GenomeNet

Database: Pfam
Entry: EspB
LinkDB: EspB
Original site: EspB 
#=GF ID   EspB
#=GF AC   PF05802.9
#=GF DE   Enterobacterial EspB protein
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_8424 (release 8.0)
#=GF GA   21.80 21.80;
#=GF TC   22.10 21.90;
#=GF NC   21.70 21.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   12071694
#=GF RT   Expression and purification of the recombinant enteropathogenic
#=GF RT   Escherichia coli vaccine candidates BfpA and EspB. 
#=GF RA   Quintana Flores VM, Campos de Souza Fernandes RC, Sousa de
#=GF RA   Macedo Z, Medina-Acosta E; 
#=GF RL   Protein Expr Purif 2002;25:16-22.
#=GF RN   [2]
#=GF RM   12405637
#=GF RT   Comparison of an espB gene fecal polymerase chain reaction assay
#=GF RT   with bacteriologic isolation for detection of Citrobacter
#=GF RT   rodentium infection in mice. 
#=GF RA   McKeel R, Douris N, Foley PL, Feldman SH; 
#=GF RL   Comp Med 2002;52:439-444.
#=GF DR   INTERPRO; IPR008611;
#=GF CC   EspB is a type-III-secreted pore-forming protein of
#=GF CC   enteropathogenic Escherichia coli (EPEC) which is essential for
#=GF CC   EPEC pathogenesis [1]. EspB is also found in Citrobacter
#=GF CC   rodentium [2].
#=GF SQ   6
#=GS D2TKE1_CITRI/1-321      AC D2TKE1.1
#=GS A9MEL7_SALAR/10-166     AC A9MEL7.1
#=GS C5B9R0_EDWI9/1-191      AC C5B9R0.1
#=GS A0A097QK35_9VIBR/1-194  AC A0A097QK35.1
#=GS E3BEJ8_9VIBR/2-150      AC E3BEJ8.1
#=GS W8VBG8_YEREN/2-143      AC W8VBG8.1
D2TKE1_CITRI/1-321                 ..................................MNTIDYNNAAIAVNPVVSSTTDSASSTTTLTSSSSSSLLTAG.KVDISKLLLEVQKLMREMVTTLQDYLQRQLAQSYNIQQAIFQSQNKAIEE....KKAGATAALIGG..AISSVL....GILGSF.....AAINSATKGASDVVQKAT.S....ASAKSVN...TASE...VSTKALVKASESIADAADETVGTLQQGIAAATKAANRTSGIADDVTTSAQKASQVAEEAADAAQdltrKANLLSRFTAAAGRISGSTAFVVVTSLAEGTKTLPTTISESVKSNHDINEQRAKSVENLQASNLETYKQDVRRSQDDIASRLRDMTATARDLNDLINRMGQSARLAG....................................................
A9MEL7_SALAR/10-166                ...........................fdkiwet------------------------------------------.-------LIELAKKLRNIMRAY---NVVKQQLSWELQVNAFNTQLKTIDQ....TYKASILNGVGS..ICSGMLtigfGVTGGE.....AGV-MFGQGAGHIAAGGF.SlggsAAQRQSDqtsTIAE...LQQKGAQSYSKTLTEIMDKAADIMQQIMGMGTS-------------------------------....-----------------------------------------------------------------------------------------------------------lvdvlahilqslt.......................................
C5B9R0_EDWI9/1-191                 mntidngsqgvngitspdnqgyisgdrdnnaigq------------------------------------------.---LNELMVQLGELFGKLRDVLRQYQQAQQSNAFKMQKTAFETRVDSIDKdfqaKQAQAVAQIVGG..IAQTVG....GGFGEHghtisTGLNNMTQGIVGVGYANDlT....RQSQEEQ...ALSDyqhGMADQLLKRAEETKEKALKVSGDLREILATLTQAHEHLS-------------------------....-----------------------------------------------------------------------------------------------------------ssvr................................................
A0A097QK35_9VIBR/1-194             .............................msevq---------------VSNNAPVNAASSTSYDHDVSGSEAMDA.IAQLNELIVKLAEIFKKLRNVLQEYNQKQQLLGWDVQKASMDTKRDAI--....KSAFESAAWSGGlqILSGVV....GMVGVG.....-ATSKFGEGATHLGQ---.-....ALGKSVD...GAGS...MVSASITKDAE-----------------------------------------------------....-----------------------------------------------------------------------------------------------------------mekmdgefkamnaqnyaknvnelsdkarqiseqmrslvkelvelhgriasav
E3BEJ8_9VIBR/2-150                 ttvqtntptpvsapavnddltvktdhsisdcdgm----------------------------------------EA.IAQLNDLMIKLSEVMQKLRDVLQQYNQKQQELGWDIQKASMDTKKEAIS-....-KA-CESSILSG..VLQIGA....GIAGMA.....GAGFSKSTGLGEATTHLG.K....GAGDSLS...GIG-...----------------------------------------------------------------....-----------------------------------------------------------------------------------------------------------tvvsaemtknaei.......................................
W8VBG8_YEREN/2-143                 ...................nmsvnhqitlpeqsk--------------------------IVTEKESESTGNYTENfISDLSNIIFKMNLLFKKMRDLLNKYNQKQQKLGWDIQVSSMSNKREAIDK....TASGAIASGVCS..ILSGLVs.gaGAAASF.....KFGDIATHGGSALGQLG-.-....-------...----...----------------------------------------------------------------....-----------------------------------------------------------------------------------------------------------agsgklvegdmarnad....................................
#=GC seq_cons                      ..............................t.sp........................................ts.hspLscLllcLuclh+KlRclLppYNQ+QQpLuW-lQpuuhsT+p-AI-p....ppAtuhAuhlGG..IlSull....GhsGst.....sussphopGuuclupts..p....utucp.s...shup...h.ttth.p.uc....................................................................................................................................................................hssh....ht..h.......................................
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