GenomeNet

Database: Pfam
Entry: EspB
LinkDB: EspB
Original site: EspB 
#=GF ID   EspB
#=GF AC   PF05802.10
#=GF DE   Enterobacterial EspB protein
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_8424 (release 8.0)
#=GF GA   21.80 21.80;
#=GF TC   22.10 21.90;
#=GF NC   21.70 21.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12071694
#=GF RT   Expression and purification of the recombinant enteropathogenic
#=GF RT   Escherichia coli vaccine candidates BfpA and EspB. 
#=GF RA   Quintana Flores VM, Campos de Souza Fernandes RC, Sousa de
#=GF RA   Macedo Z, Medina-Acosta E; 
#=GF RL   Protein Expr Purif 2002;25:16-22.
#=GF RN   [2]
#=GF RM   12405637
#=GF RT   Comparison of an espB gene fecal polymerase chain reaction assay
#=GF RT   with bacteriologic isolation for detection of Citrobacter
#=GF RT   rodentium infection in mice. 
#=GF RA   McKeel R, Douris N, Foley PL, Feldman SH; 
#=GF RL   Comp Med 2002;52:439-444.
#=GF DR   INTERPRO; IPR008611;
#=GF CC   EspB is a type-III-secreted pore-forming protein of
#=GF CC   enteropathogenic Escherichia coli (EPEC) which is essential for
#=GF CC   EPEC pathogenesis [1]. EspB is also found in Citrobacter
#=GF CC   rodentium [2].
#=GF SQ   10
#=GS A9MEL7_SALAR/10-166       AC A9MEL7.1
#=GS W8VBG8_YEREN/2-143        AC W8VBG8.1
#=GS D2TKE1_CITRI/1-321        AC D2TKE1.1
#=GS A0A098YCZ4_9ACTN/151-300  AC A0A098YCZ4.1
#=GS A0A0T7RND9_SALET/4-189    AC A0A0T7RND9.1
#=GS A0A0J1CL90_9BURK/2-201    AC A0A0J1CL90.1
#=GS C5B9R0_EDWI9/1-191        AC C5B9R0.1
#=GS A0A097QK35_9VIBR/1-194    AC A0A097QK35.1
#=GS N9TYN4_9GAMM/1-194        AC N9TYN4.1
#=GS E3BEJ8_9VIBR/2-150        AC E3BEJ8.1
A9MEL7_SALAR/10-166                  .............................fdkiwet------------------------------------------.-------LIELAKKLRNIMRAY---NVVKQQLSWELQVNAFNTQLKTIDQ....T.YKA...SILNGVGS..ICSGMLtigfGVTGG....E.....A...GV-MFGQGAGHIAAG...GF.SlggsAA........QRQSDqtsTIAE....LQQKGAQSYSKTLTEIMDKAADIMQQIMGMGTS-------------------------------....-----------------------------------------------------------------------------------------------------------lvdvlahilqslt.........................................................................
W8VBG8_YEREN/2-143                   .....................nmsvnhqitlpeqsk--------------------------IVTEKESESTGNYTENfISDLSNIIFKMNLLFKKMRDLLNKYNQKQQKLGWDIQVSSMSNKREAIDK....T.ASG...AIASGVCS..ILSGLVs.gaGAAAS....F.....K...FGDIATHGGSALGQL...G-.-....--........-----...----....----------------------------------------------------------------....-----------------------------------------------------------------------------------------------------------agsgklvegdmarnad......................................................................
D2TKE1_CITRI/1-321                   ....................................MNTIDYNNAAIAVNPVVSSTTDSASSTTTLTSSSSSSLLTAG.KVDISKLLLEVQKLMREMVTTLQDYLQRQLAQSYNIQQAIFQSQNKAIEE....K.KAG...ATAALIGG..AISSVL....GILGS....F.....A...AINSATKGASDVVQK...AT.S....AS........AKSVN...TASE....VSTKALVKASESIADAADETVGTLQQGIAAATKAANRTSGIADDVTTSAQKASQVAEEAADAAQdltrKANLLSRFTAAAGRISGSTAFVVVTSLAEGTKTLPTTISESVKSNHDINEQRAKSVENLQASNLETYKQDVRRSQDDIASRLRDMTATARDLNDLINRMGQSARLAG......................................................................................
A0A098YCZ4_9ACTN/151-300             ....................avedtvedvleetget------------------------------------------.--------------------------------------------------....-.---...--------..------....-----....-.....-...-IGKASDEVTSVAQK...AK.S....RT........DKAVD...AVED....TVEDVLAETGETIGKASDEVTSVAQKAKSRTDKAVDAAQQETQEVAESAKRS---ARDTAAPAK....KAPA---KKAAAKRTTKATPATVAPVMSEGT-TLPDPLAVPAKST--------------------------------------------------------------dats..................................................................................
A0A0T7RND9_SALET/4-189               snvalvlpapslltpsstpspsgegmgtesmlllfd------------------------------------------.--DIWMKLMELAKKLRD---IMRSYNVEKQRLSWELQVNVLQTQMKTIDQ....AfKASmitAGGAMLSG..VLTIGL....GAVGG....E.....TgliAGQAVGHTAGGVMGLgagVA.Q....RQ........SDQDK...AIAD....LQQNGAQSYNKSLTDIMEKATEIMQQIIG-----------------------------------....-----------------------------------------------------------------------------------------------------------vgsslvtvlaei..........................................................................
A0A0J1CL90_9BURK/2-201               ...........sqninsvtpastppgradssgavas---------------------------------------DDQ.PFSISTLMIEVTKLFQELRDQGQEFYVQSLQRQFSIQMEELKLKQDSIDD....T.K--...-TSALLGG..SFEIAA....GGLGV....M.....A...GAGSGA---AGLALK...NG.-....--........-----...----....----------------------------------------------------------------....-----------------------------------------------------------------------------------------------------------mgveagmqagnvlgrmtdgtgkvaaaysaadaqtstvlgefagknaeqykqgmdqamariqdlrekalqacaaykdlydrnasaik
C5B9R0_EDWI9/1-191                   ..mntidngsqgvngitspdnqgyisgdrdnnaigq------------------------------------------.---LNELMVQLGELFGKLRDVLRQYQQAQQSNAFKMQKTAFETRVDSIDKdfqaK.QAQ...AVAQIVGG..IAQTVG....GGFGE....HghtisT...GLNNMTQGIVGVGYA...NDlT....RQ........SQEEQ...ALSDy.qhGMADQLLKRAEETKEKALKVSGDLREILATLTQAHEHLS-------------------------....-----------------------------------------------------------------------------------------------------------ssvr..................................................................................
A0A097QK35_9VIBR/1-194               ...............................msevq---------------VSNNAPVNAASSTSYDHDVSGSEAMDA.IAQLNELIVKLAEIFKKLRNVLQEYNQKQQLLGWDVQKASMDTKRDAI--....K.SAF...ESAAWSGGlqILSGVV....GMVGV....G.....-...ATSKFGEGATHLGQ-...--.-....AL........GKSVD...GAGS....MVSASITKDAE-----------------------------------------------------....-----------------------------------------------------------------------------------------------------------mekmdgefkamnaqnyaknvnelsdkarqiseqmrslvkelvelhgriasav..................................
N9TYN4_9GAMM/1-194                   .............mntidnstsavgslstltstpgd-------------------------------------QGGDA.IGQLNELMVQLGQLFGKLRDVLRQYQQTQQNNAFQMQKTSFNTRLDAIEKdfdaK.QSQ...AIAQIVGG..VAQGVF....GALSAksegL.....S...GIGGVGHGIDSIAQG...IA.G....VSfgnqasreAQEGQ...ALADyqhgLAEQQLKRADETL-DKALKVSSDLREILTTLTQAHERLS-------------------------....-----------------------------------------------------------------------------------------------------------ssvr..................................................................................
E3BEJ8_9VIBR/2-150                   ..ttvqtntptpvsapavnddltvktdhsisdcdgm----------------------------------------EA.IAQLNDLMIKLSEVMQKLRDVLQQYNQKQQELGWDIQKASMDTKKEAIS-....-.KA-...CESSILSG..VLQIGA....GIAGM....A.....G...AGFSKSTGLGEATTH...LG.K....GA........GDSLS...GIG-....----------------------------------------------------------------....-----------------------------------------------------------------------------------------------------------tvvsaemtknaei.........................................................................
#=GC seq_cons                        ....................s.t.hstp..pts.sp........................................tt...plspLhlcLuclhpclRclLppYpQpQQphuaclQhsuhpT+h-uI-p....p.put...uhuuhlGG..lhpssh....GshGs....h.....s...ussssucGsuulupt...ss.p....tt........ucpsp...ulu-....h.ppth.phscph.ch..csst.hpphhs..................................................................................................................................................susp....ht............................................................................
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