GenomeNet

Database: Pfam
Entry: DUF905
LinkDB: DUF905
Original site: DUF905 
#=GF ID   DUF905
#=GF AC   PF06006.10
#=GF DE   Bacterial protein of unknown function (DUF905)
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_7072 (release 9.0)
#=GF GA   22.30 22.30;
#=GF TC   31.90 55.00;
#=GF NC   18.70 18.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   19455708
#=GF RT   NMR structure of protein YvyC from Bacillus subtilis reveals
#=GF RT   unexpected structural similarity between two PFAM families.
#=GF RA   Eletsky A, Sukumaran DK, Xiao R, Acton TB, Rost B, Montelione
#=GF RA   GT, Szyperski T;
#=GF RL   Proteins. 2009;76:1037-1041.
#=GF DR   INTERPRO; IPR009253;
#=GF CC   This family consists of several short hypothetical
#=GF CC   Enterobacteria proteins of unknown function. Structural analysis
#=GF CC   of the surface features of the protein YvyC has revealed a
#=GF CC   single cluster of highly conserved residues on the surface.
#=GF CC   Additionally, these residues fall into two groups which lie
#=GF CC   within the two largest of the three cavities identified over the
#=GF CC   surface. The conclusion from this is that these two cavities
#=GF CC   with, Leu 58, Glu 75, Ile 82, and Glu 83 and Pro 86, conserved,
#=GF CC   are likely to be important for the molecular function and
#=GF CC   reflect the cavities found on the surface of the FlaG proteins
#=GF CC   in Pfam:PF03646.
#=GF SQ   14
#=GS A0A0A1BA84_9ENTR/6-77   AC A0A0A1BA84.1
#=GS YUBL_YERPE/6-74         AC Q7ARC3.1
#=GS A6TIR7_KLEP7/10-78      AC A6TIR7.1
#=GS V5CQX1_ENTCL/5-73       AC V5CQX1.1
#=GS YPJI_ECOLI/15-85        AC P58095.1
#=GS YUBL_SALTY/10-78        AC Q93GP6.1
#=GS A0A0L0GQB8_9ENTR/7-76   AC A0A0L0GQB8.1
#=GS J2IK30_9ENTR/7-76       AC J2IK30.1
#=GS A0A090U460_9ENTR/10-78  AC A0A090U460.1
#=GS B2VB73_ERWT9/19-63      AC B2VB73.1
#=GS YKFF_ECOLI/5-74         AC P75677.1
#=GS YKFF_ECOLI/5-74         DR PDB; 2HJJ A; 10-74;
#=GS A0A0A0ZE56_9ENTR/6-77   AC A0A0A0ZE56.1
#=GS A6TIE0_KLEP7/10-80      AC A6TIE0.1
#=GS A0A0G3Q6Q6_KLUIN/7-76   AC A0A0G3Q6Q6.1
A0A0A1BA84_9ENTR/6-77              snesp-------LSLAQARA.......VAAGYQNVFIENLQPAgHFQIAIRNHrdhDRQLIWRNWNYEPDAYDALNSHLQSHGLK-a.
YUBL_YERPE/6-74                    ....a-VLPDDTFTREQAEV.......VAAQYTNVAIEDDQGA.HFRLVVRQ-...NGEMVWRTWNFEPGGTYWLNRYIADYGIRK..
A6TIR7_KLEP7/10-78                 .....KCLADGSFTREQATA.......VAEQFQNVTIEDDQGT.HFRLVVRR-...DGEMIWRGWNFEKGAAYWLNRYIEFYGIRK..
V5CQX1_ENTCL/5-73                  ....t-ELPEGPFTRQQAEA.......VAAQYSNVVIEDDQGT.HFRLVIRH-...ECCMVWRAWNFEPDAGYWLNRYIARYGIRK..
YPJI_ECOLI/15-85                   .sglp----------QWASAdcvagplVSAGITDINIEDDQGI.HVRLIVRDA...EGRMVWRAWNFEPDAGEGFNRYIHRSGIRT..
YUBL_SALTY/10-78                   .....KSLPDGTFTHEQAEA.......VAAQYQNVAIEDDQGT.HLRLVVRK-...DGEMVWRGWNFEPGGEYWLNRCIESHGIRK..
A0A0L0GQB8_9ENTR/7-76              ....t-SLPPGPFTRRQAEA.......VVALYRNIAIEDDQGT.HFRLVIRDS...DNQLIWRAWNFEASAGEWLNRYLVSHGVR-h.
J2IK30_9ENTR/7-76                  ...tp--LPPGSFTREQATA.......VATQYTNLTLEDDHGN.QFRLVIRDS...EGQLIWRAWNFEADAGYWLNRYLLSHGI--pr
A0A090U460_9ENTR/10-78             .....KSLPDGTFTREQAEV.......VAAQYQNVTIEDDQGT.HFRLVVRK-...DGEMVWRVWNFEPGGEYWMNRNIQSYGIRK..
B2VB73_ERWT9/19-63                 ....a-ALGNGTFTREKALN.......VTAAFSNVFIDDDQGS.HFRLVVREP...SGSFI-------------------------..
YKFF_ECOLI/5-74                    ....v-LLPPGPFTRRQAQA.......VTTTYSNITLEDDQGS.HFRLVVRDT...EGRMVWRAWNFEPDAGEGLNRYIRTSGIRT..
#=GR YKFF_ECOLI/5-74         SS    ....X-XXXX----HHHHHH.......HHHH-TTEEEES-SSS.--EEEEE-S...S--EEEEEESSSTTHHHHHHHHHTTTTTTT..
A0A0A0ZE56_9ENTR/6-77              snesp-------LSLAQARA.......VAAGYQNVFIENLQPAgHFQIAIRNHrdhDRQLIWRNWNYEPDAYDALNSHLQSHGLK-a.
A6TIE0_KLEP7/10-80                 .....VSLPDGTFTREQAQV.......VAAQYQNVAIEDDQGT.HFRLVVRHK..dDGSMIWRVWNFEPGGEDIMNRYIRDYGVRK..
A0A0G3Q6Q6_KLUIN/7-76              ...tp--LPPGSFTREQATA.......VATQYTNLTLEDDHGN.QFRLVIRDS...EGQLIWRAWNFEADAGYWLNRYLLSHGI--pr
#=GC SS_cons                       ....X-XXXX----HHHHHH.......HHHH-TTEEEES-SSS.--EEEEE-S...S--EEEEEESSSTTHHHHHHHHHTTTTTTT..
#=GC seq_cons                      ....s..LPsGsFTRcQApA.......VAApYpNVsIEDDQGs.HFRLVlRc....-GphlWRsWNFEPsAt.hLNRYltsaGIR...
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