GenomeNet

Database: Pfam
Entry: FTZ
LinkDB: FTZ
Original site: FTZ 
#=GF ID   FTZ
#=GF AC   PF03867.12
#=GF DE   Fushi tarazu (FTZ), N-terminal region
#=GF AU   Finn RD
#=GF SE   DOMO:DM07486;
#=GF GA   25.00 25.00;
#=GF TC   30.60 30.60;
#=GF NC   23.60 19.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11592991
#=GF RT   Segmentation gene product Fushi tarazu is an LXXLL
#=GF RT   motif-dependent coactivator for orphan receptor FTZ-F1. 
#=GF RA   Suzuki T, Kawasaki H, Yu RT, Ueda H, Umesono K; 
#=GF RL   Proc Natl Acad Sci U S A 2001;98:12403-12408.
#=GF DR   INTERPRO; IPR005567;
#=GF CC   This region contains the important motif (LXXLL) necessary for
#=GF CC   the interaction of FTZ with the nuclear receptor FTZ-F1. FTZ is
#=GF CC   thought to represents a category of LXXLL motif-dependent
#=GF CC   co-activators for nuclear receptors.
#=GF SQ   12
#=GS B4GEM3_DROPE/1-284      AC B4GEM3.1
#=GS B2ZIC3_DROSE/1-251      AC B2ZIC3.1
#=GS Q296U9_DROPS/1-280      AC Q296U9.4
#=GS B4K6G3_DROMO/1-284      AC B4K6G3.2
#=GS B3M0P9_DROAN/1-260      AC B3M0P9.1
#=GS A0A0L0CR98_LUCCU/1-280  AC A0A0L0CR98.1
#=GS FTZ_DROME/1-248         AC P02835.2
#=GS FTZ_DROME/1-248         DR PDB; 2XHS B; 1-9;
#=GS B4NAA7_DROWI/1-267      AC B4NAA7.1
#=GS B4QYX9_DROSI/1-251      AC B4QYX9.1
#=GS F5HK01_ANOGA/1-271      AC F5HK01.1
#=GS B4JGL9_DROGR/1-301      AC B4JGL9.1
#=GS B4LYV4_DROVI/1-281      AC B4LYV4.1
B4GEM3_DROPE/1-284                 .........MATTNSQSHYY-.AD..NMYNMYHHHtahSLP...PTYYDN....--SYYQSATqSTASQWQPSPAGYQGNYGAAYGVQ..ESYSDSCYYAQSSYS....pIDATV.....PQIPAVPAMP----..---A.SQPEP..............ILAASPVKTLKRKAE-........DAAAVIAAV..EERPSTLRALLTNPVKKLKYTPDYFYTTFETVKKSPatVPAQI..KASSSPAPSYEQEYVAAPTP...........SASEDVDYLDVYSPQSQKn......hKNGEYvaGTPPPLASTPATPTSI.-VE......GISTPPQSPGVKSgta.snvSHEINHRIVTAANSgvA...ADFNWSHIEESLA...................
B2ZIC3_DROSE/1-251                 .........MATTNSQSHYSY.ADnmNMYNMYHPH...SLP...PTYYDNs..gSNAYYQNSS.-----------TYQ--SYQGYYPQ..ESYSESCYYYN----.....NQEQV.....-TTQTVPPL-----..----.-QPTT..............----PPPKATKRKAEE........DAASIIAAV..EERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAP.aVTTKV..A--ASPAPSYEQEYVTVPTP...........SASEDVDYLDVYSPQSQTq.....klKNGDF..ATPP-----PTTPTSLsPVE......GISTPPQSPGEKSss...avSQEINHRIVTAPNG..A...GDFNWSHIEETLA...................
Q296U9_DROPS/1-280                 .........MATTNSQSHYY-.AD..NMYNMYHHHtahSLP...PTYYDN....--SYYQSATqSTASQWQPSPASYQSNYGAAYGVQ..ESYSDSCYYAQSSYS....pIDATV.....---PQIPAVP----..----.AMPEP..............ILAASPVKTRKRKAE-........DAAAVIAAV..EERPSTLRALLTNPVKKLKYTPDYFYTTFETVKKSPatVPAQI..KASSSPAPSYEQEYVAAPTP...........SASEDVDYLDVYSPQSQKn......hKNGEYvaGTPPPLASTPATPTSI.-VE......GISTPPQSPGVKSata.snvSHEINHRIVTAANSgvA...AEFNWSHIEESLA...................
B4K6G3_DROMO/1-284                 .........MAATNTH---YY.AD..SMYNMYHH-...ALP...PTYYDNt.ssSSSYYQ---.---SNQSWQPASYQPSSYAHYS-Q..ESYSESCYYANYHHQ.....QQQQT.....QQPQQQQPLCLPALdaVPQY.QVPTVaep........sveASSPAPAKSRKRKAEE........SAADIIAAV..EERPSTLRALLTNPVKKLKYTPDYFYTTIEHVKR--..-PSKS..SSAGELSPCYEQDY-AVPTPstqqthmspqrSTGEDVDYLDVYSPRKPA........KHGDF..VTPPPAATTPVDGLGL.GLG.....iGISTPPQSPAEKS.......-NEINHRIVTAANA..S...NEFNWSHIEETIA...................
B3M0P9_DROAN/1-260                 .......ma-----ANSHYNYsAEnmNMYNMYHHH...SLP...PTYYDNa..sGNGYYQASS.-----------SYQ--SYQGYYPQ..ENYSENCYYYG----.....QQEQV.....PQVPEVPQVT----..----.QQPAT..............----PPPKAAKRKAEE........DAASIIAAV..EERPSTLRALLTNPVKKLKYTPDYFYTTLEQVKKTP.aPTTKA..TAAASPAPSYDQEYVTAPTP...........STSEDVDYLDVYSPQSAQsqs..lklKNGDF..ATPP-----PTTPTSLpPVE......GLSTPPQSPGEKSssassavSQEINHRIVTGPSN..A...NDFNWSHIEETLA...................
A0A0L0CR98_LUCCU/1-280             .........MAATNFYTDFS-.SN..STQNMYNY-...SNA...STYYDN....TASYYHQQQ.---SNSTWNPATYNPNFMPQYNNVglENSSSQMYNDYYNYN.....N-IN-.....----EQVSI-----..----.NTPEA..............-----PKTSLKRRASEleeeivskPAAEI-SKVetEEPPSKLRALLTNPVKKLKYSPDYYYTTFEKVNSNN.nVKTQTeqTSVPNTPPCFEQDFLSAHTPatqq...silsPNRSDVDYLDVYSPQSLKvtsnskvyKNGSS..T----TTSEPATPASL.-VD......GISTPPLSPNDKHinqnsaqQHEINHQILT----..T...NDYNWSNCEDS--pa.................
FTZ_DROME/1-248                    .........MATTNSQSHYSY.ADnmNMYNMYHPH...SLP...PTYYDNs..gSNAYYQNTS.-----------NYQ-----GYYPQ..ESYSESCYYYN----.....NQEQV.....-TTQTVPPV-----..----.-QPTT..............----PPPKATKRKAED........DAASIIAAV..EERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAP.aVSTKV..T--ASPAPSYDQEYVTVPTP...........SASEDVDYLDVYSPQSQTq.....klKNGDF..ATPP-----PTTPTSLpPLE......GISTPPQSPGEKSss...avSQEINHRIVTAPNG..A...GDFNWSHIEETLA...................
#=GR FTZ_DROME/1-248         SS    .........XXXXXXXXXXXX.XXXXXXXXXXXXX...XXX...XXXXXXX..XXXXXXXXXX.-----------XXX-----XXXXX..XXXXXXXXXXX----.....XXXXX.....-XXXXXXXX-----..----.-XXXX..............----XXXXXXXXXXXX........XXXXXXXXX..XXXX-HHHHHHT-XXXXXXXXXXXXXXXXXXXXXXX.XXXXXX..X--XXXXXXXXXXXXXXXXX...........XXXXXXXXXXXXXXXXXXX.....XXXXXXX..XXXX-----XXXXXXXXXXX......XXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXX..X...XXXXXXXXXXXXX...................
B4NAA7_DROWI/1-267                 .......ma----ASHSHYYTaAD..SMYNMYHHHhhlAAPtstSTYYDN....----YQNYQsNTGSASSWQSASYQQSYSNSYTNQ..EQFTDNCYYSG--YS....pEQMPV.....YQQQEVPSVPEATP..LESL.ALPPP..............----SPPKSLKRKAEEti...tkdTAAAVIAAV..EERPSTLRALLTNPVKKLKYTPDYFYTTFESVKKAA..VSTKI..T--SSPAPSYEPDYVAAPTP...........TASEDVDYLDVYSPKTS-........KNG--..-TPPP-STTPATPTSL.-VE......GISTPPQSPKEKN.......QEQINHRIVT----..A...NDFDWSHIEES--qi.................
B4QYX9_DROSI/1-251                 .........MATTNSQSHYSY.ADnmNMYNMYHPH...SLP...PTYYDNs..gSNAYYQNSS.-----------TYQ--SYQGYYPQ..ESYSESCYYYN----.....NQEQM.....-TTHTVPPV-----..----.-QPTT..............----PPPKATKRKAEE........DAASIIAAV..EERPSTLRALLTNPVKKLKYTPDYFYTTVEQVKKAP.aVTTKV..A--ASPAPSYEQEYVTVPTP...........SASEDVDYLDVYSPQSQTq.....klKNGDF..ATPP-----PTTPTSLpPVE......GISTPPQSPGEKSss...avSQEINHRIVTAPNG..A...GDFNWSHIEETLA...................
F5HK01_ANOGA/1-271                 msipqsqll------------.--..---------...---...----QN....-SQYAQQSQqEIQNISSISSSAYGYSATAQYNHD..EQFSSNSLHTR-HHQlenygNQFDSyygypYQTTAHYSLCGAQE.hLEEYfYKPTEversnvekrsceksCETIKPP-AMKRKISE........KETN---DN..EKDSPALRALLTNPAKKLKYNPHYAHSMTNESSRRI..EATIG..YNNGFLSPAASDRIVPDIVPls.......pnKTDDSIDSLLDNSSKQDI........VTMQC..VDYTLNSLRQITATPK.-YD......GVSTPPLSPKNME.......--------------..-...-------------saissqgvenhpkesskrt
B4JGL9_DROGR/1-301                 .........MAATNTHSHSYY.AD..SMYNMYHH-...GLP...PTYYDN....SNSYYQQSN.STSSCSSW-PTSYQPSSYAQYG-Q..ESYGESCYYSNYQHQ.....HQLQQ.....QQQQQTMTMPAPAA..LPHY.QAPAPvsvpvp..apaaatVTTPAPLKSRKRKAEE........SAADIIAAV..EERPSTLRALLTNPVKKLKYTPDYFYTTFEQVKK--..-PNRS..SSAGELSPCYEQDY-AVPTPstqqthmspqrSSSEDVDYLDVYSPRKQA........KHGDF..VTPPPAATTPTATTPAsLVDgigigiGISTPPQSPAEK-.......-NEINHRNVTAASS..SssnNEFNWSHIEETLA...................
B4LYV4_DROVI/1-281                 .........MAATNTHSHSYY.AD..SMYNMYHH-...ALP...PTYYDNtssgSSSYYQ-SN.SMASTASWQPANYQAGSYVQYG-P..ESYSESCYYANYQQ-.....TTLPQ.....PEPAAVPQYH-PTA..V---.AEPFT.............kANSPAPVKSRKRKAEE........SAAEIIAAV..EERPSTLRALLTNPVKKLKYTPDYFYTTIEPVKK--..-PSKS..SSAGELSPCYEQDY-AVPTPstqqthmspqrSTSEDVDYLDVYSPHKQA........KHGDF..ITPPPAATTPATPASL.-VDg....iGISTPPQSPAEKS.......-HEINHRIVTAATG..N...NEFNWSHIEETLA...................
#=GC SS_cons                       .........XXXXXXXXXXXX.XXXXXXXXXXXXX...XXX...XXXXXXX..XXXXXXXXXX.-----------XXX-----XXXXX..XXXXXXXXXXX----.....XXXXX.....-XXXXXXXX-----..----.-XXXX..............----XXXXXXXXXXXX........XXXXXXXXX..XXXX-HHHHHHT-XXXXXXXXXXXXXXXXXXXXXXX.XXXXXX..X--XXXXXXXXXXXXXXXXX...........XXXXXXXXXXXXXXXXXXX.....XXXXXXX..XXXX-----XXXXXXXXXXX......XXXXXXXXXXXXXXX...XXXXXXXXXXXXXXXX..X...XXXXXXXXXXXXX...................
#=GC seq_cons                      .........MAsTNopSHa.h.AD..sMYNMYHa....uLP...PTYYDN....ssuYYQpus....s..p..ssoYQ.s.hstYssQ..ESYS-SCYYss.........pQ.ps......p.tplPsl............tpPss..................sPsKutKRKAEE........sAAsIIAAV..EERPSTLRALLTNPVKKLKYTPDYFYTThEpVKKss..sso+s..sssussuPuYEQ-YVssPTP...........SsSEDVDYLDVYSPpopt........KNG-a..sTPP..s.pPsTPTSL..V-......GISTPPQSPuEKS.......ppEINHRIVTAssu..u...s-FNWSHIEEoLA...................
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