GenomeNet

Database: Pfam
Entry: EcoRII-N
LinkDB: EcoRII-N
Original site: EcoRII-N 
#=GF ID   EcoRII-N
#=GF AC   PF09217.9
#=GF DE   Restriction endonuclease EcoRII, N-terminal
#=GF AU   Sammut SJ
#=GF SE   pdb_1na6
#=GF GA   25.00 25.00;
#=GF TC   25.50 26.30;
#=GF NC   23.40 24.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   R.EcoRII
#=GF RN   [1]
#=GF RM   14659759
#=GF RT   Crystal structure of type IIE restriction endonuclease EcoRII
#=GF RT   reveals an autoinhibition mechanism by a novel effector-binding
#=GF RT   fold. 
#=GF RA   Zhou XE, Wang Y, Reuter M, Mucke M, Kruger DH, Meehan EJ, Chen
#=GF RA   L; 
#=GF RL   J Mol Biol. 2004;335:307-319.
#=GF DR   INTERPRO; IPR023372;
#=GF DR   SCOP; 1na6; fa;
#=GF CC   The N-terminal effector-binding domain of the Restriction
#=GF CC   Endonuclease EcoRII has a DNA recognition fold, allowing for
#=GF CC   binding to 5'-CCWGG sequences. It assumes a structure composed
#=GF CC   of an eight-stranded beta-sheet with the strands in the order of
#=GF CC   b2, b5, b4, b3, b7, b6, b1 and b8. They are mostly antiparallel
#=GF CC   to each other except that b3 is parallel to b7. Alternatively,
#=GF CC   it may also be viewed as consisting of two mini beta-sheets of
#=GF CC   four antiparallel beta-strands, sheet I from beta-strands b2,
#=GF CC   b5, b4, b3 and sheet II from strands b7, b6, b1, b8, folded into
#=GF CC   an open mixed beta-barrel with a novel topology. Sheet I has a
#=GF CC   simple Greek key motif while sheet II does not [1].
#=GF SQ   49
#=GS J9ZE30_LEPFM/14-167      AC J9ZE30.1
#=GS A0A0M0G4X2_9BACI/16-154  AC A0A0M0G4X2.1
#=GS R5UQ53_9BACT/12-135      AC R5UQ53.1
#=GS F2NVD3_TRES6/12-144      AC F2NVD3.1
#=GS A0A160F554_9BACI/17-146  AC A0A160F554.1
#=GS A0A0J5L1W0_PLUGE/12-164  AC A0A0J5L1W0.1
#=GS A0A0M7B9U7_9RHOB/3-97    AC A0A0M7B9U7.1
#=GS U7DBV3_9BACT/3-115       AC U7DBV3.1
#=GS H2CIA7_9LEPT/22-162      AC H2CIA7.1
#=GS A0A0F7HPZ5_9STAP/9-142   AC A0A0F7HPZ5.1
#=GS R9GMU6_9SPHI/12-118      AC R9GMU6.1
#=GS G9RPY3_9FIRM/12-137      AC G9RPY3.1
#=GS A0A100YQX9_9FIRM/14-134  AC A0A100YQX9.1
#=GS J0N5F7_9CLOT/12-136      AC J0N5F7.1
#=GS C5BFF1_EDWI9/13-166      AC C5BFF1.2
#=GS A0A0J9B3I8_9BACT/12-165  AC A0A0J9B3I8.1
#=GS A8G987_SERP5/12-169      AC A8G987.1
#=GS A0A142WRW3_9PLAN/7-117   AC A0A142WRW3.1
#=GS Q9JZ51_NEIMB/26-167      AC Q9JZ51.1
#=GS A0A0M4M5M9_9SPHN/1-118   AC A0A0M4M5M9.1
#=GS X7F2M9_9RHOB/1-97        AC X7F2M9.1
#=GS N9W5I5_9SPHN/2-91        AC N9W5I5.1
#=GS A0A142WTD2_9PLAN/12-173  AC A0A142WTD2.1
#=GS A8AM36_CITK8/13-166      AC A8AM36.1
#=GS S6GR81_9GAMM/3-136       AC S6GR81.1
#=GS A5FU96_ACICJ/14-166      AC A5FU96.1
#=GS D5QBY0_KOMHA/6-115       AC D5QBY0.1
#=GS R6ETE5_9FIRM/14-148      AC R6ETE5.1
#=GS E7GQT1_CLOSY/14-144      AC E7GQT1.1
#=GS A0A0K9GCN6_9BACI/16-155  AC A0A0K9GCN6.1
#=GS A0A098T281_9PSED/1-98    AC A0A098T281.1
#=GS B3EB37_GEOLS/3-105       AC B3EB37.1
#=GS A0A011U286_9RHIZ/14-168  AC A0A011U286.1
#=GS C4ZAA8_AGARV/13-138      AC C4ZAA8.1
#=GS A5P8H9_9SPHN/2-118       AC A5P8H9.1
#=GS A0A0E9N2X2_9BACT/12-102  AC A0A0E9N2X2.1
#=GS U2UYE2_9FIRM/14-133      AC U2UYE2.1
#=GS A0A0M4D460_9DELT/15-167  AC A0A0M4D460.1
#=GS A0A0W0YKK4_9GAMM/2-113   AC A0A0W0YKK4.1
#=GS R7B2S4_9CLOT/15-146      AC R7B2S4.1
#=GS A0A0G3UZF9_9ACTN/30-126  AC A0A0G3UZF9.1
#=GS R5GVJ7_9BACT/12-144      AC R5GVJ7.1
#=GS A3X5U6_9RHOB/2-97        AC A3X5U6.1
#=GS A0A085H7C2_9ENTR/27-180  AC A0A085H7C2.1
#=GS H2ISN5_RAHAC/12-169      AC H2ISN5.1
#=GS A9MS72_SALAR/13-166      AC A9MS72.1
#=GS R5UXG0_9BACT/13-149      AC R5UXG0.1
#=GS A0A062TW84_9RHOB/11-163  AC A0A062TW84.1
#=GS E2ZD29_9FIRM/15-79       AC E2ZD29.1
J9ZE30_LEPFM/14-167                 .......s-RRETLWFAKRLSANDTLANNAHQAGPYIPK..N.I.L.F..TL..FPSLDRPEDKN..PEVRFRLQIDSHQGERREIRAVWYNNRRRG.........KTRDEARITGFGGRSSPFLDPENTGALMLLVVPPGDN.....TQTSICRAWVCRNPSE.EDLLEDLIGP..VEPGKGFLWAP--ev..............................
A0A0M0G4X2_9BACI/16-154             ..akhigr------FYCKFVTANDVGLTNAHQEGIHISK..S.A.W.G..IF..FQEAGT-KGEN..KHRIVKIDIEGLYPFDSRVS--YYGK----.........GTRNEYRITRFWTN-SPFDKARQLGNLIIFLPMGGDN.....-----FKVYILDTDDE.IEL-------..-------------ftqtfslnlvnnnavynh..............
R5UQ53_9BACT/12-135                 ...vdkvq-----AAFCKFIYANDVGATGAHQDGIYIPK..N.C.W.S..LI..FDNPSE-KGVN..KDHFVKIRWKNNFETD--NRFIYYGK----.........GTRNEYRLTRFGKRFPFFQE-DNVGDLIIICRTE---.....----------------.----------..-------------ldyyfgfvlsadedidnffg............
F2NVD3_TRES6/12-144                 .....tan---SERIFCKFLSANDTGETGGHQSGIYIPK..N.S.V.P..LI..FDTPG-VKGEN..KEEFNKIKWQDDFETDAHFK--YYGQ----.........GTRNEYRITGFGRNF-PFLKPAFTGSLVIILKQKDSS.....-----YKGYVL-----.----------..-------------etedeieyfldyfgitpnet............
A0A160F554_9BACI/17-146             ...ktfgr------FYCKVISANDVDLTGGHQAGIYIAK..Q.A.W.N..IF..FEKKGK-KGEN..KDKFIKIYIDGYIP--FDSRVIYYGK----.........GTRNEYRLTRFWNQ-SPFHKEEQVGNLIIFIPVDQEN.....-----FKVWILDTEEE.IEL-------..-------------flntfslsmm......................
A0A0J5L1W0_PLUGE/12-164             .....atg---NYFLYIKRLSANDTGATGGHQVGLYIPS..G.I.V.A..EL..FPSIDNTKEQN..PSVFLNATYSSHVCSDSEARAIYYNGSFFG.........KTRNEKRITRWGPG-SPLQDPENTGGLSILAFEHEPG.....SDSKNVDVWVCKNPDE.EDIVESILGE..IIPGALRFGPAKE................................
A0A0M7B9U7_9RHOB/3-97               ..fetrsi--------TKVLSANDTGETGGHQAGILVPR..E.RrL.L..SF..FPSLNE-KDYN..PRAHLKF--VDASGLEWEFAFIYYNNKFFG.........GTRNEYRLTRM--------------------------.....----------------.----------..-------------trfireagla......................
U7DBV3_9BACT/3-115                  .trtnaie---------KMLSRNDTGETGGHQAGILIPK..K.PeI.L..SF..FPELNN-EEKN..PRFL--IAFHDHMGEQWSFSFIYYNNKFFG.........GTRNEYRLTGMTRYMS---------------------.....----------------.----------..-------------aynlksgdtltlsrdvngfysvk.........
H2CIA7_9LEPT/22-162                 ....gssd------AYLKFLSPNDLGLTGSHQAGIYLSR..E.S.A.P..LF..LEGKTVEKGEN..VEREVRIRFRGGNV---AARFVWYGK----.........-AKSECRLTRILPLFRPDPA-RLEGSLFILAAVPDDRpdslfENDSLFQCWIIESEDE.----------..-------------iravldflgitpaetn................
A0A0F7HPZ5_9STAP/9-142              ...rgigc------FFCKFLSANDTGANGSHQTGVYLNM..S.S.W.D..IF..FEGPIP-NNEI..KSRKVKINFNDE--TEFESRLVYYSS----.........--KKEFRITRFWTN-IFIPHTEMVGALILFIPMHIDE.....-----YKVYIFNTEE-.-EI-E-----..-------------efietfslslaenhmty...............
R9GMU6_9SPHI/12-118                 ...vkayl-----ISFIKFVSPNDAGSTGGHQAGLYIPK..N.S.F.S..LI..FE-FPGVKGIN..KERFANIIWFDGTISICCFK--YYGY----.........GTRNEYRITRLGKEF----------------------.....----------------.----------..-------------legqlvvivkksenhylgfil...........
G9RPY3_9FIRM/12-137                 .....alq---GTKVFCKFLSANDTGLTGGHQAGIYISK..P.S.I.P..IL..FDV-PGTKGQN..MEKWVKIRWMDGNETDS--RFIYYGQ----.........GTRNEYRITNFGRGFPYLR-PDFTGALFVFVQNSSED.....-----YQAFVLNTED-.----------..-------------einqfldaf.......................
A0A100YQX9_9FIRM/14-134             .....vnk---GKRAYCKFLSANDTGLTGGHQAGIYIAK..N.A.V.S..IL..FDTPCV-RGEN..KKKNIQIKWQDDFTTESVIT--YYGQ----.........GSRNEYRITKFGRGFELLNH-EHTGDLFVLVQWDTQD.....----------------.----------..-------------ysayelsqeddina..................
J0N5F7_9CLOT/12-136                 ....alqg----QKVFCKFLSANDTGVTGAHQAGIYISK..P.S.I.P..IL..FDEPGQ-KGQN..KEKWVKVRWQSDF--ETETRFIYYGQ----.........GTRNEYRITNFGRGFPYL-KPEYTGALFVLVMDNEEY.....----------------.----------..-------------yqgfvlntedeinqflds..............
C5BFF1_EDWI9/13-166                 ......tg---NAYVYIKRLSANDTGATGAHQVGTYMQH..S.A.A.E..YL..FPSINKTDECN..PSLMITARTSSHSYPENQVRVIYYNNKFFG.........KTRNERRITRWGGG-SPLQDTENTGALALLVFDSSLGg...kSDCQSVDVWVCRDADE.EDIVEASIGE..ILPGDLIFGLADE................................
A0A0J9B3I8_9BACT/12-165             .....asg---EFFLFIKRLSANDTGATGSHQVGIYIPA..E.I.V.A..ML..FPSISHTRSEN..PDTYLTATTSSHERTERKVRAIYYNGKFFG.........KTRNEKRITRWGGD-SPLQDPENTGALSILAFSKSES....nIDAQSVDVWVCASAAD.EDIVESVTGP..IIPGIFYAGHG--ne..............................
A8G987_SERP5/12-169                 .......s-SDNWYIHIKRLSANDTGASGGHQSGVYLPN..N.S.A.N..FL..FPSINRIDEEN..PSVGLTAKIISHEVNDSQVRAVYYNSKLRNl......npKGRNETRITCWGGQKSPVQNQNNTGAIAIFAFYTPEN....lKDCGLVEAWVCCTVEE.EDLLEAIIGE..VLPGTARSGPSA-q...............................
A0A142WRW3_9PLAN/7-117              ....kair---------KELSRNDTGETGGHQAGILVPR..EpT.V.L..RF..FPSLDA-KEYN..PRHSLVFR--DEVGEKWTFSFIYYNNKLFG.........GTRNEYRLTCM--------------------------.....----------------.----------..-------------tpfirshnlragdtlilsrdeenrfnitf...
Q9JZ51_NEIMB/26-167                 ........ANKSIAVYCRYIRPNDVGTTGSHQSGFYIQK..H.F.S.D..DL..FDVVCQ-KGTN..KTISIKINWQDGSVTNSNFK--YYGQ----.........GTRNEARITGFGKNFEFLSD-KYSGSLLVLCRACYKD.....---LLFHAFVL--SSD.EDI-EIFIAEtnILPGSLYLPKKQE................................
A0A0M4M5M9_9SPHN/1-118              .....mss-----QTYEKPLTANDTGETGGHQAGIHIPK..S.Q.T.DliAL..LPFLDP-AQKN..PDAWLEMTDDTG--VTWRFRYIYYNNRLHDd.......gGTRDEYRITHMTKFFRAVGA-----------------.....----------------.----------..-------------tegdvvvltgspgsltysvsv...........
X7F2M9_9RHOB/1-97                   .....mkk-------FLKTLSANDVGSTGAHMGGILIPK..G.D.A.E..LLafLPRLDP-KEYN..PDEWIQCVTPDGR--ELRLRYVYYNNRFHKp.......kGTRNEYRITHL--------------------------.....----------------.----------..-------------tkflrmegake.....................
N9W5I5_9SPHN/2-91                   ...tarti--------SKTLSANDTGDTGGHQAGILVPK..D.ReI.L..SF..FPSLDP-DEQN..PRCLLNFVDESGH--FWEFAFIYYNNRLFG.........GTRNEYRLTRMT-------------------------.....----------------.----------..-------------kyire...........................
A0A142WTD2_9PLAN/12-173             ......sg--PHIVWYVKRLAANDTLANESHQAGPYIPK..E.F.F.L..GV..FPSLNRPRDKN..PDKKVELTIDSHC-DARPVRAVWYNNKTSEpdapgakkkSKRDECRLTRFGGARSALLDPESTGSLAVFAFYRGET.....GESEVCHVWVCDTEVE.ADLVEDRVGP..VEPGKLTVWTVD-e...............................
A8AM36_CITK8/13-166                 .......s-TSDTYMFIKRLSANDTGATGGHQVGIYIPS..G.I.V.E..HL..FPSINHTRDLN..PSVMLNAHTSSHNCPDSEARAIYYNGRFFG.........KTRNEKRITRWGGGKNPLQDPENTGALALLAFDHHQG.....SDSQFVDIWVCHNAEE.EDIVESSLGE..IVPGSLVYGPANE................................
S6GR81_9GAMM/3-136                  .....esn--------AKLLTKNDTGETGGHQGGICVPRsnH.A.L.L..SF..FPELES-KKFN..PDTWLYCTD--PDGQEWKMRYVYYNGKIFSp......qqSTRNEYRITYMTGFFRKWEA--TAGDSVVFKATGQEN.....----------------.----------..-------------qyqifiekdakdlstedlapnpkv........
A5FU96_ACICJ/14-166                 ......gv--PGAVWFAKRLAANDTLATGAHGAGPYIPK..E.F.L.F..SV..FPDLNHPEEEN..PDCWFDLYIDSHA-DRRRIRAIWYNNRLRG.........GTRNEARLTNFGGGRSALLDPDSTGALAVFAFLPHGP.....GRQMECHVWVCDQGAE.ADLLEERIGP..VEPKAPVVWQPG-e...............................
D5QBY0_KOMHA/6-115                  ...fssai--------FKILSKNDSGMGAGHQAGFLIPT..E.L.R.-..SF..FPPLPEATIENpaPSILIDAILISDQTQPVRVITRWQAQTWYN.........QRSPETRLTG---------------------------.....----------------.----------..-------------eleiirkyscegdllliekseedi........
R6ETE5_9FIRM/14-148                 ....lnsr-----KAYCKFLSANDTGLTGGHQAGIYIAK..P.S.V.P..IL..FDEPG-IKGEN..KEKWVKVKWQDDI--ETDTRFIYYGQ----.........GTRNEYRITNFGRGFPF-LRPEYTGALFVFAKCS-DE.....----YYQAYILN--SE.DDI-------..-------------dqfldafgigptetnrl...............
E7GQT1_CLOSY/14-144                 .....lns----IQGFCKFLSANDTGATGGHQSGILISK..S.A.V.E..ML..FTKQQLDQEGI..PKRTVKIEWQDDLVTESRFT--YYES----.........--KNELRVTRFGRGF-PFLHPDQTGALFVFTKQSEDD.....Y---------------.----------..-------------sgyfleteeeieeflnafgisptet.......
A0A0K9GCN6_9BACI/16-155             ..akrygr------FYCKFITANDVGLTNAHQEGLHIAK..G.A.W.H..IF..FDEAGV-KGEN..KHKFVKIHIDGYYP--FDSRVIYYGR----.........GTRNEYRITRFWAY-SPFNKDEQVGNLIVFLPMSNVD.....-----FKVYILDTESEiEDFTETFLLN..LMH----------nnavyddg........................
A0A098T281_9PSED/1-98               ....mssi--------IKKLSANDIGYTGGHQAGILIPK..Q.EeI.L..AF..FPSLNR-TEKN..PRIQLTVREKNSE-TRWDFNLIYYNNKLFG.........GTRNEYRLTGM--------------------------.....----------------.----------..-------------trfcraadlqpdde..................
B3EB37_GEOLS/3-105                  ...ysaqi--------TKILSANDVGETGGHQAGILVPK..D.L.EiL..SF..FPSLNS-KEKN..PRVTLVFREGDG-ITRWDFNFIYYNNRFFG.........GTRNEYRLTCM--------------------------.....----------------.----------..-------------tqylrarnakvgdhvvls..............
A0A011U286_9RHIZ/14-168             ......tg--PSIVWYVKRLSGNDTLANGSHQAGPYIPR..S.F.L.F..DI..FPAINRTDIKN..PDLRFDVYIDSHA-DHRTARAIYYNNKFHEn......pkGGRNEARITGFGGGSSALLDPESTGALTVFAFVLDDT.....GAARECHVWVCRHETE.EDLVEDRIGP..VEPGKWAIWS---pd..............................
C4ZAA8_AGARV/13-138                 ....tvas----ELAFCKFLSANDTGATGGHQGGVLVSV..S.A.S.R..ML..FVEILP-DNDI..LKRDVKITWQGDLVTESTFT--YYSS----.........--KKELRITKFGRDFDII-NPDRTGSLFVLTKQSWDD.....-----YSVFIMD----.----------..-------------tedeieeflstfgi..................
A5P8H9_9SPHN/2-118                  .....gsq------TYEKPLTANDTGETGGHQAGIHIPK..S.Q.T.DliAL..LPFLDP-AQKN..PDAWLEMTDDAG--VTWRFRYIYYNNRLHDe.......gGTRDEYRITHMTKFFRAVGA-----------------.....----------------.----------..-------------tegdvlvltgspgsltysvsv...........
A0A0E9N2X2_9BACT/12-102             .....vka---NKISFFKFVSANDAGTTGGHQLGIYIPK..K.S.F.P..LL..FDQPGK-KGQN..MERFVEINWFDGTVSNACFK--YYGS----.........GTRNEYRITRIGINF----------------------.....----------------.----------..-------------tenel...........................
U2UYE2_9FIRM/14-133                 ...trqae-----SAFCKFLSANDSGETGGHQVGILISR..S.A.G.R..MF..FCERELRDNHI..LKKPVRVKWQDDFFTDSCLT--WYAS----.........--KKELRLTRFGRSFSLLQA-KYTGALFVLAKESDVD.....----------------.----------..-------------yaaflfdtedaiqq..................
A0A0M4D460_9DELT/15-167             ......gl---DCVWFVKRLSANDTLANETHQAGPYIPR..E.F.L.F..RV..FPEINRPDVEN..PDCRFVLSIDSHM-DRRIVRAIWYNKKLHG........tGTRNEARITGFGGRGSALLDPENTGALAIFAFLVDEQ.....GAASKCRVWVCRTEIE.ESLVEDRIGP..IDPGQSRIWAP--nl..............................
A0A0W0YKK4_9GAMM/2-113              nprtnaie---------KILSRNDTGETGGHQAGILIPK..N.Q.EiL..SF..FPSFDS-NEKN..PRFLI--TFKDHLGEQWSFSFIYYNSKFFG.........GTRNEYRLTSMTR------------------------.....----------------.----------..-------------ymnaynlksgdtltlsrnfdgfyy........
R7B2S4_9CLOT/15-146                 ..nsekgl--------CKFLSANDTGATGGHQSGILISK..S.A.V.E..MM..FSKQELEQAGI..PKRTVKVRWQDDFETESCFT--YYES----.........--KNELRITRFGRGF-PFLKPEQTGALFVFTQQTDFD.....----YCGYF-------.----------..-------------letdeeieefldtfgisptetns.........
A0A0G3UZF9_9ACTN/30-126             .gqvkris---------KILSRNDLGLTGSHQAGITVPR..N.P.E.F.lVI..FPKLDP-LIKN..PEAKVWVIAEEIE-YAGHLRFIYYNGKLLG........eGTRNEYRLTGV--------------------------.....----------------.----------..-------------tqllrglqam......................
R5GVJ7_9BACT/12-144                 ...vrsar-----LSFCRFITANDTGDTGAHQAGFYIPK..C.A.A.R..LL..FETPGQ-KGEN..KSRTVHICWQNDFTTESR--FIYYGR----.........GTRNEYRITRFGRNFPFFQE-SATGDLLIVAQESEDD.....-----YAAFVL--SSD.QDI-EDFLA-..-------------hfnldigsl.......................
A3X5U6_9RHOB/2-97                   ....ssek-------FRKRLSANDVGTTGGHQGGVLIPK..G.E.K.E..LLamLPALDP-EVKN..PDAWIECTDE--TGHTLKFRFVYYNNRLHDp.......gGTRNEYRITHM--------------------------.....----------------.----------..-------------tswfrdvga.......................
A0A085H7C2_9ENTR/27-180             .....agg---NYLVYIKRLSANDTGATGGHQVGLYIPS..G.I.V.E..KL..FPSINHTREMN..PSVFLTAHVSSHDCPDSEARAIYYNSRHFG.........KTRNEKRITRWGRG-SPLQDPENTGALTLLAFRLDEQ....gGDCKTVNIWVCASPDE.EDVIETAIGE..VIPGTLISGP---awq.............................
H2ISN5_RAHAC/12-169                 ........GNPEWVIYMKRLSANDTGATGGHQVGIYIPK..I.T.R.D..TL..FPSINRVDCDN..PSIPLSAKIVSHDIEEQTVNAIYYNSKLAKq......qkKGRNESRITSWGGKKSPIQDPENTGSLLILAFKKQTE....lADCMYLEAWICRSIEE.EDLLETITGE..ILPGISVFN----sgds............................
A9MS72_SALAR/13-166                 .......s-TSDTYMFIKRLSANDTGATGGHQVGIYIPS..G.I.V.E..HL..FPSINHTRDLN..PSVTLNAHTSSHSCPDTEARAVYYNGRFFG.........KTRNEKRITRWGGGKNPLQNPENTGALALLAFDHRQG.....ADSQFVDIWVCHDAEE.EDIVESSLGE..IVPGSLVYGPANE................................
R5UXG0_9BACT/13-149                 .....kra----KIIFLKLITANDTGATGAHQAGFHLPK..N.S.W.R..LF..FDSPG-IKGYN..KDKYITIRWGSFS---TESRAIYYGK----.........GTRNEYRLTRFGLHFPYLQE-QNIGDILIIIRNFDDT.....----------------.----------..-------------yegfiifkenilsfwmesglsennlntitina
A0A062TW84_9RHOB/11-163             ......sg--PSFVWYIKRLSGNDTQLTGGHQAGPYVPR..D.L.A.F..HL..MPHFEDLTRKN..PRGVVELQMFPGGYTTSS-NIIYYNNKFHDn......hsSGRNETRLTGLGGRENPLLDPENTGALSVFAFKLGAP.....---VQCQVWICGQREE.EVFLEDILGP..VEPGESIVWDP--gn..............................
E2ZD29_9FIRM/15-79                  ...sggps-------YCKFLSANDSGETGGHQSGILISK..S.A.K.A..ML..WTD--------..------------------------------.........-------------------------------------.....----------------.----------..-------------demrenhilkkygrirwqedyvtdctf.....
#=GC seq_cons                       ......st......hahKhLSANDTGtTGGHQuGIaIPK..s.t.h....hl..Fsshst.ctpN..Pcthlphphpst..pctph+hlYYss.............uTRNEhRITpastt...h.t.p.sGsLhlhh.....................................................t...............................
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