#=GF ID   DUF4853
#=GF AC   PF16145.9
#=GF DE   Domain of unknown function (DUF4853)
#=GF AU   Chang Y;0000-0002-2418-3433
#=GF SE   Jackhmmer JCSG target SP17443B
#=GF GA   34.80 34.80;
#=GF TC   39.00 38.50;
#=GF NC   33.00 32.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch --cpu 4 -Z 75585367 -E 1000 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR032326;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   This family consists of uncharacterized proteins around 220
#=GF CC   residues in length and is mainly found in various Actinomyces 
#=GF CC   species. The function of this family is unknown.
#=GF SQ   25
#=GS E6KTJ7_9ACTO/1-129        AC E6KTJ7.1
#=GS A0A095X4Y6_9ACTO/57-194   AC A0A095X4Y6.1
#=GS A0A1D8B0E8_9ACTO/42-175   AC A0A1D8B0E8.1
#=GS U1RJ50_9ACTO/40-171       AC U1RJ50.1
#=GS U1QBB2_9ACTO/39-170       AC U1QBB2.1
#=GS A0A1D8B0C7_9ACTO/31-164   AC A0A1D8B0C7.1
#=GS A0A1Q5PTB5_9ACTO/39-167   AC A0A1Q5PTB5.1
#=GS A0A3P1SBI3_9ACTO/44-172   AC A0A3P1SBI3.1
#=GS A0A7Z0VSI0_9ACTO/14-152   AC A0A7Z0VSI0.1
#=GS E6KTE5_9ACTO/45-179       AC E6KTE5.1
#=GS A0A1Q5PT75_9ACTO/40-168   AC A0A1Q5PT75.1
#=GS E6KTE7_9ACTO/38-172       AC E6KTE7.1
#=GS A0A1D8B427_9ACTO/47-183   AC A0A1D8B427.1
#=GS A0A1Q5PYE0_9ACTO/20-150   AC A0A1Q5PYE0.1
#=GS E6KQY7_9ACTO/14-143       AC E6KQY7.1
#=GS E6KTE6_9ACTO/41-172       AC E6KTE6.1
#=GS E6KTE8_9ACTO/41-172       AC E6KTE8.1
#=GS A0A095YXX5_9ACTO/63-185   AC A0A095YXX5.1
#=GS A0A1D8B428_9ACTO/47-182   AC A0A1D8B428.1
#=GS A0A179B2Z7_9ACTO/19-152   AC A0A179B2Z7.1
#=GS A0A1Q5PVM4_9ACTO/20-148   AC A0A1Q5PVM4.1
#=GS A0A1Q5PUK8_9ACTO/39-169   AC A0A1Q5PUK8.1
#=GS A0A095YXX5_9ACTO/229-361  AC A0A095YXX5.1
#=GS A0A1Q5PTI2_9ACTO/39-167   AC A0A1Q5PTI2.1
#=GS A0A7Z1AIV5_9ACTO/99-238   AC A0A7Z1AIV5.1
E6KTJ7_9ACTO/1-129                   ...m-------FKRDVEPAIIRARNELLTR.DN.Y-.RNYRGNDFIYEY........PVGDQK....LYSLKSRAYDFD.EHDSVRVRAVFAGELEPLGFVCRERTYTDND.GTTDLLfVWTSERYGVVVKAMVAEN.WLTSTSYYTGYLRSDGSSA-d.......
A0A095X4Y6_9ACTO/57-194              ....QRQSIQAFQRDEEPKILEFRRRLAEA.GG.G-.-GVWEARSFGSAinketdqsSGHEQP....AWELVGQDVAGP.YVPVPEVERIGREV---LSETYSDYELGSDK.GGVRQL.SWSDPVNGGFLYVTVHEG.KVTLMRYQTGLRPSDGTTE-n.......
A0A1D8B0E8_9ACTO/42-175              krap----IGVYLSDAEPLIERFVDALAKQ.NG.GA.LGYDGSAYINGC.......gETGDEH....GIRVRSPGLKIL.MTDAMDLRALSEQILEPAGF---TPPDTFAP.DEERSL.VWGEDRNGTLLSVYYVPG.EMVRFYYHSGCVP-------fgdmsedd
U1RJ50_9ACTO/40-171                  ....KRQTIEEYKRNTLPRIEKFLTKLSLA.GA.GE.LVYEESDYDETC........GE-NKE....GKNYLSANIKGR.SIDVNKVIKYGNDILKPAGFSKRTERKY--D.NGDIVL.YWLNVKDGGYVSLTVSPQ.DFIGIFYVSGCRPTDGTT--tp......
U1QBB2_9ACTO/39-170                  ....KRQTIEAYKRDTVPMIEKFLVRISQA.GA.GE.FIFDGDDQDRRC........GE-NDN....GYDYWSPNISGK.PIEVAEVIKAGDKYLVPAGF--SKKTQRKHE.NGDVRF.FWMNKKDGGYVTAIVSPK.SHTGIYYISGCRPSDGSA--tp......
A0A1D8B0C7_9ACTO/31-164              rrap----IGVYLSDTEPLIERFVDALAKQ.NG.GA.LGYDGSAYFNGC.......gETGDEH....GIRVASPIFKVL.MTDAMDLRALSEQILEPAGF---TPPDTFAP.DEERSL.VWGEDRNGTLLSVYYVPG.EMVRFYYHSGCVP-------fgdmsedd
A0A1Q5PTB5_9ACTO/39-167              ....ERQPLEEFVSNVEPGIVEFMQSLDTA.GA.SVyLPRSNESELESC........GA-PIY....GYRLFGPMLFGK.AISEEKLLAIYEQQVKPLGF----DRQYRRAdEVNINY.EWFNLRDGGYVSVILRAN.GNLGARYASGCRP-------yrge....
A0A3P1SBI3_9ACTO/44-172              ....QRMTTEEFQREIEPKILRYVDEVALR.TA.SV.IQHDGDSKLDAC........--SEEG....SWVLHSQMFVTG.ILDAEELKQLGEEILVPLGF---TDITDSSE.GDLVAL.SWFNPLTGGYVGLGASDG.-STRFHYESSCLPTDGST--tq......
A0A7Z0VSI0_9ACTO/14-152              ....KRQTIESVQTEVLPAFKQLLDELSES.GA.GS.FSELKGPSLDGR........TTEKETgaivGFEVSTAVLAGN.AIPADSAREIGDRVLPPAGLSHFTDITPQDA.KSDTTF.NWHDEENGGFVELTILPK.GDLTIYYVSGNRPSDGST--tq......
E6KTE5_9ACTO/45-179                  ....EGQTTEVHIRDTLPRYLGIIEEVVVE.SG.GV.LGVSGKSRVDGC........ATKGTT....AMDIQWMVMVIP.AIDYEDLRRMVVEGAQRNGFAYSWDPVRRDK.LNSRTV.AVGDD-YGNSLIFYHHEAqDRIVISLYSGCMFPSHPLD-p.......
A0A1Q5PT75_9ACTO/40-168              ....ERQSLEEFISDIEPRFVEFMQTLDKEgAN.VY.LPRSAESELNSC........GY-PIF....GYRLFGPMIFGK.AIPEERLLEIYEQQVKPLGF----DRQYRQA.DEVNTNyEWFNTQDGGYVNVALFPD.GSLIATYASGCRP-------ygge....
E6KTE7_9ACTO/38-172                  ....EGQTTEVHIRDSLPRYLGIIEEVVVE.SG.GV.LGVSGKNRVDGC........LTKDTT....DMDIHWMMMVIP.AIDYEDLRRMVVEGAQRNGFAYSWDPVRRDR.LNSRTV.TVGDG-YGNSLSFYHHEAkDSIVISLYSGCMFPSQPLD-p.......
A0A1D8B427_9ACTO/47-183              ....QRESIEEYLRTVEPVMAAFVRALAEK.GG.GV.IGVDRRRYFNACt.....drGPGKEE....GWAFGTELLHIS.SLTDEDIEAAASQYLSVLPL-YKGTRGDVQK.DGSFVL.RSGDAANGGELQVNYFPD.DRSSMHYESRCRPSDGSMGD........
A0A1Q5PYE0_9ACTO/20-150              ....ERQSLAEFISEVEPGIVQFMQELDSA.GTkLW.LPKSNESSLESC........GY-PVY....GYKLRGPTLFGQ.AIPEADIAQLREHHIKPLGFVHT----YRRE.DEYGLIyKWFNPRDGGFVNVNLLPD.GRLVTSYVSGCRPYR-----gagk....
E6KQY7_9ACTO/14-143                  ....HLHSIEEFQRDVEPAIVAARNEFLTE.DT.I-.MGLFKNDYISEI........YPEEPP....LYTLLSRLYFFS.ETDADRLRDVYDAKLKPLGFTFSEKRTP---.--EMVLmLWTNADYSASVEVVTHLG.IRSGAHYGARNLRSDGSTDQ........
E6KTE6_9ACTO/41-172                  ....ERVSIEEYISRQLPEISSVAVPVAAE.TG.GE.LTVMGLPYVQVC........GSGDTQ....GYRVVGYTTVAP.SMSFERLEKLVTEN-KPDWAVAVQVDKQIDR.DATRGI.QLIDN-YGGLVEFKFSED.-SIAVRSRSACLPTNKPLDD........
E6KTE8_9ACTO/41-172                  ...d-RQPLETYVDEKLPEISRMAGQVAAE.TG.GE.LTVMGLPYVQAC........GIDNTQ....GYRVFGYSTVAP.QISFDRLEEAVRAH-RRDGVSGLWVQNDFRE.DGSRRI.YFTDN-DGNSAEFKYTET.-GIEMSSYSSCLPTSHALND........
A0A095YXX5_9ACTO/63-185              ....KRVSVEAFQRDVEPHILAARNEIYSG.SQ.SL.RPETEKSKISRL........YD----....GWELSSQRVRGG.TQSPDRVEEILGRYLEPLGY-VSIVHDQ---.---ESL.VWRDEKNGGRVEILIRDQ.-SLAFQYDTQDRPSDGSV--pd......
A0A1D8B428_9ACTO/47-182              ....QRESIEEYLRTVEPAMARFVRALAEK.EG.V-.IGVNGRRYFNACt.....drGPGKEE....GWAFGTERLFIS.SLTDRDVEAAASQYLSVLPL-YKGTRGDVQK.DGSFIL.RSGDAANGGELSVYYFPD.DRSSMRYESGCRPSDGSMGD........
A0A179B2Z7_9ACTO/19-152              ...d-RQTIEDYQRKTVPAIEEFMRRLLAD.GG.GQhYAAEGANELTLC........ET-KTD....GREYMSAVYETQvSVPPAKIRAIAKKTIEKAGLKIEQQDDE--R.DNVTGF.GWSDSKNGGFLILSAHPT.KGISFHFVSGCRPSATKID-d.......
A0A1Q5PVM4_9ACTO/20-148              ....ERQPLEEFISDVEPGVVKFMRALDSAgAN.LY.LSRGGESELKSC........GY-PVF....GYQIRGPMAFGK.AIAENTLLELYGQLVKPLGFDHTYRRAD---.EVNTTY.TWFNRRDGGYVTTVLFPD.GSLVVDYVSGCRP-------yhge....
A0A1Q5PUK8_9ACTO/39-169              ....ERQSLEEFISTVEPHIVEFMQTLDAEgAN.VY.LPRSAESYTESC........GY-PIF....GYRLKGPMLFGK.AVPEDKLLEIYEQQVKPLGFDRLYHSSD---.EVNTSY.KWFNTQDGGFVSVTLFPD.GDLVARYASGCRPYHG----agk.....
A0A095YXX5_9ACTO/229-361             ....KRQSIEVFEREVEPEILSFRDEIVGD.SS.YY.VA-RRPSEMETR........KRYPTP....EYWLESQRVQCG.PRDVGRVVEWGNAHLNPLGYELVYDYASPVP.GVGHYL.AWKDEKNGGLVTVILRQE.-NTEFSYKSGARPSDGSVS-d.......
A0A1Q5PTI2_9ACTO/39-167              ....ERQRLEEFISDIEPRLVEFMQSLDTAgAN.VY.LPRSNESELEPC........GA-PIY....GYRLFGPILFGK.AISEEKLLAIYEQQVKPLSFDYLYHSSD---.EVNTSY.KWFNAQDGGYVSITLFPN.GNLVARYASGCRP-------yrge....
A0A7Z1AIV5_9ACTO/99-238              ....QRATIEDVQRTILPAFQEILANLSAA.GA.GQ.FSELEGPSLTGRat....drNTGKIS....AFEVATAIAAGH.AIPPEEARRITGDIVTPLGMTQFSDLTPDDD.DTGEVSyNWFDPDNGGFVELTILPD.SSMTVYYISGMRPTDGST--tq......
#=GC seq_cons                        ....cRQolEpahc-lEPtIhcFhppLssp.uu.u..lshsspsplpuC........ss.spt....Gacltu.hhhsp.ulsscclcclspphlcPLGF.h.hcpss.pt.csspsl.tWhsspsGGhVplhhhss.tslshpYhSGCRPostsh..........
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