GenomeNet

Database: Pfam
Entry: FctA
LinkDB: FctA
Original site: FctA 
#=GF ID   FctA
#=GF AC   PF12892.4
#=GF DE   T surface-antigen of pili
#=GF AU   Coggill P
#=GF SE   pdb_3gld
#=GF GA   23.00 12.50;
#=GF TC   23.00 12.50;
#=GF NC   22.80 12.40;
#=GF BM   hmmbuild --amino HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Repeat
#=GF RN   [1]
#=GF RM   17012387
#=GF RT   Role of streptococcal T antigens in superficial skin infection.
#=GF RA   Lizano S, Luo F, Bessen DE;
#=GF RL   J Bacteriol. 2007;189:1426-1434.
#=GF RN   [2]
#=GF RM   17501921
#=GF RT   Streptococcus pyogenes pili promote pharyngeal cell adhesion and
#=GF RT   biofilm formation.
#=GF RA   Manetti AG, Zingaretti C, Falugi F, Capo S, Bombaci M, Bagnoli
#=GF RA   F, Gambellini G, Bensi G, Mora M, Edwards AM, Musser JM, Graviss
#=GF RA   EA, Telford JL, Grandi G, Margarit I;
#=GF RL   Mol Microbiol. 2007;64:968-983.
#=GF DR   INTERPRO; IPR022464;
#=GF CC   The FCT and equivalent region genes of Streptococcus pyogenes
#=GF CC   and other related bacteria encode surface proteins that include
#=GF CC   fibronectin- and collagen-binding proteins and the serological
#=GF CC   markers known as T antigens. Some of these proteins give rise to
#=GF CC   pilus-like appendages [1]. The FctA family is found in many
#=GF CC   Firmicutes and related bacteria. In S. pyogenes, the pili have a
#=GF CC   role in bacterial adherence and colonisation of human tissues
#=GF CC   [2].
#=GF SQ   325
#=GS R7AMG5_9ACTN/1861-1944      AC R7AMG5.1
#=GS E8JYZ6_9STRE/791-912        AC E8JYZ6.1
#=GS I5ASN7_EUBCE/2180-2265      AC I5ASN7.1
#=GS E7GLH9_CLOSY/561-646        AC E7GLH9.1
#=GS R6EZH7_9FIRM/332-406        AC R6EZH7.1
#=GS I5ASN7_EUBCE/4006-4082      AC I5ASN7.1
#=GS I5ASN7_EUBCE/2448-2531      AC I5ASN7.1
#=GS D4K284_9FIRM/96-165         AC D4K284.1
#=GS B0S4I4_FINM2/1627-1716      AC B0S4I4.1
#=GS R6RPV2_9FIRM/629-720        AC R6RPV2.1
#=GS T1ZBA4_STRIT/1606-1690      AC T1ZBA4.1
#=GS R5FRI8_9ACTN/1957-2066      AC R5FRI8.1
#=GS I1EWZ7_AMPQE/1873-1957      AC I1EWZ7.1
#=GS E8JYZ6_9STRE/1131-1222      AC E8JYZ6.1
#=GS T1ZBA4_STRIT/1832-1898      AC T1ZBA4.1
#=GS I1ER59_AMPQE/3187-3262      AC I1ER59.1
#=GS C7N0K7_SLAHD/1761-1845      AC C7N0K7.1
#=GS G9WQN7_9FIRM/1895-1978      AC G9WQN7.1
#=GS I5ASN7_EUBCE/3093-3177      AC I5ASN7.1
#=GS Q8G4A0_BIFLO/1784-1874      AC Q8G4A0.1
#=GS K4IZC5_BIFAP/1432-1493      AC K4IZC5.1
#=GS I5ASN7_EUBCE/3221-3304      AC I5ASN7.1
#=GS D1BU24_XYLCX/1220-1334      AC D1BU24.1
#=GS G9WQN8_9FIRM/1575-1666      AC G9WQN8.1
#=GS I5ASN7_EUBCE/1251-1335      AC I5ASN7.1
#=GS D1BU24_XYLCX/1523-1619      AC D1BU24.1
#=GS R7DBD0_9ACTN/1431-1520      AC R7DBD0.1
#=GS D5BH47_ZUNPS/127-221        AC D5BH47.1
#=GS C9ACY2_ENTCA/1743-1825      AC C9ACY2.1
#=GS F7V226_CLOSS/120-185        AC F7V226.1
#=GS R5F6E9_9CLOT/847-916        AC R5F6E9.1
#=GS A0A0A7I667_9BIFI/361-444    AC A0A0A7I667.1
#=GS I5ASN7_EUBCE/3351-3440      AC I5ASN7.1
#=GS R7AMG5_9ACTN/1700-1806      AC R7AMG5.1
#=GS R6EQJ6_9FIRM/544-632        AC R6EQJ6.1
#=GS R6LQH8_9FIRM/1352-1427      AC R6LQH8.1
#=GS F2N6Z0_CORGP/893-983        AC F2N6Z0.1
#=GS R5FRI8_9ACTN/1254-1354      AC R5FRI8.1
#=GS R5QC30_9FIRM/1465-1574      AC R5QC30.1
#=GS C9ACY2_ENTCA/1854-1924      AC C9ACY2.1
#=GS R7AMG5_9ACTN/1539-1648      AC R7AMG5.1
#=GS S0L7E9_ENTAV/1268-1357      AC S0L7E9.1
#=GS R6UBR2_9FIRM/843-923        AC R6UBR2.1
#=GS E1QXR0_OLSUV/609-708        AC E1QXR0.1
#=GS A8AWM6_STRGC/395-496        AC A8AWM6.1
#=GS R5FRI8_9ACTN/2553-2626      AC R5FRI8.1
#=GS F2N6Z0_CORGP/181-268        AC F2N6Z0.1
#=GS R7D5P8_9ACTN/552-632        AC R7D5P8.1
#=GS I1E5R0_AMPQE/50-125         AC I1E5R0.1
#=GS R7I535_9CLOT/545-602        AC R7I535.1
#=GS D2Q7R0_BIFDB/305-413        AC D2Q7R0.1
#=GS T1ZBA4_STRIT/1493-1577      AC T1ZBA4.1
#=GS T0TYM8_9STRE/196-268        AC T0TYM8.1
#=GS R5FRI8_9ACTN/2122-2219      AC R5FRI8.1
#=GS I3WJM1_BIFBI/391-458        AC I3WJM1.1
#=GS I1E922_AMPQE/109-186        AC I1E922.1
#=GS R6LQH8_9FIRM/801-900        AC R6LQH8.1
#=GS A8AUG9_STRGC/704-789        AC A8AUG9.1
#=GS Q8G4A0_BIFLO/1656-1743      AC Q8G4A0.1
#=GS E8JYZ6_9STRE/668-760        AC E8JYZ6.1
#=GS D4LAX1_RUMC1/500-595        AC D4LAX1.1
#=GS T1ZHC4_STRIT/631-709        AC T1ZHC4.1
#=GS R7AMG5_9ACTN/790-879        AC R7AMG5.1
#=GS T1ZBA4_STRIT/458-530        AC T1ZBA4.1
#=GS D9R7C5_CLOSW/1094-1176      AC D9R7C5.1
#=GS T1ZBA4_STRIT/1154-1238      AC T1ZBA4.1
#=GS I1ER59_AMPQE/2316-2390      AC I1ER59.1
#=GS Q8G4A0_BIFLO/2430-2483      AC Q8G4A0.1
#=GS T0U1Q7_9STRE/514-604        AC T0U1Q7.1
#=GS C7N0K7_SLAHD/1873-1955      AC C7N0K7.1
#=GS R5QC30_9FIRM/3880-3968      AC R5QC30.1
#=GS A4VW48_STRSY/244-325        AC A4VW48.1
#=GS R5QC30_9FIRM/3177-3266      AC R5QC30.1
#=GS A8AUG9_STRGC/817-911        AC A8AUG9.1
#=GS R6G4R6_9FIRM/131-223        AC R6G4R6.1
#=GS I5ASN7_EUBCE/2969-3053      AC I5ASN7.1
#=GS E6UG27_RUMA7/1339-1437      AC E6UG27.1
#=GS D2Q7R0_BIFDB/143-246        AC D2Q7R0.1
#=GS F9VBI8_LACGL/767-855        AC F9VBI8.1
#=GS B8DVQ0_BIFA0/959-1053       AC B8DVQ0.1
#=GS C7N0K7_SLAHD/2089-2171      AC C7N0K7.1
#=GS I1ER59_AMPQE/643-749        AC I1ER59.1
#=GS R5BZC7_9FIRM/1266-1345      AC R5BZC7.1
#=GS R5QC30_9FIRM/3760-3851      AC R5QC30.1
#=GS S6CLL7_9ACTN/822-926        AC S6CLL7.1
#=GS F2N6Z0_CORGP/775-865        AC F2N6Z0.1
#=GS T1ZBA4_STRIT/560-654        AC T1ZBA4.1
#=GS R6LQH8_9FIRM/1107-1198      AC R6LQH8.1
#=GS A0A0A8B3Y8_9ACTN/498-578    AC A0A0A8B3Y8.1
#=GS F4LW46_TEPAE/875-923        AC F4LW46.1
#=GS T1ZBA4_STRIT/685-774        AC T1ZBA4.1
#=GS C7N0K8_SLAHD/65-142         AC C7N0K8.1
#=GS R7BYR4_9FIRM/141-228        AC R7BYR4.1
#=GS I1ER59_AMPQE/2423-2503      AC I1ER59.1
#=GS R5H9I8_9FIRM/1094-1181      AC R5H9I8.1
#=GS A8AYR7_STRGC/479-563        AC A8AYR7.1
#=GS E6UG27_RUMA7/1193-1301      AC E6UG27.1
#=GS C7N0K7_SLAHD/1394-1473      AC C7N0K7.1
#=GS F4LW46_TEPAE/641-725        AC F4LW46.1
#=GS R6EZH7_9FIRM/160-252        AC R6EZH7.1
#=GS D1BU23_XYLCX/1406-1493      AC D1BU23.1
#=GS PILIN_STRP1/111-199         AC Q9A1S2.1
#=GS PILIN_STRP1/111-199         DR PDB; 3GLE C; 111-199;
#=GS PILIN_STRP1/111-199         DR PDB; 3B2M B; 111-199;
#=GS PILIN_STRP1/111-199         DR PDB; 3GLD C; 111-199;
#=GS PILIN_STRP1/111-199         DR PDB; 3GLD B; 111-199;
#=GS PILIN_STRP1/111-199         DR PDB; 3B2M C; 111-199;
#=GS PILIN_STRP1/111-199         DR PDB; 3GLD A; 111-199;
#=GS PILIN_STRP1/111-199         DR PDB; 3B2M A; 111-199;
#=GS PILIN_STRP1/111-199         DR PDB; 3GLE B; 111-199;
#=GS PILIN_STRP1/111-199         DR PDB; 3GLE A; 111-199;
#=GS Q8G4A0_BIFLO/2176-2259      AC Q8G4A0.1
#=GS R5DCU5_9FIRM/875-963        AC R5DCU5.1
#=GS R5R630_9FIRM/97-177         AC R5R630.1
#=GS R5FRI8_9ACTN/815-895        AC R5FRI8.1
#=GS R6EQJ6_9FIRM/661-726        AC R6EQJ6.1
#=GS R6EQJ6_9FIRM/1-82           AC R6EQJ6.1
#=GS R6S0S6_9FIRM/129-210        AC R6S0S6.1
#=GS R7A9X7_9CLOT/440-520        AC R7A9X7.1
#=GS F2N6Z0_CORGP/1249-1338      AC F2N6Z0.1
#=GS A0A0A7I667_9BIFI/114-200    AC A0A0A7I667.1
#=GS K1LMV1_9LACT/752-840        AC K1LMV1.1
#=GS B8DVQ0_BIFA0/1922-2020      AC B8DVQ0.1
#=GS R7BNW6_9ACTN/880-985        AC R7BNW6.1
#=GS R5DCU5_9FIRM/618-707        AC R5DCU5.1
#=GS R7DBD0_9ACTN/1065-1155      AC R7DBD0.1
#=GS R5H9I8_9FIRM/786-885        AC R5H9I8.1
#=GS I5ASN7_EUBCE/2320-2404      AC I5ASN7.1
#=GS R5QC30_9FIRM/3997-4082      AC R5QC30.1
#=GS I5ASN7_EUBCE/1641-1731      AC I5ASN7.1
#=GS R5RHG5_9FIRM/116-201        AC R5RHG5.1
#=GS R6I6K6_9ACTN/121-211        AC R6I6K6.1
#=GS C7N0K7_SLAHD/1513-1592      AC C7N0K7.1
#=GS R7AMG5_9ACTN/1222-1325      AC R7AMG5.1
#=GS I5ASN7_EUBCE/1382-1472      AC I5ASN7.1
#=GS R7AMG5_9ACTN/2161-2256      AC R7AMG5.1
#=GS K1LMV1_9LACT/868-952        AC K1LMV1.1
#=GS A8AUG9_STRGC/484-566        AC A8AUG9.1
#=GS R5FRI8_9ACTN/1531-1626      AC R5FRI8.1
#=GS R7AMG5_9ACTN/2560-2629      AC R7AMG5.1
#=GS R7AMG5_9ACTN/1383-1494      AC R7AMG5.1
#=GS I5ASN7_EUBCE/2834-2918      AC I5ASN7.1
#=GS A0A0A7I667_9BIFI/496-594    AC A0A0A7I667.1
#=GS D4BMF6_BIFBR/985-1070       AC D4BMF6.1
#=GS R5UAY3_9FIRM/126-214        AC R5UAY3.1
#=GS R6A378_9ACTN/231-318        AC R6A378.1
#=GS Q835V3_ENTFA/505-604        AC Q835V3.1
#=GS A8AUG9_STRGC/594-676        AC A8AUG9.1
#=GS D9R7C5_CLOSW/1341-1404      AC D9R7C5.1
#=GS T1ZBA4_STRIT/918-1002       AC T1ZBA4.1
#=GS R5QC30_9FIRM/2197-2303      AC R5QC30.1
#=GS G9WQN7_9FIRM/2018-2084      AC G9WQN7.1
#=GS R2S6L2_9ENTE/668-733        AC R2S6L2.1
#=GS B0S4I4_FINM2/2652-2732      AC B0S4I4.1
#=GS T0U1Q7_9STRE/887-979        AC T0U1Q7.1
#=GS R5FRI8_9ACTN/1672-1765      AC R5FRI8.1
#=GS E8JYZ8_9STRE/653-737        AC E8JYZ8.1
#=GS G9WQN8_9FIRM/1707-1790      AC G9WQN8.1
#=GS B8DVQ0_BIFA0/1663-1749      AC B8DVQ0.1
#=GS C9ACY2_ENTCA/1299-1381      AC C9ACY2.1
#=GS D4M147_9FIRM/122-213        AC D4M147.1
#=GS E8JYZ6_9STRE/1458-1547      AC E8JYZ6.1
#=GS B8DVQ0_BIFA0/1245-1335      AC B8DVQ0.1
#=GS K4IZC5_BIFAP/1312-1403      AC K4IZC5.1
#=GS E8JYZ6_9STRE/2437-2495      AC E8JYZ6.1
#=GS D4LL50_9FIRM/92-162         AC D4LL50.1
#=GS I1ER59_AMPQE/1881-1954      AC I1ER59.1
#=GS A0A0A7I667_9BIFI/238-324    AC A0A0A7I667.1
#=GS I5ASN7_EUBCE/2571-2655      AC I5ASN7.1
#=GS A0A0A7I667_9BIFI/807-903    AC A0A0A7I667.1
#=GS D1BU24_XYLCX/1389-1477      AC D1BU24.1
#=GS R7DBD0_9ACTN/905-1012       AC R7DBD0.1
#=GS R5FRI8_9ACTN/1811-1904      AC R5FRI8.1
#=GS B8DVQ0_BIFA0/2462-2532      AC B8DVQ0.1
#=GS R6G1F7_9FIRM/9-82           AC R6G1F7.1
#=GS D4LUK8_9FIRM/100-174        AC D4LUK8.1
#=GS C8W898_ATOPD/641-719        AC C8W898.1
#=GS I1EWZ6_AMPQE/183-241        AC I1EWZ6.1
#=GS R6SBP2_9FIRM/109-196        AC R6SBP2.1
#=GS C9ACY2_ENTCA/1410-1492      AC C9ACY2.1
#=GS C8W898_ATOPD/544-612        AC C8W898.1
#=GS B8DVQ0_BIFA0/2209-2304      AC B8DVQ0.1
#=GS R5QC30_9FIRM/2865-2955      AC R5QC30.1
#=GS R5F6E9_9CLOT/735-817        AC R5F6E9.1
#=GS F2N6Z0_CORGP/416-508        AC F2N6Z0.1
#=GS R7AMG5_9ACTN/2441-2531      AC R7AMG5.1
#=GS R7AMG5_9ACTN/1088-1183      AC R7AMG5.1
#=GS C7N0K7_SLAHD/1025-1108      AC C7N0K7.1
#=GS R5FRI8_9ACTN/2434-2524      AC R5FRI8.1
#=GS R6EZH7_9FIRM/294-350        AC R6EZH7.1
#=GS B8DVQ0_BIFA0/1786-1869      AC B8DVQ0.1
#=GS I5ASN7_EUBCE/3608-3690      AC I5ASN7.1
#=GS R5QC30_9FIRM/1913-2001      AC R5QC30.1
#=GS D2Q7R0_BIFDB/504-603        AC D2Q7R0.1
#=GS T0U385_9ENTE/856-935        AC T0U385.1
#=GS R5DCU5_9FIRM/756-846        AC R5DCU5.1
#=GS I5ASN7_EUBCE/1512-1595      AC I5ASN7.1
#=GS R5QC30_9FIRM/1762-1869      AC R5QC30.1
#=GS B0S4I4_FINM2/1510-1594      AC B0S4I4.1
#=GS R7AMG5_9ACTN/1999-2108      AC R7AMG5.1
#=GS R5EQN5_9FIRM/1014-1060      AC R5EQN5.1
#=GS R6R5R7_9FIRM/105-173        AC R6R5R7.1
#=GS F2N6Z0_CORGP/1366-1433      AC F2N6Z0.1
#=GS R6EQJ6_9FIRM/130-235        AC R6EQJ6.1
#=GS B8DVQ0_BIFA0/1384-1481      AC B8DVQ0.1
#=GS R5E850_9CLOT/32-116         AC R5E850.1
#=GS T0U1Q7_9STRE/633-727        AC T0U1Q7.1
#=GS A8AUG9_STRGC/939-1010       AC A8AUG9.1
#=GS R5QC30_9FIRM/1319-1412      AC R5QC30.1
#=GS G9WQN7_9FIRM/1765-1854      AC G9WQN7.1
#=GS I1ER59_AMPQE/2638-2712      AC I1ER59.1
#=GS I1ER59_AMPQE/2530-2609      AC I1ER59.1
#=GS R6A378_9ACTN/114-204        AC R6A378.1
#=GS D4K286_9FIRM/119-207        AC D4K286.1
#=GS R6RPV2_9FIRM/504-572        AC R6RPV2.1
#=GS A4VW48_STRSY/132-215        AC A4VW48.1
#=GS D1BU24_XYLCX/1058-1153      AC D1BU24.1
#=GS R5QC30_9FIRM/1171-1267      AC R5QC30.1
#=GS R7DBD0_9ACTN/1313-1403      AC R7DBD0.1
#=GS E8JYZ8_9STRE/772-856        AC E8JYZ8.1
#=GS R6EZH7_9FIRM/6-107          AC R6EZH7.1
#=GS D2Q781_BIFDB/1159-1227      AC D2Q781.1
#=GS E8JYZ8_9STRE/536-618        AC E8JYZ8.1
#=GS R5BZC7_9FIRM/1403-1478      AC R5BZC7.1
#=GS R2S6L2_9ENTE/762-839        AC R2S6L2.1
#=GS C7N0K7_SLAHD/1146-1227      AC C7N0K7.1
#=GS A0A0A7I667_9BIFI/933-1022   AC A0A0A7I667.1
#=GS F2N6Z0_CORGP/536-626        AC F2N6Z0.1
#=GS C7N0K7_SLAHD/1637-1718      AC C7N0K7.1
#=GS R5FRI8_9ACTN/942-995        AC R5FRI8.1
#=GS R5QC30_9FIRM/2348-2422      AC R5QC30.1
#=GS R6LQH8_9FIRM/1226-1323      AC R6LQH8.1
#=GS Q5M5C4_STRT2/105-155        AC Q5M5C4.1
#=GS B8DVQ0_BIFA0/1528-1621      AC B8DVQ0.1
#=GS F2N6Z0_CORGP/1011-1103      AC F2N6Z0.1
#=GS T1ZBA4_STRIT/1267-1349      AC T1ZBA4.1
#=GS R5H9I8_9FIRM/936-1035       AC R5H9I8.1
#=GS E6UG27_RUMA7/1599-1690      AC E6UG27.1
#=GS R6EQJ6_9FIRM/429-516        AC R6EQJ6.1
#=GS R5QC30_9FIRM/3493-3583      AC R5QC30.1
#=GS D4BMF6_BIFBR/1129-1201      AC D4BMF6.1
#=GS A0A0A7I667_9BIFI/1060-1126  AC A0A0A7I667.1
#=GS R5FRI8_9ACTN/1109-1217      AC R5FRI8.1
#=GS R5DCU5_9FIRM/350-448        AC R5DCU5.1
#=GS C9ACY2_ENTCA/1521-1603      AC C9ACY2.1
#=GS E8JYZ6_9STRE/1785-1874      AC E8JYZ6.1
#=GS A8AUG9_STRGC/374-455        AC A8AUG9.1
#=GS R3WUJ0_9ENTE/97-186         AC R3WUJ0.1
#=GS C7N0K7_SLAHD/1266-1349      AC C7N0K7.1
#=GS I5ASN7_EUBCE/1776-1870      AC I5ASN7.1
#=GS I5ASN7_EUBCE/3484-3568      AC I5ASN7.1
#=GS S0L7E9_ENTAV/1502-1588      AC S0L7E9.1
#=GS G9WQN8_9FIRM/1875-1940      AC G9WQN8.1
#=GS A0A0A7I667_9BIFI/1-76       AC A0A0A7I667.1
#=GS E8JYZ6_9STRE/2112-2203      AC E8JYZ6.1
#=GS E6UG27_RUMA7/1722-1792      AC E6UG27.1
#=GS T1ZBA4_STRIT/1031-1124      AC T1ZBA4.1
#=GS S0L7E9_ENTAV/1615-1704      AC S0L7E9.1
#=GS Q8G4A0_BIFLO/2304-2394      AC Q8G4A0.1
#=GS R6A378_9ACTN/2-86           AC R6A378.1
#=GS Q8G4A0_BIFLO/1905-1996      AC Q8G4A0.1
#=GS R5AIP6_9FIRM/462-545        AC R5AIP6.1
#=GS T1ZBA4_STRIT/1380-1464      AC T1ZBA4.1
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