GenomeNet

Database: Pfam
Entry: FBPase_3
LinkDB: FBPase_3
Original site: FBPase_3 
#=GF ID   FBPase_3
#=GF AC   PF01950.13
#=GF DE   Fructose-1,6-bisphosphatase
#=GF PI   DUF100; 
#=GF AU   Enright A, Ouzounis C, Bateman A, Mistry J
#=GF SE   Enright A
#=GF GA   25.00 25.00;
#=GF TC   41.70 27.20;
#=GF NC   19.20 17.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Fructose_1,6-bisphosphatase
#=GF RN   [1]
#=GF RM   15274916
#=GF RT   The first crystal structure of the novel class of
#=GF RT   fructose-1,6-bisphosphatase present in thermophilic archaea. 
#=GF RA   Nishimasu H, Fushinobu S, Shoun H, Wakagi T; 
#=GF RL   Structure (Camb) 2004;12:949-959.
#=GF DR   INTERPRO; IPR002803;
#=GF DR   SCOP; 1umg; fa;
#=GF CC   This is a family of bacterial and archaeal
#=GF CC   fructose-1,6-bisphosphatases (FBPases).  FBPase catalyses the
#=GF CC   hydrolysis of D-fructose-1,6-bisphosphate (FBP) to
#=GF CC   D-fructose-6-phosphate (F6P) and orthophosphate and is an
#=GF CC   essential regulatory enzyme in the glyconeogenic pathway.
#=GF SQ   117
#=GS A2BK38_HYPBU/6-366      AC A2BK38.1
#=GS A8MDX2_CALMQ/4-373      AC A8MDX2.1
#=GS F6BB66_METIK/5-364      AC F6BB66.1
#=GS F8ACB1_THEID/2-362      AC F8ACB1.1
#=GS E3GZ16_METFV/2-362      AC E3GZ16.1
#=GS Q3AD99_CARHZ/3-359      AC Q3AD99.1
#=GS T0N266_9EURY/2-366      AC T0N266.1
#=GS C9R9G3_AMMDK/3-360      AC C9R9G3.1
#=GS Q9HIB3_THEAC/2-366      AC Q9HIB3.1
#=GS Q9YD03_AERPE/6-366      AC Q9YD03.2
#=GS F8C4Z5_THEGP/2-362      AC F8C4Z5.1
#=GS D9Q2U6_ACIS3/7-366      AC D9Q2U6.1
#=GS Q8ZY51_PYRAE/2-372      AC Q8ZY51.1
#=GS O67659_AQUAE/2-362      AC O67659.1
#=GS A5UUY1_ROSS1/4-364      AC A5UUY1.1
#=GS F4BZ11_METCG/3-368      AC F4BZ11.1
#=GS M1E4F8_9FIRM/221-281    AC M1E4F8.1
#=GS A3DMZ2_STAMF/6-366      AC A3DMZ2.1
#=GS K0I7L4_NITGG/2-361      AC K0I7L4.1
#=GS K4LFM4_THEPS/4-361      AC K4LFM4.1
#=GS F2KSE7_ARCVS/4-369      AC F2KSE7.1
#=GS A9A3J9_NITMS/5-362      AC A9A3J9.1
#=GS Y299_METJA/8-367        AC Q57747.1
#=GS A2ST38_METLZ/2-115      AC A2ST38.1
#=GS Q83E23_COXBU/2-377      AC Q83E23.1
#=GS E6P8F5_9ARCH/2-370      AC E6P8F5.1
#=GS D7E6J1_METEZ/2-367      AC D7E6J1.1
#=GS B1I5L9_DESAP/4-361      AC B1I5L9.1
#=GS G7WRF4_METH6/3-367      AC G7WRF4.1
#=GS B0KD99_THEP3/3-360      AC B0KD99.1
#=GS D9S0X7_THEOJ/3-361      AC D9S0X7.1
#=GS H3ZMW0_THELN/6-372      AC H3ZMW0.1
#=GS B8GG85_METPE/6-298      AC B8GG85.1
#=GS A8A9E4_IGNH4/4-363      AC A8A9E4.1
#=GS D8PEU2_9BACT/8-368      AC D8PEU2.1
#=GS A4FCE3_SACEN/1-361      AC A4FCE3.1
#=GS Q5SJM8_THET8/2-363      AC Q5SJM8.1
#=GS D3DG54_HYDTT/2-362      AC D3DG54.1
#=GS Q3Z761_DEHM1/2-361      AC Q3Z761.1
#=GS Q2NGI0_METST/2-362      AC Q2NGI0.1
#=GS Q2RG86_MOOTA/4-361      AC Q2RG86.1
#=GS E8N0E8_ANATU/4-363      AC E8N0E8.1
#=GS A4YIZ5_METS5/2-362      AC A4YIZ5.1
#=GS T0M774_9EURY/1-223      AC T0M774.1
#=GS I0A1U2_FERFK/6-365      AC I0A1U2.1
#=GS C9RC35_AMMDK/4-361      AC C9RC35.1
#=GS D3RYX0_FERPA/3-368      AC D3RYX0.1
#=GS F2NM38_MARHT/2-364      AC F2NM38.1
#=GS A0A0A7LBV6_9EURY/5-378  AC A0A0A7LBV6.1
#=GS A1RWM6_THEPD/2-363      AC A1RWM6.1
#=GS Q4JAX4_SULAC/2-362      AC Q4JAX4.1
#=GS Q8NKR9_THEKO/6-372      AC Q8NKR9.1
#=GS Q2LW91_SYNAS/1-71       AC Q2LW91.1
#=GS A6UTE1_META3/5-364      AC A6UTE1.1
#=GS Q89RC1_BRADU/2-370      AC Q89RC1.1
#=GS B5IAB6_ACIB4/3-368      AC B5IAB6.1
#=GS D7DUP4_METV3/4-363      AC D7DUP4.1
#=GS F6CK08_DESK7/4-361      AC F6CK08.1
#=GS T0NH40_9EURY/2-137      AC T0NH40.1
#=GS F0LKH3_THEBM/6-372      AC F0LKH3.1
#=GS D5VRN5_METIM/5-364      AC D5VRN5.1
#=GS Q980K6_SULSO/2-362      AC Q980K6.1
#=GS L0ABT5_CALLD/8-367      AC L0ABT5.1
#=GS O28830_ARCFU/3-368      AC O28830.1
#=GS R9TA35_9EURY/4-377      AC R9TA35.1
#=GS E6SJ08_THEM7/2-364      AC E6SJ08.1
#=GS D3E166_METRM/2-361      AC D3E166.1
#=GS A0A075WS01_9BACT/2-362  AC A0A075WS01.1
#=GS B4U833_HYDS0/2-361      AC B4U833.1
#=GS A7I8R8_METB6/3-361      AC A7I8R8.1
#=GS A0A0A7UZW4_9ARCH/2-359  AC A0A0A7UZW4.1
#=GS T0LQP2_9EURY/2-366      AC T0LQP2.1
#=GS N0BIT8_9EURY/4-368      AC N0BIT8.1
#=GS U6EBE5_9EURY/2-362      AC U6EBE5.1
#=GS I3TD51_THEC1/4-364      AC I3TD51.1
#=GS D8K128_DEHLB/2-361      AC D8K128.1
#=GS O27721_METTH/2-362      AC O27721.1
#=GS D5U307_THEAM/4-364      AC D5U307.1
#=GS E0SPU6_IGNAA/6-366      AC E0SPU6.1
#=GS A2ST38_METLZ/134-223    AC A2ST38.1
#=GS Q8U359_PYRFU/6-372      AC Q8U359.1
#=GS Q8TWS8_METKA/8-371      AC Q8TWS8.1
#=GS G4RLD7_THETK/2-372      AC G4RLD7.1
#=GS A3CVU2_METMJ/3-361      AC A3CVU2.1
#=GS I4BZA2_ANAMD/2-363      AC I4BZA2.1
#=GS A0B8T5_METTP/3-368      AC A0B8T5.1
#=GS A5D3Q9_PELTS/4-361      AC A5D3Q9.1
#=GS M4YPD9_9EURY/4-377      AC M4YPD9.1
#=GS A9BGJ9_PETMO/3-368      AC A9BGJ9.1
#=GS G0ECP9_PYRF1/25-385     AC G0ECP9.1
#=GS D3SN22_THEAH/2-362      AC D3SN22.1
#=GS B1L6Y4_KORCO/3-363      AC B1L6Y4.1
#=GS Q8RCX0_CALS4/3-360      AC Q8RCX0.1
#=GS Q6M0F4_METMP/4-363      AC Q6M0F4.1
#=GS B2A2Q6_NATTJ/2-363      AC B2A2Q6.1
#=GS F2NK02_DESAR/4-363      AC F2NK02.1
#=GS M9SDA8_9EURY/4-376      AC M9SDA8.1
#=GS Q6L0W0_PICTO/2-366      AC Q6L0W0.1
#=GS F0TA10_METLA/2-362      AC F0TA10.1
#=GS F9VMT6_SULTO/2-362      AC F9VMT6.1
#=GS F9VMT6_SULTO/2-362      DR PDB; 3R1M A; 3-363;
#=GS F9VMT6_SULTO/2-362      DR PDB; 1UMG A; 3-363;
#=GS F4LWX0_TEPAE/4-362      AC F4LWX0.1
#=GS H5X3U9_9PSEU/1-361      AC H5X3U9.1
#=GS E1QTV0_VULDI/2-371      AC E1QTV0.1
#=GS D2RDW4_ARCPA/4-369      AC D2RDW4.1
#=GS A0RV30_CENSY/131-487    AC A0RV30.1
#=GS A0A086YTL3_9FIRM/4-361  AC A0A086YTL3.1
#=GS A0A060HR72_9ARCH/2-361  AC A0A060HR72.1
#=GS Q2LQY4_SYNAS/2-363      AC Q2LQY4.1
#=GS A0A0A7GK02_9EURY/1-363  AC A0A0A7GK02.1
#=GS T0LKG6_9EURY/2-366      AC T0LKG6.1
#=GS J1APM5_9EURY/1-260      AC J1APM5.1
#=GS R9SJ68_9EURY/2-361      AC R9SJ68.1
#=GS F4B800_ACIHW/5-365      AC F4B800.1
#=GS F6D4D1_METPW/2-362      AC F6D4D1.1
#=GS B8D642_DESK1/4-364      AC B8D642.1
#=GS T0NFL9_9EURY/2-366      AC T0NFL9.1
#=GS A5UKU2_METS3/2-361      AC A5UKU2.1
A2BK38_HYPBU/6-366                 ........RVTISVIKADIGSIAGHHKVHPDTIAAATRVLAEAKRKGTIIDFYVTHVGDDLQLIMTHRKGVDSPEIH.GLAWEAFKKAA.EVAKELGLYAAGQDLLSDAFSGNVRGLGPGVAEMEFVE......RPSEPIVVFMADKTEPGAFNLPLYRIFADPFNTAGLVIDPRMHDGFKFEVLDVLE.....GKYVVLNAPEELYDLLALIGTPSRYVIKRIYRK......RDNE.IAAVVSVERLNLIAGRYVGKDDPVAIVRAQSGFPAVGEILEPFS.FPH.LVAGWMRGSHWGPLMPVSLRDAKC..........TRFDGPPRIVALGFQVT.KGKLIG............P.VDLFDDPAFDEARRLAQQIADYMRRHGPFMPHRLGPEEMEYT.TLPQVLEKLKNRF-a............................
A8MDX2_CALMQ/4-373                 ........KTTVSVIKADIGGIPGHAWVHPKILEYASSRLREAVKSGLLIDYYVFNVGDDMSLLMTHTKGIDNPEIH.GLAWSVFKEATeNYAKKFKLYGAGQDLLKDSFSGNVRGLGPQVAEMEFEE......RPSEPLIIFAADKTEPGAYNLPMYKIFADPFNTAGLVIDPQMHGGFRFEIIDVYE.....GKVYLLDAPEHIYTILGLIGTPGRYIIRRVYRR......SDLT.QAAVVSVERLNLIAGRYVGKDDPVAIVRAQHGLPAVGEVLEAFA.LPH.LVEGWMRGSHTGPLMPGKFVSIDPankiamgpkmTRFDGPPKVGALGFQLH.EGYLEG............P.VDMFDDPAFDFSRQIAAFITDYIRRMGPIMPHRLPPEEMEYT.TLPQILSTLK----pi...........................
F6BB66_METIK/5-364                 ........KITVSVIKADVGGLCGHTLAPEDLLEACEGVLEEAVDE-LIIDYYVTRCGDDVDLIMTHKMGVDNEKIH.KLAWNAFEEAT.KIAKELKLYGAGQDLLAECFSGNVRGLGPGCAEMEFVE......RPSEPIVVFCCDKTDPAAFNLPLYKIFADPFNTAGLVFDPSMTSGFAFEVHDVIG.....SKKVILNTPEETYSLLALIGDVERYAIKRVYRR......RDNE.IAAVVSTEKLNYIAGEYVGKDDPVAVVRAQSGFPAVGEILEPFA.NPH.FVAGWMRGSHWGPLMPVGEEDATP..........SRFDGPARIMALGFQLA.DGMLIG............P.NDLFADKGFDKAREKALEMADIIRRMGPFQPHRLPSGMMEYT.TVPKVLEKLKDRFE.............................
F8ACB1_THEID/2-362                 ........KVTISVIKADIGGYVGHSSTHPEVVAKVEEYAKAGVEKGTLLDASVITCGDDIAIVMTHTKGKDNEEIH.KLAWDAFVAGT.EVAKKLKLYGAGQDLLADAFSGNVKGMGPGVAEMEIEE......RKSEPFIVYFADKTSPSAWNLALYEMFADPMNTAGLVIDPSMHDGFTFEVMDVYS.....GKAVKLETPRELYDLLVFIGATSRYVVRAVYRN......RDGE.IAAVASTQKLSLMAGRYVGKDDPVLIVRCQSGFPAVGEALEPFA.RPW.LVEGWMRGSHTGPLMPVSFKEAKP..........TRFDGPPRVIAAGYQLC.EGKLVG............P.NDLFDDPAFDDARNRCALLANQLRRQGIFEPHRLPPEEMEYT.TLPKVLEKLKDRF-v............................
E3GZ16_METFV/2-362                 ........KTTISVIKADIGSVAGHVVAHKALKDKCREVLSKAKEDGIIEDFYVTNCGDDVNLIMTHRRGEDDEEVH.RTAWEAFKEAT.KVSKKMKLYGAGQDLLSDTFSGNVKGLGPGCAEMEFKE......RPSDPVVVFCCDKTEPGAFNLPLFRIFADPFNTAGLVIDPSLHKGYKFEVYDVID.....HKRVMMSCPEEMYDLLALLGSISRYVIKKIYRK......KDDE.IAASVSTERLNLIAGKYIGKDDPVAIVRAQSGFPATGEILEAFA.QPH.LVGGWMRGSHNGPLMPVSEKDAVP..........TRFDGPPRVMALGFQIS.ECKLIG............P.IDLFDDPIFERSRRLAANISEYMRRHGPFEPHRLPSDEMEYT.TLPDVLKKLKDRFE.............................
Q3AD99_CARHZ/3-359                 ........KITVTVIKADVGGFVGHSSVHEELLATAREQLAKS---PLLVDFHVTHVGDDINLIMTHRQGVDSEEIH.KLAWDTFVACT.EVAKKLKLYGAGQDLLADAFSGNVKGLGPGIAEMEFFE......RTSEPIIVFAADKTEPGAWNLPLYKMFADPFNTIGLVIDPKMHEGFKFEVLDLLE.....NKKIIFNTPEDLYDLLVFIGAPGRYCVKSVYTK......-AGE.IAATSSTQRLNLMAGRYIGKDDPVLIVRCQSGLPAVGEALEPFA.RPH.LVSGWMRGSHSGPLMPVSVADATP..........SRFDGPPRVIALGFQLA.DGKLIG............P.QDFFADKAYDRAREMALMIADYMRSLGPFEPHRLHLEEMEYT.TLPLVLEKLKDRF-v............................
T0N266_9EURY/2-366                 ........KVTLTHIKADIGSLPGHTTVHEDVLNEVKRFLKEQSK-GIIWDHFVGYVGDDIQITMVHDNGVNASEVH.KLAWDAFKSGT.EVAKKLGLYGAGQDLLKDSFSGNIKGMGPGIAEMDITP......RRSEPFIVYMMDKTEPGAFNYPIFKMFADPFNTPGLVIDQSMHDGFKFEVWDIQE.....AKAIMLNAPEEMYDIISLIGTKGRYVIKRVYTKke.hgkLPDE.NVAVITTDKLSFIAGEYVGKDDPAAIVRIQSGLPASGEAMEAFS.HPY.LVSGWMRGSFNGPLMPVAMKNSKM..........IRFDGPPRVVALGFVYK.DKKLAG............P.VDMFDDPAYDNARKLANDITDYIRRMGPFEPHRLPEEDMEYT.TLPKVMEKLKGRF-v............................
C9R9G3_AMMDK/3-360                 ........KVTLSVIKADIGGFVGHSAVHPEVKEKARACLEKHP---LLIDYYVAHVGDDLVLIMTHEHGRNKGEIH.KLAWDTFVACT.EVAKKLKLYGAGQDLLADAFSGNVKGLGPGVAEMEVEE......RESEPVVVLMADKTEPGAWNLPLYKIFADPFNTIGLIIDPKMHCGFAFEVRDLIE.....DKKIIFNAPEDLYDMLVFIGAPGRYAIKRVFHR......GTGE.IAAVSSTQRLNLMAGRYVGKDDPVCIVRCQNGYPSVGEVLEPFA.FPH.LVSGWMRGSHSGPLMPVSMDDARP..........TRFDGPPRVVALGFQLA.DGKLIG............P.NDFFSDPAFDNARRLALEIADYLRRLGPFEPHRLHLDEMEYT.TMPQVMEKLRDRF-i............................
Q9HIB3_THEAC/2-366                 ........KVTISHIKADIGSLPGHSIVDEKVMARIQEYIEDHGKN-LISDFRMAHVGDDAQITMVHTKGIDSSEIH.ELAWNAFKAGT.EVAKKLGLYGAGQDLLKDSFSGNLKGMGPGVAEMEINE......RPSEPFIVYMMDKTEPGAFNLPIYKMFADPFNTPGLVIDEAMHSGFRFEVWDVIE.....HKAIFLDAPEYLYDLLALIGSKERYVIKRVYTKke.nkkLPEE.NVAVISTDKLSLIAGKYVGKDDPAAVVRIQSGLPAAGESLEAFA.FPY.LVSGWMRGSFNGPLMPVGMKDAKM..........TRFDGPPRVVALGYVLK.SGKLEG............P.VDMFDDPAFDYARRVAGEMTDHLRRMGPFEPHRLPDQEMEYT.TLPVVMEKLKDRF-v............................
Q9YD03_AERPE/6-366                 .......t-TTVSVIKADIGSLAGHHRVHPDTILAASRVLAEAKRKGVIKSFYVTNAGDDLQLIMTHFKGVDNPEIH.ELAWTAFREAT.KVAKDLGLYAAGQDLLSDAFSGNIRGLGPGVAEMEFVE......RPSEPIVVFMADKTEPGAFNLPLYKIFADPFNTAGLVIDPRLHDGFIFEVLDVFE.....GKAVELRAPEEIYDLLALIGTPSRYVVKRVYRK......SDRE.IAAVVSSERLSLIAGRYVGKDDPVMIVRAQSGFPAVGEVLEPFA.FPH.LVAGWMRGSHHGPLMPVGLKDSKV..........SRFDGPPRVIALGFQVK.NGELIG............P.ADLFDDPAFDEARRQAQMIADYIRRHGPFMPHRLGPEEMEYT.TLPEVLKRLKDRFK.............................
F8C4Z5_THEGP/2-362                 ........KLTLSVIKADIGGFVGHSSVHKDVIEKVKEVAEDGKDKGIIRDVSILVCGDDIALVMTHTKGVDSSEVH.ELAWNAFKEGT.EVAKKLKMYGAGQDLLADAFSGNIKGMGPGVAEMEFVE......RKSEPVVIFFADKTAPSAWNLPLYEIFADPMNTAGLVIDPSMHDGFIFDVMDVYT.....GMGIMLKAPEELYDLLVFIGATSRYVVRAVYRK......SDGE.IAASASTQRLSLMAGRYVGKDDPVLIVRAQAGFPAVGEILEPFA.RPW.LVEGWMRGSHTGPLMPVSFKNAKP..........TRFDGPPRVIAAGYQIT.DGYLIG............P.SDLFDDPAFDEARRQCNVMADILRRQGIFEPHRLPPEEMEYT.TLPKVLEKLKDRFK.............................
D9Q2U6_ACIS3/7-366                 ........KTTLSVIKADIGSIAGHHKAHPDTLLAASRVLAEGKKKGIIADFYVTAIGDDIQLIMTHFRGVNDPQVH.ELAWSAFKEAT.SVAKDLGLYAAGQDLLSDTFSGNVRGLGPGVAELEFNE......RPSEPVAIFMADKTEPSAFNLPLYKIFADPFNTAGLVIDPKMHSGFVFTVLDLYE.....GKAVDLSTPEELYDLLALIGTTSRYVIKYVHRK......-DGE.PAAVVSSERLNLIAGKYIGKDDPVMIVRLQSGFPALGEALEAFS.FPH.LVAGWMRGSHFGPLMPVGLKDAKM..........TRFDGPPRVLGLGFNIK.AGRLVG............P.TDLFDDVAFDEVRRQAAEIADYMRRHGPFMPHRLGPEEMEYT.TLPDVLKRLEGRFR.............................
Q8ZY51_PYRAE/2-372                 ........KITVSIIKADVGGFPGHAHVHPKMLEYAAAKLKEAQRKGVIIDYFVYNVGDDISLLMTHTKGEDNPDIH.GLAWETFREITeQVAKKYKLYGAGQDLLKDAFSGNVRGMGPQVAEMEFDE......RPSEPLVVFAADKTEPGAFNLPLYKMFADPFNTAGLVIDPSMHEGFIFEVLDVVE.....HKVYLLKTPEESYYLLGLIGTTGRYIIRKVFRR......ADGA.PAAANSVERLSLIAGRYVGKDDPVMMVRAQSGLPAVGEILEAFS.HPH.LVHGWMRGSHAGPLMPARFISVDPerriaigakmTRFDGPPKVGALGFQLH.DGYLEG............A.VDLFDDPAFDYVRQVAAQIADYIRRMGPFQPHRLPPEEMEYT.ALPKILAKIKA---yp...........................
O67659_AQUAE/2-362                 ........KVTLSVIKADIGGFVGHSSTHPDVVNAVREHVEKEVEKGNLIDCDILTCGDDIAIVMTHTHGVDAELVH.KIAWDAFMKGT.EVAKKLKLYGAGQDLLTDTFSGNVKGMGPGVAEMEFEE......RPSEPVIVFFADKTSPSAWNLPLYEMFADPMNTAGLVIDPKMHDGFTFEVLDVYT.....GKAVKLNTPAEVYDLLALIGSVGKYVVKNVYRN......YDGE.IAATASTQRLSLIAGQYVGKDDPVLIVRAQSGFPAVGEILEPFA.RPW.IVEGWMRGSHNGPLMPVSFEDARP..........SRFDGPPRVIGAGYQLA.NGKLIG............P.ADMFKDPAFDKARQVAQDMADILRRQGIFEPHRLPAEEMEYT.TLPKVLKKLENRF-y............................
A5UUY1_ROSS1/4-364                 .......e-LTISCIKADVGGFVGHSAIHPALQDEAGRQLEIARRRGMLIDFHVTACGDDLGLLMTHRLGIDNHEVH.RLAWDVFDICT.RVAKELKLYGAGQDLLKDAFSGNVRGMGPGIAEMTIVE......RPSEPIIVFFADKTSAGAWNLPLFRMFADPFNTAGLVISPAMHDGFRFRVLDVRK.....GTTITLSTPEEMYDLLVFIGAPGRYVVERVTAK......STGA.IGAVSSTQRLALIAGRYVGKDDPVCIVRAQGEFPAVGEVLEPFT.MPH.IVEGWMRGSHYGPLMPCRVGDAHP..........GRFDGPPRVIALGFQIA.EGQLIG............P.RDMFDDPSFDEARHLCNVIADHLRRHGPFEPHRLPMEEMEYT.TLPEVMKKLADRWQ.............................
F4BZ11_METCG/3-368                 ........KITISLIKADVGGYPGHCSVHPELIKTAEEKLEEAKKSGCLVDYRVMACGDDLELLMSHRTGCDCGDIH.GLAWETFEAAT.ETAKGLKLYGYGQDLLADAFSGNIKGMGPGVAEMEITE......RTAEPIIAFMMDKTEPGAFNLPIFKMFADPFNTAGLIIDPSFHHGFTFEVWDILE.....HKKVLMNCPEEMYDMLALIGAKSRYVIKRVFAKpg.skiPQSE.PVAVISTEKLYQTAGKYVGKDDPVALVRSQSGLPALGEVLEPFS.IGH.LVSGWMRGSHNGPLMPCSFDTAHP..........TRFDGPPRVIAAGFQLA.EGKFVG............P.VDLFNDLAFDRVRQRCLEITDYMRAHGPFEPHRLPMEEMEYT.TLPHVMDCLRDRF-v............................
M1E4F8_9FIRM/221-281               ilralven---------------------------------------------------------------------.-----------.--------------------------------------......-------------------------------------------------------.....---------------------------------......----.--------------------------------------------.---.-------------TLPVTFYDSS-..........-NALAFPKSLAVGFTLQ.NGKLFG............P.VDLFDDSFYESLRSKFYE------------------------.--------------kn...........................
A3DMZ2_STAMF/6-366                 ........KITLSIIKADVGSMSGHVMPHPDQLAAATKVLAEAKQKGLLIDFYVTHVGDDIQLIMTHRKGVDAPEIH.ELAWNAFQAAA.KVAKELKLYAAGQDLLSDAFSGNVRGLGPGVAEIEMVE......RKAETVITFHADKTEPGAFNLPIFRIFADPFNTAGLVIDPRMHEGFIFEVYDVFE.....GKSVKLSAPEEMYDILALIGTPSRYVVRRVYRK......SDNL.QAAVVSVERLNLIAGKYVGKDDPVAIVRAQHGLPAVGEVLEAFS.FPH.LVAGWMRGSHHGPLIPVPQRYARV..........TRFDGPPRVMALGWNIA.KGRLIG............P.VDLFDDVAFDETRKLGVQIAEYMRRHGPFMPHRLGPEEMEYT.TLPAVLEKLKDRF-v............................
K0I7L4_NITGG/2-361                 ........QITVSAIKADIGGIGGHTRPSDELLETVRNFVAKNSK-GLLIDHYIGYTGDDIHIIMTHTRGVDDEKIH.KLAWDAFTEGT.KTAKEQGLYGAGQDLLKDSFSGNVKGMGPGVAEIEMEE......RPSEVFCIFAADKTEPGAFNFPLWRMFVDARSNSGLLINERLAEGVVFRIMDVMT.....GKVAELKMWQDKAELEAALMYPGRYVVHSVVSA......DGTD.QIVSASTDRLHNIAGTYVGKDDPIAIVRTQKNFPATEEAGSAFN.DPH.YVAGNTRGSHHMPLMPVKLNSAA-..........SLNYSIPIVSCLLFSMH.NGKLTG............P.HDGFGTADWDLQRMWAAERAMIMRNQGFIHPATLVPDELEYNkGYEARMSKLESKFR.............................
K4LFM4_THEPS/4-361                 ........KITLTVIKADVGGCVGHSSVHPELLEKAKEMLSGS---PLLIDSYVTHVGDDINLIMTHEAGRNNGEVH.QLAWDVFVACT.DVAKKLKLYGAGQDLLADAFSGNIKGLGPGIAEMEFEE......RESEPVIIFMADKTEPGAWNLPLYKMFADPFNTIGLVIDPKMHKGFDFDVRDTVE.....NKKIIFSTPEEIYDMLVFIGAPGRFCVKRVFQR......ETGD.IAAVSSTQRLNLMAGRYVGKDDPVCIVRCQSGFPAVGEALEPFT.YPH.LVAGWMRGSHNGPLMPVALKDAHP..........TRFDGPPRVIALGFQLS.EGKLIG............P.QDLFDDPAFDRARELANNVADYMRRMGPFEPHRLPLDEMEYT.TMPQVSKRLKERF-i............................
F2KSE7_ARCVS/4-369                 ........KITVSLIKADVGSVPGHVVVPDEIKKVAEAFLEEKKQNGDIIDYRVLNVGDDLELIMTHREGVDSEKIH.GIAWETFELAT.KRAKELKLYGAGQDLLKEAFSGNIRGLGPGVAEMEFTE......RGAEPLLAFMMDKTEPGAFNLPIFRIFADPFNTAGLVIDPSLHNGFVFEIWDIVE.....HKRVFMNSPEEMYDILALIGGKSRFVIKRIFPKeg.sklPADE.PVATVSTEKLFQIAGEYVGKDDPVALVRAQSGLPAVGEVLEPFA.FPH.LVSGWMRGSHNGPIMPVPFHYAKC..........TRFDGPPRVIGAGFQIC.NGKLVG............P.VDLFDDPAFDYTRQKAAEIAEYMRRHGPFEPHRLPHEDMEYT.TLPKVLDKLKDRFE.............................
A9A3J9_NITMS/5-362                 ........KITVSVIKADVGGVGGHTKPSDGLLDAIRNTVKNSA--DLLIDYYIGYCGDDTHIVMSHTHGVDNQQIH.KLAWDAFMAGT.QVAKEEGLYGAGQDLLKDSFSGNVKGMGPGVAEMEFEE......RPNEAFTVFAADKTEPGAFNYPIYRMFVDALSNTGLIVNKNLADGVKINIMDVEK.....AQIAELQLWEDKPTIEAALMYPGRYVVDSVTTK......-DGE.PILAASTDRLHNIAGTYVGKDDPICVVRTQKKFPATEEVGSVFN.NPH.FVAGNTRGSHNMPLMPVKLNSAA-..........TINFCIPIVEALVFSMH.NGKFTG............P.FDGFSTPDWDLIRERATEKAMAIRSQGFIHPATLVPSELEYAeGYRARMDVLESKM-k............................
Y299_METJA/8-367                   ........KVTISVIKADVGGLCGHTLAPDELLEACEAVLEEAVDE-IILDYYVTRCGDDIDLIMSHKLGCDNEKVH.GLAWRAFEEAT.KVAKELKLYGAGQDLLADSFSGNVRGMGPGCAEMEFVE......RKSEPIVVFCCDKTDPTAFNYPLFKMFADPFNTAGLVFDPSMISGFKFEVHDVVG.....HKKVFLDTPEEMYMLLALIGDYEKYAIKRVYRR......RDNE.IAAVVSTEKLNYIAGEYVGKDDPVAIVRAQSGFPAVGEVLEPFA.NPH.FVPGWMRGSHWGPLMPVGEEDATP..........TRFDGPARIIALGFQVC.DGMLIG............P.NDLFADKGFDKAREKALEMADIIRRMGPFQPHRLPATMMEYT.TVPKVLEALEDRF-i............................
A2ST38_METLZ/2-115                 .......h-TTVSVFAKPVGGVSGTTRVFPDILQTAAKMLKKAEG-GILTDSFVTHTADRLVLIAVHDPDVLPDT--.-LIAAVFSAAE.ELAQKRHLF-----------------------------......-------------------------------------------------------.....---------------------------------......----.--------------------------------------------.---.------------------------..........-----------------.------............-.------------------------------------------.--------------cdaapvsvcrmtiperanepfllflagsd
Q83E23_COXBU/2-377                 ........EITLSAIKADVGSIGGHTQPSIEMLQAVQQSLQKNIDSGLLIDGLVTFTGDDIAIICSHQQGLNNEDVHvGFAWQAFLAAT.EVAKEQGNYGAGQDLLVDAPSGNVRGAGPGVAEIEFTLnpksnyRPAESFMIFAGDKCAPGAFNLPLYLVFCDPMHNGGILLNPKIHLGWVFTVIDMDYkgedeDRIIQLSVPERSWDVAALLQNPDRYAVESIRSR.....yKPEE.QVVSVSATRLHNIAGKYTGKDDPIAIIRSQGIFPAPEEIIEPYStINQ.IISGDARGSHNMPQLPVPINTPV-..........TGPYCHPLISALGFSMNkQGKFAG............RyVDFFAGSAWDYARYVSQRRAAEIRRQGFMGIAMAQEAEIAYT.GLVDTWKKLDDEFE.............................
E6P8F5_9ARCH/2-370                 ........RTTVSVIKADVGSIAGHHKPHPKMMELASGKLAEAENTGLIKSGYATHCGDDIILVMSHGKGEDNPEIH.GLAWNIFREITeKVAKPMKLYGAGQDLLSDAFSGNVRGLGPGVAEIEFEE......RKSDPVIVFAADKTEPGAWNLPLYRIFASPENTAGLVIDPTLHDGFRFEVLDLVE.....SWSVLLKTPEELYDLVALLGTVGRYAVSKVYRA......SDGE.PAAAASTTRLSLIAGRYVGKDDPVMIVRAQAGFPAVGEVLAAFA.TPF.IVSGWMRGSHRGPLMPVSFRRGQNv........vSYFDGPPRVMAMGWQVS.NGRLVGqd.......gveP.VDLFEDPFWDTVRNKAADLALTLRTMGEFEPARLGHEEMEYT.TLPQIIEKLKPRFK.............................
D7E6J1_METEZ/2-367                 .......e-TTFSAIKADVGSVAGHHVVPEELEESAISVLEEAKGK-DIFDYFVTHCGDDLELIITHDKGEDSEEVY.EIAWNAFLKAT.EKAKELGLYGAGQDLLSDAFSGNIKGMGPGIAEMEFKE......RKSNPVFTFMMDKTEPGAFNLPMYKIFADPFNTAGLVLDPNMHSGFVFEVWDIKE.....SKKINFYCPNDLYDMLALIGAKSRYVIKRVYPKednpkaTSQE.PAAVISTEKLSHIAGEYVGKDDPVAVVRGQSGLPAAGEILEPFT.HPE.LVSGWMKGSHNGPLMPVPVEDATP..........TRFDGPPRAICLGFQVK.DGMLIG............P.VDSFADPAFDKTREKAHQVSDYMRAHGPFEPHRLPEEEMEYT.TLPDVMEKINHRFE.............................
B1I5L9_DESAP/4-361                 .......t-VTLSVIKADIGGFVGHSGVHPELLEKAKGILSGS---PLLIDFHVTHVGDDINLILTHELGRNNGEIH.QLAWDTFVACT.EVAKKLKLYGAGQDLLGDAFSGNIKGLGPGVAEIEVVE......RKSEPVIVLMADKTEPGAWNLPLYRIFADPFNTIGLVIDPNMHGGFNFEVRDLIA.....HKKIIFSAPEDIYDMLVFIGAPGRYAIKRVFHK......ANGQ.IAASSSTQRLNLMAGRYVGKDDPVCIIRCQSGFPAVGEVLEAFA.RPH.LVSGWMRGSHSGPLMPVSVTNSCP..........TRFDGPPRVVALGFQLA.QGKLIG............P.QDMFDDPAFDRARALCNEIADYMRSLGPFEPHRLPLDEMEYT.TMPLVMSKLKDRF-i............................
G7WRF4_METH6/3-367                 ........KITISLIKADVGGWPGHATVHPALKETAESVLSQEKAKGEIIDFKVMSVGDDLQLMMTHQRGVDNAEIH.GLAWEVMCKAT.EKAKELKLYGAGQDLLCDAFCGNIKGMGPGVAEMEFEE......RAAEPVVAFMMDKTEPGAFNLPIFRIFADPFNTAGLVIDPSIHQGFVFEVWDIME.....HKKVMMDSPEEMYDILALIGAKSRYVIKRVYPKag..klPEDE.PAAVVSTEKLYQTAGTYVGKDDPVALVRAQSGLPALGEVLEPFS.LGH.LVSGWMRGSHNGPLMPCAFEDAVC..........TRFDGPPRVIAAGFQIA.KGMLIG............P.VDLFRDPAFDLTRQRVHEITDYMRRHGPFEPHRLPMEDMEYT.TLPHVLKNLGERF-a............................
B0KD99_THEP3/3-360                 ........KITLTVIKADVGGFVGHTDVHPELLEIAKKHLKEKGK--MLIDFHVTRVGDDIELIMTHREGIDNEEVH.KLAWDALWSCG.EKAKELKLYGAGQDLLKDSFSGNIKGLGPGVAEMEIEE......RKSEPVIIFMADKTEPGAWNLPLYKMFADPFNTVGLAIDPNMHQGFKFEVYDMIG.....HKKIIFETPEDIYDMLVFIGATGRYCIRRVYTK......-NNE.IAAVSSTQRMNFMAGKYIGKDDPVLIVRCQNGLPAVGEALEPFA.NPY.LVAGWMRGSHNGPMIPVSLEDAVP..........TRFDGPPRVCALGFQLA.EGKLIG............P.QDFFKDVAFDNAREKALEIADYIRKMGPFEPHRLPLEELEYT.TLPHVVKKLQGRWK.............................
D9S0X7_THEOJ/3-361                 ........KITLTVIKADIGGYVGHCSVHPDLIEEAKSVLEEKG-KGLLEDYVVTHVGDDINLIMTHRKGVDNTEIH.KLAWDTFLSCT.QIAKKLKLYGAGQDLLSDSFSGNIKGMGPGVAEMEFEE......RPSEPVIVFMADKTEPGAWNLPLYKMFADPFNTIGLVIDPKMHQGFKFEVLDTIE.....NKKIVFSCPEELYDLLVFLGAANRYAVKAVYSK......-SGE.PAAVSSTQRMNLMAGRYVGKDDPVLIVRCQSGLPAVGEALEPFA.NPH.LVAGWMRGSHFGPLMPVSCNGATP..........SRFDGPPRVVALGFQLA.GGKLVG............P.QDMFADVSFDRAREKALEMADYFRQLGPFEPHRLPLDEMEYT.TLPQVMEKLKDRFE.............................
H3ZMW0_THELN/6-372                 ........KITISVIKADIGGWPGHCKVHPALIEKANELLGKAKEEGTIIDFYATYCGDDLQLIMTHKHGVDSEKIH.GLAWNVFKEAT.EIAKELGLYGAGQDLLKDAFSGNVRGMGPGVAEMEITL......RKSEPIVTFHMDKTEPGAFNLPIFRMFADPFNTAGLVIDPHMHMGFRFEIWDIKE.....HKRVIMNSPEELYDILALIGAKSRYVIKRVYPKkg.hklPEDE.PVAVISTEKLYEIAGEYVGKDDPVAIVRAQSGLPALGEVLEPFA.FPH.LVSGWMRGSHNGPIMPVPLKYATP..........SRFDGPPRVVALGWQINkDGKLIG............P.VDLFEDVAFDEARKKALEIADYIRRHGPFEPHRLPLEEMEYT.TLPGVLEKLKDRFE.............................
B8GG85_METPE/6-298                 ......is--TITVAVRAVGGYPGHARIHPKVLERAARVVKEQVKAGTVTDSGIIHCGDLLGLILTGAIPDD-----.-LIERTFTAGQ.NEATELHLCPS---------QGNSL-----TLELTLTE......REHEPVLVLMTDTGRTVA--QILYRIFADPLMTTRLVSDPCLREGFVFELT-LLD.....GVQHRYTTPGETYQLLGCLTDEEMKGIR-VLK-......QDGT.IAAVAGIERTG-----------GAIIIRTEGSFPSVDEVLAPFL.SPH.LMAGM-------TLMPVSICDAHT..........TKATSPSRITAFGFALN.RGRLIG............P.ADLFDDPAFDPSRQAAVRMAGTRRMQGPFRP-----------.--------------.............................
A8A9E4_IGNH4/4-363                 ........KTTISVIKADIGSLAGHHTVHPDCMAAASRVLAEAKKNGVINDFYVTHVGDDLILIMTHTKGVDHPDVH.GLAWEAFKKAA.EVAKELGLYAAGQDLLSDAFSGNVRGLGPAAAEMEIEE......RPSEPIVIFAADKTEPGAFNLPLYKIFADPFNTAGLVIDPRLHDGFVFEVVDVFE.....DKGVHLNTPEELYDLLALIGTPSRYVIRRVFRK......-DGK.IAAVVSVERLNLIAGKYVGKDDPVMIVRAQSGFPAVGEVLEPFT.FPH.LVAGWMRGSHNGPLMPVPVRDARP..........TRFDGPPRVIALGFQVK.NAKLVG............P.SDLFDDPAFDEARRTANKVADYIRRHGPFMPHRLDPSEMEYT.TLPQVLERLKDRFK.............................
D8PEU2_9BACT/8-368                 ........KITLSVIKADIGGFVGHSAMHPALMDCANEKLAAAKSGGLLVDYHVSACGDDLQLIMTHRHGVDHEPIH.RLAWDTFEAGT.AVAKELHLYGAGQDLLADAFSGNVRGQGPGVAEMEFVE......RKSDPVLIFMADKTSAGAWNLPLYKMFADPFNTAGLVIAPTLHQGFRFEVHDIYE.....HKKISFDCPEELYDMLMFIGSPGKYTIKYVYSR......ADGT.IAAASSTERLSLIAGKYVGKDDPVMIVRAQQNFPAVGEVLDPFR.YPW.IIEGWMRGSHYGPLMPVSVKQATP..........TRFDGPPRVACLGFQLA.DGKLVG............P.RDMFDDPSYDEARRDANRIADVLRMHGPFEPHRLPLDDMEYT.TMPQIMKKLEGRW-a............................
A4FCE3_SACEN/1-361                 .......m-VTLSIIKADTGGFVGHSAVHPEMVTEARDAVSTAVGDGLLLDGKVASCGDDLSLIMTHERGADAEEVH.SFAWDVFGRTT.GIAKRLGLYGAGQDLLSDAFSGNLRGMGPGYAELEFTE......RPSEPVVCFLADKTEPGAWNLPLYKIFADPFNTAGLVIDAKMHAGFRFEVYDLFE.....EKRIWFDCPSELYEMLMFIGAPARYVIHSVESK......TLDE.QAVATSTQRLSLIAGKYVGKDDPVMIVRCQSGLPALGEVLEPFA.FAY.TAGGCMRGSHHAPMMPVSTGDAHP..........ARFDGPPRVVALGFQVH.ESKLIG............P.RDLFDDPSFDRARAQCNEVMDYLRRHGPFEPHRLPLEDLEYT.TMATLEKRLADRWQ.............................
Q5SJM8_THET8/2-363                 ........KVTLSVLKADIGSVGGHTLPSRKVLAKVEEVVREEVGR-LLLDAYVFHIGDDIVLLLSHTRGVRNQEVH.ALAWKAFREGT.EVAKAEGLYGAGQDLLKDAFTGNLHGLGPQVAEMEFTE......RPAEPFMVLAADKTEPGAFNLPLYLAFADPMYSSGLLLSPELRPGFRFRIMDLAQt..erDSYIELDAPERLYDIATLLRDSHRFAIESIWSR......KHGE.QAAVVSTTRLRNIAGRYVGKDDPVAIVRTQKIFPATEEFGPVFA.LAP.YVAGDTRGSHHMPLMPVRANTPA-..........STFFCVPMVCGLAFSLR.EGRLSE............P.VDLFADPVWEAVRAKVVEKAQEMRRQGFYGPAMLPMEELEYT.GIAERLKALEREF-s............................
D3DG54_HYDTT/2-362                 ........RITLSVIKADVGGYVGHSGVHPQLVETIKEFVQEEVKKGILIDASVLVCGDDTAIVMTHTHGVDSEIVH.GIAWRAFEKAT.EVAKKLKLYGAGQDLLSTAFSGNVKGMGPGVAEMEFEE......RPSEPVIVFFADKTAPSAWNLPLYEMFADPMVCAGLVIDPKMHDGFTFEVLDTYT.....GKAVKLSTPSELYELLALIGTVERYAIRSVWRN......NDGE.IAAVASTQRLSLIAGKYVGKDDPVMVVRAQAGFPAVGEILEPFA.RPW.IVEGWMRGSHNGPLMPVSFKNATP..........TRFDGPPRVIAAGYQIA.EGKLIG............P.RDLFDDPAFDKAREQAQLMADMLRRQGIFEPHRLPSEEMEYT.TLPKILKKLEERF-y............................
Q3Z761_DEHM1/2-361                 ........KVTLSVIKADIGGFVGHSDSHPQCLVRAEKHLAEAKKNGMLIDYHITKCGDDLQLVMTHQKGINNKVIH.EMAWDTFVSCT.EVAKELKLYGAGQDLLCDAFSGNVKGMGPGVAEMELEE......RPSEPIIIFMADKTSSGAWNLPLYKMFADPFNTIGLVIAENMHDGFSFEVHDVKE.....SKGISFNTPEEIYDMLVFIGAHSRFAIKSVSTR......-KGE.IAAVSSTQKLAFLADRYVGKDDPVCIVRAQGSFPAVGEILEPFA.QPY.LVEGWMRGSHNGPIMPVSIEDSTP..........TRFDGPPRVTALGFQLS.NGMLIG............P.RDMFKDKSFDNARQKSLDMADMMRSHGPFEPHRLPLEEMEYT.TMPQVSKKLAGRFK.............................
Q2NGI0_METST/2-362                 ........KTTVSIIKADIGSVGGHAVTHQKLKDKCNEYLSNAKEEGLLTDFYITNCGDDIDMIMTHTNGTDNEEVH.KLAFDTFMAGA.EVAKGLKLYGAGQDLLSDTFSGNIKGMGPGSAEMEFKE......RGSDPVFAYCCDKTEPGAFNLPLFRMFADPFNTAGLVIDPSLHGGFDFEVYDVIE.....NRKVVMSCPDEMYDLLALIGSTGRYVIKRIFRR......SDNE.IAAAVSTDKLNLMAGKYIGKDDPVAIVRSQSGFPAGGETSEPFA.FPH.LVSGWMRGSHNGPLMPVSQADARP..........VRFDGPPRVIGLGFQVS.EAKLIG............P.VDMFADPAFDDARNTATKVANYMRRHGPFEPHRLPADEMEYT.SLPGVLEKLEDRFE.............................
Q2RG86_MOOTA/4-361                 ........RITLSVIKADIGGFVGHSSVHPRLLETAERYLAESK---LLIDYRVAHVGDDIDLIMTHKYGVDCPEIH.HLAWNVFLQCT.EVARELKLYGAGQDLLSDAFSGNVKGMGPGVAEMEFEE......RKSEPIIVFAADKTEPGAWNLPLYKMFADPFNTIGLVIDPKMHQGFRFEVYDLIK.....NERVEFSLPEELYDLLVFIGAPGRYCIKSVYSK......TTGE.IAAVSSTQRLNLMAGRYVGKDDPVCIVRCQSGLPAVGEALEPFA.NPH.LVAGWMRGSHIGPLMPVGLDQSAP..........TRFDGPPRVVAMGFQLS.GGRLVG............P.QDFFGDVAFDKARQTANEIASYLRSLGPFEPHRLPLEDMEYT.TMPEVMAKLKNRF-v............................
E8N0E8_ANATU/4-363                 ........KLTLSVIKADVGGFVGHSAIHPDLIDTARMALEEARQKGWLIDFHVTACGDDLQLIMTHSRGVDDVEIH.HLAWQVFERCT.AIARKLKLYGAGQDLLTDAFSGNVRGMGPGVAEMELHE......RESEPVIIFMADKTSAGAWNLPLFRMFADPFNTAGLVISPSMHEGFRFEVHDVKQ.....HKRIFFDTPAEMYDLLVFIGASGRYVIKAVYTR......-DGE.IGAVSSTQRLALIAGKYVGKDDPVCIVRSQGKFPAVGEVLEPFT.MPH.IVEGWMRGSHYGPLMPVPVRQATP..........SRFDGPPRVAALGFQLA.NGGLIG............P.RDLFDDPGFDEVRRQVNVLADQLRRHGAFEPHRLPMDEMEYT.TLPQVMEKLAERWE.............................
A4YIZ5_METS5/2-362                 .......r-STVSVIKADIGSLAGHHVVHPDTMAAANRVLAEAKRQGIILDYYITNVGDDLELIMSHTRGELDTKVH.ETAWDAFKEAT.KVSKELGLYAAGQDLLSDSFSGNLKGMGPGIAELDIEE......RPSEPIAIFMADKTEPGAFNLPLYKMFADPFNTAGLVIDPTMNEGFKFEVLDVYE.....GQSVVLNSPEEMYSLLGLIGTPARYVIRRVYRK......ADNM.IGSVTSIERLNLIAGKYVGKDDPVLIVRLQHGFPALGEALEAFS.FPY.LVPGWMRGSHYGPIMPVSQRDAKA..........TRFDGPPRLIGLGFNVK.NGKLTG............P.SDLFDDPAFDETRRMASVITDYMRRHGPFMPHRLEPTEMEYT.TLPTLIEKLKPRFK.............................
T0M774_9EURY/1-223                 ........---------------------------------------------------------------------.-----------.--------------------------------------......-------------------------MFADPFNTPGLVIDNNMHDGFTFEIWDIIE.....AKRIFLSAPEHMYDILGMIGSKGRYVIKRVFTKpn.hekLPDE.NVAVITTDKLSFIAGEYVGKDDPAGIVRIQSGLPASGESLEAFS.HPY.LVSGWMRGSFNGPLMPVGMKYAKM..........TRFDGPPRVVSLGFVLK.NGKLSG............P.VDMFDDPAFDGARRTAVDVVDYLRRMGPFEPHRLPEEDMEYT.SLPRVLEKFKGQFE.............................
I0A1U2_FERFK/6-365                 ........KVTLSIIKADVGGLAGHHVVHPDLIATATRMLSEAKESGIIEDFYVTNVGDDLQLIMTHYRGVDSKDVH.SLAWDTFKEAT.KVAQKLGLYGAGQDLLSDAFSGNVRGMGPGVAEMEFIE......RTSEPVVAFMADKTEPGAFNLPFYKIYADPFNTAGLVIDPKLHSGFKFEIWDLIE.....HKQYFLNAPEDSYDILALIGTTGRFTIKRVYRK......DNNE.IAAAVSSERLNLIAGKYVGKDDPVAIARAQSGFPALGEILEPFS.FPH.LVAGWMRGSHNGPLMPVSQKDARC..........TRFDGPPRIIALGFNIK.DGKLIG............P.TDLFDDPAFDETRRTAQIIADYMRRHGPFMPHRLGPEEMEYT.TLPQVLKKLEEK--k............................
C9RC35_AMMDK/4-361                 ........KITVTVIKADVGGLVGHTSVHPELLEKARGVLSGS---PLLIDFYVTSVGDDINLIMTHELGRNNGEIH.KLAWDTFVACT.EVAKKLKLYGAGQDLLADAFSGNIKGLGPGIAEMEVEE......RESEPIVIFMADKTEPGAWNLPLYKIFADPFNTIGLVIDPKMHCGFTFEVRDLIE.....NKKIMFNAPEDIYDMLVFIGAPGRYAIKRIFHR......ETGQ.IAAVSSVQRLNLIAGRYIGKDDPVCIVRCQSGYPAVGEVLEPFA.HPH.LVSGWMRGSHSGPLMPVSLKDARP..........SRFDGPPRVVALGFQLA.DGKLIG............P.QDLFDDPAFDRAREMANIIADYMRRLGPFEPHRLHLDEMEYT.TMPMVMQKLKDRF-i............................
D3RYX0_FERPA/3-368                 ........KITVSLIKADVGSVAGHTTVADELIKIAENNLSEAKESGLIIDFRVFKAGDDLELLMTHTKGVDNEEIH.RLAWETFEKAA.EKAKELKLYGAGQDLLADAFSGNVRGMGPGVAEMEFTE......RKAEPLIAFMMDKTEPGAFNLPIFRIFADPFNTAGLVIDPSMHQGFVFEIWDIME.....HKRVFMKAPEEMYDILALIGAKSRFVIKRVYPKpg.gklPEDE.PVAVVSTEKLYQVAGEYVGKDDPVALVRAQSGLPAVGEVLEAFA.FPH.LVSGWMRGSHNGPLMPVSFKYAKC..........TRFDGPPRVVAAGFQLS.NGKLIG............P.VDLFDDPAFDYTRQKAMEIAEYMRRHGPFEPHRLPREEMEYT.TLPKVMEKLKERFE.............................
F2NM38_MARHT/2-364                 ........RLTLSMLKADIGAVGGHTAPSPEVLARVREVITEGQRA-VFLDSLVFHCGDDIVVALTHTRDPGDPEVH.ALAWEAFQEGT.RVAQAQGLYGAGQDLLKDAFSGNLVGLGPQVAELQFEE......RPNEPVVLLAADKTEPGAYNLPLYLAFADPMHSPGLLLSPGLQAGFRFRVMDVEAt..eaEHVIDLAAPERLYDLAILLRDPHRFVIESIWSR.....kYPDE.QAVAVSTTRLRNIAGRYVGKDDPVAIVRVQKIFPATEELGPCFA.LAP.FVAGDTRGSHHLPLMPVPANTPA-..........SSYFCMPMVMGLAVSIK.NGRFTR............P.VDMFSDPVWEHVRRHVVEKAMEMRRQGFVEPAMLPYGELEYT.GIRDRLERLLEEF-t............................
A0A0A7LBV6_9EURY/5-378             ........KVTVSVIKADVGSVVGHSRPHPSMMQAAKKILTEKQKQGVLEDFYVTRVGDDINLFMTHYKGENNKEIH.GAAWDCFQEAT.KIAKSMKLYAAGQDILTDAFSGNVKGAGPGSAEMTFEE......RGSEPMLFFMADKTEPSAYSPILSRIYLDPFTTTGLVVDARAKKGFDVEIHDVLD.....HKKVVMSSPEETLNILALLGDTSRYAIKRVSSR......AGIG.PACVVSTDKLNMTAGKYVGKDDPVCICRSQSGLPSVGEYTQPFL.MTSwIAGGWMRGSHYGTFYPCSPEDSDP..........TYFDGPPRICCLGFQLN.NGKLQGleplntkggdhiP.VDFFGNPTFDSARANAIKTSKFLRTQGPFTPSILPAEEMEYT.SRPEVIKELKSRFE.............................
A1RWM6_THEPD/2-363                 ........RITVSLIKADVGGLAGHVVVHPKLEELARKRLEEARETGLLIDFYVYHVGDDLQLLMTHTKGENNAEIH.KLAWDIFVEVTeKVSKPLKLYGAGQDLLKDTFSGNIKGMGPGCAEMEFEE......RRSEPILVFSADKTEPGAWNYKLYRIFADPFNTAGLIIDPAMHSGFIFEVVDVYE.....HKSVKLSTPEESYDLLALIGTPGRYVVKRVYRK......SDGE.IAAVSSATRLSLIAGRYVGKDDPVLIIRAQHGFPATGEVLEAFA.FPH.LVAGWMRGSHTGPLMPVPLRYAQC..........TRFDGPPRVVGLGFQLH.DGRLEG............P.VDLFDDPAFEMTRRMAEEVADYMRRHGPFMPHRLGPEEMEYT.TLPSVLEKLKARF-v............................
Q4JAX4_SULAC/2-362                 ........KTTISVIKADIGSLAGHHVVHPDTMAAASKVLAEAKSQSLLIDYYITHVGDDLELIMTHTRGELDTKVH.ETAWNAFKEAA.KVAKELGLYAAGQDLLSDSFSGNVRGLGPGVAEIEVEE......RPSEPIAIFMADKTEPGAFNLPLYKMFADPFNTPGLVIDPTMHNGFKFEVLDVYQ.....GEAVVLNAPQELYDLLALIGTPSRYVIRRIYRS......EDNL.LGAVVSIERLNLIAGKYVGKDDPVTIVRLQHGLPALGEALEAFT.LPH.LVPGWMRGSHYGPLIPVSQRDARA..........TRFDGPPRLIGLGFNVK.NGKLVG............P.SDLFDDPAFDEVRRLANTITDYMRRHGPFMPHRLEPTEMEYT.TLPIILEKLRSRFK.............................
Q8NKR9_THEKO/6-372                 ........KITISVIKADIGGWPGHSRVHPQLVETAEDVLSKAVEDGTIIDFYVATCGDDLQLIMTHKRGVDSPDIH.GLAWKAFEEAT.KVAKELGLYGAGQDLLKDAFSGNVRGMGPGVAEMEITL......RKSEPVVTFHMDKTEPGAFNLPIFRMFADPFNTAGLIIDPKMHMGFRFEVWDILE.....HKRVILNTPEELYDLLALIGAKSRYVIKRVYPKpg.hpiPENE.PVAVVSTEKLYEVAGEYVGKDDPVAIVRAQSGLPALGEVLEPFA.FPH.LVSGWMRGSHNGPLMPVPMHQANP..........TRFDGPPRVVALGWQISpEGKLVG............P.VDLFDDPAFDYARQKALEITEYMRRHGPFEPHRLPLEEMEYT.TLPGVLKRLTDRFE.............................
Q2LW91_SYNAS/1-71                  ........---------------------------------------------------------------------.-----------.--------------------------------------......-------------------------------------------------------.....---------------------------------......----.--------------------------------------------.---.-----MCGFHHGTLMPGVFHAANL..........SRFDGSPRVIAAGFQVC.DGKLSA............R.RDFFC-------------------------------------.--------------vereqtrvkketpstrvsffrpa......
A6UTE1_META3/5-364                 ........KITLSVIKADVGGLCGHTSAPEELMDACEFVLEEALDE-LIIDYYVTKCGDDVDLIMTHQKGTDNKEIH.GLAWSAFEEAT.EVAKELKLYGAGQDLLSEGFTGNVKGMGPGCAEMEFVE......RPSEPVIVFCSDKTDPAAFNLPFYRMFADPFNTPGLVYDKKMQTGFDFDVLDIYQ.....NKKILLNTPKETYQLLALIGNLETYSVKSVYRA......RDGE.IAATCSADKLSKVGGKYVGKDDPVAIVRPQSGMPSVGEILEAFA.KPH.MVPGWMRGCHWGPLMPVGEDDANP..........TRFDGPPRIFALGFQLS.KGRLVG............P.NDFFADVGFDSARKKALEMADMIREMGPFQPHRLSESMMEYS.SIKKVLADLEDRF-v............................
Q89RC1_BRADU/2-370                 ........RLTLSVIKADVGSVGGHTKPSSRMMATVEGEVAKAICNGLLIDGFICHTGDDIAIIMTHTRGEGSSEVH.QLAWKTFLAAT.SVAKTSGLYGAGQDLLADAPSGNIRGAGPGVAELSFDHsl.sgaRPAESFMVFAADKCGPGAYNLPLYLAFADPMYCAGLMLPP-MIKGFRFHVIDMDNt..agDSLLELDAPDDSYHIAALLRDNERFGIDRIISR......THGE.VVVAVSAQRLHAIAGKYTGKDDPVAIVRNQGIFPAPEEIISPFA.KAH.FVGGDARGSHVMPLMPVPLNTPV-..........TGMYCLPIVSCVGFSIDrEGRFAE............SyTDFFDNPAWDEVRRRAQRKAIEMRSQGWSGAAMLPYSELEYG.GFRDTVSGLLKRF-r............................
B5IAB6_ACIB4/3-368                 ........KITISLIKADVGGWPGHSTVHPDLIETAKEALQKAKDEHILEDFHVTGVGDDLQLIMTHRKGVDSEEIH.KLAWNTFEKAT.AVAKELKLYGAGQDLLKDAFSGNIRGMGPGIAEMEITE......RKSEPIVAFMMDKTEPGAFNLPIYRIFADPFNTAGLVIDPSMHDGFKFEVWDIME.....HKKVIMHSPKEMYDLLALIGAKSRYVIKRVYATes.npkVKGE.VVAVVSTEKLYQIAGEYIGKDDPVALVRAQSGCPALGEVLEPFA.FPH.LVSGWMRGSHNGPLMPVSIKQAHC..........TRFDGPPRVAALGFQVA.NGRLVG............P.VDLFDDPAFDRARETAQYIADYMRRHGPFEPHRLPLEEMEYT.TLPKVLTKLKDRFE.............................
D7DUP4_METV3/4-363                 ........KITVSVIKADVGGLCGHTLAPIELLDAVEYVVENAVDE-TLIDYYVTNCGDDIDIVMTHNKGTDNDEVH.KLAWDALTDAT.DVAKELKLYGAGQDLLSDSFSGNVKGLGPGCAEMEFVE......RRSEPLVVFCCDKTDPAAFNLPFYKMFSSPFNTPGLVFDPSMTEGFKYEVMDIID.....HKRVLMSTPVETYSLLALIGNLERYAIKRVYRG......RDNE.IAAVASSEKLNMMAGEYVGKDDPVAIVRAQSGFPAVGEILEAFA.NPH.LVSGWMRGCHWGPMMPVGEEDAMP..........SRFDGPARIMALGFQLS.KGRLVG............P.NDLFADVAFDKARDKALEMAEMMRSMGPFQPHRLPESMMEYT.SVPKVLKTLESRFE.............................
F6CK08_DESK7/4-361                 ........KITVTVIKADVGGCVGHSSVHSALIEKAQGMLKG---SSLLIDSYVAHVGDDINLIMTHELGRNNGEIH.QLAWDTFVACT.EIAKKLKLYGAGQDLLADAFSGNIKGLGPGVAEMEFEE......RKSEPIIIFMADKTEPGAWNLPLYKIFADPFNTAGLVIDPSMHDGFIFEVRDLIE.....NTRVNFSAPEEIYDMLVFIGAPGRYCIKRVFHK......KTGE.IAAVSSTQRLNLMAGRYVGKDDPVCIVRCQSGMPAVGEVLEPFT.KPH.LVSGWMRGSHSGPLMPVSMQQATP..........SRFDGPPRVVALGFQLA.EGKLIG............P.QDFFADPAFDQARQMANEIASYMRSLGPFEPHRLHLDEMEYT.TMPQVLKKLKDRFE.............................
T0NH40_9EURY/2-137                 ........KVTISHIKADIGSLPGHTTVFEPVVKEVENYVKEKGAS-LLSDFYISHVGDDIQITMIHNGGIDNPEVH.ELAWNAFKAGT.VVAKNYGLYGAGQDLLKDSFSGNIKGMGPGIAEMEITP......RTSEPFIVYMMDKTEPR--------------------------------------.....---------------------------------......----.--------------------------------------------.---.------------------------..........-----------------.------............-.------------------------------------------.--------------si...........................
F0LKH3_THEBM/6-372                 ........KITISVIKADIGGWPGHHKVHPALIEKAREILSKAKEEGTIIDFHVTYCGDDLQLIMTHKKGTDSPDIH.GLAWETFKEAT.KTAKELGLYGAGQDLLKDAFSGNIRGMGPGAAEMEITI......RKSEPIVTFHMDKTEPGAFNLPIFRMFADPFNTAGLVIDPNMHMGFRFEIWDIRE.....HKRVIMNSPEEMYDILALIGAKSRYVIKRVFPKeg.hklPKDE.PVAVVSTEKLYEIAGEYVGKDDPVAIVRAQSGLPALGEVLEPFA.FPH.LVSGWMRGSHNGPIMPVPLKYATP..........SRFDGPPRAVALGWQISpEGKLIG............P.VDLFDDPAFDWARQKALEITEYMRRHGPFEPHRLPLEEMEYT.TLPGVLEKLKDRFE.............................
D5VRN5_METIM/5-364                 ........KITVSVIKADVGGLCGHTLAPEDLLEACEGVLEEAVDE-IIIDYYVTRCGDDIDLIMTHKLGCDNEKVH.GLAWKAFEEAT.KVAKELKLYGAGQDLLADSFSGNVRGLGPGCAEMEFVE......RKSEPIVVFCCDKTDPTAFNLPLFKMFADPFNTAGLVFDPSMISGFRFEVHDVIG.....HKKVYLDTPEEMYMLLALIGDYERYAIKRVYRR......KDNE.IAAVVSTEKINYIAGEYVGKDDPVAIVRAQSGFPAVGEVLEPFA.NPH.FVPGWMRGSHWGPLMPVSEEDAKP..........TRFDGPPRIMALGFQLC.DGMLVG............P.NDLFEDKGFDRAREKALEMADIIRRMGPFQPHRLPATMMEYT.TVPKVLKALEDRF-i............................
Q980K6_SULSO/2-362                 ........KTTLSVIKADIGSLAGHHVVHPDTIAAANKILAEAKRNNIISDYYITYVGDDLQLIMTHNRGELDTRVH.ETAWNAFKEAA.KIAKDLGLYAAGQDLLSDSFSGNLRGMGPGIAEIEFEE......RPAEPVVIFMADKTEPGAYNLPLYKIFADPFNTAGLVIDPTMHEGYKFEVLDVYE.....GESIMLNTPEESYDLLALIGTPSRYIVRRVYRK......ADNL.QASVVSVERLNLIAGKYVGKDDPVMVVRAQHGLPALGEILEAFT.VPY.LVPGWMRGSHYGPLMPVSQKDARA..........TRFDGPPRLISLGFNIK.NGKLVG............P.TDLFDDPAFDEVRRTAVIIADYIRKHGPFMPHRLEPQEMEYT.TLPLVIEKLKNRFK.............................
L0ABT5_CALLD/8-367                 ........KITLSVIKADIGSLAGHHKVHPDTMLASTRVLAEAKKNGLLIDYYVTAVGDDLQLIMTHKKGVNNKEVH.ETAWNAFEEAA.KVAKELGLYAAGQDLLSNSFSGNIRGMGPGVAEMEFNE......RPAEPVVVFMADKTEPGAFNLPLYKIFADPFNTAGLVIDPRMHNGFIFTVLDVYE.....GKALDLSTPNDLYDLLALIGTPSRYVIKYVHRK......-DGE.IASTISSERLSLIAGKYIGKDDPVMIVRAQSGFPALGEILEPFS.FPH.LVEGWMRGSHAGPLMPVGIKDAKM..........TRFDGPPRVAALGFNIK.NGNLVG............P.SDLFDDVAFDETRRQAQIIAEYMRRHGPFMPHRLGPEDMEYT.TLPDVLKKLENKFR.............................
O28830_ARCFU/3-368                 ........KVTVSLIKADVGSVAGHTTVPDELKKAAEENLKNAVDSGLIIDFRVFNAGDDLELLMTHDKGVDSEEIH.RLAWETFEKAA.GIAKELKLYGAGQDLLKDAFSGNVRGLGPGVAEMEFTE......RKAEPVIAFMMDKTEPGAFNMPIFRMFADPFNTAGLVIDPTMHQGFVFEIWDIKE.....SKRVFMRTPEEMYDILALIGGKSRFVIKRVYPKeg.gklPADE.PVAVISTEKLYEVAGEYVGKDDPVALVRAQSGLPAVGEVLEPFA.FPH.LVSGWMRGSHNGPIMPVPFKYSKC..........TRFDGPPRCIAAGFQLA.NGKIIG............P.VDMFDDPAFDYTRQKAMEIAEYMRRHGPFEPHRLPSEDMEYT.TLPKVLEKLKGRFE.............................
R9TA35_9EURY/4-377                 ........RVTVSVIKADVGSVGGHARPHPLMMQKCVERLKDGVRAGTVDDFYVTRVGDDINLYLTHTRGENNKDVH.GLCWDAFMDAT.KVAKEMKLYAAGQDLLTDAFSGNIRGAGPGAAEMEFKE......RGAEPIVFFMADKTEPSSYSFPLCKVFMDPFTTTGLVIDPRAHEGFKFEIVDVID.....SKKVIMSTPEETYDILTLLGDTTRYAIKRIWSK......SDDIgIGAVVSTEKLNISAGKYVGKDDPVCICRAQSGLPAVGEHLQPYM.FPA.LVAGWMRGSHYGAWYPCSVADSDP..........VFFDGPPRICAVGMHVS.NGKFQGledpnspvgvheP.LDYFAGSCWDEARRSAVKASMYMRRHGPFMPAVLGPEEMEYT.TRPAVLSKLKERME.............................
E6SJ08_THEM7/2-364                 .......d-VTVSVIKADVGSVAGHTRPSDELLEAVRQRVEAEKG-GLLLDARVFFCGDDISILMTHQRPPGDEAVH.RVAWEAFRAGT.AVAQRQGLYGAGQDLLKDAFSGNVRGMGPQVAELALRE......RPNEALMILAADKTEPGAFNLPLYLAFADPMYSPGLLLSEELHAGFRFVIMDVEHt..egDRLITLDAPERLYDIAALLRDTHRYVIAAIWSR.....kYPDE.QAAAVSTTRLRQIAGRYVGKDDPVAIVRVQKIFPATEEFGPPFA.LGA.FVAGDTRGSHNLPLLPVPVNTPA-..........STFFCHPMVAALGFSMR.DGQLTG............P.VDLFADPVWEPIRHRIVAKALGMRQQGFFQPAMLPISELEYG.GITARLRRLDAEF-r............................
D3E166_METRM/2-361                 ........KTTVSVIKADIGSVSGHCVSHPALMEKCDEVLANALETGILEDYYITRCGDDIDLIMTHRNGELNEEVH.KTAYDAFIQAT.EIARDLKLYGAGQDLLSDTFSGNVKGMGPGCAEMEFKE......RRSDPVIVYCMDKTEPGAFNLPIFKIFADPFNTAGLVIDPSLHDGFSFEVFDVME.....HKKVVLDCPEEMYDLLALIGSTGRYVIKRVFKK......-NGE.IAAAVSTDKLNMLAGEYVGKDDPVAIVRAQSGFPANGECVEPFA.FPH.MVSGWMRGSHNGPMMPTSQEEANP..........IRFDGPPRVVGLGFQVT.DAKLVG............P.VDLFDDPAFDETRRQSANIATYIRRHGPFEPHRLPSEEMEYT.SLPGVMEKLEPRFE.............................
A0A075WS01_9BACT/2-362             ........KLTLSVIKADIGGFVGHSSVHKDVLAKVKEVAEDGKDKGIIRDVSVLVCGDDIALVMTHTKGVDSSEVH.ELAWNAFKEGT.EVAKKLKMYGAGQDLLAEAFSGNVKGMGPGIAEMEFVE......RKSEPVIVFFADKTSPSAWNLPLYEMFADPMNTAGLVIDPSMHEGFIFDVMDAYT.....GMGIQLKTPEELYDLLVFIGATSRYVVRAVYRK......SDGE.IAAAASTQKLSFMAGRYVGKDDPVLIVRAQSGFPAVGEILEPFA.RPW.LVEGWMRGSHTGPLMPVAFKNAKP..........TRFDGPPRVIAAGYQIA.DGYLIG............P.SDLFDDPAFDHAREECNKMANILRRQGIFEPHRLPPEEMEYT.TLPKVLEKLKDRFK.............................
B4U833_HYDS0/2-361                 ........KITLSVIKADIGGYVGHSCTHPDVVKTTEEYVRKFVGN-LIIDLKVLTCGDDIALVMTHQHGVDSEKIH.KLAWDAFSAGT.EVAKKLKLYGAGQDLLTDAFSGNIKGLGPGVAEMEFEE......RPSEPVIVYFADKTSPSAWNLALYEMFASPMNTAGLVIDPKMHEGFTFTVLDVYT.....GKAVKLNTPSELYDLLALISSASKYVVKEVHRN......IDGE.IAAVASIQKLSLIAGQYVGKDDPVMIVRTQSGFPAVGEALEPFA.RPW.IVEGWMRGSHNGPIMPVGFEDATP..........SRFDGPPRVIAAGFQIA.NGMLVG............P.RDMFKDKAYDYARKVASDIANILRRQGIFEPHRLPSEEMEYT.TLPKVIEKLSSRF-f............................
A7I8R8_METB6/3-361                 ........KTTISVIKADVGSFPGHSRAHPKLLETAAQMLRAERGK-LLLDSFVTHCGDDLELVMTHSHGANSEAVH.RLAWNVFAECT.KVAKRFKLHGAGQDLLAEAFTGDIRELGPGVAEMEFEE......RESDPVLIFMADKTGPGAWNFYLYKIFADPFNTPGLVLDPALSGGFVFEVHDTVA.....KRMITFSCPEESYSLLAYIGSSSRYVIKYVFKR......-DGT.IVASTSTQRLNLTAGKYVGKDDPVMIVRAESGFPSMGEVLEPFT.VPV.LVAGWMRGSHNGPLLPVGLCDANC..........TRFDGPPRVVCFGFQVA.NGALVG............P.ADIFDDPAFDRVRARCNELADTIRAQGPFEPHRLSAGEMEYT.TLPAVEKELENRWK.............................
A0A0A7UZW4_9ARCH/2-359             ........KITVSVIKADVGGIGGHTRPSDNLIQAVRDTVNASS--DLLIDHYIGYCGDDVHIVMSHTHGVDNEKIH.KLAYDAFVAGT.AVAKNEGLYGAGQDLLKDSFSGNVKGMGPGVAELEFEE......RPNEAFTVFAADKTEPGCFNYPMYRLFVDALSNTGLIVNKSLAKGVDFHIMDVEE.....ATIAKLSLWQDKPVLEAALMYPGRYVISSITTK......-DGE.PIMDASTDRLHNIAGTYVGKDDPVCIVRTQKMFPATEEAGSVFN.NPH.YVAGNTRGSHNMPLMPVKLNSAA-..........TINFCIPIVQSLVFSMH.DGKFTG............P.FDGFSTPDWDYVREQATIKALAIRSQGFIHPATLVPDELEYAeGYKDVMTGLKEKM-v............................
T0LQP2_9EURY/2-366                 ........KVTLSHIKADIGSLPGHTTVHEDVVNQVRNHVKEHGK-GIISDFHISSIGDDIQITMAHNLGINSKEVH.GLAWDAFKDGT.EVAKKLGLYGAGQDLLKDSFSGNIKGMGPGVAEMEITP......RKSEPFIVYMMDKTEPGAFNYPIFKMFADPFNTPGLVIDNNMHEGFRFEVWDIIE.....GKNIYLDAPEEMYDIISLIGSKSRYVIKRVLTKet.hqkLPDE.NVAVITTDKLSFIAGEYVGKDDPAAIVRIQSGLPASGEAMEAFS.HPY.LVSGWMRGSFNGPLMPVGLKYSKM..........SRFDGPPKVGALGFVYK.DGKLSG............P.VDMFDDPAFDGARKLASDIADYIRRMGPFEPHRLPEEEMEYT.TMPKVMEKLKGRFQ.............................
N0BIT8_9EURY/4-368                 ........KITVSIIKADVGGLPGHVLVPDEIIEVAKQSLEEAKQSGDIIDYRVLNAGDDLDLIMTHREGVDSTKIH.RIAWETFEKAT.EKAKELKLYGAGQDLLADAFSGNVRGMGPGVAEMEFTE......RESEPVLAFLMDKTEPGAFNLPIFRMFADPFNTAGLVIDPSMHNGFVFEIWDIYE.....SKRVFMKTPEEIYDILALIGGKSRFVIKRVYPKeg..klPADE.PVAVISTEKLYKIAGEYVGKDDPVALVRAQSGLPAVGEVIEAFA.FPH.LVSGWMRGSHNGPIMPVPFRYSKC..........TRFDGPPRVIAAGFQLA.NGKLVG............P.VDLFDDPAFDYTRQKAMEVAEYMRRHGPFEPHRLPSEDMEYT.TLPGVLKKLKERFE.............................
U6EBE5_9EURY/2-362                 ........KTTISVIKADIGSVAGHGLAHPALLKKCEEILGKAKEEELLIDYYVTNCGDDTELIMTHRQGEENEEIH.EMAWTAFTEAT.AVAKELKLYGAGQDLLSDTFSGNIKGMGPGCAEMEFKE......RPSDPVVVFCCDKTEPGAFNLPLFKMFADPFTTAGLVIDPSLHNGFEFEVFDVME.....HKKVKLSCPDEMYDLLALLGTINRYVIKRIRRR......DDNE.IAAAISTERLNLMAGQYVGKDDPVAIVRAQSGFPAAGEVVEPFA.FPH.LVGGWMRGSHNGPLMPVGQKNAYP..........VRFDGPPRVMALGFQIA.EGKLVG............P.ADMFDDPAFDRSRDLASEVAEYMRRHGPFEPHRLPADEMEYT.TLPGVMEKLSSRFE.............................
I3TD51_THEC1/4-364                 ........KITLSVIKADVGSISGHYMPHPDQLAAATKVLSEAKQKGLLIDFYVTHVGDDIQLIMTHTKGPDHPDIH.GLAWDAFQAAT.KVAKELKLYAAGQDLLSDAFSGNVRGLGPGVAELEMEE......RKAEPVITFHADKTEPGAFNLPMYRIFADPFNTAGLVIDPRMHAGFVFEVFDVYE.....GKSVLLKTPEESYDLLALIGTPGRYIVRRVYRK......EDNL.LAAVVSVERLNLVAGQYVGKDDPVAIVRAQSGLPAVGEILEAFA.FPH.LVAGWMRGSHHGPLVPVSMRYARV..........TRFDGPPRVLALGWNIS.KGRLIG............P.ADLFDDVAFDETRRLALQIAEYMRRHGPFMPHRLGPEEMEYT.TLPEVLERLKNRF-v............................
D8K128_DEHLB/2-361                 ........KITLSVIKADIGGYVGHSDAHPECVCTADDALAKAKKSGLLIDYHTTKCGDDLQLIMTHQRGENNADIH.EMAWNTFVACT.EVAKKHKLYGAGQDLLTDAFSGNIKGMGPGAAEMEFEE......RTSEPVVVFMADKTSSGAWNLPLYKMFADPFNTIGLVIAENMHQGFKFEVHDVKE.....SKKITFKTPEEIYDMLVFIGAANRYPIKSVYTL......-SGE.IAASSSTQKLAFLAGRYVGKDDPVCIVRCQGSFPAVGEVLEPFA.KPY.LVEGWMRGSHYGPLMPVSVADSLP..........TRFDGPPRVTALGFQLA.EGRLVG............P.RDFFADVSYDQARQKANDMAYMMREHGPFEPHRLPLDEMEYT.TMPQVSRKLEGRFE.............................
O27721_METTH/2-362                 ........KTTISVIKADVGSVAGHAVAHEALKKKCDEILAGAKETGILEDYYITNCGDDIDLIMTHRNGEENEEVH.QTAWNAFREAT.DVARGLKLYGAGQDLLSDTFSGNIKGMGPGCAEMEFKE......RPSDPVIIFCCDKTEPGAFNLPLFRMFADPFNTAGLVIDPSLHNGYEFEVFDVVE.....HKKVTMACPDEMYDLLALLGSISRYVIKRIHRR......DDGE.IAASVSTERLNLMAGKYIGKDDPVAIVRAQSGFPAAGEVVEPFA.FPH.LVGGWMRGSHNGPLMPVAQRDATP..........VRFDGPPRVIALGFQVA.DCKLVG............P.VDMFDDPSFDRSRQLASEVAEYMRRHGPFEPHRLPSDEMEYT.SLPGVLEKLGDRFE.............................
D5U307_THEAM/4-364                 ........KITLSIIKADVGSIAGHHMPHPDQLAAATKILAEAKQKDIIIDFYVTHVGDDIQLIMTHRKGVDHPDIH.GLAWEAFKSAT.KVAKELKLYAAGQDLLSEAFSGNVRGMGPGVAELEMEE......REAEPVITFHADKTEPGAFNMPIYRIFADPFNTAGLVIDPKMHDGFIFEVYDVFE.....GRSVLMKTPEESYDVLALIGTPGRYIVRRVYRK......SDNL.LAAVVSVERLNLTAGRYVGKDDPVAIVRAQHGLPAVGEVLEPFS.FPH.LVAGWMRGSHHGPLMPVPMRYAKV..........TRFDGPPRIIALGWNIS.KGRLIG............P.VDLFDDVAFDETRRLAEMIAEYMRRHGPFMPHRLGPEEMEYT.TLPSVLEKLKDRF-v............................
E0SPU6_IGNAA/6-366                 ........KTTISVIKADIGSLAGHHVVHPDTMAAAAKVLAEAKSKGIIVDYYITHVGDDLELIMTHRKGVDAPEVH.EVAWNAFKEAA.KVAKELGLYAAGQDLLTDAFSGNVRGLGPSAAEMEFVE......RPAEPVIVFMADKTEPGAFNLPLFRVFGDPFNTAGLVIDPKLHDGFKFEVYDVIG.....GKYVIMNLPEEMYDLLALIGTPGRFVVRRVYRK......SDNE.IAAVVSVERLNLIAGQYVGKDDPVAIVRAQSGFPAVGEVIEAFA.FPH.LVAGWMRGSHFGPLMPVSQRNARC..........TRFDGPPRVVALGFQIK.NARLIG............P.ADLFDDPAYDETRRLAQTIAEYMRRHGPFMPHRLGPEEMEYT.TLPAVLQKLQNRF-v............................
A2ST38_METLZ/134-223               ..ivdgvl---------------------------------------------------------------------.-----------.--------------------------------------......-------------------------------------------------------.....---------------------------------......----.------------------------FLARAEGEFPSVAAFCERFA.---.-----RRGVNQQGVCPVSLCDSSN..........VRTTVIP-VVGLGFSLC.DGRLAG............P.VDLFDTPLFDAPRFRASD------------------------.--------------qhae.........................
Q8U359_PYRFU/6-372                 ........KITISVIKADVGGWPGHSRVHPALIERAKEVLSEAQKEGTLIDFYVTYAGDDLQLIMTHKKGVDSPEIH.GLAWEAFKKAT.EVAKELGLYGAGQDLLKDAFSGNVRGLGPSVAEMEITL......RKSEPIVTFHLDKTEPGAFNLPIFRMFADPFNTAGLVIDPKMHMGFRFEIWDILE.....HKRVIMNSPEEMYDILALIGAKSRYVIKRVYPKeg.hpiPKDE.PVAVVSTEKLYEVAGEYVGKDDPVAIVRAQSGLPALGEVLEPFA.FPH.LVSGWMRGSHNGPLMPVPLKYATP..........TRFDGPPRAVALGWQISpEGKLIG............P.VDLFDDPAFDWARQKALEITDYMRRHGPFEPHRLPLEEMEYT.TLPGVLEKLKDRFE.............................
Q8TWS8_METKA/8-371                 ........KVTVSVIKADVGGFPGHSEVHPDLLEACEGVLEDAVDE-VIIDYYVTRCGDDIDLIMTHTRGEDDEKVH.ELAWNAFQEAT.KVAEDLKLYGAGQDLLSDAFSGNVRGLGPGAAEMELVE......RPSEPIIVFCCDKTEPSAFNLPLFRIFADPNNTAGLVLDPSMHDGFEFEVHDVID.....QKKVILKCPEEMYDLLALIGQTQRYAIKRVYKKgd..gdEAER.IAAVTSTERLNLIAGEYVGKDDPVAIVRCQSGFPAVGEVLEPFT.FPH.LVAGWMRGSHNGPLMPVSEEEAHP..........TRFDGPPRIIALGFQLR.NGELVG............P.QDLFADPAFDRAREIANEVADYIRRHGPFQPHLLSEEELEYT.TLPDVLKKLEDRFE.............................
G4RLD7_THETK/2-372                 ........KTTISIIKADIGGWPGHAWVHPKMLELAAERLREAQRRGLIIDYFVYNVGDDISLLMTHTKGENHPEIH.GLAWETFKEVTeKIAKKFKLYGAGQDLLKDTFSGNIRGMGPQVAEMEIEE......RPSEPVITFAADKTEPGAFNLPMYKMFADPFNTAGLVIDPAMHEGFLYEVLDVYE.....HKVYLLKAPEDIYSLLGLIGTTGRYIVRRVYRR......SDGA.PAAAVSVERLNLIAGKYVGKDDPVAIVRAQHGMPAVGEVLEAFA.YPH.LVHGWMRGSHAGPLMPMKFYSIDAekriavgarmTRFDGPPKIGALGWQLH.DGYLEG............P.VDLFDDPAFDYTRQLAAMITDYIRRMGPFQPHRLPPEEMEYT.SLPKILAKIQ----sfs..........................
A3CVU2_METMJ/3-361                 ........KTTVSVIKADIGSFPGHSRTHPKILEVAARRLKEAEGS-ILIDSYVTHCGDDLELIMTHTKGEDNEEIH.KLAWDIFMECA.GLAKEMKLYGAGQDLLGDAFSGNVKGMGPGVAEMEFEE......RGSDPILVFMADKTEPGAWNYFLYKIFADPFSTSGLVIDPSLHDGFTFEVHDVIK.....KRKILFNTPEESYSLLAYIGAPSRYVIKYVWKR......-NGL.IGASTSTQRLNLMAGRYVGKDDPVMIVRAQSGFPAVGEVIDPFR.TPI.LVAGWMRGSHHGPFMPVGVCDANC..........TQFDGPPRVICLGFQVC.NGKLIG............P.ADMFDDPAYNRVRDQCCELSSLLRAHGPFEPHRLSLEEMEYT.TLPGVEKQFKDRWE.............................
I4BZA2_ANAMD/2-363                 ........RVTLTAIKADIGSIGGHIRPSASLLKEVERSLQPHLGS-DFIDFRLSYTGDDIAILMTHTHGTDNPLIH.QIAWDAFKAAA.DVAKKEGLYGAGQDLLKDAFSGNIRGLGPGIAEMEFEE......RKSEPFLLFAADKTDPGAFNLPLYLAFCDPMYCSGLLLSPNMFKGFKFEIMDVSYt..egDKVIALFAPEELYDIAALLRDPERYVVKAVYSR......TTGE.IAAVASTTRLHNIAGKYVGKDDPILLVRAQGSFPATGEILEPYA.LVP.YVGGFMRGSHQGPLMPVKRNSSV-..........SFFDGPPIVSCTAYCVK.DGKLSE............E.ADAFDHPFWDYVREIASKKAIELRRQGFYGNAMLPYGELEYG.GIVERLKALEGKFE.............................
A0B8T5_METTP/3-368                 ........KVTVSLIKADVGGWPGHASVHPALIDKAEEVLSEAKSAGTLIDFKVMACGDDLELLMTHRLGTDEAEIH.AIAWETFEKAT.AEAKSLKLYGAGQDLLCDAFSGNIRGMGPGVAEMQFTE......RDAEPLVAFMMDKTEPGAFNLPIFRMFADPFNTAGLVIDPSLHNGFIFEIWDILD.....HKKVFMSCPEEMYNILALIGAKSRYVIKRVYPKpg.gklPSEE.PVAVVSTEKLYQTAGTYVGKDDPVALVRAQSGLPALGEVLEPFA.LGH.LVSGWMRGSHNGPLMPCAFEDAHP..........TRFDGPPRVIAAGFQLC.NGLLIG............P.VDLFADVAFDLTRMRVLEITDYMRAHGPFEPHRLPLEDMEYT.TLPHVLKRLAERFE.............................
A5D3Q9_PELTS/4-361                 ........KVTVSVIKADIGGFVGHSSVHPELLETARGILAGS---PLLIDFHVTHVGDDINLIMTHDGGKDNGEIH.QLAWETFSSCT.KIAKKMKLYGAGQDLLADAFSGNIKGLGPGLAEMEFEE......RNSEPIIVFMADKTEPGAWNLPLYKMFADPFNTIGLVIDPKMHKGFLFEVHDLIE.....NKKITFSCPEELYDMLVFIGAPGRYCIKSVYHK......ETGE.IAATSSTQRLNLMAGRYVGKDDPVLIVRCQSGFPAVGEALEPFA.NPH.LVSGWMRGSHSGPLMPVSVAQSNP..........TRFDGPPRVVALGFQLS.DGKLHG............P.QDFFADPSYDLARQKANEIASYMRSMGPFEPHRLHLEEMEYT.TMPEVSKRIKDRFE.............................
M4YPD9_9EURY/4-377                 ........KVTVSIIKADIGSIAGHMTPHPSMMQAAKDILADKQKQGVIEDFYVTRVGDDINLYMTHYKGENNAEVH.GAAWDCFQEAT.KISRRMHLYAAGQDLLTDSFSGNVKGAGPGSAEMTFEE......RPAEPLVFFMADKTEPSAYSPILSRIFLDPFTTTGLVIDKRAKQGFDFEIRDVMD.....NKKVVMSSPEETLSILSLLGDTSRYAIKRVCSR......AGLG.PAAVVSTDKLNMTAGRYVGKDDPVCICRAQSGFPSVGEYTQVFAqYTW.LVAGWMRGSHIGAFYPCSPENSDP..........VYYDGPPRICCLGFQLV.NGHLQGlepegakngehiP.VDIFGSDTWDKARADAIRASKLMRSQGPFQPSILGAEEMEYT.SRPEVLKDLKTRF-v............................
A9BGJ9_PETMO/3-368                 ........KVSVSLIKADVGGIPGHSTVHPKLKEKASECLAEAKEKGLLVDYRVLHVGDDLQLLMSHRKGIDSEEIH.KLAWETFEAAT.KIAKELKLHGAGQDLLSDAFSGNIKGMGPGIAEMEFTE......RGSETLVAFMMDKTEPGSFNFPIYKIFADPFNTAGLIIDPLLIDGFIFEVWNIKE.....RKRIFLKCPEDLYLLLSLIGAKSKYVIKRVFPKds.splPKDE.PAVVVSTEKLFFIAEKYVGKDDPVALVRAQSGLPALGEVLEPFS.VPY.LVSGWMRGSHNGPLMPVSFKDAQC..........TRFDGPPRVIAAGFQIS.HGNFIG............P.IDLFDDPAFDLSRKKALELADYLRVQGPFEPHRLPPEEMEYT.TLPGVLKKLETRFE.............................
G0ECP9_PYRF1/25-385                ........KVTISVIKADIGSIAGHHKVHPDTMAAAARVLAEAKRKGVIIDFYVTHVGDDLQLIMTHRKGVDSPEIH.ELAWNAFKKAA.EVAKELGLYAAGQDLLSDAFSGNIRGLGPGVAEMEIVE......RPSEPIVIFMADKTEPGAFNLPLFRAFADPFTTAGLVIDPRMHDGFRFQILDLYE.....GRMIELNAPEEMYDILALIGDPTRYVIKRIFRK......TDGE.IAAVVSSERLNLIAGRYVGKDDPVAIARVQHGFPALGEILEPFA.FPH.LVPGWMRGSHWGPLMPVGLRDARC..........TRFDGPPRVIALGFQVT.KGRLIG............P.VDLFEDVAFDETRRLAQQIAEYMRRHGPFMPHRLHAEEMEYT.TLPDVLKKLEGRWK.............................
D3SN22_THEAH/2-362                 ........KITLSVIKADIGGYVGHSHAHPDVVEAVKEVGKEAVKKGTLIDCDVLVCGDDIALVMTHTHGVDSPVVH.GLAWEAFQRGT.QVAKKLKLYGAGQDLLSDAFSGNVKGMGPGVAEMEFEE......RPSEPVIVFFADKTAPSAWNLALYEMFADPMVCSGLVIDPKMHEGFTFEVLDTFT.....GKAVKLSTPSELYDLLALIGTVERYAVRSVWRN......SDGE.IAAVASTQRLSLIAGRYVGKDDPVLIVRAQSGFPAVGEILEPFA.RPW.IVEGWMRGSHNGPLMPVSFRHATP..........SRFDGPPRVIAAGYQLS.EGKLIG............P.RDLFDDPAFDNARQTAQMMADILRRQGIFEPHRLPSEEMEYT.TLPKILKKLEGRF-y............................
B1L6Y4_KORCO/3-363                 ........RTTVSVIKADIGGLAGHHIVHPKLKEIAASELAEAKSSRIIEDFYITSVGDDLQLIMTHRKGVDSSEVH.GLAWNTFKKCA.DAAKELGLYGAGQDLLKDAFSGNLRGMGPGVAEMEFEE......RPSDPIVVFMADKTEPGAFNLPIFKIFADPFNTAGLVIDPKLHSGFIFEIMDVIE.....SKVVELSSPEDMYDILSIIGTPSRYVIKRVFRK......VDRE.IAASISTTRLSLIAGKYVGKDDPVAIVRAQAGFPALGEILEPFS.FPF.LVAGWMRGSHAGPLMPVSERDARP..........TRFDGPPRIVALGFQVK.DSKLIG............P.SDLFSDVAFDETRRMANFIADYMRRHGPFMPHRLGPEEMEYT.TLPEVLKKLEGKF-r............................
Q8RCX0_CALS4/3-360                 ........KITLSVIKADIGGYVGHTDVHPDLLEIAKKMLKEKG--DMLIDFHVTRVGDDIQLIMTHREGVDSEKIH.KLAWDTFLACT.ERARELKLYGAGQDLLKDSFSGNIKGMGPGVAEMEFEE......RKSEPVVIFIADKTEPGAWNLPLYKMFADPFNTAGLIIDPSMHQGFKFEVYDMYE.....GKKIVFNTPEELYDMLVFIGATGRYCIRKVYTK......-NNE.IAAVSSTQRMNLMAGKYIGKDDPVLIVRCQNGLPAVGEVLEAFA.NPH.LVFGWMRGSHTGPMIPVSLEDAVP..........TRFDGPPRVCALGFQLK.EGKLIG............P.QDLFKDIAFDSARKKALEIADYMRTLGPFEPHRLPLQELEYT.TLPHLMEKLKDRWE.............................
Q6M0F4_METMP/4-363                 ........KVTLSVIKADVGGLCGHTLAPEELLDAAEYVLENALDE-TLIDYYVTNCGDDIDMIMTHNKGTDNEEVH.KLAWDALEAAT.EVAKELKLYGAGQDLLSTSFSGNVKGLGPGCAEMEFVE......RPSEPVVVFCCDKTDPAAFNLPFYRMFSDPFSTAGLVYDPSMTTGFRYEVLDVME.....HKRVFMDSPEETYSLLALIGNTEKYAVKRVYRR......KDNE.IAAVCSSEKLNMIAGEYVGKDDPVAIVRAQSGFPAVGEVLEGFA.NPH.LVAGWMRGCHFGPIMPVAEEDAMP..........ARFDGPARVMALGFQLS.HGRLVG............P.NDLFADKSFDKAREKALDMAEMMRSMGPFMPHRLPESMMEYT.SVPKVLAQLKDRF-l............................
B2A2Q6_NATTJ/2-363                 ........KITLSIIKADIGSIGGHLQPSDKLLNTIEEHLNSYGND-QFIDFYLGYTGDDVFILLTHRKGINNRQIH.QLAWDTFMVGT.ATAKKQRLYGAGQDLLSDSFSGNIKGLGPAVAEMEIEE......RENEPFLVFTADKTDPGAYNLPLYLSFCDPMHNPGLLLSPKIGDGFTFTVMDVSHt..eqDRIIQLNTPEDIYNLAALLRDNERFVVESIHSR......KSQE.QAAAASTTRLHHIAGKYVGKDDPVLLVRVQSHFPAVGEILSPYS.IGH.YVAGFMRGSHHGPLMPVKKNTTV-..........SYFDGPPMVNALAFCVS.EGKLTE............P.VDCFDQPFWDHIRDKVSRKSLDLREQGFSGPAMLPYSELEYG.GITHKMEELEKRF-d............................
F2NK02_DESAR/4-363                 ........KITLSVIKADVGGYVGHCAMHGELILEASRHLDDARSQGVLVDYHVTACGDDLELIMTHSHGVDNRDVH.HLAWEVFEACT.EVAKKLKLYGAGQDLLSHAFSGNVRGMGPGVAEMEFVE......RESEPIVIFMADKTSAGAWNLPLYKIFADPFNTAGLVIAPTLHAGFRYEVHDVKG.....HQKILFSTPEELYDLLVFIGATGRYLVKAVYTK......-DGE.IAAVSSTERLALIAGKYVGKDDPVCVVRCQGKFPAVGEVVEPFS.MPH.IVEGWMRGSHYGPLMPVPLSQARP..........TRFDGPPRVICLGFQLA.NGHLVG............P.CDIFDDPSFNEARRLCNVIADHLRRHGPFEPHRLPMDEMEYT.TLPQVMAKLQDRWQ.............................
M9SDA8_9EURY/4-376                 ........KVTVSIIKADIGSICGHMTPHPSMMAKAKEILTDKQKQGIIEDFYVTRVGDDINLYMTHYKGEGNKEVH.TAAWECFQEAT.KISKSMHLYAAGQDILTDAFSGNVKGAGPGSAEMTFEE......RPSEPLVFFMADKTEPSAYSPILTRIFLDPFTTTGLVIDKRAKMGFDVEIQDVMD.....HKKVVMSSPEETLSILSLLGDTSRYAIKRINSR......AGLG.PACVVSTDKLNMTAGRYVGKDDPVCICRAQSGFPSVGEYTQVFQ.NTW.LVAGWMRGSHIGAFYPCSPEDSNP..........VYYDGPPRICALGFQLC.EGHLQGlepqgvkggdhiP.VDIFGNNTWDNVRANAIKASRLMRAQGPFQPSILGAEEMEYT.SRPEVLEDLKKRFE.............................
Q6L0W0_PICTO/2-366                 ........KVTISHIKADIGSLPGHTTVFEPVVDAVEDYIKSNGKN-IISDYRISHIGDDIQITMVHNHGVDNPDVH.GLAWNAFKAGT.EVAKKYGLYGAGQDLLKDAFSGNVKGMGPGVAEMEITP......RKSEPFIVYMMDKTEPGSFNYPIYKMFGDPFNTPGLVIDPNMHAGFKFEVWDIIE.....GKRIMLSLPEQTYDLLALIGSKGRYVIKRVYTKee.htkLPAE.NVAVISTDKLSFIAGEYVGKDDPAAVVRIQSGLPAAGEALEPFA.NSY.LVSGWMRGSFNGPLMPVGIKNSRM..........TRFDGPPRVAALGFVLK.DGRLAG............P.VDMFDDIAFDYARTKALEMADYLRRMGVFEPHRLPDDDMEYT.ALPKILEKLSSKFE.............................
F0TA10_METLA/2-362                 ........KTTISVIKADVGSIAGHAKTHVALKNKCDEVLAKAKESELLVDYHITSCGDDIDLIMTHRNGEENEEVH.ELAWNAFLEAT.QVAKSLKLYGAGQDLLSDTFSGNIKGMGPGCAEMEFKE......RPSDPVIIFCCDKTEPGAFNMPLFKMFADPFNTAGLVIDPSLHGGYDFEIFDVIE.....HKKVTMSCPDEMYDALALLGSTGRYVIKHISRR......SDNE.IAASVSTERLNLMAGQYIGKDDPVAVVRAQSGFPAAGEVVEPFA.FPH.LVSGWMRGSHNGPLMPVAQRNANP..........VRFDGPPRVIALGFQIN.NSELVG............P.LDMFDDPAFDRSRDLASEVAEYMRRHGPFEPHRLPADEMEYT.SLPGVLKMLEDRME.............................
F9VMT6_SULTO/2-362                 ........KTTISVIKADIGSLAGHHIVHPDTMAAANKVLASAKEQGIILDYYITHVGDDLQLIMTHTRGELDTKVH.ETAWNAFKEAA.KVAKDLGLYAAGQDLLSDSFSGNVRGLGPGVAEMEIEE......RASEPIAIFMADKTEPGAYNLPLYKMFADPFNTPGLVIDPTMHGGFKFEVLDVYQ.....GEAVMLSAPQEIYDLLALIGTPARYVIRRVYRN......EDNL.LAAVVSIERLNLIAGKYVGKDDPVMIVRLQHGLPALGEALEAFA.FPH.LVPGWMRGSHYGPLMPVSQRDAKA..........TRFDGPPRLLGLGFNVK.NGRLVG............P.TDLFDDPAFDETRRLANIVADYMRRHGPFMPHRLEPTEMEYT.TLPLILEKLKDRFK.............................
#=GR F9VMT6_SULTO/2-362      SS    ........E---BBTTTTB--HHHHHHHHHHHHHHHHTTS-SEEEEEEETTEEEEEEEESS-TT-HHHHHHHHHHHH.HHHHHHHTT-B.TTTTT-TTSSSSSSTTTS-EEEEEEE---SS-EEEEEE......GGGHHHHHHHHH-TTT-THHHH-CCCTT-EEEEEEETTTTEEEEEETTTTHHHHH.....TTTEEEEEEEETTT--EEEEE----HCHHHTS-......EEEE.-STTS--HHHHHHTTSS--EEEETGGG-EEEE-EEE-STT-S--.GG-.-EEEEEEEEEETTEEEEEEESS-S..........HHHHHHHHTTTT-TTTB.-HHHHT............T.--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXX.............................
F4LWX0_TEPAE/4-362                 ........KITLSVIKADVGGFVGHGSVHPDMLKNAEEILEQQGKE-LLVDFFVTNVGDDINLILTHKEGINSEKVH.KLAWNTFLSCT.EVAKSLKMYGAGQDLLSDAFSGNIKGMGPGIAEMEFEE......RPSEPVIIFMADKTEPGAWNLPLYKIFADPFNTIGLVIDPKMHSGFCFEVLDLVE.....DKKVTFSCPEELYDLLIFLGASNRYVVKSVYTK......-NKE.IAAVSSTQKMNQMAGRYVGKDDPVLIVRCQSGLPAVGEVLEPFA.NPH.LVTGWMRGSHYGPLIPVSQKQAVP..........TRFDGPPRAIAMGFQLA.NGRLIG............P.QDLFADVAFDRARQKALKAADYIRQMGPFEPHRLPLDEMEYT.TMPQVMEKLKNRFK.............................
H5X3U9_9PSEU/1-361                 .......m-TTLSIIKADTGGFVGHSAVHPDLLATAQEAVRRAVGDGLLLDAHVASCGDDVSLIMTHEHGADSERVH.SFAWDTFQQTT.EVAKRLGLYGAGQDLLSDAFSGNLKGMGPGYAELEFTE......RPSEPVICFLADKTEPGAWNLALYKMFADPFNTAGLVIDEKMHAGFRFEVYDLFE.....EKRITFDCPEELYDMLMFIGAPARYVVHAVQSR......NLTE.QAAATSTQRLSLIAGKYVGKDDPVMIVRCQSGLPAVGEVLEPFS.FPY.TVGGAMRGSHHAPLLPVSIPDAHT..........ARFDGPPRVVALGFQVT.DGRLVG............P.RDMFADPSFDSARQQANTAMDYLRRHGPFEPHRLPLEDLEYT.TMRALEARIAQRWQ.............................
E1QTV0_VULDI/2-371                 ........KVTVSIIKADIGGLPGHAWVHPKILEFAADRLREEQKRGLIIDYFVYNVGDDMSLLMTHTKGENNPDIH.GLAWSIFKEATeNIAKKVKLYGAGQDLLKDTFSGNIRGLGPQVAEMELEE......RPSEPLVVFAADKTEPGAFNLPFYRIFADPFNTAGLVIDPAMHQGFRFEILDVYE.....GKVYLLDAPENSYDILGLIGTPGRYIIRRIYRK......ADLI.QASVTSVERLNLIAGRYVGKDDPVAMVRAQHGLPAVGEILEAFA.YPH.LVEGWMRGSHVGPLMPTKMISIDQekkialgpkmTRFDGPPKVISLGFQLH.DGYLEG............P.VDLFDDPAFDYSRQLAAQITDYIRRMGPVMPHRLPPEEMEYT.TLPQILSKLK----pi...........................
D2RDW4_ARCPA/4-369                 ........KITVSVIKADIGSVAGHSTVPDEIKALAEKKLNEAKEKGIIIDFRVFNAGDDLELVMTHRKGVDSEEIH.GLAWETFKACA.EKAKELKLYAAGQDLLKEAFSGNVRGLGPGVAEMEFTE......RPAEPIIVFMMDKTEPGAFNLPIFRMFADPFNTAGLVIDPSMHQGFRFEVWDIKE.....HKRVMLSTPEEMYDLLALIGSKGRYVIKRVYPKeg.gklPADE.PVAVVSTEKLFEIAGEYVGKDDPVAIVRAQSGLPAVGEVLEAFA.FPH.LVSGWMRGSHNGPLMPVPFRYSKC..........TRFDGPPRVIAAGFQLC.NGKLIG............P.VDMFDDPAFDYTRQKAMEICDYIRRHGPFEPHRLPHEEMEYT.TLPKVLKKLEARFE.............................
A0RV30_CENSY/131-487               ........RITVSAIKADVGGIGGHTLPSSGLLDAVRRKVSSS---SLLIDHYIGYCGDDVHIVMTHTRGTDNSDIH.KLAWDAFMEGT.RVAKEEGLYGAGQDLLRDSFSGNVKGMGPGVAELEFEE......RANEAFTVFAADKTEPGAFNYPFYRMFVDSLSNTGLIVNKSLAEGVVINIMDVSK.....ARTARLVLWEDKPTIEAALMYPGRFVVSSVETR......-DGE.PIASASTDRLHNIAGTYVGKDDPICLVRTQKRFPATEEAGSCFN.NPH.YVAGNTRGSHHMPLMPVRLNSPA-..........SINFCIPIVEALVFSMH.EGRLTG............P.FDGFSTPDWDDVRRTATRRAHAMRRQGFVHPATLVPDELEYAeGYRSRMDVLDSKM-v............................
A0A086YTL3_9FIRM/4-361             ........KITLSVIKADVGSYVGHSNVYPALLEKARGMVSGS---PLLIDSYVTHVGDDINLIMTHEFERNNGEIH.QLAWDTFLACT.EVAKKLKLYGAGQDLLSDAFSGNIKGLGPGVAEMTIEE......RRSEPIIVFMADKTEPGAWNLPLYKIFADPFNTSGLVIDPSMHEGFLFEVRDLIE.....NKKVTFSAPEEIYDLLVFIGTRGRYCIKSIFHK......QTGE.IAAISSTQKLNLLAGRYVGKDDPVLIVRCQSGMPAVGEALEPFA.NPQ.LVSGWMRGSHCGPLMPVSVEQSTP..........TRFDGPPRVIALGFQLC.EGKLIG............P.QDFFKDVAFDQARQTANFIANYMRSQGPFEPHRLPENEMEYT.TMPQVIKKLKDRFE.............................
A0A060HR72_9ARCH/2-361             ........RITISAIKADIGGIGGHTRPSDELVDAVKSFVAKNSK-GMLIDHYIGFSGDDIHIIMTHTLGVDNEKIH.KLAWDAFTEGT.KVAKEQGLYGAGQDLLKDSFSGNVKGMGPGVAEIEMEE......RPSEVFCIFAADKTEPGAYNFPLWRMFVDARSNTGLLINERLAEGVVFRIMDVMS.....GKVADLKMWQDKAELEAALMYPGRYVVSAVFSA......DMSE.QIVSASTDRLHNIAGTYVGKDDPIMIVRTQKNFPATEEAGSAFN.DPH.YVAGNTRGSHHMPLQPVRLNSAA-..........SLNYSIPIVSCLLFSMH.NGKLTG............P.HDGFGTVDWDLQRMWAAERAMIMRNQGFIHPATLIPEELEYNkGYQARMSKLESKFR.............................
Q2LQY4_SYNAS/2-363                 ........KTTLSIIKADVGSVGGHIRPSERLIQEVKNFVVEKG-QGVISDFFISHTGDDIAILLSHSRGKGDGIIH.QLAWDAFVTGT.KVAKEQGLYGAGQDLLKDSFSGNVRGMGPAVAEMEFEE......RPNEPFLFFAADKTDPGAYNLPLYLAFTDPMYNSGLILSPTMNKGFRFVIMDVEYt..egDRVIELNAPEDIYDIAALLRDNERFVVEAIYSR......STGD.IAVSVSTTRLHNIAGKYTGKDDPVMLVRVQGTFPATGEVLAPFN.IGH.FVAGFMRGSHTGPLMPVKMNSGI-..........SYFDGPPIICCLAFCVH.KGKFTE............P.ADAFDHPYWDYIRNNVARKATEMRAQGFSGAAMLPYSELEYG.GIVEKMKILDERFK.............................
A0A0A7GK02_9EURY/1-363             ........---MSLIKADVGGLPGHVTVADELIEKAQETLSIAKDSGLIIDFRVFRAGDDLELVMTHRKGVDSEEIH.KLAWETFEKAT.AIAKELKLYGAGQDLLSDAFSGNVRGMGPGVAEMEFTE......RGAEPVIAFMMDKTEPGAFNLPIFRMFADPFNTAGLVIDPNLHNGFVFEIWDIYE.....HKRVLMSSPEEMYDILALIGAKSRFVIKRVFPKeg.gklPADE.PVAVISTEKLYQIAGEYVGKDDPVALVRAQSGLPAVGEVLEPFA.FPH.LVSGWMRGSHNGPLMPVPFHYSKC..........TRFDGPPRVIAAGFQLA.NGKLVG............P.VDLFDDPAYDYTRQKAVEIAEYMRRHGPFEPHRLPMEDMEYT.TLPKVMDRLKDRFE.............................
T0LKG6_9EURY/2-366                 ........KITVSLIKADVGGLAGHSRVHPQLKDEARLVLEQAKNDSKIIDYHVTSVGDDLELIMTHKNGVDSKYIH.GLAWDAFIKAT.ETAKKLKLYGAGQDLLKDSFSGNLKGMGPGVAELEFEE......RKSEPIVAFMMDKTEPGAFNLPIYKIFADPFNTPGLVIDPHMHDGFTFEIWDTIE.....HKKVFLKTPEETYDILALIGSKERYVIKRVFPAks..tgMSNE.AIAVVSTDILHEIAGKYVGKDDPVAMVRGQAGLPAMGEILEPFT.FPH.LVSGWMRGSHNGPIMPVSVADATP..........SRFDGPPRVIGLGFQLA.EGKLVG............P.ADLLADKAFDGARQMAIQIADYMRRNGPFEPHRLPEPEMEYT.MLPSIQKKLKSKM-v............................
J1APM5_9EURY/1-260                 .......m-ITLTVLTADFGGFPAGLRAHPLLVEKAAKLLRAEHGK-RIIDSFTTRAGGRLASVFTSA-GEDGA-V-.CVVDDLCAACR.IVSGEIGLSGSG---------------GAETVSLTFEE......RPGEAVLVFLSAGAAPSVWGMPLCRIFADPFTSPALVREPLMCGGFSFTCDD---.....--GSVFSTPAEICGLLRHLE-GGRLPVR-VERQ......-DRL.PAAA---------AGR---GPDPALIVRAGKGLPVVGEAITAAA.G--.-----------NGLMAVSLCDMTP..........V----RPKTACLGFSIH.DGMLIG............P.ADLYDDPVF---------------------------------.--------------gr...........................
R9SJ68_9EURY/2-361                 ........KTTISVIKADIGSVSGHCVSHPALMEKCDEVLNNALEESILDDYYISRCGDDIDLIMSHRNGELNEEVH.RVAYNAFMEAT.KIARENKLYGAGQDLLSDTFSGNIKGMGPGIAEMEFKE......RPSDPVIIYCCDKTEPGAFNLPLYKMFADPFNTAGLVIDPKLHDGFKFEVYDVMD.....NKKVILNCPEELYDLLALIGSTGRYVIKRVWKK......-NGE.IAASVSTERLNLMAGEYVGKDDPAAIVRAQSGFPAAGECNEAFA.FPH.MVSGWMRGSHNGPLMPVSEEYANP..........VRFDGPPRVIGLGFQVA.DAKLIG............P.VDIFDDPAYDETRQLASRAASYIRRHGPFEPHRLPSEDMEYT.SLPGVMEKLEPRFE.............................
F4B800_ACIHW/5-365                 ........KTTISVIKADIGSLAGHHVVHPDTMAAANKVLAEAKKNGVIIDYYITNVGDDMELIMTHNRGELDTKVH.ETAWDAFKEAT.KVAKDLGLYAAGQDLLSDTFSGNLKGMGPGIAEMEIEE......RPAEPIAIFMADKTEPGAFNYPQYKMFADPFNTAGLVIDPTMHEGYKFEILDVYA.....GESVTLNAPEEIYDILALIGTPSQYVIRRVYRK......ADNM.IASVTSIERLNLLAGKYVGKDDPVMIVRVQHGFPALGEVLEAFS.FPY.LVPGWMRGSHYGPLMPVSQRDARA..........TRFDGPPRLIGLGFNVK.NGRLVG............P.SDLFDDPAFDETRRLAEQIADYMRRHGPFMPHRLEPTEMEYT.TLPLIQQKLKARFK.............................
F6D4D1_METPW/2-362                 ........KTTVSVIKADVGSVAGHAVTHGALLKKCDEILAKAKEEELLTDYYITNCGDDIDLIMTHKNGEENEEVH.ELAFNAFMEAT.KVAKSLKLYGAGQDILSDTFSGNIKGMGPGCAEMEFKE......RPSDPVFVFCCDKTEPGAFNLPVFRMFADPFNTAGLVIDPSLHGGYDFEIFDVIE.....HRKVTMSCPDEMYDALALLGSIGRYIIKHVTRR......SDGE.IAASISTERLNLMAGKYIGKDDPVAIVRSQSGFPAAGEVVEPFA.FPH.LVGGWMRGSHNGPLMPVSQAQAHP..........VRFDGPPRIISLGFQVS.DARLIG............P.LDMFDDPAFDNSRKTASDVADYMRRHGPFEPHRLPADEMEYT.SLPGVLEKLEDRFE.............................
B8D642_DESK1/4-364                 ........KITLSVIKADLGSIAGHHMPHPDQLAAVTKMLAEAKQKGLIVDFYVTHVGDDIQLIMTHTKGPDHPDIH.GLAWDAFKAAT.KVARELKLYAAGQDLLSEAFSGNVKGLGPGVAELEMEE......REAEPVITFHADKTEPGAFNLPLFRVFADPFNTAGLVIDPKMHDGFVFEVYDVFE.....GRSVLLKSPEEMYDILALIGTPGRYIVRRVYRK......SDNL.LAAVVSVERLNLIAGRYVGKDDPVAIVRAQHGLPAVGEVLEAFS.FPH.LVAGWMRGSHHGPLMPVPMRYARV..........TRFDGPPRVIALGWNIS.NGKLIG............P.ADLFDDVAFDETRRLAQFIAEYMRRHGPFMPHRLGPEEMEYT.TLPLVLEKLKDRF-v............................
T0NFL9_9EURY/2-366                 ........KTTISHIKADIGSLPGHTVVYQPVVDAVENYVKNNSG-GLISDFHISHIGDDIQITMVHTRGADNEEIH.GLAWNAFKAGT.EVAKKIGLYGAGQDLLKDAFSGNIKGMGPGVAELEITP......RKSEPFIVYMMDKTEPGAFNYPIYKMFGDPFNTPGLVIDPNMHMGFKFEVWDIYN.....GKKIYLSLPEDTYDLLAFIGSKSKYVIKRVYTKdt.htkLPDE.NVAVITTDKLSFIAGEYVGKDDPAGIVRIQSGLPASGEALEPFA.NSY.LVSGWMRGSFNGPMMPVGMNNAQM..........TRFDGPPRVMALGFVMK.DGKLAG............P.VDMFRDVAFDHARTEALDMANYIRRMGVFEPHRLPDEEMEYT.ALPKILEKLAPKFQ.............................
A5UKU2_METS3/2-361                 ........KTTVSVIKADIGSVSGHCVAHPDLMDICDEVLAEALETNILTDYYISRCGDDIDLIMTHRNGEENEEVH.ETAYNAFMKAT.ERARELKLYGAGQDLLSDTFSGNIKGMGPGVAEMEFKE......RPSDPVLVYCCDKTEPGAFNLPIFKMFADPFNTAGLVIDPSLHDGFKFEVFDVIE.....HRKVILNCPEEMYDLLALIGSTGRYVIKRVWKK......-NGE.IAAAISTERLNLMAGEYVGKDDPAAIVRAQSGFPANGECVEPFA.FPH.MVSGWMRGSHNGPMMPVSERDANP..........IRFDGPPRVIGLGFQVS.DAKLIG............P.VDLFDDPAFDPTREESARIATYIRRHGPFEPHRLPAEEMEYT.SLPGVMAKLEDRFE.............................
#=GC SS_cons                       ........E---BBTTTTB--HHHHHHHHHHHHHHHHTTS-SEEEEEEETTEEEEEEEESS-TT-HHHHHHHHHHHH.HHHHHHHTT-B.TTTTT-TTSSSSSSTTTS-EEEEEEE---SS-EEEEEE......GGGHHHHHHHHH-TTT-THHHH-CCCTT-EEEEEEETTTTEEEEEETTTTHHHHH.....TTTEEEEEEEETTT--EEEEE----HCHHHTS-......EEEE.-STTS--HHHHHHTTSS--EEEETGGG-EEEE-EEE-STT-S--.GG-.-EEEEEEEEEETTEEEEEEESS-S..........HHHHHHHHTTTT-TTTB.-HHHHT............T.--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXXXXXX.............................
#=GC seq_cons                      ........KlTlSVIKADlGuhsGHstsHPcllptscchLpcutppulllDaaVopsGDDlpLlMTHp+GhDsp-lH.pLAWcsFppuT.cVAKcL+LYGAGQDLLsDuFSGNl+GhGPGlAEMEFpE......R.SEPlllFhuDKTEPGAaNLPLY+hFADPFNTuGLVIDPpMHpGFpFEVhDlh-.....pKplhhssPEEhYDlLALIGssuRYlIK+Vap+.......ssE..AAlsST-+LshlAG+YVGKDDPVsIVRsQSGhPAlGElLEPFu.hPH.LVuGWMRGSHpGPLMPVuhcsAps..........oRFDGPPRVlALGFQls.cG+LlG............P.sDhF-DPAFDpsRppAtclA-YhRRpGPFpPHRLP.-EMEYT.TLPpVhcKLcsRF..............................
//
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