GenomeNet

Database: Pfam
Entry: Endonuc-PvuII
LinkDB: Endonuc-PvuII
Original site: Endonuc-PvuII 
#=GF ID   Endonuc-PvuII
#=GF AC   PF09225.9
#=GF DE   Restriction endonuclease PvuII
#=GF AU   Sammut SJ
#=GF SE   pdb_3pvi
#=GF GA   25.00 25.00;
#=GF TC   27.30 153.40;
#=GF NC   21.50 21.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   9878366
#=GF RT   Asp34 of PvuII endonuclease is directly involved in DNA minor
#=GF RT   groove recognition and indirectly involved in catalysis. 
#=GF RA   Horton JR, Nastri HG, Riggs PD, Cheng X; 
#=GF RL   J Mol Biol. 1998;284:1491-1504.
#=GF RN   [2]
#=GF RM   22638584
#=GF RT   Sequence, structure and functional diversity of PD-(D/E)XK
#=GF RT   phosphodiesterase superfamily.
#=GF RA   Steczkiewicz K, Muszewska A, Knizewski L, Rychlewski L, Ginalski
#=GF RA   K;
#=GF RL   Nucleic Acids Res. 2012;40:7016-7045.
#=GF DR   INTERPRO; IPR015306;
#=GF DR   SCOP; 3pvi; fa;
#=GF CC   Members of this family are predominantly found in prokaryotic
#=GF CC   restriction endonuclease PvuII. They recognise the
#=GF CC   double-stranded DNA sequence 5'-CAGCTG-3' and cleave after G-3,
#=GF CC   resulting in specific double-stranded fragments with terminal
#=GF CC   5'-phosphates [1].
#=GF SQ   11
#=GS W0F4T8_9BACT/1-129       AC W0F4T8.1
#=GS A0A133ZNP7_9BACL/10-162  AC A0A133ZNP7.1
#=GS A0A090AJ56_9GAMM/5-158   AC A0A090AJ56.1
#=GS D3PMZ8_MEIRD/75-228      AC D3PMZ8.1
#=GS K9XGE0_9CHRO/113-266     AC K9XGE0.1
#=GS K7VYC2_9NOST/113-266     AC K7VYC2.1
#=GS A1WNN0_VEREI/11-164      AC A1WNN0.1
#=GS A0A139SV20_9GAMM/7-160   AC A0A139SV20.1
#=GS A0A060USX6_9PROT/7-160   AC A0A060USX6.1
#=GS K9VCS8_9CYAN/109-263     AC K9VCS8.1
#=GS A0A150YBK3_9FIRM/10-168  AC A0A150YBK3.1
W0F4T8_9BACT/1-129                  .....------------------------MNDIFQDNGGKLLQVLLHTGLKILPGREGNDAVDDAGNEYELKSVNIRLTKS..FSTHHHMNPTIIKKYRKVD.WIFAVYEGIELLEIYKLKPAHLEPYYVAWEKKWSAD.....GDKDINNPKIPLKYVRLHG----irl
A0A133ZNP7_9BACL/10-162             ...ne--IAKINRLWANLTELNKLAKTYGIPDIFQDNGAKVLQQLIYLNMSILPGREGNDCISASGTEWEMKSINLETSAS.gFSTNHHTTHYIIAKYRQVP.WTFAIYHGITLTEMYVMTPSMLEPLYQHWEEKLQ--.....TMAHLNNPKIPVKYVRENGIKV-f..
A0A090AJ56_9GAMM/5-158              ....p-DKNKLDELFPCIREYQELALKHGIQDIFQDNGGKLLQVILTTSLKVLPGREGNDAIDEFGNEYELKSVNILLTKS..FSTHHHLNPTIIRKYREVN.WVFSVYEGIELKEIYVLIPKQLEPFYQKWENKWYKE.....GNKDINNPKIPLSYVRKNGYLIF...
D3PMZ8_MEIRD/75-228                 .....TDIAILEALFPYIRRYQILASRYGIADIFQDNGGKLLEILIRTGLKIVPGREGNDAVDEQGQEYEIKSVNVELTRS..FSTHHHLNPSILDKYRRVR.WIFAVYRNIELQEIYCLEPQQLERFFSDWERKWRAQ.....GGKDINNPKIPLRYVQREGRLIY...
K9XGE0_9CHRO/113-266                .....SDLERLQTALEAIQELQTLANEYGINDVFQDNGGKVLQVLILLGLRISPGCEGNDAIDAEGHKYELKTINKLLSRS..VTTHHHLNLDILAKYRAVKaWYIAVYEGIVLKAIYRVAPTSLESKFSYWESRIF-E.....GMKSINNPKIPLALIEKEGKLVY...
K7VYC2_9NOST/113-266                .....SDLERLQTALGAIQELQSLANEYGINDVFQDNGGKVLQVLILLGLRISPGREGNDAIDAEKNEYELKTINKLLSKS..VTTNHHLNLDILAKYRAVKaWYIAVYEGILLKAIYRVDPTSLETKFSYWESRIR-G.....GMESINNPKIPLSLIEKEGELVY...
A1WNN0_VEREI/11-164                 .....TDKQKFERLFPCIREYQVLASKYKINDIFQDNGGKYLQLLMILGLTTDGTREGNDAVDSFGNEYEIKTVNLELQHQ..FTTHHHMNPAIIAKYRKVD.WYFAAFKNIELQVIYRLKPDHMESFYARWEKKWHDD.....GGKDINNPKIPLAHVMEYGEIIW...
A0A139SV20_9GAMM/7-160              ....a-DYQRLLDIWPAIQDYQELAAKHGIDDIFQDNGGKLLQVLLLLNLDILPGREGNDAVDETGREYELKSVNIELTHG..FSTHHHMNPSIIEKYRKVP.WVFAVYRNIALQSVYLLEPEELNFYFKKWEEKWHAD.....GGKDINNPKIPIKYVMAHGKLVF...
A0A060USX6_9PROT/7-160              ....d-DYARLLEIWPSVQEYQALATKHGIDDIFQDNGGKLLQVLLLMGLKILPGREGNDAVDASGREYELKSVNIELTKG..FSTHHHMNPTIIAKYRQVP.WAFAIYRHIALQAVYLLEPSDLEFYFTKWEEKWHAD.....GEKDINNPKIPVVYVMKHGRLI-h..
K9VCS8_9CYAN/109-263                .....SDAKRLENAMKSIQELQNLASEYGIADIFQDNGGKTLQLLILLGLRISPGREGNDAIDAEGKEYELKTINIALNRSggVTTHHHLNEIILEKYRRVEaWYIGLYEGITLKEIYKLTPEMLEPKFKEWEEKVR-L.....RNEPLNNPKIPLKLVKK-GQLVY...
A0A150YBK3_9FIRM/10-168             dkidc-----FNDMWSKLDDIEELAKTYQIADIAQDNNLKLLQTLVLFDFDNQPGREGSDAIDRYGHAWELKTVNIDLTSS..FSTNHHTNLERINVFRQER.WLFSSYKGIILQEVYVVNPRHLETYFSKWEQSVKEKiaaniENAHLNNPKIPLKYVKEVGTKVY...
#=GC seq_cons                       ......Dht+LpphassIpEhQpLAscYGIsDIFQDNGGKlLQlLllhGL+I.PGREGNDAlDspGpEYELKoVNlcLo+S..FSTHHHhN.sIIsKYRpVc.WhFAlYcGItLppIYhLpPppLEsaFscWEcKh+tc.....GsKcINNPKIPLpYVccpGpLla...
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