GenomeNet

Database: Pfam
Entry: Dendrin
LinkDB: Dendrin
Original site: Dendrin 
#=GF ID   Dendrin
#=GF AC   PF15498.4
#=GF DE   Nephrin and CD2AP-binding protein, Dendrin
#=GF AU   Eberhardt RY, Coggill P, Hetherington K
#=GF SE   Jackhmmer:O94850
#=GF GA   27.00 27.00;
#=GF TC   109.20 35.20;
#=GF NC   21.40 21.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   16464232
#=GF RT   Postsynaptic recruitment of Dendrin depends on both dendritic
#=GF RT   mRNA transport and  synaptic anchoring.
#=GF RA   Kremerskothen J, Kindler S, Finger I, Veltel S, Barnekow A;
#=GF RL   J Neurochem. 2006;96:1659-1666.
#=GF RN   [2]
#=GF RM   17251388
#=GF RT   Expression and subcellular distribution of novel
#=GF RT   glomerulus-associated proteins dendrin, ehd3, sh2d4a, plekhh2,
#=GF RT   and 2310066E14Rik.
#=GF RA   Patrakka J, Xiao Z, Nukui M, Takemoto M, He L, Oddsson A,
#=GF RA   Perisic L, Kaukinen A, Szigyarto CA, Uhlen M, Jalanko H,
#=GF RA   Betsholtz C, Tryggvason K;
#=GF RL   J Am Soc Nephrol. 2007;18:689-697.
#=GF RN   [3]
#=GF RM   18356187
#=GF RT   Dendrin expression in glomerulogenesis and in human minimal
#=GF RT   change nephrotic syndrome.
#=GF RA   Duner F, Patrakka J, Xiao Z, Larsson J, Vlamis-Gardikas A,
#=GF RA   Pettersson E, Tryggvason K, Hultenby K, Wernerson A;
#=GF RL   Nephrol Dial Transplant. 2008;23:2504-2511.
#=GF RN   [4]
#=GF RM   21606645
#=GF RT   Dendrin location in podocytes is associated with disease
#=GF RT   progression in animal and human glomerulopathy.
#=GF RA   Asanuma K, Akiba-Takagi M, Kodama F, Asao R, Nagai Y, Lydia A,
#=GF RA   Fukuda H, Tanaka E, Shibata T, Takahara H, Hidaka T, Asanuma E,
#=GF RA   Kominami E, Ueno T, Tomino Y;
#=GF RL   Am J Nephrol. 2011;33:537-549.
#=GF RN   [5]
#=GF RM   17537921
#=GF RT   Nuclear relocation of the nephrin and CD2AP-binding protein
#=GF RT   dendrin promotes apoptosis of podocytes.
#=GF RA   Asanuma K, Campbell KN, Kim K, Faul C, Mundel P;
#=GF RL   Proc Natl Acad Sci U S A. 2007;104:10134-10139.
#=GF DR   INTERPRO; IPR026500;
#=GF CC   Dendrin is a family of eukaryotic proteins found in the
#=GF CC   podocytes of the kidneys. Dendrin, originally identified in
#=GF CC   telencephalic dendrites, is a constituent of the slit diaphragm,
#=GF CC   SD, complex of podocytes, where it directly binds to nephrin and
#=GF CC   CD2AP. Kidney podocytes and their slit diaphragms (SDs) form the
#=GF CC   final barrier to urinary protein loss. SD proteins also
#=GF CC   participate in intracellular signalling pathways. Dendrin
#=GF CC   appears to prevent programmed cell death (apoptosis) through its
#=GF CC   binding to nephrin. The SD protein nephrin serves as a component
#=GF CC   of a signalling complex that directly links podocyte junctional
#=GF CC   integrity to actin cytoskeletal dynamics. Thus, dendrin is
#=GF CC   identified as an SD family with proapoptotic signalling
#=GF CC   properties that accumulates in the podocyte nucleus in response
#=GF CC   to glomerular injury.
#=GF SQ   42
#=GS G3I6J1_CRIGR/353-463      AC G3I6J1.1
#=GS V8PD67_OPHHA/290-561      AC V8PD67.1
#=GS A0A0D9R1L7_CHLSB/55-710   AC A0A0D9R1L7.1
#=GS A0A0G2JU85_RAT/1-653      AC A0A0G2JU85.1
#=GS A0A091DMT6_FUKDA/55-141   AC A0A091DMT6.1
#=GS A6QPL7_BOVIN/1-622        AC A6QPL7.1
#=GS L5KD64_PTEAL/55-704       AC L5KD64.1
#=GS M3VU31_FELCA/55-705       AC M3VU31.1
#=GS L8Y728_TUPCH/55-157       AC L8Y728.1
#=GS G3VKE5_SARHA/55-716       AC G3VKE5.1
#=GS F1SJ13_PIG/55-705         AC F1SJ13.1
#=GS V8PD67_OPHHA/27-226       AC V8PD67.1
#=GS F6SLS9_MACMU/1-656        AC F6SLS9.1
#=GS G1KYY8_ANOCA/1-73         AC G1KYY8.1
#=GS G1S849_NOMLE/280-615      AC G1S849.1
#=GS L8Y728_TUPCH/531-589      AC L8Y728.1
#=GS S9YFK7_9CETA/320-443      AC S9YFK7.1
#=GS F7BXX9_HORSE/1-630        AC F7BXX9.1
#=GS F7IG77_CALJA/55-710       AC F7IG77.1
#=GS E2RTH4_CANLF/55-702       AC E2RTH4.2
#=GS DEND_MOUSE/55-708         AC Q80TS7.3
#=GS G3U5X4_LOXAF/1-626        AC G3U5X4.1
#=GS G1LKB8_AILME/51-689       AC G1LKB8.1
#=GS H0Y156_OTOGA/55-712       AC H0Y156.1
#=GS DEND_HUMAN/55-709         AC O94850.3
#=GS DEND_RAT/55-707           AC P50617.3
#=GS G3R6N2_GORGO/55-710       AC G3R6N2.1
#=GS H2NH62_PONAB/55-710       AC H2NH62.2
#=GS L8Y728_TUPCH/153-533      AC L8Y728.1
#=GS A0A096N5Z4_PAPAN/123-778  AC A0A096N5Z4.1
#=GS M3YTF1_MUSPF/55-701       AC M3YTF1.1
#=GS I3N3B4_ICTTR/55-709       AC I3N3B4.1
#=GS G1SV31_RABIT/42-693       AC G1SV31.2
#=GS G5AU33_HETGA/125-647      AC G5AU33.1
#=GS S9YFK7_9CETA/439-511      AC S9YFK7.1
#=GS A0A091DMT6_FUKDA/138-222  AC A0A091DMT6.1
#=GS H2Q5U5_PANTR/55-708       AC H2Q5U5.1
#=GS H0UZS0_CAVPO/1-650        AC H0UZS0.1
#=GS G1S849_NOMLE/55-284       AC G1S849.1
#=GS G3I6J1_CRIGR/1-358        AC G3I6J1.1
#=GS G1KYY8_ANOCA/164-409      AC G1KYY8.1
#=GS G5AU33_HETGA/56-126       AC G5AU33.1
G3I6J1_CRIGR/353-463                 ........................................................................................................vvht----------------------------------------------------------------------------------..------......-----------------------------------...---------.---------------------------------.---------------------.--------------------...-------------------------------------------------.----------------------------.----------------------------------------.---------------....--------.--------.--------------....------------....------------......---.-----------------------------------------------.--------------------------------..----.....----------.---------------------....----------------------.----.----.-----.......-----QPGPYAGALREAVSRIRRHTAPDSDSDEA.EELSVHSGSSDGSDTDAPGASWRNEMTLPAVGNT..RPREGGKTAKPSDSIREVLDVISQTEEEGLFGEDIRKTPQGKRE...........................
V8PD67_OPHHA/290-561                 ................................................................................................krsqvmplpchp----------------------------------------------------------------------------------..------......-----------------------------------...---------.---------------------------------.---------------------.--------------------...-------------------------------------------------.----------------------------.----------------------------------------.---------------....------SQhTLPAGWGFsHAAGWCRSKRDGSRakekRCQDFFPRWKEPspsrKLAGSQPALSKS......MPRrHGGLFVIDATCVVIQAHYIPSPRMEQVCYLAQGEAGTIKSPTSPGSP.GPTSMEERAARILGLPLRELGATEAGQGIMTPkiPGPE.....NGAIPGDSSG.REKVKRVPSAPDSPRK----L....SGPPTPNHSQVGPAKQEPTYLAgKGSA.ASPC.PRRHGlpqrkdePGMSAQSQSYICDLKEAMSRIRRHTAPDSDTDEE.LE--------------------------------..--------------------------------------------kenngpr....................
A0A0D9R1L7_CHLSB/55-710              ............................................................................................................MDFQASHWARGFQNRTCGPRPGSPQPPPRRPWASRVLQEATNWRAGPLAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNAPRAAQPAGLPATLRLERLAPVGRAPRP...SAQPQSDPG.SAWAGPWGGRRPGPPSYEAHLLLRGSAGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPGHSQVPTSSAPPPT...PARTEGGRTKKRLDPRIYRDVLGAWGLRQGQGLLGGSPGCGAARTRPEP.GKGVVEKSLGLAAADLNSGSDSHPQAKA.TGSAGTETTPAGSATAAPSAPRPAPRSRHHLKGSREGKEG.KEQIWFPKCWIPSPK....KQPPRHSQ.TLPRPWAP.GGTGWRESLGLGEG....AGPDTLEGWKAT....RRAHTLPRSSQG......PSR.GEGVFVIDATCVVIRSQYVPTPRTQQVQLLPSGVTRVVGESASQSKP.GKEESEGATVFPSPCQKRLSNSRLLHQPGGGR..GGEA.....EGGRPGDSSL.EERTSRILGLPAPEVNLRDAP....TQPGSPEHQALGPGASGAQGRA.EGSE.VAVV.QRRAG.......RGWARTPGPYAGALREAVSRIRRHTAPDSDTDEA.EELSVHSGSSDGSDTEAPGASWRNERTLPGVGNS..SPEEDGKTAELSDSVGEILDVISQTEEVLFGVRDIRGTQQGNRK...........................
A0A0G2JU85_RAT/1-653                 ............................................................................................................MDIQASYWARGPQNRTCRLRPGSPEPPPRRPWASRVLQEATNWRAGPPAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPLGQ......PRPELRNALRAAQPTGFPVFSRPERFGQVGRAPRP...SALPQGDPG.VAWAGPWGGRRPGPPSYEAHLLLRGAAGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPELSRAPTSSAPVPA...TTRTEGGRTKKRLDPRIYRDVLGAWGLRQGRGLLGGAPGCAAARARPES.CKGAVEKSSGLAAAGLNSGGDGHSQAKT.TG-PVTEVALSGST--ISSPPRPVPRSRQHLRGSRKGKEG.SEEMWLPTCWLSSPK....KPPVRHSQ.TLPRPWAP.GGTGWKESLGQREG....TEHETLEVWKVT....RRAHTLPRSSRG......PAG.REGIFVIDATCVVIKSQYVPTPRTQQRQLAPSGESCIVSDSLRQPKPcLEEEGKGAAANPSVCQKRLLSSRVLNPPSEGR..EFEA.....EGRQQGDSSL.EERSSSGLGFPVGEVNPRDAP....THPGSPEHSTLGPAAPGCAGSV.KGPE.AAGV.PRRAG.......GGWARTPGPYAGALREAVSRIRRHTAPDSDSDEA.EDLSAHSGSSDGSDTDAPGASWRNERTLPAVGNT..RPREGGKTAELGDSIGEILDVISQTEEGL-VREDTRKTPQGKRE...........................
A0A091DMT6_FUKDA/55-141              ............................................................................................................MEFQASPWARGSQSRMCRPRPGSPEPPPRRPWASRVLQEATNWRAGLPAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPH--......-----------------------------------...---------.---------------------------------.---------------------.--------------------...-------------------------------------------------.----------------------------.----------------------------------------.---------------....--------.--------.--------------....------------....------------......---.-----------------------------------------------.--------------------------------..----.....----------.---------------------....----------------------.----.----.-----.......----------------------------------.----------------------------------..--------------------------------------------s..........................
A6QPL7_BOVIN/1-622                   ............................................................................................................MDFQASHWLRGPQSRTCGPRPGSPEPPPRRPWASRVLQEATNWRAGPPAEARAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNALRVAHSAGLPAPSRPERLGSVGRPPRP...SAQPQSNPG.AAWAGPWGGRRPGPPSYEAHLLLRGAAGMAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPEPSQARSSSTCAPT...--RTEGGCAKKRLDPRIYRDVLGAWGLRQGRGLLGGSPGCGTDRPRLES.GKGPAEKSLRLAAAGLKSGSDGHPQAKA.AGSPGTV--PAGSATATPSPPRPTPRSRPHPRGSGEGREG.RDQTWLPKRWVPSIK....KQPPRHSQ.TLPRPWAP.GGTGWIESLGHRGE....AGPETLEGWKAT....RRPHTLPRSSRG......PAR.GEGVFVIDATCVVIRSQYVPTPRTQHVQLLPAGVPRLVGNAPSQPKP.NKEEGEGAAVLPSPCRKLPLSSRPSLQPSEGR..GLEA.....ERGKPADSSL.EERASRILGLPVGEVNLQDPP....TQPGSPEHSALGPAASRGARGA.EGSEkVASG.TRRAG.......RGWARAPGPYAGALREAVSRIRRHTAPDSDSDEA.AELSVHSSSSDASDTEASGASWRKERTGPP----..---EGGKTAELSGNAREI--------------------------es.........................
L5KD64_PTEAL/55-704                  ............................................................................................................MDFQASHWARGPQSRTCGPRLGSPEPLPRRPWASRVLQEATNWRAGPPAEARAREQEKRKAASQEREAKETERKRRKAGGAR..RSPLGR......PCPEVRNAPRVAQHTGLPAPSRPERLGLVWRPPRP...SAQLQSDPE.AAWAGPWGGRRPGPPSYEAHLLLRGAAGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPEPSQAPASSAPAPT...PARTEGGCTKKRLDPRIYRDVLGAWGLRQGRGLLGGSPGCGTARPRLEP.RKRATEKSLGLADAGQNNSSGGYPQAKA.AGSPGTATAPAGSAAATPSPPRPAPRSRPHVKGSWEGKEG.REQSWLPKCWISSLK....KQPPRLSQ.TLPRPWAP.GGTGWRDSLGHREG....AKTETLADWKAT....RRAHTLPRSSRG......PVR.GEGVFVIDATRVVIRSQYVPTPRTQHVQFLPAGVPRPEGDALGQPKP.NKKEGKGAAVFPPPCQKLQLSSRLSHQQGGGR..GFEA.....EGGKPADSSL.EERASRILGLPMGEVNLQKVP....SQPVSSEHSALSPVASGGAGSA.KGLReVVAV.PRPTN.......RSWTRIPGPYAGALREAVSRIRRHTAPDSDSDEA.AELSVHSGSSDGSDTEASGASWRNERIRPQ----..---EGRKTAELSDSIREIIDVISRTEEALFGARDTKGTPQGNRE...........................
M3VU31_FELCA/55-705                  ............................................................................................................MDFQASHWARGPQSRTCGPRSGSPEPPPRRPWASRVLQEATNWRAGPPAEARAREQEKRKAASQEREAKETERKRRKAGGAR..RSPLGR......PRPEPRNAPRVAQPVGPSAPSRPERLGLAGRPPRP...SAQPQSDPG.AAWAGPWGGRRSGPPSYEAHLLLRGAAGTALRR.RWDRPPPYVAPPSYEGPHRTL.GSKRGPEPSQAPASAACAPT...PARTEGGFTKKRLDPRIYRDVLGAWGLRQGRGLLGGSPGCGTARPRLES.GKGAVEKSLGLASAGPNSGSDSHPQAKA.VGSPSSETAPAGLAAATPSPPRPAPRSRPHLKGPGEGKES.REQSWLPKGWIPSLK....RQPPRHSQ.TLPRPWAP.GGTGWRESLGHREG....AGPETLEGWKGA....RRAHTLPRSSRG......PAR.GEGVFVIDATCVVIRSQYVPTPRTQHVQLLPNGVPRVGGDAPNQPKP.NKEEVEGVAAFPSPCQKLLLSSRLSHQLGGGR..GFEA.....EGGKPPDSSL.EERASRILGLPVGEVNLQDAP....AQPGSPERSVLGPPASGGAGSA.EGSEeVAAVpPRRAG.......RGWARTPGPYAGALREAVSRIRRHTAPDSDSDEA.AELSVHSGSSDGSDTEASGASWRNERPRPG----..---EGGKTAELSDSIREILDVINRTEEAFFGERDTKGMPQGNRE...........................
L8Y728_TUPCH/55-157                  ............................................................................................................MDFQASHWARGLQSRTCGPRPGAPEPPPRRPWASRVLQEATNWRAGPPAELRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNAPRAAQC---------------------...---------.---------------------------------.---------------------.--------------------...-------------------------------------------------.----------------------------.----------------------------------------.---------------....--------.--------.--------------....------------....------------......---.-----------------------------------------------.--------------------------------..----.....----------.---------------------....----------------------.----.----.-----.......----------------------------------.----------------------------------..--------------------------------------------a..........................
G3VKE5_SARHA/55-716                  ............................................................................................................MDPTGGPWVQEPSSHRYGLDKKPPERLLRRAWVPRVLQEATNWGTGHPPEIRPREQEKRKAASQEREAKETERKRRKGGGVRkpRSPLGRarggggSRQEPGNVPKTAQPKVRQFPWLPGHLGPAGRPPRP...AAQSLRVPGtAARAGLRVGRPSGPPSYEAHLLLRGAAGPIPRK.RWDRPPPYVAPPSYDGPHRTL.GAKRPPQLPGLPAPLAPAPTlegKEREE--RPKKRLDPRIYRDVLGAWGIRQGRGALGGFPACGGLG----L.GGKTSDKVSGVFLGGLNSNCSES-----.CSQPGAN-QIARAATLTSGTSQTTARTQVPLRDVSEGERA.GEQSWSRETGGPSPG....DQVAQHSQ.TLPRPWAP.GSPREKESPGEGDGy..qRSPKLPTDWKET....HRAHTVPRSPHS......SAG.ENGVFVIDATCVVIRAQFVPTPQIQHVQLLSSPGPRNGGNSLAFQKP.GKEEGEEEQAFTSPCQKLLQNSRLFDQLSKGF..-SDAwgegvEAGIPEDPSL.KERASRILGLPIRELDLGVSPnkcnSDPGGPNE-----TAARCADVA.RDSEpAPRV.LRPAG.......PGRARDPGPYAGALREAVSRIRRHTAPDSDSDEA.PECGARSCSSEGSDTEASGTSRQPEQSLPGTSGD..QGEAGRRAGELRDCIREILDVICQTEEALFRAEGSAQGKQGGG-h..........................
F1SJ13_PIG/55-705                    ............................................................................................................MDFQASHWARWPQSRTCGPRPGSPEPPPRRPWASRVLQEATNWRAGPPAEARAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNAPRVAQLAGLPASSRPERLGSVGRPSRPfapSAQPQSNPG.AAWAGPWGGRRPGPPSYEAHLLLRGAAGMAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGAEPSQAPASSAPAP-...-ARTEGVCTKKRLDPRIYRDVLGAWGLRQGRGLLGGSPGCGTGRPRLES.GKGAAEKSLRPAAAGLKSGSDRHPQAKA.AGSPGAETLPAGSATVTPSPPRPAPRSRPHPTGSGEGREG.REQSWLPKCWIPSVK....KQLPRHSQ.TLPRPWAP.GGTGWRESLGHREE....AGPETLEGWKAT....RRPHTLPRSSRG......RAR.GEGVFVIDATCVVIRSQYVPTPRTQHVQLLPAGVPRAVEDAPSPPKS.NKEEGEGATVFPSPSQKLPLSSRPSHQPGGGR..GLEA.....EGGKPADSSL.EERASRILGLPVGEVNLQDPP....TQPGSPEHSALGPAPSGGAGGA.ERSEeVAAV.PQRAG.......RGWARTPGPYAGALREAVSRIRRHTAPDSDSDEA.AELSVHSGSSDGSDTEASGASWRSERTGPR----..---EGGKTAELSDNVRGILDVISRTEEVLFGAGDNKGTPQGNRE...........................
V8PD67_OPHHA/27-226                  lekrlmsdfspcrhcpsfhvlqdstnwhdaqfpagwgplkqeghwfsrkgwgkrttsspkaprhhspsydgynpvcqrdmnwganhttkgdpkapapggslvscrwnq----------------------------------------------------------------------------------..------......-----------------------------------...--------G.ASAKKRRELPARAPPSYEAHMLLRLRAQQGPRKeNWSHPPPYLAPPSYEASHHRVqPQQRAGKSD-----------...-------------------------------------------------.----------------------------.----------------------------------------.---------------....--------.--------.--------------....------------....------------......---.-----------------------------------------------.--------------------------------..----.....----------.---------------------....----------------------.----.----.-----.......----------------------------------.----------------------------------..--------------------------------------------svgkliqngaakkyrereagcesepl.
F6SLS9_MACMU/1-656                   ............................................................................................................MDFQASHWARGFQNRTCGPRPGSPQPPPRRPWASRVLQEATNWRAGPLAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNAPRAAQPAGLPATLRPERLALVGRAPRP...SAQPQSDPG.SAWAGPWGGRRPGPPSYEAHLMLRGSAGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPGHSQVPTSSAPPPT...PARTEGGRTKKRLDPRIYRDVLGAWGLRQGQGLLGGSPGCGAARARPEP.GKGVVEKSLGLAAADLNSGSDSHPQAKA.TGSAGTETTPAGSATAAPSAPRPAPRSRHHLKGSREGKEG.KEQIWFPKCWIPSPK....KQPPRHSQ.TLPRPWAP.GGTGWRESLGLAEG....AGPETLEGWKAT....RRAHTLPRSSQG......PSR.GEGVFVIDATCVVIRSQYVPTPRTQQVQLLPSGVTRVVGESASQSKP.GKEESEGATVFPSPCRKRLSNSRLLHQPGGGR..GGEA.....EGGRSGHSSL.EERTSRILGLPAPEVNLRDAP....TQPGSPEHQALGPGASGAQGRA.EGSE.VAVV.QRRAG.......RGWARTPGPYAGALREAVSRIRRHTAPDSDTDEA.EELSVHSGSSDGSDTEAPGASWRNERTLPGVGNS..SPEEDGKTAELSDSVGEILDVISQTEEVLFGVRDIRGTQQGNRK...........................
G1KYY8_ANOCA/1-73                    ............................................................................................................----------------------------------------------------------------------------------..------......-----------------------------------...---------.-------------PPSYEAHMLLRLRAGQGPRKeNWPHPPPYVAPPSYEAPHCTV.RPQS----------------...-------------------------------------------------.----------------------------.----------------------------------------.---------------....--------.--------.--------------....------------....------------......---.-----------------------------------------------.--------------------------------..----.....----------.---------------------....----------------------.----.----.-----.......----------------------------------.----------------------------------..--------------------------------------------kllpcqhphkgaltgkqiqtvgpkkyg
G1S849_NOMLE/280-615                 ..........................................................................................................dk----------------------------------------------------------------------------------..------......-----------------------------------...---------.---------------------------------.---------------------.--------------------...-------------------------------------------------.----------------------------.---------------------------------------E.GNRIWFPKCWIPPLK....SNRPAISQ.TLPRPWAP.GGTGWRESLGLGEG....AGPETLEGWKAT....RRAHTLPRSSQG......PSR.GEGVFVIDATCVVIRSQYVPTPRTQQVQLLPSGVTRVVGDSPSQSKP.GKEEGEGATVFPSPCQKRLSSSRLLHQPGGGR..GGEA.....EGGRPEDSSL.EERTSRILGLPAPEVNLRDAP....TQPGSPEHQALGPAASGTQGTA.EGSG.VAVV.QRRAG.......RVWARTPAPYAGALREAVSRIRRHTAPDSDTDEA.EELSVHSGSSDGSDTEAPGASWRNERTLPGVGNS..SPEEDGKTAELSDSVGEILDVMSQTEEVLFGVRDIRGTQQGNRK...........................
L8Y728_TUPCH/531-589                 ..........................................................................................................ag----------------------------------------------------------------------------------..------......-----------------------------------...---------.---------------------------------.---------------------.--------------------...-------------------------------------------------.----------------------------.----------------------------------------.---------------....--------.--------.--------------....------------....------------......---.-----------------------------------------------.--------------------------------..----.....----------.---------------------....----------------------.----.----.-----.......-----------------------------DSDEA.EEPSVHSGSSDGSDAEAPGASWRNERTLPGDGNP..RPGEGGKAAELRQ-------------------------------ypgds......................
S9YFK7_9CETA/320-443                 .......................................................................................................qalvl----------------------------------------------------------------------------------..------......-----------------------------------...---------.---------------------------------.---------------------.--------------------...-------------------------------------------------.----------------------------.----------------------------------------.---------------....--------.--------.--------------....------------....------------......---.-TGVFVIDATCVVIRSQYVPTPRTQHVQLLPAGVPRVVGDTPSQPKP.NKEEGEEAAVFPSPCQKLLLSSSLSHQPGGGR..RFEA.....EGGKPADSSL.EERASRILGLPVGEVNLQDAP....TLPAA-----------------.----.----.-----.......----------------------------------.----------------------------------..--------------------------------------------e..........................
F7BXX9_HORSE/1-630                   ............................................................................................................-------------------RPGSPEPPPRRPWASRVLQEATNWRAGPPAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRLEPRNAPRVAQLAGLPAPSRPERLGLVGRPPRP...FAQLQSDPG.AAWARPWGGRRPGPPSYEAHLLLRGAAGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GAKRGPEPSRAPASSAPAPT...PARTEGGCTKKKLDPRIYRDVLGAWGLRQGRGLLGGSPGCRTARPKLES.GKGAAEKSLGLAAAGLNSGSDGHPQAKA.AGSPGTETAPAGSATTTPSPPRPAPRSRAHLNGSGEGKEG.REHSWLRKCWIPSLK....KQLPRHSQ.TLPRPWAP.GGTGWRESLGHREG....AGPETLEGRRAT....RRAHTLPRSSRG......PTP.GEGVFVIDATCVVIRSQYVPTPRTQHVQLLSSGVPRVMGDAPSQAKP.KKEEGEGAALFPSSCQKLLTSSRLSHQPGEGR..EFEA.....EGGKPADSSL.EERASRILGLPVGEVNLQDAR....TQPGNPEHSALGPAASGGAGSA.EASEeAAVV.PRRAG.......RGWARTPGPYAGALREAVSRIRRHTAPDSDSDEA.AELSVHSGSSDGSDTEASGAPWRNERPRPR----..---EGGK-TELSDSMGELLDVTSQTREALFRARDTKGTPHGNRE...........................
F7IG77_CALJA/55-710                  ............................................................................................................MDFQASHWARGFQNRTCGPRPGSPQPPPRRPWASRVLQEATNWRAGPLAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPQGR......PRPEPRNAPRATQPAGLPAPSRPELLAQVGRAPRP...FAQPQSDPG.SAWAGPWGGRRPGPPSYEAHLLLRGSASTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPGHSQAPASSAPAPT...PSRTEGGRMKKRLDPRIYRDVLGAWGLRHGQGLLGGSPGCGAARARPES.GKGFVEKSLGLAAADLNSGRDSHPQVKA.TGSPGTETAPAGSATAAPSAPRPAPRSRHHIKGSREGKKG.REQIWFPKCWIPSPK....KQPPRHSQ.TLPRPWAP.GGTGWRESLGLGEG....AGPETLECWKAT....RRAHTLPRSSQG......PSR.GEGVFVIDATCVVIRSQYVPTPRTQQVQLLPSGVPRVVGDVPSQSKP.GKEDSERATIFPSPCQKLPSSSHLLHQPSEGG..GGEA.....EGGRPGDSSL.EERTFSILGLPAPEVNLRDAP....TQPGSPEHQALGPAASGARSRA.EGSE.VAVV.QRRSG.......RGWARTPGPYAGALREAVSRIRRHTAPDSDTDEA.EELSVHSGSSDGSDTETLGASLRNERTLPGVGNS..PPEEGGKTAELSDRVGEIVDVVSETEEVLFGVRDIKGTQQGNRK...........................
E2RTH4_CANLF/55-702                  ............................................................................................................MDFQASHWARGPQSRTCGPRPGSPEPPPRRPWASRVLQEATNWRAGPPAEARAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRSGPRVAQPVGPPAPSRPERLGPAGRPPRP...SAQPQSDPG.AAWAGPWGGRRPGPPSYEAHLLLRGAAGTALRR.RWDRPPPYVAPPSYEGPHRTL.GSKRGPEPPQAPAPAASAPT...PARTEGGCAKKRLDPRIYRDVLGAWGLRQGRGLLGGSPGCGTAAPRPEA.GKGAAERSLGPAAAGLSAGSDGRPQARA.AGSPSAQTAPAGSAPAARSPPRPAPRARPRLKGSEEGKEN.REQSWLPKCWVPSRK....RQPPRQSQ.TLPRPWAP.GGTGWSESPGLRAG....AGPS--EGGKGT....RRAHTLPRSARG......PAR.GEGVFVIDATCVVIRSQYVPTPRTQHVQLLPAGVPRAAGDAPSPPGP.SQEEGEGAAALPSPCQKLLPSSRPSHQLGGGR..GFEA.....EGGKPADSSL.EERASRILGLPVGEVNLRDAP....AQPGSPERSALGPAASGGAAPA.EGPEgVAAA.PRRAG.......RGWARTPGPYAGALREAVSRIRRHTAPDSDSDEA.AELSVQSGSSDGSDTEASGASWRKEPPRPG----..---DGGKTAELSDSVRDILEVISRPEESLFGTRDSKGVPQGNRE...........................
DEND_MOUSE/55-708                    ............................................................................................................MDIQASYWARGPQSRTCRLRPGSPEPPPRRPWASRVLQEATNWRAGPPAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPLGQ......PRPEPRNALRAAQPTGFPVFSRPERFGQVGRAPRP...SVLPQGDPG.VAWAGPWGGRRPGPPSYEAHLLLRGSAGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPELSRAPTSSAPVPA...TTRTEGGRTKKRLDPRIYRDVLGAWGLRQGRGLLGGAPGCTAARARPES.CKGAIEKSSGLVAAGLNSAGDSHSQGKT.TGGPGTDAALSRSA--ISSPPRPVPRSRQHLRGSRKGKEG.SEQIWLPTCWLASPK....KPPVRHSQ.TLPRPWAP.GGTGWKESLGQREG....AEHETLEVWKVT....RRAHTLPRISRG......PAG.REGIFVIDATCVVIKSQYVPTPRTQQGQLVPSGESCSVSDSLSQPKPcHEEEGEGAAANPSVCQKRLLSSRVLNQPSEGR..ECEA.....EVGQQGDSSL.EERSSSGLGFPVGEVNPRDAP....TQPGSQEHPTLGPAAPVCAGSL.KGSE.AAGV.PRRAG.......GGWARTPGPYAGALREAVSRIRRHTAPDSDSDEA.EDLSVHSGSSDGSDTDAPGASWRNERTLPALGNT..RPREGGKTAGLSDSIREIVDVISQTEEG-FIREDTRKTPQGNRE...........................
G3U5X4_LOXAF/1-626                   ............................................................................................................MDSQTSHWARWTQSRTCGPRPGSPEPPPRRLWASRVLQEATNWRGGHPAEARAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNAPRVAHPAVLPASSRPERFVPLGRAPRP...SAQPQSILG.AAWPGPWGGRRPGPPSYEAHLLLRGAAGTAPRR.RWDRPPPYVPPPSYDGPHRTL.GTKRGPELTQAPASPDPAPI...PARTETGRAKKRLDPRIYRDVLGAWGLRQGRGLLGGSPGCGVARARSEF.GKGAAERSLGLAVAGLSNGSDSHSAAKA.PGSPGAKTVPTGPATATPSPPRPAPRSRPHLKGSREGKEN.VEQSWLLKRWISSPK....KQPPRHSQ.TLPRPWAP.GGTGWKEYLGHREE....AETETLKGWKVT....RRAHTLPRSSRR......PTC.GEGVFVIDATCVVIRSQYVPTPQTQHMRLLPSGVPRVGGDAPSRLQC.GKEEGEGPAAFPSPCQKLLSSSGLSHQPSAGR..GSEA.....EGGEPEDSSL.QERASRILGLPVSEVNLRDVP....RQPGSPEHPALGPAASGSVGSA.EGSKeVTAV.PRRVG.......RSWARTPGPYAGALREAVSRIRRHTAPDSDSDEA.AELSVHSGSSDGSDTEASGTFWRSEQTQPGVGGPtaEPREGGKRVEL---------------------------------...........................
G1LKB8_AILME/51-689                  ............................................................................................................MDFQASHWARGPQSRTCGPRPGSPEPPPRRPWASRVLQEATNWR---PAEARAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNAPRVAQPVGPPAPSRPERLGPAGPPPRP...A--PQSDPG.AAWAGPWGGRRPGPPSYEAHLLLRGAAGTALRR.RWDRPPPYVAPPSYEGPHRTL.GSKRGPEPSQAPASAASAPT...PARTEGGYAKKRLDPRIYRDVLGAWGLRQGRGLLGGSPGCGT---RLES.SKGAAEKSLGLATAGLNSGSDGHAQAKA.AGSPSTETAPAGLATATPSPPRPAPRSRPHLKGSGEGKES.KEQTWLPKCWLPSLK....KQPPRQSQ.TLPRPWAP.GGTGWRESLGHREG....AGPETLEGWKGT....RRAHTLPRISRG......PAR.GEGVFVIDATCVVIRSQYVPTPRTQHVQLLPDGVPRVVGDAPTQPKP.NKEEGEGAAAFPSPCQKLLLSSPLSHQLGGGR..GFEA.....EGGEPADSSL.EERASRILGLPVGEVNLQDA-....-QPGSPERSALGPAASGSTLRA.EGSEeVAGA.PRR-G.......RGWARTPGPYAGALREAVSRIRRHTAPDSDSDEA.AELSVHSGSSDGSDTEASGASWRNERPRPG----..---EGGKTAELSDSIREILDVISRTEEALFGTRDAKGIPQGNRE...........................
H0Y156_OTOGA/55-712                  ............................................................................................................MDFQANHWARGSQSRTCGPRPGSPEVPPRRPWASRVLQEATNWRAGSLAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRLEPRNAPRAAQPARLLALSPPERLGPVGRAPRS...PAQPHRDPG.SAWAGPWGGRRPGPPSYEAHLLLRGSTGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPALSQAPTLSAPAPT...PARTEGGRTKKRLDPRIYRDVLGAWGLRQGQGLLGGSPGCGAAIARPEF.GKGAAEKSVGLAAAGLNSGSYSHSQAKA.TGRPSTKTAPSGSATATPSPPRPTPRARQHLKGSREGKEG.REPIWFPKCWIPSPKgslkRQPARHSQ.TLPRPWAP.GGTGWKESLGYREG....VGPEALEGWKTT....RRAHTLPRSSRR......PAP.GEGVFVIDATCVVIRSQYVPTPQTQQVQLLPSGVPRVVGDAPSQPKA.GKEEGEGATVSPPPCQKLLLSSRLLHQPGQGL..GCEA.....EGGKLGDTLL.EERASRILGLPVGEVNLRDAP....TQPGTPEHQALGPAALGGIGRT.EGSE.VVAV.QWRAG.......RGWARNPGPYAGALREAVSRIRRHTAPDSDTDEA.EELSVHSSSYEGSDTEAPGASWRNERTLPGVGNS..--QEGGKTAELSDSIQEILDVISQTEEALFRARDTKGTPQENRE...........................
DEND_HUMAN/55-709                    ............................................................................................................MDFQASHWARGFQNRTCGPRPGSPQPPPRRPWASRVLQEATNWRAGPLAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNAPRVAQLAGLPAPLRPERLAPVGRAPRP...SAQPQSDPG.SAWAGPWGGRRPGPPSYEAHLLLRGSAGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPGNSQVPTSSAPAAT...PARTDGGRTKKRLDPRIYRDVLGAWGLRQGQGLLGGSPGCGAARARPEP.GKGVVEKSLGLAAADLNSGSDSHPQAKA.TGSAGTEIAPAGSATAAPCAPHPAPRSRHHLKGSREGKEG.-EQIWFPKCWIPSPK....KQPPRHSQ.TLPRPWAP.GGTGWRESLGLGEG....AGPETLEGWKAT....RRAHTLPRSSQG......LSR.GEGVFVIDATCVVIRSQYVPTPRTQQVQLLPSGVTRVVGDSPSQSKP.GKEEGEGATVFPSPCQKRLSSSRLLHQPGGGR..GGEA.....EGGRPGDSTL.EERTFRILGLPAPEVNLRDAP....TQPGSPEHQALGPAASGAQGRA.EGSE.VAVV.QRRAG.......RGWARTPGPYAGALREAVSRIRRHTAPDSDTDEA.EELSVHSGSSDGSDTEAPGASWRNERTLPEVGNS..SPEEDGKTAELSDSVGEILDVISQTEEVLFGVRDIRGTQQGNRK...........................
DEND_RAT/55-707                      ............................................................................................................MDIQASYWARGPQNRTCRLRPGSPEPPPRRPWASRVLQEATNWRAGPPAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPLGQ......PRPELRNALRAAQPTGFPVFSRPERFGQVGRAPRP...SALPQGDPG.VAWAGPWGGRRPGPPSYEAHLLLRGAAGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPELSRAPTSSAPVPA...TTRTEGGRTKKRLDPRIYRDVLGAWGLRQGRGLLGGAPGCAAARARPES.CKGAVEKSSGLAAAGLNSGGDGHSQAKT.TG-PVTEVALSGST--ISSPPRPVPRSRQHLRGSRKGKEG.SEEMWLPTCWLSSPK....KPPVRHSQ.TLPRPWAP.GGTGWKESLGQREG....TEHETLEVWKVT....RRAHTLPRSSRG......PAG.REGIFVIDATCVVIKSQYVPTPRTQQRQLAPSGESCIVSDSLRQPKPcLEEEGKGAAANPSVCQKRLLSSRVLNPPSEGR..EFEA.....EGRQQGDSSL.EERSSSGLGFPVGEVNPRDAP....THPGSPEHSTLGPAAPGCAGSV.KGPE.AAGV.PRRAG.......GGWARTPGPYAGALREAVSRIRRHTAPDSDSDEA.EDLSAHSGSSDGSDTDAPGASWRNERTLPAVGNT..RPREGGKTAELGDSIGEILDVISQTEEGL-VREDTRKTPQGKRE...........................
G3R6N2_GORGO/55-710                  ............................................................................................................MDFQASHWARGFQNRTCGPRPGSPQPPPRRPWASRVLQEATNWRAGPLAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNAPRAAQLAGIPAPLRPERLAPVGRAPRP...SAQPQSDPG.SAWAGPWGGRRPGPPSYEAHLLLRGSAGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPGNSQVPTSSAPAAT...PARTEGGRTKKRLDPRIYRDVLGAWGLRQGQGLLGGSPGCGAARARPEP.GKGVVEKSLGLAAADLNSGSDSHPQAKA.TGSAGTEIAPAGSATAAPCAPRPAPRSRHHLKGSREGKEG.REQIWFPKCWIPSPK....KQPPRHSQ.TLPRPWAP.GGTGWRESLGLGEG....AGPETLEGWKGT....RRAHTLPRSSQG......LSR.GEGVFVIDATCVVIRSQYVPTPRTQQVQLLPSGVTRVVGDSPSQSKP.GKEEGEGVTVFPSPCQKRLSSSRLLHQPGGGR..GGEA.....EGGRPGDSSL.EERTFRILGLPAPEVNLRDAP....TQPGSPEHQALGPAASGAQGRA.EGSE.VAMV.QRRAG.......RGWARTPGPYAGALREAVSRIRRHTAPDSDTDEA.EELSVHSGSSDGSDTEAPGASWRNERTLPGVGNS..SPEEDGKTAELSDSVGEILDVISQTEEVLFGVRDIRGTQQANRK...........................
H2NH62_PONAB/55-710                  ............................................................................................................MDFQASHWVRGFQNRTCGPRPGSPQPPPRRPWASRVLQEATNWRAGPLAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNAPRAAQLAGLPAPLRPERLAPVGRAPRP...SAQPQSDPG.SAWAGPWGGRRPGPPSYEAHLLLRGSAGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPGHSQVPISSAPAAT...PARTEGGRTKKRLDPRIYRDVLGAWGLRQGQGLLGGSPGCGAARARPEP.GKGVVEKSLGLAAADLNSGSHSHPQAKA.TGSAGTEIAPAGSATAAPCAPRPAPRSRHHLKGSREGKEG.REQIWFPKCWIPSPK....KQPPRHSQ.TLPRPWAP.GGTGWRESLGLGEG....AGPETLEGWKAT....RRAHTLPRSSQG......PSR.GEGVFVIDATCVVIRSQYVPTPGTQQVQLLPSGVTRVVGDSPSQSKP.GKEEGEGATVFPSPCQKRLSSSRLLHQPGGGR..GGEA.....EEGRPGDSSL.EERTSRILGLPAPEVNLRDAP....TQPGSPEHQALGPAASGAQGRA.EGSE.VAVV.QRRAG.......RGWARTPGPYAGALREAVSRIRRHTAPDSDTDEA.EELSVHSGSSDGSDTEAPGASWRNERTLPGVGNS..SPEEDGKTAELSDSVGEILDVISQTEEVLFGVRDIRGTQQGNRK...........................
L8Y728_TUPCH/153-533                 ............................................................................................................----------------------------------------------------------------------------------..------......-----------------------------------...---------.-------------------------AAQCAPRR.RWARPPPYVAPPSYEGPHRTL.GTKRGPAPSQPPTSSAPAVT...PARTEGGRSKKRLDPRIYRDVLGAWGLRQGRGLLGGSSGCGATRARPES.CKGAAEKSRRLATASLNNGSDGYSQAKA.TANPSRETAPSGSATATPSSPRPAPRSRHHLKSSREGKEG.REPIWIPKCWIPSPK....KQPPQHSQ.TLPRPWAP.GGTGWTESLGHRDR....AGPETPEGWKAT....RRAHTLPRSSRG......PAR.GEGVFVIDATRVVIRSQYVPTPQTQQVHLLPSGVPRTVGDAPSPPKP.QK-EGEEAVVFPSPYQKLLVNSRLLPQPGLGR..GYEA.....EGAKPGDSSL.EERASRILGLPVGEVNLRDTP....AQLGSPEHPALGPAALGSAGTA.EGQE.VA--.-----.......----------------------------------.----------------------------------..--------------------------------------------gd.........................
A0A096N5Z4_PAPAN/123-778             ............................................................................................................MDFQASHWARGFQNRTCGPRPGSPQPPPRRPWASRVLQEATNWRAGPLAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNAPRAAQPAGLPATLRPERLALVGRAPRP...SAQPQSDPG.SAWAGPWGGRRPGPPSYEAHLLLRGSAGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPGHSQVPTSSAPPPT...PARTEGGRTKKRLDPRIYRDVLGAWGLRQGQGLLGGSPGCGAARARPEP.GKGVVEKSLGLAAADLNSGSDSHPQAKA.TGSAGTETTPAGSATAAPSAPRPAPRSRHHLKGSREGKEG.KEQIWFPKCWIPSPK....KQPPRHSQ.TLPRPWAP.GGTGWRESLGLGEG....AGPETLEGWKAT....RRAHTLPRSSQG......PSR.GEGVFVIDATCVVIRSQYVPTPRTQQVQLLPSGVTRVVGESASQSKP.GKEESEGATVFPSPCRKRLSNSRLLHQPGGGR..GGEA.....EGGRPGDSSL.EERTSRILGLPAPEVNLRDAP....TQPGSPEHQALGPGASGAQGRA.EGSE.VAVI.QRRAG.......QGWARTPGPYAGALREAVSRIRRHTAPDSDTDEA.EELSVHSGSSDGSDTEAPGASWRNERTLPGVGNS..SPEEDGKTAELSDSVGEILDVISQTEEVLFGVRDIRGTQQGNRK...........................
M3YTF1_MUSPF/55-701                  ............................................................................................................MDFQASHWARGPQSRTCGPRPGSPEPPPRRPWASRVLQEATNWRAGPPAEARAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNAPRVAQPVGPPAPSRPERLGPAGRPPRP...SAQPQSDPG.AAWAGPWGGRRPGPPSYEAHLLLRGAAGTALRR.RWDRPPPYVAPPSYEGPHRTL.GSKRGPEPSQAPASAASAPI...PAGTEGGCTKKRLDPRIYRDVLGAWGLRQGRGLLGGSPGCGTAGPRLESlGKGAAEKSLGLAT----SGSDGHSQAKA.AVNPSTETAPAGLAAATPSPPRPAPRSRPHLKGSGEGKEN.REQSWLPKCWIPSLK....KQPPRHSQ.TLPRPWAP.GGTGWRESLGHREG....ARPGTLEGWKGT....RRAHTLPRSSRG......PAR.GEGVFVIDATCVVIRSQYVPTPRTQHVQLLPDGVPRVVGDAPNQSKP.NKEEGEGAAAFPSPCQKRLLSSRLSHHLGGGH..GFEA.....EGGKPADSSL.EERASRILGLPVGEVNLQDAP....PQSGSPERSASGPAASGGTVGA.EGSEeGAAV.PRRAG.......RGWPRTPGPYAGALREAVSRIRRHTAPDSDSDEA.AELSVHSGSSDGSDTEASGASWRNEQPRPG----..---EGGKTAELSDSIREILDVISRTEEAFFGTRDTKGTPQGNRE...........................
I3N3B4_ICTTR/55-709                  ............................................................................................................MDFQASHWARGPQNRTCRPSPGSPEPPPRRPWASRVLQEATNWRAGPPAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPVGQ......PRLEPRNVPRVAQPAGLPVPSRPGRLGQVGRA-RP...SAQPQSDPG.APWAGPWGGRRPGPPSYETHLLLRGSAGTAPRR.RWDRPPPYVAPPCYEGPHRTL.GTKRGPEFSQAPISSAPTPT...PARTEGGRTKKKLDPRIYRDVLGAWGIRQGRGLLGGSPGCGEARARPES.DKGATEKSLGLAAAGLNNGSDRHSQAKT.TGSPGTEIAPSRSATASPSPPRPAPRSRHHYKGSREGKEG.REPIWLPKCWFPSPK....KQSPRHSQ.TLPRPWAP.GGTGWKEFLGPREG....TGSETLEGWKAT....RRAHTLPRSSRG......PAS.GEGVFVIDATCVVIRSQYVPTSRTQKVQPLPSGEPRVVGEAPRQPNP.CKEEGEGSEVFPSSDQKPLLSSLLLHQLGRGR..GGET.....EDGKPGESSL.EERASRILGLSVGEVNLPDAP....TQPGSPEHPTLGPSALGGAGGA.KGLE.VAVV.PRRAG.......GGWARTPGPYAGALREAVSRIRRHTAPDSDSDEA.EELSIHSGSSDGSDTETPGASWRNERTLSVVGNA..RPREGGKTAELSDSVQEILDVISQTEQALFGARDAKGTPQGNRE...........................
G1SV31_RABIT/42-693                  ..........................................................................................................ts---RSSHWARGPRSRTCRPRPGSPEPSPRRPWASRVLQEATNWRAGPPAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGQ......PRPEPRNAPRAVQPAGLSGPSRRERLGPAGRAARP...SAPPHSETG.AAWAGPWGGRRPGPPSYEAHLLLRGAAATAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRSPERSQASAASAPAPT...PARTEGGSARKRLDPRIYRDVLGAWGLRQGRGLLGGSPGCGAVRARPAS.GKGAAERGPVLPAAGLHGGSDRRFQATAvAGSPGSGTAPARPAAAPSSPPRPAPRSRHQLEGSREGKEGrREQVWLPRCWMLSPK....KQPSRQSQ.TLPRPWAP.GGTGWRESPGHGDG....PGPA-------A....RRAHTLPRCSRR......PAG.GEGVFVIDATCVVIRSQYVPTPRAQQVQLLPSEMVRVVGDAPSPPKP.GPQQGEGASGSPFRVPRPQLVS-LSHRPGEGSegEGEA.....EGGKPGDSSSlEERASRILGLPVGEVNLRGAP....AQSGRPEHPALGPAAPAGAGCA.RGSG.GAAG.PRRAG.......GGWARAPGPYAGALREAVSRIRRHTAPDSDSDEA.EELSAHSGSSDGSDTEAPRASWRNEMTQPAAGNP..GPQEGGKRTEMSDSFRELLGAVSQTEEALFGARDPAETPQADRE...........................
G5AU33_HETGA/125-647                 ...........................................................................................................x----------------------------------------------------------------------------------..------......-----------------------------------...---------.-VWAGPWRGRRPGPPSYEAHLLLRGAAGTAPRR.RWDQPPPYVAPPSFEWPHRTL.GTKRGPQLSQVPTSSAPAPT...PARTEGGRAKKRLDPRIYRDVLGAWGLRPGRGLLGGSPGCAPARPRPES.GKGSSKKSSGLAAAGLNSGRGSRSQADA.PGGPGTETAPAGSTPATPRSPRPAPRSGHHLKGSREGKEG.REHIWLPKCWIPSPK....KQPPHRSQ.TLPRPWAP.GGTGWREFPGQREG....EGPEALGGWKAT....RRAHTLPRSSRA......PAP.GEGIFVIDATCVVIRSQYVPAPRTQQVQLLPSGESRIVGHGPGQPKG.SKEEGERALGFPSACQKLLLSSRLLHQPSAGH..GCKA.....KGGKPEDSSL.EERASPVLGLLVGEVTLPCAA....VPPGIPERAASGPAAPADAGSV.RGSK.LAAA.PRPVG.......GGWARTPGPYAGALREAVSRIRRHTAPDSDSDEG.-ELSIHSGSSDGSDTEAPGASWRNERTLPVAGDS..QPGEGGKTAELNSSIREILDVISQTEQALFPARDTKGTPQGSRE...........................
S9YFK7_9CETA/439-511                 ..........................................................................................................lp----------------------------------------------------------------------------------..------......-----------------------------------...---------.---------------------------------.---------------------.--------------------...-------------------------------------------------.----------------------------.----------------------------------------.---------------....--------.--------.--------------....------------....------------......---.-----------------------------------------------.--------------------------------..----.....----------.---------------------....----------------------.----.----.-----.......---------------------------------A.AELSVHSGSSDGSDTEPPGAAWRNERIGPQ----..---EGGK-TELSDNIRDSLDVISRTEEVLFGARDTKGTPQGNRE...........................
A0A091DMT6_FUKDA/138-222             ...........................................................................................................s----------------------------------------------------------------------------------..------......-----------------------------------...---------.---------------------------------.---------------------.--------------------...-------------------------------------------------.----------------------------.----------------------------------------.---------------....--------.--------.--------------....------------....------------......---.-----------------------------------------------.--------------------------------..----.....----------.---------------------....----------------------.----.----.-----.......--------------------------PHSDSDGG.EELSVHSGSSDGSDAEAPGASWRNERTPPVAGDT..PPGEGVNTAELKGSDREILDVISQTEQALFPARDTKGTPPG---k..........................
H2Q5U5_PANTR/55-708                  ............................................................................................................MDFQASHWARGFQNRTCGPRPGSPQPPPRRPWASRVLQEATNWRAGPLAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNAPRVAQLAGLPAPLRPERLAPVGRAPRP...SAQPQSDPG.SAWAGPWGGRRPGPPSYEAHLLLRGSAGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPGNSQVPASSAPAAT...PARTEGGRTKKRLDPRIYRDVLGAWGLRQGQGLLGGSPGCGAARARPEP.GKGVVEKSLGLAAADLNSGSDSHPQAKA.TGSAGTEIAPAGSATAAPCAPRPAPRSRHHLTGSREGKEG.REQIWFPKCWIPSPK....KQPPRHSQ.TLPRPWAP.GGTGWRESLGLGEG....AGPETLEGWKAT....RRAHTLPRSSQG......LSR.GEGVFVIDA-CVVIRSQYV-TPRTQQVQLLPSGVTRVVGDSPSQSKP.GKEEGEGATVFPSPCQKRLSSSRLLHQPGGGR..GGEA.....EGGRPGDSSL.EERTFRILGLPAPEVNLRDAP....TQPGSPEHQALGPAASGAQGRA.EGSE.VAVV.QRRAG.......RGWARTPGPYAGALREAVSRIRRHTAPDSDTDEA.EELSVHSGSSDGSDTEAPGASWRNERTLPGVGNS..SPEEDGKTAELSDSVGEILDVISQTEEVLFGVRDIRGTQQGNRK...........................
H0UZS0_CAVPO/1-650                   ............................................................................................................MDFQASHWAPGSQSRTCRPRPGSPEPPPRRPWASRVLQEATN-------EVRAREQEKRKAASQEREAKETERKRRKAGGPR..RSPLGQ......SRQEPRNALRAAHPAGLSAPPRPERFGQVGRAPRP...PAQPQSDPG.AVWAGSWAGRRPGPPSYEAHLLLRGAAGTAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPERSQGPTSSAPAPT...PARTEGGRAKKRLDPRIYRDVLGAWGLRQGRGLLGGSPGCAAAKPRLEF.SKGGAEKSPGLATAALNSGSDSHFQADV.PSSPGTEIALAGPVPATTSPPRTAPRFRHQLQGSREGKEG.RERIWLPKCWIPSPK....KQPPRHSQ.TLPRPWAP.GGTGWRESLGQREG....VGPEALEDWKET....RRPHTLPRSSRG......LAR.GEGVFVIDATCVVIRSQYVPTPRTQQVQLLPSGESRVVGDGPRQPNG.SKEEGERASVFSSACQKLLLSSRVLHQPSGEP..RCEA.....EGGKAEDSSHgGARGPHLWDSRAGEVHVPCAA....AQPASPEHAASGAAAPADAGSV.RGSK.VTAA.PRRAG.......GGWARTPGPYAGALREAVSRIRRHTAPDSDSDEGeEELSVHSGSSDGSDTEAPGASWWSERTPPETGGT..SPGEGGKTAELK-SIRETLDAISQPEQALFPTRDTNGTPQGHRK...........................
G1S849_NOMLE/55-284                  ............................................................................................................MDFQASHWARGFQNRTCGPRPGSPQPPPRRPWASRVLQEATNWRAGPLAEVRAREQEKRKAASQEREAKETERKRRKAGGAR..RSPPGR......PRPEPRNAPRAAQLAGLPAPLRPERLAPVGRAPRP...SAQPQSDPG.SAWAGPWGGRRPGPPSYEAHLLLRGSAGTALRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPGHSQVPTSSAPAPN...PARTEGGRTKKRLDPRIYRDK----------------------------.----------------------------.----------------------------------------.---------------....--------.--------.--------------....------------....------------......---.-----------------------------------------------.--------------------------------..----.....----------.---------------------....----------------------.----.----.-----.......----------------------------------.----------------------------------..--------------------------------------------egn........................
G3I6J1_CRIGR/1-358                   ............................................................................................................----------------------------------------------------------------------------------..------......-----------------------------------...---------.---------------------MLRGAAGSAPRR.RWDRPPPYVAPPSYEGPHRTL.GTKRGPELSRASTSSAPVPA...TARTEGGRTKKRLDPRIYRDVLGAWGLRQGRGLLGGAPGCAAARAGSES.CKGAIEKSSGLAAAGLNSGGYSHPQAKA.TGSPDTEAAPAGST--IHSPPCPAPRSRQHLKGSREGKEG.SEHIWLPKCWLSSPK....KPPVRHSQ.TLPRPWAP.GGTGWRESLGQREG....TEHETLEVWKAT....RRAHTLPRSSRG......PSR.RDGIFVIDATCVVIKSQYVPTPRTQQVQRLPSREPSIVSDSPRQPKP.CQEEGEGVTANPSACQKLPLSSGISNQAGGGS..ECEA.....ERGEQGDSTR.EDRTSRILGFPVGEVTLRDVV....----------------------.----.----.-----.......----------------------------------.----------------------------------..--------------------------------------------htqp.......................
G1KYY8_ANOCA/164-409                 ...........................................................................................ppqhtlpvgwgfshavg----------------------------------------------------------------------------------..------......-----------------------------------...---------.---------------------------------.---------------------.--------------------...-------------------------------------------------.----------------------------.----------------------------------------.---------------....--------.-----WLP.GDVRDGGSK-VGDK....HSRSILPKWKEP....SHARD-PGGSQGslsklvPQK.RGGLFVIDATCVVIQAHYIPAPRTERVRYLGQEGLDKVKAPLSPGPV.APASMEERAAR---ILGLSVSELGFAEAGKGK..NVGA.....EMPEQKVNAG.STANLAMPKDICGTGQHKGAP....SPPASPREKTITPTESGCAQPQ.G-KE.EPE-.PEPVF.......SPLSR---SYALDLKEAMSRIRRHTAPDSDTDEE.LE--------------------------------..--------------------------------------------kdch.......................
G5AU33_HETGA/56-126                  ............................................................................................................MDFQASLWARGSQSRTCRPRPGSPEQPPRRPWASRVLQEATNWRAGPPAEVRAREQEKRKAASQEQEAKX------------..------......-----------------------------------...---------.---------------------------------.---------------------.--------------------...-------------------------------------------------.----------------------------.----------------------------------------.---------------....--------.--------.--------------....------------....------------......---.-----------------------------------------------.--------------------------------..----.....----------.---------------------....----------------------.----.----.-----.......----------------------------------.----------------------------------..--------------------------------------------v..........................
#=GC seq_cons                        ............................................................................................................MD.QuShWsRt.QsRTCt.RPGSPpPPPRRPWASRVLQEATNWRuG..AEsRAREQEKRKAASQEREAKETERKRRKAGGAR..RSP.Gp......sR.E.RNs.Rssp.hh..h....thhs.hh.s.Rs........t..G.ssWAGsWsGRRsGPPSYEAHLLLRGuAGsAPRR.RWDRPPPYVAPPSYEGPHRTL.GoKRGPt.SpsPsuuAssss...ssRTEGGpsKKRLDPRIYRDVLGAWGLRQGpGLLGGuPGCussts+.E..sKGssE+S.tlssAs.psusttp.Qucs.sutsssthh.ut.s..hsssP+PsPRuR.phpGStcG+Es.tEp.WhPcsWlsS.K....+.ss+pSQ.TLPRPWAP.GGTGW+EShG.t-t....st.-sLpsWKsT....RRAHTLPRSSpu.......ut.tEGlFVIDATCVVIRSQYVPTPRTQpVQLLPuG.sRslu-uss.sKP.scEEuEtssshPSsCQKh..uSpl.pQ.utGp..thEA.....EuGcssDSSL.EERss+lLGhPssEVNLpcsP....spPGoPE+.slGPuAsuststs.cGsc.ssss..R.sG.......tuWuRsPGPYAGALREAVSRIRRHTAPDSDoDEA.tELSlHSGSSDGSDTEAsGASWRsEpshPt.........EsGKsAELssshtEllDVlSpTEpshh.hcD.pts.QupRc...........................
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