GenomeNet

Database: Pfam
Entry: Gemini_AL1
LinkDB: Gemini_AL1
Original site: Gemini_AL1 
#=GF ID   Gemini_AL1
#=GF AC   PF00799.18
#=GF DE   Geminivirus Rep catalytic domain
#=GF PI   Geminivirus_AL1;
#=GF AU   Bateman A
#=GF SE   Pfam-B_286 (release 2.1)
#=GF GA   21.10 21.10;
#=GF TC   21.10 21.30;
#=GF NC   21.00 20.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   12130667
#=GF RT   The structure of a replication initiator unites diverse aspects
#=GF RT   of nucleic acid metabolism. 
#=GF RA   Campos-Olivas R, Louis JM, Clerot D, Gronenborn B, Gronenborn
#=GF RA   AM; 
#=GF RL   Proc Natl Acad Sci U S A 2002;99:10310-10315.
#=GF DR   INTERPRO; IPR022690;
#=GF DR   SCOP; 1l2m; fa;
#=GF CC   The AL1 proteins encodes the replication initiator protein (Rep)
#=GF CC   of geminiviruses, which is a replicon-specific initiator enzyme
#=GF CC   and is an essential component of the replisome [1]. For
#=GF CC   geminivirus Rep protein, this N-terminal region is crucial for
#=GF CC   origin recognition and DNA cleavage and nucleotidyl transfer
#=GF CC   [1].
#=GF SQ   22
#=GS REPA_MSVS/10-117         AC P14990.1
#=GS A2QYZ7_ASPNC/35-149      AC A2QYZ7.1
#=GS F8PXP0_SERL3/56-159      AC F8PXP0.1
#=GS U9TNC2_RHIID/1-84        AC U9TNC2.1
#=GS REP_BCTVC/7-119          AC P14991.2
#=GS L7FL16_ENTIV/41-97       AC L7FL16.1
#=GS REP_TYLCI/5-117          AC P27259.1
#=GS A0A0M9E761_9DELT/4-111   AC A0A0M9E761.1
#=GS REP_TPCTV/8-120          AC Q88888.1
#=GS B1P3D8_BCTIV/18-133      AC B1P3D8.1
#=GS U9TRZ4_RHIID/23-135      AC U9TRZ4.1
#=GS L7FKJ3_ENTIV/30-142      AC L7FKJ3.1
#=GS REPE_ONYPE/11-144        AC P60470.1
#=GS REP_MSVS/10-117          AC P14989.2
#=GS D8WZ30_TCTVB/8-120       AC D8WZ30.1
#=GS F8Q706_SERL3/97-200      AC F8Q706.1
#=GS C3UV60_ECSVG/8-116       AC C3UV60.1
#=GS A0A0A2I3L7_PENEN/41-109  AC A0A0A2I3L7.1
#=GS REP_BGYMJ/7-119          AC P0CK40.1
#=GS L7FL16_ENTIV/92-138      AC L7FL16.1
#=GS X6MQ48_RETFI/202-306     AC X6MQ48.1
#=GS L7FMK9_ENTIV/38-151      AC L7FMK9.1
REPA_MSVS/10-117                    .........FSHRNANTFLTYPKCP.E.NPEI.ACQMI.....-WELVVRW..IPKYIL...CAREAHK......D.GSLHLHALLQTEKPVRIS.DSRFFDING-----.............-FHPNIQ.....SAKSVNRVRDYILKE.PLA.VfERGTFI--pr............................................
#=GR REPA_MSVS/10-117         AS    .................................................................................................................................................*.................................................................
A2QYZ7_ASPNC/35-149                 .......kk--IHRRWIFLTYTECP.L.EHEVdFVEGL.....RAMLKQNSlaSDRFYG...CCQEY-T......Q.KGIVYHVLLHLGKQVNWK.A-------------.............-------.....---------------.---.-.--------sharrvllvsnsphesiniltprpgqvgnfieshvkycekvandnc
F8PXP0_SERL3/56-159                 .........FRWSARNMLLTYSQIG.D.RPNQ.ALSDV.....IAQLSLQL..AE--WA...AIREHHQ......D.GGSHWHVIVKFDVPIRSR.NPAFFDVDG-----.............-IHPNVKt..laSAKSVCNAWTYLQKE.E--.-.--------gadhfg........................................
#=GR F8PXP0_SERL3/56-159      pAS   .................................................................................................................................................*.................................................................
U9TNC2_RHIID/1-84                   ......mpg----------------.-.---R.IIELL.....RFKLDNRR..NAIVISgfsAGREAHQ......E.GGFHTHILMKFEKKINVN.DANFMDVEDED---.............-------.....---------------.---.-.--------wsiipilrrykilklceervs.........................
REP_BCTVC/7-119                     .........FRIQAKNIFLTYPQCS.L.SKEE.ALEQI.....-QGIQLSS..NKKYIK...IARELHE......D.GQPHLHVLLQLEGKVQIT.NIRLFDLVSPTRSA.............HFHPNIQ.....GAKSSSDVKSYVDKD.GDT.I.EWGEFQID..............................................
#=GR REP_BCTVC/7-119          AS    .................................................................................................................................................*.................................................................
L7FL16_ENTIV/41-97                  .........FRIDAKNLFLTYPQCD.I.YKVI.ALKQV.....-KGALFNR..GVKYIL...VCKEDHH......E.ND----------------.--------------.............-------.....---------------.---.-.--------erklpkyw......................................
REP_TYLCI/5-117                     .........FKIYAKNYFLTYPNCS.L.SKEE.ALSQL.....-KKLETPT..NKKYIK...VCKELHE......N.GEPHLHVLIQFEGKYQCK.NQRFFDLVSPNRSA.............HFHPNIQ.....AAKSSTDVKTYVEKD.GNF.I.DFGV----sqid..........................................
#=GR REP_TYLCI/5-117          AS    .................................................................................................................................................*.................................................................
A0A0M9E761_9DELT/4-111              .....rnpv-----KQLFITFPHSV.C.DKCK.FRDDL.....---L--RF..EPDYYK...VCEEKHK......D.GTPHLHAVVRFKNKYSKAfVLRHFKEIY--PDD.............YKRIDVK.....PVRSIKKSIQYLSKE.DPFpL.ESGTFS--ds............................................
#=GR A0A0M9E761_9DELT/4-111   pAS   .................................................................................................................................................*.................................................................
REP_TPCTV/8-120                     .........FQIAAKNYFLTYPNCS.L.SKEE.ALDQL.....-QRLQTPT..NKKYIK...VARELHE......N.GEPHLHVLIQFEGKFNCK.NQRFFDLVSPTRST.............HFHPNIQ.....GAKSSSDVNSYVDKD.GDT.I.EWGEFQID..............................................
#=GR REP_TPCTV/8-120          AS    .................................................................................................................................................*.................................................................
B1P3D8_BCTIV/18-133                 ........l-RFQKKNAFLTYSQIGgD.FKDY.IFEKL.....-KTLLESY..VILSLA...VSLEHHQpteeqpE.GGFHTHCIIQCDKKLDVN.GNLFFNIILPDGRT.............-IHPRID.....GLNAPKRAFEYITKE.D--.-.--------tsprtfge......................................
#=GR B1P3D8_BCTIV/18-133      pAS   .................................................................................................................................................*.................................................................
U9TRZ4_RHIID/23-135                 .........FSIIAKIIFFTYSRCP.L.TPSY.CIESL.....RSKLSSRR..SPIGIIgysVGLEHLT......D.GGLHIHVLIKLDKKIDLR.DGRFFDIVDGDGET.............VYHPSVE.....ECKNFNAARDYIRKE.---.-.YKENL---dag...........................................
#=GR U9TRZ4_RHIID/23-135      pAS   .................................................................................................................................................*.................................................................
L7FKJ3_ENTIV/30-142                 .........FRLNAKNLLLTWPQTP.L.PKEN.AMKQL.....-RTLLDDY..GIIYIV...VCQEKHE......K.EGLHLHAVVMLERKVCFR.DQSCLNLSSDWISK.............DIHGNYL.....SAKSPKDAVAYVKKE.T--.-.--------teelisgeklt...................................
#=GR L7FKJ3_ENTIV/30-142      pAS   .................................................................................................................................................*.................................................................
REPE_ONYPE/11-144                   .......tm--FQAQNIFLTYSQCD.L.SKEE.IKTFIinlcnEKKLQIN-..---YLI...IGIENHQ......DhKGKHHHVFFQLNKQFRTR.DLTIFNIPKNIKEKklidhenikikdfFYSPHIEprpgnPIKDTTDVRNYVKKD.GDF.I.EEGTFK--hv............................................
#=GR REPE_ONYPE/11-144        AS    .................................................................................................................................................*.................................................................
REP_MSVS/10-117                     .........FSHRNANTFLTYPKCP.E.NPEI.ACQMI.....-WELVVRW..IPKYIL...CAREAHK......D.GSLHLHALLQTEKPVRIS.DSRFFDING-----.............-FHPNIQ.....SAKSVNRVRDYILKE.PLA.VfERGTFI--pr............................................
#=GR REP_MSVS/10-117          AS    .................................................................................................................................................*.................................................................
D8WZ30_TCTVB/8-120                  .........YRIHAKNIFLTYPHCH.L.TKED.ALLQL.....-QTIQCPS..TKKFIR...ICRERHD......N.GEPHLHVLIQFEGKIQLY.NPRHFDLRDGGSGR.............ICHPNIQ.....GAKSSSDVKSYIEKD.GDY.I.DWGEFQID..............................................
#=GR D8WZ30_TCTVB/8-120       pAS   .................................................................................................................................................*.................................................................
F8Q706_SERL3/97-200                 .........FRWSARNMLLTYSQIG.D.RPNQ.ALSDA.....IARLSPQ-..-PAEWA...AVREHHQ......D.GGSHWHVIVKFDVPIRSR.NPAFFDVDG-----.............-IHPNVKm..laSAKSVRDAWTYLQKE.E--.-.--------gadhfg........................................
#=GR F8Q706_SERL3/97-200      pAS   .................................................................................................................................................*.................................................................
C3UV60_ECSVG/8-116                  .........FRIQGKAFFLTYSQCP.R.EPKD.VGEFL.....TSHSTLAS..HVVYVR...VQQEKHQ......D.GNNHLHAIVCTSERRDIR.DPRIFDFGE-----.............-FHPKIE.....TCRSVSKSLKYIQKEaGSF.Y.EHGT----vpcd..........................................
#=GR C3UV60_ECSVG/8-116       pAS   .................................................................................................................................................*.................................................................
A0A0A2I3L7_PENEN/41-109             ......rfr----HRWVFLTYARCS.LeSKDD.FEEGF.....SDMLNRNG..FRQATY..yGCREHHK......F.EGIHYHVLVNLGKQ----.--------------.............-------.....---------------.---.-.--------pnwsyd........................................
REP_BGYMJ/7-119                     .........FRVQSKNYFLTYPRCT.I.PKEE.ALSQL.....-QKIHTTT..NKKFIK...VCEERHD......N.GEPHLHALIQFEGKFICT.NKRLFDLVSTTRSA.............HFHPNIQ.....GAKSSSDVKEYIDKD.GVT.I.EWGQFQVD..............................................
#=GR REP_BGYMJ/7-119          AS    .................................................................................................................................................*.................................................................
L7FL16_ENTIV/92-138                 klpkywgis----------------.-.----.-----.....--------..------...-------......-.------------------.----------SRRK.............KYHGHYE.....KVDSSVNVMKYVKKD.GDW.I.EEGT----apve..........................................
#=GR L7FL16_ENTIV/92-138      pAS   .................................................................................................................................................*.................................................................
X6MQ48_RETFI/202-306                .........FRLQAKNLFLTYPQCT.L.QPEE.ALAIL.....ETKLQIN-..--EY-L...IAVENHI......Q.KGRHLHCYINCKKKVDIR.SAHRLDLDG-----.............-FHGNYQ.....GCRSLTAVKKYCTKE.KNY.I.T-------niynfait......................................
#=GR X6MQ48_RETFI/202-306     pAS   .................................................................................................................................................*.................................................................
L7FMK9_ENTIV/38-151                 .........FRLNAKNLFCTWPQTA.L.PKEN.AFKQL.....KTILGVY-..GIKYLL...VCQERHE......E.EGLHLHAVAILDKKVNFK.DCRCLDLSTDWISR.............DIHGQYQ.....AARAIRDAIAYCKKK.DNW.L.EEGE----spaiq.........................................
#=GR L7FMK9_ENTIV/38-151      pAS   .................................................................................................................................................*.................................................................
#=GC seq_cons                       .........Fphpu+NhFLTYspCs.h.p.-p.shptl......ppLphp...t.talh...lspEpHp......c.Gs.HhHsllph-tphphp.s.phFDlss...................hHsplp.....ss+SspcshpYlpK-.s.............s.............................................
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