GenomeNet

Database: Pfam
Entry: DUF746
LinkDB: DUF746
Original site: DUF746 
#=GF ID   DUF746
#=GF AC   PF05344.6
#=GF DE   Domain of Unknown Function (DUF746)
#=GF AU   Yeats C, Eberhardt R
#=GF SE   Yeats C
#=GF GA   23.70 23.70;
#=GF TC   23.80 31.10;
#=GF NC   23.00 23.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   21348639
#=GF RT   Ab Initio Modeling Led Annotation Suggests Nucleic Acid Binding
#=GF RT   Function for Many DUFs.
#=GF RA   Rigden DJ;
#=GF RL   OMICS 2011;0:0-0.
#=GF DR   INTERPRO; IPR008008;
#=GF CC   This is a short conserved region found in some transposons.
#=GF CC   Structural modelling suggests this domain may bind nucleic acids
#=GF CC   [1].
#=GF SQ   78
#=GS B5S3H3_RALSL/150-214  AC B5S3H3.1
#=GS B2HAV3_BURPE/93-157   AC B2HAV3.1
#=GS A5J2T5_BURML/99-163   AC A5J2T5.1
#=GS C4IA00_BURPE/25-89    AC C4IA00.1
#=GS B9JG85_AGRRK/48-111   AC B9JG85.1
#=GS Q8Y104_RALSO/360-424  AC Q8Y104.1
#=GS H1S5I8_9BURK/120-184  AC H1S5I8.1
#=GS C6BQ12_RALP1/95-159   AC C6BQ12.1
#=GS A8KDX2_BURPE/360-424  AC A8KDX2.1
#=GS C5ZQC0_BURPE/20-84    AC C5ZQC0.1
#=GS C5NGW3_BURML/168-232  AC C5NGW3.1
#=GS A5TGF1_BURML/59-123   AC A5TGF1.1
#=GS B7CHX2_BURPE/120-183  AC B7CHX2.1
#=GS A5XK11_BURML/99-163   AC A5XK11.1
#=GS A5XK11_BURML/247-311  AC A5XK11.1
#=GS A3P918_BURP0/20-84    AC A3P918.1
#=GS G3A9F6_9RALS/101-165  AC G3A9F6.1
#=GS F6G6P7_RALS8/110-174  AC F6G6P7.1
#=GS C4AXN5_BURML/168-232  AC C4AXN5.1
#=GS B7CQ28_BURPE/1-63     AC B7CQ28.1
#=GS Q63IL9_BURPS/93-157   AC Q63IL9.1
#=GS C4AXN5_BURML/20-84    AC C4AXN5.1
#=GS H5WDF7_RALSL/110-174  AC H5WDF7.1
#=GS A3P945_BURP0/354-418  AC A3P945.1
#=GS G3A9F6_9RALS/360-424  AC G3A9F6.1
#=GS H5WFI6_RALSL/115-179  AC H5WFI6.1
#=GS C5ZQ94_BURPE/255-319  AC C5ZQ94.1
#=GS B9TBN6_RICCO/7-59     AC B9TBN6.1
#=GS Q3JJA5_BURP1/360-424  AC Q3JJA5.1
#=GS Q8XUK9_RALSO/242-306  AC Q8XUK9.1
#=GS Q3JJA5_BURP1/251-315  AC Q3JJA5.1
#=GS H5WFI6_RALSL/363-425  AC H5WFI6.1
#=GS A9JYR1_BURML/247-311  AC A9JYR1.1
#=GS A1UUK5_BURMS/59-123   AC A1UUK5.1
#=GS A5J2T5_BURML/247-311  AC A5J2T5.1
#=GS Q63II2_BURPS/77-141   AC Q63II2.1
#=GS Q62C59_BURMA/99-163   AC Q62C59.1
#=GS A3RUB3_RALSL/398-460  AC A3RUB3.1
#=GS Q62C59_BURMA/247-311  AC Q62C59.1
#=GS Q3JJC8_BURP1/93-157   AC Q3JJC8.1
#=GS A8KDX2_BURPE/251-315  AC A8KDX2.1
#=GS B5S3H3_RALSL/398-460  AC B5S3H3.1
#=GS A3MDR1_BURM7/59-123   AC A3MDR1.1
#=GS A8KDZ9_BURPE/20-84    AC A8KDZ9.1
#=GS A3P945_BURP0/245-309  AC A3P945.1
#=GS C6BQ12_RALP1/340-404  AC C6BQ12.1
#=GS C4I9U9_BURPE/20-84    AC C4I9U9.1
#=GS Q8Y104_RALSO/101-165  AC Q8Y104.1
#=GS A2RWX9_BURM9/207-271  AC A2RWX9.1
#=GS B1H9P3_BURPE/360-424  AC B1H9P3.1
#=GS A3MDR1_BURM7/207-271  AC A3MDR1.1
#=GS C4IA00_BURPE/134-198  AC C4IA00.1
#=GS B2HAV3_BURPE/241-305  AC B2HAV3.1
#=GS A9JYR1_BURML/99-163   AC A9JYR1.1
#=GS C6UAE7_BURPE/364-428  AC C6UAE7.1
#=GS A2RWX9_BURM9/59-123   AC A2RWX9.1
#=GS C6UAC1_BURPE/20-84    AC C6UAC1.1
#=GS H5WDF7_RALSL/369-433  AC H5WDF7.1
#=GS B5SAY3_RALSL/397-460  AC B5SAY3.1
#=GS C0XYH1_BURPE/5-69     AC C0XYH1.1
#=GS C5NGW3_BURML/20-84    AC C5NGW3.1
#=GS A4LGH5_BURPE/1-37     AC A4LGH5.1
#=GS B1H9P3_BURPE/251-315  AC B1H9P3.1
#=GS B1H9H2_BURPE/20-84    AC B1H9H2.1
#=GS C5ZQ94_BURPE/364-428  AC C5ZQ94.1
#=GS C6UAE7_BURPE/255-319  AC C6UAE7.1
#=GS F6G6P7_RALS8/369-433  AC F6G6P7.1
#=GS B7CHX2_BURPE/367-427  AC B7CHX2.1
#=GS B2JXE0_BURP8/107-171  AC B2JXE0.1
#=GS A1UUK5_BURMS/207-271  AC A1UUK5.1
#=GS B5SAY3_RALSL/150-213  AC B5SAY3.1
#=GS Q8XUK9_RALSO/94-158   AC Q8XUK9.1
#=GS B2JXE0_BURP8/254-318  AC B2JXE0.1
#=GS A5TGF1_BURML/207-271  AC A5TGF1.1
#=GS C0XYH2_BURPE/19-60    AC C0XYH2.1
#=GS A3RUB3_RALSL/150-213  AC A3RUB3.1
#=GS Q63II2_BURPS/1-32     AC Q63II2.1
#=GS Q63IL9_BURPS/241-305  AC Q63IL9.1
B5S3H3_RALSL/150-214             ..akga----AMIPLLSRQMSLDQAGKRLGRTKKAVLSWLLAFRRWLLELDPSGQLEARVRLGVRVA----phan..
B2HAV3_BURPE/93-157              .....k-KRDLFVSLLSQPISCLEAGKQMGSLPDDIGQRVKVWRAWLLQLDPSGQWERRVRLGGRPTELNP......
A5J2T5_BURML/99-163              ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGERVKVWRAWLLQLDPSGQWERRIRLGGRPTELNP......
C4IA00_BURPE/25-89               ......KKLDLFVSLLSHPISCVDAGEQMGSLSTDIGKRVTAWRAWLLELDPSGKWERRVRLSHRPPHCPN......
B9JG85_AGRRK/48-111              .....r-KLELFVRLLSQQRPITDAAEMIDVKVVTVIRWVKRMRQWIPELDPSGYWEARVRLGR-------hdalsr
Q8Y104_RALSO/360-424             .....d-ALPHFIRLLSQQRPLHDAIDALKLDERIAKQWVGKFRSWLLQLDPSGHYEAMVRLGLKPAAP--il....
H1S5I8_9BURK/120-184             .....d-KAEAFFNLASQQVSVAEAARRLGIKSETVRHWSIQTRLWLLKLDRQGDWERRVQLGVRYA----vlpa..
C6BQ12_RALP1/95-159              ...ekg---TAMIPLLSRQMSLLQARKRLGRTQKAMLTWLLAFRKYLLELDPTGRWEAKVRLGVRIA----pqaq..
A8KDX2_BURPE/360-424             ......ERMRLVIRRLSLPLLVMQVADLVGTSHGMVRKWHSMFTDFADRLEPSGSLSARIRLRSNSANAPN......
C5ZQC0_BURPE/20-84               ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGQRVKVWRAWLLQLDPSGQWERRVRLGGRPTELNP......
C5NGW3_BURML/168-232             ......ERMRLFIRHLSLPLSVMQAADLVGTSHGMIHKWLRMFIEFADQLEPSGSLSTRIQLGVEPTETTP......
A5TGF1_BURML/59-123              ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGERVKVWRAWLLQLDPSGQWERRIRLGGRPTELNP......
B7CHX2_BURPE/120-183             ...akg---TEMIPLLSRQMSLLQAGERLGRTQKAVLSWLLAFRRYLLELDPSGRWEARVRLGVRVA----pra...
A5XK11_BURML/99-163              ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGERVKVWRAWLLQLDPSGQWERRIRLGGRPTELNP......
A5XK11_BURML/247-311             ......ERMRLFIRHLSLPLSVMQAADLVGTSHGMIHKWLRMFIEFADQLEPSGSLSTRIQLGVEPTETTP......
A3P918_BURP0/20-84               ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGQRVKVWRAWLLQLDPSGQWERRVRLGGRPTELNP......
G3A9F6_9RALS/101-165             .....g-KMPAFIRLLSQQISLEEASFRLGLDFECISNWLARFRQLILLHDPSGQWESRVRLGIKFQFS--gt....
F6G6P7_RALS8/110-174             .....g-KMPAFIRLLSQQISLEEASFRLGLDVECISNWLARFRQLILLDDPSGQWESRVRLGIKFQFS--gt....
C4AXN5_BURML/168-232             ......ERMRLFIRHLSLPLSVMQAADLVGTSHGMIHKWLRMFIEFADQLEPSGSLSTRIQLGVEPTETTP......
B7CQ28_BURPE/1-63                ......--MRLVIRRLSLSLLVMQVADLVGTSHGMVRKWHSMFTDFADRLEPSGSLSARIRLRSNSANAPN......
Q63IL9_BURPS/93-157              ......KKLDLFVFLLSQPISCLEAGKQMGSLPDDIGQRVKVWRAWLLQLDPSGQWERRVRLGGRPTELNP......
C4AXN5_BURML/20-84               ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGERVKVWRAWLLQLDPSGQWERRIRLGGRPTELNP......
H5WDF7_RALSL/110-174             .....g-KMPAFIRLLSQQISLEEASFRLGLDVECISNWLARFRQLILLHDPSGQWESRVRLGIKFQFA--gt....
A3P945_BURP0/354-418             ......ERMRLVIRRLSLPLLVMQVADLVGTSHGMVRKWHSMFTDFADRLEPSGSLSARIRLRSNSANAPN......
G3A9F6_9RALS/360-424             .....d-ALPGFVRLLSQQRPLSDAVDQLKLDERIARQWVDKFRVWLLQLDPSGHYEAMVRLGLKPAAP--il....
H5WFI6_RALSL/115-179             ..akga----AMIPLLSRQMSLDQAGKRLGRTKKAVLSWLLAFRRWLLELDPSGQLEARVRLGVRVA----phan..
C5ZQ94_BURPE/255-319             ......KKLDLFVSLLSHPISCVDAGEQMGSLSTDIGKRVTAWRAWLLELDPSGKWERRVRLSHRPPHCPN......
B9TBN6_RICCO/7-59                ......DKQRELIRYLGLPLGVTQVAEILSTDPLSIRRWIRSFSRRCAQLDPSGDW---------------lag...
Q3JJA5_BURP1/360-424             ......ERMRLVIRRLSLPLLVMQVADLVGTSHGMVRKWHSMFTDFADRLEPSGSLSARIRLRSNSANAPN......
Q8XUK9_RALSO/242-306             ......ERQRALIRYLGLPLSITQLAEIVGGDHGNVARLIREFRERCDQLDPTGQLSHRIRAGARPAEDTP......
Q3JJA5_BURP1/251-315             ......KKLDLFVSLLSHPISCVDAGEQMGSLSTDIGKRVTAWRAWLLELDPSGKWERRVRLSHRPPHCPN......
H5WFI6_RALSL/363-425             ..yasr-----FVPMLGWHETGAGAARELGIAVGTLHTWVRSWRQWLLVLDPTATMEGRVMLALRTQK---pa....
A9JYR1_BURML/247-311             ......ERMRLFIRHLSLPLSVMQAADLVGTSHGMIHKWLRMFIEFADQLEPSGSLSTRIQLGVEPTETTP......
A1UUK5_BURMS/59-123              ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGERVKVWRAWLLQLDPSGQWERRIRLGGRPTELNP......
A5J2T5_BURML/247-311             ......ERMRLFIRHLSLPLSVMQAADLVGTSHGMIHKWLRMFIEFADQLEPSGSLSTRIQLGVEPTETTP......
Q63II2_BURPS/77-141              ......ERMRLVIRRLSLPLLVMQVADLVGTSHGMVRKWHSMFTDFADRLEPSGSLSARIRLRSNSANAPN......
Q62C59_BURMA/99-163              ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGERVKVWRAWLLQLDPSGQWERRIRLGGRPTELNP......
A3RUB3_RALSL/398-460             ...yal----HFVPMLGWHETGAGAARELGIAVGTLHTWVRSWRQWLLVLDPTATMEGRVVLALRTQK---pa....
Q62C59_BURMA/247-311             ......ERMRLFIRHLSLPLSVMQAADLVGTSHGMIHKWLRMFIEFADQLEPSGSLSTRIQLGVEPTETTP......
Q3JJC8_BURP1/93-157              ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGQRVKVWRAWLLQLDPSGQWERRVRLSGRPTELNP......
A8KDX2_BURPE/251-315             ......KKLDLFVSLLSHPISCVDAGEQMGSLSTDIGKRVTAWRAWLLELDPSGKWERRVRLSHRPPHCPN......
B5S3H3_RALSL/398-460             ..yasr-----FVPMLGWHETGAGAARELGIAMGTLHTWVRSWRQWLLVLDPTATMEGRVVLALRTQK---pa....
A3MDR1_BURM7/59-123              ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGERVKVWRAWLLQLDPSGQWERRIRLGGRPTELNP......
A8KDZ9_BURPE/20-84               ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGQRVKVWRAWLLQLDPSGQWERRVRLSGRPTELNP......
A3P945_BURP0/245-309             ......KKLDLFVSLLSHPISCVDAGEQMGSLSTDIGKRVTAWRAWLLELDPSGKWERRVRLSHRPPHCPN......
C6BQ12_RALP1/340-404             ....el--ARRFVPMLGWRNTVDVAAQALGVDASVVREWVPTWRKWLLLLDPSGTMEPRVRLDMP------vaepaa
C4I9U9_BURPE/20-84               ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGQRVKVWRAWLLQLDPSGQWERRVRLGGRPTELNP......
Q8Y104_RALSO/101-165             .....g-KMPAFIRLLSQQISLEEASFRLGLDVECISNWLARFRQLILLHDPSGQWESRVRLGIKFQFS--gt....
A2RWX9_BURM9/207-271             ......ERMRLFIRHLSLPLSVMQAADLVGTSHGMIHKWLRMFIEFADQLEPSGSLSTRIQLGVEPTETTP......
B1H9P3_BURPE/360-424             ......ERMRLVIRRLSLPLLVMQVADLVGTSHGMVRKWHSMFTDFADRLEPSGSLSARIRLRSNSANAPN......
A3MDR1_BURM7/207-271             ......ERMRLFIRHLSLPLSVMQAADLVGTSHGMIHKWLRMFIEFADQLEPSGSLSTRIQLGVEPTETTP......
C4IA00_BURPE/134-198             ......ERMRLVIRRLSLPLLVMQVADLVGTSHGMVRKWHSMFTDFADRLEPSGSLSARIRLRSNSANAPN......
B2HAV3_BURPE/241-305             ......ERMRLFIRHLSLPLSVMQAADLVGTSHGIIHKWLRMFIEFADQLEPSGSLSARIQLGVEPTETTP......
A9JYR1_BURML/99-163              ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGERVKVWRAWLLQLDPSGQWERRIRLGGRPTELNP......
C6UAE7_BURPE/364-428             ......ERMRLVIRRLSLPLLVMQVADLVGTSHGMVRKWHSMFTDFADRLEPSGSLSARIRLRSNSANAPN......
A2RWX9_BURM9/59-123              ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGERVKVWRAWLLQLDPSGQWERRIRLGGRPTELNP......
C6UAC1_BURPE/20-84               ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGQRVKVWRAWLLQLDPSGQWERRVRLSGRPTELNP......
H5WDF7_RALSL/369-433             .....d-ALPGFIRLLSQQRPLSDASDALRLDERVTQQWVRKFRSWLLQLDPSGHYEAMVRLGLKPAAPT-l.....
B5SAY3_RALSL/397-460             ...aya---SHFVPMLGWHETGAGAARELGIAVGTLHTWVRSWRQWLLVLDPTATMEGRVVLALRTQK---pa....
C0XYH1_BURPE/5-69                ......ERMRLVIRRLSLPLLVMQVADLVGTSHGMVRKWHSMFTDFADRLEPSGSLSARIRLRSNSANAPN......
C5NGW3_BURML/20-84               ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGERVKVWRAWLLQLDPSGQWERRIRLGGRPTELNP......
A4LGH5_BURPE/1-37                ......----------------------------MVRKWHSMFTDFADRLEPSGSLSARIRLRSNSANAPN......
B1H9P3_BURPE/251-315             ......KKLDLFVSLLSHPISCVDAGEQMGSLSTDIGKRVTAWRAWLLELDPSGKWERRVRLSHRPPHCPN......
B1H9H2_BURPE/20-84               ......KKLDLFVSLLSQPISCLEAGKQMGSLPDDIGQRVKVWRAWLLQLDPSGQWERRVRLGGRPTELNP......
C5ZQ94_BURPE/364-428             ......ERMRLVIRRLSLPLLVMQVADLVGTSHGMVRKWHSMFTDFADRLEPSGSLSARIRLRSNSANAPN......
C6UAE7_BURPE/255-319             ......KKLDLFVSLLSHPISCVDAGEQMGSLSTDIGKRVTAWRAWLLELDPSGKWERRVRLSHRPPHCPN......
F6G6P7_RALS8/369-433             ....da--LSGFIRLLSQQRPLRDAIDALKLDERSAKQWVGKFRSWLLQLDPSGHYEAMVRLGLKPAAP--il....
B7CHX2_BURPE/367-427             khalql------ARMLGWRETNRAAAIELGIDPTMAHRWVYGMRQWLLKLDPSGRMEERVKLGV-------gre...
B2JXE0_BURP8/107-171             ......QQAGELIALLPQEISCAEAARQLGVMEHTVLETVRLVRRWLLELDASGHYEPGVRLGGRFTAAQP......
A1UUK5_BURMS/207-271             ......ERMRLFIRHLSLPLSVMQAADLVGTSHGMIHKWLRMFIEFADQLEPSGSLSTRIQLGVEPTETTP......
B5SAY3_RALSL/150-213             ..akga----AMIPLLSRQMSLDQAGKRLGRTKKAVLSWLLAFRRWLLELDPSGQLEARVRLGVRVA----pha...
Q8XUK9_RALSO/94-158              .....r-SAEELITMLPQAIGCPEAARRLGVMERTIRNTVRMFRRWVLELDPSGHHERHIRLGGRFTAVR-d.....
B2JXE0_BURP8/254-318             .....a-RQRELIRYLGLPLPLAQLADMIDTDPAITARLVDEFRTRCAQLDPSGRLASRIRACVRPATDTP......
A5TGF1_BURML/207-271             ......ERMRLFIRHLSLPLSVMQAADLVGTSHGMIHKWLRMFIEFADQLEPSGSLSTRIQLGVEPTETTP......
C0XYH2_BURPE/19-60               ......KKLDLFVSLLSHPISCVDAGEQMGSLSTDIGKRVTAWRAWLL-----------------------......
A3RUB3_RALSL/150-213             ..akga----AMIPLLSRQMSLDQAGKRLGRTKKAVLSWLLAFRRWLLELDPSGQLEARVRLGVRVA----pha...
Q63II2_BURPS/1-32                .....m----------------------------------TAWRAWLLELDPSGKWERRVRLSHRPPHCPN......
Q63IL9_BURPS/241-305             ......ERMRLFIRHLSLPLSVMQAADLVGTSHGIIHKWLRMFIEFADQLEPSGSLSARIQLGVEPTETTP......
#=GC seq_cons                    ......c+hcLFlphLS.PlSshpAuctlGot.ssltchlphaRpalLpLDPSGphEtRlRLGs+ssphss......
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