#=GF ID Flu_NS2
#=GF AC PF00601.23
#=GF DE Influenza non-structural protein (NS2)
#=GF AU Bateman A;0000-0002-6982-4660
#=GF SE Bateman A
#=GF GA 25.90 25.90;
#=GF TC 41.20 104.70;
#=GF NC 24.20 20.70;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -E 1000 -Z 75585367 --cpu 4 HMM pfamseq
#=GF TP Family
#=GF RN [1]
#=GF RM 8113739
#=GF RT An amino acid change in the non-structural NS2 protein of an
#=GF RT influenza A virus mutant is responsible for the generation of
#=GF RT defective interfering (DI) particles by amplifying DI RNAs and
#=GF RT suppressing complementary RNA synthesis.
#=GF RA Odagiri T, Tominaga K, Tobita K, Ohta S;
#=GF RL J Gen Virol 1994;75:43-53.
#=GF DR INTERPRO; IPR000968;
#=GF DR SCOP; 1pd3; fa;
#=GF DR SO; 0100021; polypeptide_conserved_region;
#=GF CC NS2 may play a role in promoting normal replication of the
#=GF CC genomic RNAs by preventing the replication of short-length RNA
#=GF CC species [1].
#=GF SQ 22
#=GS E6XY47_9INFA/28-121 AC E6XY47.1
#=GS A0A2V5KY17_9MICC/13-106 AC A0A2V5KY17.1
#=GS NEP_I66A1/28-121 AC Q3SBF1.1
#=GS D1LNT9_I63A3/28-121 AC D1LNT9.1
#=GS E8Z092_9INFA/28-121 AC E8Z092.1
#=GS NEP_I34A1/28-121 AC P03508.1
#=GS A0A172SNE1_9INFB/30-122 AC A0A172SNE1.1
#=GS Q07FS9_9INFA/28-121 AC Q07FS9.1
#=GS Q0QH15_9INFA/28-121 AC Q0QH15.1
#=GS Q6DP92_9INFA/28-121 AC Q6DP92.1
#=GS NEP_I68A5/28-121 AC Q6XTC3.1
#=GS V5SN66_9INFA/28-121 AC V5SN66.1
#=GS A3DRT9_9INFA/28-121 AC A3DRT9.1
#=GS E4UF20_9INFA/28-121 AC E4UF20.1
#=GS A2V6K7_9INFA/28-121 AC A2V6K7.1
#=GS NEP_INBLE/30-122 AC P03511.1
#=GS NEP_I96A0/28-121 AC Q9Q0L7.1
#=GS A0A8J2Y4I1_9PROT/1-70 AC A0A8J2Y4I1.1
#=GS A0A0B4UVX9_9INFA/28-121 AC A0A0B4UVX9.1
#=GS A0S737_9INFA/28-121 AC A0S737.1
#=GS F2P1E5_I66A1/28-121 AC F2P1E5.1
#=GS G7WV34_9INFA/28-121 AC G7WV34.1
E6XY47_9INFA/28-121 LNGMITQFERLKIYRDSLGESVMRMGDLHSLQNRNATWREELSQKFEEIRWLIAECR------------NILTKTENSF--EQITFLQALQLLLEVESEIRTFSFQLI
A0A2V5KY17_9MICC/13-106 LNGMITQFESLKLYRDSLGEAAMRMGDLHSLQSRNGKWREQLSQKFEEIRWLIEEVR------------HRLKITENSF--EQITFMQALQLLLEVEQEIRTFSFQLI
NEP_I66A1/28-121 LNGMITQFESLKLYRDSLGKAVMRMGDLHSLQNRNGKWREQLSQKFEEIRWLIEEVR------------HRLKVTENSF--EQITFMQALQLLLEVEQEIRTFSFQLI
D1LNT9_I63A3/28-121 LNGMITQFESLKLYRDSLGEAVMRMGDLHSLQSRNGKWREQLSQKFEEIRWLIEEVR------------HRLKITENSF--EQITFMQALQLLLEVEQEIRTFSFQLI
E8Z092_9INFA/28-121 LNGMITQFESLKLYRDSLGEAVMRMGDLHSLQSRNGKWREQLSQKFEEIRWLIEEVR------------HRLKVTENSF--EQITFMQALQLLLEVEQEIRTFSFQLI
NEP_I34A1/28-121 LNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNEKWREQLGQKFEEIRWLIEEVR------------HKLKITENSF--EQITFMQALHLLLEVEQEIRTFSFQLI
A0A172SNE1_9INFB/30-122 MKGIQSQFEQLKLRWESYPNLV-KSTDYH--------------QKRETIRLVTEELYLLSKRIDDNILFHKTVIANSSIIADMVVSLSLLETLYEMKDVVEVYSRQCL
Q07FS9_9INFA/28-121 LNGMITQFEHLKIYRDSLGESVMRMGDLHSLQSRNATWREELSQKFEEIRWLIAECR--------SIL----TKTENSF--EQITFLQALQLLLEVESEIRTFSFQLI
Q0QH15_9INFA/28-121 LNGMITQFESLKLYRDSLEEAVMRMGDLHSLQSRNGKWREQLSQKFEEIRWLIEEVR------------HRLKITENSF--EQITFMQALQLLLEVEQEIRTFSFQLI
Q6DP92_9INFA/28-121 LNGMITQFESLKLYRDSLGETVMRMGDFHSLQIRNGKWREQLSQKFEEIRWLIEEVR------------HRLKITENSF--EQITFMQALQLLLEVEQEIRAFSFQLI
NEP_I68A5/28-121 LNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLGQKFEEIRWLIEEVR------------HRLKITENSF--EQITFMQALQLLFEVEQEIRTFSFQLI
V5SN66_9INFA/28-121 LNGMVTRFEALKIYRDSLGETVMRMGDLHYLQNRNEKWREQLGQKFEEIRWLIEEVR------------HRLIATENSF--EQITFMQALQLLLEVEQEIRTFSFQLI
A3DRT9_9INFA/28-121 LNGMITQFESLKIYRDSLGEAVMRMGDLHLLQNRNGKWREQLGQKFEEIRWLIEEVR------------HRLKTTENSF--EQITFMQALQLLFEVEQEIRTFSFQLI
E4UF20_9INFA/28-121 LNGMITQFESLKLYRDSLGEAVMRMGDLHSLQSRNGKWREQLSQKFEEIRWLIEEVR------------HRLKITENSF--EQITFMQALQLLLEVEQEIRTFSFQLI
A2V6K7_9INFA/28-121 LNGMITQFESLKLYRDSLGEESMRMGDLHSLQNRNVKWREQLSQKFEEIRWLIEEVR------------HRLKITENSF--EQITFMQALQLLLEVEQEIRTFSFQLI
NEP_INBLE/30-122 MKDIQSQFEQLKLRWESYPNLV-KSTDYH--------------QKRETIRLATEELYLLSKRIDDSILFHKTVIANSSIIADMIVSLSLLETLYEMKDVVEVYSRQCL
NEP_I96A0/28-121 LNGMITQFERLKIYRDSLGESMMRMGDLHSLQNRNATWRNELSQKFEEIRWLIAECR------------NILTKTENSF--EQITFLQALQLLLEVESEIRTFSFQLI
A0A8J2Y4I1_9PROT/1-70 ------------------------MGDLHSLQSRNGKWREQLSQKFEEIRWLIEEVR------------HRLKITENSF--EQITFMQALQLLLEVEQEIRTFSFQLI
A0A0B4UVX9_9INFA/28-121 LNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLSQKFEEIRWLIEEVR------------HRLKITENSF--EQITFMQALQLLLEVEQEIRTFSFQLI
A0S737_9INFA/28-121 LSGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLSQKFEEIRWLIEEVR------------HRLKITENSF--EQITFMQALQLLLEVEQEIRTFSFQLI
F2P1E5_I66A1/28-121 LNGMITQFESLKLYRDSLGKAVMRMGDLHSLQNRNGKWREQLSQKFEEIRWLIEEVR------------HRLKVTENSF--EQITFMQALQLLLEVEQEIRTFSFQLI
G7WV34_9INFA/28-121 LNGMITQFESLKLYRDSLGEAVMRMGDLHSLQSRNGKWREQLSQKFEEIRWLIEEVR------------HRLKITENSF--EQITFMQALQLLLEVEQEIRTFSFQLI
#=GC seq_cons LNGMITQFESLKLYRDSLGEuVMRMGDLHSLQsRNGKWREQLSQKFEEIRWLIEEVR............HRLKITENSF..EQITFMQALQLLLEVEQEIRTFSFQLI
//
