GenomeNet

Database: Pfam
Entry: Dynactin_p22
LinkDB: Dynactin_p22
Original site: Dynactin_p22 
#=GF ID   Dynactin_p22
#=GF AC   PF07426.6
#=GF DE   Dynactin subunit p22
#=GF AU   Vella Briffa B
#=GF SE   Pfam-B_21336 (release 10.0)
#=GF GA   21.50 21.50;
#=GF TC   22.00 21.70;
#=GF NC   20.90 21.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Dynactin
#=GF RN   [1]
#=GF RM   9722614
#=GF RT   Characterization of the p22 subunit of dynactin reveals the
#=GF RT   localization of cytoplasmic dynein and dynactin to the midbody
#=GF RT   of dividing cells. 
#=GF RA   Karki S, LaMonte B, Holzbaur EL; 
#=GF RL   J Cell Biol 1998;142:1023-1034.
#=GF DR   INTERPRO; IPR009991;
#=GF CC   This family contains p22, the smallest subunit of dynactin, a
#=GF CC   complex that binds to cytoplasmic dynein and is a required
#=GF CC   activator for cytoplasmic dynein-mediated vesicular transport.
#=GF CC   Dynactin localises to the cleavage furrow and to the midbodies
#=GF CC   of dividing cells, suggesting that it may function in
#=GF CC   cytokinesis [1]. Family members are approximately 170 residues
#=GF CC   long.
#=GF SQ   123
#=GS G5B061_HETGA/1-172    AC G5B061.1
#=GS H2YTE0_CIOSA/1-169    AC H2YTE0.1
#=GS A7RWD0_NEMVE/2-177    AC A7RWD0.1
#=GS B4J4S0_DROGR/1-166    AC B4J4S0.1
#=GS I1BNJ4_RHIO9/1-178    AC I1BNJ4.1
#=GS Q4T0D5_TETNG/1-185    AC Q4T0D5.1
#=GS E2A705_CAMFO/1-174    AC E2A705.1
#=GS B3RP31_TRIAD/2-172    AC B3RP31.1
#=GS D3BAQ0_POLPA/91-235   AC D3BAQ0.1
#=GS H2MLP3_ORYLA/2-175    AC H2MLP3.1
#=GS H3CI60_TETNG/1-173    AC H3CI60.1
#=GS F4WCY9_ACREC/1-174    AC F4WCY9.1
#=GS D6WMQ4_TRICA/1-172    AC D6WMQ4.1
#=GS H2MLP2_ORYLA/1-174    AC H2MLP2.1
#=GS H9HRI7_ATTCE/1-174    AC H9HRI7.1
#=GS F1NH38_CHICK/1-117    AC F1NH38.1
#=GS G3UV58_MELGA/1-172    AC G3UV58.1
#=GS B4QI48_DROSI/1-161    AC B4QI48.1
#=GS C1BYT5_ESOLU/1-174    AC C1BYT5.1
#=GS C1BL28_OSMMO/1-174    AC C1BL28.1
#=GS H9KN22_APIME/1-173    AC H9KN22.1
#=GS H0WY21_OTOGA/1-172    AC H0WY21.1
#=GS D3PH51_9MAXI/1-174    AC D3PH51.1
#=GS I1GCY8_AMPQE/9-182    AC I1GCY8.1
#=GS G1SD49_RABIT/1-172    AC G1SD49.1
#=GS DCTN3_HUMAN/1-172     AC O75935.1
#=GS F4QEE8_DICFS/101-252  AC F4QEE8.1
#=GS H9F5T1_MACMU/1-139    AC H9F5T1.1
#=GS Q5T1I6_HUMAN/1-117    AC Q5T1I6.1
#=GS H9GTI7_ANOCA/1-36     AC H9GTI7.1
#=GS Q8NB28_HUMAN/1-117    AC Q8NB28.1
#=GS G3NAA4_GASAC/2-175    AC G3NAA4.1
#=GS G5BUY4_HETGA/38-74    AC G5BUY4.1
#=GS G3WYV2_SARHA/1-172    AC G3WYV2.1
#=GS B9EQ42_SALSA/1-174    AC B9EQ42.1
#=GS A0AQB7_DROME/1-160    AC A0AQB7.1
#=GS B4MNL6_DROWI/1-162    AC B4MNL6.1
#=GS B3MF26_DROAN/1-161    AC B3MF26.1
#=GS B5G3H2_TAEGU/1-171    AC B5G3H2.1
#=GS E2RBC1_CANFA/1-172    AC E2RBC1.1
#=GS E5SM01_TRISP/139-283  AC E5SM01.1
#=GS E4YH01_OIKDI/1-156    AC E4YH01.1
#=GS G4VHB1_SCHMA/1-128    AC G4VHB1.1
#=GS B4LK37_DROVI/1-170    AC B4LK37.1
#=GS E2C7L9_HARSA/1-174    AC E2C7L9.1
#=GS F2U056_SALS5/1-97     AC F2U056.1
#=GS B5G3H3_TAEGU/1-171    AC B5G3H3.1
#=GS A0AQB0_DROME/1-161    AC A0AQB0.1
#=GS G3USF6_MELGA/1-171    AC G3USF6.1
#=GS Q5ZK19_CHICK/1-171    AC Q5ZK19.1
#=GS H0UWG1_CAVPO/1-172    AC H0UWG1.1
#=GS G1PY14_MYOLU/1-137    AC G1PY14.1
#=GS Q6GQL6_DANRE/1-174    AC Q6GQL6.1
#=GS F7E9Z7_MONDO/1-83     AC F7E9Z7.1
#=GS G1Q0J6_MYOLU/1-95     AC G1Q0J6.1
#=GS Q54ZI7_DICDI/104-227  AC Q54ZI7.1
#=GS F6WBC9_CALJA/1-172    AC F6WBC9.1
#=GS H2ZSA3_LATCH/1-173    AC H2ZSA3.1
#=GS E3XCQ6_ANODA/1-163    AC E3XCQ6.1
#=GS Q5DD70_SCHJA/1-176    AC Q5DD70.1
#=GS Q0C775_AEDAE/2-162    AC Q0C775.1
#=GS B4KM29_DROMO/1-162    AC B4KM29.1
#=GS B0X536_CULQU/3-170    AC B0X536.1
#=GS G1QY83_NOMLE/1-172    AC G1QY83.1
#=GS H3JEL1_STRPU/2-147    AC H3JEL1.1
#=GS G1M7R7_AILME/2-173    AC G1M7R7.1
#=GS B4I8F7_DROSE/1-161    AC B4I8F7.1
#=GS H2PUL4_PONAB/1-172    AC H2PUL4.1
#=GS DCTN3_MOUSE/1-172     AC Q9Z0Y1.2
#=GS G3HN24_CRIGR/279-379  AC G3HN24.1
#=GS B9EMM5_SALSA/1-174    AC B9EMM5.1
#=GS E9I852_SOLIN/11-187   AC E9I852.1
#=GS Q86E07_SCHJA/1-128    AC Q86E07.1
#=GS E9QB54_DANRE/1-167    AC E9QB54.1
#=GS F7G8T6_MONDO/1-172    AC F7G8T6.1
#=GS E0VZI7_PEDHC/1-175    AC E0VZI7.1
#=GS Q6NTU2_XENLA/1-168    AC Q6NTU2.1
#=GS G3UU08_MELGA/1-171    AC G3UU08.1
#=GS F7HC42_MACMU/1-90     AC F7HC42.1
#=GS D2I3E6_AILME/1-172    AC D2I3E6.1
#=GS Q8I1F8_DROER/1-159    AC Q8I1F8.1
#=GS E9H327_DAPPU/1-171    AC E9H327.1
#=GS G3NAA1_GASAC/1-174    AC G3NAA1.1
#=GS F8W786_HUMAN/1-117    AC F8W786.1
#=GS F7HA44_MACMU/1-100    AC F7HA44.1
#=GS F1A3B2_DICPU/60-219   AC F1A3B2.1
#=GS C1BNV1_9MAXI/1-173    AC C1BNV1.1
#=GS DCTN3_BOVIN/1-172     AC Q0P5A1.1
#=GS B7Q631_IXOSC/9-182    AC B7Q631.1
#=GS H2ZSA2_LATCH/1-164    AC H2ZSA2.1
#=GS C3XR47_BRAFL/1-172    AC C3XR47.1
#=GS Q292H9_DROPS/1-155    AC Q292H9.1
#=GS G3TJS5_LOXAF/1-172    AC G3TJS5.1
#=GS B4GDG4_DROPE/1-158    AC B4GDG4.1
#=GS H2QX67_PANTR/1-172    AC H2QX67.1
#=GS F7HC42_MACMU/88-144   AC F7HC42.1
#=GS Q9W1V8_DROME/1-161    AC Q9W1V8.1
#=GS D4A1B8_RAT/1-172      AC D4A1B8.1
#=GS G7NFL4_MACMU/1-172    AC G7NFL4.1
#=GS F6W1Z3_CIOIN/1-170    AC F6W1Z3.1
#=GS G7PS31_MACFA/1-172    AC G7PS31.1
#=GS G4Z2G4_PHYSP/77-172   AC G4Z2G4.1
#=GS A4IIY6_XENTR/1-168    AC A4IIY6.1
#=GS G6DKN2_DANPL/1-172    AC G6DKN2.1
#=GS E9Q919_MOUSE/1-149    AC E9Q919.1
#=GS G1NWU1_MYOLU/1-172    AC G1NWU1.1
#=GS Q6NTT9_XENLA/1-168    AC Q6NTT9.1
#=GS H9J1G0_BOMMO/1-172    AC H9J1G0.1
#=GS F1SEC0_PIG/1-172      AC F1SEC0.1
#=GS F6ZVN7_HORSE/1-172    AC F6ZVN7.1
#=GS H2RKX5_TAKRU/2-175    AC H2RKX5.1
#=GS B5G3H5_TAEGU/1-52     AC B5G3H5.1
#=GS F7E9Z7_MONDO/82-137   AC F7E9Z7.1
#=GS C1BI38_ONCMY/1-174    AC C1BI38.1
#=GS B9EP16_SALSA/1-174    AC B9EP16.1
#=GS B5G3H6_TAEGU/1-56     AC B5G3H6.1
#=GS Q4QR40_XENLA/1-166    AC Q4QR40.1
#=GS B4P919_DROYA/1-160    AC B4P919.1
#=GS A0AQB1_DROME/1-160    AC A0AQB1.1
#=GS F7HC36_MACMU/1-162    AC F7HC36.1
#=GS F7BRF6_XENTR/1-57     AC F7BRF6.1
#=GS G3QK97_GORGO/1-172    AC G3QK97.1
#=GS F8UU20_AILME/1-172    AC F8UU20.1
G5B061_HETGA/1-172               .................................................m-AALTDVQRLQAQVEELERWV.......Y.G...-.-P..V.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVDALVPMLDSAS.I.KAVHEHA.TRLQHLAQIHIQQQDQCMEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
H2YTE0_CIOSA/1-169               ..................................................MSEENLLANLEERIAQLEERC.......L.P...E.DG..N.--....-....-...D..K...S...L.LA.GLN.......KVNRML...TS-..ATDRERFK...E...VFSK..VPQI.TE.YLSPG...Y.IDSI.SMNTQC.EKEAILASEHNIRK...........SHELFAEIDQLSKVLNIQE.L.QDVPNFT.KRIGTLEQTQLKQLESMNSISEDFQALLLAYNQLVSSLSENFVHWDWV-l................................
A7RWD0_NEMVE/2-177               ............................................adsrae-----GIAALEKRISELEIRA.......LsN...E.ED..L.KC....F....Q...N..E...S...C.LS.TVA.......HVQQEL...KRL..SSKYSRVA...E...AWKK..VKEL.ET.FLSPE...F.VEGA.TLSDDV.KADIIITGENKLIS...........CTEKLSEIEDLNKIVNTEH.L.KDLPVWC.AKMEPLIQVQIKQQEHVGEMNERLTNLLSCYNNIITTLSKQFIEWDAL-l................................
B4J4S0_DROGR/1-166               ................................................me-----ALDILEKRIDALTRVL.......-.GplpE.QH..V.GD....GdcnpK...T..A...N...I.VD.SLC.......SANALL...SEA..TTGRSQLQ...Q...CVGR..AAEL.EK.YLDPN...Y.LEEQ.QQVRS-.KEVYLNAVAPELYA...........QSEQLERVKQLEPALGAEY.F.RSIPSEC.--LDKLKQITENN------------------------------------geyaqqselieeslilamkrygeiqagl.....
I1BNJ4_RHIO9/1-178               .............................................mdehg---------FEARLRHLEYIL.......Y.G...Q.QQ..Q.QN....K....S...T..N...E...ViIK.RME.......LLRKEL...SSI..YQNNKSIK...Y...FIEKcnLDDThSK.LLNPNtstYsLERE.LLSTDV.KIELLLAAQDDLKK...........FAQEVKQVKSLEHVVSGTE.L.EVVDKLK.PQLSSMDVIHVNQTKQLNQLTKEISDLMERYNKTVNTVSEIFIAWDNIL.................................
Q4T0D5_TETNG/1-185               ..................................................MDRNLAMDNLEMRLQVLESRI.......Y.G...E.KR..S.KS....A....K...P..V...K...C.AE.SLA.......RIQAGL...IST..GNKRERVK...I...LHKK..IEDL.LK.YLDPQ...F.TDHI.ALPDAM.KLEFILAENKIVDCvspqrrtscfpQAALLEQISSMQPLLDSSY.V.RDVPEHA.TKLQRLSQIHVRQQDQMEVQSQEVKKLFEEYNKMMFLLSKQFTQWDEAL.................................
E2A705_CAMFO/1-174               ................................................ms-----SVKLLEDRIANLEKQV.......Y.G...L.GK..T.IS...iD....DpvpP..N...A...I.IE.RLL.......DVNSLL...SSA..LSGREKPN...A...LIKR..LPEL.NG.YLEPV...-.PEGF.DIPISA.KAQLLLTMEPEIIE...........NDKLLTKVQELAPILESER.I.KNVPELN.STFNKISLSYLKAYEDSKELSTHIHDLLSKYNAVISSISESLITLD---aav..............................
B3RP31_TRIAD/2-172               ........................................sddqtaidws--------LLDKRIEELEYLV.......Y.K...A.KD..G.KV....A....E...R..R...RfksV.AD.GIY.......IVQDRL...NRS..RSGKTNIK...H...VWQQ..LEFL.HK.IISSE...F.FDEL.TVTDEV.KREIILASETYFRD...........ISEHLEEIKSLEEFINSDI.W.KNVPDQI.EKFRALQEIFAKQQDETEHLSEQVQELLINYNSA---------------vskqqit..........................
D3BAQ0_POLPA/91-235              ........................................ipletlvdqi---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.--D.......RFKSTL...QHI..KSDHESINqfmT...LYKE..NEKL.FS.EIA--...E.NDEL.LTP-VE.KLSIILSAEDEIIY...........TANYLQKIAELEKFINPTT.L.ESIPSMI.TQLQPIESLHNEQQAITIALNKKLESRIQSYNDIIESLSMKFAYWDKVL.................................
H2MLP3_ORYLA/2-175               ..................................................MDKTLETESLEMRIEALENQI.......N.G...E.RR..I.RS....G....K...Q..V...K...C.AE.SLA.......RIQSAL...TNT..ANKRERVK...I...LHKK..IEDL.MK.YLDPQ...F.TDHI.TVPDTI.KLEFILAEEDSLLS...........QAALLEQVSSLQPLLDSTY.I.RDVPEHA.TKLHRLSQIHIKEQDQTEAQSQEVKKLFEEYNKMMFLLSKQFTQWDESL.................................
H3CI60_TETNG/1-173               ..................................................MDRNLAMDNLEMRLQVLESRI.......Y.G...E.KR..S.KS....A....K...P..V...K...C.AE.SLA.......RIQAGL...IST..GNKRERVK...I...LHKK..IEDL.LK.YLDPQ...F.TDHI.ALPDAM.KLEFILAEEDFLL-...........QAALLEQISSMQPLLDSSY.V.RDVPEHA.TKLQRLSQIHVRQQDQMEVQSQEVKKLFEEYNKMMFLLSKQFTQWDEAL.................................
F4WCY9_ACREC/1-174               ................................................ms-----SVKLLEERIANLEKQV.......Y.G...L.GK..M.MNiddpA....P...P..N...A...I.ID.RLT.......DVNSLI...SSA..LSGREKPN...A...LIKR..LPEL.NG.YLEPT...C.ED-V.DIPTSA.KAQLLLTMEPEIIE...........NHKLLNKVQELMPVLESER.I.KDAPELN.NTLNKLSLSYLEAYEDSKELDAHVHDLLSKYNAVINSISESLIILDNT-v................................
D6WMQ4_TRICA/1-172               ................................................md-----SLDVLEKRIAALELQV.......L.P...K.NPnfA.SD....D....K...T..Q...E...I.TH.LLL.......LTQTMI...SSA..LSCREAIT...S...ILQH..MTTI.NE.YLDPS...N.GEN-.ELEVEA.KRHYLLELYPELKD...........TVKLISTFESLTPYTDSSS.I.IKVTELT.DKLESLAVSNLKIFEESQEVTKKTVSALQQYNDIISTIKVLFSQLDKA-i................................
H2MLP2_ORYLA/1-174               ..................................................MDKTLETESLEMRIEALENQI.......N.G...E.RR..I.RS....G....K...Q..V...K...C.AE.SLA.......RIQSAL...TNT..ANKRERVK...I...LHKK..IEDL.MK.YLDPQ...F.TDHI.TVPDTI.KLEFILAEEDSLLS...........QAALLEQVSSLQPLLDSTY.I.RDVPEHA.TKLHRLSQIHIKEQDQTEAQSQEVKKLFEEYNKMMFLLSKQFTQWDESL.................................
H9HRI7_ATTCE/1-174               ................................................ms-----SVKLLEERIANLEKQV.......Y.G...L.GK..M.MN...iD....Dp.aP..S...N..vI.ID.RLT.......DVNSLI...SSA..LSGREKPN...A...LIKR..LPEL.NG.YLEPT...C.ED-V.DMPTSA.KAQLLLTMEPEIVE...........NYKLLNKVQELMPMLESER.I.KDAPELN.NTLNKLSLLYLEAYEDSKELDAHVHDLLSKYNAVINSISESLIILDN--av...............................
F1NH38_CHICK/1-117               ................................................lf---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.---.......------...---..--------...-...-FAL..VEDV.IK.YLDPQ...Y.IDRM.AVPDTM.KLQFILAEEQALPS...........RVALLEQVKNLEPVLDSAS.I.QAAPEHA.AKLQRLSQIQIQQQEQCEQFTDEVKMLLENYNKTTLLLSKQFVQWNEIL.................................
G3UV58_MELGA/1-172               ................................................ma-AEMAALQQLHWRLEELEQRV.......-.-...-.-G..V.GA....C....E...P..S...K..qV.AD.ELV.......RVQLAL...SNI..AGKRERIK...I...LFKK..IEDV.IK.YLDPQ...Y.IDRM.AVPDTM.KLQFILAEEQALPS...........RVALLEQVKNLEPVLDSAS.I.QAAPEHA.TKLQRLSQIQIQQQQTCCFPSEASKAWMLKRNIQTLLLSKQFVQWNEIL.................................
B4QI48_DROSI/1-161               .................................................m----EALDILEKRIDALTRVL.......-.G...-.PG..Q.DS....E....V...G..E...G...V.VD.ALC.......SAHALL...GEA..TTGSAALQ...Q...CVKR..SDEL.EK.YLDPN...F.LEEH.QQVRS-.KEVYLHAVAPELHT...........QAEQLERIKQLEPALGAEY.F.RSIPAEClEQLKGITQNNGEYAQQSELIEES--------------------------lvlamkrygeiqagllss...............
C1BYT5_ESOLU/1-174               ..................................................MDKKIEVDNLEMRLDTLESRI.......Y.G...E.RR..N.KG....G....K...P..V...K...C.TD.SLS.......RIQVAL...ANT..ANKRERVK...I...LHKK..IEDL.LK.YLDPQ...F.TDHI.TVPDSM.KLEFILAEEDFLLS...........QATLLEQVSSLQPLLDSNY.I.RDVPEHA.TKLQRLSQIHIKQQDQTEAQSLEVKKLFEEYNKMMFLLSKQFTQWDESL.................................
C1BL28_OSMMO/1-174               ..................................................MDKTIEIDNLEMRLQAMENRI.......Y.G...E.RR..T.RG....G....K...P..V...K...C.AE.SLT.......RIQAAL...GNT..ANKRERVK...I...LHKK..IEDL.LK.YLDPQ...F.TDHI.TVPDAM.KLEFILAEEDFLVS...........QAALLEQVSNLQPLLDSNY.I.RDVPEHA.TKLQRLSQIHIKEQDQTEAQSLEVRKLFEEYNKMMFLLSKQFTQWDESL.................................
H9KN22_APIME/1-173               .................................................m----AAIELLEDRVIELEKKI.......Y.G...L.AK..K.KE....N....NdtlE..N...P...V.ID.NIL.......HVNTLV...SSA..MSGREKAN...L...MIKR..LPEL.NT.YLDP-...I.IESS.EIPIEA.KLQLLLAMASEIKQ...........NHEMLKQVQELTPVLETDR.L.RNVPELT.NKLNDLNLSYLKLYEDTQGLNNHINEVFSKYNDVITSISKSLITIDA--iv...............................
H0WY21_OTOGA/1-172               .................................................m-AALTDVQRLQARVEELERWV.......Y.G...-.-P..G.GT....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ANKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVDALVPMLDSAH.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTLLLSKQFVQWDELL.................................
D3PH51_9MAXI/1-174               ...............................................mat-------EVLRKRITTLEKAV.......L.G...T.EG..DiLS....S....D...P..S..pP...I.VP.YLT.......EFAQSL...GNA..VEKRERIR...S...ILRD..VSSI.DT.FLDPN...F.GEER.GIPLSA.KGDIILAQKDVILK...........TNSLLERVDKSKGVLDQSQeLeKAVRHFE.PKFQKLAKIQVDQVKKEEELSHESLELIQKYNEIIEIVSKSFIDYDNL-l................................
I1GCY8_AMPQE/9-182               .............................................iaeey------ISSLQRRLDLLEERL.......I.G...Q.EK..V.RE....G....Q...P..Q...L...V.-H.LLK.......TIDGKL...KALvqSMKGNCVQ...Q...VWDT..IPDL.ER.ILDPA...Y.LRSL.NLNAPA.KKELLLYYVEQLQK...........YQNDIDDLQLLKETVNTTS.Y.QGTEAVE.KDLSQLAATHVQQEDEVVSLTSRVHLFIDQYTKLILQLSAQCVEWDEVV.................................
G1SD49_RABIT/1-172               .................................................m-AALTDVQRLQARVEELERWV.......Y.G...P.GG..V.RG....-....-...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILA...........QVALLEQVDALVPMLDSAH.I.KAVPEHA.ARLQRLAQIHIQQQDQCMEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
DCTN3_HUMAN/1-172                ..................................................MAGLTDLQRLQARVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..SSKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVNALVPMLDSAH.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
F4QEE8_DICFS/101-252             .......................................tlqsgsciseq---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.-LD.......RYRSQI...NNI..KTDNDTIN...SflnLYKD..NETL.FNtVMDND...A.IGNG.GLITSVeKLAIILSSEDDIKQ...........TARYLQLLSELEKFINSNS.V.SSIPSSI.TALKPLQSFHNEQQAITVALNKKLEQKIQSYNDIVEALSTRFAYWDMIL.................................
H9F5T1_MACMU/1-139               ..................................................---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVNALVPMLDSAH.I.KAVPEHA.ARLQHLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
Q5T1I6_HUMAN/1-117               ..................................................MAGLTDLQRLQARVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..SSKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAGNAGLHV...........-------------------.-.-------.-------------------------------------------------ymhlrmwvvgevkhrdglsiq............
H9GTI7_ANOCA/1-36                .................................................q---------------------.......-.-...-.--..-.--....-....-...-..-...-...I.GD.GLG.......KVQVAL...NNV..ASKRERVK...I...LFKK..SK--.--.-----...-.----.------.--------------...........-------------------.-.-------.-------------------------------------------------lsfkf............................
Q8NB28_HUMAN/1-117               ..................................................MAGLTDLQRLQARVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..SSKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAGNAGLHV...........-------------------.-.-------.-------------------------------------------------ymhlrmwvvgevkhrdglsiq............
G3NAA4_GASAC/2-175               ..................................................MDKTSDADNLEVRLQALESQI.......Y.G...E.RR..N.KS....G....K...P..V...K...C.AE.SLA.......RIQAGL...TNT..ANKRERVK...I...LHKK..IEDL.LK.YLDPQ...F.TDHI.TVPDAM.KLEFILAEEDFLLS...........QAALLEQVSNMQPLLDSTY.I.RDVPEHA.TKLQRLSQIHIKEQDQTEAQALEVKKLFEEYNKMMFLLSKQFTQWDETL.................................
G5BUY4_HETGA/38-74               .................................................v---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.---.......------...---..--------...-...----..----.--.-----...-.----.------.--------------...........-------------------.-.-------.-------------KDQCMEITEESKALLEEYNKTTMLLSKQFMQWDELL.................................
G3WYV2_SARHA/1-172               .................................................m-AALTEVQRLQARVEELERWV.......Y.G...-.-A..G.GA....R....S...S..R...K...V.AD.GLV.......KVQVAL...GNI..SSKRERVK...V...LFKK..IEDL.IK.YLDPE...Y.IDRI.TVPNAA.KLQFILAEEQFILS...........QVALLEQVEALAPLLDSSH.I.KAVPKHA.ARLQALSQIHIQQQDQCEEVTETTKALLEEYNKMTILLSKQFVQWDELL.................................
B9EQ42_SALSA/1-174               ..................................................MDRKVEVDNLETRLETLESRI.......Y.G...E.RR..N.KG....G....K...P..V...K...C.AD.SLS.......RVQAAL...ANT..ANKRERVK...I...LHKK..IEDL.LK.YLDPQ...F.TDHI.TVPDAM.KLEFILAEEDFLLC...........QATLLEQVSNLQPLLDSNY.I.RDVPEHA.TKLQRLSQIHIKEQDQTEAQSLEVKKLFEEYNKMMFLLSKQFTQWDESL.................................
A0AQB7_DROME/1-160               .................................................m----EALDILEKRIDALTRVL.......G.P...V.QD..S.EV....-....-...G..E...G...V.VD.ALC.......SAHAIL...GEA..TTGSAALQ...Q...CVKR..SDEL.EK.YLDPN...F.LEEH.QQVRS-.KEVYLQAVAPELHT...........QAEQLERIKQLEPALGAEY.F.RSIPAGClEQLKGITQNNGEYAQQSELIEE---------------------------slvlamkrygeiqaglls...............
B4MNL6_DROWI/1-162               ................................................md-----ALDILEKRIDALTRVL.......-.GplpD.GD..S.GS....D....K...T..A...N...V.VD.SLC.......SANSML...TEA..TTGRTELQ...K...CVAR..SGEL.EK.YLDPN...F.LEEQ.QQVRS-.KEVYLNAVAPDLHL...........QAEQLERIKKLEPALGAEY.F.RSIPSEC.--LDQLKQITANNGE----------------------------------yaqqselieeslilamkrygeiqagl.......
B3MF26_DROAN/1-161               ................................................me-----ALDILEKRIDALTRVL.......G.P...V.PD..S.DA....-....-...G..E...G...V.VD.ALC.......SAHALL...GEA..TTGSVPLQ...N...CVKR..APEL.EK.YLDPN...F.LEEQ.QQVRS-.KEVYLHAVAPELHT...........QAEQLDRIKQLEPALGAEY.F.RSIPSEClDQLKQITQNNGEYAQQSELIEE---------------------------slvlamkrygeiqagllss..............
B5G3H2_TAEGU/1-171               ..............................................maag---AAELRRLQWRLEELEQRV.......-.-...-.-G..L.GG....C....G...P..Q...K...V.AD.ELV.......KVQVAL...NNI..AGKRERIK...I...LFKK..IEDI.IK.YLDPQ...Y.IDRM.AVPDTM.KLQFILAEEQAIPA...........RAALLEQVKNLKPILDSTS.I.QAVPDHA.AKLQRLSQIHIQQQEKRHDLTDSVKTLLEDYNKMTLLLSKQFVQWNEIL.................................
E2RBC1_CANFA/1-172               ..................................................MAAVTDVQRLQARVEELERWV.......Y.G...-.-S..G.GP....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QIALLEQVEALVPMLDSAH.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEVTEESKALLEEYNKTTMLLSKQFVQWDELL.................................
E5SM01_TRISP/139-283             .......................ycrnyfsrmsqletlirtqsevsenfe---------------------.......-.-...-.--..-.--....-....-...-..E...S...I.LS.QYK.......TTKLAL...NEF..LQNKSKVI...E...YLQE..CKEA.CD.IIQPR...F.FIEI.LLSPNA.KLQLIMLKMDSLKA...........LIAMFAKVSSFSPVLNSES.I.RVVNSYP.SELTRTSE-----------------------------------------nfltaiaekeciqrkam................
E4YH01_OIKDI/1-156               ................................msiaelnrkldsleeqit---------------------.......-.-...-.--..-.--....-....-...-..E...K...N.II.SLA.......TAQTKL...DKI..-KKYANVD...T...LFKE..ISRL.SH.LLDLS...C.AEM-.-TPEAM.D-QLAISIEPIVKQ...........ISPYMDKVQSLEKYSHIGK.L.ENMIEKK.KDIQKLARLNSLQYERVQNLGENTGILLAHYNAIIDNLSRDFAVL----eaql.............................
G4VHB1_SCHMA/1-128               .................................................m---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.---.......------...-SV..AEKRSVSS...K...LLSR..INEI.QK.YTDPN...F.MEDD.TLLAQS.KIEIILAQRDRIEK...........IGSDLEKISKLRDCLNHPA.F.GEISTLK.QKFEDLRMVHNDQYVMSEKLIADTQALLDTYHNLIRDTSKLFIYWNQ--ra...............................
B4LK37_DROVI/1-170               .........................mealdilekridslnrvlgplpesy---------------------.......A.G...DaDG..S.ST....A....K...T..A...N...I.VD.TLC.......SANALL...GEA..TAGRTQLQ...Q...CVGR..AAEL.EK.YLDPN...F.LEDH.QQV-RT.KEVYINAVAPELYA...........QSEQLERIKQLEPALGAEY.F.RSIPSEClDKLKQITDNNGEYAQQSE-------------------------------lieeslilamkrygeiqaglls...........
E2C7L9_HARSA/1-174               .................................................m----SSIKLLEDRIANLEKQA.......Y.G...P.NK..AvNI....D....D...P..AplnA...V.ID.RLL.......DVNSLI...SSA..LSGREKPN...A...VIKR..LPEL.NG.YLDPV...S.-EDI.EMPTSA.KTQLLLTMESEIME...........NHKLLTKMQELMPVLESER.I.KDVPEFN.NTFNKLSLSYLKAYEDSEELSAHVHDLLSKYNAVISSISESLI------sldvai...........................
F2U056_SALS5/1-97                ..................................................---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.---.......------...---..--------...-...----..----.--.-----...-.---M.ATPDPV.KAQVILADQDRLQD...........TCRQFEAVSRGEKFINSEP.L.REVPSHS.VKLKPLRAVHLSQVEGARDQRDRVFSLLQAYNNVVMMLSEQFVKWDRIL.................................
B5G3H3_TAEGU/1-171               ..............................................maag---AAELRRLQWRLEELEQRV.......-.-...-.-G..L.GG....C....G...P..Q...K...V.AD.ELV.......KVQVAL...NNI..AGKRERIK...I...LFKK..IEDI.IK.YLDPQ...Y.IDRM.AVPDTM.KLQFILAEEQAIPA...........RAALLEQVKNLQPILDSTS.I.QAVPDHA.AKLQRLSQIHIQQQEKRHDLTDSVKTLLEDYNKMTLLLSKQFVQWNEIL.................................
A0AQB0_DROME/1-161               .................................................m----EALDILEKRIDALTRVL.......G.P...V.QD..S.EV....-....-...G..E...G...V.VD.ALC.......SAHAIL...GEA..TTGSAALQ...Q...CVKR..SDEL.EK.YLDPN...F.LEEH.QQVRS-.KEVYLQAVAPELHT...........QAEQLERIKQLEPALGAEY.F.RSIPAEClEQLKGITQNNGEYAQQSELIEES--------------------------lvlamkrygeiqagllss...............
G3USF6_MELGA/1-171               ................................................ma-AEMAALQQLHWRLEELEQRV.......-.-...-.-G..V.GA....C....E...P..S...K...V.AD.ELV.......RVQLAL...SNI..AGKRERIK...I...LFKK..IEDV.IK.YLDPQ...Y.IDRM.AVPDTM.KLQFILAEEQALPS...........RVALLEQVKNLEPVLDSAS.I.QAAPEHA.TKLQRLSQIQIQQQAPRHHGAGDKETIXLKRNIQTLLLSKQFVQWNEIL.................................
Q5ZK19_CHICK/1-171               ...............................................mag--EMAALQQLHWRLEELEQRM.......-.-...-.-G..V.GT....G....E...P..P...K...V.AD.ELV.......KVQVAL...SNI..AGKRERIK...I...LFKK..IEDV.IK.YLDPQ...Y.IDRM.AVPDTM.KLQFILAEEQALPS...........RVALLEQVKNLEPVLDSAS.I.QAAPEHA.AKLQRLSQIQIQQQEQCEQFTDEVKMLLENYNKTTLLLSKQFVQWNEIL.................................
H0UWG1_CAVPO/1-172               .................................................m-AALTDVQRLQARVEELERWV.......Y.G...-.-P..V.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDV.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVDTLLPMLDSAS.I.QAVPEHA.ARLQHLAQIHIQQQDQCVEITDESKTLLEEYNKTTMLLSKQFVQWDELL.................................
G1PY14_MYOLU/1-137               ...............................................maa---VPEVQRLQARVEELERWV.......Y.G...P.GG..S.R-....-....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..SSKRERVK...I...LFKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QIALLEQVEALVPMLDSAH.I.KAVPEHA.ACLQRLAQIHIQQQ-----------------------------------.................................
Q6GQL6_DANRE/1-174               ..................................................MEEKSNLEDLDARLQLLEKRV.......Y.G...E.RG..G.KN....G....K...P..V...K...C.AE.SLT.......RISAAL...ANT..ANKRERVK...I...LHKK..IEDL.LK.YLDPQ...F.TDFI.AVPDSV.KLEFILAEEEFLRS...........QAALLEQVQNMQPLLDSNH.I.KAVPELT.TKVQRLSQIHIQQQDQNEDLSAEVKRLFEEYNKMMFLLSKQFSQWDETL.................................
F7E9Z7_MONDO/1-83                .................................................q--------RLQARLEELERWV.......Y.G...-.-T..G.EA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..SSKRERVK...V...LYKK..IEDL.IK.YLDPE...Y.IDRI.TVPNAA.KLQFILA-------...........-------------------.-.-------.-------------------------------------------------a................................
G1Q0J6_MYOLU/1-95                ...............................................maa---VPEVQRLQARVEELERWV.......Y.G...P.GG..S.R-....-....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..SSKRERVK...I...LFKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAG------...........-------------------.-.-------.-------------------------------------------------mhvhl............................
Q54ZI7_DICDI/104-227             .......................senesinnfmliyksnetlfnkivdne---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.---.......------...---..--------...-...----..----.--.-----...-.----.SLLNSVeKLAIILSAEDEIYS...........TARNLQKLGELEKFINSSS.T.QSIPKLN.EALKPLENIHFEQEVIAIQLNKKLEEKVQSYNDIIQEISNRFAYWDSI-i................................
F6WBC9_CALJA/1-172               .................................................m-AALTDVQRLQARVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.SLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDM.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVSLLEQVNALVPMLDSAH.I.KAVPEHA.ARLQHLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
H2ZSA3_LATCH/1-173               .................................................m-AAGAELLRLEERIAELESRL.......Y.G...D.TG..G.R-....G....G...S..K...K...L.AD.GLI.......KVQASL...GNI..ASKRERIK...I...LYKK..IDDL.MK.YLDPQ...Y.IDRV.AVPDAM.KLEFILAEEQFLHS...........QAALLEQMNTLQPLMDSAH.I.KAVPDHA.SKLQALAQTHIQQQDQGQVITEDVRKLLEDYNKMTLLLSKQFLQWDEML.................................
E3XCQ6_ANODA/1-163               ................................................md-----ALSVIEKRLEHLNQLL.......-.G...P.LP..T.DE....G....Q...S..E...N...L.TE.AILsaasflpSASTGH...LSD..GAARSAIL...E...SFKR..KDEL.EA.YLDPA...F.IEEK.QDIK-A.KEMYINTIANDLAG...........TFETLQKIKTLEPTLGAEY.F.RNLPDVS.DQLKAMNTTMAEQKQANELLEE---------------------------slviamqrygeiqa...................
Q5DD70_SCHJA/1-176               ...............................................mla----MNIETLENRLCELERLV.......F.G...C.NK..P.VR....K....S...T..F...E...C.EK.NLV.......DQLYELysaMSV..AEKRSVSS...K...LLSR..INEI.QK.YIDPN...F.MEDD.ILLTKS.KIEIILAQKDRIQN...........IGNDLENISKLRDCLNHPA.F.GEISTLK.KKFEDLRMVHNDQYAVSEKLIADTQALLNTYHNLIRDTSKLFIYWN---lrv..............................
Q0C775_AEDAE/2-162               ..esldvisqridnlnqllgplpttdahgenltdavlsatsflpsastgh---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.---.......------...LAD..GSARDSIL...Q...TFQR..KEEL.EA.YLDPA...Y.LDEK.QDI-KA.KETYINTIANDLAG...........TFETLQKIKALEPTLGAEY.F.RNLPDVS.DQLKTMTIGTVEQKQ-ANDLLEE--------------------------slviamqryseiq....................
B4KM29_DROMO/1-162               ................................................me-----ALDILEKRIDALNRVLgplpeaqV.G...D.-D..G.NT....T....K...T..A...N...I.VD.TLC.......SANALL...SEA..TTGRIQVQ...Q...CVGR..AAEL.EK.YLDPN...Y.LEEQ.QQVRA-.KEVYINAVAPELYA...........QSEQLARIKQLEPALGAEY.F.RSIPSEC.--LDKLKQITENNDE----------------------------------yaqqselieeslilamkrygei...........
B0X536_CULQU/3-170               sldviskridnlyqlvgsapagdasgqvenltdsvlsaasflpsastghl---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.---.......------...-AD..GSARGSIL...E...VFER..KDEL.ET.YLDPS...Y.LDEK.QDIKA-.KEIYINTIANDLAG...........TFETLQKIKTLEPTLGAEY.F.RNLPDVS.DQLSTMTTATAEQTRANEELEKSMVALMQRYNEIQ--------------tglkds...........................
G1QY83_NOMLE/1-172               ..................................................MAGLTDLQRLQARVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..SSKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVNALVPMLDSAH.I.KAVPEHA.VHLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
H3JEL1_STRPU/2-147               .............................................sesek---------------------.......-.-...-.--..-.--....-....-...-..-...E...V.ID.NLH.......GVKQKI...AGL..TSGKSKTQ...A...LWKR..LEEL.NN.YLDPE...L.SSQL.TLSNDA.KTDIILAEEEQLKA...........QAVLLEKVKELSSVLDSEH.I.KGVSGLS.DRLVPLTTVQVKHEEEAKELGDETKKLLESYNNIITLISKQFVQWDEVM.................................
G1M7R7_AILME/2-173               ..................................................MAAVTDVQRLQARVEELERWV.......Y.G...-.-S..G.GP....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QIALLEQVEALVPMLDSAH.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
B4I8F7_DROSE/1-161               .................................................m----EALDILEKRIDALTRVL.......C.P...G.QD..S.EV....G....E...-..-...G...M.VD.ALC.......SAHVLL...GEA..TTGSAALQ...Q...CVKR..SDEL.EK.YLDPN...F.LEEH.HQVRS-.KEVYLHAVAPELHT...........QAEQLERIKQLEPALGAEY.F.RSIPAEClEQLKGITQNNGEYAQQSELIEES--------------------------lvlamkrygeiqagllss...............
H2PUL4_PONAB/1-172               ..................................................MAGLSDLQRLQARMEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..SSKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVNALVPMLDSAH.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
DCTN3_MOUSE/1-172                .................................................m-AALTDVQRLQSRVEELERWV.......Y.G...-.-P..G.GT....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPEAS.KLQFILAEEQFILS...........QVALLEQVNALVPVLDSAS.I.KAVPEHA.ARLQRLAQIHIQQQDQCVAITEESKALLEGYNKTTMLLSKQFVQWDELL.................................
G3HN24_CRIGR/279-379             ..............................nlagsgissinmaleingvv---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.---.......------...---..--------...-...--YT..VEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QAALLQQVDALVPMLDSAS.I.KAVPEHA.ARLQRLAQIHIQQQT----------------------------------m................................
B9EMM5_SALSA/1-174               ..................................................MDRKFEVDNLETRLETLESRI.......Y.G...E.RR..N.KG....G....K...P..V...K...C.AD.SLS.......RVQSAL...ANT..ANKRERVK...I...LHKK..IEDL.LK.YLDPQ...F.TDHI.TVPDAM.KLEFILAEEDFLLS...........QATLLEQVSNLQPLLDSNY.I.RDVPEHA.TKLQRLSQIHIKEQDQTEAQSLEVKKLFEEYNKMMFLLSKQFTQWDESL.................................
E9I852_SOLIN/11-187              ...............................................ale---MSSVKLLEDRIADLEKQV.......Y.G...L.GN..M.MS...iD....D...PtpS..nP...I.VD.QLI.......DINSLI...SSA..LSGREKPN...A...VIKR..LPEL.NS.YLEPT...S.ED-V.DMPASA.KAQLLLTMESEIME...........NHKLLAKVQELAPVLESER.I.RNAPELN.NKLNKISLTYLEAYEDSKELSTDVHELLSKYNAVINSISESLIILDN--av...............................
Q86E07_SCHJA/1-128               .................................................m---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.---.......------...-SV..AEKRSVSS...K...LLSR..INEI.QK.YIDPN...F.MEDD.ILLTKS.KIEIILAQKDRIQN...........IGNDLENISKLRDCLNHPA.F.GEISTLK.KKFEDLRMVHNDQYAVSEKLIADTQALLNTYHNLIRDTSKLFIYWN---lrv..............................
E9QB54_DANRE/1-167               ..................................................MEEKSNLEDLDARLQLLEKRV.......Y.G...E.RG..G.KN....G....K...P..V...K...C.AE.SLT.......RISAAL...ANT..ANKRERVK...I...LHKK..IEDL.LK.YLDPQ...F.TDFI.AVPDSV.KLEFILAEEEFLRS...........QAALLEQVQNMQPLLDSNH.I.KAVPELT.TKVQRLSQIHIQQQDQNEDLSAEVKRLFEEYNKM-------FSQWDETL.................................
F7G8T6_MONDO/1-172               .................................................m-AALTDVQRLQARLEELERWV.......Y.G...-.-T..G.EA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..SSKRERVK...V...LYKK..IEDL.IK.YLDPE...Y.IDRI.TVPNAA.KLQFILAEEQFILS...........QVALLEQVEALAPLLDSSH.I.KAVPKHA.TRLQALSQIHIQQQDQCEEVTEATKALLEEYNKMTILLSKQFVQWDELL.................................
E0VZI7_PEDHC/1-175               ..............................................matd---SEALDILEKKIHDLEVQV.......F.G...E.KV..E.AT....E....N...F..N...P...I.ID.SLL.......QANIMM...LAA..VSGREKFN...S...LFKR..LNEL.NN.YLDLN...P.LTED.PNGLNT.KLNIILSMKDELES...........TCEKMEKIDKLKTILDDDK.I.KNALLLK.DDLNNLLINHLSKKEKLNEISNDVNELSVQFNEVCLEISKSFFLLNEAI.................................
Q6NTU2_XENLA/1-168               .................................................m----AELREMLNRVQEVERRL.......Y.G...R.NG..V.E-....-....-...A..R...K...V.TD.GLL.......KAQMTL...GNI..AGKRERVK...T...LYKK..IEDL.MK.YLEPQ...Y.IDRI.ALPDAM.KLEFILAEEQYIMT...........QAELLEQLHSLTSYLDSDH.I.TAVPGQA.SRLQTLSQIHIKQQDQSEEITSETKRLLEDYNKMTVLLSKQFVLWDETL.................................
G3UU08_MELGA/1-171               ................................................ma-AEMAALQQLHWRLEELEQRV.......-.-...-.-G..V.GA....C....E...P..S...K...V.AD.ELV.......RVQLAL...SNI..AGKRERIK...I...LFKK..IEDV.IK.YLDPQ...Y.IDRM.AVPDTM.KLQFILAEEQALPS...........RVALLEQVKNLEPVLDSAS.I.QAAPEHA.TKLQRLSQIQIQQQVELSLHDDTVSMLAKQRNIQTLLLSKQFVQWNEIL.................................
F7HC42_MACMU/1-90                ..................................................MAGLTDVQRLQARVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILA-------...........-------------------.-.-------.-------------------------------------------------a................................
D2I3E6_AILME/1-172               ..................................................MAAVTDVQRLQARVEELERWV.......Y.G...-.-S..G.GP....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QIALLEQVEALVPMLDSAH.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
Q8I1F8_DROER/1-159               .................................................m----EALDILEKRIDALTRVL.......-.G...-.PG..Q.DS....E....V...G..E...G...V.VD.ALC.......SAHALL...GEA..TTGSAALQ...Q...CVKR..SDEL.EK.YLDPN...Y.LEEH.QQVRS-.KEVYLHAVAPELHT...........QAEQLERIKQLEPALGAEY.F.RSIPAEClEQLKGITQNNGEYAQQSELIEE---------------------------slvlamkrygeiqagll................
E9H327_DAPPU/1-171               ................................................ms----SELDAVEERLKRLEKYV.......L.G...E.DV..N.RQ....-....D...D..E...Q...L.ID.TML.......AVSRKL...ASV..VSKNEKVS...S...ALKR..ADEV.KK.YADPL...Y.AESEgFMPEAV.KLQLLLSKEEDMKE...........ALNHFQKMNLLKPVLDSQA.I.QNVPQLE.SQLYKISLQQESQEKKVSNLSDDTYALIKNYSNFVNDVSKKLVE-----veks.............................
G3NAA1_GASAC/1-174               ..................................................MDKTSDADNLEVRLQALESQI.......Y.G...E.RR..N.KS....G....K...P..V...K...C.AE.SLA.......RIQAGL...TNT..ANKRERVK...I...LHKK..IEDL.LK.YLDPQ...F.TDHI.TVPDAM.KLEFILAEEDFLLS...........QAALLEQVSNMQPLLDSTY.I.RDVPEHA.TKLQRLSQIHIKEQDQTEAQALEVKKLFEEYNKMMFLLSKQFTQWDETL.................................
F8W786_HUMAN/1-117               ..................................................MAGLTDLQRLQARVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..SSKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAGNAGLHV...........-------------------.-.-------.-------------------------------------------------ymhlrmwvvgevkhrdglsiq............
F7HA44_MACMU/1-100               ..................................................MAGLTDVQRLQARVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAERSSLSS...........-------------------.-.-------.-------------------------------------------------prlh.............................
F1A3B2_DICPU/60-219              ...................................rsrsssvsqqlhqqn---------------------.......-.-...-.--..-.--....Q....Q...Q..E...P...I.TE.SLE.......KFKAII...NKI..KSENESINnfmL...IYKA..NESL.FN.----K...V.MDNE.TLLNSVeKLAIILSAEDEIYT...........TSRNLQKLHELEKFINSNS.M.QSIPTLN.EKLKPIENVHFEQEIIAVQLNKKLEEKVQGYNDIIQEISNRFAYWDQIL.................................
C1BNV1_9MAXI/1-173               ...............................................mst-------EVLSKRIQSLERVV.......L.G...S.DE..S.SK....G....S...I..H...P...P.AVpFLN.......DFARDL...GNA..VDKRDRVR...G...VLRD..VSSL.NT.YLDPS...F.GEEK.GLPLNA.KADILLSQSESIHK...........TNDLLERLHKSKGVLDRSQeLeRAVKEFE.PKFNKLAQLQVDQENEAQEISKESLELMQKYNEIIEIVSKSFIQYDNIL.................................
DCTN3_BOVIN/1-172                ..................................................MAAVTDVQRLQARVEELERWV.......Y.G...P.GG..S.R-....-....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...V...LYKK..IEDL.IK.YLDPE...Y.IDRI.ALPDAS.KLQFILAEEQFILS...........QVALLEQVEALVPMLDSTH.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
B7Q631_IXOSC/9-182               .............................................maapd-----VLKILEERLEVLEMRL.......A.G...N.DW..G.KE....-....L...P..N...Ks.tI.TE.LLA.......NVNSKI...QAA..VASREKLS...V...L-KK..TEEL.DR.YLDAE...Y.QEKI.DLTEGA.KLQLILAEEDRLRQ...........VIAAYQKMEDLKPVLDSEH.I.KDAPSLF.GKVSALAAIQLEQQEEVDEQTQKLYHLLSTYNDLVNTISKQFLLWDNML.................................
H2ZSA2_LATCH/1-164               .................................................m-AAGAELLRLEERIAELESRL.......Y.G...D.TG..G.R-....G....G...S..K...K...L.AD.GLI.......KVQASL...GNI..ASKRERIK...I...LYKK..IDDL.MK.YLDPQ...Y.IDRV.AVPDAM.KLEFILAEEQFLHS...........QAALLEQMNTLQPLMDSAH.I.KAVPDHA.SKLQALAQTHIQQQDQGQVITEDVRKLLEDYNKMV--------------sfkcc............................
C3XR47_BRAFL/1-172               ..................................................MADGSEISVLEARLQRLEEAV.......Y.G...E.EG..E.QR....S....E...P..A...-...-.VE.SLA.......NFQGHV...NSS..LEGYDRIK...Q...AWRK..LEDI.EK.YLDPA...F.VDRL.TLPDTA.KAEIVLSAEKDMKA...........LAAQLEEVQKMKDVFDSEH.I.RATANYT.SQLHSLAQVHLEQQEQAEVLTDDVRRLLSEYNRLVDLMSKQFVLWDETL.................................
Q292H9_DROPS/1-155               ................................................md-----ALDILEKRIDALTRVL.......-.G...P.VR..E.TE....-....S...D..E...G...I.VD.SLC.......SANALL...SEA..TTGRAQLQ...Q...CVGR..AAEL.EK.YLDPN...F.LDEH.QQVRS-.KEVYLNAVAPEMHT...........QAEQLERIKQLEPALGAEY.F.RSIPSEClDQLKQVTQNNGEYAQQSELIE----------------------------eslilamkrygeiq...................
G3TJS5_LOXAF/1-172               ..................................................MAAVTDLQRLQTGVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVEALVPMLDSPH.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEVTEESRALLEEYNKTTMLLSKQFVQWDELL.................................
B4GDG4_DROPE/1-158               ................................................md-----ALDILEKRIDALTRVL.......-.G...P.VR..E.AE....-....S...D..E...G...I.VD.SLC.......SANALL...SEA..TTGRAQLQ...Q...CVGR..AAEL.EK.YLDPN...F.LDEH.QQVRS-.KEVYLNAVAPELHT...........QAEQLERIKQLEPALGAEY.F.RSIPSEClDQLKQVTQNNGEYAQQSELIE----------------------------eslilamkrygeiqegl................
H2QX67_PANTR/1-172               ..................................................MAGLTDLQRLQARVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..SSKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVNALVPMLDSAH.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
F7HC42_MACMU/88-144              .................................................l---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.---.......------...---..--------...-...----..----.--.-----...-.----.------.--------------...........-------------------.-.AAVPEHA.ARLQHLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
Q9W1V8_DROME/1-161               .................................................m----EALDILEKRIDALTRVL.......G.P...V.QD..S.EV....-....-...G..E...G...V.VD.ALC.......SAHAIL...GEA..TTGSAALQ...Q...CVKR..SDEL.EK.YLDPN...F.LEEH.QQVRS-.KEVYLQAVAPELHT...........QAEQLERIKQLEPALGAEY.F.RSIPAEClEQLKGITQNNGEYAQQSELIEES--------------------------lvlamkrygeiqagllss...............
D4A1B8_RAT/1-172                 .................................................m-AALTDVQRLQSRVEELERWV.......Y.G...-.-P..G.GT....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPEAS.KLQFILAEEQFILS...........QVALLEQVNTLVPMLDSAS.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
G7NFL4_MACMU/1-172               ..................................................MAGLTDVQRLQARVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVNALVPMLDSAH.I.KAVPEHA.ARLQHLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
F6W1Z3_CIOIN/1-170               ..................................................MTEEALLASLEERVLELEKRV.......L.P...-.--..-.KD....G....K...D..E...S...L.LT.SLQ.......KVNFML...TSA..ATDRERFK...Q...VFNR..VPQI.VE.YLSPG...F.IQSI.SMDNTC.EKEAILASEQDIRK...........SHEDFTTIERLSKVLGSQE.I.QSVPKHE.KRLASLEHIQLNQMEEMNKVSEEFQDLLLMYNQLVTTLSENFVHWDWV-l................................
G7PS31_MACFA/1-172               ..................................................MAGLTDVQRLQARVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVNALVPMLDSAH.I.KAVPEHA.ARLQHLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
G4Z2G4_PHYSP/77-172              ..............................................srag---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.---.......------...---..--------...-...----..----.--.-----...-.----.---DEL.KRATILSSADQVQR...........VAAQLQQLQQLSSVLDQLR.A.PDA-GHS.TRLTQLEAAGELQSERALALHGRVEKLLATYQQMMLVLSEKCVEYNA--ll...............................
A4IIY6_XENTR/1-168               .................................................m----AELREMQGRLSEVERRL.......Y.G...-.-R..S.GT....-....E...P..S...K...V.AD.GLL.......KAQVAL...GNI..AGKRERVK...T...LYKK..IEDL.MK.YLEPQ...Y.IDRI.ALPDAM.KLEFILAEEQYILA...........QVSLLEQLHGLTPYLDSEH.I.KAVPGQA.SRLQTLSQIHIQQQDQSEEITGEAKRLLEDYNKMTVLLSKQFVLWDETI.................................
G6DKN2_DANPL/1-172               ............................................mdpiav---------LQSRIEQLEAKL.......-.G...I.NA..C.NIi.egQ....Q...G..D...S...A.TA.NLL.......NTAQAI...NNA..TAEHEKLK...E...ARNM..ANEL.NN.YTDPN...L.AENL.Q-QNNM.HMHEVVAAEPVIQH...........HCHCMHHCKQAAPVLESEP.I.QQVPVMQ.ETVNKMHLAAAEVKAEADSVSQGIQELAETC------------------gtaasktseqlaavaqkv...............
E9Q919_MOUSE/1-149               .................................................m-AALTDVQRLQSRVEELERWV.......Y.G...-.-P..G.GT....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPEAS.KLQFILAEEQFILS...........QVALLEQVNALVPVLDSAS.I.KAVPEHA.ARLQRLAQIHIQQQ-----------------------------------fvqwdellcqle.....................
G1NWU1_MYOLU/1-172               ..............................................maav----PVVQRLQARVEELERWV.......Y.G...P.GG..S.R-....-....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LFKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QIALLEQVEALVPMLDSAH.I.KAVPEHA.ACLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTLLLSKQFVQWDELL.................................
Q6NTT9_XENLA/1-168               .................................................m----SELREMLNRLQEVDRRL.......Y.G...-.-R..S.GA....-....E...P..R...K...V.AV.GLL.......KAQVAL...GNI..AAKRERVK...T...LYKK..IEDL.MK.YLEPQ...Y.IDRI.ALPDAM.KLEFILAEEQYIVA...........QAELLEQLHSLTSYLDSDH.I.TAVPGQA.SRLQTLSQIHIKQQDQSEEITGETKRLLEDYNKMTVLLSKQFVLWDETV.................................
H9J1G0_BOMMO/1-172               ............................................mdpiav---------LQSRIEQLEAKLg.....lS.P...E.IS..I.DG....Q....Q...G..D...S...V.TA.NLL.......SAAQAI...NNA..TAGHEKLH...E...AMQM..ASEL.NN.YSDPN...F.VENL.QKNDLH.KQE-VLAAEPVIRH...........HCRCMQQCKQATPVLESEA.I.QKAAQMQ.PTVDKMHAAAAEVKAEADAVSHGIQQLAET-------------------cgsaandssqqlanvaqmv..............
F1SEC0_PIG/1-172                 ..................................................MAGVTDVQRLQARLEELERWV.......Y.G...P.GG..S.R-....-....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.MDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVEALVPMLDSAH.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
F6ZVN7_HORSE/1-172               ..................................................MAAVTDVQRLQARVEELERWV.......Y.G...P.GG..S.R-....-....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IR.YLDPE...Y.IGRI.AMPDAS.KLQFVLAEEQFVLS...........QVALLEQVEALVPMLDSAH.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEVTEESKALLEEYNKTTMLLSKQFVQWDELL.................................
H2RKX5_TAKRU/2-175               ..................................................MDRQLEMDSLEMRLQVLENRI.......Y.G...E.KR..S.KS....A....K...P..I...K...C.AE.SLA.......KIQAGL...INT..GNKRERVK...I...LHKK..IEDL.LK.YLDPQ...F.TDHI.TLPDAM.KLEFILAEEAFLFS...........HAALLEQISNMQPLLDSSY.I.RDVPEHA.TKLQRLSQIHVRQQDQMEAQSQEVKKLFEEYNKMMFLLSKQFTQWDQS-l................................
B5G3H5_TAEGU/1-52                ..............................................maag---AAELRRLQWRLEELEQRV.......-.-...-.-G..L.GG....C....G...P..Q...K...V.AD.ELV.......KVQVAL...NNY..--------...-...----..----.--.-----...-.----.------.--------------...........-------------------.-.-------.-------------------------------------------------rrqege...........................
F7E9Z7_MONDO/82-137              .................................................a---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.---.......------...---..--------...-...----..----.--.-----...-.----.------.--------------...........-------------------.-.-AVPKHA.TRLQALSQIHIQQQDQCEEVTEATKALLEEYNKMTILLSKQFVQWDELL.................................
C1BI38_ONCMY/1-174               ..................................................MDRKVEVDNLETRLEMLESRI.......Y.G...E.RR..N.KG....G....K...P..M...K...C.AD.SLS.......RVQAAL...ANT..ANKRERVK...I...LHKK..IEDL.LK.YLDPQ...F.TDHI.TVPDAM.KLEFILAEEDFLLS...........QATLLEQVSNLQPLLDSNY.I.RDVPEHA.TKLQRLSQIHIKEQDQTEAQSLEVKKLFEEYNKMMFLLSKQFTQWDESL.................................
B9EP16_SALSA/1-174               ..................................................MDRKVEVDNLETRLETLESRI.......Y.G...E.RR..N.KG....G....K...P..V...K...C.AD.SLS.......RVQAAL...ANT..ANKRERVK...I...LHKK..IEDL.LK.YLDPQ...F.TDHI.TVPDAM.KLEFILAEEDFLLC...........QATLLEQVSNLQPLLDSNY.I.RDVPEHA.TKLQRLSQIHIKEQDQTEAQSLEVKKLFEEYNKMMFLLSKQFTQWDESL.................................
B5G3H6_TAEGU/1-56                ..............................................maag---AAELRRLQWRLEELEQRV.......-.-...-.-G..L.GG....C....G...P..Q...K...V.AD.ELV.......KVQVAL...NNI..AGKRERIK...-...----..----.--.-----...-.----.------.--------------...........-------------------.-.-------.-------------------------------------------------xp...............................
Q4QR40_XENLA/1-166               .................................................e------LREMLNRLQEVDRRL.......Y.G...-.-R..S.GA....-....E...P..R...K...V.AV.GLL.......KAQVAL...GNI..AGKRERVK...T...LYKK..IEDL.MK.YLEPQ...Y.IDRI.ALPDAM.KLEFILAEEQYIVA...........QAELLEQLHSLTSYLDSDH.I.TAVPGQA.SRLQTLSQIHIKQQDQSEEITGETKRLLEDYNKMTVLLSKQFVLWDETV.................................
B4P919_DROYA/1-160               .................................................m----EALDILEKRIDALTRVL.......-.G...-.PG..Q.DS....E....V...S..E...G...V.VD.ALC.......SAHALL...GEA..TTGSAALQ...Q...CVKR..SDEL.EK.YLDPN...F.LEEH.QQVRS-.KEVYLHAVAPELHT...........QAEQLERIKQLEPALGAEY.F.RSIPAEClEQLKGIT------------------------------------------enngeyaqqselieeslvlamkrygeiqaglls
A0AQB1_DROME/1-160               .................................................m----EALDILEKRIDALTRVL.......G.P...V.QD..S.EV....G....E...-..-...G...V.VG.ALC.......SAHAIL...GEA..TTGSAALQ...Q...CVKR..SDEL.EK.YLDPN...F.LEEH.QQVRS-.KEVYLQAVAPELHT...........QAEQLERIKQLEPALGAEY.F.RSIPAEClEQLKGITQNNGEYAQQSELIEES--------------------------lvlamkrygeiqaglls................
F7HC36_MACMU/1-162               ..................................................MAGLTDVQRLQARVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVNALVPMLDSAH.I.KAVPEHA.ARLQHLAQIHIQQQA----------------------------------pwgvgvpdkagslvedvgfarlls.........
F7BRF6_XENTR/1-57                ..................................................---------------------.......-.-...-.--..-.--....-....-...-..-...-...-.--.---.......------...---..--------...-...----..VEDL.MK.YLEPQ...Y.IDRI.ALPDAM.KLEFILAEEQYILA...........QVSLLEQLHGLTPYLDSEH.I.K------.-------------------------------------------------.................................
G3QK97_GORGO/1-172               ..................................................MAGLTDLQRLQARVEELERWV.......Y.G...-.-P..G.GA....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..SSKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QVALLEQVNALVPMLDSAH.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTLLLSKQFVQWDELL.................................
F8UU20_AILME/1-172               ..................................................MAAVTGVQRLQARVEELERWV.......Y.G...-.-S..G.GP....R....G...S..R...K...V.AD.GLV.......KVQVAL...GNI..ASKRERVK...I...LYKK..IEDL.IK.YLDPE...Y.IDRI.AIPDAS.KLQFILAEEQFILS...........QIALLEQVEALVPMLDSAH.I.KAVPEHA.ARLQRLAQIHIQQQDQCVEITEESKALLEEYNKTTMLLSKQFVQWDELL.................................
#=GC seq_cons                    .......................................................tlp.LptRlptLEphl.......h.G......t..s.ts....t....t...s..p...p...l.sD.uLs.......clpstL...ush..usKRE+l+...h...LaK+..l--L.hK.YLDPp...a.lDcl.slPcu..KLpaILApEp.lhs...........psthLEplppLpPhL-Stt.l.+slPpps.s+LppLuQlalpQp-ps.tlspcsptLhppYNphh..lScpFh.ast...................................
//
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