GenomeNet

Database: Pfam
Entry: DUF4425
LinkDB: DUF4425
Original site: DUF4425 
#=GF ID   DUF4425
#=GF AC   PF14466.1
#=GF DE   Domain of unknown function (DUF4425) 
#=GF AU   Godzik A
#=GF SE   BVU_3708 from Bacteroides vulgatus, JCSG target GS13500
#=GF GA   27.00 27.00;
#=GF TC   28.60 111.90;
#=GF NC   24.60 23.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF DR   INTERPRO; IPR025219;
#=GF CC   A small family of bacterial proteins, found in several 
#=GF CC   Bacteroides species. Structure determination (NMR and Xray)
#=GF CC   shows an immunoglobulin beta barrel fold.   Multiple homologs
#=GF CC   have been found  in human gut metagenomics data sets.
#=GF SQ   32
#=GS D7IXJ0_9BACE/5-117   AC D7IXJ0.1
#=GS C9L0V6_9BACE/1-118   AC C9L0V6.1
#=GS E4W364_BACFG/37-154  AC E4W364.1
#=GS A7AHN2_9PORP/25-150  AC A7AHN2.1
#=GS A6L9X6_PARD8/8-131   AC A6L9X6.1
#=GS A6L9X6_PARD8/8-131   DR PDB; 2LGE A; 2-109;
#=GS A6L9X6_PARD8/8-131   DR PDB; 2LG7 A; 2-109;
#=GS F7M8N7_9BACE/10-132  AC F7M8N7.1
#=GS A6L6K5_BACV8/9-132   AC A6L6K5.1
#=GS A6L6K5_BACV8/9-132   DR PDB; 3U6G B; 32-132;
#=GS A6L6K5_BACV8/9-132   DR PDB; 3U6G A; 30-132;
#=GS A6L6K5_BACV8/9-132   DR PDB; 2LRG A; 2-104;
#=GS E1YRM5_9BACE/8-131   AC E1YRM5.1
#=GS D4V7L8_BACVU/8-131   AC D4V7L8.1
#=GS E5UZ61_9BACE/5-117   AC E5UZ61.1
#=GS D4IJB5_9BACT/8-131   AC D4IJB5.1
#=GS C3RFV4_9BACE/5-117   AC C3RFV4.1
#=GS A7M5D7_BACOV/10-132  AC A7M5D7.1
#=GS D7I9L7_9BACE/11-130  AC D7I9L7.1
#=GS C3QLC3_9BACE/5-117   AC C3QLC3.1
#=GS C6IN96_9BACE/11-130  AC C6IN96.1
#=GS E4MB74_9BACT/8-131   AC E4MB74.1
#=GS C6ZAP6_9BACE/6-118   AC C6ZAP6.1
#=GS F7LKH9_9BACE/9-132   AC F7LKH9.1
#=GS B5D4M9_9BACE/5-117   AC B5D4M9.1
#=GS D0TY58_9BACE/5-117   AC D0TY58.1
#=GS D7J7Q0_9BACE/9-132   AC D7J7Q0.1
#=GS C7XG79_9PORP/5-117   AC C7XG79.1
#=GS G5SUR6_9BACT/10-136  AC G5SUR6.1
#=GS B3JI94_9BACE/5-117   AC B3JI94.1
#=GS F7M0G0_9BACE/9-132   AC F7M0G0.1
#=GS D1JWX9_9BACE/5-117   AC D1JWX9.1
#=GS C3R372_9BACE/5-117   AC C3R372.1
#=GS E1WSE2_BACF6/27-150  AC E1WSE2.1
#=GS F3XYB7_9FLAO/10-136  AC F3XYB7.1
#=GS C6IUJ8_9BACE/8-131   AC C6IUJ8.1
#=GS Q8ABX8_BACTN/8-131   AC Q8ABX8.1
D7IXJ0_9BACE/5-117              .HSLLVAACLLAASCNREEIQPET..DKAGMYHITVAVTGT--SPKGSVHIYNLD....GVKFRNKrTGT---SAFSVD..ETFTDKVEYSTEKPVSQITVQGILYSKEN..ATITLQV----KKDGESVFNQ.
C9L0V6_9BACE/1-118              .------MALCFVGCSKDDDEPGG..-KGAMYEVTIEQSGDFRSFIKSVVVVANG....-TRLKDGaTGESLASPLILSdeELAVEKVTLTTTGKAIEFAVSGSVVDGEDgvVNEPMQWVVTVYKNGKEIEKK.
E4W364_BACFG/37-154             .HLFALCATLVLVSCGGSDDDPVF.nNTSAVYKVVLEASGD-DYTAEAIIINPDN....-VSIIDEtSNTDLKQSSVT-..EYFSGRKVYITSKEVKVISAQGIILSKSK..SGAILKMTV--YQDGKEVYQN.
A7AHN2_9PORP/25-150             g-IVALFLGLILVSCSDDDDQGGV..IDTGIHKIVVEQSGDIDAFELGLVFGAVNttsgPTKLYDE.DGKYLGESHSVT..RMEDAKVSCQTGDDAFFMTCAGSVTSTSD.vSGKKLKVLVTAYIDGKEVNQ-l
A6L9X6_PARD8/8-131              .SAVCVCMALCFVGCSKDDDEPGG..-KGAMYEVTIEQSGDFRSFIKSVVVVANG....-TQLKDGaTGESLASPVILSdeELAVEKVTLSTTGKAIEFAVSGGVVDGEDgvVNEPMQWVVTVYKNGKEIEKK.
#=GR A6L9X6_PARD8/8-131   SS    .XXXXXXXXXXXXXXXX-----S-..---B-EEEEEEEEESGCCSEEEEEEB-SS....-S-EEETTT--EE-SSEEE-CCGGGSSEEEEEESS-BS-EEEEEEEE--STT---S-EEEEEEEEETTCEEEEE.
F7M8N7_9BACE/10-132             g-IIALFLGVILVSCGNDDDNKNT..--TGVHKIVIEQSGNTDDFDLNIAFGAANt.sgVAKLYNE.NGEYLGDSYLVN..KVTENKISCQTGKEGSMMTCAGSVISTSE.qAGKKLKISVIAYIDNKEVNR-l
A6L6K5_BACV8/9-132              .SVVLLLAGFIFVGCDNERTENAS.dFQTGIHKIVIQQSGDTDSFEVSVSIGGADk.ggPAKLYND.KGEYIGDSYSA-..QIRTATMSCCTNGNAFFMTCAGSVSSISE..AGKRLHITVIGYIDDKEVNR-l
#=GR A6L6K5_BACV8/9-132   SS    .XXXXXXXXXXXXXXXXXXXXX-T.T---BSEEEEEEEEESGGGEEEEEEEEEEET.TEE--EE-T.TS-EEESCEEE-..E--SSEEEEEE-TTBSEEEEEEEEEE-S-..TT-EEEEEEEEEETTEEEEE-E
E1YRM5_9BACE/8-131              .SAVCVCMALCFVGCSKDDDEPGG..-KGAMYEVTIEQSGDFRSFIKSVVVVANG....-TQLKDGaTGESLASPVILSdeELAVEKVTLSTTGKAIEFAVSGGVVDGEDgvVNEPMQWVVTVYKNGKEIEKK.
D4V7L8_BACVU/8-131              .SAVCVCMALCFVGCSKDDDEPGG..-KGAMYEVTIEQSGDFRSFIKSVVVVANG....-TRLKDGaTGESLASPVILSdeELAVEKVTLSTTGKAIEFAVSGGVVDGEDgvVNEPMQWVVTVYKNGKEIEKK.
E5UZ61_9BACE/5-117              .HSLLAAACLLAASCNKEEIQSET..DKAGMYHITVAVTGS--SPKGSVHIYNLD....GVRFRNErTGT---SAASVD..ESFTDKAEYSTEKPVSQITVQGILYSKES..AIITMQI----KKDGESVFNQ.
D4IJB5_9BACT/8-131              .SAVCVCMALCFVGCSKDDDEPGG..-KGAMYEVTIEQSGDFRSFIKSVVVVANG....-TRLKDGaTGESLASPLILSdeELAVEKVTLTTTGKAIEFAVSGSVVDGEDgvVNEPMQWVVTVYKNGKEIEKK.
C3RFV4_9BACE/5-117              .HSLLVAACLLAASCNREEIQPET..DKAGMYHITVAVTGT--SPKGSVHIYNLD....GVKFRNKrTGS---SAFSVD..ETFTDKVEYSTEKPVSQITVQGILYSKEN..ATITLQV----KKDGESVFNQ.
A7M5D7_BACOV/10-132             g-VIALFLGVILVSCGNDDDNKNT..--TGVHKIVVEQSGNTDDFDLNIAFGAANt.ggVAKLYNE.NGEYLGDSYLVN..KVTENKISCQTGKEGSMMTCAGSVISTSE.qAGKKLKISVIAYIDNKEVNR-l
D7I9L7_9BACE/11-130             .SIICSFVGLILIGCAEEKQG---..VETGIHKIVIQQSGDTDSFEVSVSIGGADk.ggPAKLYND.KGEYIGDSYSA-..QIRTATMSCRTNGNAFFMTCAGSVSSISE..AGKRLHITVIGYIDDKEVNR-l
C3QLC3_9BACE/5-117              .HSLLVAACLLAASCNREEIQPET..DKAGMYHITVAVTGT--SPKGSVHIYNLD....GVKFRNErTGT---SAFSVD..ETFTDKVEYSTEKPVSQITVQGILYSKEN..ATITLQI----KKDGESVFNQ.
C6IN96_9BACE/11-130             .SIICSFVGLILIGCAEEKQG---..VETGIHKIVIQQSGDTDSFEVSVSIGGADk.ggPAKLYND.KGEYIGDSYSA-..QIRTATMSCRTNGNAFFMTCAGSVSSISE..AGKRLHITVIGYIDDKEVNR-l
E4MB74_9BACT/8-131              .SAVCVCMALCFVGCSKDDDEPGG..-KGAMYEVTIEQSGDFRSFIKSVVVVANG....-TRLKDGaTGESLASPLILSdeELSVEKVTLTTTGKAIEFAVSGSVVDGEDgvVNEPMQWVVTVYKNGKEIEKK.
C6ZAP6_9BACE/6-118              f-ALVTLLSVMFASCSSDDSPISG..EEGHLYSITFKVTGHS-PRGNAHLINLDG....-VKFKCE.Q-TGVSQSSVD-..EPFSGTATYTTEGLVKEMTVQGVLYSTEN..--GTLSMRI--TQDGKEIYHE.
F7LKH9_9BACE/9-132              .SVVLLLAGFIFVGCDNERTENAS.dFQTGIHKIVIQQSGDTDSFEVSVSIGGADk.ggPAKLYND.KGEYIGDSYSA-..QIRTATMSCRTNGNAFFMTCAGSVSSISE..AGKRLHITVIGYIDDKEVNR-l
B5D4M9_9BACE/5-117              .HSLLAAACLLAASCNKEEIQSET..DKAGMYHITVAVTGS--SPKGSVHIYNLD....GVRFRNErTGT---SAASVD..ESFTDKAEYSTEKPVSQITVQGILYSKES..AIITMQI----KKDGESVFNQ.
D0TY58_9BACE/5-117              .HSLLVAACLLAASCNREEIQPET..DKAGMYHITVAVTGT--SPKGSVHIYNLD....GVKFRNErTGT---SAFSVD..ETFTDKVEYSTEKPVSQITVQGILYSKEN..ATITLQI----KKDGESVFNQ.
D7J7Q0_9BACE/9-132              .SVVLLLAGFIFVGCDNERTENAS.dFQTGIHKIVIQQSGDTDSFEVSVSIGGADk.ggPAKLYND.KGEYIGDSYSA-..QIRTATMSCRTNGNAFFMTCAGSVSSISE..AGKRLHITVIGYIDDKEVNR-l
C7XG79_9PORP/5-117              .HSLLVAACLLAASCNREEIQPET..DKAGMYHITVAVTGT--SPKGSVHIYNLD....GVKFRNErTGT---SAFSVD..ETFTDKVEYSTEKPVSQITVQGILYSKEN..ATITLQI----KKDGESVFNQ.
G5SUR6_9BACT/10-136             .SIMVLCLSLALVSCGDDDHKNDHhgMRTGIHKIVVEQSGNTEDFEVNLVFGATNv.ngPARLYDE.NGEYLGDSYSVG..KMKSNRVSCQTGQDGFFMTCSGSATSTSE.eSGKQLKVTIIAYVNGEETNR-l
B3JI94_9BACE/5-117              .HSLLAAACLLAASCNKEEIQSET..DKAGMYHITVAVTGS--SPKGSVHIYNLD....GVRFRNErTGT---SAASVD..ESFTDKAEYSTEKPVSQITVQGILYSKES..AIITMQI----KKDGESVFNQ.
F7M0G0_9BACE/9-132              .SVVLLLAGFIFVGCDNERTKNAS.dFQTGIHKIVIQQSGDTDSFEVSVSIGGADk.ggPAKLYND.KGEYIGDSYSA-..QIRTAAMSCRTNGNAFFMTCAGSVSSISE..AGKRLHITVIGYIDDKEVNR-l
D1JWX9_9BACE/5-117              .HSLLAAACLLAASCNKEEIQSET..DKAGMYHITVAVTGS--SPKGSVHIYNLD....GVRFRNErTGT---SAASVD..ESFTDKAEYSTEKPVSQITVQGILYSKES..AIITMQI----KKDGESVFNQ.
C3R372_9BACE/5-117              .HSLLVAACLLAASCNREEIQPET..DKAGMYHITVAVTGT--SPKGSVHIYNLD....GVKFRNErTGT---SAFSVD..ETFTDKVEYSTEKPVSQITVQGILYSKEN..ATITLQI----KKDGESVFNQ.
E1WSE2_BACF6/27-150             .SVVLLLAGFIFVGCDNERTENAS.dFQTGIHKIVIQQSGDTDSFEVSVSIGGADk.ggPAKLYND.KGEYIGDSYSA-..QIRTATMSCCTNGNAFFMTCAGSVSSISE..AGKRLHITVIGYIDDKEVNR-l
F3XYB7_9FLAO/10-136             .SIMVLCLSLALVSCGDDDHKNDHhgMRTGIHKIVVEQSGNTEDFEVNLVFGATNv.ngPARLYDE.NGEYLGDSYSVG..KMKSNRVSCQTGQDGFFMTCSGSATSTSE.eSGKQLKVTIIAYVNGEETNR-l
C6IUJ8_9BACE/8-131              .SAVCVCMALCFVGCSKDDDEPGG..-KGAMYEVTIEQSGDFRSFIKSVVVVANG....-TRLKDGaTGESLASPLILSdeELAVEKVTLTTTGKAIEFAVSGSVVDGEDgvVNEPMQWVVTVYKNGKEIEKK.
Q8ABX8_BACTN/8-131              .SAVCVCMALCFVGCSKDDDEPGG..-KGAMYEVTIEQSGDFRSFIKSVVVVANG....-TQLKDGaTGESLASPVILSdeELAVEKVTLSTTGKAIEFAVSGGVVDGEDgvVNEPMQWVVTVYKNGKEIEKK.
#=GC SS_cons                    .XXXXXXXXXXXXXXXXXXXXXST.T---BSEEEEEEEEESGCCCEEEEEEEECCT.TEES-EEETTTS-EEESCEEE-CCCGGSSEEEEEESTTBSEEEEEEEEEE-STT.TTSEEEEEEEEEETTCEEEEEE
#=GC seq_cons                   .pslhlshuLlhluCsc--ppsss...+uGhY+IslpQSGshcSFcsSVslsuss....ss+Lhs-.sGc.lusuhSls..EhtosKsohsTstsuh.hTsuGulhStp-..uscpLplslhsYpDGKEVp+p.
//
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