GenomeNet

Database: Pfam
Entry: EZH2_WD-Binding
LinkDB: EZH2_WD-Binding
Original site: EZH2_WD-Binding 
#=GF ID   EZH2_WD-Binding
#=GF AC   PF11616.5
#=GF DE   WD repeat binding protein EZH2
#=GF AU   Pollington J
#=GF SE   pdb_2qxv
#=GF GA   25.00 25.00;
#=GF TC   44.30 43.50;
#=GF NC   20.20 18.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   17937919
#=GF RT   Structural basis of EZH2 recognition by EED. 
#=GF RA   Han Z, Xing X, Hu M, Zhang Y, Liu P, Chai J; 
#=GF RL   Structure. 2007;15:1306-1315.
#=GF DR   INTERPRO; IPR021654;
#=GF CC   This family of proteins represents Enhancer of zest homolog 2,
#=GF CC   (EZH2) a 30 residue peptide which binds to a WD-repeat domain of
#=GF CC   EED by residues 39-68. EED is a component of PRC2 complex which
#=GF CC   is involved in gene expression [1]. This interaction is required
#=GF CC   for the HMTase activity of PCR2 [1].
#=GF SQ   155
#=GS F6ZEX1_MACMU/39-68      AC F6ZEX1.1
#=GS A0A096MIJ9_POEFO/45-74  AC A0A096MIJ9.1
#=GS F1QQ58_DANRE/39-68      AC F1QQ58.1
#=GS I3L7H6_PIG/39-68        AC I3L7H6.1
#=GS E1BD02_BOVIN/39-68      AC E1BD02.2
#=GS H0X2K5_OTOGA/39-68      AC H0X2K5.1
#=GS G3GXG1_CRIGR/39-68      AC G3GXG1.1
#=GS F1LZH3_RAT/39-68        AC F1LZH3.2
#=GS G5B4F8_HETGA/39-68      AC G5B4F8.1
#=GS H3C8R8_TETNG/44-73      AC H3C8R8.1
#=GS H2LHB3_ORYLA/25-54      AC H2LHB3.1
#=GS H3C8Y8_TETNG/39-68      AC H3C8Y8.1
#=GS EZH2_MOUSE/39-68        AC Q61188.2
#=GS EZH2_MOUSE/39-68        DR PDB; 2QXV B; 40-68;
#=GS F6ZGV1_XENTR/40-68      AC F6ZGV1.1
#=GS H2SFW8_TAKRU/39-68      AC H2SFW8.1
#=GS W5N725_LEPOC/39-68      AC W5N725.1
#=GS H2UN45_TAKRU/25-54      AC H2UN45.1
#=GS U3K6U9_FICAL/39-68      AC U3K6U9.1
#=GS L5K0U5_PTEAL/39-68      AC L5K0U5.1
#=GS F6YRI3_MONDO/40-69      AC F6YRI3.1
#=GS E2R6Q2_CANFA/39-68      AC E2R6Q2.1
#=GS K7EIH5_HUMAN/39-68      AC K7EIH5.1
#=GS G1LJS4_AILME/39-68      AC G1LJS4.1
#=GS H2UN46_TAKRU/25-54      AC H2UN46.1
#=GS G1KPU3_ANOCA/44-73      AC G1KPU3.2
#=GS H3DQW4_TETNG/1-30       AC H3DQW4.1
#=GS G1RM60_NOMLE/10-33      AC G1RM60.2
#=GS EZH1_PONAB/39-68        AC Q5RDS6.1
#=GS G3P0V9_GASAC/45-74      AC G3P0V9.1
#=GS G3XAL2_HUMAN/39-68      AC G3XAL2.1
#=GS K7EPC0_HUMAN/39-68      AC K7EPC0.1
#=GS Q29RB7_DANRE/45-74      AC Q29RB7.1
#=GS H2UN48_TAKRU/25-54      AC H2UN48.1
#=GS E1C0W5_CHICK/39-68      AC E1C0W5.2
#=GS H2UN49_TAKRU/49-78      AC H2UN49.1
#=GS H3AXZ3_LATCH/55-84      AC H3AXZ3.1
#=GS I3IY41_ORENI/25-54      AC I3IY41.1
#=GS G1MY19_MELGA/39-68      AC G1MY19.2
#=GS H3D2A7_TETNG/41-70      AC H3D2A7.1
#=GS EZH1_MOUSE/39-68        AC P70351.1
#=GS M4ACI0_XIPMA/39-68      AC M4ACI0.1
#=GS G1KPH4_ANOCA/42-71      AC G1KPH4.1
#=GS F6X2U8_ORNAN/52-81      AC F6X2U8.2
#=GS I3M721_SPETR/39-68      AC I3M721.1
#=GS M3WIA3_FELCA/39-68      AC M3WIA3.1
#=GS A0A096P5U8_PAPAN/39-68  AC A0A096P5U8.1
#=GS A0A087XF77_POEFO/39-68  AC A0A087XF77.2
#=GS U3ISV6_ANAPL/72-101     AC U3ISV6.1
#=GS E9PDH6_HUMAN/39-68      AC E9PDH6.1
#=GS K7ESX8_PONAB/39-68      AC K7ESX8.1
#=GS H2QD33_PANTR/42-71      AC H2QD33.1
#=GS W5NZD9_SHEEP/42-71      AC W5NZD9.1
#=GS A0A0D9S1H8_CHLSB/39-68  AC A0A0D9S1H8.1
#=GS G1MRP0_MELGA/42-71      AC G1MRP0.2
#=GS H2PNY7_PONAB/39-68      AC H2PNY7.1
#=GS M7BXG7_CHEMY/100-129    AC M7BXG7.1
#=GS A0A096N0B2_PAPAN/39-68  AC A0A096N0B2.1
#=GS G7P1J2_MACFA/39-68      AC G7P1J2.1
#=GS W5KZK5_ASTMX/48-77      AC W5KZK5.1
#=GS L9JZV6_TUPCH/39-68      AC L9JZV6.1
#=GS H3C7G6_TETNG/1-30       AC H3C7G6.1
#=GS F6WSH0_HORSE/39-68      AC F6WSH0.1
#=GS H0X1I6_OTOGA/39-68      AC H0X1I6.1
#=GS F7EPP0_CALJA/39-68      AC F7EPP0.1
#=GS B5DFE2_RAT/39-68        AC B5DFE2.1
#=GS K7EM79_HUMAN/39-68      AC K7EM79.5
#=GS F6VUP3_CALJA/39-68      AC F6VUP3.1
#=GS H0VLN2_CAVPO/39-68      AC H0VLN2.1
#=GS G5BDP3_HETGA/66-95      AC G5BDP3.1
#=GS I3KMB2_ORENI/39-68      AC I3KMB2.1
#=GS F1PG04_CANFA/42-71      AC F1PG04.2
#=GS L5JTD3_PTEAL/39-68      AC L5JTD3.1
#=GS E9PWK3_MOUSE/39-68      AC E9PWK3.1
#=GS G3NPN1_GASAC/39-68      AC G3NPN1.1
#=GS F7AIG6_MONDO/39-68      AC F7AIG6.1
#=GS H2UN47_TAKRU/25-54      AC H2UN47.1
#=GS H0YU73_TAEGU/42-71      AC H0YU73.1
#=GS F6QA88_CALJA/39-68      AC F6QA88.1
#=GS H2QVK6_PANTR/39-68      AC H2QVK6.1
#=GS F6Q6T3_CALJA/39-68      AC F6Q6T3.1
#=GS W5N3Q8_LEPOC/177-205    AC W5N3Q8.1
#=GS F1NBM3_CHICK/39-68      AC F1NBM3.2
#=GS H3CF02_TETNG/39-68      AC H3CF02.1
#=GS F7HE52_MACMU/79-108     AC F7HE52.1
#=GS F6WCU8_CALJA/39-67      AC F6WCU8.1
#=GS G3S979_GORGO/39-68      AC G3S979.1
#=GS H3AXZ4_LATCH/39-68      AC H3AXZ4.1
#=GS G1NY06_MYOLU/42-71      AC G1NY06.1
#=GS F7F310_CALJA/39-68      AC F7F310.1
#=GS G1L7Y5_AILME/39-68      AC G1L7Y5.1
#=GS J9P0Q3_CANFA/39-68      AC J9P0Q3.1
#=GS F7EPM9_CALJA/39-68      AC F7EPM9.1
#=GS G8F640_MACFA/1-29       AC G8F640.1
#=GS G3RFW0_GORGO/42-71      AC G3RFW0.1
#=GS H0ZUE4_TAEGU/41-70      AC H0ZUE4.1
#=GS EZH2_DANRE/39-68        AC Q08BS4.1
#=GS F7B7S5_MACMU/39-68      AC F7B7S5.1
#=GS F7BXB4_MONDO/59-88      AC F7BXB4.2
#=GS A0A091D4Y5_FUKDA/39-68  AC A0A091D4Y5.1
#=GS R4GB81_ANOCA/39-68      AC R4GB81.1
#=GS U3JD86_FICAL/44-73      AC U3JD86.1
#=GS H3CEU8_TETNG/39-68      AC H3CEU8.1
#=GS G1SQ77_RABIT/44-73      AC G1SQ77.2
#=GS L9LD52_TUPCH/75-103     AC L9LD52.1
#=GS A0A087Y758_POEFO/61-90  AC A0A087Y758.2
#=GS F7ANW1_ORNAN/94-123     AC F7ANW1.2
#=GS F6WSU9_HORSE/41-70      AC F6WSU9.1
#=GS G3WZR9_SARHA/39-68      AC G3WZR9.1
#=GS W5QC07_SHEEP/39-68      AC W5QC07.1
#=GS H3ANA1_LATCH/42-71      AC H3ANA1.1
#=GS G1SFW6_RABIT/39-68      AC G1SFW6.2
#=GS F1S1G9_PIG/39-68        AC F1S1G9.2
#=GS A0A0A0MSY9_HUMAN/39-68  AC A0A0A0MSY9.1
#=GS F8W619_DANRE/45-74      AC F8W619.1
#=GS G3HLY5_CRIGR/39-68      AC G3HLY5.1
#=GS G3SNT7_LOXAF/39-68      AC G3SNT7.1
#=GS F6YRR3_CALJA/42-71      AC F6YRR3.1
#=GS I3IY40_ORENI/57-86      AC I3IY40.1
#=GS W5LQ79_ASTMX/39-68      AC W5LQ79.1
#=GS F6SP16_MONDO/39-68      AC F6SP16.1
#=GS EZH2_HUMAN/39-68        AC Q15910.2
#=GS M7BVS3_CHEMY/39-68      AC M7BVS3.1
#=GS A0A091DDG6_FUKDA/39-68  AC A0A091DDG6.1
#=GS D3Z774_MOUSE/39-68      AC D3Z774.1
#=GS G1P1J7_MYOLU/39-68      AC G1P1J7.1
#=GS V8NTZ9_OPHHA/61-90      AC V8NTZ9.1
#=GS E7FFB7_DANRE/45-74      AC E7FFB7.1
#=GS A0A0D9R3X6_CHLSB/39-68  AC A0A0D9R3X6.1
#=GS Q6AXH7_MOUSE/39-68      AC Q6AXH7.1
#=GS K7ENP2_HUMAN/39-68      AC K7ENP2.1
#=GS M3W9W8_FELCA/2-31       AC M3W9W8.1
#=GS G3WZR8_SARHA/41-70      AC G3WZR8.1
#=GS G5CA03_HETGA/124-153    AC G5CA03.1
#=GS F6ZEW3_MACMU/39-68      AC F6ZEW3.1
#=GS H2UN44_TAKRU/25-54      AC H2UN44.1
#=GS X1WHS1_DANRE/39-68      AC X1WHS1.1
#=GS EZH1_BOVIN/39-68        AC A7E2Z2.2
#=GS G1QTY8_NOMLE/39-68      AC G1QTY8.2
#=GS G3T5L6_LOXAF/39-68      AC G3T5L6.1
#=GS G3PG18_GASAC/39-68      AC G3PG18.1
#=GS H0V1I5_CAVPO/42-71      AC H0V1I5.1
#=GS G3QLH0_GORGO/42-71      AC G3QLH0.1
#=GS M3YFG0_MUSPF/39-68      AC M3YFG0.1
#=GS F6SQP1_XENTR/42-71      AC F6SQP1.1
#=GS G3WJT8_SARHA/39-68      AC G3WJT8.1
#=GS EZH1_HUMAN/39-68        AC Q92800.2
#=GS EZH2_XENTR/39-68        AC Q28D84.1
#=GS G3TVT8_LOXAF/39-68      AC G3TVT8.1
#=GS I3M2Z1_SPETR/40-69      AC I3M2Z1.1
#=GS H2LD32_ORYLA/43-72      AC H2LD32.1
#=GS K7EJU6_HUMAN/39-68      AC K7EJU6.1
#=GS K7EK66_HUMAN/39-68      AC K7EK66.1
#=GS M4A3W8_XIPMA/61-90      AC M4A3W8.1
#=GS V8NEQ4_OPHHA/48-77      AC V8NEQ4.1
#=GS Q4TFL9_TETNG/1-30       AC Q4TFL9.1
F6ZEX1_MACMU/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
A0A096MIJ9_POEFO/45-74             ..KSMFNSNRQKIVERTDTLNQEWKTRRIQPV.
F1QQ58_DANRE/39-68                 ..KSMFSSNRQKILERTDILNQEWKLRRIQPV.
I3L7H6_PIG/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
E1BD02_BOVIN/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H0X2K5_OTOGA/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
G3GXG1_CRIGR/39-68                 ..KTMFSSNRQKILERTETLNQEWKQRRIQPV.
F1LZH3_RAT/39-68                   ..KALYVANFAKVQEKTQLLNEEWKKLRVQPV.
G5B4F8_HETGA/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRVQPV.
H3C8R8_TETNG/44-73                 ..KSMFSTDRQKIMERTDIWNQEWKTRRIQPV.
H2LHB3_ORYLA/25-54                 ..KTLFSSNREKIEQQTTVLNSEWSTLKIQSI.
H3C8Y8_TETNG/39-68                 ..KSMFSTDRQKIMERTDIWNQEWKTRRIQPV.
EZH2_MOUSE/39-68                   ..KTMFSSNRQKILERTETLNQEWKQRRIQPV.
#=GR EZH2_MOUSE/39-68        SS    ..HHHHHHHHHHHHHHHHHHHHHH------XX.
F6ZGV1_XENTR/40-68                 mf---YVENLTKAQERAHLLNEDWKKLRVQPI.
H2SFW8_TAKRU/39-68                 ..KSMFSTNRQKIVERTDILNQEWKTRRIQPV.
W5N725_LEPOC/39-68                 ..KSMFNSNRQKILERTDILNQEWKLRRIQPV.
H2UN45_TAKRU/25-54                 ..KALFMSNRRKIEQQTNVLNAEWSALRIQSI.
U3K6U9_FICAL/39-68                 ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
L5K0U5_PTEAL/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
F6YRI3_MONDO/40-69                 ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
E2R6Q2_CANFA/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
K7EIH5_HUMAN/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
G1LJS4_AILME/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
H2UN46_TAKRU/25-54                 ..KALFMSNRRKIEQQTNVLNAEWSALRIQSI.
G1KPU3_ANOCA/44-73                 ..KALFASNYAKVQEKLDILNDDWKNLRVQPI.
H3DQW4_TETNG/1-30                  .r-SMFSTDRQKIMERTDIWNQEWKTRRIQPV.
G1RM60_NOMLE/10-33                 .k-------FAKVQEKTQILNEEWKKLRVQPV.
EZH1_PONAB/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
G3P0V9_GASAC/45-74                 ..KTLFMSNRKKIEQQTNLLNAEWSRLRIQSI.
G3XAL2_HUMAN/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
K7EPC0_HUMAN/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
Q29RB7_DANRE/45-74                 ..KALFQSNRRKIEVGTELLNEEWSKLRIQSI.
H2UN48_TAKRU/25-54                 ..KALFMSNRRKIEQQTNVLNAEWSALRIQSI.
E1C0W5_CHICK/39-68                 ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
H2UN49_TAKRU/49-78                 ..KALFMSNRRKIEQQTNVLNAEWSALRIQSI.
H3AXZ3_LATCH/55-84                 ..KSLFTANRNKVKERTEVLNEDWKKLRVQP-t
I3IY41_ORENI/25-54                 ..KTLFMSNRQKIEQQTNILNTEWSKLRIQSI.
G1MY19_MELGA/39-68                 ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
H3D2A7_TETNG/41-70                 ..KALFMSNRQKIEQQTNLLNAEWSALRIQSI.
EZH1_MOUSE/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
M4ACI0_XIPMA/39-68                 ..KSMFNSNRQKIVERTDTLNQEWKTRRIQPV.
G1KPH4_ANOCA/42-71                 ..KSMFNSNRQKIQERTEILNQEWKQRRIQPV.
F6X2U8_ORNAN/52-81                 ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
I3M721_SPETR/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
M3WIA3_FELCA/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A096P5U8_PAPAN/39-68             ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A087XF77_POEFO/39-68             ..KSMFNSNRQKIVERTDTLNQEWKTRRIQPV.
U3ISV6_ANAPL/72-101                ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
E9PDH6_HUMAN/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
K7ESX8_PONAB/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H2QD33_PANTR/42-71                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
W5NZD9_SHEEP/42-71                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A0D9S1H8_CHLSB/39-68             ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
G1MRP0_MELGA/42-71                 ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
H2PNY7_PONAB/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
M7BXG7_CHEMY/100-129               ..KALFVANFAKVQEKTQILNEDWKKLRVQPV.
A0A096N0B2_PAPAN/39-68             ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
G7P1J2_MACFA/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
W5KZK5_ASTMX/48-77                 ..KALFISNRQKIELRTDLLNEEWSKLRIQSI.
L9JZV6_TUPCH/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
H3C7G6_TETNG/1-30                  .r-SMFSTDRQKIMERTDIWNQEWKTRRIQPV.
F6WSH0_HORSE/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H0X1I6_OTOGA/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
F7EPP0_CALJA/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
B5DFE2_RAT/39-68                   ..KTMFSSNRQKILERTETLNQEWKQRRIQPV.
K7EM79_HUMAN/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
F6VUP3_CALJA/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H0VLN2_CAVPO/39-68                 ..KALYVANFAKVQEKTQILNEEWKKRRVQPV.
G5BDP3_HETGA/66-95                 ..KALYVANFAKVQEKTQILSEEWKQRRVQPV.
I3KMB2_ORENI/39-68                 ..KSMFNSNRQKIMERTDILNQEWKTRRIQPV.
F1PG04_CANFA/42-71                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
L5JTD3_PTEAL/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
E9PWK3_MOUSE/39-68                 ..KTMFSSNRQKILERTETLNQEWKQRRIQPV.
G3NPN1_GASAC/39-68                 ..KSMFNTNRQKIVDRTDILNQEWKTRRIQPV.
F7AIG6_MONDO/39-68                 ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
H2UN47_TAKRU/25-54                 ..KALFMSNRRKIEQQTNVLNAEWSALRIQSI.
H0YU73_TAEGU/42-71                 ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
F6QA88_CALJA/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
H2QVK6_PANTR/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
F6Q6T3_CALJA/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
W5N3Q8_LEPOC/177-205               sq---FMANRSKIKEKTELLNDEWSNLRIQPI.
F1NBM3_CHICK/39-68                 ..KALFVANFAKVHEKTRILNEDWKKLRVQPV.
H3CF02_TETNG/39-68                 ..KSMFSTNRQKIMERTDILNQEWKTRRIQPV.
F7HE52_MACMU/79-108                ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
F6WCU8_CALJA/39-67                 ..-SMFSSNRQKILERTEILNQEWKQRRIQPV.
G3S979_GORGO/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H3AXZ4_LATCH/39-68                 ..KSLFTANRNKVKERTEVLNEDWKKLRVQP-t
G1NY06_MYOLU/42-71                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
F7F310_CALJA/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
G1L7Y5_AILME/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
J9P0Q3_CANFA/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
F7EPM9_CALJA/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
G8F640_MACFA/1-29                  ..-ALYVANFAKVQEKTQILNEEWKKLRVQPV.
G3RFW0_GORGO/42-71                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H0ZUE4_TAEGU/41-70                 ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
EZH2_DANRE/39-68                   ..KSMFSSNRQKILERTDILNQEWKLRRIQPV.
F7B7S5_MACMU/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
F7BXB4_MONDO/59-88                 ..KALFVANFAKVQEKTQILNEDWKRLRIQPV.
A0A091D4Y5_FUKDA/39-68             ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
R4GB81_ANOCA/39-68                 ..KSMFNSNRQKIQERTEILNQEWKQRRIQPV.
U3JD86_FICAL/44-73                 ..KALFVANFAKVHEKTQILNEDWKKLRVQPV.
H3CEU8_TETNG/39-68                 ..KSMFSTDRQKIMERTDIWNQEWKTRRIQPV.
G1SQ77_RABIT/44-73                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
L9LD52_TUPCH/75-103                .r--MFSSNRQKILERTEILNQEWKQRRIQPV.
A0A087Y758_POEFO/61-90             ..KSLFMSNRQKIELQTNLLNTEWSKLRIQAI.
F7ANW1_ORNAN/94-123                ..KALFVANLAKVQEKTQLLNEAWKELRVQPV.
F6WSU9_HORSE/41-70                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
G3WZR9_SARHA/39-68                 ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
W5QC07_SHEEP/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H3ANA1_LATCH/42-71                 ..KSMFNSNRQKIQEKTEILNQEWKQRRIQPV.
G1SFW6_RABIT/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
F1S1G9_PIG/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
A0A0A0MSY9_HUMAN/39-68             ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
F8W619_DANRE/45-74                 ..KALFQSNRRKIEVGTELLNEEWSKLRIQSI.
G3HLY5_CRIGR/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
G3SNT7_LOXAF/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
F6YRR3_CALJA/42-71                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
I3IY40_ORENI/57-86                 ..KTLFMSNRQKIEQQTNILNTEWSKLRIQSI.
W5LQ79_ASTMX/39-68                 ..KSMFNSNRQKILERTDILNQEWKLRRIQPV.
F6SP16_MONDO/39-68                 ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
EZH2_HUMAN/39-68                   ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
M7BVS3_CHEMY/39-68                 ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
A0A091DDG6_FUKDA/39-68             ..KALYVANFAKVQEKTQILNEEWKQRRVQPV.
D3Z774_MOUSE/39-68                 ..KTMFSSNRQKILERTETLNQEWKQRRIQPV.
G1P1J7_MYOLU/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
V8NTZ9_OPHHA/61-90                 ..KNLFVSNFTKIQEKINILNDDWKKLRVQPI.
E7FFB7_DANRE/45-74                 ..KALFQSNRRKIEVGTELLNEEWSKLRIQSI.
A0A0D9R3X6_CHLSB/39-68             ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
Q6AXH7_MOUSE/39-68                 ..KTMFSSNRQKILERTETLNQEWKQRRIQPV.
K7ENP2_HUMAN/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
M3W9W8_FELCA/2-31                  ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
G3WZR8_SARHA/41-70                 ..KSMFNSNRQKILERTEILNQEWKQRRIQPV.
G5CA03_HETGA/124-153               ..KALYVANFAKVQEKTQILNEEWKQRRVQPV.
F6ZEW3_MACMU/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
H2UN44_TAKRU/25-54                 ..KALFMSNRRKIEQQTNVLNAEWSALRIQSI.
X1WHS1_DANRE/39-68                 ..KSMFSSNRQKILERTDILNQEWKLRRIQPV.
EZH1_BOVIN/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
G1QTY8_NOMLE/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
G3T5L6_LOXAF/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
G3PG18_GASAC/39-68                 ..KSMFNTNRQKIVDRTDILNQEWKTRRIQPV.
H0V1I5_CAVPO/42-71                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
G3QLH0_GORGO/42-71                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
M3YFG0_MUSPF/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
F6SQP1_XENTR/42-71                 ..KSMFNTNRQKIMERTEILNQEWKQRRIQPV.
G3WJT8_SARHA/39-68                 ..KALFVANFAKVQEKTQILNEDWKKLRIQPV.
EZH1_HUMAN/39-68                   ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
EZH2_XENTR/39-68                   ..KSMFNTNRQKIMERTEILNQEWKQRRIQPV.
G3TVT8_LOXAF/39-68                 ..KSMFSSNRQKILERTEILNQEWKQRRIQPV.
I3M2Z1_SPETR/40-69                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
H2LD32_ORYLA/43-72                 ..KGMFNSNRQKIMERTDILNQEWKTRRIQPI.
K7EJU6_HUMAN/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
K7EK66_HUMAN/39-68                 ..KALYVANFAKVQEKTQILNEEWKKLRVQPV.
M4A3W8_XIPMA/61-90                 ..KSLFMSNRQKIELQTNLLNTEWSKLRIQAI.
V8NEQ4_OPHHA/48-77                 ..KSMFNYNRQKIQERTEILNQEWKQRRIQPV.
Q4TFL9_TETNG/1-30                  .r-SMFSTDRQKIMERTDIWNQEWKTRRSQPV.
#=GC SS_cons                       ..HHHHHHHHHHHHHHHHHHHHHH------XX.
#=GC seq_cons                      ..KuhFsoNRpKI.E+TpILNpEWKphRIQPV.
//
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