GenomeNet

Database: Pfam
Entry: DUF905
LinkDB: DUF905
Original site: DUF905 
#=GF ID   DUF905
#=GF AC   PF06006.11
#=GF DE   Bacterial protein of unknown function (DUF905)
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_7072 (release 9.0)
#=GF GA   22.30 22.30;
#=GF TC   28.60 28.40;
#=GF NC   18.70 18.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   19455708
#=GF RT   NMR structure of protein YvyC from Bacillus subtilis reveals
#=GF RT   unexpected structural similarity between two PFAM families.
#=GF RA   Eletsky A, Sukumaran DK, Xiao R, Acton TB, Rost B, Montelione
#=GF RA   GT, Szyperski T;
#=GF RL   Proteins. 2009;76:1037-1041.
#=GF DR   INTERPRO; IPR009253;
#=GF CC   This family consists of several short hypothetical
#=GF CC   Enterobacteria proteins of unknown function. Structural analysis
#=GF CC   of the surface features of the protein YvyC has revealed a
#=GF CC   single cluster of highly conserved residues on the surface.
#=GF CC   Additionally, these residues fall into two groups which lie
#=GF CC   within the two largest of the three cavities identified over the
#=GF CC   surface. The conclusion from this is that these two cavities
#=GF CC   with, Leu 58, Glu 75, Ile 82, and Glu 83 and Pro 86, conserved,
#=GF CC   are likely to be important for the molecular function and
#=GF CC   reflect the cavities found on the surface of the FlaG proteins
#=GF CC   in Pfam:PF03646.
#=GF SQ   22
#=GS A0A0A1BA84_9GAMM/6-77     AC A0A0A1BA84.1
#=GS A0A085H6E3_9ENTR/123-192  AC A0A085H6E3.1
#=GS H5V7Q2_ESCHE/237-306      AC H5V7Q2.1
#=GS A0A163L1L6_9ENTR/10-80    AC A0A163L1L6.1
#=GS YKFF_ECOLI/5-74           AC P75677.1
#=GS YKFF_ECOLI/5-74           DR PDB; 2HJJ A; 10-74;
#=GS A0A0G3Q6Q6_KLUIN/7-76     AC A0A0G3Q6Q6.1
#=GS A0A0D8TUQ0_RAOPL/1-56     AC A0A0D8TUQ0.1
#=GS W1DXZ0_KLEPN/10-80        AC W1DXZ0.1
#=GS A0A181DEM0_9ENTR/5-74     AC A0A181DEM0.1
#=GS YUBL_YERPE/6-74           AC Q7ARC3.1
#=GS V5CQX1_ENTCL/5-73         AC V5CQX1.1
#=GS A6TIR7_KLEP7/10-78        AC A6TIR7.1
#=GS YPJI_ECOLI/15-85          AC P58095.1
#=GS W1DGI1_KLEPN/10-80        AC W1DGI1.1
#=GS YUBL_SALTY/10-78          AC Q93GP6.1
#=GS A0A0L0GQB8_9ENTR/7-76     AC A0A0L0GQB8.1
#=GS W1DZN2_KLEPN/5-74         AC W1DZN2.1
#=GS A0A0J8YEK5_9BACT/6-74     AC A0A0J8YEK5.1
#=GS W1FYD6_ECOLX/17-86        AC W1FYD6.1
#=GS A0A0J8YE47_9BACT/12-65    AC A0A0J8YE47.1
#=GS W1G1Q7_ECOLX/5-73         AC W1G1Q7.1
#=GS A6TIE0_KLEP7/10-80        AC A6TIE0.1
A0A0A1BA84_9GAMM/6-77                ..................snesp-------LSLAQARA.......VAAGYQNVFIENLQPAgHFQIAIRNHrdhDRQLIWRNWNYEPDAYDALNSHLQSHGLK-a.
A0A085H6E3_9ENTR/123-192             ......................g-TLPAGTFTRRQAEA.......TAALYINVGIEDDQHT.HFRLVIRDA...DGQLIWRAWNFEPGAGHDLNTHLQRYGVKK..
H5V7Q2_ESCHE/237-306                 ......................p-LLPPGSFTRQQAEA.......IISRYHNVTIEDDQTT.HFRLVVRDD...DGSMVWRAWNFEPDAGAGLTPYIRRYGIRR..
A0A163L1L6_9ENTR/10-80               .......................VSLPDGTFTREQAQV.......VAAQYQNVAIEDDQGT.HFRLVVRHQ..dDGSMIWRVWNFEPGGEDMMNRYIRDYGVRK..
YKFF_ECOLI/5-74                      ......................v-LLPPGPFTRRQAQA.......VTTTYSNITLEDDQGS.HFRLVVRDT...EGRMVWRAWNFEPDAGEGLNRYIRTSGIRT..
#=GR YKFF_ECOLI/5-74           SS    ......................X-XXXX----HHHHHH.......HHHH-TTEEEES-SSS.--EEEEE-S...S--EEEEEESSSTTHHHHHHHHHTTTTTTT..
A0A0G3Q6Q6_KLUIN/7-76                .....................tp--LPPGSFTREQATA.......VATQYTNLTLEDDHGN.QFRLVIRDS...EGQLIWRAWNFEADAGYWLNRYLLSHGI--pr
A0A0D8TUQ0_RAOPL/1-56                .......................---------------.......VAAQYQNVAIEDDQGT.HFRLVVRHQ..dDGSMIWRVWNFEPGGEDMMNRYIRDYGVRK..
W1DXZ0_KLEPN/10-80                   .......................VSLPDGTFTREQAQV.......VAAQYQNVAIEDDQGT.HFRLVVRHK..dDGSMIWRVWNFEPGGEDIMNRYIRDYGVRK..
A0A181DEM0_9ENTR/5-74                ......................l-LLPPGSFTRQQAEA.......IISRYHNVTIEDDQTT.HFRLVVRDD...DGSMVWRAWNFEPDAGAGLTPYIRRYGIRR..
YUBL_YERPE/6-74                      ......................a-VLPDDTFTREQAEV.......VAAQYTNVAIEDDQGA.HFRLVVRQ-...NGEMVWRTWNFEPGGTYWLNRYIADYGIRK..
V5CQX1_ENTCL/5-73                    ......................t-ELPEGPFTRQQAEA.......VAAQYSNVVIEDDQGT.HFRLVIRH-...ECCMVWRAWNFEPDAGYWLNRYIARYGIRK..
A6TIR7_KLEP7/10-78                   .......................KCLADGSFTREQATA.......VAEQFQNVTIEDDQGT.HFRLVVRR-...DGEMIWRGWNFEKGAAYWLNRYIEFYGIRK..
YPJI_ECOLI/15-85                     ...................sglp----------QWASAdcvagplVSAGITDINIEDDQGI.HVRLIVRDA...EGRMVWRAWNFEPDAGEGFNRYIHRSGIRT..
W1DGI1_KLEPN/10-80                   .......................VSLPDGTFTREQAQV.......VAAQYQNVAIEDDQGT.HFRLVVRHK..dDGSMIWRVWNFEPGGEDIMNRYIRDYGVRK..
YUBL_SALTY/10-78                     .......................KSLPDGTFTHEQAEA.......VAAQYQNVAIEDDQGT.HLRLVVRK-...DGEMVWRGWNFEPGGEYWLNRCIESHGIRK..
A0A0L0GQB8_9ENTR/7-76                ......................t-SLPPGPFTRRQAEA.......VVALYRNIAIEDDQGT.HFRLVIRDS...DNQLIWRAWNFEASAGEWLNRYLVSHGVR-h.
W1DZN2_KLEPN/5-74                    ......................h-LLPQGPFTRQQAEA.......ITCHYHNVCIEDDQGS.HFRLVVRDA...ESRMVWRAWSFEPDAGEGLNRYIRRSGIRT..
A0A0J8YEK5_9BACT/6-74                ......................a-VLPDDTFTREQAEA.......VAAQYANVAIEDDWGS.HFRLVVRK-...DGEMVWRTWNFEPGGTYWLNRYIADYGIRK..
W1FYD6_ECOLX/17-86                   ......................t-SLPPGQFTRRQAEA.......VVTLYHNVTIEDDQGT.HFRLVIRDS...EGTLIWRAWNFEASAGEWLNRYLLSHGIP-k.
A0A0J8YE47_9BACT/12-65               rvlkdsvlvkvssiskyddhqve---------------.......----------------.-----IRDA..hTGQLIWRAWDFEPDFEKELERNLKQ-----f.
W1G1Q7_ECOLX/5-73                    ......................t-ELPDGPFTRQQAEA.......VASQYSNVAIEDDLGT.HFRLVVRH-...ERCMVWRAWNFEPDAGYWLNRYITRYGIRK..
A6TIE0_KLEP7/10-80                   .......................VSLPDGTFTREQAQV.......VAAQYQNVAIEDDQGT.HFRLVVRHK..dDGSMIWRVWNFEPGGEDIMNRYIRDYGVRK..
#=GC SS_cons                         ......................X-XXXX----HHHHHH.......HHHH-TTEEEES-SSS.--EEEEE-S...S--EEEEEESSSTTHHHHHHHHHTTTTTTT..
#=GC seq_cons                        .........................LPsGsFTRpQApA.......VAupYpNVsIEDDQGT.HFRLVVRct...-GpMlWRuWNFEPsusthLNRYIpcaGlR+..
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