GenomeNet

Database: Pfam
Entry: FIVAR
LinkDB: FIVAR
Original site: FIVAR 
#=GF ID   FIVAR
#=GF AC   PF07554.12
#=GF DE   FIVAR domain
#=GF AU   Yeats C
#=GF SE   Yeats C
#=GF GA   29.20 11.10;
#=GF TC   29.20 11.10;
#=GF NC   29.10 11.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12438356
#=GF RT   Identification of a fibronectin-binding protein from
#=GF RT   Staphylococcus epidermidis. 
#=GF RA   Williams RJ, Henderson B, Sharp LJ, Nair SP; 
#=GF RL   Infect Immun 2002;70:6805-6810.
#=GF RN   [2]
#=GF RM   14759609
#=GF RT   Posttranslational processing of polysaccharide lyase: maturation
#=GF RT   route for gellan lyase in Bacillus sp. GL1. 
#=GF RA   Miyake O, Kobayashi E, Nankai H, Hashimoto W, Mikami B, Murata
#=GF RA   K; 
#=GF RL   Arch Biochem Biophys 2004;422:211-220.
#=GF RN   [3]
#=GF RM   10896508
#=GF RT   Tn551-mediated insertional inactivation of the fmtB gene
#=GF RT   encoding a cell wall-associated protein abolishes methicillin
#=GF RT   resistance in Staphylococcus aureus. 
#=GF RA   Komatsuzawa H, Ohta K, Sugai M, Fujiwara T, Glanzmann P,
#=GF RA   Berger-BachiB, Suginaka H; 
#=GF RL   J Antimicrob Chemother 2000;45:421-431.
#=GF DR   INTERPRO; IPR011490;
#=GF CC   This domain is found in a wide variety of contexts, but mostly
#=GF CC   occurring in cell wall associated proteins. A lack of conserved
#=GF CC   catalytic residues suggests that it is a binding domain. From
#=GF CC   context, possible substrates are hyaluronate or fibronectin
#=GF CC   (personal obs: C Yeats). This is further evidenced by [1].
#=GF CC   Possibly the exact substrate is N-acetyl glucosamine. Finding it
#=GF CC   in the same protein as Pfam:PF05089 further supports this
#=GF CC   proposal. It is found in the  C-terminal part of Swiss:O82833,
#=GF CC   which is removed during maturation  ([2]). Some of the proteins
#=GF CC   it is found in (e.g. Swiss:Q9RL69) are  involved in methicillin
#=GF CC   resistance ([3]). The name FIVAR derives from Found In Various
#=GF CC   Architectures. 
#=GF SQ   2021
#=GS A0A0A7G0Y7_9CLOT/1176-1238  AC A0A0A7G0Y7.1
#=GS B1C337_9FIRM/647-713        AC B1C337.1
#=GS C5NV36_9BACL/636-703        AC C5NV36.1
#=GS H1BJ97_9FIRM/1-37           AC H1BJ97.1
#=GS EBH_STAEQ/8459-8530         AC Q5HPA2.2
#=GS C0EGP9_9FIRM/143-208        AC C0EGP9.1
#=GS R6DWN1_9FIRM/1023-1090      AC R6DWN1.1
#=GS A0A0J1G477_9FIRM/1045-1112  AC A0A0J1G477.1
#=GS B1C0I8_9FIRM/955-1018       AC B1C0I8.1
#=GS R5KVP1_9CLOT/1391-1454      AC R5KVP1.1
#=GS N1ZJP3_9LACO/614-681        AC N1ZJP3.1
#=GS Q7NBE3_MYCGA/128-201        AC Q7NBE3.2
#=GS R5QS73_9FIRM/1641-1705      AC R5QS73.1
#=GS Q7NBQ9_MYCGA/81-145         AC Q7NBQ9.1
#=GS Q7NBR1_MYCGA/100-164        AC Q7NBR1.1
#=GS C0EDX4_9FIRM/1762-1825      AC C0EDX4.1
#=GS R6BWT6_9FIRM/32-104         AC R6BWT6.1
#=GS W1Q196_ABIDE/2382-2450      AC W1Q196.1
#=GS R5Q9W5_9FIRM/1552-1615      AC R5Q9W5.1
#=GS C0ECM8_9FIRM/1044-1108      AC C0ECM8.1
#=GS A0A0R2GSB1_9LACO/87-151     AC A0A0R2GSB1.1
#=GS L1QDW6_9CLOT/1957-2019      AC L1QDW6.1
#=GS R9LUY4_9FIRM/1633-1696      AC R9LUY4.1
#=GS Q8DX06_STRA5/1326-1393      AC Q8DX06.1
#=GS S0FEY5_9FIRM/907-970        AC S0FEY5.1
#=GS L1Q934_9CLOT/1630-1692      AC L1Q934.1
#=GS C0EID1_9FIRM/1109-1169      AC C0EID1.1
#=GS V9HES6_9CLOT/1417-1479      AC V9HES6.1
#=GS C0EJ21_9FIRM/1689-1730      AC C0EJ21.1
#=GS R5QCC3_9FIRM/977-1053       AC R5QCC3.1
#=GS G4D2F2_9FIRM/733-795        AC G4D2F2.1
#=GS R5QS73_9FIRM/1572-1637      AC R5QS73.1
#=GS I6TE07_ENTHA/1156-1219      AC I6TE07.1
#=GS R6QLS7_9CLOT/1902-1965      AC R6QLS7.1
#=GS L1Q4I7_9CLOT/1582-1644      AC L1Q4I7.1
#=GS C0ECN8_9FIRM/1136-1199      AC C0ECN8.1
#=GS Q833V2_ENTFA/1427-1493      AC Q833V2.1
#=GS C0EAI8_9FIRM/1498-1556      AC C0EAI8.1
#=GS K0YP02_9ACTO/422-478        AC K0YP02.1
#=GS E1L0K4_9ACTN/1533-1598      AC E1L0K4.1
#=GS R6BTC3_9FIRM/165-228        AC R6BTC3.1
#=GS B2TLL1_CLOBB/592-655        AC B2TLL1.1
#=GS B1BZG3_9FIRM/1260-1326      AC B1BZG3.1
#=GS F7KM67_9FIRM/479-543        AC F7KM67.1
#=GS L1QPC0_9CLOT/1640-1703      AC L1QPC0.1
#=GS B1C383_9FIRM/29-95          AC B1C383.1
#=GS B9Y2K8_9FIRM/685-747        AC B9Y2K8.1
#=GS A0A0D5ZJ14_9MOLU/1564-1627  AC A0A0D5ZJ14.1
#=GS C0EAS9_9FIRM/965-1030       AC C0EAS9.1
#=GS C5NWM6_9BACL/489-552        AC C5NWM6.1
#=GS Q7NBD2_MYCGA/74-138         AC Q7NBD2.1
#=GS Q7NBR4_MYCGA/164-237        AC Q7NBR4.1
#=GS G4D2F2_9FIRM/456-521        AC G4D2F2.1
#=GS A0A0R1S3M2_9LACO/464-530    AC A0A0R1S3M2.1
#=GS B1C337_9FIRM/785-848        AC B1C337.1
#=GS F5YR32_TREPZ/628-674        AC F5YR32.1
#=GS C0EGE7_9FIRM/1482-1548      AC C0EGE7.1
#=GS B1C1G5_9FIRM/1468-1534      AC B1C1G5.1
#=GS M8E383_9BACL/277-342        AC M8E383.1
#=GS G4D2F2_9FIRM/594-658        AC G4D2F2.1
#=GS C0EGH7_9FIRM/1024-1091      AC C0EGH7.1
#=GS R5QC51_9FIRM/472-536        AC R5QC51.1
#=GS A0A087A509_9BIFI/1052-1115  AC A0A087A509.1
#=GS U2T5L8_LEIAQ/954-1017       AC U2T5L8.1
#=GS A0A139PD45_9STRE/1321-1387  AC A0A139PD45.1
#=GS A0A0U1B0U6_9MYCO/1131-1197  AC A0A0U1B0U6.1
#=GS A0A168REA7_9MOLU/1162-1229  AC A0A168REA7.1
#=GS L0KXQ1_METHD/129-200        AC L0KXQ1.1
#=GS A0A087ECH4_9BIFI/902-969    AC A0A087ECH4.1
#=GS W1Q196_ABIDE/1866-1934      AC W1Q196.1
#=GS C0EA71_9FIRM/1546-1610      AC C0EA71.1
#=GS R6DWN1_9FIRM/1097-1161      AC R6DWN1.1
#=GS Q7NAP0_MYCGA/163-236        AC Q7NAP0.1
#=GS D3DEI4_MYCGA/82-146         AC D3DEI4.1
#=GS W1Q196_ABIDE/1171-1246      AC W1Q196.1
#=GS C0EHW2_9FIRM/809-875        AC C0EHW2.1
#=GS C0EGC6_9FIRM/1012-1075      AC C0EGC6.1
#=GS C0EI63_9FIRM/1361-1409      AC C0EI63.1
#=GS C0EAA0_9FIRM/1845-1911      AC C0EAA0.1
#=GS C0EHJ5_9FIRM/1457-1522      AC C0EHJ5.1
#=GS B1BYS5_9FIRM/1711-1774      AC B1BYS5.1
#=GS R2T0Z4_9ENTE/237-299        AC R2T0Z4.1
#=GS C0EAJ3_9FIRM/1584-1650      AC C0EAJ3.1
#=GS A0A081NTU4_9BACL/511-582    AC A0A081NTU4.1
#=GS W1Q196_ABIDE/828-902        AC W1Q196.1
#=GS A0A139NNV1_9STRE/1393-1460  AC A0A139NNV1.1
#=GS A0A0Q9Y3S3_9BACI/103-165    AC A0A0Q9Y3S3.1
#=GS E7G646_9FIRM/1629-1691      AC E7G646.1
#=GS R7HXE8_9CLOT/914-976        AC R7HXE8.1
#=GS D4CM03_9FIRM/962-1013       AC D4CM03.1
#=GS C0ECP3_9FIRM/1207-1270      AC C0ECP3.1
#=GS A0A0A7G287_9CLOT/1910-1973  AC A0A0A7G287.1
#=GS R5QB74_9FIRM/1599-1664      AC R5QB74.1
#=GS V9H2F0_9CLOT/2044-2107      AC V9H2F0.1
#=GS EBH_STAEQ/2155-2223         AC Q5HPA2.2
#=GS A0A0D5ZIP1_9MOLU/960-1025   AC A0A0D5ZIP1.1
#=GS L1Q4I7_9CLOT/1376-1438      AC L1Q4I7.1
#=GS E1L2L3_9ACTN/374-440        AC E1L2L3.1
#=GS C0EGF0_9FIRM/269-335        AC C0EGF0.1
#=GS B1BZX3_9FIRM/1367-1430      AC B1BZX3.1
#=GS S6EIU5_9CLOT/1793-1855      AC S6EIU5.1
#=GS A0A0J1GBA6_9FIRM/1530-1593  AC A0A0J1GBA6.1
#=GS R5Q9W5_9FIRM/1391-1453      AC R5Q9W5.1
#=GS D6S5D4_9LACO/955-1022       AC D6S5D4.1
#=GS D6S6B0_9LACO/2176-2243      AC D6S6B0.1
#=GS R6PEW3_9CLOT/2005-2068      AC R6PEW3.1
#=GS A0A087ECH4_9BIFI/38-105     AC A0A087ECH4.1
#=GS L1Q2N3_9CLOT/1640-1706      AC L1Q2N3.1
#=GS A0A0J1G477_9FIRM/908-961    AC A0A0J1G477.1
#=GS C0Z8W3_BREBN/119-184        AC C0Z8W3.1
#=GS C0EJA1_9FIRM/51-108         AC C0EJA1.1
#=GS C0EI61_9FIRM/1164-1227      AC C0EI61.1
#=GS Q833V2_ENTFA/1357-1420      AC Q833V2.1
#=GS R6UMN8_9FIRM/271-334        AC R6UMN8.1
#=GS R6QQA7_9CLOT/1740-1803      AC R6QQA7.1
#=GS C4FB73_9ACTN/1672-1734      AC C4FB73.1
#=GS E6U9D4_ETHHY/1453-1515      AC E6U9D4.1
#=GS S6EIU5_9CLOT/1583-1646      AC S6EIU5.1
#=GS D4M387_9FIRM/1474-1540      AC D4M387.1
#=GS C0EAQ7_9FIRM/1140-1204      AC C0EAQ7.1
#=GS B1C387_9FIRM/1414-1474      AC B1C387.1
#=GS E1L0K4_9ACTN/814-897        AC E1L0K4.1
#=GS J5GGL1_9FIRM/1476-1541      AC J5GGL1.1
#=GS C0EGF0_9FIRM/341-404        AC C0EGF0.1
#=GS R6V2H6_9FIRM/180-243        AC R6V2H6.1
#=GS R5QBC3_9FIRM/1761-1819      AC R5QBC3.1
#=GS B1C4V1_9FIRM/1111-1177      AC B1C4V1.1
#=GS R6Q007_9CLOT/996-1058       AC R6Q007.1
#=GS C0EI50_9FIRM/1240-1306      AC C0EI50.1
#=GS R9K3V3_9FIRM/221-284        AC R9K3V3.1
#=GS C0EIF1_9FIRM/1266-1331      AC C0EIF1.1
#=GS A0A133ZED0_9ACTN/2112-2164  AC A0A133ZED0.1
#=GS B1BZX2_9FIRM/1072-1135      AC B1BZX2.1
#=GS F3BBZ3_9FIRM/1533-1598      AC F3BBZ3.1
#=GS B1C4U2_9FIRM/1461-1524      AC B1C4U2.1
#=GS A0A087EKC0_9BIFI/1708-1771  AC A0A087EKC0.1
#=GS F3BB75_9FIRM/1956-2019      AC F3BB75.1
#=GS B1BZV7_9FIRM/702-764        AC B1BZV7.1
#=GS A0A0J1G2F1_9FIRM/1484-1548  AC A0A0J1G2F1.1
#=GS E1L279_9ACTN/11-78          AC E1L279.1
#=GS C0EIJ2_9FIRM/1597-1659      AC C0EIJ2.1
#=GS L1QE77_9CLOT/1579-1642      AC L1QE77.1
#=GS Q7NBD9_MYCGA/64-128         AC Q7NBD9.1
#=GS A0A0J1FZ32_9FIRM/509-577    AC A0A0J1FZ32.1
#=GS C0Z8W3_BREBN/47-112         AC C0Z8W3.1
#=GS Q8G751_BIFLO/1811-1874      AC Q8G751.1
#=GS B1BYS5_9FIRM/1778-1844      AC B1BYS5.1
#=GS C0EHJ7_9FIRM/1020-1089      AC C0EHJ7.1
#=GS A0A134AGW0_9FIRM/1836-1899  AC A0A134AGW0.1
#=GS R6CDJ9_9FIRM/702-768        AC R6CDJ9.1
#=GS C0EIJ6_9FIRM/1512-1577      AC C0EIJ6.1
#=GS F3BA09_9FIRM/1247-1310      AC F3BA09.1
#=GS D4CM03_9FIRM/1209-1274      AC D4CM03.1
#=GS L1Q4I7_9CLOT/1649-1712      AC L1Q4I7.1
#=GS E3D8E1_GARV3/2194-2258      AC E3D8E1.1
#=GS Q74JH9_LACJO/1055-1122      AC Q74JH9.1
#=GS F3BB75_9FIRM/1891-1953      AC F3BB75.1
#=GS D7UY97_LISGR/1288-1351      AC D7UY97.1
#=GS Q7NAP0_MYCGA/83-147         AC Q7NAP0.1
#=GS R9MD44_9FIRM/442-506        AC R9MD44.1
#=GS C0ECN8_9FIRM/1067-1132      AC C0ECN8.1
#=GS A0A0J1FY92_9FIRM/942-1009   AC A0A0J1FY92.1
#=GS A4VUI9_STRSY/1011-1078      AC A4VUI9.1
#=GS A0A133ZEX7_9ACTN/1194-1262  AC A0A133ZEX7.1
#=GS D6S697_9LACO/733-800        AC D6S697.1
#=GS E7G6U2_9FIRM/1467-1530      AC E7G6U2.1
#=GS U6Q456_9CLOT/1143-1205      AC U6Q456.1
#=GS C0EAY0_9FIRM/1072-1135      AC C0EAY0.1
#=GS EBH_STAEQ/2665-2739         AC Q5HPA2.2
#=GS R5QC51_9FIRM/334-400        AC R5QC51.1
#=GS A0A0R1WPI6_9LACO/315-383    AC A0A0R1WPI6.1
#=GS R5XWR4_9FIRM/1673-1741      AC R5XWR4.1
#=GS D6S5D3_9LACO/1026-1094      AC D6S5D3.1
#=GS Q5FIP8_LACAC/241-308        AC Q5FIP8.1
#=GS B1C4M7_9FIRM/1314-1381      AC B1C4M7.1
#=GS H1BKG0_9FIRM/779-843        AC H1BKG0.1
#=GS Q7NAP4_MYCGA/144-217        AC Q7NAP4.1
#=GS A0A095Z4C5_9FIRM/77-144     AC A0A095Z4C5.1
#=GS R5QS15_9FIRM/601-660        AC R5QS15.1
#=GS R6Q007_9CLOT/1134-1197      AC R6Q007.1
#=GS C0EGN8_9FIRM/1054-1121      AC C0EGN8.1
#=GS R6DWN1_9FIRM/449-517        AC R6DWN1.1
#=GS C0EAF8_9FIRM/1311-1375      AC C0EAF8.1
#=GS D6S6B0_9LACO/1223-1290      AC D6S6B0.1
#=GS F0Z2W1_9CLOT/825-888        AC F0Z2W1.1
#=GS B1C037_9FIRM/1402-1468      AC B1C037.1
#=GS C0EI61_9FIRM/1095-1160      AC C0EI61.1
#=GS C7RE21_ANAPD/1845-1912      AC C7RE21.1
#=GS R6EGW5_9FIRM/2045-2110      AC R6EGW5.1
#=GS B2TLL1_CLOBB/665-728        AC B2TLL1.1
#=GS C0EB37_9FIRM/833-899        AC C0EB37.1
#=GS B1C4U9_9FIRM/867-933        AC B1C4U9.1
#=GS A0A081NTU4_9BACL/165-236    AC A0A081NTU4.1
#=GS Q8G751_BIFLO/1735-1802      AC Q8G751.1
#=GS A0A0A3IGT2_9BACI/730-806    AC A0A0A3IGT2.1
#=GS C0EH55_9FIRM/1448-1511      AC C0EH55.1
#=GS A0A0J1IUK4_9FIRM/294-361    AC A0A0J1IUK4.1
#=GS D3DEJ8_MYCGA/62-126         AC D3DEJ8.1
#=GS EBH_STAA8/6506-6576         AC Q2FYJ6.1
#=GS B1C550_9FIRM/1468-1531      AC B1C550.1
#=GS S4GKI4_GARVA/631-703        AC S4GKI4.1
#=GS A0A0Q9Y5R2_9BACI/443-505    AC A0A0Q9Y5R2.1
#=GS Q7NBE0_MYCGA/82-146         AC Q7NBE0.1
#=GS A0A087ECH4_9BIFI/542-609    AC A0A087ECH4.1
#=GS R5QZJ3_9FIRM/1320-1383      AC R5QZJ3.1
#=GS R5R2Y5_9FIRM/1393-1456      AC R5R2Y5.1
#=GS F0YW90_9CLOT/1386-1453      AC F0YW90.1
#=GS D4J7K9_9FIRM/1560-1622      AC D4J7K9.1
#=GS U2Q023_9CLOT/98-163         AC U2Q023.1
#=GS U2Q023_9CLOT/161-229        AC U2Q023.1
#=GS C5NV36_9BACL/726-792        AC C5NV36.1
#=GS S6EI11_9CLOT/1561-1624      AC S6EI11.1
#=GS R6U802_9CLOT/417-479        AC R6U802.1
#=GS A0A0M2VRV1_9BACL/567-630    AC A0A0M2VRV1.1
#=GS EBH_STAEQ/2496-2563         AC Q5HPA2.2
#=GS B9DPH4_STACT/1222-1286      AC B9DPH4.1
#=GS C0EI48_9FIRM/556-619        AC C0EI48.1
#=GS A0A0B0I408_9BACL/622-677    AC A0A0B0I408.1
#=GS C0EGG1_9FIRM/193-256        AC C0EGG1.1
#=GS T0TIC2_9STRE/525-592        AC T0TIC2.1
#=GS B1C0F0_9FIRM/1556-1619      AC B1C0F0.1
#=GS A0A0Q9N768_9BACL/1649-1717  AC A0A0Q9N768.1
#=GS C0EDY6_9FIRM/1009-1076      AC C0EDY6.1
#=GS I7KH63_9LACO/1679-1745      AC I7KH63.1
#=GS D3DEI2_MYCGA/79-143         AC D3DEI2.1
#=GS B1C559_9FIRM/1876-1939      AC B1C559.1
#=GS D6S5D2_9LACO/617-684        AC D6S5D2.1
#=GS A0A0D4CKN9_9LACO/1095-1169  AC A0A0D4CKN9.1
#=GS F3BBJ0_9FIRM/1464-1527      AC F3BBJ0.1
#=GS A0A037Z2K9_CLOTT/582-653    AC A0A037Z2K9.1
#=GS R7G4E1_9FIRM/440-502        AC R7G4E1.1
#=GS A0A139T5W1_9FIRM/720-804    AC A0A139T5W1.1
#=GS A0A0D5ZJZ3_9MOLU/592-642    AC A0A0D5ZJZ3.1
#=GS B6GAA9_9ACTN/1565-1626      AC B6GAA9.1
#=GS A0A089L0Z7_9BACL/1463-1530  AC A0A089L0Z7.1
#=GS D4J7K9_9FIRM/1062-1124      AC D4J7K9.1
#=GS L1Q6I7_9CLOT/69-132         AC L1Q6I7.1
#=GS C4GAC6_9FIRM/1468-1534      AC C4GAC6.1
#=GS L1Q2N3_9CLOT/1778-1841      AC L1Q2N3.1
#=GS D6S6B0_9LACO/1871-1936      AC D6S6B0.1
#=GS F3BA09_9FIRM/1110-1175      AC F3BA09.1
#=GS L1Q2P5_9CLOT/1651-1713      AC L1Q2P5.1
#=GS W1Q196_ABIDE/1264-1332      AC W1Q196.1
#=GS F7KM67_9FIRM/1302-1365      AC F7KM67.1
#=GS R6DWN1_9FIRM/731-798        AC R6DWN1.1
#=GS D6S5D3_9LACO/1691-1758      AC D6S5D3.1
#=GS A0A089L0Z7_9BACL/1154-1224  AC A0A089L0Z7.1
#=GS M8E383_9BACL/350-415        AC M8E383.1
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B1BZX6_9FIRM/736-799                   .....................................DKSLLEELINQANG--...........--LN....KAN.Y..T.KA....SFDGLTKALNEA...................KAV.Y-....-.....-...EN......P......N...A........T........Q......K....E....VDNAKFTLEKAIAGLQ........................
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A0A0D5ZJ27_9MOLU/4285-4352             ...................................ad---ELEKLVNQSNTFV...........KESP....YVV.A..P.SD....KKNAYDQAINKG...................KEA.LN....-.....-...DL......E......N...K........T........A......K....E....IEQIVDQIKKAIKD--il......................
R6U802_9CLOT/348-414                   .....................................DKEKLKVLVEIVKDLL...........--ND....YSK.Y.iD.PT....SMAEMRELLGKA...................DEV.I-....-.....-...AD......D......N...A........T........V......D....D....VSNAIKDVDKKIDEL-k.......................
K8ET84_CARML/393-456                   .....................................DKTALLSALERANSID...........----....RSL.Y..T.VE....SLAILDQVIESL...................QGI.A-....-.....-...SD......E......N...A........T........Q......E....D....VNSSVALIDEAVNQL-v.......................
A0A0J1GD37_9FIRM/108-176               ..................................qkv---GLKTAIDGAKAIL..........eDGAE....LSG.Y..T.PE....SIEAVKAALAEA...................EKI.F-....-.....-...AD......I......S...A........D........A......Q....T....VNQASRNLMDAVTN--mk......................
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V1CRC4_9FIRM/437-502                   .....................................DKTKLKAAIDGEKETF...........DDVN....AGV.Y..K.PV....GAAEYLKKYNKA...................LKV.L-....-.....-...ED......P......D...A........T........Q......E....T....VDKATRDLLNSKN---l.......................
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C0E8Z7_9FIRM/1267-1333                 .....................................DKKLLQQVLAAAEA--...........--LD....LSS.Y..S.EV....SVEAFQAAYAQA...................SAI.AA....D.....E...SL......S......T...D........E........Q......D....Q....VDEAVNMLSEAIKNL-s.......................
A0A139PD45_9STRE/1465-1532             ..................................fas----LKKLVDDEGHYQ..........aISNK....FIY.A..S.DQ....IKAAYLDAYAQA...................KAV.L-....-.....-...AN......P......G...A........S........Q......E....E....VKEAIAQLKAAKKKLD........................
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F0Z608_9CLOT/4-46                      ...................................es----------------...........----....---.-..-.--....VQKLFAEAIAEG...................EAI.M-....-.....-...EK......E......D...A........S........K......E....D....VLGACVKLMKAIQALD........................
F3BBR4_9FIRM/1656-1719                 ...................................vr--KALEERVKFAQT--...........--IT....SNG.Y..T.AD....SYSAFKAALKAA...................EET.L-....-.....-...AN......E......N...A........T........D......A....Q....LQSALDNLNTGINGL-k.......................
J5W865_9FIRM/1567-1628                 ..................................rsv----LRDKIEEYKN--...........--IN....LDL.Y..K.LD....TKLEFIRALREA...................ESV.L-....-.....-...KD......N......L...A........L........Q......D....K....IDKAVEKLETAKNNL-........................
D4M2N0_9FIRM/983-1045                  ...................................tt--TELEAAIAKAEALK...........----....EAE.Y..T.AE....SWASMQMELQEA...................KDE.LK....N.....P...--......-......-...K........T........Q......A....T....VDEAVSHLNAAVEAL-v.......................
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R9MA99_9FIRM/819-879                   ................vlqeiletakllkeedyvsgy----------------...........----....---.-..-.--....--EELQEAIAEA...................QAI.C-....-.....-...DD......I......N..hA........E........E......T....K....VKAALKRLQDAIDALQ........................
Q7NB25_MYCGA/52-116                    ....................................t-KRQLNNLIDSQPTTL...........--QM....YED.Y..K.NI....R-NTLNAAYQAA...................RII.S-....-.....-...DS......N......N...S........T........P......E....Q....LEAAIVTLRNAIG---kas.....................
B1BZX2_9FIRM/1206-1269                 ....................................n-KDLLEELINKAEG--...........--LN....GAN.Y..T.KA....TFDGLTKALNEA...................KAV.F-....-.....-...DD......P......D...A........T........Q......E....E....VDNAKDVLAKALAGLQ........................
R5Q9W5_9FIRM/1469-1532                 .....................................DKSKLQELYNKYKGIK...........----....ADG.Y..T.AE....SWTAFAEARTEA...................ETV.L-....-.....-...AN......E......K...A........T........Q......E....K....VDKAAENLEKAFKSL-k.......................
Q7NBE3_MYCGA/48-112                    ...................................tr--NSLATLLNGQTNTL...........--SS....YND.Y..A.KL....K-QNLMAAYSAA...................TTV.Q-....-.....-...NN......E......N...A........S........L......E....N....LRDAVRQLKNALNTAN........................
H1BJ97_9FIRM/118-181                   .....................................DKAELKNALDEAKA--...........--IQ....AEG.F..T.SA....SYAKLQKAIKAA...................EKV.Y-....-.....-...AD......A......A...A........S........Q......D....D....VKVQVKNIQKAIQSL-e.......................
I7KH63_9LACO/1600-1664                 .....................................ARRELRAKLDEARQL-...........--GT....SGK.Y..T.HE....SAQNLAQARQKA...................AQV.L-....-.....-...RN......K......D...A........K........L......A....E....LQEALQELTKAVQDL-k.......................
F7KM67_9FIRM/1112-1177                 .....................................DKSKLKERLDVASLFD...........--GK....EAD.Y..T.AE....SYQALQSAKAAA...................QLV.Y-....-.....-...DK......V......D...A........T........Q......P....E....VDEEYQKLDAAIK---gmk.....................
A0A087ECH5_9BIFI/33-100                ....................................d-TTALQAQVDKDADVK...........ALTG....WAN.A..S.DN....EKTAYNNALDAA...................NTV.L-....-.....-...TN......P......D...A........T........Q......D....Q....VNEALKNLQDAANA--ia......................
R6LRK9_9FIRM/155-219                   ....................................d-TTALSGAIASAEALK...........--DK....EED.Y..T.AE....SWSNMQEKLTAA...................KNV.FT....A.....K...--......-......-...E........S........Q......A....T....VDAAAKALTDAMNALE........................
A0A134AGW0_9FIRM/1914-1977             .....................................AKDALGAAIQEAKNKL...........--ND....GKK.Y..T.AE....TKSAVEKAIAKA...................EKV.LA....G.....K...D-......-......-...-........-........K......A....A....MNKAKGDVEK------aaaglk..................
R6UD80_9CLOT/301-366                   ..................................aii---KLQQTVDNAQKYL...........--DS....SDL.Y..T.EN....TISALQKAVNNA...................NDL.I-....-.....-...DQ......N......S...W........N........Q......S....A....VASSDAAVSSAVA---mlv.....................
A0A0D1Y4D7_ANEMI/805-870               .....................................DKSALQAKVTEING--...........ENLK....EAN.Y..T.SA....SWKTLQDALTEA...................NKI.L-....-.....-...TD......P......N...A........T........Q......T....Q....VKAALDALTSARNGL-s.......................
C8PC68_9LACO/1181-1241                 .....................................AKKKLESLIKEDPTKD..........kTTTT....KTA.Y..D.NV....K-KTAEQLLTKA...................QNL.I-....-.....-...ED......D......N...A........T........Q......D....D....VDAILENL--------l.......................
A0A134AGW0_9FIRM/1758-1821             .....................................AKAALTKAIAAAEAKL...........--KD....GKD.Y..T.AD....SKKAVEGKVAAA...................KEA.LK....G.....N...--......-......-...-........N........V......E....A....MNAAKANLENAVKAL-k.......................
C6D7A5_PAESJ/1610-1681                 .....................................DKTALRAAIATADSRLtg.......aiEGSF....LGQ.Y..A.SG....SKAQLQTKLAAA...................NAA.L-....-.....-...AD......P......T...L........S........Q......A....G....IGEAAAQLTAAISEF-d.......................
A0A0Q9YID5_9BACI/141-203               ...................................dt--GELSKLINHAKT--...........--YE....KDK.Y..T.ET....SYGALQQAISHA...................EAV.VQ....T.....A...--......-......-...N........T........Q......N....E....VTEAITHLQKAINGL-e.......................
A0A0B0I408_9BACL/916-983               .....................................DKTELKSLINQARDML..........dH-QE....QYE.A..T.PE....QWKALKDALAAA...................QTA.A-....-.....-...DD......K......S...A........T........E......G....D....IKAASERLKTALDTF-n.......................
A0A0J1FY43_9FIRM/823-886               ....................................s-KTALNAKIAEAKGIR...........Q---....-GN.Y..T.DE....SYKALQNAIVKA...................QEL.S-....-.....-...NK......T......D...A........T........Q......Q....Q....VNDLVSALTNAIKNL-k.......................
E0ID12_9BACL/619-682                   .....................................DKSALDAKIEAGQQLE...........Q---....-ND.Y..T.PA....SWSLFESALITA...................KEA.S-....-.....-...FS......N......S...A........S........K......A....E....VDQALEGLTKSMAAL-v.......................
B1C5E0_9FIRM/1918-1981                 .....................................DKTELIKLVEEYSK--...........--LE....ENN.Y..T.TA....SWEVFKGALDAA...................IAV.R-....-.....-...DD......E......N...A........L........E......Y....E....VKEALNNLKD------gyaqlv..................
E7G6U2_9FIRM/1396-1462                 .....................................DKSQLESIILKAEKIT...........E-ET....LKK.L..D.TK....IVQEFKSALQKA...................KQI.Y-....-.....-...NN......G......E...V........T........Q......L....E....VNNAITLLSEAIDYL-k.......................
D6S6B0_9LACO/2091-2157                 ...................................fd---KLIAAIAKAEEAK...........TSEK....YVY.E..S.DA....NKEAFDEMLDKA...................KAE.M-....-.....-...GQ......T......N...V........S........Q......K....T....VDQITDELIKAINSLT........................
Q897I5_CLOTE/1236-1299                 .....................................DKTKLEEIINKAEKID...........----....LEG.K..T.EK....SIKTLNESISKS...................KEI.L-....-.....-...SK......H......E...L........T........Q......K....E....VDNAVKVVEMAIKNL-e.......................
V9HES6_9CLOT/1484-1546                 .....................................DKSKLEDLINKAKAVD...........----....LSK.Y..T.EK....SANELKIQLARA...................SEV.F-....-.....-...AN......E......E...A........T........Q......E....E....INKATRSLDTALNDL-........................
U7UEJ5_9FIRM/486-532                   ....................................p----------------...........----....--Q.Y..T.YQ....SNMMYVNAYNSL...................MSL.L-....-.....-...TK......P......N...V........T........D......M....Q....VKSAIDNLKAAVEGL-k.......................
L1QE77_9CLOT/1791-1854                 ....................................s-KDKLEELINKAESLD...........----....SNK.Y..T.VA....SFKAVEKALEEA...................NKV.F-....-.....-...AS......E......D...A........T........S......E....E....IAKAEANLRNAMNSLQ........................
E6U9D8_ETHHY/1624-1688                 ...................................de--TALDTLVDTAGQI-...........--SD....SNS.Y..T.VA....SWDTFQSALQAA...................KGV.Q-....-.....-...QE......L......N...P........T........Q......Q....E....IDSAYNVLDAAQKGL-a.......................
Q7NBD5_MYCGA/187-260                   .....................................AYNNLKETLKEEKTNLd........slANEN....YAA.I..R.TN....LNSLYEKANTIV...................TAT.LD....P.....A...TG......N......I...P........Q........V......M....S....VTQANQDITNATSKL-v.......................
C0ECP1_9FIRM/1172-1235                 ....................................d-KSVLESVLADAAGID...........T---....-AA.Y..T.AA....SIEAFQTAYNKA...................MTI.N-....-.....-...DN......A......N...A........T........Q......A....E....VDEAIGSLKNAIDGL-v.......................
C0EC17_9FIRM/1182-1248                 .....................................DKTQLEVVVRQATKIA...........V-DL....EDK.Y..V.TA....GQDAFKAALDKA...................NET.L-....-.....-...LN......P......D...A........T........Q......A....Q....IDQAVLDLIDAM----lnlr....................
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Q7NAN8_MYCGA/161-234                   .....................................AYDALKQTITSEEMSLn........qlMDAN....FET.I..K.NH....ISNLYKQGKDII...................TAT.LD....P.....T...TG......D......G...P........Q........A......M....V....VNQTNEAIVNATSK--ie......................
F7KWA1_9FIRM/833-895                   .....................................DKSELTKLISEVKYM-...........---K....PGN.Y..T.DE....SYANLRTAFEQA...................KKD.FE....E.....A...--......-......-...D........T........K......E....K....VSAAIEKLQEAIDAL-k.......................
A0A0J1J972_9FIRM/606-671               ...................................df--SALNAKINSARAIN...........--NN....NGI.Y..T.KS....SFDALQNAIAKA...................QAV.A-....-.....-...GN......K......N...S........K........Q......A....D....VDQALQELQNAVNGL-v.......................
R6BTC3_9FIRM/30-92                     ..................................kad--------VQKAYNTY...........VNYK....SED.Y..T.GK....TWTFFADALANA...................KKV.L-....-.....-...DN......A......D...S........T........A......A....A....YSQAYTNLTNVAAQL-e.......................
U7UMZ8_9FIRM/300-362                   ....................................e-KEALTKEIAAAKEIV...........K---....-GK.K..T.DE....AFSKLKAAIAAA...................EKV.L-....-.....-...-G......E......A...T........E........Q......T....Q....LDEAVKALKTAVKAF-k.......................
C0EGE4_9FIRM/1335-1398                 ....................................d-KGVLEAVLAEANAID...........----....LSA.Y..S.EA....DLAAFNAAKAAA...................EAV.Y-....-.....-...ND......V......N...A........E........Q......D....A....ADKAVSDLQAAIASLT........................
E3D767_GARV3/1109-1189                 ..............kdklnaaiaehgkvntgdadkqg------------DEKLk.........tADPT....YQN.S..T.SD....ERTAYDNAVKKA...................NEL.S-....-.....-...KD......P......N...A........S........Q......K....D....VNKAIEDLKKAKDALD........................
L1Q934_9CLOT/1930-2001                 .....................................DKTDLTRLVANAREVI...........--AK....LSD.YegT.EE....LVSNLEAIITNA...................EKL.I-....-.....-...ND......D......N...A........S........A......EevmdQ....IKELAKEVENAKEKL-e.......................
R6EP30_9FIRM/3-68                      ...................................dr--SGLSEKISEAEKLS...........--VS....ENI.Y..T.EE....SMEVLKQAINAA...................KDI.Y-....-.....-...AD......P......N...A........S........Q......E....D....IDAQVSALQAAIDSL-e.......................
B1BZG6_9FIRM/1870-1933                 .....................................DKSLLEDLINQANG--...........--LN....GAN.Y..T.KA....TFDGLTKALDEA...................KAV.Y-....-.....-...EN......P......D...A........T........Q......K....E....VDNAKDVLAKAIAGLQ........................
R5R0K4_9FIRM/1874-1937                 .....................dkteleklyqdtlgkv----------------...........----....EKD.Y..T.AS....TWKVFVESQKAA...................AEV.L-....-.....-...AK......E......D...A........T........K......E....E....ILEAYNNLAAAVNGL-k.......................
C5NYF6_9BACL/1575-1641                 .....................................DKKELASEVEKNGDLT...........SQDS....FKD.A..D.EV....VKKEYKEALKVA...................NLV.L-....-.....-...SN......A......N...A........K........Q......D....E....VNNALENLKKAS----ekv.....................
R7B6W4_9ACTN/1726-1789                 ....................................d-KLALRTAIDNAKA--...........--IE....KGN.H..T.DT....AWNALQEAIDDA...................EGI.F-....-.....-...NT......L......E...A........R........Q......S....E....VDASVRSLNTAVT---lfn.....................
J5W865_9FIRM/1935-2000                 .....................................DKEELIAEVDSSKEIE...........--LK....LSD.Y..E.NI....GQAEFKEALKRA...................EEV.L-....-.....-...NK......S......K...I........E........K......G....D....IKKALEELKEKREAL-k.......................
R5QDP0_9FIRM/1830-1892                 ......................telqaaydlyagkdl----------------...........----....-SI.Y..T.QD....SKTVLEEALKEA...................EKV.LK....-.....-...LG......E......N...A........V........K......E....D....VNEALEKLQKAIEGL-e.......................
A0A134AGT3_9FIRM/1779-1841             .....................................AKIALKEAIEKAEAKL...........A---....AAS.Y..T.AE....SKGKLEAAIASA...................KAA.LE....G.....D...--......-......-...-........N........V......T....D....MNRAITSVFDAMDQL-v.......................
B1C0B0_9FIRM/1457-1520                 .....................................DKSLLEDLINQANR--...........--LN....KAN.Y..T.KA....SFDGLTKALDEA...................KVV.F-....-.....-...EN......P......D...A........T........Q......E....E....VDNAKDVLAKALAGLQ........................
A0A0J1FY92_9FIRM/1083-1147             .....................................DKAELKNALDKANEII...........--AN....SGK.Y..L.ED....TISGLQAVITEA...................QTV.Y-....-.....-...DS......G......D...A........D........T......E....K....VGEVLKKLVNE-----ilka....................
Q7NB24_MYCGA/63-127                    ...................................tr--NQLSGLLNKQANQV...........--GM....YNE.Y..K.QI....Q-AGLKSAYEAA...................KAV.V-....-.....-...DN......T......N...S........T........S......E....Q....LNEAKTALENAISQA-e.......................
B1C383_9FIRM/167-230                   ....................................n-KDLLKDLINEANG--...........--LN....AAN.Y..T.KA....SLDGLTKALNEA...................KAV.F-....-.....-...EN......S......N...A........T........Q......E....E....VDNAKDVLEKAINSL-e.......................
F9UKR6_9MOLU/5398-5455                 ....................................s-MATLAQLNDAKTAVK...........DSDT....YAK.A..S.EE....SKAKYEKLTSAA...................DEL.I-....-.....-...KN......T......N...P........S........A......D....K....----------------legtdi..................
R5QS73_9FIRM/1709-1772                 .....................................DKNNLISIFNTALK--...........--LD....KEK.Y..T.SE....SLTKVEALLEKV...................ESI.I-....-.....-...DD......E......N...A........A........Q......A....E....VDEMYDQLHQALDQL-v.......................
G1WHV9_9ACTN/110-173                   .....................................DKSMLKSSIEAYTS--...........--LS....GND.Y..T.PE....TFQALLEALDAA...................KKV.L-....-.....-...DD......D......K...A........T........Q......D....D....VDDAHSKLVSAHSSL-k.......................
D6S5D4_9LACO/72-139                    ....................................n-KKPLEESIALAKDLQ...........NTDV....YNN.A..S.DA....QREALSEALSEA...................EGQ.D-....-.....-...AD......P......S...A........T........Q......T....N....VDAAKAKLDQAFEA--fs......................
I3WGL8_BIFBI/1718-1781                 ....................................p-KADLRKEVESASKLD...........----....EKD.Y..T.AD....SWKVFAAALDNA...................KAV.L-....-.....-...ED......K......D...A........T........E......A....Q....ISGALTTLKSATAAL-a.......................
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A0A0Q9YID5_9BACI/518-580               ....................................d-TTELEKLIAQAKT--...........--YG....KED.Y..T.DT....SYAVLQKAIRQA...................ETV.LE....D.....E...--......-......-...K........T........E......E....T....IAEATIQLRKAIAGL-g.......................
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R6PWU0_9CLOT/1979-2041                 .....................tdlqaaydmyegkdls----------------...........----....--I.Y..T.ED....TRKALEEALKEA...................KEI.LD....-.....-...LG......E......N...A........V........K......E....L....VDAALEKLNAAIEGL-e.......................
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B1C336_9FIRM/1267-1333                 .....................................DKTALKIAVDLANAIT...........D-KD....LEK.V..I.PV....VANEFIAARDEA...................NAI.Y-....-.....-...ND......A......S...A........T........Q......D....E....VNAAFDILASAM----hmld....................
E3D767_GARV3/2312-2358                 ............................fiigkaadl----------------...........----....---.-..-.--....--AEYQQALNDA...................DSV.L-....-.....-...KD......P......N...A........T........Q......D....Q....VNQALRRLRDAKQKL-........................
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C0Z8W3_BREBN/191-256                   ....................................y-KRELRAKVDEIEDKD...........--LD....KDD.Y..T.RS....SWRDLEDALKQA...................WDV.I-....-.....-...DD......P......H...A........T........Q......S....E....VDDALYDLKKAWRDL-e.......................
#=GC SS_cons                           .....................................--HHHHHHHCCHHHHHCC.......--BSSC....TTC.B..-.TT....HHHHHHHHHHHH...................HHH.H-....-.....-...TS......T......T...T........T........C......C....C....HHHHHHHHHHHHHHH-C.......................
#=GC seq_cons                          ......................................hptLpphlspspt................t....hss.Y..o.pp....shpshpsAlspA...................psl.h...............ss......t......s...A........o........Q......p....p....VspAhssLpsAhpsL.h.......................
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