GenomeNet

Database: Pfam
Entry: DUF556
LinkDB: DUF556
Original site: DUF556 
#=GF ID   DUF556
#=GF AC   PF04476.11
#=GF DE   Putative methanogenic enzyme for methanofuran
#=GF AU   Waterfield DI, Finn RD
#=GF SE   COG1891
#=GF GA   21.20 21.20;
#=GF TC   21.20 30.80;
#=GF NC   21.00 20.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   25372812
#=GF RT   Structure of the methanofuran/methanopterin-biosynthetic enzyme
#=GF RT   MJ1099 from Methanocaldococcus jannaschii.
#=GF RA   Bobik TA, Morales EJ, Shin A, Cascio D, Sawaya MR, Arbing M,
#=GF RA   Yeates TO, Rasche ME;
#=GF RL   Acta Crystallogr F Struct Biol Commun. 2014;70:1472-1479.
#=GF DR   INTERPRO; IPR007565;
#=GF CC   This family has a classical TIM-barrel structure whose
#=GF CC   biological unit is a homohexamer. The conserved, potentail
#=GF CC   active-site residues suggest an enzymic function in the
#=GF CC   production of methanofuran [1].
#=GF SQ   142
#=GS D5VS81_METIM/3-231       AC D5VS81.1
#=GS A0A0M9X680_9ACTN/4-234   AC A0A0M9X680.1
#=GS E8TE86_MESCW/4-219       AC E8TE86.1
#=GS A2SJ33_METPP/3-215       AC A2SJ33.1
#=GS E1RDR9_METP4/3-224       AC E1RDR9.1
#=GS G3J251_9GAMM/4-220       AC G3J251.1
#=GS Q2NH72_METST/3-230       AC Q2NH72.1
#=GS N6Y107_9RHOO/3-226       AC N6Y107.1
#=GS F5SZ22_9GAMM/7-224       AC F5SZ22.1
#=GS D7A5G8_STAND/8-231       AC D7A5G8.1
#=GS A3CVU8_METMJ/3-225       AC A3CVU8.1
#=GS Q1YFW6_AURMS/4-218       AC Q1YFW6.1
#=GS J7QR92_METSZ/13-227      AC J7QR92.1
#=GS Q13QV4_BURXL/4-220       AC Q13QV4.1
#=GS G7WLA7_METH6/3-229       AC G7WLA7.1
#=GS B2JVM6_BURP8/4-224       AC B2JVM6.1
#=GS D5WEG8_BURSC/4-220       AC D5WEG8.1
#=GS L0KWV3_METHD/3-229       AC L0KWV3.1
#=GS MFNB_METJA/3-231         AC Q58499.1
#=GS MFNB_METJA/3-231         DR PDB; 4U9P A; 3-231;
#=GS MFNB_METJA/3-231         DR PDB; 4RC1 B; 3-231;
#=GS MFNB_METJA/3-231         DR PDB; 4RC1 H; 3-231;
#=GS MFNB_METJA/3-231         DR PDB; 4RC1 E; 3-231;
#=GS MFNB_METJA/3-231         DR PDB; 4RC1 A; 3-231;
#=GS MFNB_METJA/3-231         DR PDB; 4RC1 F; 3-231;
#=GS MFNB_METJA/3-231         DR PDB; 4RC1 I; 3-231;
#=GS MFNB_METJA/3-231         DR PDB; 4RC1 D; 3-231;
#=GS MFNB_METJA/3-231         DR PDB; 4U9P B; 3-231;
#=GS MFNB_METJA/3-231         DR PDB; 4RC1 C; 3-231;
#=GS MFNB_METJA/3-231         DR PDB; 4U9P C; 3-231;
#=GS MFNB_METJA/3-231         DR PDB; 4RC1 G; 3-231;
#=GS A0A0A7GJ40_9EURY/3-230   AC A0A0A7GJ40.1
#=GS D5SUM2_PLAL2/19-268      AC D5SUM2.1
#=GS B2IG59_BEII9/88-209      AC B2IG59.1
#=GS Q0FYG4_9RHIZ/4-218       AC Q0FYG4.1
#=GS F0TC78_METLA/3-231       AC F0TC78.1
#=GS H5WKE9_9BURK/3-225       AC H5WKE9.1
#=GS E8R4Z5_ISOPI/10-240      AC E8R4Z5.1
#=GS A0A0E3L0A8_9EURY/3-229   AC A0A0E3L0A8.1
#=GS D7C297_STRBB/2-232       AC D7C297.1
#=GS A3ZQH6_9PLAN/4-223       AC A3ZQH6.1
#=GS D5MKC5_9BACT/3-229       AC D5MKC5.1
#=GS B8GDK9_METPE/3-224       AC B8GDK9.1
#=GS F0SRJ3_RUBBR/4-245       AC F0SRJ3.1
#=GS A0A0H4CIM5_9ACTN/3-233   AC A0A0H4CIM5.1
#=GS Q2FS88_METHJ/3-224       AC Q2FS88.1
#=GS C5CPV3_VARPS/5-221       AC C5CPV3.1
#=GS D7DS38_METV3/3-231       AC D7DS38.1
#=GS A2ST93_METLZ/3-225       AC A2ST93.1
#=GS Y6440_STRCO/3-233        AC Q9ZBH3.1
#=GS MFNB_METMP/3-231         AC Q6LZC1.1
#=GS H8GQZ3_METAL/4-220       AC H8GQZ3.1
#=GS MFNB_METKA/5-233         AC Q8TUZ9.1
#=GS G7ZAY4_AZOL4/4-220       AC G7ZAY4.1
#=GS N0BEP7_9EURY/4-231       AC N0BEP7.1
#=GS E8W242_STRFA/3-233       AC E8W242.1
#=GS V6JRN2_STRNV/3-233       AC V6JRN2.1
#=GS F3NDC8_9ACTN/3-233       AC F3NDC8.1
#=GS A0A0F7JUH0_9GAMM/4-218   AC A0A0F7JUH0.1
#=GS I1XFK9_METNJ/1-157       AC I1XFK9.1
#=GS Q12VF6_METBU/3-227       AC Q12VF6.1
#=GS A0A0A8K339_9RHIZ/4-219   AC A0A0A8K339.1
#=GS C7PZG9_CATAD/3-233       AC C7PZG9.1
#=GS G4T028_META2/21-237      AC G4T028.1
#=GS H2JMK4_STRHJ/3-233       AC H2JMK4.1
#=GS A0A0M2U0R3_9FIRM/3-231   AC A0A0M2U0R3.1
#=GS N0B6U5_9RHIZ/12-227      AC N0B6U5.1
#=GS D5E8I4_METMS/3-229       AC D5E8I4.1
#=GS D3S2M0_FERPA/3-230       AC D3S2M0.1
#=GS C6XEF2_METGS/4-218       AC C6XEF2.1
#=GS B2JX52_BURP8/4-220       AC B2JX52.1
#=GS A0A0M2GBH5_9ACTN/3-233   AC A0A0M2GBH5.1
#=GS A0A0E3S508_9EURY/5-231   AC A0A0E3S508.1
#=GS Q3JF34_NITOC/4-221       AC Q3JF34.1
#=GS A0A0C1TN64_9ACTN/11-177  AC A0A0C1TN64.1
#=GS I4BX62_ANAMD/10-237      AC I4BX62.1
#=GS D5C442_NITHN/4-220       AC D5C442.1
#=GS D6KD14_9ACTN/2-232       AC D6KD14.1
#=GS D2QXD0_PIRSD/4-224       AC D2QXD0.1
#=GS A7I923_METB6/3-224       AC A7I923.1
#=GS A7IMS7_XANP2/15-237      AC A7IMS7.1
#=GS I0HWI2_RUBGI/4-220       AC I0HWI2.1
#=GS G7ZBV6_AZOL4/4-224       AC G7ZBV6.1
#=GS A0A0B5IP84_9ACTN/3-233   AC A0A0B5IP84.1
#=GS L0DCN6_SINAD/4-221       AC L0DCN6.1
#=GS Q1H0Z0_METFK/4-220       AC Q1H0Z0.1
#=GS A0A0F7FYD5_9ACTN/10-240  AC A0A0F7FYD5.1
#=GS K4MDK2_9EURY/3-229       AC K4MDK2.1
#=GS MFNB_METTH/3-230         AC O26244.1
#=GS MFNB_METAC/3-229         AC Q8THS6.1
#=GS B8EKF6_METSB/4-219       AC B8EKF6.1
#=GS U6ECS5_9EURY/3-231       AC U6ECS5.1
#=GS D9XMZ4_9ACTN/3-233       AC D9XMZ4.1
#=GS A0A0J6RJ87_9RHIZ/11-219  AC A0A0J6RJ87.1
#=GS L0HGW6_METFS/3-224       AC L0HGW6.1
#=GS D7DPW6_METV0/15-236      AC D7DPW6.1
#=GS E1TEU8_BURSG/4-220       AC E1TEU8.1
#=GS A6C4I0_9PLAN/8-236       AC A6C4I0.1
#=GS H0HRB7_9RHIZ/4-219       AC H0HRB7.1
#=GS C6WV59_METML/4-225       AC C6WV59.1
#=GS F5R8I0_METUF/1-224       AC F5R8I0.1
#=GS F7XPD0_METZD/3-229       AC F7XPD0.1
#=GS MFNB_METS3/3-231         AC A5UNQ5.1
#=GS A0A0D6JAY0_9RHIZ/17-235  AC A0A0D6JAY0.1
#=GS A0A0B4XC79_9RHIZ/4-219   AC A0A0B4XC79.1
#=GS B1M296_METRJ/14-222      AC B1M296.1
#=GS J0RZ50_9EURY/3-224       AC J0RZ50.1
#=GS B0UG99_METS4/15-221      AC B0UG99.1
#=GS C5B154_METEA/14-224      AC C5B154.1
#=GS MFNB_META3/3-231         AC A6UU96.1
#=GS H1YWT1_9EURY/3-224       AC H1YWT1.1
#=GS D7E7G6_METEZ/3-229       AC D7E7G6.1
#=GS G8MDQ4_9BURK/4-222       AC G8MDQ4.1
#=GS A0A0F3IJ22_9GAMM/4-218   AC A0A0F3IJ22.1
#=GS R9SKK3_9EURY/3-231       AC R9SKK3.1
#=GS A0A0F8Y2K1_9ARCH/7-238   AC A0A0F8Y2K1.1
#=GS A0A0F2SC28_9FIRM/16-244  AC A0A0F2SC28.1
#=GS Q0BU42_GRABC/4-225       AC Q0BU42.1
#=GS E4RM66_HALHG/3-230       AC E4RM66.1
#=GS F6D669_METPW/3-231       AC F6D669.1
#=GS G2DX21_9GAMM/4-219       AC G2DX21.1
#=GS Y6403_STRGG/3-233        AC B1W5S5.1
#=GS MFNB_METBF/3-229         AC Q46DH3.1
#=GS MFNB_ARCFU/3-230         AC O28087.1
#=GS A0A0M0BYB2_9ARCH/3-231   AC A0A0M0BYB2.1
#=GS A0A0F7N1Y6_9ACTN/3-233   AC A0A0F7N1Y6.1
#=GS I1YJP7_METFJ/7-224       AC I1YJP7.1
#=GS A0A0E3X1A5_METMT/3-227   AC A0A0E3X1A5.1
#=GS F2KQ15_ARCVS/3-228       AC F2KQ15.1
#=GS I3CHH0_9GAMM/4-220       AC I3CHH0.1
#=GS D1Z2Y8_METPS/3-227       AC D1Z2Y8.1
#=GS MFNB_METMA/3-229         AC Q8PXV2.1
#=GS B1Y0Y4_LEPCP/23-247      AC B1Y0Y4.1
#=GS H0Q584_9RHOO/4-228       AC H0Q584.1
#=GS G0A6W1_METMM/4-219       AC G0A6W1.1
#=GS G8XHM5_STREN/8-238       AC G8XHM5.1
#=GS Q7URG4_RHOBA/32-257      AC Q7URG4.1
#=GS A0A0F7IEG2_9EURY/3-230   AC A0A0F7IEG2.1
#=GS C0N597_9GAMM/4-220       AC C0N597.1
#=GS A0B617_METTP/5-231       AC A0B617.1
#=GS F8J8T1_HYPSM/12-227      AC F8J8T1.1
#=GS Q7NR24_CHRVO/3-231       AC Q7NR24.1
#=GS B8ILG5_METNO/17-225      AC B8ILG5.1
#=GS G8AVE2_AZOBR/4-224       AC G8AVE2.1
#=GS Q0W6B9_METAR/3-227       AC Q0W6B9.1
#=GS A0A0K8P5D4_9BURK/31-254  AC A0A0K8P5D4.1
#=GS F4BY02_METCG/3-229       AC F4BY02.1
#=GS I9W7D2_9RALS/4-220       AC I9W7D2.1
#=GS G2P3P4_STRVO/10-240      AC G2P3P4.1
#=GS B9TAC8_RICCO/1-217       AC B9TAC8.1
#=GS D3E3E8_METRM/3-231       AC D3E3E8.1
#=GS A0A059VV05_STRA9/10-240  AC A0A059VV05.1
#=GS E3GXG6_METFV/3-231       AC E3GXG6.1
#=GS Q609J1_METCA/4-220       AC Q609J1.1
D5VS81_METIM/3-231                  ...............................LLVSPIDVEEAKEAI..EG..GADIIDVKNPKEGSLGANFPWVIREVRK........ITPK....................S...LLVSATVGDVPYKP.................GTVSLAALGAGMS.G.....ADYIKVGLYG.....VKNYNQAVELMKSVVKAVK.DFD....DNK.IVVAAGYADAYR..VGAVDPLV.IPKIARDS......G.ADVAMLDTAIKD.GKT....LFDFLSKEILEEFVSEVHDYGLKCALAGTIKKDHIPILKEI..GTDIVGVRGAACKGG.DRNkGRIDRNLVREL-k.................
#=GR D5VS81_METIM/3-231       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0M9X680_9ACTN/4-234              ...............................LLISPDGVEEALDCA..KSaeHLDIVDVKKPDEGSLGANFPWVIREIRD........AVPA....................D...KPVSATVGDVPYKP.................GTVAQAALGAVVS.G.....ATYIKVGLYG.....CTTPEQGVEVMSAVVRAVK.DHR....PKA.LVVASGYADAHR..IGCVNPLA.VPHIAARS......G.ADAAMLDTAVKD.GTR....LFDHVPPDVCAEFVRLAHAAGLLAALAGSVQQTDLGPLTRI..GTDIVGVRGAVCAGG.DRKaGRIQPRLVAAF-r.................
#=GR A0A0M9X680_9ACTN/4-234   pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
E8TE86_MESCW/4-219                  ...............................MLASVTGIEEAEIAL..SG..GVDIVDLKDPKAGALGAVSMETMLRTIS........FIAG....................R...APVSAVCGDLPMEP.................ETIRIKAEEIAAT.G.....VDYVKIGFFP.....SANISACAQALEPLAART-.---....---.KLIAVLFADLA-..----PDFE.LLPMFARH......R.FHGVMVDTAQKG.KGR....LLDHLPPERIPGFVDRTKSLGLMVGLSGSLEAPDIPRLLPF..APDFLGFRGALCGHS.GRT.SSISAEAVSQI-r.................
#=GR E8TE86_MESCW/4-219       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A2SJ33_METPP/3-215                  ...............................LLVSVRDVDEALAAA..AA..GVDFIDLKEPSAGALGALPPATLEAIVAa.....lqHAPG....................R...RPISATIGDCAGTT.................E-VLERVAETAAC.G.....VDYVKVGIAR.....--GQHALLDALAMC----G.H--....---.AVVPVFVADHG-..----IDGA.LLARAGAL......A.FPALMLDTEDKA.RGS....LFDIASEVQLQRFVTQVRRSGKLCGLAGALRFEHLARLQSI..APDFAGFRSAVC-SG.ART.AALDVQRVRAL-r.................
#=GR A2SJ33_METPP/3-215       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
E1RDR9_METP4/3-224                  ...............................LLVSPSSVEEAKLSL..A-..-ADIIDVKKPSEGSLGANFPWVISAIKD........LTNK....................-...-PVSAAIGDYEYRP.................GGAAQGAFGAASA.G.....ADYIKIGLM-.....LKDESEAFEMIESVNKAVK.WKY....PEK.TVVIAAYADFER..IDTISPMD.ITKLVAKA......G.ADVAMIDTAVKD.GKR....LFDFLDEKTLTEFTEANRKLGLKTALAGSLKFEDLDVLKRI..NPEIIGVRGMVC-GG.DRS.AVIREELVQK--ai................
#=GR E1RDR9_METP4/3-224       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
G3J251_9GAMM/4-220                  ...............................MLASVNSVEEALQAL..SA..NVDIVDLKQPALGALGALETDLVKNIVN........AIGG....................R...CPVSATVGDLPMQP.................EIVYQAVKAMAET.G.....VDYIKIGFFP.....GGDWQGTLEKLAALTQQNL.---....---.ALIAVLFADTQ-..----PDFA.VIDSLKNV......G.FKGVMLDTMNKK.NGS....LTQVMTKVDIAQFVRLAKDRSMLCGLAGSLRLDDIAELMPY..QPNYLGFRGALCLDH.NRT.AQLNRSSIMQI-k.................
#=GR G3J251_9GAMM/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
Q2NH72_METST/3-230                  ...............................LLVSAINLDEAKEAL..AG..GADILDVKNPKEGSLGANFPWIIKEISD........YAED....................-...VIVSTTIGDVPYKP.................GTVSLAALGSAVS.G.....SNYVKVGLYG.....PENYEQAVEVMNAVVKTIN.NYD....ENI.TVVACGYADAYR..VGSVEPID.IPKVAFDS......G.CDLAMLDTYLKD.GRR....LTDHMTYDELKSFVETSHNYNLKVALAGSVNASDIPLLEDI..NCDIMGVRGCVCTGG.DRNnGTIDSLLVRQL-k.................
#=GR Q2NH72_METST/3-230       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
N6Y107_9RHOO/3-226                  ...............................MLVSVRDVAEAREAL..QA..GVDFVDLKEPSAGALGGLALPLIRELVA........ALRAgegg...........ldaraR...PLISATIGDLPVAA................rADILARARAVGAC.G.....VDLVKVGVPG.....--RGEAACGLLAA-LATLP.L--....---.AIVPVLIADDG-..----LDAA.VIDAACVP......P.FAAVMADTQVKH.AGS....LLDLLGAEALGAFIDRAHGAGRMVGLAGALRAADLAPLARL..GPDFAGFRSAVC-EG.RRE.GRLDPRRLRAL-r.................
#=GR N6Y107_9RHOO/3-226       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
F5SZ22_9GAMM/7-224                  ..............................w-LASVQSLEEAQSLN..EC..LPDILDMKQPAQGALGALPLDVVKNVVK........WASG....................R...CLTSATVGDLPMQV.................QFIEPAIMKMAET.G.....VDYVKVGLFG.....GDEQAECLQELTPVIKQLN.T--....---.PVIAVTFADRH-..----YEKD.VIKQVLQT......G.FSGVMIDTAEKN.GRS....LLDLWSVDALTDFVNVVKDAQQLCGLAGALRIDDIATLRTL..QPDYLGFRSALCPDR.KRN.GTLSVTLAK---tia...............
#=GR F5SZ22_9GAMM/7-224       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D7A5G8_STAND/8-231                  ...............................LLASVADLHEMELAR..AG..GADIVDLKQPAFGALGAWSQDALTAAVM........LWNAwgvq...........lgehtR...PALSATAGDQPMVP.................ALIRAAAERVAEA.G.....VPIVKVGLFA.....SKHTNECIEALAPLAGRA-.---....---.RVIGVLFADEA-..----PDFG.ILAALGRA......G.FAGVMIDTADKK.AGP....LTAHLDPLTLGQFVAEARRHGLITGLAGSLRLEDIPALIGV..GADYLGFRGALC-EG.GRT.GTLDPMRLGQ--vy................
#=GR D7A5G8_STAND/8-231       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A3CVU8_METMJ/3-225                  ...............................LLVSPSSIEEAKSSL..S-..-ADIIDVKKPSEGSLGANFPWIIRGIKE........IAGK....................-...KPVSAAIGDNEYKP.................GTAALSAYGAAHA.G.....ADYIKVGLM-.....FDGEDRAREVIEAVTTAVK.HEF....PEK.YVVIAAYADFAR..MGTISPLA.IGSLVADA......G.ADVAMIDTGIKD.GKS....LFEFMDEETLIRFVGQNQDLGLQTALAGSLKFEDLDALKRI..NPEIIGVRGMVC-GG.DRS.TTVRAELVEKA-m.................
#=GR A3CVU8_METMJ/3-225       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
Q1YFW6_AURMS/4-218                  ...............................LLASVTGPHEAGIVL..EG..GADLVDLKDPAKGALGAVSPQVLAETMD........MVGG....................R...RPVSAVAGDLPVLP.................DVVREAVE--ARV.A.....ADFVKIGLFP.....-ASRDARLAVIEA-LRPL-.--A....NRT.GLIAVFFADGD-..----PDFS.LLPVLAEA......G.FRGAMIDTIGKS.SGR....LMAHLSMTALGDFVRHARDLGLMSGLAGSLEPPDVPRLAVL..RPDYLGFRGALT-TG.ARD.APVDIAAVRTI-r.................
#=GR Q1YFW6_AURMS/4-218       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
J7QR92_METSZ/13-227                 ...............................MLASVLSRDEAEIAL..AR..GADIIDCKAPSRGALGALPLDTVAEIVA........FVDG....................R...RPVSAVV-ELPHDV.................AHARRDFEEVVAA.G.....VDYVKFALPA.....TPDAVEIIEALAPLTART-.---....---.KLVAVLFADLG-..----PEFD.TLEPLAGA......G.FHGAMLDTAHKG.KGR....LVDFMSVGALSEFVARCRELGLASGLAGALESPDVPRLLVT..GADVLGFRGALCAHG.ERR.AAIDARA-----tmlir.............
#=GR J7QR92_METSZ/13-227      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
Q13QV4_BURXL/4-220                  ...............................LLASVRSDEEAFDAA..QA..GAELIDLKEPNAGALGGLSIGDITQIAR........RLRA....................HypvKPISATIGDVPADA................lDEITTRVIEVSDA.G.....IDYVKVGVTP.....GPAARRCLEQLANLPA---.---....---.AVVPVLLCDGG-..----MDGE.LVAYAATL......D.FVGVMFDTAGKD.GST....LFDHVDSDTLAQWLRITRERGAMSGIAGSLGWAQFEQIRAL..APDVAGFRTALCV-D.GRR.SRLDPQRVAQW-a.................
#=GR Q13QV4_BURXL/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
G7WLA7_METH6/3-229                  ...............................LLVSPINAVEAEAAM..AG..GADILDVKNPREGSLGANFPWVIRSVAE........VAAG....................R...VPVSATIGDFDFKP.................GTASLAALGAAFS.G.....ADYIKVGLLK.....IRDRDEAAEMLRPLVRSVK.EFD....ANK.RLVAAAYSDASR..VGSISPMD.LPEVAAEC......G.ADVVMVDTAIKD.GRT....TFEFMTESEISDFIALGHDLGMEVAIAGTIKFGDLALLKRV..GPEIIGVRGAVC-GG.DRA.GEIKEELVRRM-k.................
#=GR G7WLA7_METH6/3-229       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
B2JVM6_BURP8/4-224                  ...............................MLASVRNLDEARDAA..RA..GADLIDLKEPGAGALGAVSAPRIAHIVQ........SLRAg.................fpH...LPISAAIGDLQPGD................dAGLEFRAAQAGRC.G.....VDYVKAGVPA....dGGSFDVACRTLAS-MREL-.---....-QW.NMVPVLLVDNG-..----LDLR.IVDYASEL......R.FAAVMVDTATKK.RGN....LFQCVPLAVLDRVVQIARSHNVMAGLAGSLLSGHVPLIRAL..GPDIAGFRTALC-DG.SRT.GRLNAARVHDL-r.................
#=GR B2JVM6_BURP8/4-224       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D5WEG8_BURSC/4-220                  ...............................LLASVRSDEEAFDAA..RA..GAELIDLKEPDDGALGGLSIGAITNIAR........QLRA....................RypvKPISAAIGDVPADA................fDEIAARVIDVSDA.G.....VDYVKVGVAR.....GPAARRCIEQLANLPA---.---....---.TVVPVLLCDGG-..----MDDE.LVSHTAAL......G.FAGLMFDTASKD.GGT....LFDHVDVDSLARWLRLARQRGAMVGIAGALGWAQLPQIRAL..APDVAGFRTALC-AD.GRR.SRLDPERVAQW-a.................
#=GR D5WEG8_BURSC/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
L0KWV3_METHD/3-229                  ...............................LLVSPINKEEAIAAH..NG..GADIIDVKNPKEGSLGANFPWVIRSVKE........AIGS....................E...KPISATIGDFNYKP.................GTASLAALGAAAA.G.....AQYVKVGLFD.....VRTEDQALEMLTNINRAVK.DYD....PSK.KVVASGYSDYKR..INSISPFL.LPAIGAKA......G.VDVVMVDTGIKD.GRS....TFEFMSEEELMRFTGSIRDVGLESALAGTLKFEDLPVLRRI..RPDIIGIRGMVC-GG.DRT.ACIQQELVEKLK..................
#=GR L0KWV3_METHD/3-229       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
MFNB_METJA/3-231                    ...............................LLVSPIDVEEAKEAI..AG..GADIIDVKNPKEGSLGANFPWMIKAIRE........VTPK....................D...LLVSATVGDVPYKP.................GTISLAAVGAAIS.G.....ADYIKVGLYG.....VKNYYQAVELMKNVVRAVK.DID....ENK.IVVAAGYADAYR..VGAVEPLI.VPKIARDA......G.CDVAMLDTAIKD.GKT....LFDFQSKEILAEFVDEAHSYGLKCALAGSIKKEHIPILKEI..GTDIVGVRGAACKGG.DRNnGRIDRELVKELK..................
#=GR MFNB_METJA/3-231         SS    ...............................EEE--SSHHHHHHHH..HH..T-SEEEE--GGG-TT----HHHHHHHHH........HS-T....................T...SEEEEEEEEE-S-H.................HHHHHHHHHHHHT.T.....-SEEEEEE-S.....--SHHHHHHHHHHHHHHHH.HH-....TTS.EEEEEEETTGGG..TT---GGG.HHHHHHHH......T.-SEEEEE-SS-S.S--....HHHHS-HHHHHHHHHHHHHTT-EEEE-SS--GGGHHHHHHT..T-SEEEESGGGBTTS.STTTSSB-HHHHHHHH..................
#=GR MFNB_METJA/3-231         AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0A7GJ40_9EURY/3-230              ...............................VLVSPMNLEEALESL..KG..GADIIDVKNPAEGSLGANFPWVIRSVKG........LVEE....................H..gKLLSATVGDLDFKP.................GTASLAALGAAVA.G.....ADYIKVGLYG.....VRSSEQVYEMMEKVVKAVK.DYN....PSA.YVVAAAYADHSR..VGSVSPLA.IAEPASNA......G.CDGIMVDTAIKD.GKN....LFEFMTREDLEKFIDSARDGGMFCALAGTLSWEHIDILKDL..RPDIIGVRTMVC-ES.GRN.SKIKSELVSKL-m.................
#=GR A0A0A7GJ40_9EURY/3-230   AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D5SUM2_PLAL2/19-268                 ...............................LLVSVRNAEEARLVV..NS..GVAVLDVKDPARGALGRADESVWREILA........VAGKhrvapgvsekssgrptrvhsG...LVTSLALGELLEVE.................-------PCAIPE.G.....VDVLKVGLAQcgrqqCAGQREDQEGWTRKWLQFR.EQTealsKRSfRWMAVAYFDSA-..-ARAPDLEeVKTFAIQQ......Q.LAGVLIDSYEKT.GQT....MTDVYSWEQLSACRDELVAAGMLLAIAGQIREEMLPVLKKL..EPHLLAVRSAVCQLR.DRN.RSVSPEALEKF-s.................
#=GR D5SUM2_PLAL2/19-268      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
B2IG59_BEII9/88-209                 wcaglashvpdarifavflsehgwrpddlag---------------..--..----------------------------........----....................-...--------------.................-------------.-.....----------.....-------------------.---....---.------------..--------.---L-VAE......N.FAGAMLDSAEPN.RAH....LLKHDGIVALHEFVQACQAAGLSAGFAGALETPDIARLLVL..EPSFLSFRGALRREH.RRQ.GVLDPEALA---lvr...............
Q0FYG4_9RHIZ/4-218                  ..............................f-LASVSDPDEALAAL..RG..GADIIDLKNPADGALGGVSPELIARTIA........TVGG....................R...RPVSAVAGNLPMEP.................DVVRKAV--EARL.E.....ADFVKIGLFP.....-----ASPEATQSVIEAAA.EFG....EKS.LMIAVLFGDQA-..----PDFD.ILDKLAAC......G.FSGVMLDTMEKG.AGG....LTRHLSPAQLRDFVGRAKTRNLMVGLAGSLEGPDIPRLAPL..EPDFLGFRGALT-QG.GRN.ALIEESRVREI-a.................
#=GR Q0FYG4_9RHIZ/4-218       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
F0TC78_METLA/3-231                  ...............................LLISPINAEEALESI..EG..GADIVDVKNPKEGSLGANFPWVIKNIRE........ITPE....................G...MHVSATLGDVPYKP.................GTVSLAAAGAVVS.G.....ADYIKVGLYG.....TKNYDEALEVMENVVKSVR.EFD....EDA.LVVASGYADAHR..VGAVDPME.IPRVAADA......G.ADLAMVDTAVKD.GKT....LFDFMDVEKLQKFNDSIHDYGLKSALAGSVKKDQLKLLYDI..GCDVVGIRGAACTGG.DRNnGSIHRTAVKEL-k.................
#=GR F0TC78_METLA/3-231       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
H5WKE9_9BURK/3-225                  ...............................LLVSVRNVTEAREVA..AT..GVDFIDLKDPADGALGGLPVATISEVVLa.....lrAQPG....................S...GRISATIGDHASDA................lDAILQRVAAVAAT.G.....VNYVKVGISP.....GPGVTALLEALAR----CG.A--....---.TVVPVFIADAG-..---VPMAA.VRAALAVAgd.dfhV.FPALMLDTQAKL.GGS....LLQRVPVSALAEFIEAVQASGRLAGLAGALRLIELETLRRL..APDFAGFRSAVC-DG.DRA.GNLVPQRVRAL-c.................
#=GR H5WKE9_9BURK/3-225       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
E8R4Z5_ISOPI/10-240                 ...............................LLVSVASATEAVEAL..QG..GADLIDLKRPDRGPLGRPDASDVLDLAR........ILPD....................P...HQRSLALGELADGP.................PDLHWVA-HLGEA.R.....PRFVKFGTSR.....CRASDDQTPSFSWRERARAwVES....HDW.QVILGIYADFDQpgVNGLEPTR.AVEEAHAL......G.CAGLLVDTFDKA.NPT...rWYRQPAPPITPDWVAHARASGLLVALAGSLDAQAIPRLATW..QPDFIAVRSAACLHG.DRR.GPIDPRRVEHL-r.................
#=GR E8R4Z5_ISOPI/10-240      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0E3L0A8_9EURY/3-229              ...............................LLVSPINREEAIITS..KS..GADIIDIKNPKEGSLGANFPWVVRDVKE........AVNG....................E...QPISAAIGDFNFKP.................GTAALTALGAAVA.G.....ADYIKIGLYD.....IQTEEQALELLTGVVKAVK.DYD....PRK.RVVASGYSDYER..INSISPML.LPAVAAEA......G.ADVVMVDTGVKD.GKS....TFEFMDEEKLTEFVGLGHENGLQVAIAGSLKFEDLSLLEAI..GPDIIGVRGMVC-GG.DRS.NAIKQDLVEKL-v.................
#=GR A0A0E3L0A8_9EURY/3-229   AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D7C297_STRBB/2-232                  ...............................LLISPDSVEEALDCA..KAaeHLDIVDVKKPDEGSLGANFPWVIREIRD........AVPA....................D...KPVSATVGDVPYKP.................GTVAQAALGAVVS.G.....ATYIKVGLYG.....CTTPEQAIAVMRGVVRAVK.DYR....PDA.FVVASGYADASR..IGCVNPLA.LPDIARRS......G.SDAAMLDTAIKD.GTR....LFDHVPPDVCAEFVRLAHEADLLAALAGSVKVADLGALTRI..GTDIVGVRGAVCQGG.DRNtGRIQPQLVAAF-r.................
#=GR D7C297_STRBB/2-232       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A3ZQH6_9PLAN/4-223                  ...............................LLVSVRSAIEAEAAL..SG..GADWIDIKEPTRGSLGAAEPHVWREIVQ........TVEQ....................R...APVSIALGEISDGA.................GAWGPDTFR----.G.....ASMVKYGLAK.....LSDCTDWMSIASTAYDRVP.D--....-SC.SRVAVYYADEER..A-RCPPLAdVVQWSKRI......S.ASAILIDTFVKD.GRT....LFDFLSIDQLAAATQQIRAIGAIAACGGSLTKLHFAAAIVA..GADVLAVRGAVC-NG.RRT.SAIDQQLVRQLK..................
#=GR A3ZQH6_9PLAN/4-223       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D5MKC5_9BACT/3-229                  ...............................LMISVRDEQEAAAAL..AG..GADIIDVKNPAEGSLGAGRPETISAIVR........TVRG....................A...TPVSASIGDVPNLP.................GTVALAGLGAATC.G.....VRFVKVGLLG.....ARTGAEAANLLDAVSGALR.MAN....GTV.GLVACVYADAAL..VGSVDPLE.LPGAAAPF......-.VEGCLIDTAIKD.GRT....LFQCLPEETITRFIQQCHDRELFCALAGSLQQADLSKALAL..GADIVGVRTAACEGG.QRS.GSISTTLVERL-k.................
#=GR D5MKC5_9BACT/3-229       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
B8GDK9_METPE/3-224                  ...............................LLVSPSSPEEAQRSL..A-..-ADIIDVKKPSEGSLGANFPWVIRAIKA........MTEK....................-...-PVSAAIGDFDNKP.................GGAALAAYGAACA.G.....ADYIKVGLM-.....LNDPAAAAEVIEGVVRAVK.DDF....PEK.YVVIAAYSDYER..LGTISPFD.MTPLAAAA......G.ADFAMIDTGRKD.RRS....TFEFMDTEALTRFTAMNRDAGLGTALAGSLVFEDLPVLKRI..DPEIIGVRGMVC-GG.DRN.ATIREDLVAR--ai................
#=GR B8GDK9_METPE/3-224       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
F0SRJ3_RUBBR/4-245                  ...............................LLISVRNAAEAGIAL..AG..GCDVLDVKDPSAGSLGQPALNTLAEILEt.....lkHLQS....................S...IPTSCALGELVDWS................pD----PVAMFTLN.R.....LSYLKIGPAG.....LGKFDDWADRFATLQQQFR.QAG....VNQpRWIAAFYLDFEA..AASFDPLAvLTETKLRKqlcdrlG.CAGILLDSFDKQ.GPSaaelILDRRRTQTLRDLLATARELGLMTAFAGRLSFEDVRTLQAAriQPDLFAVRSAVCLEN.QRQ.AGIEAARVRQL-t.................
#=GR F0SRJ3_RUBBR/4-245       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0H4CIM5_9ACTN/3-233              ...............................LLISPDSVEEALDCA..KAaeHLDIVDVKKPDEGSLGANFPWVIREIRD........AIPA....................G...TPVSATVGDVPYKP.................GTVAQAALGAVVS.G.....ATYIKVGLYG.....CTTPDQGIEVMRAVVRAVK.DHR....PEA.LVVASGYADAHR..VGCVNPLA.LPDIAARS......G.ADAAMLDTAVKD.GTR....LFDHVPPDVCAEFVRSAHARGLLAALAGSVRQSDLAPLTGI..GTDIVGVRGAVCEGG.DRNaGRIQPHLVAAF-r.................
#=GR A0A0H4CIM5_9ACTN/3-233   pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
Q2FS88_METHJ/3-224                  ...............................LLVSPATIEEAKKAL..S-..-ADIVDVKRPEEGSLGASFPWIIRAIKD........LTHK....................-...-PVSAAIGDFDYKP.................GGAALTALGAAAA.G.....ADYIKIGLM-.....FDGIEEAEMLIHSVTRAVK.ETY....PEK.MVVIAAYSDWER..LETISPYD.MAPLAAKA......G.ADISMVDTGIKD.GKS....TFEFMDETRLVEFTKLNQKLGIKTALAGSLKFEDIEILKRI..NPDIIGVRGMVC-GG.DRR.AMVQEELVLK--av................
#=GR Q2FS88_METHJ/3-224       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
C5CPV3_VARPS/5-221                  ...............................MLVSVRSVDEALLAA..RG..GADFIDLKEPNEGALGGLPVATIGAIVS........ALRG....................HgigLPVSATIGDLPMHA................lDAILAQVDAVGAC.G.....VDYVKVGIER.....GPKALAVLDALAA----CH.---....--W.PVVPVFIGDHG-..----LDAA.LTAHACTL......G.FPGLMVDTADKE.AGS....LFDAVPMADLRAFLAQVRAAGQMAGVAGALRTAHVPLLQSL..APDFAGFRSAVC-VG.DRK.AALSPERLAAL-a.................
#=GR C5CPV3_VARPS/5-221       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D7DS38_METV3/3-231                  ...............................ILVSPKNIEEAREAE..AG..GADIIDVKNPPEGSLGANFPWVIKETRD........ITPK....................D...KLVSAAIGDVPFKP.................GTVSLAAYGAAMS.G.....ADYVKVGLWG.....PRSYQEAVEVMKNVSKSVK.LAG....EDK.IVVAAGYADAYR..IGAVDPLV.IPKVARDS......G.CDVAMLDTAVKD.GKT....LFDHLSIDLLKEFVEESHSYGLKVALAGSIKKEEIPMLKQI..NCDIVGVRGAACTKG.DRNeGTIQKDLVVEL-v.................
#=GR D7DS38_METV3/3-231       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A2ST93_METLZ/3-225                  ...............................LLVSPSSIDEAKFCL..D-..-ADIIDVKRPAEGSLGANFPWVIREIKR........MASS....................-...TPVSAAIGDYRPTP.................GNASLAAYGAACA.G.....ADFVKIGLM-.....FSDKQAAKEVIEAVVRAVK.EPF....PEK.TVVIAGYSDYER..LGAISPFD.ISPLAAEY......G.ADFSMIDTGMKD.GKS....TFEFMNEDSLTDFTDLNRSLGIGTALAGSLKFADLPILKEI..DPEIIGVRGMVC-GG.DRT.TMVQESLVKK--ai................
#=GR A2ST93_METLZ/3-225       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
Y6440_STRCO/3-233                   ...............................LLISPDGVDEALDCA..KAaeHLDIVDVKKPDEGSLGANYPWVIREIRA........AVPA....................D...KPVSATVGDVPYKP.................GTVAQAALGAAVS.G.....ATYIKVGLYG.....CATPEQAVEVMRGVVRAVK.DHR....ADA.FVVASGYADAHR..IGCVNPLS.LPDIARRS......G.SDAAMLDTAIKD.GTR....LFDHVPPDVCAEFVRRAHDCGLLAALAGSVRSGDLGELARI..QTDIVGVRGAVCEGG.DRTtGRIRPHLVAAF-r.................
#=GR Y6440_STRCO/3-233        AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
MFNB_METMP/3-231                    ...............................LLVSPKDVAEAYEAI..EG..GADIIDVKNPPEGSLGANFPWVIKETRE........ATPE....................G...MLVSAAIGDVPYKP.................GTVTLAALGATVS.G.....ADYIKVGLYG.....TRSYQEALDVMKNVTKAVK.DAG....ENK.IVVAAGYADAYR..VGAVDPLV.IPKVARDA......G.CDVAMLDTAVKD.GKT....LFDHMDLDLLREFVEETHKYGMKCALAGSIKIEEIPMLKEI..GCDIVGVRGAACTQG.DRNaGRIQKDLVKEI-v.................
#=GR MFNB_METMP/3-231         AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
H8GQZ3_METAL/4-220                  ...............................MLASVNSLAEAQLAY..RA..GADIIDLKQPAAGALGALPPEEVARIRA........WCAG....................K...IPVSATVGDLPMQP.................DLIFDTAQAMAAT.G.....VDYVKIGFFP.....GGDWSGVAHRLTVLTERGH.---....---.ALIAVLFGDAS-..----PDPA.FIPTLQQA......G.FVGVMLDTMDKS.RGS....LPEILTPAEIERFVEAARARHLLCGLAGSLRLKDIPALLRY..RPNYLGFRGALCVRH.HRT.AELDGKA-----aalik.............
#=GR H8GQZ3_METAL/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
MFNB_METKA/5-233                    ...............................LLVSPVNRDEALEAV..EG..GAHIIDVKNPEEGSLGANFPWVIREIME........VVPE....................D...REVSATVGDVPYKP.................GTVAQAVLGVAAV.G.....VDYAKVGLYG.....TKTEEEALEVMRACSRAVR.EFG....YDT.RVVAAGYADAHR..VGSLDPMS.VPEVAAEA......E.CDVAMVDTAVKD.GKR....LFDFLSEEEVGEFVDSAHEHGLEVALAGSLRHEDMPIVRDL..GADIVGVRGAACERG.DRNrGAIRSHLVRKL-a.................
#=GR MFNB_METKA/5-233         AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
G7ZAY4_AZOL4/4-220                  ...............................MLASVTDPEEADLAV..EA..GADLIDLKNPREGALGALPADLIRACLA........TVSG....................R...RPVSATIGDLPMDP.................DITAMAVSRTAAT.G.....VDIVKMGIVA.....GGDPAACIEAAALARGAS-.---....---.ALVGVILADLT-..---PPTPD.LVHAMADA......G.FIGVMLDTGLKD.GRS....LRDHLSTDALADFIGRARDAGLSAGLAGSLRLADIPPLAAL..GPSILGFRGALCQGG.ARR.EVMDPDRIAEV-i.................
#=GR G7ZAY4_AZOL4/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
N0BEP7_9EURY/4-231                  ...............................VLVSPMSIDEAYECL..KG..GADIIDVKNPKEGSLGANFPWVIKEIGE........IVKK....................E..gKELSATTGDLDFKP.................GTASLAALGAAVA.G.....ADYIKVGLYG.....VKNKEQAYEILKNVTRSVK.DFD....ADK.KVVGAAYADFHR..INAISPFD.LPEAGQMA......E.VDGIMIDTAIKD.GLT....LFDHLKEPQLQEFVETARENGMFCALAGSINWEHLPVLKKI..SPDIIGVRTIVC-ES.GRQ.SKIKSELVERL-m.................
#=GR N0BEP7_9EURY/4-231       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
E8W242_STRFA/3-233                  ...............................LLISPDSVEEALDCA..KAaeHLDIVDVKKPDEGSLGANYPWVIRDIRA........AVPA....................D...KPVSATVGDVPYKP.................GTVAQAALGAAVS.G.....ATYIKVGLYG.....CTTPEQAVEVMRGVVRAVK.DYR....PDA.FVVASGYADAHR..IGCVNPLA.LPDIARLS......G.SDAAMLDTAVKD.GTR....LFDHVPPDACAEFVRLAHEADLLAALAGSIKAEDLATLTGI..GTDIVGVRGAVCERG.DRTtGRIQPQLVAAF-r.................
#=GR E8W242_STRFA/3-233       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
V6JRN2_STRNV/3-233                  ...............................LLISPDGLDEALDCV..KAaeHLDIVDVKRPAEGSLGANFPWVIREIRA........AVPA....................D...KPVSATVGDVPYKP.................GTVAQAALGAVVS.G.....ATYIKVGLYG.....CTTTEQATEVMRGVVRAVK.DYR....PDA.FVVASGYADAHR..IGCVNPLS.LPDIARRS......G.SDAAMLDTAIKD.GTR....LFDHLPPDVCARFVKLAHEADLLAALAGSVKVGDLGVLTGI..GTDIVGVRGAVCEGG.DRDtGRIRPELVAAF-r.................
#=GR V6JRN2_STRNV/3-233       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
F3NDC8_9ACTN/3-233                  ...............................LLVSPDSVEEALDCA..KAaeHLDIVDVKKPDEGSLGANYPWVIRAIRE........AVPA....................D...RPVSATVGDVPYKP.................GTVAQAALGAVVS.G.....ASYIKVGLYG.....CTTPEQAVEVMRGVVRAVK.DHR....PDA.FVVASGYADAHR..IGCVNPLA.LPDIARRS......G.SDGAMLDTAVKD.GSR....LFDHTPPEVCARFVELAHEAGLLAALAGSVKAPDLEELARM..GTDIVGVRGAVCEGG.DRNaGRIRPSLVAAF-r.................
#=GR F3NDC8_9ACTN/3-233       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0F7JUH0_9GAMM/4-218              ...............................LLASICSVEEAAIAL..HA..YADIIDCKDPTRGALGALSREQIANIVD........YVDG....................K...RPVSATIGDLPADP.................DRIRMAVRNTASC.G.....VDYIKLGLFE.....EQGAADCIQALEEECAN--.---....--H.RLIAVCFADRF-..----NPLA.LLPLLSVY......G.FHGVMIDTADKH.RGR....LTDLWSPARLARFVDQAQRLGLICGLAGRLTLADIPTLLPL..GADYLGFRSALC-VS.GRS.SRVDHGAM----mrvr..............
#=GR A0A0F7JUH0_9GAMM/4-218   pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
I1XFK9_METNJ/1-157                  ...............................---------------..--..----------------------------........----....................-...-----------MQP.................EIISAAIRSMAET.G.....VDYVKVGLFD.....ESGLIQCIQQLEPTIRSLK.K--....---.PVIAVIFADQL-..----PQQK.LIPLLAKS......G.FAGVMLDTARKD.GQG....LLNHLSVEALQQFVVEAKSAGLLCGLAGALRIEDIETLSPL..QPDYLGFRSALCQQH.RRT.NLLDPELAKQI-q.................
Q12VF6_METBU/3-227                  ...............................LLVSPINTEEAVAAL..NG..GADIIDVKNPKEGSLGANYPWVIREIRD........AVEG....................K...RPISAALGDFSYKP.................GTAALAAYGAAAA.G.....ADYVKIGLYD.....ITTEEQAYEMLTGIVESVK.D--....MDV.TVVACGYSDHER..INSINPKL.LPAIGEKA......G.VGLVMVDTGLKD.GRS....TFEFMTEEDLIEFVNDAHSRGLETAIAGTIKFDDIPALKRI..QPTIVGVRGIVC-GG.DRS.TSIKQELVEKLR..................
#=GR Q12VF6_METBU/3-227       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0A8K339_9RHIZ/4-219              ..............................f-LASVRNAAEAECVL..AA..GADIVDLKEPDEGALGAVAPSVVRACLR........TIGG....................R...KPVSATVGDLPMNP.................AVVTDAVAATAEL.G.....VDTVKLGILV.....GGDPWGCFEVLGSLGTPA-.---....---.DLVLVFFGDMP-..----TDID.PVEAARAS......G.ANGVMLDTAGKE.RGS....LTDHMTLGEIGRFVDRAHHAGLQVGLAGSLRPHHVQPLLGL..RPDVIGFRGALCEQS.ARG.SNLDPNACAE--ig................
#=GR A0A0A8K339_9RHIZ/4-219   pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
C7PZG9_CATAD/3-233                  ...............................LLISPADVEEARDCA..KAsrHLDIVDVKKPDEGSLGANFPWVIREIRD........IVPA....................D...KPVSATVGDVPYKP.................GTVAQAALGAVVS.G.....ATYIKVGLFG.....CTTPDQAVTVMRAVVRAVK.DYR....PDA.LVVASGYADAHR..VGCVNPLA.VPDIAGRS......G.CDAAMLDTAIKD.GTR....LFDHVPPDLCAEFVRRAHDTGRLAALAGSVRAEDLGTLTAI..GTDIVGVRGAVCERG.DRTtGRIQPHLVAAF-r.................
#=GR C7PZG9_CATAD/3-233       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
G4T028_META2/21-237                 ...............................MLASVSKLDEALRIL..NF..EVDIIDLKQPSQGALGALDTMTVARIVK........AING....................Q...CPISATVGDLPMIP.................EVIVSAVTDMAAT.G.....VDYIKIGFFP.....GGDWQGTLDALAPLAQAG-.L--....---.ALIGVLFADNE-..----PELH.TVAAFKKA......G.FKGVMLDTMDKS.SGS....LPHVLPDDAIAEFVSKCNELNLLCGLAGSLRAVDIPDLLRR..KPDYLGFRGALCRRH.DRT.SHLDDDAILAV-k.................
#=GR G4T028_META2/21-237      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
H2JMK4_STRHJ/3-233                  ...............................LLISPDGVEEALDCA..KAaeHLDIVDVKKPDEGSLGANFPWVIREIRD........AVPA....................N...KPVSATVGDVPYKP.................GTVAQAALGAVVS.G.....ATYIKVGLYG.....CTTPDQGIEVMRAVVRAVK.DHR....PDA.LVVASGYADAHR..IGCVNPLA.VPDIAARS......G.ADAAMLDTAVKD.GTR....LFDHVPPDVCAEFVRLAHASGRLAALAGSVTQADLGPLTHI..GTDIVGVRGAVCEGG.DRNaGRIQPHLVAAF-r.................
#=GR H2JMK4_STRHJ/3-233       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0M2U0R3_9FIRM/3-231              ...............................LLVSVVDAAEALAAL..EG..GADIIDVKNPLEGALGANFPWRIREIAG........LMPG....................G...RELSATLGDAACLP.................GAYSLAAAGAAWC.G.....ARYVKVGLYG.....MENGEAAIYFLRQVNRAIR.LVT....GEQgQVIAVGYADAGR..VGAMPPAE.LPRVAAEA......G.VHGCMLDTAVKD.GAS....LLRVMTMHELARFVRETRARRLVCGLAGSLGSEDLPAVREL..GPDVVGVRSAAC-RG.DRVrGRVDSELVSEL-r.................
#=GR A0A0M2U0R3_9FIRM/3-231   pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
N0B6U5_9RHIZ/12-227                 ..............................f-LASVTSADEASLAL..AG..GADVIDCKDPSAGALGALPHAVVREVAA........RVAG....................R...LLVSATVGDLPPES.................GALVEAASAMART.G.....VDIVKIGFFG.....DGDARPAIAALGR-VKHQK.V--....---.RLVAVLMADQA-..----PDYE.LIPYLAAH......G.FAGVMLDTADKS.GGR....LTTMLPAGGLSKFVSSARNSNLMCGLAGSLRMEDIAGLASL..GPDVLGFRGALC-ET.GRS.SKLDPTRVAAI-r.................
#=GR N0B6U5_9RHIZ/12-227      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D5E8I4_METMS/3-229                  ...............................LLVSPINNEEAISAL..KG..GADIIDVKNPKEGSLGANFPGVIKAVKD........AVGG....................Q...KPISAALGDFNYKP.................GTAALAAYGAAAA.G.....ADYVKIGLYD.....IQTEEQAYEMLAGITEAVR.TMD....NVP.KVVACAYSDYAR..INSIDPAL.LPAIGAKA......G.VDLVMVDTGVKD.GRS....TFEFLNEAHLKDFVEKAHANGLETALAGSIKFDDIEAIKDI..KPDILGVRGIVC-GG.DRS.TSIKQELVEQLR..................
#=GR D5E8I4_METMS/3-229       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D3S2M0_FERPA/3-230                  ...............................VLVSPMNLEEALECI..RG..GADIIDVKNPAEGSLGANFPHVIKEVSE........IVKK....................S..gREVSATIGDMEFKP.................GTASLAALGAAYS.G.....ADYIKVGLYG.....VRNEREVYEMMKEVVRAVK.DFD....EGK.KVVAAAYGDYTR..VNSVSPFE.IPEASYKA......G.ADGIMVDTAIKD.GKD....IFSFMKFEELERFIEEAHKRGMFCAIAGSLKWEHIDVLKKL..NPDIIGVRTMVC-ES.GRN.SSIKAELVEKL-t.................
#=GR D3S2M0_FERPA/3-230       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
C6XEF2_METGS/4-218                  ...............................LLASVNSLQETELVL..S-..LADIIDLKNPAMGALGALPIEVIEQIVR........YVDG....................R...KPISATIGDLVMEP.................KPVLAAIQAVAAT.G.....VDIVKVGMFA.....-GEQLACIEAIKPIARSG-.T--....---.KVVAVLFADSQ-..----QTFL.PLEVFAEA......G.FYGVMQDTAIKN.GSS....LLDHQDLPQLRAFVQEARVNDLICGLAGSLRVSDIETLAAL..KPDYLGFRSALCQNG.NRT.KTISATSAAA--vq................
#=GR C6XEF2_METGS/4-218       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
B2JX52_BURP8/4-220                  ...............................LLASVRSAEEALDAA..GA..GADLIDLKEPREGALGGVSLDNIWRIAR........TLRS....................RhpvKPISATIGDLPPDA................iETIAARATEVGET.G.....VDFVKVGVVP.....GPHARACLTRIAGLQAA--.---....---.-VLPVLLCDDG-..----VDAA.LVEHAVWL......R.FVGIVFDTAGKT.GRT....LFDCIDAATLARYIAMIRASGAMACIAGSLGWTQLDGIRAL..APDVAGFRTALC-EN.GRI.SRLDPRRVAQW-a.................
#=GR B2JX52_BURP8/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0M2GBH5_9ACTN/3-233              ...............................LLISPDGVEEALDCA..KAaeHLDIVDVKKPDEGSLGANFPWVIREIRE........AVPA....................E...KPVSATVGDVPYKP.................GTVAQAALGAVVS.G.....ATYIKVGLYG.....CTTPDQGIEVMRAVVRAVK.DHR....PEA.LVVASGYADAHR..IGCVNPLA.LPDIAARS......G.ADAAMLDTAVKD.GSR....LFDHVPPDVCAEFVRLAHASGLLAALAGSVKQTDLGPLTRI..GADIVGVRGAVCEGG.DRNaGRIQPHLVAAF-r.................
#=GR A0A0M2GBH5_9ACTN/3-233   pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0E3S508_9EURY/5-231              ...............................LLVSPINKEEAIIAS..RG..GADIVDVKNPKEGSLGANFPWVIRDVKE........VVNG....................R...QPISATIGDFNFKP.................GTAALAALGAAAA.G.....ADYIKVGLYD.....IQTEAQALELLTKITRAVK.DYD....PSK.KVVAAGYSDYKR..INSISPIL.LPAVAAEA......G.VDVVMVDTGIKD.GKS....TFEFMDEKELIEFTDLAHEHGLESAIAGSLKFEDLPVLERI..GPDIIGVRGMVC-GG.DRM.TTIRQELVEKL-v.................
#=GR A0A0E3S508_9EURY/5-231   AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
Q3JF34_NITOC/4-221                  ..............................w-LASARNLEEASYLL..AE..GPDIIDFKEPKRGVLGALPPETVRQAVA........LIGG....................R...CQTSATIGDFFVES.................SQISQGVLEIAAT.G.....VDYVKIALFS....nTQQAADCLISLQPLAARG-.V--....---.SMIGVIFADKQ-..----PDFS.WIHLIKQA......G.FKGIMLDTAVKD.GRG....LLSHLSLPELDNFIKVARNANLVSGLAGSLSIQDIPKLLSL..KANYLGFRSALCTAG.NRC.YRLDPKAVLSI-k.................
#=GR Q3JF34_NITOC/4-221       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0C1TN64_9ACTN/11-177             ...............................LLVSVFGPQEAREAV..LG..GARIIDSEDPRS-ALGTIKPRRIMDIADav...lavR--Rd..................lP...VQLSTNIGEDQLLHrragnglaiakspyetaGKAAQAALGVAVSmGnqvhpCPIVKVGLDG.....-MGVDRLTDVLGEITATLR.RADg..lGRT.RVMSVLFG----..--------.--------......-.------------.---....-----------------------------------------..---------------.---.------------qdldlwdtrktlpqvrra
I4BX62_ANAMD/10-237                 ..............................f-LASVVSKEEAAEAL..KV..QVDVIDVKNPAEGALGAALPETITEIRG........VVPK....................A...IPVSAAIGDMPYLS.................GTAALAAVGAACA.G.....ADMVKIGLYG.....AKTSDEALNLLCSVANALK.MYF....PTS.LLVAGAYADAQI..FGGINFLD.VPALAAKA......G.AAGCLLDTFDKSfGHN....LLEIASMEAIGDFVSACREWGLFSALAGSLKLEDVPLLLPL..RPDYLGFRGALC-EG.GRS.GKLSSRKVLEI-s.................
#=GR I4BX62_ANAMD/10-237      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D5C442_NITHN/4-220                  ..............................w-LASVRNLEEVSSLL..AE..GPDIIDLKEPKEGALGALSSETICQAVA........LIGG....................R...CPTSATIGDLPMEP.................APICHAVEQIAAT.G.....VNYVKIGLFP.....DDRVPDCLIALQPLAVQG-.---....--I.SLVGVMFADKR-..----PDFS.WISLMEKV......G.FTGAMLDTAAKD.GHN....LLSHLSLAELSGFVQTARSGGLVSGLAGSLSFEDIPKLLPL..GADYLGFRSALCCAG.QRQ.SSLDPKAIAL--lk................
#=GR D5C442_NITHN/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D6KD14_9ACTN/2-232                  ...............................LLISPDSVEEALECA..KAaqHLDIVDVKKPDEGSLGANHPWVIRAVRD........AVPA....................D...KPVSATVGDVPYKP.................GTVAQAALGATVS.G.....ATYIKVGLYG.....CTTPDQAVEVMRGVVRAVK.DFR....PDA.LVVASGYADAHR..IGCVNPLA.LPDIARRS......G.SDGAMLDTAVKD.GTR....LFDHTPPQVCAEFVRLAHEAGLLAALAGSVKAGDLAELAGM..GTDIVGVRGAVCEGG.DRNaGRIRPELVAAF-r.................
#=GR D6KD14_9ACTN/2-232       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D2QXD0_PIRSD/4-224                  ...............................LLVSVRDVREATLAL..EA..GVDLLDVKEPSAGPLGFASLDTLLSIAQi.....arKLAP....................E...VPLSAAIGELADPL.................ALPLEQL-----H.P.....YRYLKLGLAG.....-MARSPWPSQWEHVRGQLA.D--....-QS.QLVPVIYADFPS..AQAPPPNE.VLELAIAQ......A.ASVLLIDTWDKD.RGN....LFAAISVAELSAIIEQARAAEIQVVVAGKLALADVPQLRAI..GARYWGVRTAVC-ES.TRD.GTLAPEKIAAW-k.................
#=GR D2QXD0_PIRSD/4-224       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A7I923_METB6/3-224                  ...............................LLVSPSSISEAHSSV..A-..-ADIIDVKKPSEGSLGANFPWVIREIKS........FANK....................-...-PVSAAIGDFPHKP.................GGAALAAYGAACA.G.....ADYVKIGLA-.....FSGKDKAREVIEAVTKAVK.DEF....PEK.FVVIAGYSDYER..MGSISPFE.IAPLAAAC......G.ADYAMVDTGIKD.GRS....TFSFMDETTLARFTKQNRELGIGTALAGSLVFADIDALKRI..NPEIIGVRGMVC-GG.DRN.ATIREDLVKT--al................
#=GR A7I923_METB6/3-224       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A7IMS7_XANP2/15-237                 ...............................LLASVADLAEMEVAL..GA..GADIVDLKNPAEGALGAWAEAPLKAAVAr.....wrAAGC....................V...TGLSATVGDQPLDA.................ATILAAARRTAST.G.....VPLVKIGFPL.....--PLDGAGAALAPVLDALR.PLA....LET.RLIAVLFADQD-..----PDLS.TIAQFAEA......G.FHGVMLDTADKA.AGG....LLAHLPVPRLAGFVAEARAAGLLTGLAGSLKLQDIAPLATL..KPHYLGFRGALC-AT.GRT.SALDPAQLARV-r.................
#=GR A7IMS7_XANP2/15-237      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
I0HWI2_RUBGI/4-220                  ...............................MLVSVRDPHEALAAA..AA..GADFIDCKDPSAGALGALPTATVAAIVR........LLAC....................Gf.gGPTSATIGDVAADEd...............pAALLARVAAMAAT.G.....VCFVKVGIEP.....GP---LAAARLRALAG-CG.H--....---.TVVPVFVADRG-..----LDMA.LVALALEL......R.FRALMIDTADKN.AGS....LFDLVPPAALAAFVEAARAAGVPVGLAGALRTPDLPRLAAL..APHFAGFRSAVC-SS.GRA.GTLEPARVRAL-a.................
#=GR I0HWI2_RUBGI/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
G7ZBV6_AZOL4/4-224                  ..............................w-LASVATAAEIPLIL..PA..GPDFLDLKDPAAGALGAWAVEDIAATVRe.....laALPG....................R...PRLSATIGDHPMRP.................EAVEPAARRIAAT.G.....VDFVKIGFAP.....DGAPDRCIDALAPLAADG-.V--....---.QLVAVLFADLW-..--PPDPGClPIDRLSAA......G.FRGAMLDTAGKR.-HG....LRHYWHDAQLSSFVCCARAHGLLTGLAGSLRVADIPALSSL..SPDYLGFRGALC-GG.KRT.AGIDPQAVARV-a.................
#=GR G7ZBV6_AZOL4/4-224       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0B5IP84_9ACTN/3-233              ...............................LLISPDGVEEALDCA..KAaeHLDIVDVKKPDEGSLGANFPWVIREIRD........AVPA....................D...KPVSATVGDVPYKP.................GTVAQAALGAVVS.G.....ATYIKVGLYG.....CTTPEQGVEVMRAVVRAVK.DHR....PEA.LVVASGYADAHR..IGCVNPLA.LPDIAARA......G.ADAAMLDTAIKD.GTR....LFDHVPPDACAEFVRRAHASGLLAALAGSVKQADLGPLTRI..GTDIVGVRGAVCAGG.DRNaGRIQPHLVAAF-r.................
#=GR A0A0B5IP84_9ACTN/3-233   pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
L0DCN6_SINAD/4-221                  ...............................LLVSVRSVEEASDAL..AG..GASIIDIKEPARGPLGRADTEVWQAIRE........TLPT....................G...VCLSVALGELPEWT.................DQPDP--ARSAFT.G.....ISYRKLGLAG.....------VGPDWKAIWAKLR.DRW....REGpAWVAVVYSDWQR..ANAPQPVDvLEEALAVG......E.CTGILIDTWDKG.RPS....TVDHSWLP----WLAQARQGGLTIALAGGLNDSRIERLGPL..DPDWIAVRGAACREG.DRG.SGLDPVRVARL-a.................
#=GR L0DCN6_SINAD/4-221       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
Q1H0Z0_METFK/4-220                  ...............................LLISVTSVEEALLAL..EG..GADIIDMKNPSQGALGALPLSVVSEAVI........AVGG....................R...RITSATTGDLPMSP.................TLICHAVMQMAAT.G.....VDIIKIGFFG....nEQENIACIHAVQPLIARHN.L--....---.AVVAVLMADLS-..----PQFS.LLPLLREA......G.FWGVMLDTANKD.GRS....LLAHLDMESLAIFLRMAE--GMQTGLAGSLNMENIENIVKM..KPSYIGVRGAVCMGF.DRV.AKLCKDKVSAL-n.................
#=GR Q1H0Z0_METFK/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0F7FYD5_9ACTN/10-240             ...............................LLISPDGVEEALDCA..KAaeHLDIVDVKKPDEGSLGANFPWVIREIRD........AVPA....................H...KPVSATVGDVPYKP.................GTVAQAALGAAVS.G.....ATYIKVGLYG.....CTTPEQGIDVMRAVVRAVK.DHN....PDA.LVVASGYADAHR..IGCVNPLA.VPDIAARS......G.ADAAMLDTAIKD.GSR....LFDHVPQDACAEFVRLAHASGRLAALAGSVKAADLGPLTRI..GTDIVGVRGAVCEGG.DRNaGRIQPHLVAAF-r.................
#=GR A0A0F7FYD5_9ACTN/10-240  pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
K4MDK2_9EURY/3-229                  ...............................LLVSPISPEEAIAAH..KG..GADIIDVKNPKEGSLGANFPWVIRSVKE........AIGS....................Q...KPISATIGDFNYKP.................GTASLAALGAAVA.G.....AHYIKVGLYD.....IQTEEQALEMLTNITRSVK.DLD....PSK.KVVASGYSDYRR..INSISPHL.LPAIGAQA......G.VDVVMVDTGIKD.GRS....TFEFMTEEELTMFTGAIRDHGLESALAGTLKFEDLSMLRRI..RPDIIGVRGMVC-GG.DRT.SVIQEELVAKLK..................
#=GR K4MDK2_9EURY/3-229       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
MFNB_METTH/3-230                    ...............................LLISPINTEEALEAI..EG..GADIVDVKNPAEGSLGANFPWVIRRVRE........MTPE....................D...MLVSATLGDVPYKP.................GTVSLAAMGALVS.G.....ADYIKVGLYG.....TRNYDEAVDVMKNVVRAVK.D-Q....SDA.IVVAAGYADAHR..VGAVEPME.IPRVAADS......G.ADLAMLDTAVKD.GKT....LFDFMDMEKLESFVSAARDHGLKSALAGSVGREHLKPLHEI..GCDVVGIRGAACVGG.DRNtGRIHRDAVREL-k.................
#=GR MFNB_METTH/3-230         AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
MFNB_METAC/3-229                    ...............................LLVSPINREEAIIAS..LG..GADIVDVKNPKEGSLGANFPWVIRDVKE........VVNG....................R...QPISATIGDFNYKP.................GTASLAALGAAVA.G.....ADYIKVGLYD.....IQTEAQALELLTKITLAVK.DYD....PSK.KVVASGYSDYKR..INSISPLL.LPAVAAEA......G.VDVVMVDTGIKD.GKS....TFEFMDEQELKEFTDLAHEHGLENAIAGSLKFEDLPVLERI..GPDIIGVRGMVC-GG.DRR.TAIRQELVEKL-v.................
#=GR MFNB_METAC/3-229         AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
B8EKF6_METSB/4-219                  ...............................MLASVINGAEAETAL..AS..AVDMIDLKDPARGALGALPAGLVASIVA........TVAG....................R...KKTSAAAGDQFAAP.................ADAVEAARALVAT.G.....VDFVKIGLQG.....GAAGAAIVDALGAHKGD--.---....--A.ALIGVLFADQN-..----PDLD.LLNRMAER......G.FKGAMLDTFEKG.AGR....LLDHMDVAALAPFVDRCRELGLICGLAGSLEAPDVPRLLPL..RPDYLGFRGSLCKGG.ERG.GALDLAAVAMI-r.................
#=GR B8EKF6_METSB/4-219       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
U6ECS5_9EURY/3-231                  ...............................LLISPINTQEAREAI..EG..GADIIDVKNPKEGSLGANFPWVIKNIRE........ITPK....................D...MQVSATLGDVPYKP.................GTVSLAAAGAVVS.G.....ADYIKVGLYG.....TKNYSQALEVMENVVKAVH.EFN....EDA.TIVASGYADAHR..VGAVDPME.IPRVAADS......G.ADLAMVDTAIKD.GKT....LFDFMNEEKISKFTTEIHDYGLKSALAGSVTREQLPLLAEL..GCDVAGVRGAACVGG.DRNsGHIHHEAVASL-k.................
#=GR U6ECS5_9EURY/3-231       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D9XMZ4_9ACTN/3-233                  ...............................LLISPDSVEEALECA..KAaeHLDIVDVKKPDEGSLGANFPWVIRAIRD........AVPA....................D...KPVSATVGDVPYKP.................GTVAQAALGAAVS.G.....ATYIKVGLYG.....CTTPEQAVDVMRGVVRAVK.DHR....PDA.FVVASGYADAHR..IGCVNPLA.LPDIARRS......G.SDGAMLDTAVKD.GTR....LFDHTPPDVCAEFVRLAHEAGLLAALAGSVKAGDLGELARM..RTDIVGVRGAVCEGG.DRDaGRIRPELVAAF-r.................
#=GR D9XMZ4_9ACTN/3-233       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0J6RJ87_9RHIZ/11-219             ...............................LLVSVRDAAEAALAR..DG..GADLIDGKDPERGALGALPAETVRAIVA........VSGD....................-...RLTSAVAGEPRDAA.................-EASGCLAALAGT.G.....VGYLKIAWAP.....---GRDATGLLLP----AG.R--....---.PVIAVLFAEDG-..----PDGA.DVPGLAAA......G.FSGAMIDTRGKD.GRR....LTDHLALPRLAGFTAACRAHGLLSGLAGSLRLDDIPDLATL..RPGYLGFRGGLCAAA.DRT.GRLDPARIAE--aa................
#=GR A0A0J6RJ87_9RHIZ/11-219  pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
L0HGW6_METFS/3-224                  ...............................LLVSPSSIDEARHSV..A-..-ADIIDVKKPSEGSLGANFPWVIREIKE........FAQK....................-...-PVSAAIGDFDFRP.................GGAALAAYGAACA.G.....ADYVKIGLA-.....FEGKEQARDLIAAVVRAVK.EPF....PRK.FVVIAAYSDYER..MHTISPFD.MAPIAAEC......G.ADFAMIDTGIKD.RQS....TFAFMDEKALLSFTEGNRKLGLGTALAGALKFEDLDALKRI..NPEIIGVRGMVC-GG.DRN.ATVREDLINK--al................
#=GR L0HGW6_METFS/3-224       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D7DPW6_METV0/15-236                 ...............................LLISVTTIEEAQIAL..EN..GADIIDLKEPSLGALGALPIETIQAIVT........YVKNtk...............nadA...KLTSATIGDLPMQP.................ELLLAHVTQLATT.G.....VDIIKIGFFQ.....TDDYQLSLDALKSVAHA-G.T--....---.KLIAVLFAETM-..----YPQG.LIAAIKYA......G.FMGVMLDTAKKN.GLT....LLDYYSQEQRAIFAKTVLGHNLQLGLAGSLKPQHVALIKEI..SPSYIGFRGGVCNDN.QRN.LALDAAKIKAV-r.................
#=GR D7DPW6_METV0/15-236      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
E1TEU8_BURSG/4-220                  ...............................LLASVRSHDEAFDAA..RA..GADLIDLKEPNMGALGGVSTGEIERIVR........ELRA....................RypvKPISATIGDLPPEA................lDEIAARVIEVSET.G.....VDYVKVGVTP.....GPAARRCIDHLANLPA---.---....---.AVVPVLLCDGG-..----MDSA.LVAHAASL......G.FAGVMFDTSAKD.GST....LFDHVDSDSLARWLRLIRERGAMCGLAGSLGWAQLAQIHAL..APDVAGFRTALCV-D.GRR.SRLDPQRVAQW-a.................
#=GR E1TEU8_BURSG/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A6C4I0_9PLAN/8-236                  ...............................LLVSVRNGAEIAPAI..AG..GCEILDFKDPRRGALGRVDDAILNAAIG........YCQQy.................svT...IPLSMALGELCEWN.................TG---QSSLSIPS.E.....ITFLKMGFSQ.....CNGSPHWISDWQNLIQRIE.ESS....KHQhQWIAVAYADWRR..ADSLSPYK.ILETACEN......G.CAGLLIDTFSKQ.NGR....LLDLLSPETLGEIIELARARQLKIALAGSLRIQDLEILSDL..APDIIGIRGAACLGY.SRT.SAIQESAIRDF-r.................
#=GR A6C4I0_9PLAN/8-236       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
H0HRB7_9RHIZ/4-219                  ...............................MLASVTGVAEAEIAI..SG..GVDIIDLKDPKAGALGAVAIDTIRQTVS........SVAG....................R...RATSAVCGDLPMEP.................EIIRAKAEEIAAT.G.....VDFVKVGFFP.....SGNIAACSAALAPLAART-.---....---.KLIAVMFADLA-..----PDFE.FLPVFAKD......G.FHGAMVDTAQKA.KGR....LLDHLPPERIPAFVDRARSHGLAVGLSGSLEAPDIPRLLPF..APDFLGFRGALCDQS.ERT.TPLSAEAVSQI-r.................
#=GR H0HRB7_9RHIZ/4-219       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
C6WV59_METML/4-225                  ...............................LLISVTDVNEAQIAL..VH..GADLIDLKDPHQGALGALPIQTIQEVVDfvg..inrSHP-....................Q...QYTSATVGDLPMQA.................DLIAQQVLRIANT.K.....VDFVKIGFFE.....SEDYQSCLDTLKHIA-HQG.V--....---.KLIAVLFAEMQ-..----YPEH.LIDDIKAA......G.FYGLMLDTAQKN.GGT....FMDYYTHEQMCLFATRVRSHAMAFGLAGSLNVQHLEKVRAY..SPSYIGFRGGVSMSN.QRK.LNLDAAKIKAI-r.................
#=GR C6WV59_METML/4-225       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
F5R8I0_METUF/1-224                  ...............................MLASVRDLDEARTVL..EA..GVDLIDLKQPADGALGALPADVIREVVA........FVAG....................R...TLTSATAGNVEPDA.................QAVQAAMARIATT.G.....VDYVKVGLFPa...gWQQGGRDYAAVHACLRGLA.P-L....AGA.RRIAVMFADLA-..----PPLD.LVDAVAAA......G.FDGVMVDTAHKT.GHS....LPDVAGVEWLSGFVERARAHGLLCGLAGSLRVAHIPALAQL..CPDYLGFRGALCAEQ.ARV.QALDVRAVL---gvr...............
#=GR F5R8I0_METUF/1-224       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
F7XPD0_METZD/3-229                  ...............................LLISPINPQEAISAA..NG..GADIIDVKNPKEGSLGANFPWVIRSVKE........AVGS....................L...KPVSATIGDFNYKP.................GTASLAALGAAVA.G.....SEYIKVGLYD.....IQTEEQALDMLSNITRSVK.DYD....PTK.KVVASGYSDYSR..VNSIAPFL.LPEIASRC......G.VDVVMVDTAIKD.GKS....TFDFMSEEELKKFTHLAQRSGLECAIAGTLKFDDLPIIGRI..APDIIGVRGMVC-GG.DRN.SCIQEELVKQLR..................
#=GR F7XPD0_METZD/3-229       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
MFNB_METS3/3-231                    ...............................LLISPINHEEALESI..KG..GADIVDVKNPKEGSLGANFPWVIRDIRE........ITPE....................D...KLVSATLGDVPYKP.................GTVSLAAMGAHVS.G.....ADYIKVGLYG.....TKDYDEAVEVMENVAKTIK.DVD....NDT.IVVASGYADAHR..VGAVDPME.IPKVAKDA......G.CDLAMLDTAVKD.GHT....LFDYLSIEDLEKFVNEAHSYGLKTALAGSVKKEQLKPLNDI..GCDVVGIRGAACVGG.DRNtGKIHHTAVAEL-k.................
#=GR MFNB_METS3/3-231         AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0D6JAY0_9RHIZ/17-235             ...............................MLASVVDAREATLCL..EG..GVDVIDCKDPSRGALGAVTPEAARAIVE........TVGG....................R...VPVSATIGDHPCEV.................GPIVEATLQAAAT.G.....VDYVKTGFLP.....GGDAAEVVRALGRLRGETG.K--....--A.QIVGVLFADAS-..----PDFE.LVAEMAAA......G.FAGVVLDTANKS.DGA....LPDVLAVDQLEHFVEIARAHEMFCGLAGSLRTRHIPALVRL..APDLIGFRGALCCEN.ART.GSLDLRAVVEI-r.................
#=GR A0A0D6JAY0_9RHIZ/17-235  pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0B4XC79_9RHIZ/4-219              ...............................MLASVQNRNEAEIVL..QA..GADIIDLKDPLRGALGAADIPQITDVVD........FVSG....................R...RPVSAACGELGGDL.................QALRARVEEVAAT.G.....VDFIKIGFLP.....SSRIGADAQALADIAGRK-.---....---.RLIAVVFADHR-..----YEEN.VMTSFAKA......G.FYGVMLDTDDKS.KGR....LLDHIPPDRISDFVAQGQRHGLMTGVAGSLEAPDIPRLLPG..KPDFLGFRGALCEGL.SRN.ADLDAEATAKI-r.................
#=GR A0A0B4XC79_9RHIZ/4-219   pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
B1M296_METRJ/14-222                 ...............................LLVSVRDPAEAEAAR..LA..GADLIDAKDPERGALGALDEDIVREIVA........RVSG....................G...AATSAVA-D----P.................--AAESVAALART.G.....VDWVKVGLAP.....-AELRDASALADRVAAAP-.---....--G.RLIAVLFAEDG-..----PAAR.HVPALAAA......G.FAGAMIDTAGKT.GAR....LPDLAAPSDLSAFTAACRAHGLMSGLAGSLRVIDIPGLCAH..RPDYLGFRGGLCRDF.DRR.NGIDPLRVAE--al................
#=GR B1M296_METRJ/14-222      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
J0RZ50_9EURY/3-224                  ...............................LLVSPSSIEEARSAL..A-..-ADIIDVKKPSEGSLGANFPWVIRAIKE........MAEK....................-...-PVSAAIGDFDYKP.................GCASLAAYGAACA.G.....ADFIKVGLM-.....FDGRDRAFDLARAVVRAVK.DDF....PEK.TVVIAAYSDYER..LGTISPFA.AAEAAAEA......G.ADIAMIDTGMKD.GKS....TFEFMDADTLASYTEENRSLGLATALAGSLKFEDLSALKII..DPEIIGVRGMVC-GG.DRS.CVIRPELVEK--al................
#=GR J0RZ50_9EURY/3-224       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
B0UG99_METS4/15-221                 ...............................LLVSVRDAAEAALAR..AR..GADLVDAKDPDRGALGGLPAATVRAIVA........ASPG....................-...GLTSAVAGEPRDAA.................E-AARMLAELRGT.G.....VDYLKIARP-.....----A-A---CRGLALPRG.A--....---.PVIAVLFAEDP-..IGAGDP--.--AALARA......G.FRGAMIDTRGKD.GRR....LTDHLPLPRLAAFLAECRRHGLLSGLAGSLALDDVPALASL..GPDYLGFRGGLCGGG.DRR.GALDPARIAE--aa................
#=GR B0UG99_METS4/15-221      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
C5B154_METEA/14-224                 ...............................LLVSVRGPDEALTAL..RA..GADLIDAKDPERGALGALPPETVRAIVA........GVGG....................R...AVTSAVAGDGTGRE.................--IAAAIATIAAT.G.....VDFIKIAVGG.....-ADDA----ALAEAAAQAP.---....--G.RVIGVLFAEDD-..----VAED.GPARLAAA......G.FVGAMIDTRGKS.GTT....LTSLMAAPQLAAFVAGCRTHGLMSGLAGSLGLGDIPVLARL..DPDYLGFRGGLCRAS.DRR.QALDGARVAQ--av................
#=GR C5B154_METEA/14-224      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
MFNB_META3/3-231                    ...............................LLISPKNIEEAKEAI..AG..GAHIIDVKNPPEGSLGANFPWVIEEVKN........ITPK....................N...LLVSATVGDVPYKP.................GTVSLAALGVAVS.G.....ADYIKVGLYG.....TKTYYEAVDVMEKVVKAVK.SVD....KNK.IVVAAGYADAYR..VGAVDPLI.IPKIARDS......G.CDVAMLDTALKD.GMS....LFDHLDEKLLKEFIEETRSYGLKSALAGSIKKEEIAILKKL..GCDIVGIRGAACSYG.DRNeGTIQKELVEEL-v.................
#=GR MFNB_META3/3-231         AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
H1YWT1_9EURY/3-224                  ...............................LLVSPSSVAEAKYSL..A-..-ADIVDVKKPSEGSLGANFPWVISEIKS........LSEK....................-...-PVSAAIGDYSFKP.................GSASQSAFGAASA.G.....ADYVKVGLM-.....FEGEGNALEFIEAVVKGVK.WRF....PEK.TVVIASYADYDR..VDAISPFE.MAPLAAKA......G.ADVAMIDTAVKD.GKG....LFDFLSESELTEFTEMNRSLSLQTALAGSLKFEDIETLKKI..NPEIIGVRGMVC-GG.DRS.AVIKPELVEK--al................
#=GR H1YWT1_9EURY/3-224       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D7E7G6_METEZ/3-229                  ...............................LLVSPINTEEAVSAC..NG..GADIIDVKNPKEGSLGANFPWVIKEVKD........SIDS....................K...KPISATIGDFNYKP.................GTASLAAYGAASS.G.....AEYIKVGLYD.....IQTEEQAYDMLENITNSVK.SYD....SNK.KVVACGYSDYQR..INSISPMK.LPEIGANA......G.VDLVMMDTGHKD.GKS....TFYFMSENTLSEFVDLAHSYGLETALAGSIKFDDLEPLKRI..KPDIIGVRGIVC-GG.DRN.TIVQEELVTKV-k.................
#=GR D7E7G6_METEZ/3-229       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
G8MDQ4_9BURK/4-222                  ...............................LLASVRSSDEAFDAA..NA..GADLIDLKEPGAGALGGVAIHDIARIVR........ELRA....................RyavRPISATIGDFPNDA................lDEITSRVLDVAAA.G.....VDYVKVGVSP.....GAGASACLRHLAGLPA---.---....---.AVVPVLLSDDG-..----VDRE.LAALAVRL......G.FVGIVFDTAHKD.GRT....LFDCVDVEGLAGCMADARSRGVMTAVAGSLGWGDLDRIRML..SPDIAGFRGALCGEGvGRG.GRLDPERVGRW-v.................
#=GR G8MDQ4_9BURK/4-222       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0F3IJ22_9GAMM/4-218              ...............................LLASVNSLDEARIAL..R-..YADIIDLKQPEQGALGALDVATITAIVA........ECKG....................R...RPLSATIGDLPFQP.................ECIIPAVQRLSKT.G.....VDYIKIGFFP.....HGDIANTLLELSQLSAGQ-.---....---.ALIAVLFADTQ-..----FDFE.HLKFIQST......G.FKGVMLDTLDKT.QGS....LLNVMALPRIEEFVSLAKMNGLLCGLAGSLTCEDIAELLPL..ATDYLGFRGALCEHA.NRV.ARLSEQRLAQV-k.................
#=GR A0A0F3IJ22_9GAMM/4-218   pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
R9SKK3_9EURY/3-231                  ...............................LLISPINHEEAVEAI..EG..GADIVDVKNPKEGSLGANFPWVIKDIRE........LTPS....................D...KLVSSTIGDVPYKP.................GTVSLASLGALKC.G.....ADYIKVGLYG.....TKNYDEAVEVMSNVVKAVK.DES....PET.IVVAAGYADAER..VGAVSPWD.IPKVARDS......G.SDLAMLDTAVKD.GKT....LFDFMSMEDLEKWVAEAKEYDLNTALAGSVKKDQIKPLYDL..HCDVVGIRGAACVDG.DRNtGHIDRTAVKEL-k.................
#=GR R9SKK3_9EURY/3-231       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0F8Y2K1_9ARCH/7-238              ...............................LLISPKTIEEAKIVI..SA..KIDFIDCKNPEEGSLGANFPWVIKKMRE........LIPN....................Ns.pQLLSAAIGDFPNLP.................GSASLAALGAAVS.G.....ADIIKVGLKG.....SKNVEEGIKLMKGVVKTVK.DYN....ENI.QVVTAGYADYIR..MDTALNFLsIPIIAAES......G.SDVAMLDTFIKD.NKN....LFDFLTLNQLVEFKKLANGFGLKIALAGKLNQTNLSKIKKI..NPDIIGVRSMVCERQ.DRNnGKIKLKLIENL-m.................
#=GR A0A0F8Y2K1_9ARCH/7-238   pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0F2SC28_9FIRM/16-244             ...............................LLVSVVNLAEAKVAF..EG..GTDVLDIKNPAEGALGAPRPGVIADICR........VYKG....................K...KPISVALGEFPGKP.................SAAALVAMGAAQF.Q.....PDYLKIAFLA.....DATRAEIVTTLQEIRLGVA.YVQ....PEEiPVVAVAYADTLP..SASWTLEE.FTTFAQDG......G.AQGCLVDTWEKN.GTS....LPNFLSRQQSAEFIANCHDRQLFCGLAGSLKPEEIGSLLTL..GPDIIGVRSAAC-GG.DRLrGEVTSQRVTGL-k.................
#=GR A0A0F2SC28_9FIRM/16-244  pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
Q0BU42_GRABC/4-225                  ...............................MLTSVTGPEEAEVAL..AG..GADIIDLKDPSIGALGAVSPDVVRHTVDavarwdaaHNHS....................G...HKVSAVTGDLPMDP.................ALIVQAAEAMVEA.G.....VHYVKIGFFE.....-GDPQKVLDALAPLSGRV-.---....---.RLVAVLFADRK-..----PDLA.ILPTLKGA......G.FYGAMLDTADKG.AGG....LLSHMKAPALLDFTRACRRIGLEPGLAGSLEEPDVPRLLLL..APAFLGFRRALT-EG.ARA.GAVTLERVRTV-r.................
#=GR Q0BU42_GRABC/4-225       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
E4RM66_HALHG/3-230                  ...............................LLISVQSISEAKKIK..RS..DFDILDIKNPNEGSLGTNFPYVIKGIRE........QFPD....................-...FPLSAAGGDLPALP.................GLASQVAFGLAHL.E.....LDYIKLGLYG.....MQSVEAATDLLREAKRAVD.MSG....AKNiKIIAAAFADFRE..ANTFSPFL.LNEVAAET......G.IDGVMIDTINKK.NKS....LFSFLKIKELKNFVEDGKKLNLITALAGSLNFNDLDKLREI..KADIIGFRGAVCKNE.DRS.AEISPEKINSL-y.................
#=GR E4RM66_HALHG/3-230       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
F6D669_METPW/3-231                  ...............................LLISPINTEEALEAV..EG..SADIIDVKNPKEGSLGANFPWVIKSIRE........LTPE....................A...MHVSATIGDVPYKP.................GTVSLAAAGAVVS.G.....ADYIKVGLYG.....TKNYDEALEVMKNVVKSVR.EFD....HDA.LVVASGYADAHR..VGAVDPME.IPRVAAES......G.ADIAMVDTAVKD.GKT....LFDFMDKDALTKFTDDTHKYGLKVALAGSVKAEQLEMLYDI..GCDIVGIRGAACVGG.DRNtGKIHRSAVSKLK..................
#=GR F6D669_METPW/3-231       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
G2DX21_9GAMM/4-219                  ...............................LLASVTDAEEAELAI..QG..GADLIDLKDPARGALGALNLTEIRHILA........QVGE....................R...RPVSATIGDLPPDA.................RATESAIRTTAAT.G.....VDLVKIGFFS.....EAHLDACLPVVADLSAKI-.---....---.AIVAVLFADRP-..TAET----.DPARFAEA......G.CAGVMLDTADKS.RGR....LLDHLDTDSLRRFVDRAKQLDLMSGLAGSLRQEDIAHLLPL..APSYLGFRGALCTSG.QRA.ERLVPERLTEI-r.................
#=GR G2DX21_9GAMM/4-219       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
Y6403_STRGG/3-233                   ...............................LLISPDGVEEALACAtaAE..HLDIVDVKKPDEGSLGANFPWVIREIRA........AVPA....................D...KPVSATVGDVPYKP.................GTVAQAALGAAVS.G.....ATYIKVGLYG.....CATPDQAIDVMRGVVRAVK.DFR....ADA.FVVASGYADAHR..IGCVNPLA.LPDIARRA......G.ADAAMLDTAIKD.GTR....LFDHVPPEGCAEFVRLAHEAGLLAALAGSVKAADLATLTRI..GTDIVGVRGAVCEGG.DRDaGRIQPRLVAAF-r.................
#=GR Y6403_STRGG/3-233        AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
MFNB_METBF/3-229                    ...............................LLISPINKEEAIIAS..RG..GADIVDVKNPKEGSLGANFPWVIRDVKG........AVNG....................R...QPISATIGDFNYKP.................GTASLAAFGAAVA.G.....ADYIKVGLYD.....IQTEDQALELITKITQAVK.DYD....STK.KVVASGYSDYKR..INSISPLL.LPSIAAKA......G.ADVVMVDTGIKD.GKS....TFEFMDEEELKKFTGLAHECGLENAIAGSLKFEDLPVLERI..GPDIIGVRGMVC-GG.DRT.NSIRQELVEKL-v.................
#=GR MFNB_METBF/3-229         AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
MFNB_ARCFU/3-230                    ...............................VLVSPMSVAEAIEAI..EG..GADIIDVKNPAEGSLGANFPWVIREISE........LAKK....................Y..gKEISATTGDMPYKP.................GTASLAALGAAVA.G.....ADYIKVGLYG.....VKNAEEAYEMMVGVVRAVK.DFD....SSK.KVVAAGYGDYYR..ISSVSPLD.LPEAVAKA......G.ADIVMVDTAIKD.GTS....LFDHMKIGDIESFVKLARDNGLMVALAGNISWNHIETLKEL..SPDIIGVRSIVC-EG.DRS.SMIKRELVVKL-m.................
#=GR MFNB_ARCFU/3-230         AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0M0BYB2_9ARCH/3-231              ...............................LLISPRDKTEAIEAI..LG..GANIIDIKNPVEGSLGANFPWIIKEVVD........IVPK....................N...VETSCTIGEMPKLP.................GSISLAARGAASL.G.....VNYIKAGLAG.....LKKIEDAIYLMTNIVKAAK.NYN....PKI.KVVITGYADAEK..IGSIDPNL.VPIIASNI......S.ADVAMIDTALKN.GKA....LFDLLDKNQIENFINSAHKLRLKAALAGSIKISDLEKVQSL..EPDILGIRGAACTNN.NRLyGKITKEKVKKI-a.................
#=GR A0A0M0BYB2_9ARCH/3-231   pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0F7N1Y6_9ACTN/3-233              ...............................LLISPDGVEEALDCA..KAaeHLDIVDVKKPDEGSLGANFPWVIREIRD........AVPA....................D...KPVSATVGDVPYKP.................GTVAQAALGAVVS.G.....ATYIKVGLYG.....CTTPDQGIEVMRAVVRAVK.DHR....PDA.LVVASGYADAHR..IGCVNPLA.VPDIAARS......G.ADAAMLDTAVKD.GTR....LFDHVLPDVCAEFVRLAHASGRLAALAGSVTQADLGPLTRI..GTDIVGVRGAVCEGG.DRNtGRIQPHLVAAF-r.................
#=GR A0A0F7N1Y6_9ACTN/3-233   pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
I1YJP7_METFJ/7-224                  ..............................w-LASVQSLAEAQSLN..AC..LPDMLDMKQPAKGALGALPLDVVSDIVR........WNAN....................R...CLTSATIGDLPMQA.................PMIESAIHQMAKT.G.....VDFVKVGLFG.....GDEQADCLQALTPFISQQN.T--....---.PVIAVMFADRQ-..----YDND.VITQIVNT......G.FRGVMIDTADKN.GQS....LLDLWSTEALTEFVQKIKSADRLCGLAGALRLGDIATLRAL..QPDYLGFRSALCPER.NRN.GSLSAALAKS--ia................
#=GR I1YJP7_METFJ/7-224       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0E3X1A5_METMT/3-227              ...............................LLVSPINTEEAMSAL..NG..GADVIDIKNPKEGSLGANFPWVIRDVKD........AIEG....................K...RPISAALGDFNFKP.................GTAALAAYGAASA.G.....ATYVKVGLYD.....VKTEEQAFEMMTGIAESVK.G--....MNV.KVVACGYSDYER..IDSIDPKL.LPAIGEKA......G.VDLVMVDTGVKD.GRS....TFEFMNEDDLIEFVNDAHSRGLETAIAGTIKFDDIPALKRI..QPTIIGVRGIVC-GG.DRS.TTIRQELVEKLK..................
#=GR A0A0E3X1A5_METMT/3-227   AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
F2KQ15_ARCVS/3-228                  ...............................VLVSPADVQEAIESI..EG..GADIIDVKNPAEGSLGANYPWVIRDIAK........VVKE....................H..gKEVSATIGDMDFKP.................GTASLAAFAVASC.G.....ANYVKVGLYG.....VRRKDEAFKLVRAVVNAVN.EFG....--S.KVVVAGYADFRR..IGSISPLE.LPEVVRNA......G.AHGVMVDTAVKD.GSR....LFDHMGVEELATFVELAHSNDLFCALAGSIQFEDIPVLKKL..GADIVGVRTAVC-EN.GRN.SKIRRELVAKL-v.................
#=GR F2KQ15_ARCVS/3-228       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
I3CHH0_9GAMM/4-220                  ...............................LLASVMNVAEADQAL..QG..GADIIDLKNPLAGALGALPSATIRAVTQ........FVNH....................R...APVSATVGDLPMQA.................EMIYRAVAKTMDD.G.....VDYVKIGFWG.....ATPALDCMKALEPLTQRGG.---....---.KLIAVLFADQQ-..----PNLA.TLFEFAQA......G.FTGVMLDTANKQ.KGN....LTHYLNNSELGFFVKQTQSLGLINGLAGSIGLANIPQLMIL..SPFYLGFRGALCVAQ.QRQ.AVLQAHAVKQI-r.................
#=GR I3CHH0_9GAMM/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D1Z2Y8_METPS/3-227                  ...............................LLVSPMNVQEAIAAE..QG..GADIIDVKNPKEGSLGANFPWVISQIKS........HISK....................-...-PLSATIGDFNFKP.................GTASLAALGAAVA.G.....AQYIKVGLYD.....IHTPEQAYELLAGVTRAVR.TFD....AEK.IVVASAYSDYER..IGSISPFE.LPAAAKRA......D.ADVVMVDTGIKD.GRS....TFEFMGSEELKKFVDLAHENKLNCAIAGSIKLKDIAFLREI..SPDIIGVRGMVC-GG.DRT.QAIRPELVAEL-k.................
#=GR D1Z2Y8_METPS/3-227       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
MFNB_METMA/3-229                    ...............................LLVSPINSEEAIIAS..IG..GADIVDVKNPKEGSLGANFPWVIREVKA........VVNG....................R...QPISATIGDFNYKP.................GTAALAALGAAVA.G.....ADYIKVGLYD.....IQTESQALELLTKITRAVK.DYN....PLK.KVVASGYSDYKR..INSISPLL.LPAVAAEA......G.VDVVMVDTGVKD.GKS....TFEFMDEKELKEFTDLAHSYGLENAIAGSLKFEDIPLLERI..GPDIIGVRGMVC-GG.DRS.TSIRQELVEKL-v.................
#=GR MFNB_METMA/3-229         AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
B1Y0Y4_LEPCP/23-247                 ..............................a-LVSVRNLAEARLAA..QA..RVGFIDLKEPNDGALGGLAVAHIAQIVRal....reVAPG....................-...VPISATIGDWPAHA................lAEIRERVRQVAAC.G.....VDHVKVGIDP....aSASGPEALMALVEELGRL-.--D....REGlPLVPVLIADNG-..---V-EPA.LLQRVCAQ......R.FFAVMLDTADKR.GGS....LLQRLGAVELAGLIAQVRAHGSLIGLAGALQLCDLPALRRL..APDFAGFRSAVC-VG.DRR.EGMDARLLAQL-v.................
#=GR B1Y0Y4_LEPCP/23-247      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
H0Q584_9RHOO/4-228                  ...............................LLASVRDRGEALAAA..AA..GADFIDLKEPRDGALGGLAIPQIRDIVA........VLRDt.................hpA...LPISATIGDHAADAlae..........idalAEIDAAVAAVAAC.D.....VDYVKVGIAG.....-GDVRVQVALLARLAQSPR.---....---.PVVPVFIADRG-..----IDLS.AVHAACRL......P.FPAVMADTEDKR.AGS....LFDCVTRAALAEFVGCVRGAGKLVGLSGALRTQHLPRLVAL..EPDFAGFRGALC-EG.SRI.GTLDPDRLRAL-r.................
#=GR H0Q584_9RHOO/4-228       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
G0A6W1_METMM/4-219                  ...............................MLASVNSLDEALLIQ..SF..SVDIVDLKQPAQGALGALSVSEVAEIVA........NLSG....................R...NVISATVGDLPMQP.................DLLFTAVQAMAST.G.....VDYVKIGFFP.....GGDWQACIDSLATLARTY-.---....---.RLIAVLFADTG-..----PDVG.IINALRKA......G.FAGVMLDTMDKT.LGS....LTQLMTWSELAGFTDAAKAAGLLTGLAGSLTQHDIPALLSL..QADYLGFRGALCRQH.CRT.AQLDADRIV---wir...............
#=GR G0A6W1_METMM/4-219       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
G8XHM5_STREN/8-238                  ...............................LLISPDSVEEALDCA..KAaeHLDIVDVKKPDEGSLGANYPWVIREIRD........AIPA....................D...KPVSATVGDVPYKP.................GTVAQAALGAVVS.G.....ATYIKVGLYG.....CTTPDQVVEVMRGVVRAVK.DHR....PDA.LVVASGYADAHR..IGCVNPLA.IPGVAQRS......G.CDAAMLDTAVKD.GTR....LFDHVPPDVCGEFVRLAHEGGLLAALAGSVKAEDLGALTRI..GTDIVGVRGAVCEGG.DRNaGRIQPHLVAAF-r.................
#=GR G8XHM5_STREN/8-238       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
Q7URG4_RHOBA/32-257                 ...............................LLVSVRDLGEARVAV..SG..GVDILDFKEPSRGALAACDPCVWKSAVSefv..dgaPADC....................T...VRLSAALGESDTGA.................DLSSLVPPE----.-.....FSFAKVGPSG.....CSTAKKLMELWESVRLPQS.V--....---.ELVPVAYADHLV..ADTISVER.VLDIVIES......G.RHRLLIDTFGKD.GRT....LTDHLSIDRLRALANMASEHSVWIALAGSLRLPEMRSLMSEgvRPDCWGVRGDVCDQR.ERT.GRINLHKVTAW-r.................
#=GR Q7URG4_RHOBA/32-257      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0F7IEG2_9EURY/3-230              ...............................VLVSPMSIEEAVESL..KG..GADIIDVKNPAEGSLGANFPWVIRQVKE........LVEK....................E..gKLLSATVGDLDFKP.................GTASLAALGAAYA.G.....ADYIKVGLYG.....VKTAEQVYEMMSKVVRAVK.DFN....PSA.MVVAAAYADHSR..VGAVSPLE.IAEPAYRA......G.CDGIMVDTAIKD.GKN....LFEFMDAEALERFISSAHERGMFCALAGSLSWNHMDILKSL..EPDIIGVRTMVC-EN.GRN.SMIRSELVAKL-m.................
#=GR A0A0F7IEG2_9EURY/3-230   AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
C0N597_9GAMM/4-220                  ..............................w-LASVQSLAEAQTLL..SC..LPDILDLKNPSQGALGALSVYDVETIVQ........WLDG....................R...CLTSATVGDLPMKA.................PVIAEAVTAMASS.G.....VDYVKVGLFA.....DKNLQSCLLELKTTLAKLK.T--....---.PTIAVVFADQK-..----TELD.L-SLIKQA......G.FAGVMVDTATKD.GLR....LFDHWSEQQLRTFVSRAHELSMLCGLAGALAIDDITLLQPF..NADYLGFRSALCDKR.QRT.QALQLSL-----amria.............
#=GR C0N597_9GAMM/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0B617_METTP/5-231                  ...............................LLVSPMDLEEAVAAL..DG..GADIIDVKNPREGSLGANFPWAIRSVVE........LVAG....................R...TPVSATIGDLPFKP.................GTASLAALGAAVS.G.....ADYIKAGLLG.....VSEPEEAIELLRPIVRSVR.DYD....SRR.KIVAAAYSDFRR..AGSLPPLV.LPEIAAEC......G.ADVVMVDTAIKD.GRS....TLEFMSVEELKHFVESAHDLGMEAALAGNLGVRDLEAIRAA..SPDILGVRGAVC-GG.DRN.SRIRAELVRSL-k.................
#=GR A0B617_METTP/5-231       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
F8J8T1_HYPSM/12-227                 ..............................f-LASVTTAGEAEIAL..AG..GADIIDCKDPAAGALGALSAATVREIVA........GVGG....................R...LPVSATIGDLPPEP.................DVLTNAASDMAAT.G.....VDIVKIGFFG.....SEDPRRAIAALGAAHARS-.---....--T.KLVAVLMADQN-..----PDFA.LVADLAAA......G.FSGVMVDTADKS.AGR....LTTVLSAARLMEFVRLARDNRLFVGLAGSLRERDIDVLAGL..GPDLLGFRGALC-AQ.GRV.SAIELSRVVSV-r.................
#=GR F8J8T1_HYPSM/12-227      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
Q7NR24_CHRVO/3-231                  ...............................VLISPISTAEAVVAW..EC..GTNIIDIKNINEGSLGASFPWIIREVIA........RIND....................P..kVVFSATLGDLPHKP.................GTASLAALGAVSS.G.....VKYVKAGLHG.....SKDVAEGVELMSAVVRTCK.DFD....PSV.TVVTAGYADYQR..FGGLSPQQ.LVEIAAQS......K.SDMVMVDTYIKD.GKS....LFDALNEQQLTEFVQQAHAKGLKVALAGSVRAEHLELLARI..GADVVGVRGAVCSGY.DRG.TTIDPLKAEQ--fi................
#=GR Q7NR24_CHRVO/3-231       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
B8ILG5_METNO/17-225                 ...............................LLVSVRDADEAALAR..AE..GADLVDAKDPARGALGALPADSVRAIVA........AAAG....................-...GLTSAVAGEPADAA................eAAAMLAALG--GT.G.....ADFLKIALPP.....G---LPV----SELTLPAG.P--....---.PVIAVLFAEDR-..----PSPE.MMPALAAA......G.FRGAMIDTRGKD.GRR....LTDHLALPHLAAFAASCRRLGLLSGLAGSLALDDIPVLLPL..APGYLGFRGGLCAAS.DRR.TSLDPARIAE--aa................
#=GR B8ILG5_METNO/17-225      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
G8AVE2_AZOBR/4-224                  ...............................LLASVASLAELTLAA..RG..DADILDLKDPKTGALGAWPLDGIVRAVDt.....arQWPV....................R...APLSATVGDLPMAP.................AIVAGRVVETWAC.G.....VDYVKIGLFP.....SGDPAGCVKALAPDTR-RG.---....--A.RIVAVLFADLW-..---NDPGT.LLPDIARA......G.FAGAMLDTAGKG.SGG....LLRHKTKDELARFLAQARDHGLLTGLAGSLRLDDIPPLLPL..APDYLGFRTALCAGA.DRG.GVLDPAALAAV-r.................
#=GR G8AVE2_AZOBR/4-224       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
Q0W6B9_METAR/3-227                  ...............................LLVSPINIEEAIIAD..TG..GADIVDVKNPKEGSLGANFPWVIQAVKA........RVTK....................-...-PVSATIGDFNYKP.................GTASLAALGAAAA.G.....AEYVKVGLYD.....IQTEAQAYEVLAGIVKAVK.TYD....RNR.IVVASGYSDYAR..IGSIPALK.LPAVAQRA......G.CDVVMVDTGIKD.GKS....TFEFMGQPELQAFVDAAHAEGLQCALAGSIKFKDIPVLQEI..KPDIIGVRGLVC-GG.DRT.EAIRADLIEKLR..................
#=GR Q0W6B9_METAR/3-227       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A0K8P5D4_9BURK/31-254             ...............................LLVSVRDLAEARAVA..AA..GIDFVDLKDPSDGALGALPLPLLGAIVQ........ALRAg.................gtA...PRLSATTGDLPPEA................rEAVRTRALATAAA.G.....VDLVKVGIGP.....-GPAAAACALLDRL-AVLP.---....--A.AIVPVLIADAG-..IDPAVSAH.ALALRRHH......GcFPALMLDTAGKG.RGS....LLQRRPTAELRDWVAAVRASGALAGLAGALRADELPALRAL..GADYAGFRSAVC-AG.DRA.GALDPARLAAL-l.................
#=GR A0A0K8P5D4_9BURK/31-254  pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
F4BY02_METCG/3-229                  ...............................LLVSPMNMEEAHAAL..AG..GADILDVKNPKEGSLGANFPWVIRSVAD........LARG....................K...VPVSATIGDMEFKP.................GTASLAALGAASS.G.....ADYVKAGLLG.....VKTCDQAEEMLKAIVRAVK.DLD....PKK.KVVASGYSDYLR..VGSISPML.LPAAASEA......G.ADVVMVDTAIKD.GKP....TFDFMGEKDLADFIELGHSNDLEVALAGSIGFPHLETLLRL..QPDIIGVRGIVC-GG.DRR.SAVKEELVVKV-k.................
#=GR F4BY02_METCG/3-229       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
I9W7D2_9RALS/4-220                  ..............................v-LTSVRNIEEARDAA..RA..GADMIDLKEPRAGALGALPTNIVREVVD........VIRT....................EhpaLLLSATVGDLEAAA................lAEMEAMVEAIGAC.G.....VDYVKVGIAP.....GMHGHAALDHLATLP----.---....--W.RIVPVLLCDDG-..----LDMA.LVEHACTQ......A.FPAVMADTARKQ.AGS....LFDCVPQGDLRALVEQVRGSGLQVGLAGALQLDDLPRLRGL..APDFAGFRSALC-VA.GRD.SRLDPARVLQV-r.................
#=GR I9W7D2_9RALS/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
G2P3P4_STRVO/10-240                 ...............................LLISPDSVDEALDCA..KAaeHLDIVDVKKPDEGSLGANFPWVIREIRD........AVPA....................D...KPVSATVGDVPYKP.................GTVAQAALGAAVS.G.....ATYIKVGLYG.....CTTPEQAIDVMRGVVRAVK.DYR....PDA.FVVASGYADAHR..IGCVNPLA.LPDIARRS......G.SDAAMLDTAIKD.GTR....LFDHVPPDVCAEFVRLAHEADLLAALAGSVKVGDLGELTGI..GTDIVGVRGAVCEGG.DRNaGRIQPRLVAAF-k.................
#=GR G2P3P4_STRVO/10-240      pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
B9TAC8_RICCO/1-217                  ...............................MLASVTSIAEAEVVL..AA..NVDIIDLKNPAQGALGALPGDVIREVVR........FVNG....................R...KPVSATVGDLPMVP.................EILAEAVHQTAAS.G.....VDFVKVGLFG.....RSDHQACIQALQSQTLQG-.---....--I.RVVAVLFADQS-..----PDFS.ILQALADA......G.FYGAMIDTAGKT.QGG....LRKWLGTASLQSFVDTAGCLGLFTGLAGALRMDDIIPLLTL..KPDYLGFRGALCGNH.HRE.SELDPMRVSAI-s.................
#=GR B9TAC8_RICCO/1-217       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
D3E3E8_METRM/3-231                  ...............................LLISPINHEEAVESI..EG..GADIVDVKNPKEGSLGANFPWVIKDIRE........LTPK....................D...MLVSATLGDVPYKP.................GTVSLAAMGALVS.G.....ADYIKVGLYG.....PSNYEEGVEVMKGVVKAVK.DTN....PDA.TVVASGYADAHR..VGAVSPWD.IPKVAKDS......G.ADIAMLDTAVKD.GHT....LFDYLDIDDCRKFTEEAHSYGLKVALAGSVKKDQLKPLYDV..GCDVVGVRGAACVGG.DRNtGHIDRTAVAEL-k.................
#=GR D3E3E8_METRM/3-231       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
A0A059VV05_STRA9/10-240             ...............................LLISPDGVEEALTCA..KAaeHLDIVDVKKPDEGSLGANFPWVIREIRA........AVPA....................D...KPVSATVGDVPFKP.................GTVAQAALGAVVS.G.....ATYIKVGLYG.....CTTPEQAIEVMRGVVRAVK.DHR....PDA.CVVASGYADAHR..IGCVNPLA.LPDVARRS......G.ADAAMLDTAIKD.GTR....LFDHVPPEVCAEFVRLAHQAGLLAALAGSVGRADLGALTRI..GTDIVGVRGAVCEGG.DRNaGRIQPHLVAAF-r.................
#=GR A0A059VV05_STRA9/10-240  pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
E3GXG6_METFV/3-231                  ...............................LLVSPINTKEAKEAI..EG..GADIIDVKNPKEGSLGANFPWVIKSIKE........IIPK....................D...KLLSATVGDIDYKP.................GTVSLAVLGAVTS.G.....ADYVKIGLYG.....TKNYEQALEVMKNAVKTVE.YSE....SEA.FVVAAGYGDAKR..VNSVDPME.IPNIAADA......D.ADVAMLDTAIKD.GKC....LLDFLNLNELAEFVENSHDHGLKCALAGSLKKEHVKLLHEI..GCDIVGIRGAACIGG.DRNkGYIHRSAVSEL-k.................
#=GR E3GXG6_METFV/3-231       AS    ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
Q609J1_METCA/4-220                  ...............................MLASVRNLTEARIAL..EA..GVDIVDLKAPEYGSLGALPADEVGRIVA........EMEG....................T...VPVSATIGDLPLEP.................DPICRAVREMADT.G.....VDYVKIGMFR.....GGDWSSTLAALAQLA-SHG.T--....---.RLVAVLFADNL-..----PDFD.WIARLKKA......G.FAGAMLDTQDKD.SGP....LTEILDRAVLERFVGETRAQSLLCGLAGSLRSQDVPGLLSL..EPDYLGFRGALCHGA.RRA.AGIDPEALADV-r.................
#=GR Q609J1_METCA/4-220       pAS   ...........................................................*...............................................................................................................*.................................................................................................................................................................................................
#=GC SS_cons                        ...............................EEE--SSHHHHHHHH..HH..T-SEEEE--GGG-TT----HHHHHHHHH........HS-T....................T...SEEEEEEEEE-S-H.................HHHHHHHHHHHHT.T.....-SEEEEEE-S.....--SHHHHHHHHHHHHHHHH.HH-....TTS.EEEEEEETTGGG..TT---GGG.HHHHHHHH......T.-SEEEEE-SS-S.S--....HHHHS-HHHHHHHHHHHHHTT-EEEE-SS--GGGHHHHHHT..T-SEEEESGGGBTTS.STTTSSB-HHHHHHHH..................
#=GC seq_cons                       ...............................LLlSspsh-EAhtuh..pu..GADIlDlKpPs-GuLGAs.PhlI+pIhp........hlsu....................c...tslSATlGDlshcP.................usluhAAhusAss.G.....sDYlKlGLas.....sps.ppsl-hhpslspslp.t........t.tVVAshaADtp.......ssht.lsshuscu......G.hcusMlDTAhKD.Gps....Lh-ahs.spLscFlptu+stGLhsuLAGSL+hpDlshLtpl..sPDllGhRGAlC.sG.cRs.uplcschVtph.t.................
//
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