GenomeNet

Database: Pfam
Entry: DUF5373
LinkDB: DUF5373
Original site: DUF5373 
#=GF ID   DUF5373
#=GF AC   PF17343.1
#=GF DE   Family of unknown function (DUF5373)
#=GF AU   El-Gebali S
#=GF SE   PRODOM:PD035609
#=GF GA   28.70 28.70;
#=GF TC   35.20 32.00;
#=GF NC   25.40 24.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF CC   This family of unknown function is found in Caenorhabditis.
#=GF CC   Members of this family are predicted to contain 4 trans-membrane
#=GF CC   regions.
#=GF SQ   18
#=GS YLH9_CAEEL/3-177    AC P34363.1
#=GS YLH0_CAEEL/1-179    AC P34364.2
#=GS K7HNI3_CAEJA/1-50   AC K7HNI3.1
#=GS E3LSC5_CAERE/9-135  AC E3LSC5.1
#=GS H2VU77_CAEJA/1-105  AC H2VU77.2
#=GS B6IHL7_CAEBR/1-177  AC B6IHL7.1
#=GS G0MK62_CAEBE/4-179  AC G0MK62.1
#=GS G0MK60_CAEBE/1-154  AC G0MK60.1
#=GS G0MK59_CAEBE/1-184  AC G0MK59.1
#=GS A8XA93_CAEBR/1-186  AC A8XA93.1
#=GS E3LSC9_CAERE/1-175  AC E3LSC9.1
#=GS E3LSC4_CAERE/1-179  AC E3LSC4.1
#=GS A8XA96_CAEBR/1-151  AC A8XA96.1
#=GS G0MK63_CAEBE/1-184  AC G0MK63.1
#=GS YLH6_CAEEL/11-169   AC P34360.1
#=GS E3LSC6_CAERE/5-188  AC E3LSC6.1
#=GS YLH7_CAEEL/1-153    AC P34361.1
#=GS E3LSC8_CAERE/1-104  AC E3LSC8.1
YLH9_CAEEL/3-177               ......nnysidl-------------KQGPSLLYVIPI..KPVVLAVQLGAILFQFK.SIYD....FEYNFVGdLVFRTFVIFLSLTSFTAFLFNQKILMKAHLVMAIFLLA...GPIACLQYLVFDFYRAEFHGDnnlkwDHTSSFENYLIFILVILLAVALGSYTWLCHLLIEGLDEKN----.--------------------------apkrrpqckicsnhyvvpenekl........
YLH0_CAEEL/1-179               .............MSKFYDPSQPEQSYDSPKLFGIIPI..KFIVSFLQLVSIVSQIL.WLY-....SENDKIY.LVLLSVGIVLNVFTVVVFIKEHKLLMRAHYYSALIFTV...VPFI-YAVYTFISFIELFFGD.....-KDITFNQCSPFAYAFIFLCIYIFYLAMCRVLIKASEFQPDDMP.DLDTTQGLFHYNRDAYDGGERAKLMY...............................
K7HNI3_CAEJA/1-50              ............x-------------------------..-----------------.----....-------.--------------------------------------...---------------------.....---------------------LLFYIWMCYKLVKAVKRKTVHLP.EFDTTQGLYQFNRDAYDGVETVTLNY...............................
E3LSC5_CAERE/9-135             .........lakk--------------KGPMFFGVLPM..KSVILFMQFLAIFYQTYqFQDC...fGCFLSTV.YLIRIILIAVSFIGFIGYLLDRKTVMKVHLWTTIFVLA...IPVAIIQIGVFLY--------.....--------------------------------------------.--------------------------ctflyicwtissehvisledvlqksasemsl
H2VU77_CAEJA/1-105             ......mqvhfca-------------------------..-----------------.----....-------.-----------------------------ILFALVMTL...FGFGITGALYLYTLIKSK--D.....GRFGDDGELNRLIANFIILVSLLFYIWMCYKLVKAVKRKTVHLP.EFDTTQGLYQFNRDAYDGVETVTLNY...............................
B6IHL7_CAEBR/1-177             .............MAHFYEP-RDSRLSKAPLCCCCIPI..KFIVLLVQVLALVFQI-.WLLC...aEKTSNVM.LFVKVLLAVYTAFTFGVFLIEHKSLMNFHCFLGVICLL...APFA-HVALEYFASAKKLFLH.....YDYSPKTDV--FVIVGIIMLVVLVYLTMCRALVNELN-KQNQLPsYVAATQPSFNTEYMP-ELTEKTKLIH...............................
G0MK62_CAEBE/4-179             ............k-PKFQDLKQSQAIKEEPKFVAFLDNadKVFVLVLQAVLLGHLIYqYVVD....EVYASKE.WISSSIAIGFLAIIFIAFLFEKKSIIVAYSYSLALMAA...IPIGRIELLAADILKKLFNPDapvldGPNAMWNASIIIMWNLIILLALGLYLSVCFAVIDNIDLKKK---.--------------------------kksmtlphtvqnvil................
G0MK60_CAEBE/1-154             .............MSKFYET-HFSRSLDSPLLCGCFPI..KPIVLAAQLLMTIFFIH.DLVGt..aSSADTVS.IMGKVFMIIFLVSSFVAFLADYEVLMRLHHLVSCVVAL...IHIA-WFFMELFSFIKKVASE.....-TPINSSDVKVLLVPIGYSFVFVLYIWMCQQLIMVLG-------.--------------------------rkyilp.........................
G0MK59_CAEBE/1-184             .............MPSYYNPHHPN-VYESPKICCCIPI..KLIVLAIQAAALVFQVY.QICCgierSPSDKGA.LFLQFLAALYTGFTFVVFLINHRCLMCTHFCFGICLMM...IPLGFFVYYSFFVVLPGVLGL.....IDRVGANDIEQFFAAGFCILVLFSYIVMCKVLIDSLNHSP-LLP.EH------------------------iinqntqqpghiggghsegsqliy.......
A8XA93_CAEBR/1-186             .............MVKFYDPSQPEQYLSSPKLFGVLPI..KLIVISMQILYMLLQIV.WLTA...sGVTSKVS.ILLVIASVILTAFTVAVFVVENKSLMQAHIWVASLFLF...FPLAVFVLMIAQFFFDIKFLAt..ffGEGIYTHPITSLTVAAVFLCAYIAYLFLCHKLVEAKDQQPDDFP.ELDTTQGLFHYNRDAYDGSERVNLIY...............................
E3LSC9_CAERE/1-175             .............MPRFYDA---SSYSEPPKVC-CIPV..KLVVLFMQIAALILPIA.SICF...aRNQESHL.LFGQVLWAIYFGLSFVAFLVEHKGFMVLHCFFGIACWLgacVVIGLEYFKIRVFSDKPIFNG.....--QFFSNSI-LLVGTGILLFVALFYIIMCSALVRSLGR-EPVLP.DYNTAM---QQPTCPVDTSEHTKLIY...............................
E3LSC4_CAERE/1-179             .............MPKFYDPNQPEQYLKAPTLFGLFPI..KKVVTVMQIIWLSLQIA.FLSF....VDLAPLL.ILANIVSIVFCAFVIAVFIVENKILMRAHYWSALVFII...VVIGVLLFGTTSILLNVSAGN.....---FELKSLWYLIGGLIFFCALVIYASLCRKLIRALDQQPDNLP.DLDTTQGLFHFNRDACDGSERVNLIY...............................
A8XA96_CAEBR/1-151             .............MSNFYER-RVLHSMESPMLCDFIPV..KLVVLVVQIATLLITVG.VISR...nVSLSSES.AMFEIFVVVFLVASVVSFLADYELFMHIHYWVVCVLII...VPLY-YWGQSIVNLYNHIFNN.....---SESPAVFSFATSTFILCSYIFYIWSCRQLIISLG-------.--------------------------rkyvlp.........................
G0MK63_CAEBE/1-184             .............MVKFYDPNQPEQFLEVPKLCGVFPI..KVLVLAMQFIVMLFQIA.CLCV....FDSSKTI.IFFQITSIVLNAFTFAAFIVENKILIRTHYYAAAIFTI...VPIGFVLFSIILMFDVIFFGNr...lLTASPFESTFYLIAGILVLCAYIFYITMCRRLIKAFDRQPEDLP.ELDTTQGLFTFNRDAYDGAERVKLIY...............................
YLH6_CAEEL/11-169              ...ekskatisfw-------------------------..KFIAMFIQALFLIGLVEdLCYY...hMFYSRQY.FFLEILVTIHTGFSFIVFLIEHKPLIMLHVGYMTLLTI...IPIA-YMVMQGVEFGILIFDD.....YHILVFRDFHKFGCSIMFSLYYIGYIVVCFLFIEALEKKP-VLP.QVYSI---------------------kpklvaavnpsnn..................
E3LSC6_CAERE/5-188             tkfndsksapnvv-----------QKKKEPMLLG-LSV..KHLILLYHVVFFLVQIDsFIHI....KDKKFND.IVWGIITVICISGSFYGILTENKKYIKFHYWYCIFVSA...IPVAFLQLLSVGIIHRLVTGEe..gfLSGEIMCALKAFGYVLGFVMIFFLYIWMCYKLHKHLANHSMVLPySAKDVHVIYNPNYDAN----------hhsins.........................
YLH7_CAEEL/1-153               .......mthfet--------RPLCSLNSPLLCGFFPI..KLAVLLVQLIAIVIQFC.MLYY...nGNQEEIV.FVAMVLLLVFTISSFVAFLGEYGTMMAIHYYVSCILLI...WPAVVF-IMKLISLCNKLFIE.....-ENATSRDAKDFMKITAILFAVIFYIWMCLQLIRVA--------.--------------------------ksrlilpr.......................
E3LSC8_CAERE/1-104             .............MSNFYQT-RVIHSVESPMFFDRFPI..KLLVIVVQVVTLLLNIG.YMSQ....PSLERGV.FIFEMCINLFLVASIVAFLADYELLMHIHYWAVCVGTI...IPLIFW---------------.....--------------------------------------------.--------------------------glavkdlf.......................
#=GC seq_cons                  ..............spa.p..p..p.hcuPhlhshhPl..KhlVLhhQllhllhplh.hlhh.....shsphh.hhhplhhllhhshoFssFLh-pKhlMphHhahuhlhhl...lPluhhhhh.hhhhhphhhsp......p....psh..hhhshhhhhshlhYlhhChtLlculs.p...hP..h.......................................................
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