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Database: Pfam
Entry: Endonuc-PvuII
LinkDB: Endonuc-PvuII
Original site: Endonuc-PvuII 
#=GF ID   Endonuc-PvuII
#=GF AC   PF09225.5
#=GF DE   Restriction endonuclease PvuII
#=GF AU   Sammut SJ
#=GF SE   pdb_3pvi
#=GF GA   25.00 25.00;
#=GF TC   118.70 118.40;
#=GF NC   18.60 18.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   9878366
#=GF RT   Asp34 of PvuII endonuclease is directly involved in DNA minor
#=GF RT   groove recognition and indirectly involved in catalysis. 
#=GF RA   Horton JR, Nastri HG, Riggs PD, Cheng X; 
#=GF RL   J Mol Biol. 1998;284:1491-1504.
#=GF RN   [2]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR015306;
#=GF DR   SCOP; 3pvi; fa;
#=GF CC   Members of this family are predominantly found in prokaryotic
#=GF CC   restriction endonuclease PvuII. They recognise the
#=GF CC   double-stranded DNA sequence 5'-CAGCTG-3' and cleave after G-3,
#=GF CC   resulting in specific double-stranded fragments with terminal
#=GF CC   5'-phosphates [1].
#=GF SQ   14
#=GS H1NQS6_9SPHI/83-237  AC H1NQS6.1
#=GS Q8KT01_SALCE/6-160   AC Q8KT01.1
#=GS H1WFG5_9CYAN/4-143   AC H1WFG5.1
#=GS H9L4U0_SALPA/6-160   AC H9L4U0.1
#=GS B5W9S1_SPIMA/1-126   AC B5W9S1.1
#=GS E2NFK2_9BACE/1-133   AC E2NFK2.1
#=GS T2P2_PROHU/3-157     AC P23657.1
#=GS T2P2_PROHU/3-157     DR PDB; 1H56 B; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1EYU A; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 3KSK B; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1H56 A; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1F0O A; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 3KSK A; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1PVI B; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1F0O B; 4-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1PVU B; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 3PVI A; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1K0Z B; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1NI0 A; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 3PVI B; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1PVI A; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1EYU B; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 2PVI A; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1NI0 B; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 2PVI B; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1PVU A; 3-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1K0Z A; 5-157;
#=GS T2P2_PROHU/3-157     DR PDB; 1NI0 C; 3-157;
#=GS Q9EZ26_SALPT/6-160   AC Q9EZ26.1
#=GS D0KFJ3_PECWW/6-160   AC D0KFJ3.1
#=GS A1WNN0_VEREI/10-164  AC A1WNN0.1
#=GS B5BKT8_SALPK/6-160   AC B5BKT8.1
#=GS D3PMZ8_MEIRD/74-228  AC D3PMZ8.1
#=GS H0SKH6_9BRAD/1-72    AC H0SKH6.1
#=GS F7JJR5_9FIRM/9-162   AC F7JJR5.1
H1NQS6_9SPHI/83-237             neeli-----ALNMILPQIRRFQTLAEANGINDIFQDNGGKLLQVLLHTGLK.ILPGREGNDAVDDAGNEYELKSVNIRLT.KSFSTHHHMNPTIIKKYRKVDWIFAVYEGIELLEIYKLKPAHLEPYYVAWEKKWSADGDKDINNPKIPLKYVRLHGI---rll
Q8KT01_SALCE/6-160              .....HQDWSNLIALWPQVEEYQRLANKHGINDIFQDNGGKLLQVLLLLSLK.VLPGREGNDAVDVTGTEFELKSVNVELT.KSFSTHHHMNPTIIAKYRQVPWVFAIYSNITIRSVYLLMPDDLEVFYDKWERQWYERDGKDINNPKIPVKYVIEYGKLLW...
H1WFG5_9CYAN/4-143              .....HPDKAILDELFPYIQQYQALATKHGINDIFQDNGGKLLQVILVTGLQ.IIPGREGNDAKDADGNEFELKSVNIALT.KSFSTHHHINPRIIDKYRQVDWIFAVYRGINLLYIYKLTSSDLEYFYRKWEEKWYSKGGKDINNP---------------...
H9L4U0_SALPA/6-160              .....HQDWSNLIALWPQVEEHQRLANKHGINDIFQDNGGKLLQVLLLLSLK.VLPGREGNDAVDVTGTEFELKSVNVELT.KSFSTHHHMNPTIIAKYRQVPWVFAIYSNITIRSVYLLMPDDLEVFYDKWERQWYERDGKDINNPKIPVKYVIEYGKLLW...
B5W9S1_SPIMA/1-126              .....-----------------------------FQDNGGKLLQVILVTGLQ.IIPGREGNDAKDADGNEFELKSVNIALT.KSFSTHHHINPRIIDKYRQVDWIFAVYRGINLLYIYKLTSSDLEYFYRKWEEQWYSKGGKDINNPKIPLKYVIEHGQLLY...
E2NFK2_9BACE/1-133              ....m-----------------------YSINDVFQDNGGKLLQVLMITGLQnLDGSREGNDAVDSEGNEYELKSVNINLT.QSFSTNHHLNQHIIDKYRKVDWIFAVYKDIELVEIYKMTPEMIEPYYTKWETQ-YKTTGKDINNPKIPLKFVRENGIEIY...
T2P2_PROHU/3-157                .....HPDLNKLLELWPHIQEYQDLALKHGINDIFQDNGGKLLQVLLITGLT.VLPGREGNDAVDNAGQEYELKSINIDLT.KGFSTHHHMNPVIIAKYRQVPWIFAIYRGIAIEAIYRLEPKDLEFYYDKWERKWYSDGHKDINNPKIPVKYVMEHGTKIY...
#=GR T2P2_PROHU/3-157     SS    .....-THHHHHHHHHHHHHHHHHHHHHTT-S-TTSTTHHHHHHHHHHHT-E.E-TTTSSSEEE-TTS-EEEEEEEETTT-.SEEE--TTB-HHHHHHHTTS-EEEEEEETTEEEEEEEE-HHHHHHHHHHHHHHHHHTTS--BSS-EEEHHHHHHHSEEEE...
Q9EZ26_SALPT/6-160              .....HQDWSNLIALWPQVEEHQRLANKHGINDIFQDNGGKLLQVLLLLSLK.VLPGREGNDAVDVTGTEFELKSVNVELT.KSFSTHHHMNPTIIAKYRQVPWVFAIYSNITIRSVYLLMPDDLEVFYDKWERQWYERDGKDINNPKIPVKYVIEYGKLLW...
D0KFJ3_PECWW/6-160              .....HSDWQKLIDLWPQVEEYQRLANKHGVYDIFQDNGGKLLQVLLLLSLK.VLPGREGNDAQDITGTEFELKSVNVELT.KSFSTHHHMNPSIISKYRKVPWIFAIYSNITIRSVYLLMPIELEFFYEKWEGQWHERGGRDINNPKIPVKYVMEHGCLLW...
A1WNN0_VEREI/10-164             .....ETDKQKFERLFPCIREYQVLASKYKINDIFQDNGGKYLQLLMILGLT.TDGTREGNDAVDSFGNEYEIKTVNLELQ.HQFTTHHHMNPAIIAKYRKVDWYFAAFKNIELQVIYRLKPDHMESFYARWEKKWHDDGGKDINNPKIPLAHVMEYGEIIW...
B5BKT8_SALPK/6-160              .....HQDWSNLIALWPQVEEHQRLANKHGINDIFQDNGGKLLQVLLLLSLK.VLPGREGNDAVDVTGTEFELKSVNVELT.KSFSTHHHMNPTIIAKYRQVPWVFAIYSNITIRSVYLLMPDDLEVFYDKWERQWYERDGKDINNPKIPVKYVIEYGKLLW...
D3PMZ8_MEIRD/74-228             ....t-TDIAILEALFPYIRRYQILASRYGIADIFQDNGGKLLEILIRTGLK.IVPGREGNDAVDEQGQEYEIKSVNVELT.RSFSTHHHLNPSILDKYRRVRWIFAVYRNIELQEIYCLEPQQLERFFSDWERKWRAQGGKDINNPKIPLRYVQREGRLIY...
H0SKH6_9BRAD/1-72               .....-----------------------------------------------.----------------------------.--------MNPTIIAKYRQVDWIFAIYRNIELQRVYKLSPKDLEPYFSKWEEKWRSDGGKDINNPKIPIKFVKEVGTLVY...
F7JJR5_9FIRM/9-162              ...ra--EIAKIEQLWRNLNELDQMAHAYGISDIFQDNGAKVLQQLIYLNMS.ILPGREGNDCISTSGTEWEMKSINLETSaSGFSTNHHTTHDIIAKYRQVPWTFAIYYGINLAEMYVMTPEMLEPLYQHWEAKLQTMT--HLNNPKIPVKYVREHGIKVF...
#=GC SS_cons                    .....-THHHHHHHHHHHHHHHHHHHHHTT-S-TTSTTHHHHHHHHHHHT-E.E-TTTSSSEEE-TTS-EEEEEEEETTT-.SEEE--TTB-HHHHHHHTTS-EEEEEEETTEEEEEEEE-HHHHHHHHHHHHHHHHHTTS--BSS-EEEHHHHHHHSEEEE...
#=GC seq_cons                   .......DhttL.tLaPplpcaQtLAp+aGINDIFQDNGGKLLQVLLlhuLp.llPGREGNDAVDssGsEaELKSVNl-LT.KSFSTHHHMNPsIIuKYRQVsWlFAlYpsIslpplYhLpPc-LEsFYsKWEcpWapcsGKDINNPKIPlKYVhEaGplla...
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