GenomeNet

Database: Pfam
Entry: FTZ
LinkDB: FTZ
Original site: FTZ 
#=GF ID   FTZ
#=GF AC   PF03867.11
#=GF DE   Fushi tarazu (FTZ), N-terminal region
#=GF AU   Finn RD
#=GF SE   DOMO:DM07486;
#=GF GA   25.00 25.00;
#=GF TC   29.00 29.00;
#=GF NC   24.00 18.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11592991
#=GF RT   Segmentation gene product Fushi tarazu is an LXXLL
#=GF RT   motif-dependent coactivator for orphan receptor FTZ-F1. 
#=GF RA   Suzuki T, Kawasaki H, Yu RT, Ueda H, Umesono K; 
#=GF RL   Proc Natl Acad Sci U S A 2001;98:12403-12408.
#=GF DR   INTERPRO; IPR005567;
#=GF CC   This region contains the important motif (LXXLL) necessary for
#=GF CC   the interaction of FTZ with the nuclear receptor FTZ-F1. FTZ is
#=GF CC   thought to represents a category of LXXLL motif-dependent
#=GF CC   co-activators for nuclear receptors.
#=GF SQ   11
#=GS B4GEM3_DROPE/1-284  AC B4GEM3.1
#=GS B2ZIC3_DROSE/1-251  AC B2ZIC3.1
#=GS B3M0P9_DROAN/1-260  AC B3M0P9.1
#=GS FTZ_DROME/1-248     AC P02835.2
#=GS FTZ_DROME/1-248     DR PDB; 2XHS B; 1-9;
#=GS B4NAA7_DROWI/1-267  AC B4NAA7.1
#=GS B4QYX9_DROSI/1-251  AC B4QYX9.1
#=GS B4K6G3_DROMO/1-260  AC B4K6G3.1
#=GS B4JGL9_DROGR/1-301  AC B4JGL9.1
#=GS Q296U9_DROPS/1-280  AC Q296U9.3
#=GS F5HK01_ANOGA/1-268  AC F5HK01.1
#=GS B4LYV4_DROVI/1-281  AC B4LYV4.1
B4GEM3_DROPE/1-284             .........MATTNSQSHYY-.AD..NMYNMYHHHtahSLP...PTYYDN....--SYYQSATqSTASQWQPSPAGYQGNYGAAYGVQESYSDSCYYAQSSYSpIDATVPQIPAVPAMP...................aSQPEP.................iLAASPVKTLKRKAE-.....DAAAVIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTFETVKKSPatVPAQIKASSSPAPSYEQEYVAAPTP...........SASEDVDYLDVYSPQSQKn....hKNGEYvaGTPPPLASTPATPTSI..VE......GISTPPQSPGVKSgta.snvSHEINHRIVTAANSgvA...ADFNWSHIEESLA................
B2ZIC3_DROSE/1-251             .........MATTNSQSHYSY.ADnmNMYNMYHPH...SLP...PTYYDNs..gSNAYYQNSS.-----------TYQ--SYQGYYPQESYSESCYYYN----.NQEQV-TTQTVPPL-....................-QPTT..................---PPPKATKRKAEE.....DAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAP.aVTTKVA--ASPAPSYEQEYVTVPTP...........SASEDVDYLDVYSPQSQTq...klKNGDF..ATPPP-----TTPTSLspVE......GISTPPQSPGEKSss...avSQEINHRIVTAPNG..A...GDFNWSHIEETLA................
B3M0P9_DROAN/1-260             .......ma-----ANSHYNYsAEnmNMYNMYHHH...SLP...PTYYDNa..sGNGYYQASS.-----------SYQ--SYQGYYPQENYSENCYYYG----.QQEQVPQVPEVPQVT....................QQPAT..................---PPPKAAKRKAEE.....DAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTLEQVKKTP.aPTTKATAAASPAPSYDQEYVTAPTP...........STSEDVDYLDVYSPQSAQsqslklKNGDF..ATPPP-----TTPTSLppVE......GLSTPPQSPGEKSssassavSQEINHRIVTGPSN..A...NDFNWSHIEETLA................
FTZ_DROME/1-248                .........MATTNSQSHYSY.ADnmNMYNMYHPH...SLP...PTYYDNs..gSNAYYQNTS.-----------NYQ-----GYYPQESYSESCYYYN----.NQEQV-TTQTVPPV-....................-QPTT..................---PPPKATKRKAED.....DAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAP.aVSTKVT--ASPAPSYDQEYVTVPTP...........SASEDVDYLDVYSPQSQTq...klKNGDF..ATPPP-----TTPTSLppLE......GISTPPQSPGEKSss...avSQEINHRIVTAPNG..A...GDFNWSHIEETLA................
#=GR FTZ_DROME/1-248     SS    .........XXXXXXXXXXXX.XXXXXXXXXXXXX...XXX...XXXXXXX..XXXXXXXXXX.-----------XXX-----XXXXXXXXXXXXXXXX----.XX-HH-HHHT-XXX-....................-XXXX..................---XXXXXXXXXXXX.....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXX--XXXXXXXXXXXXXXXXX...........XXXXXXXXXXXXXXXXXXX...XXXXXXX..XXXXX-----XXXXXXXXXX......XXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXX..X...XXXXXXXXXXXXX................
B4NAA7_DROWI/1-267             .......ma----ASHSHYYTaAD..SMYNMYHHHhhlAAPtstSTYYDN....----YQNYQsNTGSASSWQSASYQQSYSNSYTNQEQFTDNCYYSG--YSpEQMPVYQQQEVPSVPeatp............leslALPP-..................--PSPPKSLKRKAEEtitkdTAAAVIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTFESVKKAA..VSTKIT--SSPAPSYEPDYVAAPTP...........TASEDVDYLDVYSPKTS-......KNG--..-TPPP-STTPATPTSL..VE......GISTPPQSPKEKN.......QEQINHRIVT----..A...NDFDWSHIEES--qi..............
B4QYX9_DROSI/1-251             .........MATTNSQSHYSY.ADnmNMYNMYHPH...SLP...PTYYDNs..gSNAYYQNSS.-----------TYQ--SYQGYYPQESYSESCYYYN----.NQEQM-TTHTVPPV-....................-QPTT..................---PPPKATKRKAEE.....DAASIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAP.aVTTKVA--ASPAPSYEQEYVTVPTP...........SASEDVDYLDVYSPQSQTq...klKNGDF..ATPPP-----TTPTSLppVE......GISTPPQSPGEKSss...avSQEINHRIVTAPNG..A...GDFNWSHIEETLA................
B4K6G3_DROMO/1-260             .........MAATNTH---YY.AD..SMYNMYHH-...ALP...PTYYDNt.ssSSSYYQ---.---SNQSWQPASYQPSSYAHYS-QESYSESCYYANYHHQ.QQQQTQQPQQ-----....................QQP--..................FSPAPAKSRKRKAEE.....SAADIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTIEHVKR--..-PSKSSSAGELSPCYEQDY-AVPTPstqqthmspqrSTGEDVDYLDVYSPRKPA......KHGDF..VTPPPAATTPVDGLGL.gLG.....iGISTPPQSPAEKS.......-NEINHRIVTAANA..S...NEFNWSHIEETIA................
B4JGL9_DROGR/1-301             .........MAATNTHSHSYY.AD..SMYNMYHH-...GLP...PTYYDN....SNSYYQQSN.STSSCSSW-PTSYQPSSYAQYG-QESYGESCYYSNYQHQ.HQLQQQQQQQTMTMPapaa............lphyQAPAPvsvpvp.....apaaatvTTPAPLKSRKRKAEE.....SAADIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTFEQVKK--..-PNRSSSAGELSPCYEQDY-AVPTPstqqthmspqrSSSEDVDYLDVYSPRKQA......KHGDF..VTPPPAATTPTATTPAslVDgigigiGISTPPQSPAEK-.......-NEINHRNVTAASS..SssnNEFNWSHIEETLA................
Q296U9_DROPS/1-280             .........MATTNSQSHYY-.AD..NMYNMYHHHtahSLP...PTYYDN....--SYYQSATqSTASQWQPSPASYQSNYGAAYGVQESYSDSCYYAQSSYSpIDATV---PQIPAVP....................AMPEP.................iLAASPVKTRKRKAE-.....DAAAVIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTFETVKKSPatVPAQIKASSSPAPSYEQEYVAAPTP...........SASEDVDYLDVYSPQSQKn....hKNGEYvaGTPPPLASTPATPTSI..VE......GISTPPQSPGVKSata.snvSHEINHRIVTAANSgvA...AEFNWSHIEESLA................
F5HK01_ANOGA/1-268             msipqsqll------------.--..---------...---...----QN....-SQYAQQSQqEIQNISSISSSAYGYSATAQYNHDEQFSSNSLHTR-HHQ.LENYGNQFDSYYGYPyqttahyslcgaqehleeyfY---KpteversnvekrscekscET-IKPPAMKRKISE.....KETN---DNEKDSPALRALLTNPAKKLKYNPHYAHSMTNESSRRI..EATIGYNNGFLSPAASDRIVPDIVPls.......pnKTDDSIDSLLDNSSKQDI......VTMQC..VDYTLNSLRQITATPK..YD......GVSTPPLSPKNME.......--------------..-...-------------saissqgvenhpkess
B4LYV4_DROVI/1-281             .........MAATNTHSHSYY.AD..SMYNMYHH-...ALP...PTYYDNtssgSSSYYQ-SN.SMASTASWQPANYQAGSYVQYG-PESYSESCYYANYQQT.-TLPQPEPAAVPQYHpt................avAEPFTk................aNSPAPVKSRKRKAEE.....SAAEIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTTIEPVKK--..-PSKSSSAGELSPCYEQDY-AVPTPstqqthmspqrSTSEDVDYLDVYSPHKQA......KHGDF..ITPPPAATTPATPASL..VDg....iGISTPPQSPAEKS.......-HEINHRIVTAATG..N...NEFNWSHIEETLA................
#=GC SS_cons                   .........XXXXXXXXXXXX.XXXXXXXXXXXXX...XXX...XXXXXXX..XXXXXXXXXX.-----------XXX-----XXXXXXXXXXXXXXXX----.XX-HH-HHHT-XXX-....................-XXXX..................---XXXXXXXXXXXX.....XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXX--XXXXXXXXXXXXXXXXX...........XXXXXXXXXXXXXXXXXXX...XXXXXXX..XXXXX-----XXXXXXXXXX......XXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXX..X...XXXXXXXXXXXXX................
#=GC seq_cons                  .........MAsTNopSHY.Y.AD..sMYNMYHHH...uLP...PTYYDN....usuYYQsos....s..p..ssoYQ.suhsuYssQESYSESCYYss...p.pQtps.p.ppVPsh.....................tpPts.....................sPsKupKRKAEE.....cAAuIIAAVEERPSTLRALLTNPVKKLKYTPDYFYTThEpVKKss..ssoKssssuSPAPSYEQ-YVssPTP...........SuSEDVDYLDVYSPpoQt......KNGDF..sTPPP.u.p.sTPTSL..VE......GISTPPQSPuEKS.......ppEINHRIVTAssu..A...s-FNWSHIEETLA................
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