GenomeNet

Database: Pfam
Entry: Fez1
LinkDB: Fez1
Original site: Fez1 
#=GF ID   Fez1
#=GF AC   PF06818.13
#=GF DE   Fez1
#=GF AU   Vella Briffa B
#=GF SE   Pfam-B_4593 (release 10.0)
#=GF GA   34.00 34.00;
#=GF TC   34.20 34.00;
#=GF NC   33.80 33.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10097140
#=GF RT   The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper
#=GF RT   protein, and its expression is altered in multiple human tumors. 
#=GF RA   Ishii H, Baffa R, Numata SI, Murakumo Y, Rattan S, Inoue H, Mori
#=GF RA   M, Fidanza V, Alder H, Croce CM; 
#=GF RL   Proc Natl Acad Sci U S A 1999;96:3928-3933.
#=GF RN   [2]
#=GF RM   11504921
#=GF RT   FEZ1/LZTS1 gene at 8p22 suppresses cancer cell growth and
#=GF RT   regulates mitosis. 
#=GF RA   Ishii H, Vecchione A, Murakumo Y, Baldassarre G, Numata S,
#=GF RA   Trapasso F, Alder H, Baffa R, Croce CM; 
#=GF RL   Proc Natl Acad Sci U S A 2001;98:10374-10379.
#=GF CC   This family represents the eukaryotic Fez1 protein. Fez1
#=GF CC   contains a leucine-zipper region with similarity to the
#=GF CC   DNA-binding domain of the cAMP-responsive
#=GF CC   activating-transcription factor 5 [1]. There is evidence that
#=GF CC   Fez1 inhibits cancer cell growth through regulation of mitosis,
#=GF CC   and that its alterations result in abnormal cell growth [2].
#=GF CC   Note that some family members contain more than one copy of this
#=GF CC   region.
#=GF SQ   394
#=GS F7IML6_CALJA/415-523       AC F7IML6.1
#=GS H2U4M7_TAKRU/453-654       AC H2U4M7.1
#=GS M4ANM3_XIPMA/311-512       AC M4ANM3.1
#=GS A0A087XQ35_POEFO/398-606   AC A0A087XQ35.1
#=GS H2URQ8_TAKRU/393-586       AC H2URQ8.1
#=GS B1H2M9_XENTR/388-468       AC B1H2M9.1
#=GS I3MPE6_ICTTR/447-644       AC I3MPE6.1
#=GS U3J9I2_ANAPL/394-588       AC U3J9I2.1
#=GS L5JRP6_PTEAL/424-621       AC L5JRP6.1
#=GS M3WN34_FELCA/440-637       AC M3WN34.1
#=GS A0A0L0CGS5_LUCCU/673-845   AC A0A0L0CGS5.1
#=GS H3DAA2_TETNG/421-624       AC H3DAA2.1
#=GS G1S0P2_NOMLE/348-431       AC G1S0P2.1
#=GS F7FLS6_RAT/440-637         AC F7FLS6.1
#=GS H3BC21_LATCH/462-542       AC H3BC21.1
#=GS A0A096NAF0_PAPAN/363-440   AC A0A096NAF0.1
#=GS G3NZ56_GASAC/459-669       AC G3NZ56.1
#=GS I3K156_ORENI/424-639       AC I3K156.1
#=GS G3NTZ6_GASAC/405-610       AC G3NTZ6.1
#=GS L5LWW9_MYODS/349-432       AC L5LWW9.1
#=GS G3RHD5_GORGO/439-636       AC G3RHD5.1
#=GS C3YJ33_BRAFL/318-530       AC C3YJ33.1
#=GS F1QXP6_DANRE/368-600       AC F1QXP6.2
#=GS H2URQ9_TAKRU/346-550       AC H2URQ9.1
#=GS V8NFE7_OPHHA/366-560       AC V8NFE7.1
#=GS H2URQ7_TAKRU/373-583       AC H2URQ7.1
#=GS N4BP3_RAT/359-442          AC Q3LUD3.1
#=GS F7CGI3_MONDO/438-640       AC F7CGI3.1
#=GS L9JG17_TUPCH/421-492       AC L9JG17.1
#=GS A0A0L7LS13_9NEOP/39-257    AC A0A0L7LS13.1
#=GS L5JXC8_PTEAL/360-439       AC L5JXC8.1
#=GS M7BL01_CHEMY/424-632       AC M7BL01.1
#=GS L8Y8Q9_TUPCH/478-513       AC L8Y8Q9.1
#=GS H9JPH3_BOMMO/177-408       AC H9JPH3.1
#=GS U3K293_FICAL/406-476       AC U3K293.1
#=GS F6YCP0_HORSE/365-437       AC F6YCP0.1
#=GS E2RFA0_CANLF/379-574       AC E2RFA0.1
#=GS A0A044SJQ2_ONCVO/301-485   AC A0A044SJQ2.1
#=GS F7I251_CALJA/380-490       AC F7I251.1
#=GS B4GVG7_DROPE/504-759       AC B4GVG7.1
#=GS E1BNL7_BOVIN/437-637       AC E1BNL7.1
#=GS G1S0P2_NOMLE/409-508       AC G1S0P2.1
#=GS A0A0Q9WN28_DROVI/516-776   AC A0A0Q9WN28.1
#=GS L9JG17_TUPCH/584-745       AC L9JG17.1
#=GS LZTS2_XENTR/446-652        AC Q6DIS8.1
#=GS U3K293_FICAL/473-575       AC U3K293.1
#=GS M3X8L2_FELCA/365-451       AC M3X8L2.1
#=GS A0A096NA49_PAPAN/380-565   AC A0A096NA49.1
#=GS E7FDI0_DANRE/461-692       AC E7FDI0.1
#=GS L5JXC8_PTEAL/428-520       AC L5JXC8.1
#=GS F1S8A9_PIG/437-637         AC F1S8A9.2
#=GS F6QLM0_XENTR/392-472       AC F6QLM0.1
#=GS I3KQ33_ORENI/372-562       AC I3KQ33.1
#=GS G1T0T7_RABIT/430-523       AC G1T0T7.1
#=GS F6ZIR0_HORSE/440-637       AC F6ZIR0.1
#=GS G1NCU4_MELGA/421-469       AC G1NCU4.1
#=GS I3KDG5_ORENI/394-596       AC I3KDG5.1
#=GS H0UV36_CAVPO/525-571       AC H0UV36.1
#=GS W5K613_ASTMX/444-664       AC W5K613.1
#=GS G3H6W2_CRIGR/378-570       AC G3H6W2.1
#=GS G3TP89_LOXAF/437-640       AC G3TP89.1
#=GS W5P7Z7_SHEEP/365-448       AC W5P7Z7.1
#=GS G5AUC7_HETGA/382-576       AC G5AUC7.1
#=GS W5KVA7_ASTMX/278-478       AC W5KVA7.1
#=GS M3XNU8_MUSPF/457-528       AC M3XNU8.1
#=GS A0A0P7UEQ3_9TELE/281-355   AC A0A0P7UEQ3.1
#=GS Q16V99_AEDAE/531-882       AC Q16V99.1
#=GS H0WUX8_OTOGA/414-523       AC H0WUX8.1
#=GS E1BWC9_CHICK/424-620       AC E1BWC9.2
#=GS B1H2M9_XENTR/328-403       AC B1H2M9.1
#=GS G5B4T3_HETGA/435-635       AC G5B4T3.1
#=GS H2PPP9_PONAB/380-507       AC H2PPP9.1
#=GS W5LZ82_LEPOC/204-419       AC W5LZ82.1
#=GS G3S1D6_GORGO/392-592       AC G3S1D6.1
#=GS LZTS2_HUMAN/439-636        AC Q9BRK4.2
#=GS W5P2R6_SHEEP/443-643       AC W5P2R6.1
#=GS N4BP3_HUMAN/366-449        AC O15049.3
#=GS D6WBJ3_TRICA/385-570       AC D6WBJ3.1
#=GS J9ET08_WUCBA/174-342       AC J9ET08.1
#=GS N4BP3_RAT/411-519          AC Q3LUD3.1
#=GS G1MY75_MELGA/476-572       AC G1MY75.1
#=GS G1PCN6_MYOLU/379-574       AC G1PCN6.1
#=GS G1SKZ7_RABIT/467-667       AC G1SKZ7.1
#=GS I3M7W2_ICTTR/465-665       AC I3M7W2.1
#=GS B0W0U9_CULQU/484-826       AC B0W0U9.1
#=GS F7IRT2_CALJA/439-569       AC F7IRT2.1
#=GS A0A091CNK3_FUKDA/435-635   AC A0A091CNK3.1
#=GS E1BLB8_BOVIN/365-447       AC E1BLB8.1
#=GS I3JM63_ORENI/457-666       AC I3JM63.1
#=GS A0A091D826_FUKDA/25-167    AC A0A091D826.1
#=GS H0W9Y9_CAVPO/426-523       AC H0W9Y9.1
#=GS A0A0M3KEA8_ANISI/2-154     AC A0A0M3KEA8.1
#=GS W5LMZ1_ASTMX/337-425       AC W5LMZ1.1
#=GS X2JD14_DROME/668-815       AC X2JD14.1
#=GS M7UHR5_BOTF1/29-186        AC M7UHR5.1
#=GS A0A096MAE4_POEFO/274-468   AC A0A096MAE4.1
#=GS E2RN73_CANLF/440-595       AC E2RN73.2
#=GS H0W9Y9_CAVPO/363-445       AC H0W9Y9.1
#=GS J9JJD1_ACYPI/295-489       AC J9JJD1.1
#=GS G6CJB5_DANPL/125-356       AC G6CJB5.1
#=GS K1QEH9_CRAGI/304-526       AC K1QEH9.1
#=GS G3VKZ8_SARHA/485-563       AC G3VKZ8.1
#=GS H2URR0_TAKRU/305-500       AC H2URR0.1
#=GS F6WBA5_MACMU/363-440       AC F6WBA5.1
#=GS H2ZY04_LATCH/385-493       AC H2ZY04.1
#=GS B3MZJ3_DROAN/444-700       AC B3MZJ3.1
#=GS F6WUB3_MONDO/463-542       AC F6WUB3.2
#=GS G1NT37_MYOLU/469-669       AC G1NT37.1
#=GS H0UWY3_CAVPO/382-575       AC H0UWY3.1
#=GS G3WS79_SARHA/381-449       AC G3WS79.1
#=GS W5KDN6_ASTMX/368-588       AC W5KDN6.1
#=GS G3SMV8_LOXAF/366-439       AC G3SMV8.1
#=GS A0A0D9R8M4_CHLSB/363-440   AC A0A0D9R8M4.1
#=GS W5LPG8_ASTMX/452-688       AC W5LPG8.1
#=GS G1KFJ9_ANOCA/469-562       AC G1KFJ9.2
#=GS A0A087XP09_POEFO/468-701   AC A0A087XP09.1
#=GS G3Q327_GASAC/356-423       AC G3Q327.1
#=GS G1KUU9_ANOCA/40-106        AC G1KUU9.1
#=GS F6U331_MACMU/492-541       AC F6U331.1
#=GS F1S3E1_PIG/429-525         AC F1S3E1.1
#=GS U3K1Z6_FICAL/536-587       AC U3K1Z6.1
#=GS H0X7X1_OTOGA/439-637       AC H0X7X1.1
#=GS A0A067QII6_ZOONE/246-497   AC A0A067QII6.1
#=GS A0A0P7UAG6_9TELE/397-595   AC A0A0P7UAG6.1
#=GS F6WX94_ORNAN/412-517       AC F6WX94.2
#=GS G1PE52_MYOLU/425-521       AC G1PE52.1
#=GS LZTS3_RAT/468-668          AC Q8K1Q4.2
#=GS I3KMM7_ORENI/367-456       AC I3KMM7.1
#=GS LZTS1_HUMAN/380-565        AC Q9Y250.3
#=GS W5NCK1_LEPOC/392-597       AC W5NCK1.1
#=GS A0A0D9RLH1_CHLSB/438-638   AC A0A0D9RLH1.1
#=GS M3WIT6_FELCA/545-611       AC M3WIT6.1
#=GS M4AT98_XIPMA/458-667       AC M4AT98.1
#=GS S9XJ05_9CETA/277-360       AC S9XJ05.1
#=GS G7PDS3_MACFA/439-636       AC G7PDS3.1
#=GS F7IML6_CALJA/363-446       AC F7IML6.1
#=GS F6U331_MACMU/380-490       AC F6U331.1
#=GS H2RNI6_TAKRU/391-483       AC H2RNI6.1
#=GS M3XNU8_MUSPF/365-442       AC M3XNU8.1
#=GS I3KMM6_ORENI/429-518       AC I3KMM6.1
#=GS U3IT14_ANAPL/348-413       AC U3IT14.1
#=GS U3K1Z6_FICAL/396-461       AC U3K1Z6.1
#=GS G1RXP2_NOMLE/439-636       AC G1RXP2.1
#=GS U4UA79_DENPD/316-536       AC U4UA79.1
#=GS W4ZEC9_STRPU/693-894       AC W4ZEC9.1
#=GS F7CFQ4_HORSE/373-568       AC F7CFQ4.1
#=GS G1T6N9_RABIT/362-550       AC G1T6N9.1
#=GS F6WX94_ORNAN/529-563       AC F6WX94.2
#=GS W5P7Z7_SHEEP/417-525       AC W5P7Z7.1
#=GS G1KUU9_ANOCA/110-205       AC G1KUU9.1
#=GS H0ZY26_TAEGU/153-257       AC H0ZY26.1
#=GS F6YBE0_HORSE/392-592       AC F6YBE0.1
#=GS A0A096LWL2_POEFO/409-617   AC A0A096LWL2.1
#=GS E1BLB8_BOVIN/430-525       AC E1BLB8.1
#=GS H3AV65_LATCH/428-610       AC H3AV65.1
#=GS G5BCC3_HETGA/529-612       AC G5BCC3.1
#=GS F7EEG2_CALJA/439-636       AC F7EEG2.1
#=GS G1PE52_MYOLU/361-444       AC G1PE52.1
#=GS H2RNI6_TAKRU/332-413       AC H2RNI6.1
#=GS F6SF96_ORNAN/394-585       AC F6SF96.2
#=GS A0A0R3P5I6_DROPS/508-765   AC A0A0R3P5I6.1
#=GS S9XVS7_9CETA/437-616       AC S9XVS7.1
#=GS F7F1L9_CALJA/392-592       AC F7F1L9.1
#=GS F1R558_DANRE/126-323       AC F1R558.1
#=GS LZTS1_MOUSE/378-568        AC P60853.3
#=GS G7PCN7_MACFA/380-565       AC G7PCN7.1
#=GS G1NKL4_MELGA/424-606       AC G1NKL4.1
#=GS M3X8L2_FELCA/433-526       AC M3X8L2.1
#=GS H2RNF6_TAKRU/383-580       AC H2RNF6.1
#=GS LZTS2_MOUSE/441-638        AC Q91YU6.3
#=GS H2LFW6_ORYLA/406-603       AC H2LFW6.1
#=GS G3QCR8_GORGO/433-526       AC G3QCR8.1
#=GS G1T0T7_RABIT/363-446       AC G1T0T7.1
#=GS M3YZS2_MUSPF/441-638       AC M3YZS2.1
#=GS Q9W3A1_DROME/493-808       AC Q9W3A1.1
#=GS G1MGT8_AILME/419-616       AC G1MGT8.1
#=GS M3ZH16_XIPMA/398-606       AC M3ZH16.1
#=GS W5NCK0_LEPOC/399-604       AC W5NCK0.1
#=GS G5CAF0_HETGA/441-638       AC G5CAF0.1
#=GS G3H438_CRIGR/465-665       AC G3H438.1
#=GS W5LMZ1_ASTMX/278-350       AC W5LMZ1.1
#=GS H2RNI7_TAKRU/377-458       AC H2RNI7.1
#=GS H3DGZ1_TETNG/302-499       AC H3DGZ1.1
#=GS G3QE89_GORGO/381-566       AC G3QE89.1
#=GS M7AZF4_CHEMY/452-545       AC M7AZF4.1
#=GS A0A0H5S9F6_BRUMA/898-1100  AC A0A0H5S9F6.1
#=GS S9X1L3_9CETA/322-423       AC S9X1L3.1
#=GS H0VWN3_CAVPO/449-649       AC H0VWN3.1
#=GS F1MY71_BOVIN/437-634       AC F1MY71.1
#=GS F7GB08_ORNAN/327-392       AC F7GB08.1
#=GS A0A087YFE1_POEFO/458-667   AC A0A087YFE1.1
#=GS F6WXA4_ORNAN/184-384       AC F6WXA4.1
#=GS B8A6E8_DANRE/479-710       AC B8A6E8.1
#=GS F6YCP0_HORSE/426-525       AC F6YCP0.1
#=GS H2PHJ4_PONAB/427-526       AC H2PHJ4.1
#=GS A0A087XCF1_POEFO/376-459   AC A0A087XCF1.2
#=GS H2SEC7_TAKRU/437-646       AC H2SEC7.1
#=GS L5L721_PTEAL/274-469       AC L5L721.1
#=GS A0A087XE53_POEFO/485-719   AC A0A087XE53.2
#=GS H2SEC9_TAKRU/288-467       AC H2SEC9.1
#=GS G3P8T9_GASAC/385-574       AC G3P8T9.1
#=GS M3YBW2_MUSPF/438-638       AC M3YBW2.1
#=GS G3SMV8_LOXAF/414-526       AC G3SMV8.1
#=GS H0ZL51_TAEGU/425-606       AC H0ZL51.1
#=GS H2M473_ORYLA/397-531       AC H2M473.1
#=GS G3WL08_SARHA/446-642       AC G3WL08.1
#=GS G7P713_MACFA/363-440       AC G7P713.1
#=GS H1A3V8_TAEGU/98-286        AC H1A3V8.1
#=GS F6SYU4_MONDO/378-501       AC F6SYU4.1
#=GS F6WUB3_MONDO/380-457       AC F6WUB3.2
#=GS G3QCR8_GORGO/366-449       AC G3QCR8.1
#=GS W5Q3K7_SHEEP/363-556       AC W5Q3K7.1
#=GS G1M1W4_AILME/381-576       AC G1M1W4.1
#=GS B4IJP4_DROSE/484-754       AC B4IJP4.1
#=GS A0A0P7UEQ3_9TELE/363-432   AC A0A0P7UEQ3.1
#=GS H3A1M8_LATCH/446-647       AC H3A1M8.1
#=GS G3QZX8_GORGO/438-638       AC G3QZX8.1
#=GS LZTS1_RAT/378-570          AC Q8CFC9.3
#=GS A0A096NV95_PAPAN/438-638   AC A0A096NV95.1
#=GS H0WUX8_OTOGA/363-435       AC H0WUX8.1
#=GS A0A096NAF0_PAPAN/428-523   AC A0A096NAF0.1
#=GS F7AYC6_MACMU/439-636       AC F7AYC6.1
#=GS H2R543_PANTR/366-449       AC H2R543.1
#=GS F1QA84_DANRE/283-353       AC F1QA84.2
#=GS LZTS3_HUMAN/438-638        AC O60299.1
#=GS H2SEC6_TAKRU/447-656       AC H2SEC6.1
#=GS G7P713_MACFA/428-523       AC G7P713.1
#=GS M4A6E7_XIPMA/443-531       AC M4A6E7.1
#=GS G1MSE8_MELGA/389-575       AC G1MSE8.1
#=GS L5MD24_MYODS/462-659       AC L5MD24.1
#=GS G1R7P0_NOMLE/438-638       AC G1R7P0.1
#=GS W5PLX6_SHEEP/412-601       AC W5PLX6.1
#=GS G3WS80_SARHA/381-449       AC G3WS80.1
#=GS E2QWW8_CANLF/438-638       AC E2QWW8.2
#=GS A0A093BJC4_CHAPE/423-631   AC A0A093BJC4.1
#=GS H2PHJ4_PONAB/366-438       AC H2PHJ4.1
#=GS I3KMM7_ORENI/429-525       AC I3KMM7.1
#=GS F6X156_XENTR/417-600       AC F6X156.1
#=GS F7F1L5_CALJA/438-638       AC F7F1L5.1
#=GS U3JWL5_FICAL/386-577       AC U3JWL5.1
#=GS H9GH55_ANOCA/413-606       AC H9GH55.1
#=GS L5LWW9_MYODS/413-509       AC L5LWW9.1
#=GS A0A0H5S8T5_BRUMA/215-423   AC A0A0H5S8T5.1
#=GS F1S3E1_PIG/365-448         AC F1S3E1.1
#=GS E1FKA6_LOALO/222-430       AC E1FKA6.1
#=GS H2RNI8_TAKRU/252-446       AC H2RNI8.1
#=GS M3XYT2_MUSPF/380-575       AC M3XYT2.1
#=GS V4AVI6_LOTGI/265-432       AC V4AVI6.1
#=GS F6QLM0_XENTR/332-407       AC F6QLM0.1
#=GS I3N9U1_ICTTR/430-523       AC I3N9U1.1
#=GS A0A0N4SYD2_BRUPA/329-535   AC A0A0N4SYD2.1
#=GS F7HZV7_CALJA/380-565       AC F7HZV7.1
#=GS M3ZAS9_NOMLE/468-668       AC M3ZAS9.1
#=GS B4JWQ3_DROGR/470-730       AC B4JWQ3.1
#=GS G3T4Q1_LOXAF/445-642       AC G3T4Q1.1
#=GS A0A0D9RVU9_CHLSB/380-565   AC A0A0D9RVU9.1
#=GS H3CWZ6_TETNG/384-585       AC H3CWZ6.1
#=GS A0A0D9R8M4_CHLSB/428-523   AC A0A0D9R8M4.1
#=GS B4M396_DROVI/509-769       AC B4M396.2
#=GS V8PGU9_OPHHA/424-617       AC V8PGU9.1
#=GS T1ET82_HELRO/231-434       AC T1ET82.1
#=GS H0ZY26_TAEGU/88-158        AC H0ZY26.1
#=GS G1U8M9_RABIT/284-481       AC G1U8M9.1
#=GS L5JX45_PTEAL/441-641       AC L5JX45.1
#=GS Q7PQD2_ANOGA/539-703       AC Q7PQD2.5
#=GS F6SYU4_MONDO/491-540       AC F6SYU4.1
#=GS H2LRU8_ORYLA/320-526       AC H2LRU8.1
#=GS W5JDR4_ANODA/593-776       AC W5JDR4.1
#=GS A0A091EAM5_FUKDA/219-267   AC A0A091EAM5.1
#=GS E0VSM1_PEDHC/472-579       AC E0VSM1.1
#=GS E7F179_DANRE/440-671       AC E7F179.1
#=GS F7EEH2_CALJA/428-625       AC F7EEH2.1
#=GS E9GU34_DAPPU/392-506       AC E9GU34.1
#=GS M7AZF4_CHEMY/376-441       AC M7AZF4.1
#=GS E9GU34_DAPPU/350-418       AC E9GU34.1
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N4BP3_RAT/359-442                     ...................................................................................................................a-RWEVC...QKTAE..ISLLKQQLREAQAELAQKLAEIFSLK..TQL.R.G.SR....AQAQAQDA.E.L.ARLR....EAVR.SLQEQ.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------apreeapgscetddcks........................................
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U3K293_FICAL/406-476                  ....................................................................................................................TKWEVC...QKAAE..ISLLKQQLRDTQEEMAQKLGEIFSLK..TQL.R.E.AK....AEVQARDS.Q.L.AQLA....DSFQ.S----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------ppepstsl.................................................
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E2RFA0_CANLF/379-574                  ....................................................................................................................TQWEVC...QKSGE..ISLLKQQLKESQTEINTKASEILSLK..AQL.K.D.TR....GKLEGMEL.K.T.QDLE....SALR.TKGLE.................LE.VCE.N....ELQRK........................KNE...S...EL....L..RE.KVNLL...EQE.LLELRA..QAALQRE-...-A.VSL.....................................................................................................................................-----.----..--Gpglgp...........................................................................................................gpgpafSEDI.PAL.QRELERL...R.A......................ELK.EERQG..H.DQMSSGFQHERLVWKEEKEKV.IQYQKQL.QQSYLAMYQRNQRLEKAL-q........................................................
A0A044SJQ2_ONCVO/301-485              ..................................................................................................eqneevvvkvylekerlw------...-----..-------------------------K..EQL.A.D.LK....QKLQASQQ.G.E.NALR....QQIQ.RCNEE.................RE.QFR.V....TIQNL........................TSD...K...QG....L..QR.KCLQI...ERE.LFQLRE..CFDELIRN...RD.ETIcgpcrkr......................................................................................................................itcdiaatNTN--.----..--Nnitdkrakp...................................................................................................plptprypkeLSSE.REL.RDEVEEL...R.D......................EVS.TLRDT..L.NEQIGLFADERKRWEEERIKI.LK-----.-------------------ssn......................................................
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B4GVG7_DROPE/504-759                  ...................................................................................................................s-EWKVC...ERNGE..IALLKTQLKEAHIEINVKDHAIVSLK..HHN.H.S.NS....SSTKSSSE.T.K.SQ--....SQPK.EEQHH.................QH.QHQ.H....QLQQL........................QKI...I...AL....K..DQ.VIGAL...TNE.LAKLRK..ELSDLAIA...HE.YGEepcgrytrlkqqldnlneicqktrky................................................................................tssaeaavpapvplevvvappprldaiMQRLQ.LRDQ..GQG......................................................................................................................QGQG.QGQ.QQTLDTL...I.Eest...............tyaeDIA.KLRQK..L.DDFRINLELEKRQWCAEKDKV.LGYQKQL.QAHYIHMYQKLRCLDNAV-p........................................................
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L9JG17_TUPCH/584-745                  xxxegtlqlqlcmaqqeqrrlrkelraqqglapetrppgplpeadpsirpeeearwedaelarlrealrslqeqapreeapgscetddcksrglrgeaggrggxxxxxxxxxxxxx------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.-XXXXXXXRERRTGQEEKERV.LRYQREI.QGGYMDMYRRNQALEQEL-r........................................................
LZTS2_XENTR/446-652                   ....................................................................................................................TKWEVC...QKSGE..ISLLKQQLKDSQAELAQKSNEILLLR..AQV.R.E.AR....SDLQISEE.Q.V.QELQ....DTAH.TKTLE.................LE.VCE.N....ELQRK........................KNE...A...EL....L..RE.KASKL...DQE.VAGLRE..AAVANLRH...GL.CLCheke............................................................................................................................dpfllYESDE.AKAQ..RQN......................................................................................................................ADNL.QGL.QQYVERL...R.E......................ALT.SERRR..Y.QEQADSFEDERRIWQEEKEKV.IRYQKQL.QHNYIQMYQQNRELERDI-k........................................................
U3K293_FICAL/473-575                  .................................................................................................stslplgddpmpscqdfpg------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................CETDD.SKCR..GLQ......................................................................................................................SDSA.EPL.ERQVEWL...W.A......................ELL.RERRQ..G.QLQAVNFELERKTWQEEKEKV.LRYQREL.QASYMEMYHRSQALEREL-r........................................................
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L5JXC8_PTEAL/428-520                  ......................................................................................preeapgscetddcksrgllgeaggseagd------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.--GAKQL...R.A......................ELL.QERLR..G.QEQALRFEQERRTWQEEKERV.LRYQREI.QGGYMDMYRRNQALEQELQ.........................................................
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M3XNU8_MUSPF/457-528                  ..........................................................................................................gsegggaggg------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.---TEQL...R.A......................QLV.QERLR..A.QEQALCFERERRTWQEEKERV.LRYQREI.QGGYLDMYRRNQALEQEL-r........................................................
A0A0P7UEQ3_9TELE/281-355              ...................................................................................................................s-QWKVC...QKSGE..IALLKQQLRDSQAEVAQKLSEIFCLK..TRL.H.E.AQ....CKMRAKDD.Q.I.DMLQ....LALQ.QES--.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------hhspkevpea...............................................
Q16V99_AEDAE/531-882                  ...................................................................................................................s-EWSLC...QRNGE..VALMKSQLKDAQAEVTTKDQEILQLR..SDI.K.L.QN...yDDISLKKS.EiT.KELD....FDLE.ISQLNriii........fkdqiIV.VMN.N....EIQKLr.....................keLSD...I...SI....L..RG.YEGAP...PGR.YSRYKK..KLEYMAQK...FE.ESTgksdtnnnhkvvptevvsaekasdsnaanptkksdltsgdiirnyfnnkmelnkklflntq...........icnysdedkssiienynakqlpditldlssivsppsksktpneppptynqsssspssdddyK----.----..--Smtp................................................................................................................trdQEED.DDE.EAEVRAL...T.DkadpapskdalsscdkkpskdlQIT.QLRKE..L.DHCRSEFEQERHKWADEKEKV.LIYQRQL.QQNYVEMCKRTALLEEKL-k........................................................
H0WUX8_OTOGA/414-523                  ...................................................................................................................a------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...--E.LARLRQ..AVRSLQEQ...AP.REEap.................................................................................................................................gsCETDD.CKSR..ELL.....................................................................................................................gEAGG.SEA.RDSAEQL...R.A......................ELL.QERLR..G.QEQALRFEQERRTWQEEKERV.LRYQREI.QGGYMDMYRRNQALEQEL-r........................................................
E1BWC9_CHICK/424-620                  ....................................................................................................................TKWEVC...QKSGE..ISLLKQQLKESQAELAQRGTELLVLR..AQL.R.E.AR....AELQAGEQ.Q.A.RGLQ....EAAR.LKALE.................LE.VCA.N....ELQRR........................KSE...A...DL....F..RA.KAGRL...EQE.VAGLRD..AARGRCPQ...PS.EGC.....................................................................................................................................PE-PS.EEPR..GMA......................................................................................................................GLGM.AGL.QRQLERL...R.A......................EVA.LERRR..G.QEQRDAFEQERSTWQGEKERV.IRYQKQL.QYNYIQMYRRNRRLEQRL-q........................................................
B1H2M9_XENTR/328-403                  ....................................................................................................................TQWEAC...QKPGE..ISSLRQQLRDTQEESSLRASEILSLK..AQL.R.E.TK....GRAEAQEQ.R.A.RETE....ERLR.IMEED.................RE.ERE.Q....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------dqs......................................................
G5B4T3_HETGA/435-635                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLSEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFG.SKQAS.................LE.LAE.G....ELPATchk.................pvltPVD...P...AD....P..QE.ALATC...ESD.EAKMRR..QAGVAA--...--.AAS.....................................................................................................................................LVSMD.GEVD..AGG......................................................................................................................ESGT.RAL.RREVGRL...Q.A......................ELA.AERRA..R.ERQGASFAEERRVWLEEKEKV.IEYQKQL.QLSYVEMYQRNQQLERRL-r........................................................
H2PPP9_PONAB/380-507                  ....................................................................................................................TQWEVC...QKSGE..ISLLKQQLKESQTEVNAKASEILGLK..AQL.K.D.TR....GKLEGLEL.R.T.QDLE....GALR.TKGLE.................LE.VCE.N....ELQRK........................KNE...A...EL....L..RE.KVHLL...EQE.LQELRA..QAAL----...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------ardmgpptfpedvpalqrelerl..................................
W5LZ82_LEPOC/204-419                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLRESQAEVAQRAGEMVALR..AQL.R.E.LS....GQLREREE.A.V.LGLK....DSYS.SKSLA.................LE.RCE.G....ELQRT........................LAE...V...SL....L..RD.KLGVF...EAE.VLGLKQ..ALVELGGA...GR.AAVpspqsppdgp.................................................................................................................pppqadallsLQSDE.AKAQ..RQA......................................................................................................................--EA.GGL.RRQLERL...Q.G......................ELR.LERQQ..R.ERQALSFAKERHTWQGEKERV.LKYQAQL.QLNYVEMYQKNQALEQQV-g........................................................
G3S1D6_GORGO/392-592                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLSEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFS.SKQAS.................LE.LGE.G....ELPAAclk.................paltPVD...P...AE....P..QD.ALATC...ESD.EAKMRR..QAGVAA--...--.AAS.....................................................................................................................................LVSVD.GEAE..AGG......................................................................................................................ESGT.RAL.RREVGRL...Q.A......................ELA.AERRA..R.ERQGASFAEERRVWLEEKEKV.IEYQKQL.QLSYVEMYQRNQQLERRL-r........................................................
LZTS2_HUMAN/439-636                   ....................................................................................................................TKWEVC...QKSGE..ISLLKQQLKESQAELVQKGSELVALR..VAL.R.E.AR....ATLRVSEG.R.A.RGLQ....EAAR.ARELE.................LE.ACS.Q....ELQRH........................RQE...A...EQ....L..RE.KAGQL...DAE.AAGLRE..PPVPPATA...DP.FLL.....................................................................................................................................AESDE.AKVQ..RAA......................................................................................................................AGVG.GSL.RAQVERL...R.V......................ELQ.RERRR..G.EEQRDSFEGERLAWQAEKEQV.IRYQKQL.QHNYIQMYRRNRQLEQELQ.........................................................
W5P2R6_SHEEP/443-643                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLNEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFS.SKQAS.................LE.LGE.G....ELPSAclk.................paltPVD...P...AE....P..QD.ALATC...ESD.EAKMRR..QAGVAA--...--.AAS.....................................................................................................................................LVSLD.GEVD..AGG......................................................................................................................ESGT.RAL.RREVGRL...Q.A......................ELA.AERRA..R.ERQGASFAEERRVWLEEKEKV.IEYQKQL.QLSYVEMYQRNQQLERRL-r........................................................
N4BP3_HUMAN/366-449                   ...................................................................................................................a-RWEVC...QKTAE..ISLLKQQLREAQAELAQKLAEIFSLK..TQL.R.G.SR....AQAQAQDA.E.L.VRLR....EAVR.SLQEQ.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------apreeapgscetddcks........................................
D6WBJ3_TRICA/385-570                  ....................................................................................................................TEWGLC...QKTGE..ISLLKSQLKDYQNEQTAKCQELLQLR..TEH.R.D.FR....EQLDLREA.E.I.SELR....HQSE.EKDAE.................IK.LLK.E....QLARL........................GNK...S...PT....-..--.-IDDL...KEE.IRELRE..ELSDMSLS...EY.GSV.....................................................................................................................................EPGRS.----..---......................................................................................................................-QRI.SQE.DLEIECS...C.S......................SLA.KLKQE..I.ASKTKDFENERVVWAQEKEKV.LRYQRQL.QMNYVQMYRRTRALEAEV-e........................................................
J9ET08_WUCBA/174-342                  .................................................................................................................lwq------...-----..--------------------------..EQL.A.D.LK....QKLQASQQ.G.E.NALR....QQIQ.RCNEE.................RE.QFR.G....TIQNL........................TSD...K...QG....L..QR.KCLQI...ERE.FFQLRE..CFDELIRN...RD.ETVcgpcrkrit..................................................................................................................cyitaantnnS----.----..--Ivdkrvrpp.....................................................................................................lptpryskeSSSE.REL.RNEVDEL...R.D......................EVS.TLRDT..L.NEQIGLFADERKRWEEERIKI.LK-----.-------------------ssn......................................................
N4BP3_RAT/411-519                     ...................................................................................................................e------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.LARLRE..AVRSLQEQ...AP.REEap.................................................................................................................................gsCETDD.CKSR..GLL.....................................................................................................................gEAGG.NEA.REGAEQL...R.A......................ELL.QERLR..G.QEQALRFEQERQTWQEEKERV.LRYQREI.QGSYMDMYRRNQALEQEL-r........................................................
G1MY75_MELGA/476-572                  .......................................................................................................gddpmpacqdfpg------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................CETDD.SKCR..GLH......................................................................................................................SDSA.EPL.ERQVEWL...W.A......................ELL.RERRQ..G.QLQAVNFELERKTWQEEKEKV.LRYQREL.QASYMEMYHRSQVLEREL-r........................................................
G1PCN6_MYOLU/379-574                  ....................................................................................................................TQWEVC...QKSGE..ISLLKQQLKESQMEVNAKASEILSLK..AQL.K.D.TR....GKLEGMEL.T.T.RDLE....SALR.TKGLE.................LE.VCE.N....ELQRK........................KNE...S...EL....L..RE.KVNLL...EQE.LQDLRA..QAALQRDC...TP.R--.....................................................................................................................................GPVLG.AGPG..PTF......................................................................................................................SEDI.PAL.QRELERL...R.A......................ELK.EERQG..H.DQMSSGFQHERLVWKEEKEKV.IQYQKQL.QQSYLAMYQRNQRLEKAL-q........................................................
G1SKZ7_RABIT/467-667                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLSEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFG.SKQAS.................LE.LGD.G....ELPAAclk.................ppltPVD...P...AE....P..PE.ALATC...ESD.EAKMRR..QAGVAA--...--.AAS.....................................................................................................................................LASVD.GEAD..AGG......................................................................................................................ENGT.RAL.RREVGRL...Q.A......................ELA.AERRA..R.ERQGASFAEERRVWLEEKEKV.IEYQKQL.QLSYVEMYQRNQQLERRL-r........................................................
I3M7W2_ICTTR/465-665                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLSEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFG.SKQAS.................LE.LGE.G....ELPATclk.................paltPVD...P...AE....P..QE.ALATC...ESD.EAKMRR..QAGVAA--...--.AAS.....................................................................................................................................LVSMD.GEVD..AGG......................................................................................................................ENGT.RAL.RREVGRL...Q.A......................ELA.AERRA..R.ERQGASFAEERRVWLEEKEKV.IEYQKQL.QLSYVEMYQRNQQLERRL-r........................................................
B0W0U9_CULQU/484-826                  ...................................................................................................................s-EWSLC...QRNGE..VALMKTQLKEAQTDVISKDQEILQLK..TDL.K.L.QN...iDEISMKKS.E.IkKELD....FDLE.ISQLNriii........fkdqiIV.VMN.N....EIQKLr.....................keLSD...I...SI....M..RG.YEGVP...AGR.YSRYKK..KLDYVTQK...FE.ESTmidgnnnsktvksvsegvegdalkskkggegelssseiirnyfnnklelnkklflntqicnysdedkssfietynakklpditldlskigktattattatttptsgeevkdsslndsykesssdddyksmtptR----.----..--Eqeegded.......................................................................................................getakncdKDPP.QDK.DRTVGRL...R.Q......................ELQ.EARAG..-.------FEQERQKWAEEKEKV.LVYQRQL.QQNYVEMCKRTAALEERL-k........................................................
F7IRT2_CALJA/439-569                  ....................................................................................................................TKWEVC...QKSGE..ISLLKQQLKESQAELVQKGSELVALR..VAL.R.E.AR....ATLRVSEG.R.A.RGLQ....EAAR.ARELE.................LE.ACS.Q....ELQRH........................RQE...A...ER....L..RE.KAGQL...DAE.AAGLRE..P-------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------pmppatadpfllaesdeasatanpahrrf............................
A0A091CNK3_FUKDA/435-635              ....................................................................................................................TKWEVC...QKVGE..ISLLKQQLKDSQADVSQKLSEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFG.SKQAS.................LE.LAE.G....ELPANclk.................paltPVD...P...AE....P..QE.ALATC...ESD.EAKMRR..QAGVAAA-...--.-AS.....................................................................................................................................LVSID.GEAD..AGG......................................................................................................................ENGT.RAL.RREVGRL...Q.A......................ELA.AERRA..R.ERQGASFAEERRVWLEEKEKV.IEYQKQL.QLSYVEMYQRNQQLERRL-r........................................................
E1BLB8_BOVIN/365-447                  ...................................................................................................................a-RWEVC...QKTAE..ISLLKQQLREAQAELAQKLAEIFSLK..TQL.R.G.SR....AQAQAQDA.E.L.ARLR....EAVR.SLQEQ.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------apreeapgscetddck.........................................
I3JM63_ORENI/457-666                  ....................................................................................................................TKWEVC...QKSGE..ISLLKQQLKEVQSELAQRVGEIVSLR..GQL.R.E.TR....GELTNTQV.L.L.QEAH....GTIR.TRTLE.................LE.VCE.N....ELQRR........................KSE...A...EL....L..RE.KVGRL...EGE.MAHLRD..ALANQGPG...NR.QCQvfqea..........................................................................................................................eeqllaYESDE.AKAQ..RKS.....................................................................................................................nTEAL.QSM.KVQMDRM...R.S......................ELA.FERQK..A.EQQLGSFEEERKIWQEEKDKV.IRYQKQL.QQNYVQMYRRNRELEQLL-q........................................................
A0A091D826_FUKDA/25-167               .........................................................speelqaalagsrgarqpdgllrkglgqrellsylhlpkkdgkstkrvprneaanyttl------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................YSREH.PRAG..DFS......................................................................................................................KTSL.PER.GRFDKHL...R.A......................ELL.QERLR..G.QEQALRFEQERRTWQEEKERV.LRYQREI.QGGYMDMYRRNQALEQEL-r........................................................
H0W9Y9_CAVPO/426-523                  ......................................................................................lqeqapreeapgscetddcksrglrgepgg------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.SES.GEGAEQL...R.A......................ELL.QERLR..G.QEQALRFEQERRTWQEEKERV.LRYQREI.QGGYLDMYRRNQALEQEL-r........................................................
A0A0M3KEA8_ANISI/2-154                ................................................................................................................lsqa------...-----..--------------------------..---.-.-.--....-----SQQ.G.E.NALR....QQIQ.RCNEQ.................RE.QFQ.T....TIQNL........................NCD...K...QG....L..QR.KCVQI...ERE.MFQIRE..RFDEMLRN...RP.SSSecdhckrfss................................................................................................................nvdfdrnrskpSLPLS.ASKQ..KDS......................................................................................................................SCTN.DEL.RLEVEQL...R.G......................EIS.TLRET..L.NEQIGMFGDERRRWEMERNKM.LQ-----.-------------------lnp......................................................
W5LMZ1_ASTMX/337-425                  ...................................................................................................alqserrkggafddgqp------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................TQES.QQS.RATEERL...R.A......................ELL.LERRQ..S.EAQASAFEAERNTWQLEKEKV.IRYQREL.QASYLEMYHKNESLEREL-m........................................................
X2JD14_DROME/668-815                  ..............................................................................................................grytrl------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..KQ.QLDNL...NEI.CQKTRK..YTTTS---...--.--Asptavaspaaqvapp......................................................................................................apspaahvatpscaqeLPKLD.VLVQ..RLQ......................................................................................................................LDQG.QGT.QQTLDTL...I.Eest...............tyaeDIA.KLRQK..L.DDFRLNLELEKRQWSAEKDKV.LGYQKQL.QAHYIQMYQKLRCLD----sa.......................................................
M7UHR5_BOTF1/29-186                   ................................................................................................................atra------...----E..IAGLRVEVRGIQAELRQKEQRIIGLG..DEV.G.E.IR....GEMRGVGE.D.L.RTMR....RELW.ETREE.................IL.RLR.N....EAIQY........................RED...L...RG....L..RE.NILDM...EGE.ILRLRG..EIRNGIRG...MR.EEV.....................................................................................................................................LDFMD.-EVE..RGQ......................................................................................................................SERL.TVA.TMTTERL...R.R......................EVM.EELIR..R.DA--NNFQME-----------.-------.-------------------lrlmeg...................................................
A0A096MAE4_POEFO/274-468              ....................................................................................................................TQWEVC...QKSGE..ISLLKQQVRDSQAEVTQKLSEIFKLK..TQL.R.E.TR....TELRNREA.Q.I.DALN....IILQ.GTQRG.................--.RCS.S....AGESR........................KGA...E...ET....P..SA.GICGF...VFP.ILDPKS..GYSCVTRS...GV.QSC.....................................................................................................................................EHLPE.AGVF..RNL......................................................................................................................-PFS.SSG.GPTEERL...R.A......................ELL.LERRQ..S.EAQATAFEEERNTWQTEKDKV.IRYQKEL.QASYLEMYHRNEALERELQ.........................................................
E2RN73_CANLF/440-595                  ....................................................................................................................TKWEVC...QKSGE..ISLLKQQLKESQAELVQKGSELVALR..VAL.R.E.AR....AALRVSEG.R.A.RGLQ....EAAR.ARELE.................LE.ACS.Q....ELQRH........................RQE...A...ER....L..RE.KAGQL...DTE.AAGLRE..PHVPPATA...DP.FLL.....................................................................................................................................AESDE.AKVQ..RAA......................................................................................................................AGVG.GSL.RAQGEGG...G.R......................EAD.SERE-..-.---------------------.-------.-------------------takpaek..................................................
H0W9Y9_CAVPO/363-445                  ...................................................................................................................a-RWEVC...QKTAE..ISLLKQQLREAQAELAQKLAEIFNLK..TQL.R.G.SR....AQAQAQDV.E.L.ARLR....EAMR.SLQEQ.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------apreeapgscetddck.........................................
J9JJD1_ACYPI/295-489                  ....................................................................................................................TEWGLC...QKSGE..LAHVKSQLKDTQNELTTKGHEVIALK..SEI.R.D.LL....QKLESKER.R.I.DEIE....GRRP.ERLDSdn............ggdGN.CCD.D....QLAAD........................K-L...C...SL....V..GR.LNEQV...ENE.LSKSNK..LLSECYST...ED.LHS.....................................................................................................................................LLPKK.DTEA..DSP......................................................................................................................LERF.REL.ERHTAKL...I.R......................VLN.EERKN..-.------WDQERLKWFQEKEKV.LCYQRQL.QMNYVQMFRRTQAFEAQI-e........................................................
G6CJB5_DANPL/125-356                  ....................................................................................................................TEWSLC...QRAGE..IALLKTQLKEAQNEQTAKGHEYLTLK..SDC.R.Q.LR....EALDKKDK.E.I.LRLR....AESE.EKEKS.................MK.KLQ.A....EVERLnndlmn............svtdltKTK...E...SN....-..KK.EIEKL...KTE.VKELRQ..ELSDVSLS...GY.EGIecgr............................................................................................................................tmrgiYDVCK.TNEY..HWT......................................................................................................................SSDS.ALE.DAEVQRL...N.Gelpdscse.....pcpagaivdRLK.CEIQN..K.EQQ---FNNERRKWSDEKDKV.LRYQKQL.QMNYVQMFKRSRTLEAEI-d........................................................
K1QEH9_CRAGI/304-526                  ........................................................................................................syekendslltq------...-----..---------------------VVNVS..LQG.D.R.TA....EDMEDLQS.Q.V.EILN....QSLS.EKSVE.................IS.ELQ.S....KLQHY........................ESE...S...QRkdfqL..GE.KFREVlakTEE.LKSLRA..NLRRVSNN...NV.MDIldcsfnhsgeefsapdlgdrs...........................................................................................spltssrltsplshglprsspL----.SNKS..SSS......................................................................................................................LNSE.SDK.DKVILQL...Q.R......................ELE.ELKNG..L.VGKNEVFEKEKEQWLDEKNKV.IRYQKQL.QLNYVQMYNKNKMLEAEV-e........................................................
G3VKZ8_SARHA/485-563                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKESQADVSQKLSEIVGLR..SQL.R.E.GR....ASLRQKEE.Q.L.LTLR....DSLG.AKQPS.................LE.L--.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------qlregeaep................................................
H2URR0_TAKRU/305-500                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLRESQAEVTQRAGEMLALR..GQL.K.E.LN....AQLREREE.A.M.LGLK....DSYS.TKTLE.................LE.KCE.G....ELRRT........................LSE...V...SI....L..RE.KLGVF...EAE.VLSLNN..SLTPTS--...DT.LLS.....................................................................................................................................LQSDE.AKAQ..RQE......................................................................................................................AQRA.GEL.RRQLEQL...Q.A......................ALR.LERQH..R.ERQALNFDQERHTWQDEKERV.LKYQAQL.QLSYVETLQKNQALEKRM-s........................................................
F6WBA5_MACMU/363-440                  ...................................................................................................................a-RWEVC...QKTAE..ISLLKQQLREAQAELAQKLAEIFSLK..TQL.R.G.SR....AQAQAQDA.E.L.VRLR....QAVR.SLQEQ.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------apreeapgsce..............................................
H2ZY04_LATCH/385-493                  ...................................................................................................................a-QWEVC...QKSGE..ISLLKQQLKESQTDVNQKISEILSLR..TQL.K.E.AK....GKIEYLQQ.S.I.QQME....NSLH.TRTVE.................LE.VCE.N....ELQRK........................KSE...A...EL....L..RE.KVGRL...EQE.ILDLKA..ELMLV---...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------keq......................................................
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F6WUB3_MONDO/463-542                  .................................................................................................cetddsksqglrgevgggg------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.---AERL...W.T......................ELQ.RERQQ..G.REQALLFEQERRTWQEEKNRV.LRYQREI.QVG----------------gpemeqcacvereld..........................................
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W5P2R8_SHEEP/436-554                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLNEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFS.SKQAS.................LE.LGE.G....ELPSAclk.................paltPVD...P...AE....P..QD.ALATC...ESD.EAKMR-..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------rqagvaaarslv.............................................
A0A0Q9WCB5_DROVI/487-747              ...................................................................................................................s-EWKVC...ERNGE..IALLKTQLKEAHLEINMKDHAIVSLR..HSN.N.I.NQ....L-NNNNNN.N.N.YNNN....NNYN.NNNNNncktitcqsqpkqqteeNQ.QQE.Q....QLQQL........................NKI...I...AL....K..DQ.VIGAL...TNE.LAKLRK..ELSDLAIA...HE.YGEepcgrytrlkqqldnlnei..............................................................................................cqktrkytsqaatitakpqtT----.----..--Apqqldaime...................................................................................................rlqldqgqpaQQAL.DTL.IEESTTY...A.E......................DIA.KLRQK..L.DDFRINLELEKRQWCAEKDKV.LGYQKQL.QAHYIHMYQKLRCLD----taa......................................................
LZTS3_MOUSE/465-665                   ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLSEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFG.SKQAS.................LE.LSE.G....ELPPAcl...................kpaLTP...V...DL....VepQE.ALASC...ESD.EAKMRR..QAGVA---...-A.AAS.....................................................................................................................................LVSVD.GEVE..AGG......................................................................................................................EGGT.RAL.RREVGRL...Q.A......................ELA.AERRA..R.ERQGASFAEERRVWLEEKEKV.IEYQKQL.QLSYVEMYQRNQQLERRL-r........................................................
A0A091EAM5_FUKDA/265-463              ..................................................................................................................lr----VC...QKSGE..ISLLKQQLKESQAELVQKGSELVSLR..VAL.R.E.AR....AALRVSEG.R.A.RGLQ....EAAR.ARELE.................LE.TCS.Q....ELQRH........................RQE...A...ER....L..RE.KAGQL...DME.AAGRKL..RDREAELQ...QL.RDS.....................................................................................................................................LEESE.ATVC..QRH......................................................................................................................RQEA.ERL.REKAGQLdmeA.A......................GLR.EPSVP..P.PAADPFLLAESDEAKAEKEQV.IRYQKQL.QHNYIQMYRRNRQLEQELQ.........................................................
G3WS80_SARHA/452-540                  ................................................................................................pgelpdggcetddsksqglr------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................---G.EAG.SSGAERL...W.S......................ELQ.RERQQ..G.REQALLFEQERRTWQEEKNRV.LRYQREI.QVSYMEMYHRNQTLEQEL-r........................................................
E2QZ04_CANLF/366-450                  ...................................................................................................................a-RWEVC...QKTAE..ISLLKQQLREAQAELAQKLAEIFSLK..TQL.R.G.SR....AQAQAQDA.E.L.AQLR....EAVR.SLQE-.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------qgpreeapggcetddcksr......................................
G5BCC3_HETGA/598-689                  .........................................................................................reeapgscetddcksrgllgeaggses------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.GDGAEQL...R.A......................ELL.QERLR..G.QEQALRFEHERRTWQEEKEQV.LRYQREI.QGGYVDMYRRNQALEQEL-r........................................................
G1MY75_MELGA/403-472                  ....................................................................................................................TKWEVC...QKAAE..ISLLKQQLRDTQEEMAQKLGEIFSLK..TQL.R.E.AK....AEVQARDS.Q.L.AQLA....DSLQ.S----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------paepgts..................................................
A0A0P7W879_9TELE/397-612              ....................................................................................................................TKWEVC...QKSGE..ISLLKQQLKDLQAELSQRTGEIIALK..AQL.R.E.AR....AELQAGEA.R.A.QEAR....AAAR.TRTLE.................LE.VCE.N....ELQRR........................KSE...A...EL....L..RE.KAGRL...EEE.SARLRE..ALGQCRGS...TP.SPGrglglsps....................................................................................................................hreaeellaCESDE.AKVQ..RQS.....................................................................................................................sSTGL.QGL.RQQVERL...R.A......................ELM.FERRH..S.EEQLGAFEEERRVWQEEKEKV.IRYQKQL.QQNYVQMYQRNRELERVM-r........................................................
F6Q1N3_MACMU/392-592                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLSEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFS.SKQAS.................LE.LGE.G....ELPAAclk.................paltPVD...P...AE....P..QD.ALATC...ESD.EAKMRR..QAGVAA--...--.AAS.....................................................................................................................................LVSVD.GEAE..AGG......................................................................................................................ESGT.RAL.RREVGRL...Q.A......................ELA.AERRA..R.ERQGASFAEERRVWLEEKEKV.IEYQKQL.QLSYVEMYQRNQQLERRL-r........................................................
H2QJV4_PANTR/438-638                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLSEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFS.SKQAS.................LE.LGE.G....ELPAAclk.................paltPVD...P...AE....P..QD.ALATC...ESD.EAKMRR..QAGVAA--...--.AAS.....................................................................................................................................LVSVD.GEAE..AGG......................................................................................................................ESGT.RAL.RREVGRL...Q.A......................ELA.AERRA..R.ERQGASFAEERRVWLEEKEKV.IEYQKQL.QLSYVEMYQRNQQLERRL-r........................................................
W5JXG9_ASTMX/294-535                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLRDSQGEVTQRAGEMVALR..NQL.K.E.LN....AQLREREE.A.E.LSLK....ESFC.TKTLE.................LE.RCE.A....ELQAM........................LAE...V...SV....L..RD.KLSAF...ETE.VAGLKK..ALSELSHT...AN.ARApehslaemgqlvlsrsrerllsp......................................................................................lsrlpalpplpapaslpgadpllsLQSDD.SKAQ..RQE......................................................................................................................---A.GDL.RRQLELL...Q.G......................ELR.LERQQ..R.ERQALSFAQERQTWQGEKDRV.LKYQAQL.QLSYVEMLQKNQALEERV-d........................................................
H2ZMH5_CIOSA/25-218                   ...................................................................................................................s-EWERQ...QKYGE..LSMLKSQLKDIQAESAQRGSEIVALR..TRN.R.E.LQ....ALVARRDA.E.A.VDLN....EKLN.DRNLE.................IG.ELE.Q....RLSEA........................SSP...A...GT....W..HR.SPGSI...SP-.-QSLRN..PSGTFSEP...NS.GN-.....................................................................................................................................WHDDRnYLSS..SSP......................................................................................................................PGAL.TSL.KR--DEL...I.K......................RLY.EAEAR..C.NEQEKFFNIERRQWADDKSRV.IRYQKQL.QANYVQTYKRCGALEREVK.........................................................
G3V8V8_RAT/468-668                    ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLSEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFG.SKQAS.................LE.LSE.G....ELPPAcl...................kpaLTP...V...DL....VepQE.ALASC...ESD.EAKMRR..QAGVA---...-A.AAS.....................................................................................................................................LVSVD.GEVD..AGG......................................................................................................................EGGT.RAL.RREVGRL...Q.A......................ELA.AERRA..R.ERQGASFAEERRVWLEEKEKV.IEYQKQL.QLSYVEMYQRNQQLERRL-r........................................................
B4L2X2_DROMO/489-736                  ...................................................................................................................s-EWKVC...ERNGE..IALLKTQLKEAHLEINMKDHTILSLR..HSN.M.NsSN....NNNNNNNN.N.N.NNCQ....TTTC.QSQPK.................QQ.AKE.A....QQQKDpeqeq..............qlqqlNKI...I...AL....K..DQ.VIGAL...TNE.LAKLRK..ELSDLAIA...HE.YGEepcgrytrl...................................................................................................................kqqldnlneICQKT.HKYT..RQA......................................................................................................................AAGP.MQL.DAIMERL...Q.LdqgqpaqlaldtlieesttyaeDIA.KLRQK..L.DDFRINLELEKRQWCAEKDKV.LGYQKQL.QAHYIHMYQKLRCLD----naa......................................................
G3IJ68_CRIGR/219-416                  ....................................................................................................................TKWEVC...QKSGE..ISLLKQQLKESQAELVQKGSELVALR..VAL.R.E.AR....AALRVSEG.R.A.RGLQ....EAAR.AREVE.................LE.ACS.Q....ELQRY........................RQE...A...ER....L..RE.KAGHL...DAE.AAGLRE..PPVPPATT...DP.FLL.....................................................................................................................................AESDE.VKVQ..RAA......................................................................................................................AGAG.GSL.RAQVERL...R.Q......................ELQ.REQRR..G.DEQRDSFEGERLAWQAEKEQV.IRYQKQL.QHNYIQMYRRNRQLEQELQ.........................................................
L9JR66_TUPCH/380-566                  ....................................................................................................................TQWEVC...QKSGE..ISLLKQQLKESQTEVTAKASEILSLK..AQL.K.D.TR....GRLEGLER.K.T.QDLE....GALR.TKGLE.................LE.VCA.N....ELQRK........................KNE...A...EL....L..RE.KVNLL...EQE.LLELRA..QAAVQR--...--.---.....................................................................................................................................---DS.-AAL..GPT......................................................................................................................FEDV.PAL.QRELERL...R.A......................ELK.EERQG..H.EQMSSGFQQERLVWKGEKEKV.IHYQKQL.QQSYLAMYQRNQRLEKAL-q........................................................
H0UV36_CAVPO/397-528                  ....................................................................................................................TKWEVC...QKSGE..ISLLKQQLKESQAELVQKGSELVSLR..VAL.R.E.AR....AALRVSEG.R.A.RGLQ....EAAR.ARELE.................LE.TCS.K....ELQRH........................RQE...A...ER....L..RE.KAGQL...DLE.VAGLRE..PSVPPATA...DP.FLL.....................................................................................................................................AESDE.AKVQ..RAA......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------agaggr...................................................
A0A096P6A7_PAPAN/439-636              ....................................................................................................................TKWEVC...QKSGE..ISLLKQQLKESQAELVQKGSELVALR..VAL.R.E.AR....ATLRVSEG.R.A.RGLQ....EAAR.ARELE.................LE.ACS.Q....ELQRH........................RQE...A...ER....L..RE.KAGQL...DAE.AAGLRE..PAVPPATA...DP.FLL.....................................................................................................................................AESDE.AKVQ..RAA......................................................................................................................AGVG.GSL.RAQVERL...R.V......................ELQ.RERRR..G.EEQRDSFEGERLAWQAEKEQV.IRYQKQL.QHNYIQMYRRNRQLEQELQ.........................................................
M3WIT6_FELCA/470-548                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLSEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFG.SKQAS.................LE.LGE.A....ELP--........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------aaw......................................................
L8Y8Q9_TUPCH/401-481                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLSEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFG.SKQAS.................LE.LGE.G....ELP--........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------aaclt....................................................
F6U316_MACMU/380-565                  ....................................................................................................................TQWEVC...QKSGE..ISLLKQQLKESQTEVNAKASEILGLK..AQL.K.D.TR....GKLEGLEL.R.T.QDLE....GALR.TKGLE.................LE.VCE.N....ELQRK........................KNE...A...EL....L..RE.KVNLL...EQE.LQELRA..QAALARDM...--.---.....................................................................................................................................-----.--VP..PTF......................................................................................................................PEDV.PAL.QRELERL...R.A......................ELR.EERQG..H.DQMSSGFQHERLVWKEEKEKV.IQYQKQL.QQSYVAMYQRNQRLEKAL-q........................................................
F7GB08_ORNAN/379-443                  ...................................................................................................................e------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.---LARL...R.D......................SVR.VLRDPgtR.QDVALLFERERRTWQEEKDKV.LRYQREI.QVSYMEMYHRNQALERQL-r........................................................
A0A0H5S858_BRUMA/656-827              ...............................................................................................................kerlw------...-----..-------------------------K..EQL.A.D.LK....QKLQASQQ.G.E.NALR....QQIQ.RCNEE.................RE.QFR.S....TIQNL........................TSD...K...QG....L..QR.KCLQL...ERE.FFQLRE..CFDELIRN...RD.ETVcgpcrkrit..................................................................................................................cyitaantnnS----.----..--Iadkrvrpp.....................................................................................................lpapryskeSSSE.REL.RNEVDEL...R.G......................EVS.TLRDT..L.NEQIGLFADERKRWEEERIKI.LK-----.-------------------ssn......................................................
W5N4H0_LEPOC/427-650                  ....................................................................................................................TKWEVC...QKSGE..ISLLKQQLKELQTDLGQKASEIVALK..AQL.R.E.AR....GELQASQA.H.T.QEVH....AAAR.TRTLE.................LE.VCE.N....ELQRR........................KSE...A...EL....L..RE.KVGRL...EEE.SARLRE..ALGMPGGQ...GM.--Algpapggrgpglsp.........................................................................................................lmgpvyreeeqllaYESDE.AKAQ..RLS......................................................................................................................ADAL.LGL.KQQVERL...R.A......................ELM.YERRR..S.EDQLEAFEDERRVWQEEKEKV.IRYQKQL.QQNYIQMYRRNRELEHVM-r........................................................
G1T8Q8_RABIT/340-508                  ....................................................................................................................TQWEVC...QKSGE..ISLLKQQLKESQMEVSAKASEILGLK..AQL.K.E.AR....GKLEGTEL.K.T.QDLE....GALR.TKGLE.................LE.VCE.N....ELQRK........................KNE...A...EL....L..RE.NVSLL...EQK.LLG---..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................-EDI.PAL.QRELERL...R.A......................ELR.EERQG..H.DQLSSGFQHERLVWKEEKEKV.IQYQKQL.QQSYLLMYQRNQRLEKAL-r........................................................
F6X1P4_XENTR/386-467                  ..................................................................................................................ts--CDIS...QKAGE..ISLLKQQLRDSQAEINVKLGEVVSLK..TQL.R.E.AK....ALVKEKEK.E.S.DELS....TRLQ.VL---.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------edaksqapvdlprdssdt.......................................
I3N9U1_ICTTR/363-446                  ...................................................................................................................a-RWEVC...QKTAE..ISLLKQQLREAQAELAQKLAEIFSLK..TQL.R.G.FR....AQAQAQDA.E.L.ARLR....ETVR.SLQEQ.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.-------...-.-......................---.-----..-.---------------------.-------.-------------------apreeapgscetddcks........................................
F7F202_CALJA/425-625                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLSEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFS.SKQAS.................LE.LGE.G....ELPAAcik.................paltPVD...P...AE....P..QD.ALATC...ESD.EAKMRR..QAGVAA--...--.AAS.....................................................................................................................................LVSVD.GEAE..AGG......................................................................................................................ESGT.RAL.RREVGRL...Q.A......................ELA.AERRA..R.ERQGASFAEERRVWLEEKEKV.IEYQKQL.QLSYVEMYQRNQQLERRL-r........................................................
H2P1D1_PONAB/409-609                  ....................................................................................................................TKWEVC...QKAGE..ISLLKQQLKDSQADVSQKLSEIVGLR..SQL.R.E.GR....ASLREKEE.Q.L.LSLR....DSFS.SKQAS.................LE.LGE.G....ELPAAclk.................paltPVD...Q...AE....P..QD.ALATC...ESD.EAKMRR..QAGVAA--...--.AAS.....................................................................................................................................LVSVD.GEAE..AGG......................................................................................................................ESGT.RAL.RREVGRL...Q.A......................ELA.AERRA..R.ERQGASFAEERRVWLEEKEKV.IEYQKQL.QLSYVEMYQRNQQLERRL-r........................................................
M3ZKX2_XIPMA/456-653                  ....................................................................................................................TKWEVC...QKSGE..ISLLKQQLKEIQSELSQKAGDIVVLK..AQL.R.E.AR....SELQSSQG.R.T.QEAQ....TALR.TRSLE.................LE.VCE.N....ELQRR........................KSE...A...EL....L..RE.KVSRL...EDE.SGRIRD..TLSNHSGN...AP.KWG.....................................................................................................................................GESDE.AKAQ..RQN......................................................................................................................AETL.MGL.RQQVDRL...K.A......................ELM.YERRT..G.EEQRSRFEEERRVWHEEKEKV.IRYQKQL.QQNYIQMYRRNRDLERVM-r........................................................
A0A0H5SM24_BRUMA/361-567              ............................................................................ivdyetiirdkeneltnvratmeqneevvvkvylekerlw------...-----..-------------------------K..EQL.A.D.LK....QKLQASQQ.G.E.NALR....QQIQ.RCNEE.................RE.QFR.S....TIQNL........................TSD...K...QG....L..QR.KCLQL...ERE.FFQLRE..CFDELIRN...RD.ETVcgpcrkrit..................................................................................................................cyitaantnnS----.----..--Iadkrvrpp.....................................................................................................lpapryskeSSSE.REL.RNEVDEL...R.G......................EVS.TLRDT..L.NEQIGLFADERKRWEEERIKI.LK-----.-------------------ssn......................................................
A0A087XCF1_POEFO/471-544              .........................................................................................................dpksagssggp------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-----.----..---......................................................................................................................----.---.--TEERL...R.A......................ELL.LERRQ..S.EAQATAFEEERNTWQTEKDKV.IRYQKEL.QASYLEMYHRNEALERELQ.........................................................
A0A0K0JBZ6_BRUMA/347-531              ..................................................................................................eqneevvvkvylekerlw------...-----..-------------------------K..EQL.A.D.LK....QKLQASQQ.G.E.NALR....QQIQ.RCNEE.................RE.QFR.S....TIQNL........................TSD...K...QG....L..QR.KCLQL...ERE.FFQLRE..CFDELIRN...RD.ETVcgpcrkrit..................................................................................................................cyitaantnnS----.----..--Iadkrvrpp.....................................................................................................lpapryskeSSSE.REL.RNEVDEL...R.G......................EVS.TLRDT..L.NEQIGLFADERKRWEEERIKI.LK-----.-------------------ssn......................................................
I3KMM6_ORENI/491-587                  ......................................................................................................gtqrhrrpsqaahe------...-----..--------------------------..---.-.-.--....--------.-.-.----....----.-----.................--.---.-....-----........................---...-...--....-..--.-----...---.------..--------...--.---.....................................................................................................................................-DEKE.AEEN..PSA......................................................................................................................RAIG.GCG.GPTEERL...R.A......................ELL.LERRQ..S.EAQAMAFEEERHTWQTEKDKV.IRYQKEL.QASYLDMYHRNEALEREVQ.........................................................
G1PNF0_MYOLU/440-637                  ....................................................................................................................TKWEVC...QKSGE..ISLLKQQLKESQAELVQKGSELVALR..VAL.R.E.AR....AALRVSEG.W.V.RGLQ....EAAR.ARELE.................LE.ACS.Q....ELQRH........................RQE...A...ER....L..RE.KAGQL...DTE.AAGLRE..PPVPPATA...DP.FLL.....................................................................................................................................AESDE.AKAQ..RVA......................................................................................................................AGVG.GSL.RAQVERL...R.A......................ELQ.QERRR..G.EEQRDSFEGERLAWQAEKEQV.IRYQKQL.QHNYIQMYRRNRQLEQELQ.........................................................
I3N8Y9_ICTTR/384-575                  ....................................................................................................................TQWEVC...QKSGE..ISLLKQQLKESQTEVNAKASEILSLK..AQL.K.D.AR....GRLEGMEL.K.T.QDLE....SALR.TKGLE.................LE.VCE.N....ELQRK........................KNE...S...EL....L..RE.KVNLL...EQE.LLELRA..QAALQRES...AA.L--.....................................................................................................................................----G.PAVT..PTF......................................................................................................................SEDI.PAL.QRELERL...R.A......................ELK.EERQG..H.DQMSSGFQQERQVWKEEKEKV.IQYQKQL.QQSYLAMYQRNQRLEKAL-q........................................................
#=GC seq_cons                         .....................................................................................................................pWEVC...QKsGE..ISLLKQQL+-uQs-lspKhuEllsL+..spL.+.-.s+....uplptp-t.p.h..tLp....pshp.spp.p.................hc..hp.t....pl.th..................................t........pt.........p.p...th+t..............................................................................................................................................................................................................................................................................................t.h..th.ptphcpL...p.s......................EL...ERpt..t.pp.h.tFptERhsWppEK-+V.lcYQ+pL.Q.sYlpMap+NptLEp.l.p........................................................
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