#=GF ID   EZH2_WD-Binding
#=GF AC   PF11616.7
#=GF DE   WD repeat binding protein EZH2
#=GF AU   Pollington J
#=GF SE   pdb_2qxv
#=GF GA   25.00 25.00;
#=GF TC   44.30 43.50;
#=GF NC   20.20 18.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   17937919
#=GF RT   Structural basis of EZH2 recognition by EED. 
#=GF RA   Han Z, Xing X, Hu M, Zhang Y, Liu P, Chai J; 
#=GF RL   Structure. 2007;15:1306-1315.
#=GF DR   INTERPRO; IPR021654;
#=GF CC   This family of proteins represents Enhancer of zest homolog 2,
#=GF CC   (EZH2) a 30 residue peptide which binds to a WD-repeat domain of
#=GF CC   EED by residues 39-68. EED is a component of PRC2 complex which
#=GF CC   is involved in gene expression [1]. This interaction is required
#=GF CC   for the HMTase activity of PCR2 [1].
#=GF SQ   226
#=GS A0A091PE45_LEPDC/27-56    AC A0A091PE45.1
#=GS F6ZEX1_MACMU/39-68        AC F6ZEX1.1
#=GS A0A096MIJ9_POEFO/45-74    AC A0A096MIJ9.1
#=GS A0A091KFD5_9GRUI/42-71    AC A0A091KFD5.1
#=GS F1QQ58_DANRE/39-68        AC F1QQ58.1
#=GS I3L7H6_PIG/39-68          AC I3L7H6.1
#=GS E1BD02_BOVIN/39-68        AC E1BD02.2
#=GS A0A093FZC6_PICPB/1-30     AC A0A093FZC6.1
#=GS H0X2K5_OTOGA/39-68        AC H0X2K5.1
#=GS A0A0F8B6T2_LARCR/119-148  AC A0A0F8B6T2.1
#=GS G3GXG1_CRIGR/39-68        AC G3GXG1.1
#=GS F1LZH3_RAT/39-68          AC F1LZH3.2
#=GS G5B4F8_HETGA/39-68        AC G5B4F8.1
#=GS H3C8R8_TETNG/44-73        AC H3C8R8.1
#=GS H2LHB3_ORYLA/25-54        AC H2LHB3.1
#=GS A0A093GTX8_TYTAL/42-71    AC A0A093GTX8.1
#=GS H3C8Y8_TETNG/39-68        AC H3C8Y8.1
#=GS EZH2_MOUSE/39-68          AC Q61188.2
#=GS EZH2_MOUSE/39-68          DR PDB; 2QXV B; 40-68;
#=GS F6ZGV1_XENTR/40-68        AC F6ZGV1.1
#=GS H2SFW8_TAKRU/39-68        AC H2SFW8.1
#=GS W5N725_LEPOC/39-68        AC W5N725.1
#=GS H2UN45_TAKRU/25-54        AC H2UN45.1
#=GS U3K6U9_FICAL/39-68        AC U3K6U9.1
#=GS L5K0U5_PTEAL/39-68        AC L5K0U5.1
#=GS A0A099ZXB0_CHAVO/27-56    AC A0A099ZXB0.1
#=GS F6YRI3_MONDO/40-69        AC F6YRI3.1
#=GS E2R6Q2_CANLF/39-68        AC E2R6Q2.1
#=GS K7EIH5_HUMAN/39-68        AC K7EIH5.1
#=GS A0A091FNP4_9AVES/27-56    AC A0A091FNP4.1
#=GS G1LJS4_AILME/39-68        AC G1LJS4.1
#=GS A0A087QHS2_APTFO/42-71    AC A0A087QHS2.1
#=GS H2UN46_TAKRU/25-54        AC H2UN46.1
#=GS A0A091P149_HALAL/42-71    AC A0A091P149.1
#=GS G1KPU3_ANOCA/44-73        AC G1KPU3.2
#=GS H3DQW4_TETNG/1-30         AC H3DQW4.1
#=GS A0A094KUX9_ANTCR/42-71    AC A0A094KUX9.1
#=GS G1RM60_NOMLE/10-33        AC G1RM60.2
#=GS EZH1_PONAB/39-68          AC Q5RDS6.1
#=GS G3P0V9_GASAC/45-74        AC G3P0V9.1
#=GS G3XAL2_HUMAN/39-68        AC G3XAL2.1
#=GS K7EPC0_HUMAN/39-68        AC K7EPC0.1
#=GS Q29RB7_DANRE/45-74        AC Q29RB7.1
#=GS A0A093PJ75_9PASS/42-71    AC A0A093PJ75.1
#=GS H2UN48_TAKRU/25-54        AC H2UN48.1
#=GS E1C0W5_CHICK/39-68        AC E1C0W5.2
#=GS H2UN49_TAKRU/49-78        AC H2UN49.1
#=GS H3AXZ3_LATCH/55-84        AC H3AXZ3.1
#=GS A0A0A0A1R6_CHAVO/42-71    AC A0A0A0A1R6.1
#=GS I3IY41_ORENI/25-54        AC I3IY41.1
#=GS G1MY19_MELGA/39-68        AC G1MY19.2
#=GS H3D2A7_TETNG/41-70        AC H3D2A7.1
#=GS EZH1_MOUSE/39-68          AC P70351.1
#=GS M4ACI0_XIPMA/39-68        AC M4ACI0.1
#=GS A0A151PBG5_ALLMI/44-73    AC A0A151PBG5.1
#=GS G1KPH4_ANOCA/42-71        AC G1KPH4.1
#=GS G1KPH4_ANOCA/42-71        DR PDB; 5IJ8 A; 39-68;
#=GS G1KPH4_ANOCA/42-71        DR PDB; 5IJ7 B; 39-68;
#=GS G1KPH4_ANOCA/42-71        DR PDB; 5IJ7 A; 39-68;
#=GS G1KPH4_ANOCA/42-71        DR PDB; 5IJ8 B; 39-68;
#=GS F6X2U8_ORNAN/52-81        AC F6X2U8.2
#=GS I3M721_ICTTR/39-68        AC I3M721.1
#=GS A0A091R240_MERNU/42-71    AC A0A091R240.1
#=GS A0A093LKV5_EURHL/41-70    AC A0A093LKV5.1
#=GS M3WIA3_FELCA/39-68        AC M3WIA3.1
#=GS A0A096P5U8_PAPAN/39-68    AC A0A096P5U8.1
#=GS A0A094M2E6_9AVES/42-71    AC A0A094M2E6.1
#=GS A0A151P243_ALLMI/96-125   AC A0A151P243.1
#=GS A0A087XF77_POEFO/39-68    AC A0A087XF77.2
#=GS A0A091IKZ5_9AVES/27-56    AC A0A091IKZ5.1
#=GS A0A091NS73_APAVI/42-71    AC A0A091NS73.1
#=GS A0A091HQU7_CALAN/25-54    AC A0A091HQU7.1
#=GS U3ISV6_ANAPL/72-101       AC U3ISV6.1
#=GS E9PDH6_HUMAN/39-68        AC E9PDH6.1
#=GS A0A091IK45_CALAN/42-71    AC A0A091IK45.1
#=GS A0A087QJA0_APTFO/27-56    AC A0A087QJA0.1
#=GS K7ESX8_PONAB/39-68        AC K7ESX8.1
#=GS H2QD33_PANTR/42-71        AC H2QD33.1
#=GS W5NZD9_SHEEP/42-71        AC W5NZD9.1
#=GS A0A0D9S1H8_CHLSB/39-68    AC A0A0D9S1H8.1
#=GS G1MRP0_MELGA/42-71        AC G1MRP0.2
#=GS H2PNY7_PONAB/39-68        AC H2PNY7.1
#=GS M7BXG7_CHEMY/100-129      AC M7BXG7.1
#=GS A0A096N0B2_PAPAN/39-68    AC A0A096N0B2.1
#=GS G7P1J2_MACFA/39-68        AC G7P1J2.1
#=GS W5KZK5_ASTMX/48-77        AC W5KZK5.1
#=GS A0A0R4IP69_DANRE/39-68    AC A0A0R4IP69.1
#=GS A0A0Q3M8J4_AMAAE/39-68    AC A0A0Q3M8J4.1
#=GS K7G9J0_PELSI/54-83        AC K7G9J0.1
#=GS L9JZV6_TUPCH/39-68        AC L9JZV6.1
#=GS H3C7G6_TETNG/1-30         AC H3C7G6.1
#=GS F6WSH0_HORSE/39-68        AC F6WSH0.1
#=GS H0X1I6_OTOGA/39-68        AC H0X1I6.1
#=GS A0A091H9K6_BUCRH/42-71    AC A0A091H9K6.1
#=GS A0A093G904_PICPB/42-71    AC A0A093G904.1
#=GS A0A091GH95_9AVES/41-70    AC A0A091GH95.1
#=GS A0A091M0L3_CARIC/42-71    AC A0A091M0L3.1
#=GS F7EPP0_CALJA/39-68        AC F7EPP0.1
#=GS B5DFE2_RAT/39-68          AC B5DFE2.1
#=GS F6VUP3_CALJA/39-68        AC F6VUP3.1
#=GS H0VLN2_CAVPO/39-68        AC H0VLN2.1
#=GS G5BDP3_HETGA/66-95        AC G5BDP3.1
#=GS I3KMB2_ORENI/39-68        AC I3KMB2.1
#=GS F1PG04_CANLF/42-71        AC F1PG04.2
#=GS L5JTD3_PTEAL/39-68        AC L5JTD3.1
#=GS E9PWK3_MOUSE/39-68        AC E9PWK3.1
#=GS G3NPN1_GASAC/39-68        AC G3NPN1.1
#=GS F7AIG6_MONDO/39-68        AC F7AIG6.1
#=GS H2UN47_TAKRU/25-54        AC H2UN47.1
#=GS H0YU73_TAEGU/42-71        AC H0YU73.1
#=GS F6QA88_CALJA/39-68        AC F6QA88.1
#=GS H2QVK6_PANTR/39-68        AC H2QVK6.1
#=GS A0A093FUR7_GAVST/27-56    AC A0A093FUR7.1
#=GS A0A093IAL0_FULGA/42-71    AC A0A093IAL0.1
#=GS F6Q6T3_CALJA/39-68        AC F6Q6T3.1
#=GS W5N3Q8_LEPOC/177-205      AC W5N3Q8.1
#=GS F1NBM3_CHICK/39-68        AC F1NBM3.2
#=GS H3CF02_TETNG/39-68        AC H3CF02.1
#=GS F7HE52_MACMU/79-108       AC F7HE52.1
#=GS A0A093FV98_TYTAL/41-70    AC A0A093FV98.1
#=GS A0A091E603_CORBR/25-54    AC A0A091E603.1
#=GS F6WCU8_CALJA/39-67        AC F6WCU8.1
#=GS H3AXZ4_LATCH/39-68        AC H3AXZ4.1
#=GS G3S979_GORGO/39-68        AC G3S979.1
#=GS G1NY06_MYOLU/42-71        AC G1NY06.1
#=GS A0A093TN98_PHACA/42-71    AC A0A093TN98.1
#=GS G1L7Y5_AILME/39-68        AC G1L7Y5.1
#=GS F7F310_CALJA/39-68        AC F7F310.1
#=GS A0A091VLE3_OPIHO/42-71    AC A0A091VLE3.1
#=GS A0A091KTP8_9GRUI/42-71    AC A0A091KTP8.1
#=GS A0A091MBM1_CARIC/42-71    AC A0A091MBM1.1
#=GS A0A091IN18_9AVES/42-71    AC A0A091IN18.1
#=GS J9P0Q3_CANLF/39-68        AC J9P0Q3.1
#=GS F7EPM9_CALJA/39-68        AC F7EPM9.1
#=GS A0A091XNZ1_OPIHO/42-71    AC A0A091XNZ1.1
#=GS G8F640_MACFA/1-29         AC G8F640.1
#=GS G3RFW0_GORGO/42-71        AC G3RFW0.1
#=GS H0ZUE4_TAEGU/41-70        AC H0ZUE4.1
#=GS EZH2_DANRE/39-68          AC Q08BS4.1
#=GS F7B7S5_MACMU/39-68        AC F7B7S5.1
#=GS A0A099YX73_TINGU/27-56    AC A0A099YX73.1
#=GS F7BXB4_MONDO/59-88        AC F7BXB4.2
#=GS A0A091D4Y5_FUKDA/39-68    AC A0A091D4Y5.1
#=GS R4GB81_ANOCA/39-68        AC R4GB81.1
#=GS A0A091GQH5_BUCRH/41-70    AC A0A091GQH5.1
#=GS U3JD86_FICAL/44-73        AC U3JD86.1
#=GS A0A151P238_ALLMI/96-125   AC A0A151P238.1
#=GS A0A091EQF7_CORBR/42-71    AC A0A091EQF7.1
#=GS S7MMW0_MYOBR/39-68        AC S7MMW0.1
#=GS H3CEU8_TETNG/39-68        AC H3CEU8.1
#=GS G1SQ77_RABIT/44-73        AC G1SQ77.2
#=GS L9LD52_TUPCH/75-103       AC L9LD52.1
#=GS A0A087Y758_POEFO/61-90    AC A0A087Y758.2
#=GS F6WSU9_HORSE/41-70        AC F6WSU9.1
#=GS F7ANW1_ORNAN/94-123       AC F7ANW1.2
#=GS G3WZR9_SARHA/39-68        AC G3WZR9.1
#=GS A0A091N1J7_9PASS/42-71    AC A0A091N1J7.1
#=GS A0A0Q3PUX6_AMAAE/92-121   AC A0A0Q3PUX6.1
#=GS A0A099Z7D8_TINGU/42-71    AC A0A099Z7D8.1
#=GS W5QC07_SHEEP/39-68        AC W5QC07.1
#=GS G1SFW6_RABIT/39-68        AC G1SFW6.2
#=GS H3ANA1_LATCH/42-71        AC H3ANA1.1
#=GS A0A0A0MSY9_HUMAN/39-68    AC A0A0A0MSY9.1
#=GS F1S1G9_PIG/39-68          AC F1S1G9.2
#=GS F8W619_DANRE/45-74        AC F8W619.1
#=GS G3HLY5_CRIGR/39-68        AC G3HLY5.1
#=GS A0A087VQ59_BALRE/42-71    AC A0A087VQ59.1
#=GS G3SNT7_LOXAF/39-68        AC G3SNT7.1
#=GS A0A091MQ77_9PASS/25-54    AC A0A091MQ77.1
#=GS F6YRR3_CALJA/42-71        AC F6YRR3.1
#=GS K7EM79_HUMAN/39-68        AC K7EM79.8
#=GS I3IY40_ORENI/57-86        AC I3IY40.1
#=GS W5LQ79_ASTMX/39-68        AC W5LQ79.1
#=GS A0A093PW62_9PASS/25-54    AC A0A093PW62.1
#=GS E7FFB7_DANRE/45-74        AC E7FFB7.2
#=GS A0A094KII5_ANTCR/42-71    AC A0A094KII5.1
#=GS F6SP16_MONDO/39-68        AC F6SP16.1
#=GS EZH2_HUMAN/39-68          AC Q15910.2
#=GS EZH2_HUMAN/39-68          DR PDB; 5HYN F; 39-68;
#=GS EZH2_HUMAN/39-68          DR PDB; 5HYN A; 39-68;
#=GS EZH2_HUMAN/39-68          DR PDB; 5HYN K; 39-68;
#=GS EZH2_HUMAN/39-68          DR PDB; 5HYN Q; 39-68;
#=GS A0A0P7YN30_9TELE/39-68    AC A0A0P7YN30.1
#=GS A0A0R4IDP8_DANRE/45-74    AC A0A0R4IDP8.1
#=GS S7N8Q1_MYOBR/43-72        AC S7N8Q1.1
#=GS A0A093F1L1_GAVST/42-71    AC A0A093F1L1.1
#=GS M7BVS3_CHEMY/39-68        AC M7BVS3.1
#=GS A0A091JS62_COLST/25-54    AC A0A091JS62.1
#=GS A0A093I325_STRCA/42-71    AC A0A093I325.1
#=GS A0A091DDG6_FUKDA/39-68    AC A0A091DDG6.1
#=GS A0A093IPV2_EURHL/42-71    AC A0A093IPV2.1
#=GS A0A091LD24_CATAU/42-71    AC A0A091LD24.1
#=GS D3Z774_MOUSE/39-68        AC D3Z774.1
#=GS G1P1J7_MYOLU/39-68        AC G1P1J7.1
#=GS A0A0P7Z1C9_9TELE/44-73    AC A0A0P7Z1C9.1
#=GS A0A091SXQ2_9AVES/42-71    AC A0A091SXQ2.1
#=GS V8NTZ9_OPHHA/61-90        AC V8NTZ9.1
#=GS K7GH72_PELSI/39-68        AC K7GH72.1
#=GS A0A0D9R3X6_CHLSB/39-68    AC A0A0D9R3X6.1
#=GS S9XJ27_CAMFR/49-78        AC S9XJ27.1
#=GS A0A087VB36_BALRE/42-71    AC A0A087VB36.1
#=GS Q6AXH7_MOUSE/39-68        AC Q6AXH7.1
#=GS K7ENP2_HUMAN/39-68        AC K7ENP2.1
#=GS A0A0P7UPN2_9TELE/46-75    AC A0A0P7UPN2.1
#=GS A0A091VA65_NIPNI/42-71    AC A0A091VA65.1
#=GS M3W9W8_FELCA/2-31         AC M3W9W8.1
#=GS G3WZR8_SARHA/41-70        AC G3WZR8.1
#=GS H2UN44_TAKRU/25-54        AC H2UN44.1
#=GS G5CA03_HETGA/124-153      AC G5CA03.1
#=GS F6ZEW3_MACMU/39-68        AC F6ZEW3.1
#=GS X1WHS1_DANRE/39-68        AC X1WHS1.1
#=GS EZH1_BOVIN/39-68          AC A7E2Z2.2
#=GS G1QTY8_NOMLE/39-68        AC G1QTY8.2
#=GS G3T5L6_LOXAF/39-68        AC G3T5L6.1
#=GS G3PG18_GASAC/39-68        AC G3PG18.1
#=GS H0V1I5_CAVPO/42-71        AC H0V1I5.1
#=GS G3QLH0_GORGO/42-71        AC G3QLH0.1
#=GS F6SQP1_XENTR/42-71        AC F6SQP1.1
#=GS M3YFG0_MUSPF/39-68        AC M3YFG0.1
#=GS G3WJT8_SARHA/39-68        AC G3WJT8.1
#=GS EZH1_HUMAN/39-68          AC Q92800.2
#=GS A0A0N4SUQ7_MOUSE/39-68    AC A0A0N4SUQ7.1
#=GS I3M2Z1_ICTTR/40-69        AC I3M2Z1.1
#=GS G3TVT8_LOXAF/39-68        AC G3TVT8.1
#=GS EZH2_XENTR/39-68          AC Q28D84.1
#=GS H2LD32_ORYLA/43-72        AC H2LD32.1
#=GS A0A091PPZ2_HALAL/27-56    AC A0A091PPZ2.1
#=GS A0A0R4J1C0_MOUSE/42-71    AC A0A0R4J1C0.1
#=GS A0A093R550_PHACA/41-70    AC A0A093R550.1
#=GS K7EJU6_HUMAN/39-68        AC K7EJU6.1
#=GS A0A093CF38_9AVES/42-71    AC A0A093CF38.1
#=GS K7EK66_HUMAN/39-68        AC K7EK66.1
#=GS M4A3W8_XIPMA/61-90        AC M4A3W8.1
#=GS V8NEQ4_OPHHA/48-77        AC V8NEQ4.1
#=GS Q4TFL9_TETNG/1-30         AC Q4TFL9.1
A0A091PE45_LEPDC/27-56               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
F6ZEX1_MACMU/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
A0A096MIJ9_POEFO/45-74               ..KSMFNSNRQKIVERTDTLNQEWKTRRIQPV.
A0A091KFD5_9GRUI/42-71               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
F1QQ58_DANRE/39-68                   ..KSMFSSNRQKILERTDILNQEWKLRRIQPV.
I3L7H6_PIG/39-68                     ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
E1BD02_BOVIN/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
A0A093FZC6_PICPB/1-30                .q-ALFVANFAKVHEKTQLLNEDWKKLRVQPV.
H0X2K5_OTOGA/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
A0A0F8B6T2_LARCR/119-148             ..KSMFNTNRQKIMERTDILNQEWKTRRIQPV.
G3GXG1_CRIGR/39-68                   ..KTMFSSNRQKILERTETLNQEWKQRRIQPV.
F1LZH3_RAT/39-68                     ..KALYVANFAKVQEKTQLLNEEWKKLRVQPV.
G5B4F8_HETGA/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRVQPV.
H3C8R8_TETNG/44-73                   ..KSMFSTDRQKIMERTDIWNQEWKTRRIQPV.
H2LHB3_ORYLA/25-54                   ..KTLFSSNREKIEQQTTVLNSEWSTLKIQSI.
A0A093GTX8_TYTAL/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
H3C8Y8_TETNG/39-68                   ..KSMFSTDRQKIMERTDIWNQEWKTRRIQPV.
EZH2_MOUSE/39-68                     ..KTMFSSNRQKILERTETLNQEWKQRRIQPV.
#=GR EZH2_MOUSE/39-68          SS    ..X-HHHHHHHHHHHHHHHHHHHHHH------.
F6ZGV1_XENTR/40-68                   mf---YVENLTKAQERAHLLNEDWKKLRVQPI.
H2SFW8_TAKRU/39-68                   ..KSMFSTNRQKIVERTDILNQEWKTRRIQPV.
W5N725_LEPOC/39-68                   ..KSMFNSNRQKILERTDILNQEWKLRRIQPV.
H2UN45_TAKRU/25-54                   ..KALFMSNRRKIEQQTNVLNAEWSALRIQSI.
U3K6U9_FICAL/39-68                   ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
L5K0U5_PTEAL/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
A0A099ZXB0_CHAVO/27-56               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
F6YRI3_MONDO/40-69                   ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
E2R6Q2_CANLF/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
K7EIH5_HUMAN/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A091FNP4_9AVES/27-56               ..KALFVANFAKVHEKTRILNEDWKKLRVQPV.
G1LJS4_AILME/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A087QHS2_APTFO/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
H2UN46_TAKRU/25-54                   ..KALFMSNRRKIEQQTNVLNAEWSALRIQSI.
A0A091P149_HALAL/42-71               ..KSMFNSNRQKIMERTEILNQEWKQRRIQPV.
G1KPU3_ANOCA/44-73                   ..KALFASNYAKVQEKLDILNDDWKNLRVQPI.
H3DQW4_TETNG/1-30                    .r-SMFSTDRQKIMERTDIWNQEWKTRRIQPV.
A0A094KUX9_ANTCR/42-71               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
G1RM60_NOMLE/10-33                   .k-------FAKVQEKTQILNEEWKKLRVQPV.
EZH1_PONAB/39-68                     ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
G3P0V9_GASAC/45-74                   ..KTLFMSNRKKIEQQTNLLNAEWSRLRIQSI.
G3XAL2_HUMAN/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
K7EPC0_HUMAN/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
Q29RB7_DANRE/45-74                   ..KALFQSNRRKIEVGTELLNEEWSKLRIQSI.
A0A093PJ75_9PASS/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
H2UN48_TAKRU/25-54                   ..KALFMSNRRKIEQQTNVLNAEWSALRIQSI.
E1C0W5_CHICK/39-68                   ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
H2UN49_TAKRU/49-78                   ..KALFMSNRRKIEQQTNVLNAEWSALRIQSI.
H3AXZ3_LATCH/55-84                   ..KSLFTANRNKVKERTEVLNEDWKKLRVQP-t
A0A0A0A1R6_CHAVO/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
I3IY41_ORENI/25-54                   ..KTLFMSNRQKIEQQTNILNTEWSKLRIQSI.
G1MY19_MELGA/39-68                   ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
H3D2A7_TETNG/41-70                   ..KALFMSNRQKIEQQTNLLNAEWSALRIQSI.
EZH1_MOUSE/39-68                     ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
M4ACI0_XIPMA/39-68                   ..KSMFNSNRQKIVERTDTLNQEWKTRRIQPV.
A0A151PBG5_ALLMI/44-73               ..KALFVTNFAKVQEKTQLLNEEWKRLRVQPV.
G1KPH4_ANOCA/42-71                   ..KSMFNSNRQKIQERTEILNQEWKQRRIQPV.
#=GR G1KPH4_ANOCA/42-71        SS    ..HHHHHHHHHHHHHHHHHHHHHHHT--B---.
F6X2U8_ORNAN/52-81                   ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
I3M721_ICTTR/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
A0A091R240_MERNU/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A093LKV5_EURHL/41-70               ..KALFVANFAKVHEKTQMLNEDWKKLRVQPV.
M3WIA3_FELCA/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A096P5U8_PAPAN/39-68               ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A094M2E6_9AVES/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A151P243_ALLMI/96-125              ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A087XF77_POEFO/39-68               ..KSMFNSNRQKIVERTDTLNQEWKTRRIQPV.
A0A091IKZ5_9AVES/27-56               ..KALFVANFAKVHEKTQILNEAWKKLRVQPV.
A0A091NS73_APAVI/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A091HQU7_CALAN/25-54               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
U3ISV6_ANAPL/72-101                  ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
E9PDH6_HUMAN/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
A0A091IK45_CALAN/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A087QJA0_APTFO/27-56               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
K7ESX8_PONAB/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H2QD33_PANTR/42-71                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
W5NZD9_SHEEP/42-71                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A0D9S1H8_CHLSB/39-68               ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
G1MRP0_MELGA/42-71                   ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
H2PNY7_PONAB/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
M7BXG7_CHEMY/100-129                 ..KALFVANFAKVQEKTQILNEDWKKLRVQPV.
A0A096N0B2_PAPAN/39-68               ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
G7P1J2_MACFA/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
W5KZK5_ASTMX/48-77                   ..KALFISNRQKIELRTDLLNEEWSKLRIQSI.
A0A0R4IP69_DANRE/39-68               ..KSMFSSNRQKILERTDILNQEWKLRRIQPV.
A0A0Q3M8J4_AMAAE/39-68               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
K7G9J0_PELSI/54-83                   ..KSMFNSNRQKILERTEILNQEWKLRRIQPV.
L9JZV6_TUPCH/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
H3C7G6_TETNG/1-30                    .r-SMFSTDRQKIMERTDIWNQEWKTRRIQPV.
F6WSH0_HORSE/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H0X1I6_OTOGA/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A091H9K6_BUCRH/42-71               ..KSMFNSNRQKIVERTEILNQEWKQRRIQPV.
A0A093G904_PICPB/42-71               ..KGMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A091GH95_9AVES/41-70               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A091M0L3_CARIC/42-71               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
F7EPP0_CALJA/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
B5DFE2_RAT/39-68                     ..KTMFSSNRQKILERTETLNQEWKQRRIQPV.
F6VUP3_CALJA/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H0VLN2_CAVPO/39-68                   ..KALYVANFAKVQEKTQILNEEWKKRRVQPV.
G5BDP3_HETGA/66-95                   ..KALYVANFAKVQEKTQILSEEWKQRRVQPV.
I3KMB2_ORENI/39-68                   ..KSMFNSNRQKIMERTDILNQEWKTRRIQPV.
F1PG04_CANLF/42-71                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
L5JTD3_PTEAL/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
E9PWK3_MOUSE/39-68                   ..KTMFSSNRQKILERTETLNQEWKQRRIQPV.
G3NPN1_GASAC/39-68                   ..KSMFNTNRQKIVDRTDILNQEWKTRRIQPV.
F7AIG6_MONDO/39-68                   ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
H2UN47_TAKRU/25-54                   ..KALFMSNRRKIEQQTNVLNAEWSALRIQSI.
H0YU73_TAEGU/42-71                   ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
F6QA88_CALJA/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
H2QVK6_PANTR/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
A0A093FUR7_GAVST/27-56               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
A0A093IAL0_FULGA/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
F6Q6T3_CALJA/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
W5N3Q8_LEPOC/177-205                 sq---FMANRSKIKEKTELLNDEWSNLRIQPI.
F1NBM3_CHICK/39-68                   ..KALFVANFAKVHEKTRILNEDWKKLRVQPV.
H3CF02_TETNG/39-68                   ..KSMFSTNRQKIMERTDILNQEWKTRRIQPV.
F7HE52_MACMU/79-108                  ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
A0A093FV98_TYTAL/41-70               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
A0A091E603_CORBR/25-54               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
F6WCU8_CALJA/39-67                   ..-SMFSSNRQKILERTEILNQEWKQRRIQPV.
H3AXZ4_LATCH/39-68                   ..KSLFTANRNKVKERTEVLNEDWKKLRVQP-t
G3S979_GORGO/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
G1NY06_MYOLU/42-71                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
A0A093TN98_PHACA/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
G1L7Y5_AILME/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
F7F310_CALJA/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
A0A091VLE3_OPIHO/42-71               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
A0A091KTP8_9GRUI/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A091MBM1_CARIC/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A091IN18_9AVES/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
J9P0Q3_CANLF/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
F7EPM9_CALJA/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
A0A091XNZ1_OPIHO/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
G8F640_MACFA/1-29                    ..-ALYVANFAKVQEKTQILNEEWKKLRVQPV.
G3RFW0_GORGO/42-71                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H0ZUE4_TAEGU/41-70                   ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
EZH2_DANRE/39-68                     ..KSMFSSNRQKILERTDILNQEWKLRRIQPV.
F7B7S5_MACMU/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A099YX73_TINGU/27-56               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
F7BXB4_MONDO/59-88                   ..KALFVANFAKVQEKTQILNEDWKRLRIQPV.
A0A091D4Y5_FUKDA/39-68               ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
R4GB81_ANOCA/39-68                   ..KSMFNSNRQKIQERTEILNQEWKQRRIQPV.
A0A091GQH5_BUCRH/41-70               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
U3JD86_FICAL/44-73                   ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
A0A151P238_ALLMI/96-125              ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A091EQF7_CORBR/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
S7MMW0_MYOBR/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H3CEU8_TETNG/39-68                   ..KSMFSTDRQKIMERTDIWNQEWKTRRIQPV.
G1SQ77_RABIT/44-73                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
L9LD52_TUPCH/75-103                  .r--MFSSNRQKILERTEILNQEWKQRRIQPV.
A0A087Y758_POEFO/61-90               ..KSLFMSNRQKIELQTNLLNTEWSKLRIQAI.
F6WSU9_HORSE/41-70                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
F7ANW1_ORNAN/94-123                  ..KALFVANLAKVQEKTQLLNEAWKELRVQPV.
G3WZR9_SARHA/39-68                   ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A091N1J7_9PASS/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A0Q3PUX6_AMAAE/92-121              ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A099Z7D8_TINGU/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
W5QC07_SHEEP/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
G1SFW6_RABIT/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H3ANA1_LATCH/42-71                   ..KSMFNSNRQKIQEKTEILNQEWKQRRIQPV.
A0A0A0MSY9_HUMAN/39-68               ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
F1S1G9_PIG/39-68                     ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
F8W619_DANRE/45-74                   ..KALFQSNRRKIEVGTELLNEEWSKLRIQSI.
G3HLY5_CRIGR/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A087VQ59_BALRE/42-71               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
G3SNT7_LOXAF/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
A0A091MQ77_9PASS/25-54               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
F6YRR3_CALJA/42-71                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
K7EM79_HUMAN/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
I3IY40_ORENI/57-86                   ..KTLFMSNRQKIEQQTNILNTEWSKLRIQSI.
W5LQ79_ASTMX/39-68                   ..KSMFNSNRQKILERTDILNQEWKLRRIQPV.
A0A093PW62_9PASS/25-54               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
E7FFB7_DANRE/45-74                   ..KALFQSNRRKIEVGTELLNEEWSKLRIQSI.
A0A094KII5_ANTCR/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
F6SP16_MONDO/39-68                   ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
EZH2_HUMAN/39-68                     ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
#=GR EZH2_HUMAN/39-68          SS    ..HHHHHHHHHHHHHHHHHHHHHHHH------.
A0A0P7YN30_9TELE/39-68               ..KSMFNSNRQKILERTDILNQEWKLRRIQPV.
A0A0R4IDP8_DANRE/45-74               ..KALFQSNRRKIEVGTELLNEEWSKLRIQSI.
S7N8Q1_MYOBR/43-72                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A093F1L1_GAVST/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
M7BVS3_CHEMY/39-68                   ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A091JS62_COLST/25-54               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A093I325_STRCA/42-71               ..KSMFNSNRQKILERTEILNQEWKLRRIQPV.
A0A091DDG6_FUKDA/39-68               ..KALYVANFAKVQEKTQILNEEWKQRRVQPV.
A0A093IPV2_EURHL/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A091LD24_CATAU/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
D3Z774_MOUSE/39-68                   ..KTMFSSNRQKILERTETLNQEWKQRRIQPV.
G1P1J7_MYOLU/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A0P7Z1C9_9TELE/44-73               ..KSMFSLNRQKIIDRTDILNQEWKNRRIQSV.
A0A091SXQ2_9AVES/42-71               ..KALFVANFAKVHEKTQILNEAWKKLRVQPV.
V8NTZ9_OPHHA/61-90                   ..KNLFVSNFTKIQEKINILNDDWKKLRVQPI.
K7GH72_PELSI/39-68                   ..KALFVTNFAKVQEKTQILNEEWKNLRVQPV.
A0A0D9R3X6_CHLSB/39-68               ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
S9XJ27_CAMFR/49-78                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A087VB36_BALRE/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
Q6AXH7_MOUSE/39-68                   ..KTMFSSNRQKILERTETLNQEWKQRRIQPV.
K7ENP2_HUMAN/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A0P7UPN2_9TELE/46-75               ..KSLFMSNRRKIKERTNLLNDEWLKLRIQPI.
A0A091VA65_NIPNI/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
M3W9W8_FELCA/2-31                    ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
G3WZR8_SARHA/41-70                   ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
H2UN44_TAKRU/25-54                   ..KALFMSNRRKIEQQTNVLNAEWSALRIQSI.
G5CA03_HETGA/124-153                 ..KALYVANFAKVQEKTQILNEEWKQRRVQPV.
F6ZEW3_MACMU/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
X1WHS1_DANRE/39-68                   ..KSMFSSNRQKILERTDILNQEWKLRRIQPV.
EZH1_BOVIN/39-68                     ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
G1QTY8_NOMLE/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
G3T5L6_LOXAF/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
G3PG18_GASAC/39-68                   ..KSMFNTNRQKIVDRTDILNQEWKTRRIQPV.
H0V1I5_CAVPO/42-71                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
G3QLH0_GORGO/42-71                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
F6SQP1_XENTR/42-71                   ..KSMFNTNRQKIMERTEILNQEWKQRRIQPV.
M3YFG0_MUSPF/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
G3WJT8_SARHA/39-68                   ..KALFVANFAKVQEKTQILNEDWKKLRIQPV.
EZH1_HUMAN/39-68                     ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A0N4SUQ7_MOUSE/39-68               ..KTMFSSNRQKILERTETLNQEWKQRRIQPV.
I3M2Z1_ICTTR/40-69                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
G3TVT8_LOXAF/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
EZH2_XENTR/39-68                     ..KSMFNTNRQKIMERTEILNQEWKQRRIQPV.
H2LD32_ORYLA/43-72                   ..KGMFNSNRQKIMERTDILNQEWKTRRIQPI.
A0A091PPZ2_HALAL/27-56               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
A0A0R4J1C0_MOUSE/42-71               ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A093R550_PHACA/41-70               ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
K7EJU6_HUMAN/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A093CF38_9AVES/42-71               ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
K7EK66_HUMAN/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
M4A3W8_XIPMA/61-90                   ..KSLFMSNRQKIELQTNLLNTEWSKLRIQAI.
V8NEQ4_OPHHA/48-77                   ..KSMFNYNRQKIQERTEILNQEWKQRRIQPV.
Q4TFL9_TETNG/1-30                    .r-SMFSTDRQKIMERTDIWNQEWKTRRSQPV.
#=GC SS_cons                         ..HHHHHHHHHHHHHHHHHHHHHHHH--B---.
#=GC seq_cons                        ..KuhFsoNRpKIhE+TpILNpEWKphRIQPV.
//