GenomeNet

Database: Pfam
Entry: Exonuc_VIII
LinkDB: Exonuc_VIII
Original site: Exonuc_VIII 
#=GF ID   Exonuc_VIII
#=GF AC   PF06630.9
#=GF DE   Enterobacterial exodeoxyribonuclease VIII
#=GF AU   Moxon SJ
#=GF SE   Pfam-B_11449 (release 9.0)
#=GF GA   25.00 25.00;
#=GF TC   39.60 30.10;
#=GF NC   22.50 19.20;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   2199308
#=GF RT   Physical analysis of spontaneous and mutagen-induced mutants of
#=GF RT   Escherichia coli K-12 expressing DNA exonuclease VIII activity. 
#=GF RA   Mahajan SK, Chu CC, Willis DK, Templin A, Clark AJ; 
#=GF RL   Genetics 1990;125:261-273.
#=GF DR   INTERPRO; IPR010584;
#=GF CC   This family consists of several Enterobacterial
#=GF CC   exodeoxyribonuclease VIII proteins.
#=GF SQ   15
#=GS A6T894_KLEP7/2-194       AC A6T894.1
#=GS J1QP67_9ENTR/1-190       AC J1QP67.1
#=GS A0A089R5V5_PLUGE/3-181   AC A0A089R5V5.1
#=GS I6HH71_SHIFL/3-190       AC I6HH71.1
#=GS C5BBP6_EDWI9/2-105       AC C5BBP6.1
#=GS RECE_ECOLI/2-178         AC P15032.3
#=GS A0A0G4K1D3_9ENTR/40-111  AC A0A0G4K1D3.1
#=GS Q8XF26_SALTY/3-194       AC Q8XF26.1
#=GS I2B9H5_SHIBC/6-107       AC I2B9H5.1
#=GS J1QZ13_9ENTR/2-196       AC J1QZ13.1
#=GS G7LMX3_9ENTR/4-131       AC G7LMX3.1
#=GS I6H369_SHIFL/1-124       AC I6H369.1
#=GS A0A090TWC2_9ENTR/3-193   AC A0A090TWC2.1
#=GS A4WB56_ENT38/2-172       AC A4WB56.1
#=GS A8AHT0_CITK8/3-205       AC A8AHT0.1
A6T894_KLEP7/2-194                  .........................................ey-----FYLIKATQKSGKADAVIWRTN..KSEArAL..L.....QLDVD...LEDAGIe..tgRG...KDYQKPIRTDFPVFNDLPAEGLLDYSWCERYQL.G.DDGRTWALKPG-QAPADHh.iDNAGVSAEPV.SGelVdANTTGDAAQgETVETFGS.D-----EYQDDS..........SA..LFNVAELPFRAQLLAQYMAEERHVYHI..SMPHRQELSV.........LEMDTDNAAVQDL...........................
J1QP67_9ENTR/1-190                  .........................................me----FFYLIKATQKSGKPSAVVWFSA..KTEA.R-..A.....KLQVQ...VILEDNeiatgRG...HDYQLPVLTNFPVVDDLPAEEAIDFTWCDRYSL.T.DDGRTWLKITS----QAT...TDTQDT-EST.EG..A.VNEAADPVS.SPAETSPL.QTNTHSDVTEDD..........DEntLYPVVKLRLPQRIIAQY-LSDKMRHHV..TQSQRVEIGA.........MEMDSDNNHVQNL...........................
A0A089R5V5_PLUGE/3-181              .................................tyaylikaka------------KAANAKSFFCWFSAksDSRA.DR..Q.....ILDILedaEIETGR.....G-...ADHQLPIRTNWFVVDDLPEEGVLDDTWCDRYTL.A.DDGASWQKIVA--EPAPT...P-APEQEQ--.--..-.---EQEQEQ.EQEQPI--.--PSTPLSTSDE..........NL..TYNLALLPFRAQLLAQFLTEEKHASHI..SWPTKCQIAD.........LEMDTDNNYIQNL...........................
I6HH71_SHIFL/3-190                  ...........................................GTNPVFLVRRAKKQSGNKDAVLWCSD..DFEA.VN..A.....TLDYL...LIKTGA.....KL...KDYFKAVATNFPVVNELPPEGELSLTFCDFYHL.R.DDNMTWEQIPGITLPSSD...AAAEARQHIV.NG..V.DTNTGEILE.ESTGAV--.DSKSTG--NTST..........PA..LTVIATMPFRHRVLAQFIGDGKYLYHV..DAAQKIEIVG.........LEMDTDESYIQNL...........................
C5BBP6_EDWI9/2-105                  ......................................setfa------FLTKAKKKSGKPDMMFWCSA..TNERiAR..S.....KLSIA...LDAAGL.....DE...ADYFNPQRTHLPVVDDLPPEDVLSSDFCRHYQM.E.DNNWVRRQEPL---P---...----------.--..-.---------.--------.------------..........--..---------------------------..----------.........-------------paktappsgepq...............
RECE_ECOLI/2-178                    ...........................................STKPLFLLRKAKKSSGEPDVVLWASN..DFES.TC..A.....TLDYL...IVKSGK.....KL...SSYFKAVATNFPVVNDLPAEGEIDFTWSERYQL.S.KDSMTWELKPG-------...-AAPDNAH-Y.QG..N.TNVNGEDMT.EIEENM--.------------..........--..LLPISGQELPIRWLAQH-GSEKPVTHVsrDGLQALHIARaeelpavtaLAVSHKTSLLDPL...........................
A0A0G4K1D3_9ENTR/40-111             .....................................ietdrg--------------------------..----.--..-.....-----...------.....--...ADYQLPISADFPVFDDLPEEGVLDDTWCDRYEL.A.DDERTWRKILGTEQKST-...----------.--..-.---------.--------.------------..........--..---------------------------..----------.........-------------niqddhtstagaqpt............
Q8XF26_SALTY/3-194                  ...........................................GTNPVFLVRKAKKSSGQKDAVLWCSD..DFEA.AN..A.....TLDYL...LIKSGA.....KL...KDYFKAVATNFPVVNELPPEGELSLTFCDYYQL.A.KDNMTWTQIPGVTLPSSE...AAAAARQHIV.DG..V.DTETGEVLE.DHTENFGN.ESNSPAQATAPA..........PE..LTVVATMPLRHRVLAQYIGEGEYLYHV..DASQKKEILR.........LEMDTDNSYVQNL...........................
I2B9H5_SHIBC/6-107                  yyikakaksdakslfcwfsaksdsraereianiledadiatgr--------------------------..----.--..-.....-----...------.....-G...TDYQLPQRTGWHAVDDLPREGILDETWCERYTL.SaDDNMTWESIIT-------...----------.--..-.---------.--------.------------..........--..---------------------------..----------.........-------------dlppatgtdtvn...............
J1QZ13_9ENTR/2-196                  ......................................ntyaf-------LIKAKAKSDAKNLFCWLSA..KTDA.RAdrE.....ILN-I...LEDAGI.....EVgrgHNHQLPVRTNWFVVDDLPEEGALDETWCDRYEL.G.DDGLSWQKIVNIAAPAPApapAPAPAPENLNpDV..G.ETQPGTLYE.SAQPPVAG.DSD--ITPDDDA..........NT..EYPVSRLRLPQRIIAQY-LSDKFRHHV..TMSQRVEIGA.........MELDSDNSHVQNL...........................
G7LMX3_9ENTR/4-131                  ......................................fayli---------KAKAKADAKSLFCWFSA..KSES.RG..NreilnILEDA...EIETGR.....-G...ADYQLPVRTNLPVFDDLPEEGVLDDTWCDRYEL.A.DDGRTWQKIAA-GAPNSV...NIQD------.--..-.---------.--------.------------..........--..---------------------------..----------.........-------------dhastagtqptaapgdavggtitidqt
I6H369_SHIFL/1-124                  ...........................................--------------------------..----.--..-.....-----...------.....--...----------MPVVDDLPPEGVFDTEFCNRYEKgG.EDGITMVFIAS--SPSVQ...D----KPA-S.TD..N.TNVNGEDMT.EIEENM--.------------..........--..LLPVSGQELPIRWLAQH-GSEKPVTHVsrDELQALHIARdeelpavtaLAVSHKTSLLDPL...........................
A0A090TWC2_9ENTR/3-193              ...........................................GTNPVFLVRRAKKQSGNKDAVLWCSD..DFEA.VN..A.....TLDYL...LIKTGA.....KL...KNYFKAVATNFPVVNELPPEGELSLTFCDFYRL.R.DDNMTWEQIPGVTLPSSD...AAAEARQHIV.NG..V.DTSTGEIVD.QSQLDQSD.NNGLDVDEYDDE..........YT..RYPIVQMPFRKQLLSQF-TSDALRHHL..TQTEHKEIVG.........LEMDTDNGYVQNL...........................
A4WB56_ENT38/2-172                  .........................................ef-----FNLIKATQKSGKPDGIIWFSA..KTDS.RA..S....lLLDVA...LEDAGIe..tgRG...NDYNKPVRTDFPVFNDLPEEGVLDFGWCTRYEL.G.EDARTWYPKAK-------...-IANDKAE--.--..-.-NENSVTSA.ATDTNI--.EPPAPAVDT---..........--..TVPVENRNQGVRF-AIHLMNDKYQTHI..SKDQQVAASE.........LVLEEGNTYLHN-l..........................
A8AHT0_CITK8/3-205                  ...........................................GTNPVFLVRKAKKSSGQKDAVLWCSD..DLEA.AN..A.....TLDYL...LIKSGA.....KL...KDYFKAVATNFPVVNELPPEGELSLTFCDFYQL.G.SDNMTWAQIPGVTLPSSD...AAAEARQHIV.NG..V.DTETGEVLE.DHTEEVVDtETGEITQHEQPStedngdrpehPQ..LTVVATMPFRHRVLAQHIGDGEYLYHV..DEEQKKAILA.........LEMDTDNSYVQNL...........................
#=GC seq_cons                       ..................................................lhKApppSGp.shhhWhSs..c.Eu.tt..s.....hL-hh...l.csGh.....ch...pDY.hPVtTNFPVVsDLPsEGhLDhTWCDRYpL.u.DDshTWppIsu...Pust...s.A.sptp...ps..s..s.su-.hp.p.ptsh.............................hhslsth.h.hphlAQa.hptchhhHl..s..pphpIst.........Lth-pcsshlpsL...........................
//
DBGET integrated database retrieval system