GenomeNet

Database: Pfam
Entry: G-7-MTase
LinkDB: G-7-MTase
Original site: G-7-MTase 
#=GF ID   G-7-MTase
#=GF AC   PF12803.5
#=GF DE   mRNA (guanine-7-)methyltransferase (G-7-MTase)
#=GF AU   Coggill P
#=GF SE   Pfam-B_40
#=GF GA   25.00 25.00;
#=GF TC   30.50 341.90;
#=GF NC   24.50 23.30;
#=GF BM   hmmbuild --amino HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   15574411
#=GF RT   Sendai virus RNA-dependent RNA polymerase L protein catalyzes
#=GF RT   cap methylation of virus-specific mRNA.
#=GF RA   Ogino T, Kobayashi M, Iwama M, Mizumoto K;
#=GF RL   J Biol Chem. 2005;280:4429-4435.
#=GF DR   INTERPRO; IPR024352;
#=GF CC   The Sendai virus RNA-dependent RNA polymerase complex, which
#=GF CC   consists of L and P proteins, participates in the synthesis of
#=GF CC   viral mRNAs that possess a methylated cap structure. The
#=GF CC   N-terminal of the L protein acts as the RNA-dependent RNA
#=GF CC   polymerase part of the molecule, family Paramyx_RNA_pol,
#=GF CC   Pfam:PF00946. This domain is the C-terminal part of the L
#=GF CC   protein and it catalyses cap methylation through its mRNA
#=GF CC   (guanine-7-)methyltransferase (G-7-MTase) activity [1].
#=GF SQ   7
#=GS L_NDVB1/1474-1794       AC Q9DLD3.1
#=GS B2BX78_ASPVR/1499-1823  AC B2BX78.1
#=GS L_SENDO/1496-1820       AC O55528.1
#=GS L_MEASC/1494-1804       AC Q9WMB3.1
#=GS Q6YIR9_FDLV8/1489-1801  AC Q6YIR9.1
#=GS L_HENDH/1553-1859       AC O89344.3
#=GS L_MUMPM/1504-1830       AC P30929.1
L_NDVB1/1474-1794                  hr--SYQLYYLRVRGLDNIVLYMGDLYKNMPGILLSNIAATISHPVIHSRLHAVGLVNHDGSHQLADTDFIEMSAKLLVSCTRRVISGL..YSGNKYDLLFPSVLDDNLNEKMLQLISRLCCLYTVLFATTREIPKIRGLTAEEKCSILTEYLLSDAvkpllsPDQ----VSSIMSPNIITFPANLYYMSRKSLNLIREREDRdtILALLFPQ----EPLLEFPSVqdigarvkdpftrqpAAFLQELDLSAP........--ARYDAFTLSQIHPELT..........---.---..---SPNPEEDYLVR....YLFRGIGTASSSWYKASHLLSVPEVRCARHGNSLYLAEGSGAIMSLLELHVPH.
B2BX78_ASPVR/1499-1823             ..QFAYEIYTLGVEGRHLIYDHVFNRLRITSSAVFKVLTNAVSHPRIFKRFWDFGVVKPNRGANLKAQDFKLHALDICMHAVEYFMNQW..DCGTPLEVYLCESDLDVVDERRETFTARHLAFLCSFYGLSSRGPKLQGLDSLQRYSAIRDYLEVQV......TKDHTSRFWQLTGLIIRAVPSTVSYLMQSAVKQFRLRGLG..VPTVLETWNPTFNDLLCDTVE...............AEKDKNMKGTSEyprdywgiEIPRSNIFPCHGLVPSLT..........RDE.EKY..DTSIELPLGPSYLS....HQLRIVGVNSTSCLKALELTSHLSQVANLTGNRLFVGEGAGAMLALYDSVLG-p
L_SENDO/1496-1820                  ..QFAYSLYGLNIRGREEIWGHVVRILKDTSHAVLKVLSNALSHPKIFKRFWNAGVVEPVYGPNLSNQDKTLLALSVCEYSVDLFMHDW..QGGVPLEVFICDNDPDVADMRRSSFLARHLAYLCSLAEISRDGPRLESMNSLERLETLKSYLELTF......LDDPVLRYSQLTGLVIKVFPSTLTYIRKSSIKVLRTRGIG..VPEVLEDWDPEADNALLDGIA...............AEIQQNIPLGHQtrapfwglRVSKSQVLRLRG-YEEIT..........RGEvGRS..GVGLTLPFDGRYLS....HQLRLFGVNSTSCLKALELTYLLSPLVDKDKDRLFLGEGAGAMLSCYDATLG-p
L_MEASC/1494-1804                  ..NWAFDVHYHRPSGKYQMGELLSSFLSRMSKGVFKVLVNALSHPKIYKKFWHCGIIEPIHGPSLDAQNLHTTVCNMVYTCYMTYLDLLlnEELEEFTFLLCESDEDVVPDRFDNIQAKHLCVLADLYCQPGTCPPIRGLRPVEKCAVLTDHIKAEA......RLSPAGSSWNINPIIVDHYSCSLTYLRRGSIKQIRLRVDP.gF-------------------I...............FDALAEVNVSQP........KVGSNNISNMS--IKDFRpp.....hddVAKlLKDinTSKHNLPISGGSLAnyeiHAFRRIGLNSSACYKAVEISTLIRRCLEPGEDGLFLGEGSGSMLITYKEILK-l
Q6YIR9_FDLV8/1489-1801             .r-FAYECYARHIEGKEQYISYVSDKIETMSRSNLSILINSLTHPRVFRKYCDEGVLVPDRGQTLSTQDFRAHSVEYCIASLQRFFEKW..TISGNITILLCDQDEVIIGERELTLKGRIKAMIICIYCLTENSPSLVGLNTKERDEVLTEYLEEVG......QSNIESRYWVLGSIGIKKYNTSLTYIRRSLVKQYRLRDLD..V------------QLLIDEMA...............EQDMESLSMADPi.....fdQVNKTETMGSVSLWQSIKvkdltldrnpRAEsAEYriPTTCEIP------S....QILRIVGVNSTSCSKAHELNSVICTLPLEGKSCLFLAEGSGSMMTYY--MLR-h
L_HENDH/1553-1859                  ..KWAFEIHHRRPHGRHTMVDLLSDLISNTSKHTYKVLSNALSHPRVFKRFVNCGLLLPTQGPYLHQQDFEKLSQNLLITSYMNYLMNW..CDFKKFPFLIAEQDEAVVELREDIITSKHLCMIIDLYANHHKPPWIIDLNPQEKICVLRDFISKCR......HTDVSSRSWNITDLDFMVFYASLTYLRRGIIKQLRIRQ--..VTEVIDTTTMLRDNILVENPPiktgvldirgciiynLEEILSMN----........--TKSTSRKVFNLGSKLS..........V--.---..------------EN....HKYRRIGLNSSSCYKALNLSPLIQRYLPAGSQRLFVGEGSGSMMLLYQQTLG-c
L_MUMPM/1504-1830                  .e-LSYQMYYLRIQGIQGILDYVYMTLRRIPGMAITGISSTISHPRILRRCINLDVIAPINSPHIASLDYTKLSIDAVMWGTKQVLTNI..SQGIDYEIVVPSESQLTLSDRVLNLVARKLSLLAIIWANYNYPPKVKGMSPEDKCQALTTHLLQTVeyvehiQIEKTNIRRMIIEPKLTAYPSNLFYLSRKLLNAIRDSEEGqfLIASYYNSFGYLEPILMESKIfnlsss..esaslteFDFILNLELSEA........SLEKYSLPSLLMTAENMD..........---.---..-----NPFPQPPLH....HVLRPLGLSSTSWYKTISVLNYISHMKISDGAHLYLAEGSGASMSLIETFLP-g
#=GC seq_cons                      ...aAYplYhh+lcG+cphhsalsshlcphSptshplLsNulSHP+Ia+RahshGlltPspGspLssQDapthuhshshtuhppahpph..pputphpllls-pDpslls-Rh.slhuR+Lshlsslas.sppsPplpGLss.E+hpsLp-aLptss......pps.ssphhplsslhlpsasuoLoYlpRu.lKtlRhRt.s..l.t.h.s.....pslLh-s.h...............h-hhtslshup.........pls+sshhshhthhppls..........h..............P.....ls....HhhRhlGlNSoSChKAlcLssllpphh.tstspLFLuEGSGuMhshYcthLs..
//
DBGET integrated database retrieval system