLFLI--QLTNTA......VSAIGVGIIFIVGTVSFRL..........fYKEDTLFLAQFALALNLTG.....QLLFIGGLWV..QTDMLMA-......ALASSVLELFLFNFYQ.SNIIRF.....ISVLIF.............-IASLIVLLNEL.........................HFYQGIHFIILATALGSLWCWLKESQ.....................HQLSEIMVELYPPLGYGLVIALf...........imLLPS-----Gli............................gvPGIPLITWSFSTVGLVMLLLGLES...........................ILLHNHNFSLASANG.IILLGGTFL...........IGLLFYQAPGIIATIIVMVLGFQRGNRV.LMGSATLFFTVFLVAYYYHLELTLLMKSITLVSSGSALLGLRWLLKQ-l.............
R6E8U4_9BACE/6-315                   ...............n-LTIQVVSIIGGILTAIFFLGFLALA--RILSSE......ISCLLVGSLLIITTLTISR...........-LVIRSFLDAMNITLYIAG.....CVLVGFGLNY..NMNIL---......FIALIGISMLTFCLSK.GFILPF.....LSVIAFi...........iSLFGEITHIFSS.........................SYPLQIAVVPVMAVFLFTNLFEVKL-.....................LARLGNNFSKYMPFHYGLFVSC..............LVLMSGLSIN................................----YLTQDMNYWIISCILSVFIWigll...................imvqRITKVMQVDNPVHQA.GIYILCIVI...........CLP-TVFAPYLSGSLLMILICFHYGYKA.ECAASLLLFIYAVSKYYYDLNISLLIKSITLFIIGIAFIAAWYFFTQ-k.............
A0A052II30_9BORD/358-689             ................PWYVQGLLGLSAWLATVLLLVFLFFS--GMVTSD......QGAVVFGLVLCAAGVAVVR...........-AAAGPFWRQCAIAMAFAG.....QLLVLFSFVG..NDSIASA-......SLFIVLLAAAVYALAP.DVLLRF.....LSGGLI.............-AVGMTGLVWQA.........................LQPDLARNDMLEMWLALDVLRATFLWlpvavlgaw...latlafcadRRLARAQPHFLEPLAWA--FVV..............AVQGMVWMAGgvgvdq...................lpalwklHRLTALLNLAGALLPAAVAFWLLW...........................----PRRQVLTRSLV.VITPLALLV...........LALFWLPSPGIAFALAWLLLGFGLNKPR.LTGFGVLSLLAYLMLYYYQLEVPLLQKAAWLVGAAVLLFLLRVLVWL-v.............
I3U7T0_ADVKW/1-287                   ...............m----------------------------------......-------------------...........-------------TLMLVG.....LLLLAFEVFS..GTYIDYADrs..lpILGLIVGLLILYHMYH.IPWFQF.....MCAVAA.............--LVLFAILWPQyspglaldradtglsgyhrdaewvsFLNELAPVYIVLATVIL---------.....................MGLPAVWLRRYKTLAWAL-LCV..............PLGAYVIHMSgvsysdhqsvqq.......gqnmlamvlskwhL-------------------PTRFpmvylcnl..........vfallpvgvAWLSARRRRVFGADQ.TVVLLVLLV...........LGVLWGDLPGVQLGLLLCLLGYELHYRS.MLVVGVVSIVVFLAQFYFQLHFLLLDKAYFLTAQGAVLLVTALLW---yrt...........
B8J1C2_DESDA/418-746                 ................PWYVRLLLALGGWLAAILFVCFLAFFVFETMQIIayeeagIFIASIPVLLLGRSMLVKN...........----TIFSRHFGFALAITG.....TVGMSISMFL..TVNSFMSA......CFLLALLLVVVSSLMQ.TPPYTF.....LAAMTVv..........aaVSFGTSSLVFEE.........................LGQW----------------------.....................QVESLGKIIFYLPLIWWAAVSL..............GLARFCLHEKtwrg.......................rgtspNADAWFFGAYAGMLICQLASLGIWqqfmlpfpalrg..aygmgmgaalgigYLAISLSRKRHGFAR.AGVLLAAAA...........SFVLAWHLPGAALALLGLALARQMTNMA.MQGFVLTYLLAYMIFYYYTLAVPFAAKALYLTATGIVLLLLALSLRT-w.............
H8MMH5_CORCM/43-360                  ................PWFVKALAGGGAWLSAAFLLSFFACV--GLWKEE......VALTAMGLVLTVAAVLLRR...........-TSQGPFMEQLALALCMAG.....VGAFLVGLAQ..LEQNTLTV......AFAGAVASVVLLAVYP.DLILYF.....LATVGL.............-CVSVGVFALDA.........................VGGAGVDVWMLLCAAALSGILLFEP-.....................LLRRGQLGPRVGPIAFA--LAC..............AVPGWLLFRNfesaqe...................gfryvfrFESEFVPSAYLSILLALLLGWTGW...........................RVLRELGLSREQRVW.VPAVCALVL...........LTVMTLNTPGVLVAVLMLTLGFHRRSRV.MLGLAVAFLLTFGAYYYYDLHITLLAKALALTGSGLVLLGVRQFFLR-r.............
G2PP97_MURRD/42-352                  ...............s-LAIKILSALGGILASSAFIVVLFLL--DVLDSE......WSSIILGIVLIGTAIGINK...........-KYETLIIDTFSVSIYVLG.....LILFILGMAM..HHNVQEGH.....iAFLIVLIALSSLFFTQ.NYVISF.....ISVLAI.............-GASFLFLIISY.........................HIPDAIHGYVLFYATALSYCFLNEAS....................fLTAHPKLAKLYGPLRIGLIFSL..............LFGLVVIGKN................................----GLVPISKNLIWMSSVASFFFily.....................lasHVLRTLQVRSTKNKW.AAYVLCFLT...........LLP-TLFAPAISGALLIVLLSFLVNHKT.GLGVGIVALVYFVSQYYYDLNLSLLTKSIVLFSSGVVFLVFYLFFTK-k.............
F4GMT9_PUSST/325-650                 ................PWYFSLLRITIMGLAAILVIAFLFVTLDLEYE--......-QLWVIGLVVCGLGLLALR...........--SGGSIMGEFGTTLTVAG.....LFMTGVGLFD..LNEIGSFS.....rAGGIVLMGLAVYCLAT.GAALRF.....LCAFFV.............-LVLAYQLTWPD.........................YLDAMPLDLLDGGSASTLAYFPAYLRlwwlav........aavlalvVAQRAGKQAFWLPLAWA--LVC..............LTQAAAWLAPaptvlg...................ldgvtqqAPGLLVIWLACALLPVLSLAALMW...........................-----RAGHVPRWLS.VSAPLALAV...........ASLGWLGAPGVSMALLWLVLAYAMGQRA.LLVFAVLSLLAYLSRFYYQMDATLLQKSLVLGLTGGWLLLSWFALR--ak............
A8H3N1_SHEPA/44-367                  ................PWYIQLMQSVAAWVASLFILAFSISFFNLFFDDLd....tGFATAVGGFYSVFALVIYR..........sISDKQLFLNQMAFALSLCG.....LLSLGYGMTD..WFSLVHNKeiglawYVTFGAILLLQWYLIE.HTSHQY.....AMSFGI.............----ISCLIGAS.........................YELGLLELMPTLIMILFAGVWLN---.....................HSKTGKHFAAMGAFGYMLAIWL..............VLIQLPLLINqsdffg...................rdefplvAEWANVLSVISTFIISVVLLR---...........................KILQPLSVSLTSKLG.LSISVAMLV...........LAGLSMVMTGLSASLLVLLIGFYVRERL.ITALGLMGILSFIAWYYYNLQLPLLDKSIWLAALGVLLLLAKLLLNK-l.............
A0A077KNR7_9FLAO/42-352              ...............s-LSIKILSVFGGIMACLAFLGFIFMV--QVFESQ......IGIGILGMVCIAGSSFISR...........-IAGKTIIDTLSVSFFITG.....FSLLGIALST..EGDSI---......YPVFIILALCTLFLAQ.NYILSF.....ISVLII.............NGSIFAFAQINQ.........................IFTLTHAIIILQALIIT-FLFLWEAK....................iITKNKVLSKLYDPVRTGMVFSF..............IVTLAFLGFKsff..........................rigNEEHYYYGSIPSVVIVIAILYVVS...........................HLFKTLQVTDTTYKI.FLYVLTALF...........LLP-ALLTPTIPGAILIILLSFSVNYKT.GFVLGIIALLIFIGRFYYDLNFTLLTKSILLFTSGIIFLAIYFFTHK-k.............
R5U988_9BACE/6-311                   ...............n-LTIQVVSIIGGILTAIFFLGFLVVA--SIIRTE......TSSLIIGCLFIITTLTISR...........-RLTVPFLDAMNITLYIAG.....CALIAYGLNK..STNAL---......FIALAITGIFTFFLSK.GFILPF.....LSVILFi...........iSFLGELAYLSSS.........................IQLLQIAVVPVLAVFLFTNLYERNIL.....................TGLKENLVSKYTPFHSGLFVSC..............ICLLAGLSVN................................YGIPAPYWLLSIFIWIGILL-IIQ...........................RIMPVMEVTNPVSQI.GICILCILI...........CLP-TMFAPYLSGSLLLILICFHYGYKA.ECAAALLLFIYAVSKYYYDLNLSLLVKSITLFFTGIIFMIAWYYFTQ-k.............
A0LJX9_SYNFM/32-349                  ................PWFVRVMLGIAGWIGALFLLAFIGIGFHSLIENW......PGAIITGTLLCAGAAMLFR...........SGLRADFASQFALALSFAG.....QALICFGISE..LLRWDFFA.....vCLAMTAVETFLFFAAP.NFLHRV.....WSAWAG.............--SFALALAFWD.........................LKLSTFAPGIVTAAFAFLWFS-----.....................EFRHPRRGALLRAGGYGLAASI..............-IATVIMLSGrsegvlwws..............ravpapgndLLVWLGLGLSGTVLIGVSIRLLYW...........................-----ENVPLGSRPG.KAVLAGAGI...........LAAASLKAPGLGPCVAILVVGHAAGNRR.LAGLGVLALLGYLAHYYYVLDATLLQKSEVLAGVGLSLLIARLVLLK-c.............
W0P6D6_9BURK/370-706                 ..........llflis-------------FGFIFLLGLALIA---VLE--......IPLTVAAGVVLVVGLLAYF...........--ARGGAWRVSGATLLLVG.....LLLLAFEVFSgsYFDYDNRSl....pLLGLVAGLLLLYHMHP.IAWFQF.....MCAVAA.............--LVLFALLWPQyspgwaly.........ggdqslgyYYDVEWQVFMTELAPLYLVLATWML-.....................LRLSEKWQRRYKALAWALLCVP..............LCGYVFQMSGtyfglshmaagg........rdllalllakwrLPAPLPFVYASNVVLALLPVVVGW...........................--VVARRHQVPAAEQ.VLMVLVLLG...........LGLLWGGLHGVQLGLLLCLLGYALRYRS.MLVLGILSIMLFLAAFYFQLHFLLLDKAYFLMGQGVVLLVIALLWRR-l.............
A1K370_AZOSB/32-367                  ................PWPVVLLTGLGAWLAALPLLGFVALA-TDLVDSG......VGAIVVGSLLLAAAVMVLR...........GRGVSLFIEQLAVPGLLAG.....AGLIALGLLD..SSSERVA-......AGVMAVLALGVAAGVP.QAWLRA.....LLGAAAa..........vlIWLVITDLAYDG.........................LGFLVPPAAVLHLQLLVWIAALQGQQr..................alAEGRAGVAAALEAIGGGWLAAV..............-LAAFALWSGttfllganlgaaaavelaealadgpraggaglAGGWAAL-SAVLALGAGVWLARRW...........................----------PGLRQ.AWCAGVVLV...........LAGLALFLPALGAVLLAAAICAAGRRAV.LALTALVAAAWIIGAFYYQLAWPLATKAGVLVGAAAVLGTLAAWGAR-v.............
M1FL62_9ALTE/31-347                  ................PWYILVFMGFFGWLAALFLFLAIALLFFFDLELDrffespLLLWTIGLLLIGVAFWLLR...........-SAASEFVRHMALAFSLAG.....QGFVAWGSFG..GADAIGA-......TLLITGFQMLLAVFMP.DFIHRV.....FSTCVAa...........lGLLVFVELPLLN.........................VVAGGVVLVFTGWVWLH---------.....................EFQFPRMSPALRAWGYGGGLAL..............VTSRSEVVLGlnwsv......................tngmlNTLPTIYGWLATLLEGLAAVYIVY...........................--SVCQRLKTAARVQ.ILALCALTA...........LVLASAVAPGLLVCMMVIVLGQTGSNTL.LKGIGIAGLLFYASAFYYQLHATLMVKSQVLLATGLLLLAVRWLMLR-l.............
Q9CM56_PASMU/289-634                 ................TWHIYPLFILLIIFCTGLLLITLFFS--FGLEDE......QDLIYPSILFLIIALVMHF...........NQKEKADWFDIAIDMFMAT.....GFILYFIFFL..FDGENDLY......LALMAILSVFLYQLRS.SNWLRF.....LIASLFiiaflvyigffdlRWYAYYEEHLGQ.........................FVLSAQQWIILGGLLLYYFFSL----.....................-SEERPYTIKLLPIAWAMLLVG..............----LAMNLDifnrwtfldtaqqtpemsdlndwfhvitgyffTALTSDTWLIKSLHLLISITPIIF...........................FVLISRRFELTKFLY.ASVLLTLLA...........LCLGFIAVNETLACISLLLLAYLSVSRV.LFALALLGVIMNLSYYYYLLSIPLLHKSFLLMGVGIVLALVTFVLLRY..............
A9BVL7_DELAS/34-368                  ................HWAVVLLTALGAWLALLPLLILFAFALSDWIERG......AGTYVIGAMMLAAAVAVLR...........AEELPVFLEQLALPAMLTG.....AGLLGFGLAR..DLSGQAA-......GAIGLAIALACTAAIP.RPWLRV.....LLGAAC.............-ALLFCTMLWPDnd....................pstLYAGLPTWVIVHAALLLWMLLLAAQWra................lgqSAAQTRMAAALEPFATGWLLAV..............-LAGLAFLSGrsfmvagalgg.........glagelaqeaapN---ISMGVLTQAGSAVLALAAAW...........................----FAQRAWPTLRQ.PRAAVAAVV...........LAVLSAFLPWLGACLLALAVTGTSGRWR.QAAAAALAAAWIVGSFYYQLAWPLATKAMVLAGCGALLGLLAWAGPR-a.............
Q7VSG6_BORPE/349-680                 ................PWYVHGLLGLSAWLATWLLLLFVAAS--GIVASK......EGALVAGLGLCIVAVAVLR...........-TDSGPFWRQCATAMGFAG.....QILVMVGLWD..SASFASA-......CFFILALGAVVYALTP.DLLLRF.....LSGWMI.............-ALAGAGLIWRG.........................LTPGMGDKQLLGLLLEFDALRA---AfvwlpvavvgawgaavafslgHRWSRIRPQQLDPLGWA--LAL..............AAQSMVWLAGgvtamq...................lralwalHPSTAVLTVAGVLLPVAVALSVLW...........................----PRRRQLTAGML.WGVPLALLV...........LALFWLPSPGVAFALAWLLLGFGLHKPR.LTMLGVISLLAYLMIYYYQLQIPLLDKALWLAGGALLLFLGRLLVWL-v.............
#=GC seq_cons                        .................WhlphlhuhuualuulhhLsalhhs..thhppt......huhhlhGllhhssuhhlhR.............tts.hhcphuluhhluG.....thhlsaGlhp..ths...........hhhhhhlthhlhhlht.shhhRh.....lushsh..............hhshhtllhts.........................hhshhhshhhlhhhhhhhhhhh.........................thtttthtphhpPlthuhhlsh...............l.thhhhhs....................................h.h.hhsshlhshhhhhhha.............................h..hphphsshhh.shhhhslhh...........lshhhhhsPuluhulhhllluathppph.hhuhullsllhhlshYYYpLphoLLtKShhLhusGllLLshthhht+.h.............
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