GenomeNet

Database: Pfam
Entry: Gal4_dimer
LinkDB: Gal4_dimer
Original site: Gal4_dimer 
#=GF ID   Gal4_dimer
#=GF AC   PF03902.10
#=GF DE   Gal4-like dimerisation domain
#=GF AU   Finn RD
#=GF SE   DOMO:DM03802;
#=GF GA   21.10 21.10;
#=GF TC   21.20 21.10;
#=GF NC   20.90 20.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11316794
#=GF RT   Recruitment of the transcriptional machinery through GAL11P:
#=GF RT   structure and interactions of the GAL4 dimerization domain. 
#=GF RA   Hidalgo P, Ansari AZ, Schmidt P, Hare B, Simkovich N, Farrell S,
#=GF RA   Shin EJ, Ptashne M, Wagner G; 
#=GF RL   Genes Dev 2001;15:1007-1020.
#=GF DR   INTERPRO; IPR005600;
#=GF DR   SCOP; 1d66; fa;
#=GF SQ   69
#=GS M2SRN4_COCH5/51-93      AC M2SRN4.1
#=GS G8BWF2_TETPH/51-104     AC G8BWF2.1
#=GS E4ZYV7_LEPMJ/155-195    AC E4ZYV7.1
#=GS V2X359_MONRO/61-95      AC V2X359.1
#=GS C4XW80_CLAL4/184-230    AC C4XW80.1
#=GS LAC9_KLULA/134-189      AC P08657.1
#=GS G8YBF8_PICSO/56-101     AC G8YBF8.1
#=GS H6C9N9_EXODN/56-96      AC H6C9N9.1
#=GS C4YKW2_CANAW/63-116     AC C4YKW2.1
#=GS G8YMA3_PICSO/56-101     AC G8YMA3.1
#=GS E7KJ64_YEASA/50-106     AC E7KJ64.1
#=GS C9SKV6_VERA1/55-93      AC C9SKV6.1
#=GS A0A099NUC7_ISSOR/48-88  AC A0A099NUC7.1
#=GS Q4WWQ9_ASPFU/51-93      AC Q4WWQ9.2
#=GS G8YDY4_PICSO/55-128     AC G8YDY4.1
#=GS G8BK22_CANPC/89-143     AC G8BK22.1
#=GS C8VAN3_EMENI/59-100     AC C8VAN3.1
#=GS G3B0V2_CANTC/49-64      AC G3B0V2.1
#=GS S6F0B5_ZYGB2/50-104     AC S6F0B5.1
#=GS G8ZUG5_TORDC/47-95      AC G8ZUG5.1
#=GS B8MMT6_TALSN/51-98      AC B8MMT6.1
#=GS A2QXN4_ASPNC/51-89      AC A2QXN4.1
#=GS J6E9G3_SACK1/50-103     AC J6E9G3.1
#=GS C5M4V0_CANTT/90-139     AC C5M4V0.1
#=GS S0EH55_GIBF5/14-49      AC S0EH55.1
#=GS R0K2A1_SETT2/51-88      AC R0K2A1.1
#=GS A3LV49_PICST/53-121     AC A3LV49.2
#=GS E9F759_METRA/52-90      AC E9F759.2
#=GS G3BD88_CANTC/59-125     AC G3BD88.1
#=GS F9F9Y8_FUSOF/55-89      AC F9F9Y8.1
#=GS W7MWU4_GIBM7/53-92      AC W7MWU4.1
#=GS A1CJE4_ASPCL/73-113     AC A1CJE4.1
#=GS G7XFS3_ASPKW/51-89      AC G7XFS3.1
#=GS H2AWF0_KAZAF/44-111     AC H2AWF0.1
#=GS A5DY92_LODEL/161-231    AC A5DY92.1
#=GS B6QT91_PENMQ/51-107     AC B6QT91.1
#=GS G3YBG9_ASPNA/18-56      AC G3YBG9.1
#=GS Q2U4J0_ASPOR/45-77      AC Q2U4J0.1
#=GS Q755I3_ASHGO/48-102     AC Q755I3.1
#=GS Q6BMQ9_DEBHA/61-120     AC Q6BMQ9.2
#=GS B6HF60_PENCW/51-88      AC B6HF60.1
#=GS K0KTZ9_WICCF/22-63      AC K0KTZ9.1
#=GS E7M166_YEASV/50-106     AC E7M166.1
#=GS V2XHR3_MONRO/72-108     AC V2XHR3.1
#=GS W7MM59_GIBM7/22-62      AC W7MM59.1
#=GS Q5A5R1_CANAL/63-116     AC Q5A5R1.1
#=GS I2H6X1_TETBL/57-108     AC I2H6X1.1
#=GS C5E4R9_ZYGRC/50-101     AC C5E4R9.1
#=GS N1RBX6_FUSC4/4-38       AC N1RBX6.1
#=GS G0WCD0_NAUDC/51-117     AC G0WCD0.1
#=GS J8PVU2_SACAR/50-105     AC J8PVU2.1
#=GS M3K2C0_CANMX/67-129     AC M3K2C0.1
#=GS C4QZ96_PICPG/83-120     AC C4QZ96.1
#=GS Q6BUE8_DEBHA/53-125     AC Q6BUE8.2
#=GS G8YMR4_PICSO/55-130     AC G8YMR4.1
#=GS G0WFT2_NAUDC/50-89      AC G0WFT2.1
#=GS G0VHW3_NAUCC/52-134     AC G0VHW3.1
#=GS C5E274_LACTC/50-102     AC C5E274.1
#=GS H6BP98_EXODN/41-79      AC H6BP98.1
#=GS L2G392_COLGN/18-54      AC L2G392.1
#=GS D2R5Z6_PIRSD/44-86      AC D2R5Z6.1
#=GS GAL4_YEAST/50-106       AC P04386.2
#=GS GAL4_YEAST/50-106       DR PDB; 1HBW B; 50-106;
#=GS GAL4_YEAST/50-106       DR PDB; 1D66 A; 50-64;
#=GS GAL4_YEAST/50-106       DR PDB; 3COQ A; 50-96;
#=GS GAL4_YEAST/50-106       DR PDB; 1HBW A; 50-106;
#=GS GAL4_YEAST/50-106       DR PDB; 1D66 B; 50-64;
#=GS GAL4_YEAST/50-106       DR PDB; 3COQ B; 50-96;
#=GS V2YZJ5_MONRO/97-129     AC V2YZJ5.1
#=GS N4TUC2_FUSC1/4-38       AC N4TUC2.1
#=GS S7ZDY5_PENO1/51-91      AC S7ZDY5.1
#=GS M2SRU6_COCSN/59-102     AC M2SRU6.1
#=GS A0A0C4DJ93_FUSO4/4-39   AC A0A0C4DJ93.1
#=GS G2XAH8_VERDV/55-90      AC G2XAH8.1
#=GS G0VEK9_NAUCC/59-111     AC G0VEK9.1
M2SRN4_COCH5/51-93                 .....TRAYLTSVEKRLHSLEALVAQLVPGa.................vpNDVD--------..---.-----..----------gfnwkeedlni......................
G8BWF2_TETPH/51-104                .....TRAHLTEVEDRLSKFEQLFYEFFPN....................INLDNTLNLNNA..TEM.KKILL..----------dnsvdfikd........................
E4ZYV7_LEPMJ/155-195               .....TRAYLTGVEKRLHDVEALVTQLLPG....................VSIDEVLAS---..---.-----..----------periqna..........................
V2X359_MONRO/61-95                 ....k--AYVEGLENRVEKMEQLIREFLPD....................EDLARELGN---..---.-----..----------ft...............................
C4XW80_CLAL4/184-230               .....TRAHLTEVETRLTRVTQMLRFLLPP...................gVDVDKLMES---..---.-----..----------grfegalrpfre.....................
LAC9_KLULA/134-189                 .....TRAHLTEMENRVAELEQFLKELFPV....................WDIDRLLQQKDT..YRI.RELLT.mGSTNTVPGLA.................................
G8YBF8_PICSO/56-101                .....TRAHLTEVEAKVRGLENIVSFLLARdl................ssNQIDGLLRQE--..---.-----..----------rykevls..........................
H6C9N9_EXODN/56-96                 .....TRKHLTEVEERLEKAEALLRTVFTE....................AQLAEMLA----..---.-----..----------hgasagtn.........................
C4YKW2_CANAW/63-116                .....TRAHLTEVENRVSQLEGILHYLLPD....................HDIDEIINDHDK..AIL.APIRQ..-KLQPSPKPC.................................
G8YMA3_PICSO/56-101                .....TRAHLTEVEAKVRGLENMVSFLLARdl................ssNQIDGLLRQE--..---.-----..----------rykevls..........................
E7KJ64_YEASA/50-106                .....TRAHLTEVESRLERLEQLFLLIFPR....................EDLDMILKMDSL..QDI.KALLTglFVQDNVNKDA.................................
C9SKV6_VERA1/55-93                 .....TRVYLTDVESRLERVEKLFAELLPD....................VDINKALG----..---.-----..----------aratgt...........................
A0A099NUC7_ISSOR/48-88             .....TRSHLTQVENELQQIQNVLQYLIPDk.................slEDIIKIVQH---..---.-----..----------aqss.............................
Q4WWQ9_ASPFU/51-93                 .....TRQHLTYVEERLQAFETALGRLFPG....................GDLDATV-----..---.-----..----------rsllhdqdtpq......................
G8YDY4_PICSO/55-128                .....TRTHLTKVEGRVNSLERLLKKILPEdveind.......llrtmeaSDK---------..---.-----..----------tpildnsyndnstdkqfykqvslttndfksvpv
G8BK22_CANPC/89-143                .....TRAHLTDVETKLSKMEDIFHHLLPN....................YDLDDILNNFGNfeEKL.KPV--..----------kdklseagkd.......................
C8VAN3_EMENI/59-100                .....TRQHLTYVEDRLQAFESALGRLFPG....................GDLDATV-----..---.-----..----------rsllqdqdpl.......................
G3B0V2_CANTC/49-64                 .....TRNHLTKVENRVQKLE---------....................------------..---.-----..----------.................................
S6F0B5_ZYGB2/50-104                .....TRAHLTKVESKLDALEQLFHELLPD....................EDLNMFLNKGFT..PQT.KERL-..----------kkslngklqra......................
G8ZUG5_TORDC/47-95                 .....TRVHLTEVESRLEYLEQLLTELFPG....................VDLDEIYKCES-..---.-----..----------ydkannligrlll....................
B8MMT6_TALSN/51-98                 .....TRQHLTYVEDRLSAVETALSKLFPG....................GDLDSVV-----..---.-----..----------ssllqdqdphsrksvs.................
A2QXN4_ASPNC/51-89                 .....TRQHLTYVEERLQAFETALSRLFPG....................GDLDATV-----..---.-----..----------rsllhdq..........................
J6E9G3_SACK1/50-103                .....TRAHLTEVESRLEKLEDLFLLMFPR....................ENLDSILNMDSL..DEV.KVMLK..----------qlymqdygd........................
C5M4V0_CANTT/90-139                .....TRAHLTEVENRVAQLESILNYLLPP...................nTDIDDLIKNKTL..--L.EPI--..----------kqnitkla.........................
S0EH55_GIBF5/14-49                 ....y---YLTRVERRLANVERLFHQLLPD....................VDVNEAL-----..---.-----..----------vsrgve...........................
R0K2A1_SETT2/51-88                 .....TRAYLTSVEKRLHTLESVVTQLVPG....................VDIEEILA----..---.-----..----------spnvp............................
A3LV49_PICST/53-121                .....TRTHLSKVEDRVKALEKLLVRLLPGdveindl......lrasesnSDIKEEVETIDN..PQFyKQISL..----------ttedlsnip........................
E9F759_METRA/52-90                 .....TRQYLTSVERRLNYLEKLVAQKLPD....................LDVDEALAAI--..---.-----..----------atss.............................
G3BD88_CANTC/59-125                .....TRAYLTQVESRATTLEKILRRMLPEdvevqd.......llriaenEDDDNELENIHN..NFF.KQINL..T---------skelskap.........................
F9F9Y8_FUSOF/55-89                 ....s---YLTRVERRLANVERLFGQLLPD....................VDINEALA----..---.-----..----------sqgv.............................
W7MWU4_GIBM7/53-92                 .....TRDYLTRVERRLANVERLFHQLLPD....................VDINEALASRD-..---.-----..----------vevp.............................
A1CJE4_ASPCL/73-113                .....TRQHLTFVEERLQAFETALGRLFPG....................GDLDATV-----..---.-----..----------rsllqdqdv........................
G7XFS3_ASPKW/51-89                 .....TRQHLTYVEERLQAFETALSRLFPG....................GDLDATV-----..---.-----..----------rsllhdq..........................
H2AWF0_KAZAF/44-111                .....TRAHLTEVEKKLNNLTILFGKLFPGenignlvk....rfnidsskS-----------..---.-----..----------dfdnayltnneeddkkinkanvtipi.......
A5DY92_LODEL/161-231               .....TRAHLTEVENKLQKLEDLLAYILPSdyfaald......eivgegeE-----------..---.-----..----------dlnfevewkpvrdqlkglkknyevklkqnkt..
B6QT91_PENMQ/51-107                .....TRQHLTYVEDRLNAVETALSKLFPG....................GDLDNVVS----..---.-----..----------sllqdqdphqrkslspsvsskesp.........
G3YBG9_ASPNA/18-56                 .....TRQHLTYVEERLQAFETALSRLFPG....................GDLDATV-----..---.-----..----------rsllhdq..........................
Q2U4J0_ASPOR/45-77                 .....TRQHLTYVEDRLQAFETALGRLFPG....................GDLDA-------..---.-----..----------tad..............................
Q755I3_ASHGO/48-102                .....TRAHLTEVETRLGQMEQLLRNAFVD....................LDADTLLKHRHD..PQL.REILF..GRTVDIGALS.................................
Q6BMQ9_DEBHA/61-120                .....TRAHLTQVENKVKSLENLITYLLPQev................nsRGIDQLLYQN--..---.-----..----------tfkdvlrpykdmlqngstsde............
B6HF60_PENCW/51-88                 .....TRQHLTYVEDRLHSFETALGRLFPG....................GDLDATLR----..---.-----..----------sllqn............................
K0KTZ9_WICCF/22-63                 .....TRVHLTKVENRVRDLENLVHELLPD....................ADVDKLLSR---..---.-----..----------qvpksvtp.........................
E7M166_YEASV/50-106                .....TRAHLTEVESRLERLEQLFLLIFPR....................EDLDMILKMDSL..QDI.KALLTxlFVQDNVNKDA.................................
V2XHR3_MONRO/72-108                gyveg-------LENRLEKMEQLLKKLLPG....................VDISNELDNDS-..---.-----..----------pea..............................
W7MM59_GIBM7/22-62                 .....TRDYLTRVERRLANVERLFHQLLPD....................VDINEALASRD-..---.-----..----------vevpa............................
Q5A5R1_CANAL/63-116                .....TRAHLTEVENRVSQLEGILHYLLPD....................HDIDEIINDHDK..AIL.APIRQ..-KLQPSPKPC.................................
I2H6X1_TETBL/57-108                .....TRNHLTKVENRLSILELLFREIFPQ....................TDIEKILKLDSI..SKM.SDLLK..----------rsvriql..........................
C5E4R9_ZYGRC/50-101                .....TRAHMTKVETKLDRLEQLFRELFPE....................EDLDKVLNDRNT..GQL.KERL-..----------krflvrra.........................
N1RBX6_FUSC4/4-38                  ....f---YLTRVERRLANVERLFGQLLPD....................VDINEALA----..---.-----..----------sqgv.............................
G0WCD0_NAUDC/51-117                .....TRAHLTRVEDKLSKLENLFNALFIGkestptnt....rsmngynvDDIDDTEHTDSS..EIL.NSILK..----------letpae...........................
J8PVU2_SACAR/50-105                .....TRAHLTEVELRLEKLEDLFLLMFPL....................ENLNNVLKIESL..HDV.KVMLI..----------rslkqelaavn......................
M3K2C0_CANMX/67-129                .....TRAHLTDVENRVGQLEEILHYLLPN....................HQIDDILNDHDK..KLL.RPIRQ..----------klyhdendddnhsndsnn...............
C4QZ96_PICPG/83-120                .....TRAHLTKVENRVRMLEDLLERVFPT....................QSVDQLLEKR--..---.-----..----------tsl..............................
Q6BUE8_DEBHA/53-125                .....TRAYLTRVEKRVKGLESLLKRLLPEdveinellrtieinkshsidGDSGGGVDDVSQ..QFY.KQIN-..----------ltsnelsei........................
G8YMR4_PICSO/55-130                .....TRTHLTKVEGRVSSLERLLKKILPEdveindllr..tmeasdktpI-----------..---.-----..----------lndniyndnntdkqfykqvslttndfksvpvt.
G0WFT2_NAUDC/50-89                 .....TRVHLTNLENKLEKLENLFNKLLPN....................ENINEILQKFDS..N--.-----..----------dd...............................
G0VHW3_NAUCC/52-134                .....TRAHLTKVEDRLTKLEFLFNELFTKremdgdaky.svnksikegeDDEDENDNDNDN..DLL.DQILK..----------mesidemrsalqgvisplt..............
C5E274_LACTC/50-102                .....TRAHLTEVENRLHQLERLFGTLFPG....................YDWKDTSKDPSL..SKL.RHMLK..----------nqkdqyer.........................
H6BP98_EXODN/41-79                 ....s---YLTSVERRLQKLETLFAQMHPD....................VDLESALGS---..---.-----..----------ssvpple..........................
L2G392_COLGN/18-54                 ....s---YLTSVESRLASLEHVFKQMLPD....................VDIDRALSADSR..---.-----..----------rr...............................
D2R5Z6_PIRSD/44-86                 ....w--AYLTEMESKGEELEQILSN----....................------------..---.-----..----------wdspsfvelakradtildeldri..........
GAL4_YEAST/50-106                  .....TRAHLTEVESRLERLEQLFLLIFPR....................EDLDMILKMDSL..QDI.KALLTglFVQDNVNKDA.................................
#=GR GAL4_YEAST/50-106       SS    .....HHHHHHHHHHHHHHCCCSSSSHHHH....................XXSSXXXXXXXX..XXX.XXXXXXXXXXXXXXXXX.................................
V2YZJ5_MONRO/97-129                ....k--AYITALEDRLESLEGLLKRLRPD....................HDFTSEL-----..---.-----..----------gp...............................
N4TUC2_FUSC1/4-38                  ....f---YLTRVERRLANVERLFGQLLPD....................VDINEALA----..---.-----..----------sqgv.............................
S7ZDY5_PENO1/51-91                 .....TRQHLTYVEDRLHAFETALSRLFPG....................GDLDATLR----..---.-----..----------sllqnpei.........................
M2SRU6_COCSN/59-102                .....TRAYLTSVEKRLHSLEALVAQLVPG....................VDIEELLSS---..---.-----..----------pnatiptpqi.......................
A0A0C4DJ93_FUSO4/4-39              ....f---YLTRVERRLANVERLFGQLLPD....................VDINEALA----..---.-----..----------sqgve............................
G2XAH8_VERDV/55-90                 .....TRVYLTDVESRLERVEKLFAELLPD....................VDIDQAL-----..---.-----..----------garv.............................
G0VEK9_NAUCC/59-111                .....TRVHLTQTENKLEKLERLFIELFPD....................ENVENLIHVMDS..KDV.MKLRD..----------lklkmaqi.........................
#=GC SS_cons                       .....HHHHHHHHHHHHHHCCCSSSSHHHH....................XXSSXXXXXXXX..XXX.XXXXXXXXXXXXXXXXX.................................
#=GC seq_cons                      .....TRsHLTcVEsRLpplEpLhppLhPs....................tDl-phlt...........................tp...............................
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