#=GF ID   Fibrillarin_2
#=GF AC   PF10113.4
#=GF DE   Fibrillarin-like archaeal protein
#=GF AU   COGs, Finn RD, Sammut SJ
#=GF SE   COGs (COG4018)
#=GF GA   25.00 25.00;
#=GF TC   534.40 534.20;
#=GF NC   18.10 17.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR016760;
#=GF CC   Members of this family of proteins include archaeal fibrillarin
#=GF CC   homologs.
#=GF SQ   30
#=GS A4G066_METM5/1-510  AC A4G066.1
#=GS A6UVT4_META3/1-510  AC A6UVT4.1
#=GS Q6M0Z3_METMP/1-510  AC Q6M0Z3.1
#=GS Q50530_METTF/1-505  AC Q50530.1
#=GS Q8TZB8_METKA/1-511  AC Q8TZB8.1
#=GS H1KYF3_9EURY/1-506  AC H1KYF3.1
#=GS Y1137_METTH/1-505   AC O27209.1
#=GS D9PY01_METTM/1-505  AC D9PY01.1
#=GS D2ZN22_METSM/1-500  AC D2ZN22.1
#=GS F0S2C3_DESTD/1-505  AC F0S2C3.1
#=GS G0H1D2_METMI/1-510  AC G0H1D2.1
#=GS E3GYZ0_METFV/1-505  AC E3GYZ0.1
#=GS Y787_METJA/1-503    AC Q58197.1
#=GS D7DV43_METV3/1-511  AC D7DV43.1
#=GS C9RE92_METVM/1-503  AC C9RE92.1
#=GS D3S5E9_METSF/1-504  AC D3S5E9.1
#=GS A5UKP8_METS3/1-500  AC A5UKP8.1
#=GS F8ALF2_METOI/1-511  AC F8ALF2.1
#=GS C7P8C9_METFA/1-504  AC C7P8C9.1
#=GS A2SUA0_METLZ/1-506  AC A2SUA0.1
#=GS Q50517_METTF/1-505  AC Q50517.1
#=GS D3E193_METRM/1-502  AC D3E193.1
#=GS A6VIB4_METM7/1-510  AC A6VIB4.1
#=GS B9AGL1_METSM/1-500  AC B9AGL1.1
#=GS E1RJE5_METP4/1-505  AC E1RJE5.1
#=GS A6URA8_METVS/1-510  AC A6URA8.1
#=GS F6BDV5_METIK/1-506  AC F6BDV5.1
#=GS D5VRR8_METIM/1-493  AC D5VRR8.1
#=GS Q2FR47_METHJ/1-505  AC Q2FR47.1
#=GS A9A8H1_METM6/1-510  AC A9A8H1.1
A4G066_METM5/1-510             MKELITNSLN.DLDSAMELRELVINkinnqklTESDIIEIVDTVDDLNFEDTQKLGSIFRRFPLGCDILEIGVGPCASSLTLPQFIENCVLTEHMGFPIHLCGYALADIAEKEGLTPIAVMNEVYNNVEVPLDLDHFGRFGPMRFPKEISHCMGDCYYNGPPYKGCPRDRIHKRLTTKEREYSSEVADWIKKSATVCVNVVEEQG..ACDHGADISEMEDVSKAAHKFGRGVEGIFHIGDGYEELISGLKACN.DLEVDALVVEGGPFNRSKDRLKDFAKAVAVSRILVKGGVVATNGAYEDECRVGLRSGLNVILSGFSGNHHGYMCGHNIKEARRNNFGLPRVLKIMKEE-.AE.KINICIANRELLKVLAKSSRFLNYKgnhMIYPS.MIGDYFMGDAHW.VAVTNSGMYNSPY..FGKTLDSL....EEEL.NCDKVGVLGGRYISWSIADTLK--.PEELYVSDVDPWVEHATVKILNDN-GINAYACNGSDKKALESADKSVITTMIPEILIRIRNKF-.DAISLI........
A6UVT4_META3/1-510             MHDIIKSAVN.DLDACLELRGLITNkltnnklTEGDIISVVDAVGELPIEDIQKIGSNLRKFPLGCDLVEIGIGPCSSSLTMPQLVENSMLSDYMGFPIHICAYALGDIAERESITPLEVFKTISESVEVPIDLDHFGKYGAMRFPKEITHCGGDCYRMGAPSEGCPRGRIHKRLIDKEKEYSYEFNDWIKLSSTVCINVVEEQG..GEEHGAPLEEMKIVANEAHKHGKGLEGIFHIGDGYDDLITGLKSCV.DLGVDAFVVEGAPFNRAKDRLKTFAKAIAVSRILVKGGVVATNGAYEDECRIGLRSGLNMILSGFSGNHHGYMCGYSPDTAKRGNFGAPRVLRIIKEEIeYN.KLDTCLLTKPVLRALTKSAKFLNYGgnsLIYPN.KIGDFFTGDAHW.VAVNNSNLANNLH..-TKTIDDI....---E.KVDKIGALGGRYVAWGLIDALK--.PEEVYISDANKWVEYATIKILNDA-GINAYGTDGNDKKVIEQADKSFITSFIPEINLKIKNRYN.K-----dvesli..
Q6M0Z3_METMP/1-510             MKELIKNSLN.DLDSAMELRELVINkinnqklTESDIIEIVDTVDDLSFEDTQKLGSIFRRFPLGCDLLEIGVGPCSSSLTLPQFIENCVFTDHMGFPIHLCGYALADIAEKEGLTPIEVMNEVYNNVEVPLDLDHFGRFGPMRFPKEISHCMGDCYYNGPPYKGCPRDRIHKRLITKEREYSNEFGEWIKKSATVCVNVVEEQG..GGDHGADISEMEDVAKAAQKFGRGVEGIFHIGDGYEDLITGLKACN.DLDVDVLVIEGGPFNRSKDRLKDFAKSVAVSRILVKGGVVATNGAYEDECRVGLRSGLNVILSGFSGNHHGYMCGYNIKEARRNNFGLPRVLKIMKEE-.AE.KINICIANRELLKVLARSSRFLNHNenhLVYPS.MIGDYFIGDAHW.VSITNSKMYNAPY..FGKTLDSL....EEEL.NCDKVGVLGGRYISWGIADALK--.PEELYVSDVDPWVEHATVKILNDN-GINAYACNGNDKKALESAEKSVITTMIPEIVLRIKNKF-.DAVSL-l.......
Q50530_METTF/1-505             MHDIIREAIN.DPEAAWEIIKM---.......-DRNVTEVVDAVSDLSREDKIKLGATFKRFPLGCDLTELIVGTCASDLERMDLLGNCMVADAIGATIHVCAYAFADIAENYGMRPVELMREVREITEVPLDLDHFGRYGPMRFPPSITGCGGQCYLEGPPFQGCPRERIHSRLIDREKEGLPDREEWVELASSVAVNLTPVQG..ADTHAAPLREAEEVLEIARKHGKGVEAIMFVGDGYEDLISGFEAGL.EMGVDVFVIEGGPFNLAGNRLDAFAGAVAAARILTPGKIVATNGAYEDECRIGLRAGLNAIITGFPRNHHGYMCGYSPGTARRGRFGLPRVMKIMRDEV.PA.GLTPVPVQKPQLEALAAAVKASGTE...NVYPE.RIGYTYVGDAHW.ACLPSTPIYERVR..VKRDVNGLvemaEAGE.ISGTVAVFGATFVSWVIAKKLDGL.VDEFILVDRDPWVESVTVDNLSSELKSGVHGGGSDDRRAYELADSSVISTTIPQISAGISEKFT.DAITLV........
Q8TZB8_METKA/1-511             MLDLLHEACE.SLDAALELKRLAYE.......GKLSVDEVVTDLGELTDRELEALGDNLRTFPMGCDLIELAVGPCASDYSPDVLLANAILADRMGLPLHVCAYAVADVAENYGMRPIELFRRLVRNVRVPVDVDHIGAHGPMRFPRDITACEGTCYLEGPPFKECPRGRIHRRLIDKERQQGEDLEEWAELAASICVNVTGEGGqdAEAHAAPLDEMKRVAETARHSGAGVGAILHVADGEDEFADGLKAAVeEVKADYLAVEGGPFNRAEDRLSAFRRAVVACRVFAPGKVVLTNGAYEDELVVGLRAGLNGALSGFPKNHHGYMVGYEPGTARRGKFGLPKVLAIMRKTLgSRyGNTKVPAGWEELEGITRAALFLGSN...LLYPR.DVAGIPIGDVHWvAALRSNAARELSD..EVRSVEEV....ASEV.DADTVALLGGRFPAWGLALTLDELgVSEVLISDPDAWVERATVRLLDEELDATVHAMAGDDRKAVKEADAAFVTAVMPGIAERLAERTG.-AMTVC........
H1KYF3_9EURY/1-506             MRELIKDAIN.DLNAALELRKLIIKklnenkiKESNIIEIVDAVDDLSIEEIQKLGSNLRKFPMGCDLVEVVVGPCASSLTLNQFVENCILTDYMGFTIHACAYALADIGEKEGIPPLEVMKMVYENVDVPLDLDHFGQYGAMRFPKEITHCMGECYYKGPPYKGCPRKRIHKRLIDKEKEYAHEFEDWIKLASTVCINVVEEQG..GEEHAAPLEEMAVVAKTAKKYGKGLEGIFHVGDGYDDLITGLKSCI.DFDVDVLVVEGAPFNRAKDRLKAFAKAIGVSRILVKGGVVATNGAYEDECRIGLRSGLNVIISGFSGNHHGYMCGYSPGTAKRGNFGLPRVMRIIKEEI.-K.NMDVTLVSRHDLIAIARSSKFLG-N...VVYPE.TLGGMFIGDAHW.VAIKNSKLHDKVG..IRKTLEDV....ENEY.NGEKLGFLGGRYIAWGIAKKLM--.PEEVYVSDANKWVEEATVKILNEV-GINAYKCNGNDEEVVKNADKTYICSMIPEIILKIKNKVE.-AES--lm......
Y1137_METTH/1-505              MHELIREAVD.NPGTAWEIIKM---.......-DRDVTEVVDAVSDLSREDKIKLGATFKRFPLGCDLTELIVGTCASDLEKIDLMGNCMLSDTIGATIHVCAYAFADIAESYGMRPVELMREVRETTEVPLDLDHFGRYGPMRFPRSITGCGGQCYLEGPPFEGCPRERIHARLLDREKEGLSDREEWVELSSSVAVNLTPVQG..AETHAAPLEEAEEVLELARKHGKGVEAIMFVGDGYDDLISGFEAGL.EMGVDVFVLEGGPFNLAGDRLDAFAGAVAAARILTPGKIVATNGAYEDECRIGLRAGLNAIITGFPKNHHGYMCGYTPGTARRGKFGLPRVMKIMREEV.ES.GLTPVPIQKAQLEALAAAVKVSGTE...NVYPR.TLGYTYVGDAHW.ACLPSTPLYERVE..VKRDVNALvkmaEDGD.IHGRVAIFGARFVSWVIADKLDGL.VDEFVIVDRDPWVEQVTVDNLRSELRTDVHPGNSDDEGAYSSADSSIVSTTIPQISAKISGKFR.DTVTLV........
D9PY01_METTM/1-505             MHDIIREAVD.NPEAAWEIMKM---.......-DRDVTEVVDAISDLSREDKIKLGATFKRFPLGCDLTEIIVGTCASDLERMDLIGNCILSDTIGATIHVCAYAFADIAENYGMRPVELMREVRETTEVPLDLDHFGRYGPMRFPRSITGCGGQCYLEGPPFEGCPRERIHSRLLEKEREGLPDRDEWVELASSVAVNLTPVQG..AETHAAPLDEAREVFELARKHGKGVEAIMFVGDGYDDLISGFEAGL.DMGVDVFVLEGGPFNLASDRLDAFAGAVAAARILTPGRIVATNGAYEDECRIGLRAGLNAIITGFPKNHHGYMCGYSPGTARRGKFGLPRVMKIMREEV.EA.ALTPVPVQKPQLEALAAAVKASGRE...NVYPE.TIGHTYVGDAHW.ACLPSTPLYERVN..IERDVDTLaemtRNGD.IHGTVAIFGARFVSWVIAKKLDGM.VDEFVLVDSDPWVEWVSVDNLRSEIKTEVRCGGSSDADAYRDSDSAIVSTTIPEIAAKISGKFR.DAVTLV........
D2ZN22_METSM/1-500             MYDLIKEAIV.DDDAAIELSKM---.......-DKNVVEVVDAISELSLEDTMKLGMKFKRFPLGCDLTEAVVGTCASDLELMELLGNCRLSDMLGLPIHICAYAFADIAEKHGMRGIEVMRKVYDSVDVPLDLDHFGENGPMRLPQNIVGCGGECYNKGPVYTECPRDRIHERLIDKEKAESSDKEEWVKLSSSVAINLTSEQT..GEGHAAPYREAEDIANLAKKYQRGLEAIMFIGDGYDDLITGFEKAI.GIGADVFVLEGGPYNGAKNPVEAFAKAVAASRILCPGKVVGTNGAYERECRIGLRSGLNVIITGFPKNHHGYMCGYEPGTARRGKFGLPRIMQIMKEEV.HN.PNVQVPVLKEDLIPLTTAIKIAGRD...YIYPK.KIGAYTVGDAHW.ATLINSKMYKNLT..LKNDLNDI....VNSV.NGNSVALLGGRFLSWVIANELDKQ.VDEIIISDADPWVQRMTVENLQDALDATIIPGDGDVNSAK-QADSSIISSTVPGISNKILNKVP.NAFNI-v.......
F0S2C3_DESTD/1-505             MKELIYRTIQgDINSQYILYKK---.......AKEEIQKLFENIKKLSDGELIALGQRFKEFPFGCDLNEIMVDVVSLKQEIDEIRGGFRLVDRLGFPIHVCSYVVAELAEREGKTPLELMKELRALTSMPIDIDHFGQFGPMRYPEEIAKCPAYCYRSGKPFNGCPRGRIHKRLIEKERCFAKEKEGWSELVQSISVSLMAFQK..NTVHAASPEETLKVIDFAKSKKKGVGAIICVGNGKDELLRGLKACI.KHSIDEIVIEGGPYNTAPNRVRAFGETVVMARIIAPGKIVATNGQYEDELRFGLKCGLNSVISGFPGNHHAYMSGYKPEKATIDRFGLPKIIELMAQEL.KD.SPFPIPADRESAIVIAKSAKFLGKE...TIYPNgKLGDIYIGDAHW.FLLLNSPLAQGIN..IKWSLELLt.efIRKN.KFKKVGLLGGRFIAWGIAKAIDPF.VKEILVSDKDKRIENTTVKVFKEYLSSKITRCNGNDDMCIKNSEITVLCSFIPSFIRKFK----.------giqkvitl
G0H1D2_METMI/1-510             MKELIKNSLN.DLDSAMELRELVINkinnqklTESDIIEIVDTVDDLSFEDTQKLGSIFRRFPLGCDLLEIGVGPCSSSLTLPQFIENCVFTDHMGFPIHLCGYALADIAEKEGLTPIEVMNEVYNNVEVPLDLDHFGRFGPMRFPKEISHCMGDCYYNGPPYKGCPRDRIHKRLITKEREYSNEFGEWIKKSATVCVNVVEEQG..GGDHGADISEMEDVAKAAQKFGRGVEGIFHIGDGYEDLITGLKACN.DLDVDVLVIEGGPFNRSKDRLKDFAKSVAVSRILVKGGVVATNGAYEDECRVGLRSGLNVILSGFSGNHHGYMCGYNIKEARRNNFGLPRVLKIMKEE-.AE.KINICITNRELLKVLARSSRFLNHKenhLVYPS.MIGNYFIGDAHW.VSITNSKMYNAPY..FGKTLDSL....EEEL.NCDKVGVLGGRYISWGIADALK--.PEELYVSDVDPWVEHATVKILNDN-GINAYACNGNDKKALESAEKSVITTMIPEIVLRIKNKF-.DAVSL-l.......
E3GYZ0_METFV/1-505             MHDIVKEAVN.NLDAAWELAKM---.......-KKTPEEIVDAVSDLSREETMQLGKNFKRFPIGCDLTEILVGACASDIKKIDLLGNCIVADMLGASIHVCAYAFADIAENYGMRGVDLVKEVRELVDVPLDIDHFGKYGPMRFPSDITRCWGQCYYEGPPFKECPRGRIHKRLLEKEKKGIKERDEWIKLASSVAINLISVQG..GEAHAAPLDEAIEVAKLTKKYGRGLEAIMCVGDGYEDLIKAFEAAL.EIGVDVFVIEGGPFNQAKDRLDAFARAITCARILAPGKVVGTNGAYEDECRIGLRSGLNAIITGFPKNHHGYMCGYSPGTARRGNFGMPRVIKIIKEEV.KN.GLTRAPIQKDELIALTKSVKVIGKE...NIYPN.KIGYTTVGDAHW.VCVSLTPLYEKLH..VNKTVDDIvkmaENGL.IGEKVALLGGRFIAWVLAKKLDKY.VDQILISDVDPWVEKITVENLRSEIKADVHRAHSNDKEAYNESDATIISSTIPGVVRKLTKKLP.ESVALI........
Y787_METJA/1-503               MRELIKEAVN.SLDSALELRKLIIKklnekklKESDIIEIVDAVDDLSLEEIQKLGSNLRTFPMGCDLVEIAVGPCSSSLTLIQFIENCILTDYMGFPIHICSYAVADIAEKEGLKPIEVLKMVLENVDVPIDIDHFGMYGPMRFPKEITHCYGDCYFKGPPFKGCPRNRIHKRLIEKEKEHADEFEDWIKLASTLCINVVEEQG..GEEHAAPLEEMKIVAETAKKYGKGLEGIFHIGDGYDDLITGIKACI.DLDVDVFVVEGAPFNRAKNRLKAFAKAIAVSRILVKGGVVATNGAYEDECRVGLRSGLNTILTGFPLNHHGYMCGYSPKTAKRGNFGLRRVMRIIKEEIrAG.NVNATFIDKDMVKAIALGNRFLKGN...-IYPY.SIGGFYLGDAHW.AAIKESNLCKKLK..INKTIDDI....----.SAEKVGLIGGRYISWAIAEK----.AEEVYISDTDSWVEKATIKILNEA-GINAYPCNGDDKKVLE-ADKAYITTFIPNIALKILNKLR.DSKV--ell.....
D7DV43_METV3/1-511             MKELIKDSIN.DPMAALELKGIINNklirnklKESDIIEIVDVLGNFELEELYKIGNNFRKFPMGCDLVELGVGPCSSTLDLRQFLENCTLTDHMGFPIHLCAYAIADIAEKESMTPFEVMEKIYNLVDVPLDLDHFGENGPMRFPKEITHCMGECYNQGPPYTGCPKDRIHKRLLDKEHKYAYEFENWIKKSSTVCVNVVKEQG..GEEHSASIDEMEKVVKASKKFGKGIEGIFHIGDGYDDLITGLTACN.DLDVDVFVVEGGPFNRSNDRLKDFAKSIVASRILVRGGVVATNGAYEDECRVGLRSGLNVILTGFVGNHHGYMCGYAPGTAKRTNFGLPRVLSIVKEEL.-S.NLNICLATKTQLEAIAKGNKFLTYNdktYIYPE.TVGNYFMGDAHW.TTVKDSNLGRKPY..FGKNLTSL....GEELgNYDKLGLLGARYISWGIANNLN--.PEEVYISDMDPWVEKATVKILNDN-GINAYACDGNDKKVVENSDKSVITTMIPEIMIKILKKTN.-AIN--lf......
C9RE92_METVM/1-503             MRDLIKEAVN.SLDSALELRKLIIKklnegklKESDIIEVVDAVDDLPLEEIQKLGSNLRTFPMGCDLVEIAVGPCSSSLTLTQFIENCILTDYMGFPIHICSYAVADIAEREGLKPIEVLKMVLNEVDVPIDIDHFGMYGAMRFPKEITHCYGDCYFKGPPFKGCPRDRIHKRLIEKEKEHEDEFEDWIKLASTVCVNVVEEQG..GEEHAAPLEEMKIVAETAKKYGKGLEGIFHIGDGHDDLISGIKACI.DLDVDVFVVEGAPFNRAKDRLKAFAKSIAVSRILVNGGVVATNGAYEDECRVGLRSGLNTILTGFPLNHHGYMCGYSPKTAKRGNFGLRRVMRIIKEEIrAG.NVNASFVDKDIIKAIALGNKFLKGN...-IYPH.NVGGFYLGDAHW.AAIKESNLCRKLK..VNKTIDDI....----.SAEKVGLIGGRYISWAIAEK----.AEEVYISDADSWVEKATIKILNDA-DINAYPCNGDDRKALE-ADKAYITTFIPNIALKILNKLR.DGK---vell....
D3S5E9_METSF/1-504             MRDLIKEAVN.SLDSALELRKLIIEklnekklKESDIVEIVDAVDDLSLEEIQKLGSNLRTFPMGCDLVEIAVGPCSSSLTLTQLIENCILTDFMGFPIHICSYAVADIAEREGLKPIDVLKMILNEVDVPIDIDHFGMYGAMRFPKEITHCYGDCYFKGPPFKGCPRNRIHKRLIEKEKEHADEFEEWIKLASTVCINVVEEQG..GEEHAAPLEEMAIVAKTAKKYGKGLEGIFHIGDGYDDLITGLKACI.DLDVDVFVVEGAPFNRAKDRLKAFAKAVAVSRILVKGGVVATNGAYEDECRVGLRSGLNTILTGFPLNHHGYMCGYSPGTAKRGNFGLRRVVRIIKEEIkAG.NVNATFIDKDMVKAIALGNRFLKGN...-VYPY.NIGGFYLGDAHW.AAIKESNLCRKLR..VNKTIDDI....----.SAEKVGLIGGRYISWAIAEK----.AEEVYISDTDSWVEKATIKILNEA-GINAYPCNGDDKKAVESSEKAYITTFIPNIALRILNKLR.DDK---vell....
A5UKP8_METS3/1-500             MYDLIKEAIV.DDDAAIELSKM---.......-DKNVVEVVDAISELSLEDTMKLGMKFKRFPLGCDLTEAVVGTCASDLELMELLGNCRLSDMLGLPIHICAYAFADIAEKHGMRGIEVMRKVYDSVDVPLDLDHFGENGPMRLPQNIVGCGGECYNKGPVYTECPRDRIHERLIDKEKAESSDKEEWVKLSSSVAINLTSEQT..GEGHAAPYREAEDIANLAKKYQRGLEAIMFIGDGYDDLITGFEKAI.GIGADVFVLEGGPYNGAKNPVEAFAKAVAASRILCPGKVVGTNGAYERECRIGLRSGLNVIITGFPKNHHGYMCGYEPGTARRGKFGLPRIMQIMKEEV.HN.PNVQVPVLKEDLIPLTTAIKIAGRD...YIYPK.KIGAYTVGDAHW.ATLINSKMYKNLT..LKNDLNDI....VNSV.NGNSVALLGGRFLSWVIANELDKQ.VDEIIISDADPWVQRMTVENLQDALDATIIPGDGDVNSAK-QADSSIISSTVPGISNKILNKVP.NAFNI-v.......
F8ALF2_METOI/1-511             MKDIIKNAVN.DLDICLELRKDVIEkitknklSEKEIIEIVDAVDDLSIEEIQKLGSNFRKFPLGCDLVEMGIGPCSSSLTLTELIENCILSDYIGFPIHICAYALGDIAEKEGMTPLEVFKTIHNAIEVPIDLDHFGKYGAMRFPKEITHCMGDCYYNGPPFKGCPKDRIHKRLIDKEKKYSYEFDDWIKLSSTVCVNVVREQG..GEEHAAPLDEMEIVAEAAKKYGKGLEGIFYVGDGYDDLITGLKSCI.DLDVDVFVVEGAPFNRAKDRLKAFAKAVAVSRILVKGGVVATNGAYEDECRIGLRSGLNVILSGFRGNHHGYMCGYSPKTAKRGNFGVPRVLRIIKEEIkNN.KLDTHILNRNILKAIALGSKFLNYKnesLIYPN.SLGGHFIGDAHW.VAAKNSNLYNNINniYNKTIDDI....---D.NCSKLGLLGGRYIAWGIAKALK--.PDEVYISDANKWVEKATVKILNDA-KINAYGCNGNDKKVMENADKSIITSFIPEIVLRIKNKI-.DAESLI........
C7P8C9_METFA/1-504             MRDLIKEAVN.NLDAALELRKIVLKkinekklKESDIVEVVDAVDDLSLEEIQKLGSNLRKFPMGCDLIEIGVGPCSSSLTLTQFIENCILTDYMGFPIHICSYAVADIAEKEGLNPIDVLKMVLENVDVPIDIDHFGKYGPMRFPKEITHCYGDCYFKGPPFKGCPRDRIHKRLIEKEKEHANEFEDWVRLASTVCINVVEEQG..GEEHAAPLDEMEVVAEAAKKYGKGLEGIFHIGDGHDDLITGIKACI.DLDVDVFVVEGAPFNRAKDRLKVFAKAVAVSRILVKGGVVATNGAYEDECRIGLRSGLNTILTGFPLNHHGYMCGYSPGTAKRGNFGLRRVMRIIREEIkAG.NVNASFIDKDVVKAIALGNRFLNGN...-IYPY.SIGGFYLGDAHW.ACIKESNLCKKLN..VNKTIDDI....----.SAEKVGLIGGRYISWAIAEK----.AEEAYISDIDSWVERATIKILNDN-GINAYPCNGDDKKAVENSEKAYITTFIPNIALKILDRIR.DKK---vell....
A2SUA0_METLZ/1-506             MKSLLQDAAN.DPYRAWELVKY---.......-AKNPEQIIEGLTALNREETMHLGMNFKKFPLGCDLTEVFVGTCASDLALQDIYGNCLLSDTIGASIHVCAYAFSDIAEANGMRGIDLMRKIRETTEVPLDLDHFGMYGPMRFPETIVGCPGQCYNQGPPFDGCPRGRIHARLIEKEKEALEDKEEWIKLSSSVAVNLTSIQG..GEEHAASLDEAEDIVKLARKYNKGIEAIMFVGDGYEDLIAGFDAGL.KMGVDVFVIEGGPFNRAKDRLDAFSRAVTAARILAPGKVVATNGAYEDECRVGLRSGLNAVISGFPKNHHGYMCGYSPGTAKRGNFGLPRVMQIIHDEA.AT.QWTHAPIQKGELEALARAVKVVGPQ...NAYPK.VIGATTLGDAHW.ACLSHTPLYRRVT..VNRTINDItqmaENGE.FNETVALLGGRFVSWAVAKALSGK.VDRILISDADPWVENITIENLRSVVDTEICSGNTDDAGSAASADSTIICSTVPEIAGKIQHKIGrNAIT--fi......
Q50517_METTF/1-505             MHELIREAVD.NPGTAWEIIKM---.......-DRDVTEVVDAVSDLSREDKIKLGATFKRFPLACDLTELIVGTCASDLEKIDLMGNCMLSDTIGATIHVCAYAFADIAESYGMRPVELMREVRETTEVPLDLDHFGRYGPMRFPRSITGCGGQCYLEGPPFEGCPRERIHARLLDREKEGLSDREEWVELSSSVAVNLTPVQG..AETHAAPLEEAEEVLELARKHGKGVEAIMFVGDGYDDLISGFEAGL.EMGVDVFVLEGGPFNLAGDRLDAFAGAVAAARILTPGKIVATNGAYEDECRIGLRAGLNAIITGFPKNHHGYMCGYTPGTARRGKFGLPRVMKIMREEV.ES.GLTPVPIQKAQLEALAAAVKVSGTE...NVYPR.TLGYTYVGDAHW.ACLPSTPLYERVE..VKRDVNALvkmaEDGD.IHGRVAIFGARFVSWVIADKLDGL.VDEFVIVDRDPWVEQVTVDNLRSELRTDVHPGNSDDEGAYSSADSSIVSTTIPQISAKISGKFR.DTVTLV........
D3E193_METRM/1-502             MYELIKESIN.SDESALELAKS---.......-KKDVISVVDAISDLSFEDTMKLGTRFKKFPIGCDLTEVVVGTCASDLEKMDLFGNCMLANMIGAPIHICAYAFSDIAEKYGQRGVEIMEEVYNITDVPLDLDHFGKYGAMRFPKHIVGCGGDCYNQGPSFTECPRGRIHERLLDKEKAELDDKETWVQLSSSVAINLSSEQC..NDGHAAPLEEAQDLADLAKKYGKGLEAIMFVGDGYDELITGFTKAI.EMGVDVFVIEGGPFNRCENTNESFAKTIAMSRVLCPGKVVATNGAYESECRAGLRSGLNVIITGFPKNHHGYMCGFEPGTARRGKFGLPRVIKIMNEEI.SA.GPTRVPVQREELLALTHAVKLAGPE...NIYPK.TIGSFAIGDAHW.ATIQNSKMYKEMY..LPKTLEEI....ADSV.NGNSVSLHGGRFVSWLVAKELDKKgIDEIIITDSNPWVEKVSVDNLQEELNATIIRGHADDKGAGMIAKESIVTTTIPKIHNAIKSKIP.HAVNII........
A6VIB4_METM7/1-510             MKELIQNSLN.DLDSAMELREIVINkinnqklTESDIIEIVDAVDDLSFEDTQKLGSIFRRFPLGCDILEIGVGPCASSLTLPQFIENCVLTDHMGFPIHLCGYALADIAEKEGLTPVAVMNEVYDNVEVPLDLDHFGRFGPMRFPKEITHCMGDCYYNGPPYKGCPRDRIHKRLSIKEREYSNEFGEWVKKSATVCVNVVEEQG..AGDHGADISEMEDVSKAAHKFGRGVEGIFHIGNGYEDLISGLKACN.DLEVDALVVEGGPFNRSDDRLKDFAKAVAVSRILVKGGVVATNGAYEDECRVGLRSGLNVILSGFSGNHHGYMCGYNIKEARRNNFGLPRVLKIMKEE-.AE.KINICIANRELLKVLAKSSRFLNYKgnhMIYPS.MIGDYFMGDAHW.VAVTNSKMYNSPY..FGKTLDSL....EEEL.DCNKVGVLGGRYISWGIADALK--.PEELYVSDVDPWVEHATVKILNDN-GINAYACNGSDKKALESADKSVITTMIPEILIRIKNKF-.DAISLI........
B9AGL1_METSM/1-500             MYDLIKEAIV.DDDAAIELSKM---.......-DKNVVEVVDAISELSLEDTMKLGMKFKRFPLGCDLTEAVVGTCASDLELMELLGNCRLSDMLGLPIHICAYAFADIAEKHGMRGIEVMRKVYDSVDVPLDLDHFGENGPMRLPQNIVGCGGECYNKGPVYTECPRDRIHERLIDKEKAESSDKEEWVKLSSSVAINLTSEQT..GEGHAAPYREAEDIANLAKKYQRGLEAIMFIGDGYDDLITGFEKAI.GIGADVFVLEGGPYNGAKNPVEAFAKAVAASRILCPGKVVGTNGAYERECRIGLRSGLNVIITGFPKNHHGYMCGYEPGTARRGKFGLPRIMQIMKEEV.HN.PNVQVPVLKEDLIPLTTAIKIAGRD...YIYPK.KIGAYTVGDAHW.ATLINSKMYKNLT..LKNDLNDI....VNSV.NGNSVALLGGRFLSWVIANELDKQ.VDEIIISDADPWVQRMTVENLQDALDATIIPGDGDVNSAK-QADSSIISSTVPGISNKILNKVP.NAFNI-v.......
E1RJE5_METP4/1-505             MYDLVKKAVL.DPYAAWELSKM---.......-DKSPAEIVEAVSRLDRDEAMKLGMNFKRFPLGCDLTEILVGTCASDLDKIDILGNSILSDSIGASIHVCAYAFADIAEANGMRGIDLFREVRENTEVPLDLDHFGKFGPMRFPKDITGCWGQCYNEGPPFDGCPRDRIHSRLIDKEEDALGEKDEWIKLSSSVAINLTCIQG..AEGHAAPLDEAIEVAQLGKKYGKGIEAIMFVGDGYEDLIKGFTTAI.DMGVDVFVIEGGPFNLAENRLDAFARAIAMARILVPGKIVVTNGAYEDECRVGLRAGLNGIITGFPKNHHGYMCGYSPGTARRGKFGLPRIIRIIKEEV.QE.DLTKAPIQKDELESLARAVKVVDPV...NVYPR.KIGFAPVGDAHW.VCLPSTPIYERVT..VKRTVHDIrkmaEEGK.IGDSIALLGGRFASWVIAKELEGY.VDQITISDIDPWVEKISVENLQSELKANIYTGNSDDNAAYKNSETAIVCTTIPSISNKISKNLN.DAITLI........
A6URA8_METVS/1-510             MKELIKSSLN.DFDSAMELREIVVKkindkklTESDIIDIVDSVDDLSFEEIQKLGSNFRKFPLGCDLLEIGVGPCSSSLNLSQFIENCILTDAMGYPIHLCTYALADIAEKEGINPIEVMKQVHENVEVPLDIDHFGRFGPMRFPKEITHCMGDCYYNGPPYKGCPRDRIHKRLITKEREHFEEFSDWINLSSTVCVNVVEEQG..GGDHGADISEMENVSKAAQKYGKGIEGIFHIGDGYDDLISGLRACS.ELNVDALVIEGGPFNRSKNKLKDFAKAVAVSRILVKGGVVATNGAYEDECRVGLRSGLNVILSGFSGNHHGYMCGYSPKEARRNNFGLPRVLKIMKEE-.AS.NMGICIANRELLKILVKSSRFLNYNgkhMIYPE.MIGNYFMGDAHW.VSVSNSKMYNAPY..FGKTLDSL....SEEL.DSKKIGVLGARYISWGIASALN--.PEELYVSDVDPLVEYATVKILNDN-GINAYACSGSDRKALEQADKSIITTMIPEIALRIKNKFN.-AISLI........
F6BDV5_METIK/1-506             MRDLIKESVN.NLDAALELRKLIIKklnekklKESDIIEIVDAVDDLSLNEIQKLGSNLRKFPMGCDLVEVAVGPCASSLTLTQFIENCILTDYMGLTIHVCAYALADIGEKEGIPPLEVMKMVYENVDVPLDLDHFGQYGAMRFPKEITHCMGECYYNGPPYKGCPRERIHKRLIDKEKEYAHEFDDWVKLASTVCINVVEEQG..GEEHAAPLEEMAVVAEAAKKYGKGLEGIFHIGDGYDDLITGLKSCI.DFDVDVLVVEGAPFNRAKNRLKAFAKAIAVSRILVKGGVVATNGAYEDECRIGLRSGLNVIISGFSGNHHGYMCGYSPGTAKRGNFGLPRVMRIIKEEI.-K.NMDVNLVSRHDLIAIARSSKFLG-N...IIYPE.TLGGMFIGDAHW.VAIKNSKLHDRVR..IRKTLEDV....ENEY.NGEKLGFLGGRYIAWGIAKKLM--.PEEVYVSDANKWVEEATVKILNEV-GINAYKCNGNDEEVVKNADKTYICSMIPEIILKIKNKV-.DAESLI........
D5VRR8_METIM/1-493             MEDLIKETVK.NKFAGLELRKIILDkiekgklKEEDIIKVVDTVDSLSLEEIIKLGNNLRTFPLGCDLVDLAIGPCSSSLSLIELLENCILSDYIGFPIHICGYAIADIAEKENLTPLEVFKKVYDTVEVPIDIDHFGKYGPMRFPKEIVFCGGDCYNLGLA-RECPRERIHKRLIEKEKEYEEEFLDWIRLASTVCVNVVEEQG..REEHGAPIDEMREVAEAAKRFGKGVEGIFHIGDGYDDLIEGILACI.DLDVDVFVVEGGPFNL-KDRVKNFAKAVAISRILVKGGVVATNGAYEDELRIGLRAGLNTVITGFPLNHHGYMCGYSPGTARRGNFGLRRVMRIIKEE-.--.--GFKLMGKEIAKAIAMSGNFLKGE...-IYPS.RLGSFYIGDAHW.RAIYESKLSN-LK..PSKSIEDI....----.DEEKVGLLGGRYISWKIAER----.AEEAYISDKDEFVERATIRILNEN-NINAYPCNGDDKKAIS-VGKAYITSFIPEIALKLLNKYK.T-----letlf...
Q2FR47_METHJ/1-505             MHDLIRKAIN.DPDAAWELSKI---.......-EKGPRDVIDAVTSLNREEAIKLGNTFKRFPLGCDLTEILVGTCASDLEKTDILGNCMLADSIGASIHVCAYAFADIAEAHGMKGIDLLKEVREITEVPLDLDHFGRYGPMRLPPQIIGCNGQCYNEGPPFSGCPRDRIHSRLLDVEQDALSDRDEWVKISSSVAVNLTCVQG..ADGHAAPLDEAQEVADLARKYGKGIEAIMFVGDGYDDLIKGFTAAL.DMGVDVFVLEGGPFNCSTDRLTAFARAVAIARILVPGKIVATNGAYEDECRIGLRAGLNAIITGFPKNHHGYMCGYSPGKIKRGYFGLPRILQIIKEEV.RD.RWTHTPIQKGELEALARAVKVVGID...TVYPQ.KIRYTYVGDAHW.ACLPHTPVFSRTH..VLKTVQDIvsmaLDGQ.IGDTVALLGGRFVSWAIAKKLDGV.VDSIIISDVDPWIEHVTIDNLRSELHTEISPAKSSDTYAHEHADTSIICSTMPELVRKMSWKCG.DAITLI........
A9A8H1_METM6/1-510             MKELIKNSLN.DLDSAMELRKLVINkinnqklTESDIIEIVDSVDDLSFEDTQKLGSIFRRFPLGCDLLEIGVGPCASSLTLPQFIENCVLTDHMGFPIHLCGYALADIAEKEGLTPIEVMNEVYNNVEVPLDLDHFGRFGPMRFPKEISHCMGDCYYNGPPYKGCPRDRIHKRLTTKEREYSSEFGEWIKKSATVCVNVVEEQG..AGDHGADISEMEDVSKAAHKFGRGVEGIFHIGDGYDDLIAGLKACN.DLEVDALVVEGGPFNRSKDRLKDFAKSVAVSRILVKGGVVATNGAYEDECRVGLRSGLNVILSGFSGNHHGYMCGYNIKEARRNNFGLPRVLKIMKEE-.AE.KINICIANRELLKVLARSSRFLNYKgnhMIYPS.MIGDYFMGDAHW.VAVTNSRMYNTPY..FGKTLDSL....EEEL.NCDKVGVLGGRYISWSIADALK--.PEELYVSDVDPWVEHATVKILNDN-GINAYACNGSDKKALESADKSVITTMIPEIVLRIKNKF-.DAIPI-i.......
#=GC seq_cons                  M+-LIK-AlN.DhDuAhELpKh..........t-pDllElVDAVsDLShE-h.KLGusF++FPLGCDLsElsVGsCASsLsLhplltNClLoDhhGhPIHlCAYAlADIAE+cGhpPlEVM+cVh-sV-VPLDLDHFG+aGPMRFPK-ITtChG-CYhpGPPacGCPR-RIHKRLI-KEKEtusEh--WlKLSSoVsVNlspEQG..uEsHAAPL-Ehc-VAchA+KaGKGlEuIhalGDGYDDLIoGlcAsl.DlsVDVFVlEGGPFNRAKDRLcAFAKAVAsSRILV.GtVVATNGAYEDECRlGLRSGLNsIloGFPtNHHGYMCGYoPGTARRGNFGLPRVh+IhKEEl.ts.slshs.lsK-.LcALApusKFLshp....IYPp.pIGsaalGDAHW.sslpsSslYcplp..lsKTl--l....tpt..ss-KVulLGGRalSWuIAccLc...s-ElhISDsDPWVE+sTV+lLs-s.shssassNGsD+cAhcpADpolIoohIPpIshKIpsKh..-Ahsl.........
//