GenomeNet

Database: Pfam
Entry: FCP1_C
LinkDB: FCP1_C
Original site: FCP1_C 
#=GF ID   FCP1_C
#=GF AC   PF09309.6
#=GF DE   FCP1, C-terminal
#=GF AU   Mistry J, Sammut SJ
#=GF SE   pdb_1onv
#=GF GA   22.70 22.70;
#=GF TC   24.40 23.30;
#=GF NC   22.60 22.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12732728
#=GF RT   NMR structure of a complex containing the TFIIF subunit RAP74
#=GF RT   and the RNA polymerase II carboxyl-terminal domain phosphatase
#=GF RT   FCP1. 
#=GF RA   Nguyen BD, Abbott KL, Potempa K, Kobor MS, Archambault J,
#=GF RA   Greenblatt J, Legault P, Omichinski JG; 
#=GF RL   Proc Natl Acad Sci U S A. 2003;100:5688-5693.
#=GF DR   INTERPRO; IPR015388;
#=GF CC   The C-terminal domain of FCP-1 is required for interaction with
#=GF CC   the carboxy terminal domain of RAP74. Interaction relies
#=GF CC   extensively on van der Waals contacts between hydrophobic
#=GF CC   residues situated within alpha-helices in both domains [1].
#=GF SQ   94
#=GS G1RAC3_NOMLE/717-961   AC G1RAC3.1
#=GS G3WH30_SARHA/653-806   AC G3WH30.1
#=GS F1RWS7_PIG/402-651     AC F1RWS7.1
#=GS Q3U0S4_MOUSE/706-960   AC Q3U0S4.1
#=GS E7FFL3_DANRE/676-947   AC E7FFL3.1
#=GS D3ZMS2_RAT/715-969     AC D3ZMS2.1
#=GS F6WRF7_HORSE/589-842   AC F6WRF7.1
#=GS H2NWM9_PONAB/711-956   AC H2NWM9.1
#=GS F7F664_ORNAN/678-945   AC F7F664.2
#=GS F7B931_MONDO/633-889   AC F7B931.2
#=GS CTDP1_MOUSE/706-960    AC Q7TSG2.1
#=GS G6DTG6_DANPL/536-680   AC G6DTG6.1
#=GS H2U7R4_TAKRU/680-938   AC H2U7R4.1
#=GS V8P7X6_OPHHA/551-806   AC V8P7X6.1
#=GS H0UYY7_CAVPO/713-966   AC H0UYY7.1
#=GS Q98SN2_XENLA/721-980   AC Q98SN2.1
#=GS G1LUZ4_AILME/646-841   AC G1LUZ4.1
#=GS G3P1I5_GASAC/706-847   AC G3P1I5.1
#=GS W5L335_ASTMX/692-972   AC W5L335.1
#=GS Q569U3_XENLA/718-979   AC Q569U3.1
#=GS H2QER0_PANTR/820-925   AC H2QER0.1
#=GS K7FCQ3_PELSI/605-759   AC K7FCQ3.1
#=GS U3J536_ANAPL/606-870   AC U3J536.1
#=GS G7PWA5_MACFA/616-861   AC G7PWA5.1
#=GS S9WY50_9CETA/506-555   AC S9WY50.1
#=GS U3DU16_CALJA/716-961   AC U3DU16.1
#=GS Q4S035_TETNG/691-979   AC Q4S035.1
#=GS Q9PT70_XENLA/606-867   AC Q9PT70.1
#=GS C3YBP7_BRAFL/294-496   AC C3YBP7.1
#=GS F7F659_ORNAN/686-945   AC F7F659.1
#=GS Q641F9_XENLA/717-977   AC Q641F9.1
#=GS G5AP10_HETGA/714-963   AC G5AP10.1
#=GS T1IZ83_STRMM/580-734   AC T1IZ83.1
#=GS G3WH29_SARHA/661-814   AC G3WH29.1
#=GS L8Y685_TUPCH/797-876   AC L8Y685.1
#=GS G7NKA9_MACMU/616-861   AC G7NKA9.1
#=GS T1K4P5_TETUR/462-572   AC T1K4P5.1
#=GS G1PIU1_MYOLU/585-836   AC G1PIU1.1
#=GS F8W4I4_DANRE/676-947   AC F8W4I4.1
#=GS K9IV94_DESRO/594-845   AC K9IV94.1
#=GS Q6DRN5_DANRE/676-947   AC Q6DRN5.1
#=GS H9J3M1_BOMMO/547-688   AC H9J3M1.1
#=GS G3TL65_LOXAF/666-926   AC G3TL65.1
#=GS R0LIA4_ANAPL/630-788   AC R0LIA4.1
#=GS U3KFV6_FICAL/613-872   AC U3KFV6.1
#=GS H2ZXN9_LATCH/586-846   AC H2ZXN9.2
#=GS F7G7V6_CALJA/716-965   AC F7G7V6.1
#=GS K6ZJ11_PANTR/716-961   AC K6ZJ11.1
#=GS Q4STX2_TETNG/1-59      AC Q4STX2.1
#=GS H0Z8E0_TAEGU/600-859   AC H0Z8E0.1
#=GS K7CNU2_PANTR/716-961   AC K7CNU2.1
#=GS H2MEM1_ORYLA/697-843   AC H2MEM1.1
#=GS F7E4V3_MACMU/721-966   AC F7E4V3.1
#=GS H2QER0_PANTR/716-824   AC H2QER0.1
#=GS M1EJH0_MUSPF/575-819   AC M1EJH0.1
#=GS I3MHY0_SPETR/624-878   AC I3MHY0.1
#=GS K7EJD2_HUMAN/648-794   AC K7EJD2.1
#=GS U3B9J0_CALJA/716-839   AC U3B9J0.1
#=GS W4Z059_STRPU/503-672   AC W4Z059.1
#=GS G1SKL9_RABIT/585-838   AC G1SKL9.2
#=GS F7HRQ5_MACMU/721-843   AC F7HRQ5.1
#=GS G3HCQ6_CRIGR/594-848   AC G3HCQ6.1
#=GS H2U7R2_TAKRU/691-964   AC H2U7R2.1
#=GS G1MTK5_MELGA/626-779   AC G1MTK5.1
#=GS S4NHB6_9NEOP/1-125     AC S4NHB6.1
#=GS G3R674_GORGO/683-928   AC G3R674.1
#=GS F6PKT6_CIOIN/662-822   AC F6PKT6.2
#=GS L5KKR6_PTEAL/673-918   AC L5KKR6.1
#=GS M3YYY9_MUSPF/617-759   AC M3YYY9.1
#=GS E0CZ13_MOUSE/4-172     AC E0CZ13.1
#=GS M3VV05_FELCA/623-865   AC M3VV05.1
#=GS E2R1Y2_CANFA/692-933   AC E2R1Y2.2
#=GS U3CFF3_CALJA/716-838   AC U3CFF3.1
#=GS M3ZU95_XIPMA/716-1000  AC M3ZU95.1
#=GS H0XQT5_OTOGA/698-867   AC H0XQT5.1
#=GS V9KFN1_CALMI/514-793   AC V9KFN1.1
#=GS B7PHL5_IXOSC/100-183   AC B7PHL5.1
#=GS B2L510_XENBO/6-35      AC B2L510.1
#=GS F1NZN8_CHICK/678-940   AC F1NZN8.2
#=GS F7B1B3_XENTR/717-978   AC F7B1B3.1
#=GS S9WY50_9CETA/419-509   AC S9WY50.1
#=GS H2U7R3_TAKRU/691-956   AC H2U7R3.1
#=GS L5M062_MYODS/573-823   AC L5M062.1
#=GS G1KVK5_ANOCA/709-958   AC G1KVK5.1
#=GS G1RAC4_NOMLE/717-843   AC G1RAC4.2
#=GS H3D945_TETNG/652-908   AC H3D945.1
#=GS W5MPI5_LEPOC/712-875   AC W5MPI5.1
#=GS D6WSR3_TRICA/594-758   AC D6WSR3.1
#=GS L7LWR1_9ACAR/100-214   AC L7LWR1.1
#=GS CTDP1_HUMAN/716-961    AC Q9Y5B0.3
#=GS CTDP1_HUMAN/716-961    DR PDB; 1ONV B; 941-961;
#=GS CTDP1_HUMAN/716-961    DR PDB; 1J2X B; 944-961;
#=GS W5P213_SHEEP/631-874   AC W5P213.1
#=GS M7BHU1_CHEMY/629-887   AC M7BHU1.1
#=GS L8Y685_TUPCH/539-743   AC L8Y685.1
#=GS I3JLE3_ORENI/712-999   AC I3JLE3.1
G1RAC3_NOMLE/717-961              .......................................ERWDKVEEQLFPLRDDHTKAQ.RE..NSPTAFPDRE..G.VPLTALFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPPSS....LPIRQEP.SSFRAVPPPQP...QMFGEE..........-LP.D.AQD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KRRP.EEQEEE-..---.PQP........RKP---GTRREQ...TLG.................APASSERSAAGGQ.gPR.--VRGL......RGEXXXX................xXXXRESS.NED-EGS.SSEADEMAKALEAELKDLM..............................
G3WH30_SARHA/653-806              .......................................ERWDKVEEQLFPLKEDYIKTQ.RE..NSPATFPDIQ..S.AFPTALFHPTPIHPKC..QPGPEVRIYDSNTGKLI.RKGTQNTGQSLY..iQSPASPVT....LPVHGEH.SSFRVVQPHQQ...QMFGEE..........-LP.T.SQDeDEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKE----------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------..............................
F1RWS7_PIG/402-651                .......................................ERWDKVEEQLFPLQDDHGRGQ.RE..DCPAAFPDRQ..G.VLPTTLCHPTPVHPRA..PPGPEVRIYDASTGKLI.RKGAVG------...--PGPPGS....LPVHTEL.SSFRAVQPHQQ...QMFGED..........-SP.D.NQD.GEQPGPSR...RKRQPS...MSEAM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKP.DDPEEP-..--G.PKS........GELGALRAQRGH...TLK.................SAPPSERHAADGR.gPR.GHKRKL......NDEDAAS.................ESSGASS.CEDEEGG.SSEADEMAAALEAELGDLM..............................
Q3U0S4_MOUSE/706-960              .......................................ERWDKVEEQLFPLIDDDTRTH.RD..NSPAVFPDRH..S.VLPTALFHPTPIHSKA..HPGPEVRIYDSNTGKLI.RMGPQGS-----...-APAPSSA....PLNHGEP.SSFRAVQPHQQ...QMFGEE..........-LP.E.SQD.GEQPGPAR...RKRQPS...MSEAM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDIE.KKKP.EDQDNEQ..ERA.PKP........RKPRAPGIRREQ...PVG.................LPSSGERSTPGMR.gPR.GHKRKL......NEEDAAS.................ESSGESS.NDDEEGS.SSEADEMAAALEAELNDLM..............................
E7FFL3_DANRE/676-947              .......................................ERWERVEEQLFPLKEDYNKSH.RS..NSPGAFLDIH..G.SAPRPPFQAPQVQPKP..LPAPEMRTYDPVTGKLI.RRGPQASRPPSY...LHSHPSSS....MSAKGDL.SNLRSAQGSQQ...---TDE..........PAG.S.SPD.DEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLDSMDKEVDDILGEESDnESEGKgKAGR.IEEEEEE..-VR.PHTs......kQKPPATDHIPPL...--Aavv..........eetsQTSTSEVCVTENV..LR.GHKRKLeearedEDKDEED.................GDSSKDS.NEDDEGS.SSEADEMAAALEAELNDFI..............................
D3ZMS2_RAT/715-969                .......................................ERWDKVEEQLFPLMDEDTRTH.RD..NSPAVFPDRH..S.MLPTALFHPTPIHSKA..HPGPEVRIYDSNTGKLI.RMGTQGP-----...-APALSSA....PLIHGEP.SSFRAVQPHQQ...QMFGEE..........-LP.E.SQD.GEQPGPAR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSESE.KKKA.EDQDSEQ..ERA.RKP........RKPRAPGTRREQ...PAG.................LPSPGERSAAGTR.aPR.GHKRKL......NEEDAAS.................ESSGESS.NDDEEGS.SSEADEMAAALEAELNDLM..............................
F6WRF7_HORSE/589-842              .......................................ERWDKVEEQLFPLRDDYGRAQ.RE..ESPAAFPDRQ..S.ALPAAVFHPTPVHPRA..QAGPEVRIYDANTGKLI.RKGTAG------...--PGPPGS....LPVHVEH.SSFRVVQPHQQ...QMFGEE..........-LP.D.NQD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKP.EEQEEEE..QEGaPQP........REPKAPGAHRGH...TLE.................STSSSERSAADGR.gPR.GHKRKL......NEGDAAS.................ESSGESS.CEDEEGS.SSEADEMAAALEAELSDLM..............................
H2NWM9_PONAB/711-956              .......................................ERWDKVEEQLFPLRDDHTKAQ.RE..NSLAAFPDQE..G.VPPTALFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPSSS....LPIRQEP.SSFRAVPPPQP...QMFGEE..........-LP.D.AQD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KRRP.EEQEEE-..---.PQP........RKP---GTRRER...TLG.................APASSERSAAGGR.gPR.GHKRKL......NEEDAAS.................ESSRESS.NED-EGS.SSEADEMAKALEAELNDLM..............................
F7F664_ORNAN/678-945              .......................................ERWDKVEEQLFPLKEDYVKTQ.RE..NSPATFPDTQ..S.AFQTALFHPTPIHPKC..QPGPEVRIYDPNTGKLI.RKGSQNPGQSLY..iQPPAPPLT....LPVHGEH.SSFRVVQPHQQ...QLFGEE..........ELP.A.NQD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.ESDSA.KKKP.EEEEEEE..DKE.KEEe.....rkEEAEATTAATME...EEEk...............pSTSATETLETKTE..PRpGHKRKR......PEADVAS.................ESSKESS.NEDEEGS.SSEADEMAAALEAELNDFM..............................
F7B931_MONDO/633-889              .......................................ERWDKVEEQLFPLKEDYIKTQ.RE..NSPATFPDIQ..S.AFPTALFHPTPIHPKC..QPGPEVRIYDSNTGKLI.RKGSQNSGQSLY..iQSPASPVT....LPVHGEH.SSFRVVQPHQQ...QMFEEE..........-LP.A.SQDeEEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDTE.KKKL.EEGEK--..---.PQK........GETENLGTQIEQ...RPG.................SSSSSERSLSGSI..PR.GHKRKL......NEDDAAS.................ESSKESS.NEDEEGS.SSEADEMAAALEAELNDFM..............................
CTDP1_MOUSE/706-960               .......................................ERWDKVEEQLFPLIDDDTRTH.RD..NSPAVFPDRH..S.VLPTALFHPTPIHSKA..HPGPEVRIYDSNTGKLI.RMGPQGS-----...-APAPSSA....PLNHGEP.SSFRAVQPHQQ...QMFGEE..........-LP.E.SQD.GEQPGPAR...RKRQPS...MSEAM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDIE.KKKP.EDQDNEQ..ERA.PKP........RKPRAPGIRREQ...PVG.................LPSSGERSTPGMR.gPR.GHKRKL......NEEDAAS.................ESSGESS.NDDEEGS.SSEADEMAAALEAELNDLM..............................
G6DTG6_DANPL/536-680              ................................rppahcn---------------------.--..----------..-.----------------..-----------------.------------...--------....-------.-----------...------..........---.-.---.SPPPAPAV...RKRTPSgrfMDTIN.PL.LSFSSDDIADMDREVEDIFNE-SD.ESSSDdEEKVlGDNDEEN..ITE.DRL........LSLESGNSAQER..lQEK.................LNEDSNDSNTEDG..ER.ALKRPRp...stP------.................-------.-------.-------------------sddegppddddtswnlmgaalerefl....
H2U7R4_TAKRU/680-938              .......................................ERWERVEEQLYPLKEDYSKKS.RS..SSPAAFHENL..S.SLQKHVFQAAAIRHKP.vPPAPEIRTYDPVTGKLI.RRGPQVSRPPVF...QTPGP---....---LAEQ.SCLRGTSNCQP...A----E..........SAG.S.SQD.DEQPGPSR...RKRQLS...MSETM.PL.YTLCKEDLDSMDREVDDILGEESDnESEGRgKDKP.GNEEDVK..---.---........HKPGKT--KGSR...LTC.................PASMFKTNTAGFG..TM.GHKRKH......SDEEEEEdvekee....eaaaeslDESSKDS.NEEEGSS.SSEADEMAAALEAELNDFI..............................
V8P7X6_OPHHA/551-806              .......................................ERWDKVEEQLFPLKEDYFKTQ.RE..NSPAMFPDIP..S.AFQTALFHPTPIHPKC..QPGPEVRLYDPNTGKLI.RKGSQNSNQSLY..iQAPAPPLT....LPVHGEH.SLFRAVQPHQQ...-LFDEE..........EVP.A.SEN.-EEPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKT.EEEKQE-..---.PHS........TTKETLNIKVEE...RSV.................STSSSERSLTGSI..PR.GHKRKL......ADDDVAS.................ESSKGSS.NEDEEGS.SSEADEMAAALEAELNDFM..............................
H0UYY7_CAVPO/713-966              .......................................ERWDKVEEQLFPLIDDDSRPH.RE..NSPATFPDRQ..S.VIPATLFHPMPIHPKV..QPGPEVRIYDSYTGKLI.RMGAQGP-----...-VQGPP-S....LPIHREP.TSFRAVLPHQQ...QMFGEE..........-LP.D.ARD.GEQPGPAR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKP.EEQDDDQ..ERA.SQP........RKPKAPAAHREQ...PLG.................SSSSSERSAAGNR.gAR.GHKRKL......NDEDAAS.................ESSKESS.NEDEEGS.SSEADEMAAALEAELNDFM..............................
Q98SN2_XENLA/721-980              .......................................ERWEKVEEQLFPLKDDYMKSQ.RT..ISPTTFPDVQ..S.AFQTPLFHPSPIHPNT..QPGPEVHLYDPVTGKLI.RKGSQASRESPY..iQAPSPSV-....TPVHGEH.SSFRVVQPHQE...QLFDDE.........eLAT.A.NPD.EEQSGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKT.IKIKKSQ..I-A.AQG........NKLK----NPEE...RNE.................SSSSSERSLSGSR..PR.GHKRKLe...eeEEEDAES.................EISKESS.NEDEEGS.SSEADEMAAAIEAELNDFI..............................
G1LUZ4_AILME/646-841              .......................................ERWDRVEEQLFPLRDDYGRAQ.RE..DGPAAFPDRQ..G.ALPTALFHPTPVHPRA..QPGPEVRIYDANTGKLI.RKGAVG------...--PGPPGS....LAVHTEH.SSFRVVQPPRQ...-MLAQE..........-LP.D.SRP.GEQPGPSG...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKRP.EEERQER..---.PPP........REPQAPL-----...---.................-------------..--.------......-------.................-------.-------.-------------------eavacserttagsrgpr.............
G3P1I5_GASAC/706-847              .......................................ERWERVEEQLYPLREDCSKTP.RS..ISPAAFPDTQ..G.SPQTHVFQPAPVHSRP..-AAPEVRTYDPVTGKLI.RRGPQAPRPASY..lQGS-----....---SGEQ.PGLRGTSQRQQ...----DE..........AGG.S.SRD.DEQPGPSR...RKRQPS...MSESM.PL.YLLCKEDLDSMDREV---------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------..............................
W5L335_ASTMX/692-972              .......................................ERWERVEEQLFPLKEGYTKSF.RS..NSPSTFPDVQ..E.SFRAPVIRPSPIQSKL..PPAPEVRTYDPVTGKLI.RRGPPASSHPSY..lQSHRTSTT....MPGQDMH.SNFRLNLGSQQ...Q---EE..........VEG.S.NQD.DVKPGPSR...RKRQPS...MSESM.PL.YMLCKEDLESMDKEVDDILGEESDnESEEKgKEER.MEQEQEK..EKE.AEVqpp..ncgQSASATRVQQDP...A-Tlv.............kdTALTPPSSVSESA..PR.GQKRKLk....eSKDDDEDnddk........dgdsaSQSSKDS.NEEADDS.SSEADEMAAALELELNDFI..............................
Q569U3_XENLA/718-979              .......................................ERWEKVEEQLFPLKEDYTKSQ.RA..ISPTTFPDVQ..S.AFQTPLFHPTPIHPKT..QPGPEVHLYNPVTGKLI.RKGSQGSSQSPY..iQAPSPPLT....LPVHGEH.SSFRVVQPHQE...QLFDDE.........ePPT.A.NQD.EEQSGPSR...RKRQPS...MSESM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKT.VKVKKSQ..-SA.AQG........DKLKNPEERTE-...-TP.................SSSSSEKSLSGTR..PR.GHKRKLe....eEEEDAES.................VSSKESS.NEDEEGS.SSEADEMAAAIEAELNDFI..............................
H2QER0_PANTR/820-925              .....................................lp---------------------.--..----------..-.----------------..-----------------.------------...--------....-------.-----------...------..........---.-.---.--------...------...-----.--.-----------DAQVDDILGEGSD.DSDSE.KRRP.EEQEEE-..---.PQP........RKP---GTRRER...TLG.................APASSERSAVGGR.gPR.GHKRKL......NEEDAAS.................ESSRESS.NED-EGS.SSEADEMAKALEAELNDLM..............................
K7FCQ3_PELSI/605-759              ....................................ehd---DSVKTQSFNSIEEIITFN.RE..NSPATFPDTH..S.AFQTALFHPTPIHPKF..QPGPEVRLYDPNTGKLI.RKGSQSSGQPLY..iQSPAPPLT....LPVHGEH.SSFRVVQPHQQ...QLFDEE..........ELP.A.SEN.EDQPGPSK...RKRQPS...MSETM.PL.YTLCKEDLESMDKEV---------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------..............................
U3J536_ANAPL/606-870              .......................................ERWDKVEEQLFPLKDDYIKTH.RE..NSPATFPDTH..S.TFQTALFHPTPIHPKS..QPGPEVRLYDPNTGKLI.RKGSQTPGQPVY..iQSPAPPIT....LPVHGEH.SSFRVVQPHQQ...QIFEED..........DLP.A.SGN.EEQPGPSK...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.ESDSE.KKKP.EKEGEKP..QMC.PKQ........TSLSADNITEVT...PVSr..............veGKGTHKLPGSQKS..PW.GHKRKL......DEDDAAS.................ESSKESS.NEDEEGS.SSEADEMAAALEAELNDFM..............................
G7PWA5_MACFA/616-861              .......................................ERWDKVEEQLFPLRDDHSKSD.RE..NSPAAFPDRE..G.VPPTTLFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPPSS....LPLHREP.SSFRAVPPPQP...QTFGEE..........-LP.D.APD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KRRP.EEQEEE-..---.PQP........R---TPGARRER...TLG.................AAASSERSVAGGR.gPR.GHKRKL......NEEDAAS.................ESSRESS.NED-EGS.SSEADEMAKALEAELNDLM..............................
S9WY50_9CETA/506-555              .....................................sf---------------------.--..----------..-.----------------..-----------------.------------...--------....-------.-----------...------..........---.-.---.--------...------...-----.--.------------------------.-----.----.-------..---.---........------------...---.................-------------..-R.GHKRKL......SEEDAAS.................GSSCEDEeDEDEEGG.SSEADEMAAALEAELGDLM..............................
U3DU16_CALJA/716-961              .......................................ERWDKVEEQLFPLRDDHTKAQ.RE..NSPAAFPDRE..G.VPPTALFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPPSS....LPIRQEP.SSFRAVPPPQP...QMFDEE..........-LP.D.AQD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KRRP.EEQEEEL..---.-QP........RKPE---ARREQ...TLG.................ASASSERSMAGGR.gPR.GHKRKL......NEEDAAS.................ESSRGSS.NED-EGS.SSEADEMAAALEAELNDLM..............................
Q4S035_TETNG/691-979              .......................................ERWERVEEQLYPLKDDYSKKS.RS..NSPAAFHENL..G.SLQKRVFQSAAIRLKP.aAPAPEIRTYDPVTGKLI.RRAPQASAPPAF...HAPGP-LS....LSDQIEP.SCLRGTSNCRP...A----E..........TAG.S.SQD.DEQPGPSR...RKRQLS...MSETM.PL.YTLCKEDLESMDKEVDDILGEESDnESEGRgKDKP.GNEEDEE..QQQ.QQQ........QQQPPPPQQQPG...PVEvkcrtsgpqalgldertPEPSSENNILGRV..PR.GHKRKF......DESDEEEeegrae....kevedssDESFKDS.NEEEGGS.SSEADEMAAALEAELNDFM..............................
Q9PT70_XENLA/606-867              .......................................ERWEKVEEQLFPLKDDYMKSQ.RT..ISPTTFPDVH..S.AFQTPLFHPTPIHPKT..QPGPEVHLYNPVTGKLI.RKGSQGSSQSPY..iQAPSPPLT....LPVHGEH.SSFRVVQPHQE...QLFDDE.........ePPT.A.NQD.EEQSGPSR...RKRQPS...MSESM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKT.VKVKKSQ..-SA.AQG........DKLKNPEERTE-...-TP.................SSSSSEKSLSGTR..PR.GHKAKLe....eEEEDAES.................VSSKESS.NEDEEGS.SSEADEMAAAIEAELNDFI..............................
C3YBP7_BRAFL/294-496              vpvreeadsslqhdgnaeqetdsdrqemvqaqnqpvdtp---------------------.--..----------..-.--------PVPTQPVAhqNPVEEVATYDPVTGKRV.RRHPYMYQQYPYppqHVMYPPTHgmypTELEFNH.PEIRGDHRFVP...HPYPEKp........hKDA.S.SAD.GEEPTSSRg.pRKRRLS..tIAETN.PL.MAFSSEDIANMDKEVEEAFSEDSDsESEGE.GGRG.ERDGDRG..E--.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------dsrgssdtvvs...................
F7F659_ORNAN/686-945              .......................................ERWDKVEEQLFPLKEDYVKTQ.RE..NSPATFPDTQ..S.AFQTALFHPTPIHPKC..QPGPEVRIYDPNTGKLI.RKGSQNPGQSLY..iQPPAPPLT....LPVHGEH.SSFRVVQPHQQ...QLFGEE..........ELP.A.NQD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.ESDSA.KKKR.PELDGRR..S--.QQP........RAPPARRGFTDA...GTP.................ESLFLQSAGERGM..AR.GHKRKR......PEADVAS.................ESSKESS.NEDEEGS.SSEADEMAAALEAELNDFM..............................
Q641F9_XENLA/717-977              .......................................ERWEKVEEQLFPLKDDYMKSQ.RT..ISPTTFPDVH..S.AFQTPLFHPTPINPNT..QPGPEVHLYDPVTGKLI.RKGSQASRESPY..iQAPSPSVT....LPVHGEH.SSFRVVQLHQE...QLFDDE.........eLAT.A.NPD.EEQSGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKT.IKIKKSQ..NAA.-QG........NKLK----NPEE...RNE.................SSSSSERSLSGSR..PR.GHKRKLe...eeEEEDAES.................EISKESS.NEDEEGS.SSEADEMAAAIEAELNDFI..............................
G5AP10_HETGA/714-963              .......................................ERWDKVEEQLFPLTDDDTRAH.RE..NSPAAFPDRQ..N.VIPTALLHPTPIHPKA..QPGPEVRIYDSNTGKLI.RMGV--------...--PGPPSS....LSVHREP.TSFRAVLPHQQ...QMFGEE..........-LP.D.ARD.GEQPGPAR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKP.EEQDDEQ..ERA.PRP........RKPKAPGPHREQ...PLG.................SCSSSERSAAGIR.gTR.GHKRKL......NDEDAAS.................ESSKESS.NED-EGS.SSEADEMAAALEAELNDLM..............................
T1IZ83_STRMM/580-734              ...............kdnlnnrmheninedkgktkgnqf---------------------.--..----------..-.----------------..-----------------.------------...--------....-------.-----------...------..........---.-.---.--------...------...-STTInPL.LSFTSEDIAQMDQEVDDMINEGGEeNSDEE.ESSS.DQKSVTN..KRQ.NLY........SDSEDESLSADY...PTGw..............npRKKRNANSPCKNA..VS.KIARRS......DEDSLPS.................DRSDQSS.DDDYAESiGSVDEEMAAAVERE-----fl............................
G3WH29_SARHA/661-814              .......................................ERWDKVEEQLFPLKEDYIKTQ.RE..NSPATFPDIQ..S.AFPTALFHPTPIHPKC..QPGPEVRIYDSNTGKLI.RKGTQNTGQSLY..iQSPASPVT....LPVHGEH.SSFRVVQPHQQ...QMFGEE..........-LP.T.SQDeDEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKE----------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------..............................
L8Y685_TUPCH/797-876              .....................dpdrlltravwasgqrhs---------------------.--..----------..-.----------------..-----------------.------------...--------....-------.-----------...------..........---.-.---.--------...------...-----.--.------------------------.-----.----.-------..---.---........------------...---.................NRSNAPAGLTSSLllFR.GHKRKL......NEADAAS.................ESSPGFS.AEE-EGS.SSEADEMAAALEAELHGFM..............................
G7NKA9_MACMU/616-861              .......................................ERWDKVEEQLFPLRDDHSKSD.RE..NSPAAFPDRE..G.VPPTTLFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPPSS....LPLHREP.SSFRAVPPPQP...QTFGEE..........-LP.D.APD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KRRP.EEQEEE-..---.PQP........R---TPGARRER...TLG.................AAASSERSVAGGR.gPR.GHKRKL......NEEDAAS.................ESSRESS.NED-EGS.SSEADEMAKALEAELNDLM..............................
T1K4P5_TETUR/462-572              .......................................ERWEKVDEILFELKKDDNFEA.IQ..DKPKSSPTPTpdS.GFEAG-SSSGESSSPT..NAFEECPVYDSVTGKKI.SKSQKDNLESAE..sKI------....-------.-----------...------..........---.-.---.--------...------...-----.--.------------------------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------lskpssskvfldedelqsenmhqfssls..
G1PIU1_MYOLU/585-836              .......................................ERWDKVEEQLFPLSEDYGKVQ.RE..DSPAAFPDRQ..G.ALPAALFHPTPVHPKA..QPGPDVRIYDASTGKLI.RKGTTS------...--PGPPGS....LQIHTGH.SSFRAVQPHQQ...QMFGEE..........-LP.D.NPD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKP.EEQEEEQ..DGA.PQP........REPKAPAAQRGH...TLQ.................SKSPSERSAAEAR.gPR.GHKRKL......NDDDAAS.................ESSRESS.CEDEEGS.SSEADEMAAALEAELD---lm............................
F8W4I4_DANRE/676-947              .......................................ERWERVEEQLFPLKEDYNKSH.RS..NSPGAFLDIH..G.SAPRPPFQAPQVQPKP..LPAPEMRTYDPVTGKLI.RRGPQASRPPSY...LHSHPSSS....MSAKGDL.SNLRSAQGSQQ...---TDE..........PAG.S.SPD.DEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLDSMDKEVDDILGEESDnESEGKgKAGR.IEEEEEE..-VR.PHTs......kQKPPATDHIPPL...--Aavv..........eetsQTSTSEVCVTENV..LR.GHKRKLeearedEDKDEED.................GDSSKDS.NEDDEGS.SSEADEMAAALEAELNDFM..............................
K9IV94_DESRO/594-845              .......................................ERWDKVEEQLFPLSEDYGKAP.RE..DGPAAFPDRQ..G.ALPAALFHPTPVHPRA..QPGPDVRIYDASTGKLI.RKGAAG------...--PGPPGS....LQVHAEH.SSFRAVQPHQQ...QMFGEE..........-AP.G.APD.AARPGPCR...RQRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKP.EEEEQEQ..EGG.AVP........REPEAPAAQRRP...TLE.................SRPPSEKSGADGR.gPR.GHKRKL......SEEDVAS.................ESSRASS.CEDEEGS.SSEADEMAAALEAELD---lv............................
Q6DRN5_DANRE/676-947              .......................................ERWERVEEQLFPLKEDYNKSH.RS..NSPGAFLDIH..G.SAPRPPFQAPQVQPKP..LPAPEMRTYDPVTGKLI.RRGPQASRPPSY...LHSHPSSS....MSAKGDL.SNLRSAQGSQQ...---TDE..........PAG.S.SPD.DEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLDSMDKEVDDILGEESDnESEGKgKAGR.IEEEEEE..-VR.PHTs......kQKPPATDHIPPL...--Aavv..........eetsQTSTSEVCVTENV..LR.GHKRKLeearedEDKDEED.................GDSSKDS.NEDEEGS.SSEADEMAAALEAELNDFM..............................
H9J3M1_BOMMO/547-688              ..............................spppppapv---------------------.--..----------..-.----------------..-----------------.------------...--------....-------.-----------...------..........---.-.---.-----AAL...RRRTPSgrfMDTIN.PL.LSFSSDDIADMDREVEDIFNE-SD.ESSTD.DEKP.SQDDVDD..EEN.LKE........DQLIRIDEESTQdrlQET.................QDSSNESENDEEQ..PR.PRKRPR......KSTPPSD.................E----EP.PDD-DDS.S--WNLMGAALER------efl...........................
G3TL65_LOXAF/666-926              .......................................ERWDKVEEQLFPLRDDYTRMQsRE..TSPAAFADRQ..S.AFQTALFHPTPVHPRS..PPSPEARIYDASTGKLI.RKGAQRTVPPPY..aQAPAPPAS....LSAHGEH.SSFRVVQPHQQ...QMFDEE..........-LR.D.NPD.EEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKL.EEEEEE-..-GK.PPN........REAKAPGARAEQ...KAT.................LSWSSEQSLAGSV.vPR.GHKRKL......NEEDAAS.................DSSKESS.NEDEEGS.SSEADEMAAALEAELSDFM..............................
R0LIA4_ANAPL/630-788              .......................................ERWDKVEEQLFPLKDDYIKTH.RE..NSPATFPDTH..S.TFQTALFHPTPIHPKS..QPGPEVRLYDPNTGKLI.RKGSQTPGQPVY..iQSPAPPIT....LPVHGEH.SSFRVVQPHQQ...QIFEED..........DLP.A.SGN.EEQPGPSK...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVSLI------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------v.............................
U3KFV6_FICAL/613-872              .......................................ERWDKVEEQLFPLKDDYIKTH.RE..NSPATFPDTP..S.TFQTALFHPTPIHPKS..QPGPEVRIYDPNTGKLI.RKGTQTSGQSMY..iQSPAPPIT....LPVHGEH.SSFRVVQPHQQ...QMFEED..........DLP.A.TEN.EEQPGPSK...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.ESDTE.KKKP.EEEGEKP..---.-QT........SATEIPGRKADQ...RPGs...............sSSSSSERSLTGSL..PR.GHKRKL......DEDDAAS.................ESSKESS.NEDEEGS.SSEADEMAAALEAELNDFM..............................
H2ZXN9_LATCH/586-846              .......................................ERWERVEEKLFPLKEDYIKTQ.RA..NSPATFPDLP..G.AFQTPLFHPTPIHPKA..LSGPEVRIYDPNTGKLI.RKGSQSSRQSPY..iQPPGPPVK....LAVHGEQ.SSFRVVQPQQQ...QQMLDE..........EEM.T.GQD.EEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEDSDnDSDTE.KGKK.VEEEAKK..KQK.QKN........RHTENLGTKTVE...RLG.................-SSSSEGSLTGSV..PR.GHKRKL......-EDDSAS.................ESSKESS.NEDEEGS.SSEADEMAAALEAELNDFM..............................
F7G7V6_CALJA/716-965              .......................................ERWDKVEEQLFPLRDDHTKAQ.RE..NSPAAFPDRE..G.VPPTALFHPMPVLPKA..QPGPEVRIYDSNTGKLI.MTGARGP-----...--PAPPSS....LPIRQEP.SSFRAPPSLQP...QMFQNDc.......yeELP.D.AQD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KRRP.EEQEEEL..---.-QP........RKPE---ARREQ...TLG.................ASASSERSMAGGR.gPR.GHKRKL......NEEDAAS.................ESSRGSS.NED-EGS.SSEADEMAAALEAELNDLM..............................
K6ZJ11_PANTR/716-961              .......................................ERWDKVEEQLFPLRDDHTKAQ.RE..NSPAAFPDRE..G.VPPTALFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPSSS....LPIRQEP.SSFRAVPPPQP...QMFGEE..........-LP.D.AQD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KRRP.EEQEEE-..---.PQP........RKP---GTRRER...TLG.................APASSERSAVGGR.gPR.GHKRKL......NEEDAAS.................ESSRESS.NED-EGS.SSEADEMAKALEAELNDLM..............................
Q4STX2_TETNG/1-59                 .......................................---------------------.--..----------..-.----------------..-----------------.------------...--------....-------.-----------...------..........---.-.---.--------...------...-----.--.------------------------.-----.----.-------..---.---........------------...---.................-------------..--.GHKRKF......DESDEEEeegrae....kevedssDESFKDS.NEEEGGS.SSEADEMAAALEAELNDFM..............................
H0Z8E0_TAEGU/600-859              .......................................ERWDKVEEQLFPLKDDYIKTH.RE..NSPATFPDTP..S.TFQTALFHPTPIHPKS..QPGPEVRIYDPNTGKLI.RKGTQTSGQSMY..iQSPAPPIT....LPVHGEH.SSFRVVQPHQQ...QMFEED..........DLP.G.SEN.EEQPGPSK...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.ESDTE.KKKT.EEEGER-..---.PQT........CATETLGRKSDQ...RPGs...............sSSSSSERSLTGSV..PR.GYKRKL......DEDDAAS.................ETSKESS.NEDEEGS.SSEADEMAAALEAELNHFM..............................
K7CNU2_PANTR/716-961              .......................................ERWDKVEEQLFPLRDDHTKAQ.RE..NSPAAFPDRE..G.VPPTALFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPSSS....LPIRQEP.SSFRAVPPPQP...QMFGEE..........-LP.D.AQD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KRRP.EEQEEE-..---.PQP........RKP---GTRRER...TLG.................APASSERSAVGGR.gPR.GHKRKL......NEEDAAS.................ESSRESS.NED-EGS.SSEADEMAKALEAELNDLM..............................
H2MEM1_ORYLA/697-843              .......................................ERWERVDEQLYPLKDDYSKTP.RS..NSPAAFAESQ..G.STQKPAFQPTPIQPRP.pPPAPESRTYDPVTGKLI.RRGPNVQRPPSY...LHPSS---....-SEPRDQ.PSLRAAAPTPL...---KEA..........-AG.C.VQD.GEQAGPSR...RRRQPS...MSETM.PL.YTLCKEDLESMDREV---------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------..............................
F7E4V3_MACMU/721-966              .......................................ERWDKVEEQLFPLRDDHSKRQ.LE..NSPAAFPDRE..G.VPPTTLFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPPSS....LPLHREP.SSFRAVPPPQP...QTFGEE..........-LP.D.APD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KRRP.EEQEEE-..---.PQP........R---TPGARRER...TLG.................AAASSERSVAGGR.gPR.GHKRKL......NEEDAAS.................ESSRESS.NED-EGS.SSEADEMAKALEAELNDLM..............................
H2QER0_PANTR/716-824              .......................................ERWDKVEEQLFPLRDDHTKAQ.RE..NSPAAFPDRE..G.VPPTALFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPSSS....LPIRQEP.SSFRAVPPPQP...QMFGEK..........-LP.D.A--.--------...------...-----.--.------------------------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------q.............................
M1EJH0_MUSPF/575-819              .......................................ERWDRVEEQLFPLREDYGRVQ.RE..DGPAAFPDRQ..G.APPAALFHPTPVHPRA..QAGPDVRIYDANTGKLI.RKGAAG------...--PGPPGS....LAVHAEH.SSFRVVQPPRQ...-TLAQE..........-LP.D.SRP.GEQPGPSG...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDTE.KKRP.EEEQQEQ..---.PPP........REPQATL-----...--E.................ATPCGERTSAGSR.gPR.GHKRKL......PEEDVGGvs.............sgASSGESS.GADEEGS.SSEADEMAAALEAELSDL-..............................
I3MHY0_SPETR/624-878              .......................................ERWDRVEEQLFPLTEDDARTH.RE..NSPTAFPDRH..S.MLPAALFHPTPVHPKA..QPGPEVRIYDSNTGKLI.RTGAQGP-----...-TPAPAGS....LPVHGES.SSFRAVQPQQP...QMFGEE..........-LP.D.VRD.GERPSPAR...RKRQPS...MSETM.PL.YTLCREDLESMDKEVDDILGEGSD.DSDSE.KRRP.EEQGEER..EGA.ARP........REPKAPSAQRGP...PLG.................PASSSDRSTAGTR.gPR.GHKRKL......NEEDAAS.................ESSKESS.NEDEEGS.SSEADEMAAALEAELNELM..............................
K7EJD2_HUMAN/648-794              .......................................ERWDKVEEQLFPLRDDHTKAQ.RE..NSPAAFPDRE..G.VPPTALFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPSSS....LPIRQEP.SSFRAVPPPQP...QMFGEE..........-LP.D.AQD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKE----------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------rp............................
U3B9J0_CALJA/716-839              .......................................ERWDKVEEQLFPLRDDHTKAQ.RE..NSPAAFPDRE..G.VPPTALFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPPSS....LPIRQEP.SSFRWTTSLEK...AAMTAT..........---.-.---.--------...------...-----.--.------------------------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------arrggqrsrrrssspgsprp..........
W4Z059_STRPU/503-672              ................sqkakkgkgkakastngnpgstg---------------------.--..----------..-.----------------..-----------------.------------...--------....-------.-----------...------..........---.-.---.--MPGQRT...KSRPLS...MSEDYnPM.YSFSSEDLASMGKEVEDMFGSSSG.ESSSS.SSSS.ESEND--..---.-AR........SNPTSLGSVT--...RPA.................SSSSSEESLTAEN..PR.GWKRKR......DEMEDKDddvndfdp.fqrpvedsSSSAGLS.EGEEWFS.EEEGQKMANAID-------dllt..........................
G1SKL9_RABIT/585-838              .......................................ERWDKVEEQLFPLRDDDAKTP.RE..NSPAASLDKQ..G.VLPTALFHPAPVHAKA..QPGPEVRIYDSKTGKLI.RTGAQGP-----...-GPAPCSS....LPPHGEPsSSFRAAQP--Q...QMFGGA..........-AP.D.ACD.REQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDREVDDILGEGSD.DSDSE.KKKA.DGQEEEQ..EGR.PPP........SKPEAWGARGEQ...PLG.................PSACSERTGASVR.gPR.GHKRKL......SEDGTAS.................DSSRESS.DADGEGS.SSEADEMAAALEAELSDLV..............................
F7HRQ5_MACMU/721-843              .......................................ERWDKVEEQLFPLRDDHSKRQ.LE..NSPAAFPDRE..G.VPPTTLFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPPSS....LPLHREP.SSFRWTTSSEK...AVTTAT..........---.-.---.--------...------...-----.--.------------------------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------arrgglrsrrrspspgrqg...........
G3HCQ6_CRIGR/594-848              .......................................ERWDKVEEQLFPLIDDDARAH.RG..NSPAAFPDRQ..N.VLPAALFHPTPIHSKA..HPGPEVRIYDSNTGKLI.RMGTQGP-----...-APAPSSA....PLIHGEP.SSFRAVQPQQQ...QMFGEE..........-LP.E.AQD.GEQPGPAR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKP.EYQENEQ..ERA.PKS........RKPRTPGIRREQ...PLG.................LSSSGERSATGMR.gPR.GHKRKL......NEEDAAS.................ESSGESS.NDDEEGS.SSEADEMAAALEAELNDLM..............................
H2U7R2_TAKRU/691-964              .......................................ERWERVEEQLYPLKEDYSKKS.RS..SSPAAFHENL..S.SLQKHVFQAAAIRHKP.vPPAPEIRTYDPVTGKLI.RRGPQVSRPPVF...QTPGP---....---LAEQ.SCLRGTSNCQP...A----E..........SAG.S.SQD.DEQPGPSR...RKRQLS...MSETM.PL.YTLCKEDLDSMDREVDDILGEESDnESEGRgKDKP.GNEEDDE..QQP.QQQ........--PESAEMSSDH...TESrecg........gtdvnLTSVYDTCVVINV..CE.GHKRKH......SDEEEEEdvekee....eaaaeslDESSKDS.NEEEGSS.SSEADEMAAALEAELNDFI..............................
G1MTK5_MELGA/626-779              .......................................ERWDKVEEQLFPLKDDYIKTH.RE..NSPATFPDTH..S.TFQTALFHPTPIHPKS..QPGPEVRLYDPNTGKLI.RKGSQTSGQSMY..iQSPAPPIT....LPVHGEH.SSFRVVQPHQQ...QIFEED..........-LP.V.TEN.EEQPGPSK...RKRQPS...MSETM.PL.YTLCKEDLESMDKEV---------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------..............................
S4NHB6_9NEOP/1-125                ...................................mdsl---------------------.--..----------..-.----------------..-----------------.------------...--------....-------.-----------...------..........---.-.---.--------...------...----N.PL.LSFSSDDIADMDREVEDIFNE-SD.ESSSDdEEKP.TDDVDDE..ENI.SEDrl...lslE---TSQSSQD-...RLGen.............keGNDSS-DSNTEDG..ER.PRKRPR......P----ST.................PPSDDDV.PPDDDDS.SW--NLMGAALERE-----fla...........................
G3R674_GORGO/683-928              .......................................ERWDKVEEQLFPLRDDHTKAQ.RE..NSPAVFPDRE..G.VPPTALFHPMPILPKA..QPGPEVRIYDSNTGKLI.RMGARGP-----...--PAPSSS....LPIRQEP.SSFRAVPPPQP...QMFGEE..........-LP.D.AQD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KRRP.EEQEEE-..---.PQP........RKP---GTRRER...TLG.................APASSERSAAGGR.gPR.GHKRKL......NEEDAAS.................ESSRESS.NED-EGS.SSEADEMAKALEAELNDLM..............................
F6PKT6_CIOIN/662-822              .......................................DRWERVSEKLFPMPSKSSRHS.RS..RSGT--PPVH..K.YMFTTINNP-AVNVTP..AQTSEKR-YDAVTGKLL.KKVLDP----RF...EFMVSEAV....TRKQKRK.SPLYTSLKNPE...KVIPVQ.........fNQS.S.NEAsTSTAVSAT...RTRKPS...MAEVM.GIgYTLSSNDIEDMDKEVEDLMNSDED.DG---.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------d.............................
L5KKR6_PTEAL/673-918              .......................................ERWDRVEEQLFPLSDDYGKAP.RE..DGPAAFPERQ..G.ALAPTLFHPTPIHPRA..QPGPEVRIYDASTGKLI.RKGAAG------...--PGPPGP....PQVHAER.PSFRAVEPHQQ...QLFGEE..........-LP.D.NAD.GEQPGP-R...RKRQPS...MSEAM.PL.YTLCKEDLESMDKEVDDILGEGSD.ESDSE.KRRP.EEPEDEQ..EAG.PQP........REPMALGAPRG-...---.................PKSASQRGTGDGR.gPR.GHKRKL......REEDAAS.................ESSRESS.CED-EGS.SSEADEMAAALEAELD---lm............................
M3YYY9_MUSPF/617-759              .......................................ERWDRVEEQLFPLREDYGRVQ.RE..DGPAAFPDRQ..G.APPAALFHPTPVHPRA..QAGPDVRIYDANTGKLI.RKGAAG------...--PGPPGS....LAVHAEH.SSFRVVQPPRQ...-TLAQE..........-LP.D.SRP.GEQPGPSG...RKRQPS...MSETM.PL.YTLCKEDLESMDKE----------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------..............................
E0CZ13_MOUSE/4-172                ...................................itlv---------------------.--..----------..-.----------------..-----------------.------------...--------....-------.--VRAVQPHQQ...QMFGEE..........-LP.E.SQD.GEQPGPAR...RKRQPS...MSEAM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDIE.KKKP.EDQDNEQ..ERA.PKP........RKPRAPGIRREQ...PVG.................LPSSGERSTPGMR.gPR.GHKRKL......NEEDAAS.................ESSGESS.NDDEEGS.SSEADEMAAALEAELNDLM..............................
M3VV05_FELCA/623-865              .......................................ERWDRVEEQLFPLRADYGRAQ.RE..DGPAAFPDRQ..G.ALPTALFHPTPVHPRA..QSGPEVRIYDANTGKLI.RKGAVG------...--PGPPSS....LAVHTEH.SSFRVVQPPP-...QMLAQE..........-LP.D.TRR.GERPGPGG...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KRRP.EEEGPQ-..-ER.PLP........REPRATL-----...--E.................ATASSERSTADSR.gPR.GHKRKL......PEEDTGS.................ASSGESS.GEDEEGS.SSEADEMAAALEAELNDLM..............................
E2R1Y2_CANFA/692-933              .......................................ERWDRVEEQLFPLRDDYGRAQ.RE..DGPAAFPDRQ..G.ALPTALFHPTPVHPRT..QPGPEVRIYDANTGKLI.RKGAVG------...--PGPPGS....LAVHTEH.SSFRVVQPPRQ...-MLAQE..........-LP.D.SRP.GEQPGPSG...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDNE.KRRP.EEERKER..---.PPP........REPQATP-----...--E.................ATPSSERTRAGSR.gPR.GHKRKL......PEEDAGS.................ASSGESS.GEDEEGS.SSEADEMAAALEAELNDLM..............................
U3CFF3_CALJA/716-838              .......................................ERWDKVEEQLFPLRDDHTKAQ.RE..NSPAAFPDRE..G.VPPTALFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPPSS....LPIRQEP.SSFRWTTSLEK...AAMTAT..........---.-.---.--------...------...-----.--.------------------------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------arrggqrsrrrssspgslr...........
M3ZU95_XIPMA/716-1000             .......................................ERWERVEEQLYPLKEDYSRTP.RS..NSPATFLDNQ..G.CLQKAVFQPAPVHPRP.rGAFSEARTYDSVTGKLI.RRGPQAGRPSAY..lQVSGP---....LSDRMDQ.SGLRGAAQGQQ...----DE..........AAG.S.SQD.DEQPGPSR...RERQPS...MSETM.PL.YTLCKEDLDSMDKEVDDILGEESDnESEGRgKEKP.GNEDIAEeeEEE.QQQ........QQPEAGELTTSG...PPSkpdgv.......eerlqTTPPCDSSLSENV..PR.GQKRKYdd..agE--DEEDadvesk....qegrdsaDESFKDS.NEEEEGS.SSEADEMAAALEAELNDFM..............................
H0XQT5_OTOGA/698-867              .......................................ERWDKVEEQLFPLKEDDARAQ.RY..GGPAAFSDRE..G.VPQTTLFHPMPVHPKA..PPGPEVRVYDSSTGKLV.RTGAQGP-----...-RPTPPGA....LPVHQEP.SSFRAVPPQ-Q...QMFGEE..........-LP.D.ARD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKQP.GEQEEE-..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------..............................
V9KFN1_CALMI/514-793              .......................................ERWERVDEQLFPLKEDYVKTQ.RC..NSPASFPEIQ..C.GFQTPLLHPTPIHPKT..QPGPEVRIYDPNTGKLI.RKDSQGNRQSTY..iQPPAPPVT....LPVHGEQ.SSFRVVQPHQH...QMLDED..........ELPnS.SQS.EEKPGPSRagsRKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEDSDnESESE.KEER.MEEKEQP..RPK.QEE........RQQQEQQQQHQQ...TPEtgasekp..eteiearpNSSSSEGSLTGSV..PR.GHKRKL......EEDEVGS.................DSSKLSS.NED--DS.SSEADEMAAALEAELNDFI..............................
B7PHL5_IXOSC/100-183              .......................................ERWEHVHEALFPLEAEVPAEA.RRaqRLPSTAATAR..A.AEPRREEAAAADPTRE..AAAP---VYDAVTGKRIwRNGPQQQRD---...--------....-------.-----------...------..........---.-.---.--------...------...-----.--.------------------------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------vaeagcvt......................
B2L510_XENBO/6-35                 .......................................ERWEKVEEQLFPLKDDYMKSQ.RT..ISPTTFP---..-.----------------..-----------------.------------...--------....-------.-----------...------..........---.-.---.--------...------...-----.--.------------------------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------..............................
F1NZN8_CHICK/678-940              .......................................ERWDKVEEQLFPLKDDYIKTH.RE..NSPATFPDTH..S.TFQTALFHPTPIHPKS..QPGPEVRLYDPNTGKLI.RKSSQTSGQSMY..iQSPTPPIT....LPVHGEH.SSFRVVQPHQQ...QIFEED..........-LP.V.TEN.EEQPGPSK...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.ESDSE.KKKP.EEKGEK-..---.PQI........SATEATGVKTDQ...RPRsss...........sslSSSSSEKSLTGSV..PR.GHKRKL......DEDDAAS.................ESSKESS.NEDEEGS.SSEADEMAAALEAELNDFM..............................
F7B1B3_XENTR/717-978              .......................................ERWEKVEEQLFPLKDDYMKSQsRA..ISPTTFPDIQ..S.AFQTPLFHPTPIHPKT..QPGPEVRLYDPVTGKLI.RKGSQGSSQSPY..iQAPSPPLS....LPVHGEH.SSFRVVQPHQE...QLFDDD.........eELP.TaNSD.EEQSGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKT.IKVKKSQ..-SA.EQG........NKLK----NPEE...RTE.................SSSSSERSLSGSR..PR.GHKRKLe....eEEEDAES.................ESSKESS.NEDEEGS.SSEADEMAAAIEAELNDFI..............................
S9WY50_9CETA/419-509              .......................................ERWDKVEEQLFPLRDDHGRAQ.RE..DGPAAFPDRQ..G.VLPTTLFHPTPVHPRA..PPGPEARVYDASTGRLI.RKGAAG------...--PGPPGS....LPVHAEL.SSFR-------...------..........---.-.---.--------...------...-----.--.------------------------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------g.............................
H2U7R3_TAKRU/691-956              .......................................ERWERVEEQLYPLKEDYSKKS.RS..SSPAAFHENL..S.SLQKHVFQAAAIRHKP.vPPAPEIRTYDPVTGKLI.RRGPQVSRPPVF...QTPGP---....---LAEQ.SCLRGTSNCQP...A----E..........SAG.S.SQD.DEQPGPSR...RKRQLS...MSETM.PL.YTLCKEDLDSMDREVDDILGEESDnESEGRgKDKP.GNEEDDE..--Q.QPQ........QQPESAELCRDR...PVG.................LLAPTTRSRANVE.gRM.GHKRKH......SDEEEEEdvekee....eaaaeslDESSKDS.NEEEGSS.SSEADEMAAALEAELNDFI..............................
L5M062_MYODS/573-823              .......................................ERWDKVEEQLFPLSEDYGKVQ.RE..DSPAAFPDRQ..G.ALPAALFHPTPVHPKA..QPGPDVRIYDASTGKLI.RKGTAS------...--PGPPGS....LQIHTGH.SSFRAVQPHQQ...QMFGEE..........-LP.D.NPD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKP.EEQEEEQ..DGA.SQP........REPKAPAAQRGH...TLQ.................SKSPSERSAAEAR.gPR.GHKRKL......NDDDAAS.................ESSRESS.CED-EGS.SSEADEMAAALEAELD---lm............................
G1KVK5_ANOCA/709-958              .......................................ERWDKVEEQLFPLKDDYLKTQ.RE..NSPAMFPDIH..S.AFQTALFHPTPIHPKC..QPSPEVRLYDPNTGKLI.RKGSQNS-----...-TPSPPLN....LPVHGEH.SLFRIVQPHQQ...-LFDED..........GMP.S.SEN.-EEPGPSK...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKG.RGRKEK-..--A.PQN........NKKDPINIKTEE...RPV.................STSSSERSFTGSI..PR.GHKRKL......VEDDVAS.................ESSKGSS.NEDEEGS.SSEADEMAAALEAELNDFM..............................
G1RAC4_NOMLE/717-843              .......................................ERWDKVEEQLFPLRDDHTKAQ.RE..NSPTAFPDRE..G.VPLTALFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPPSS....LPIRQEP.SSFRWTTSSEK...AVTTAT..........---.-.---.--------...------...-----.--.------------------------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------arrgglrsrrrspspgsqgpags.......
H3D945_TETNG/652-908              .......................................ERWERVEEQLYPLKDDYSKKS.RS..NSPAAFHENL..G.SLQKRVFQSAAIRLKP.aAPAPEIRTYDPVTGKLI.RRAPQASAPPAF...HAPGP-LS....LSDQIEP.SCLRIIQKILKgtsNCRPAE..........TAG.S.SQD.DEQPGPSR...RKRQLS...MSETM.PL.YTLCKEDLESMDKEVDDILGEESDnESEGR.G--P.VEVK---..---.CRT........SGPQALGLDERT...---.................PEPSSENNILGRV..PR.GHKRKF......DESDEEEe..............egRAEKEDS.NEEEGGS.SSEADEMAAALEAELNDFM..............................
W5MPI5_LEPOC/712-875              .......................................ERWESVEEQLYPLKEDYIRTP.RS..SSPAGFPDAQ..G.ACPTPVFHPTPIHPRT..PAGPEVRTYDSVTGKLI.RKGPQSSRPSPY..aQASGPPVP....LPAHGDQ.SSFRVVQPPLP...QQEEEEeeeeeeeeeaSLG.P.SGD.KERPGPSR...RKRQPS...MSESM.PL.YTLCKEDLESMDKE----------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------..............................
D6WSR3_TRICA/594-758              ................................ehiisyp---------------------.--..----------..-.----------------..-----------------.------------...--------....-------.-----------...------..........---.-.---.-EHNTPAM...RKRTPSgrfMDTIN.PL.MSFSSADIADMDKEVEDILDDESD.SSDEE.KNAK.ATVVNSE..EVH.ENSsssddslgDHPKGFKRKREG...GDEae.............idLNNSTEDDETPSVkfRR.GETVDS......EVDMEPD................sQDSDGSV.EAPDEVD.DGEWNMMGAALERE-----fls...........................
L7LWR1_9ACAR/100-214              .......................................ERWEHVAEALFPLRPPSR-EG.AS..DRR-LQQDTI..SqHPKEPVAEVALLHEKQ.vEQVVESPVYDAVTGKRI.WRGRERTAGSGP...QAAAAG--....-------.-----------...------..........---.-.---.--------...------...-----.--.------------------------.-----.----.-------..---.---........------------...---.................-------------..--.------......-------.................-------.-------.-------------------saptptvseewpctasssksdhpqldekan
CTDP1_HUMAN/716-961               .......................................ERWDKVEEQLFPLRDDHTKAQ.RE..NSPAAFPDRE..G.VPPTALFHPMPVLPKA..QPGPEVRIYDSNTGKLI.RTGARGP-----...--PAPSSS....LPIRQEP.SSFRAVPPPQP...QMFGEE..........-LP.D.AQD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KRRP.EEQEEE-..---.PQP........RKP---GTRRER...TLG.................APASSERSAAGGR.gPR.GHKRKL......NEEDAAS.................ESSRESS.NED-EGS.SSEADEMAKALEAELNDLM..............................
#=GR CTDP1_HUMAN/716-961    SS    .......................................XXXXXXXXXXXXXXXXXXXXX.XX..XXXXXXXXXX..X.XXXXXXXXXXXXXXXX..XXXXXXXXXXXXXXXXX.XXXXXXX-----...--XXXXXX....XXXXXXX.XXXXXXXXXXX...XXXXXX..........-XX.X.XXX.XXXXXXXX...XXXXXX...XXXXX.XX.XXXXXXXXXXXXXXXXXXXXXXXX.XXXXX.XXXX.XXXXXX-..---.XXX........XXX---XXXXXX...XXX.................XXXXXXXXXXXXX.XXX.XXXXXX......XXXXXXX.................XXXXXXX.XXX-XXX.XSHHHHHHHHHHHHCTTT-..............................
W5P213_SHEEP/631-874              .......................................ERWGRVEGQVFPCHREPLSLV.RE..DGPASFPDRQ..S.LLPAALFHPTPVHPKA..PPGPEVRIYDASTGKLI.RTATSG------...--PGPPGA....LPHAGL-.SSFRAVQPRPQ...QVFGDD..........-LP.D.SQD.GEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDIVGARAQ.SSG--.RKRP.REGGQPP..EEG.PGH........GPPEALGAPRGR...---.................---RLERSAADGR.gLR.GHKRKL......NEEDAAS.................ESSGASS.CEDEEGG.SSEADEMAAALEAELGDLM..............................
M7BHU1_CHEMY/629-887              ......................................k-RWDKVEEQLLSLKDDYIKTQ.RE..NSPATFPDTH..S.VFQTALFHPTPIHPKF..QPGPEVRLYDPNTGKLI.RKSSQSSVQSPY..iQSPAPPLT....LPVHAEH.SSFRVVQPHQQ...QLFDEE..........ELP.A.NEN.EDQPGPSK...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDSE.KKKT.EEEGEKA..---.-QS........SATESLGMKIEE..rPGS.................SSSSSERSLTGSI..PR.GHKRKL......DEDDAAS.................ESSKESS.NEDEEGS.SSEADEMAAALEAELNDFM..............................
L8Y685_TUPCH/539-743              .......................................ERWDKVEEQLFPLRDDSSKVH.RW..VLGLLAKWAS..I.CCRGSDMSAHLGSAWS..TSRKLVRVYDSSTGKLI.RPAAQGP-----...-GPTPPST....LPDHREA.SSFRAVQPHQQ...QTFGEE..........-PA.D.TPS.GEQPGPTR...RRRQPS...LSETM.PL.YTLCKEDLESMDKEVDDILGEGSD.DSDTE.KKPP.EEQERE-..-GG.PPP........GEPEARGAPGER...AQA.................SSSSGERM-----..--.------......-------.................-------.-------.-------------------swnpeh........................
I3JLE3_ORENI/712-999              .......................................ERWERVEEQLYPLKEDYSKTA.RS..NSPALLPDNQ..G.SLQKPIFHPAPIHPRP.pPAAPEVRTYDSVTGKLI.RRGPQVSRPSAY..lHTSGS-ML....LSDPREQ.SGLRGTSQSQQ...----DE..........GVE.S.GRD.DEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLDSMDKEVDDILGEESDnESEGRgKEKP.GNEEMED..EEE.QQR........QRQQAGAGQTAE..rRLGpqals.......ieeklQTPSNVASQCQSV..AR.GQKRKHe...qdKEE---DdvdsnntedkeegekfvDESSKDS.NEEEEGS.NSEEDEMAAALEAELNDFM..............................
#=GC SS_cons                      .......................................XXXXXXXXXXXXXXXXXXXXX.XX..XXXXXXXXXX..X.XXXXXXXXXXXXXXXX..XXXXXXXXXXXXXXXXX.XXXXXXX-----...--XXXXXX....XXXXXXX.XXXXXXXXXXX...XXXXXX..........-XX.X.XXX.XXXXXXXX...XXXXXX...XXXXX.XX.XXXXXXXXXXXXXXXXXXXXXXXX.XXXXX.XXXX.XXXXXX-..---.XXX........XXX---XXXXXX...XXX.................XXXXXXXXXXXXX.XXX.XXXXXX......XXXXXXX.................XXXXXXX.XXX-XXX.XSHHHHHHHHHHHHCTTT-..............................
#=GC seq_cons                     .......................................ERW-+VEEQLFPL+-DasKsp.Rp..sSPAsFPDpp..u.sh.ssLFHPsPlpPKs..pPGPEVRlYDssTGKLI.RpGspus..........PuPs.o....Lsl+tE..SSFRsVpP.Qp...phhs-E...........hs.s.stc.tEQPGPSR...RKRQPS...MSETM.PL.YTLCKEDLESMDKEVDDILGEtSD.-S-sc.Kc+s.tcpppp........t.........pt....t..........t..................ssss-pshstth..sR.GHKRKh......p-c-.ts.................ppSttsS.s--.-GS.SSEADEMAAALEAELs-hh..............................
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