GenomeNet

Database: Pfam
Entry: Glyco_hydro_70
LinkDB: Glyco_hydro_70
Original site: Glyco_hydro_70 
#=GF ID   Glyco_hydro_70
#=GF AC   PF02324.13
#=GF DE   Glycosyl hydrolase family 70
#=GF PI   Gluco_S_transf; 
#=GF AU   Bashton M, Bateman A
#=GF SE   Pfam-B_965 (release 5.2)
#=GF GA   18.90 18.90;
#=GF TC   18.90 18.90;
#=GF NC   18.80 18.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF WK   Glycoside_hydrolase_family_70
#=GF RN   [1]
#=GF RM   1747104
#=GF RT   A classification of glycosyl hydrolases based on amino acid
#=GF RT   sequence similarities. 
#=GF RA   Henrissat B; 
#=GF RL   Biochem J 1991;280:309-316.
#=GF RN   [2]
#=GF RM   8982063
#=GF RT   Cloning and sequencing of a gene coding for a novel
#=GF RT   dextransucrase from Leuconostoc mesenteroides NRRL B-1299
#=GF RT   synthesizing only alpha (1-6) and alpha (1-3) linkages. 
#=GF RA   Monchois V, Willemot RM, Remaud-Simeon M, Croux C, Monsan P; 
#=GF RL   Gene 1996;182:23-32.
#=GF DR   INTERPRO; IPR003318;
#=GF DR   CAZY; GH70;
#=GF CC   Members of this family belong to glycosyl hydrolase family 70
#=GF CC   [1] Glucosyltransferases or sucrose 6-glycosyl transferases
#=GF CC   (GTF-S) catalyse the transfer of D-glucopyramnosyl units from
#=GF CC   sucrose  onto acceptor molecules [2], EC:2.4.1.5.  This family
#=GF CC   roughly corresponds to the N-terminal catalytic domain of the
#=GF CC   enzyme. Members of this family also contain the Putative cell
#=GF CC   wall binding domain Pfam:PF01473, which corresponds with the
#=GF CC   C-terminal glucan-binding domain.
#=GF SQ   31
#=GS B1N008_LEUCK/453-1313      AC B1N008.1
#=GS U2KBZ8_9STRE/260-1062      AC U2KBZ8.1
#=GS G5KCZ1_9STRE/11-829        AC G5KCZ1.1
#=GS GTFB_STRMU/269-1074        AC P08987.3
#=GS A0A0D1LM29_9LACT/388-1183  AC A0A0D1LM29.1
#=GS Q03XV7_LEUMM/344-1142      AC Q03XV7.1
#=GS Q03XV7_LEUMM/2023-2821     AC Q03XV7.1
#=GS Q04GD2_OENOB/292-1115      AC Q04GD2.1
#=GS GTFC_STRMU/295-1103        AC P13470.2
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIE G; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIB D; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIC E; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIC C; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIC G; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIB H; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIC D; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIB G; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIE H; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIE B; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIC F; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIB F; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIE D; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIE A; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIE F; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIB B; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIE E; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIB C; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIE C; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIC H; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIC B; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIB A; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIC A; 295-1087;
#=GS GTFC_STRMU/295-1103        DR PDB; 3AIB E; 295-1087;
#=GS A8AVK3_STRGC/334-1148      AC A8AVK3.1
#=GS B1YMN6_EXIS2/16-200        AC B1YMN6.1
#=GS A0A062XMN8_LEUPS/328-546   AC A0A062XMN8.1
#=GS A5VL73_LACRD/551-1359      AC A5VL73.1
#=GS Q2UIS6_ASPOR/324-482       AC Q2UIS6.1
#=GS U2KIM5_9STRE/272-1095      AC U2KIM5.1
#=GS GTFD_STRMU/281-1103        AC P49331.3
#=GS B1MZT6_LEUCK/1-112         AC B1MZT6.1
#=GS U2KIP9_9STRE/1-53          AC U2KIP9.1
#=GS U2J7Y6_9STRE/274-1078      AC U2J7Y6.1
#=GS B1YMN6_EXIS2/334-766       AC B1YMN6.1
#=GS U2J3Q1_9STRE/258-1001      AC U2J3Q1.1
#=GS B1MZT6_LEUCK/994-1791      AC B1MZT6.1
#=GS U2IKC9_9STRE/263-1069      AC U2IKC9.1
#=GS Q03VD3_LEUMM/352-1171      AC Q03VD3.1
#=GS G9WG05_9LACT/281-1082      AC G9WG05.1
#=GS A0A062XKC4_LEUPS/1-568     AC A0A062XKC4.1
#=GS B1N0B6_LEUCK/312-1112      AC B1N0B6.1
#=GS B1MWP4_LEUCK/349-1147      AC B1MWP4.1
#=GS T0TFB4_9STRE/282-1087      AC T0TFB4.1
#=GS B1MZT7_LEUCK/361-1027      AC B1MZT7.1
#=GS Q03VD8_LEUMM/370-1169      AC Q03VD8.1
B1N008_LEUCK/453-1313                 ...................................................LLMTWWPDKQTQANYLNFMSSKGL.G.IT.........TT.YTAATSQKTLNDAAFVIQTAIEQQISLKKSTEWLRDAI.......DSFVTTQANWNKQTED..........EAFDglqWLQGGFLAYQD.dSH.....RTPNTDSgNNRKLGRQPVNIDGSKDTT---..-D..GKGSEFLLANDIDNSNPIVQAEQLNWLHYLMNFGSITGNNDNANFDGIRVDAVDNVDADLLKIAGDYFKALYGTDKSDANANKHLSILEDWNGKDPQYVNQQGNAQLTMDYTVTSQFGNSLTHgannrsnmwyfldtgyylngdINKKIV.D.KNRQNS..G.T..LV.NRIANAGDTQVIPNYSFIRAHDYD...AQDPIRRA..MIDHGI......IKNMQD..T..FTFDQLAQGMEFYYQDQNNPSgfKKYNDYNLPSAYAMLLTNKDTIPRVYYGDMYYEGGQYMQNETIYNRIISALLKARIKYVSGGQTMAT........DSS.G.KDlkd...........getDLLTSVRFGKGIMTSdqttTQ.DNSQ.D.YK.NQGIGVIVGNNPDLKLNNDKTITLHMGKAHKNQLYRALALSNDSGIDVYNSDDEAP-.--TLRTNDNGDLIFHKTntfvkqdgtiinyE........M........KGSLNALISGYLGVWVPVGASDSQDARTVATEAsSS.ND.GS.VFHSNAALDSNVIYE.GFSNFQAMPT..SPEQSTNVVIAANAEMFKKLGITSFELAPQYRSSGDTnyggmS.FLDSFLNNGYAFT.D..RYDL...G.....F.......N.KadgtpnP.....TK..YGTDQDLRNAIEALHKNGMQAIADWVPDQIYALPGKEVVTATRVDERGN....Q..LKDTDFVNLL...YVANTKSSGVDYQSKYGGEFLDKLKEEYSSLFKQN..................QVST.G............QPIDASTKIKQWSAKYMNGTNILHRGAYYVLKD.WATNQYFNVA-.KTD.EVFLPLQLQ.NKDSQTGFISDA-s................................................
U2KBZ8_9STRE/260-1062                 ...................................................ILMTWWPDAATKAAYANFWAKESL.I.SG.........S-.YRQ--NSANLDAATQNIQVAIEKKIAAEGNTNWLRDKM.......SQFVKSQNQWNSASEDkt......dyPNQD...HLQGGALLFSN..SD.....ATPQANS.DWRLLNRNPTNQTGQ--QKYFK..TN..YAGYELLLANDVDNSNPIVQAEQLNQFHYLMNWGEIVMNDKDANFDGVRVDAVDNVDADLLQIQRDYYKARYGTDQNEKNAIDHLSILEAWSGNDNDYVKDQNNFSLSIDNDQRSYMLAAFAN.....................PANKRG.NyLGQLAT..V.G..LK.NRTGN-NNSDPVPNYVFIRVHDSE...VQTRIAKI..IREKLG.....kTNADGL..T.nLTLDDLNKAFDIYNQDMNSVD..KQYYPNNLPMAYAWMLQNKDTVTRVYYGDMYTDNGQYMETKTPFYNAIEALLKGRIKYVAGGQAVGY........--N.Q.WN.................RVLTSVRYGKGANSI....ND.AGDA.T.TR.NSGMALLINNQPNFRAN--SNITLNMGAAHRNQAYRPLLLSTQNGTATYLNDSDVNS.SQYKYTDGQGRLTFNAS.............E........L........RGVSNVQVSGMIQVWVPVGAAADQDVRTAPSTS.AT.RD.GN.IYHQSDALDSQVIYE.GFSNFQAFAQ..NPDQYTNAVIAKNADLFKSWGITQFEMAPQYVSSEDG.....T.FLDSVIFNGYAFS.D..RYDL...A.....M.......S.K......N.....NK..YGSKQDLANAIKGLHAAGIKVLADWVPDQMYNLPGKEVVTATRVDEYGR....T..RSGATINKTP...YVVNTKTYGD-YQEQYGGKFLDDLQKLYPSLFTTK..................QIST.G............KPIDPSVKITNWSAKYFNGSNILGRGAKYVLSE.--GNKYLNLT-.-GG.KLFLPTVLN.NTY----------gqpqasskgfvskad..................................
G5KCZ1_9STRE/11-829                   ...................................................LLTTWWPSVDTQVNYLNYLSDYFG.I.EK.........T-.YSTEDSQASLNLAAEALQVKIEQEISAKNNVEWLREVM.......SSFVTTQSQWNKDTEN..........VGTD...HLQGGALLYVN..SD.....LTQWANS.DYRLLNRTPTYQTGT--TKYFK..AD.kTGGYDFLLANDVDNSNPVVQAVQLNQLYYLTNWGSIVFGDKNANFDGIRLDAVDNVNADLLQIYTNYFEAAYNVDKSEADALAHISILEAWSYNDPDYVQDTNVDGLAVDNGLRLSLLYSLTR.....................NTSERS.G.LEPLIS..S.EigLT.DRSTDSAYGDTTPSYTFVRAHDSE...VQTIIAQI..ISSKIN......PKTDGM..T..FTLDELKQAFEIYNADMNSVN..KEYTHYNIPAAYSLLLTNMESVPRIYYGDLYTDNGQYMETKSPYYDQITELLKARIKYSAGGQSMAVnyytpdstM--.-.-Ktdnqd......svlnqtGVLTSVRYGSGIMTA....DQ.TATDgN.PV.TSGIVTVISNNPDLKLASTEKVAVQVGIAHAGQYYRPLFLPTDNGLVSYSNDSDT--.TLRKLVDNNGFIYFTAD.............E........I........KGYQTVDMNGYLSVWVPVGASDDQDIRVAASTE.TY.SDgDK.TIKATAALDSQVIYE.GFSNFQDFVT..NDSQYTNKVIAENSELFASWGITTFEMAPQYVSSTDG.....S.FLDSIIQNGYAFT.D..RYDL...G.....M.......S.K......N.....NK..YGSAEDLRDALLALHSAGLQVIADWVPDQIYSLPNEEVVTATRVNDYGE....V..KEGAYINNTL...YVANTKSSGTDYQAKYGGAFLDYLQSQYSDLFTVN..................MIST.G............EPIDPSTKITTWKAEYFNGTNILGRGDGYVLSD.QATGKYFTVS-.-DT.GVFLPKQLT.SNSAVTGFYYDG-s................................................
GTFB_STRMU/269-1074                   ...................................................LLMTWWPSQETQRQYVNYMNAQLG.I.NK.........T-.YDDTSNQLQLNIAAATIQAKIEAKITTLKNTDWLRQTI.......SAFVKTQSAWNSDSEK..........PFDD...HLQNGAVLYDN.eGK.....LTPYANS.NYRILNRTPTNQTGKKDPRYTA..DN.tIGGYEFLLANDVDNSNPVVQAEQLNWLHFLMNFGNIYANDPDANFDSIRVDAVDNVDADLLQIAGDYLKAAKGIHKNDKAANDHLSILEAWSDNDTPYLHDDGDNMINMDNKLRLSLLFSLAK.....................PLNQRS.G.MNPLIT..N.S..LV.NRTDDNAETAAVPSYSFIRAHDSE...VQDLIRDI..IKAEIN......PNVVGY..S..FTMEEIKKAFEIYNKDLLATE..KKYTHYNTALSYALLLTNKSSVPRVYYGDMFTDDGQYMAHKTINYEAIETLLKARIKYVSGGQAMRN........QQV.G.NS.................EIITSVRYGKGALKA....TD.TGDR.T.TR.TSGVAVIEGNNPSLRLKASDRVVVNMGAAHKNQAYRPLLLTTDNGIKAYHSDQEA-A.GLVRYTNDRGELIFTAA.............D........I........KGYANPQVSGYLGVWVPVGAAADQDVRVAASTA.PS.TD.GK.SVHQNAALDSRVMFE.GFSNFQAFAT..KKEEYTNVVIAKNVDKFAEWGVTDFEMAPQYVSSTDG.....S.FLDSVIQNGYAFT.D..RYDL...G.....I.......S.K......P.....NK..YGTADDLVKAIKALHSKGIKVMADWVPDQMYAFPEKEVVTATRVDKFGK....P..VEGSQIKSVL...YVADSKSSGKDQQAKYGGAFLEELQAKYPELFARK..................QIST.G............VPMDPSVKIKQWSAKYFNGTNILGRGAGYVLKD.QATNTYFNISD.NKE.INFLPKTLL.NQDSQVGFSYDGK.................................................
A0A0D1LM29_9LACT/388-1183             ...................................................LLATWWPTKQTQADYVNYMNHALD.M.AN.........AS.VSAADSEATLTAATDAIQAVVEHQITVRQSTAWLRELM.......AAFVVTQPQWNKTSED..........VNDD...HLQGGALTFEN..NG.....DT-DANS.DYRLMNRTPTNQTGERLYHIDD..S-..LGGYELLLANDVDNSNPQVQAEQLNWLYYLMHFGDITADDPDANFDAIRIDAVDNVDADLLQLAAQYFRDAYGMATTDATSNKHLSILEDWSHNDPAYMQAHGNDQLTMDDYMHTQLIWSLTK.....................PEAQRG.T.MARFMD..F.Y..LT.NRANDDTENTAQPSYSFVRAHDSE...VQTVIAEI..VTKLHP......EAGNGL..M..PTEEQMAEAFKIYNADQKKAV..KTYTHYNMPSAYAMLLTNKDVIPRIYYGDLYTDDGQFMATKSPYFDAISTMLQARTKYVTGGQTMAV........---.D.QH.................DVLTSVRFGKGAMTA....ND.LGDA.E.TR.TEGVGLIISNNPKLQLGQQDNVVLHMGLAHANQAFRAVVLTTATGLTIYNDD-DAP-.--IRYTDNKGDLIFTNH.............D........V........YGVLNPQVSGFLAMWVPTGAPANQDARSTASTN.MS.TD.GS.AYHSNAALDSQVIFE.SFSNFQAMPT..SHDTYTNVVLANHADQLHDWGITSVQLAPQYRSSTDG.....T.FLDAIIQNGYAFT.D..RYDL...G.....F.......G.T......P.....TK..YGDDTDLRNVIKALHANGMQVMADFVPDQLYTLPGKELVQVTRTNNMGE....P..DTHSDIQHIL...YVTSTRGGG-DYQKQYGGEFLARLRERYPDLFTTR..................QIST.G............QTIDDSVKIKEWSAKYLNGTAIQGRGAGYVLRD.NGTNAYYKVTA.NDG.NVNLPKQLL.GQPVMTGFYHE--ad...............................................
Q03XV7_LEUMM/344-1142                 ...................................................LLMSWWPDKDTQVSYLKYMQSAGL.L.SD.........DVaLSNNDSMNSLTDTAMTVQKNIEEKIGLLGSTDWLKADM.......NQMVDSQSNWNISSES..........KGTD...HLQGGALLYVN..SD.....LTPNANS.DYRLLNRTPTNQKGQ---ITTN..GN..QGGYEMLLANDVDNSNPIVQAEQLNWLYYMMNIGSIAQNDPTANFDGYRVDAVDNVNADLLQIAGDYFKAAYGTNQSDANANNHISILEDWDNNDPAYVKAQGNNQLTMDFPMHLALKYSLNM.....................PSSARS.G.LEPAIS..T.S..LV.NRAADATENEAQPNYSFIRAHDSE...VQTVIAQI..IKDKIN......PSSDGL..T..VSTDEIAKAFEIYNADELKAD..KEYTAYNIPSSYALMLTNKDTIPRVYYGDLFTDDGQYMSAKSPYYDALTSLLQSRVKYVSGGQSMNM........TYLhN.NQ.................GLLTSVRYGKDAMTA....ND.TGTS.E.TR.TQGIGLIVGNKTDLNLNNDEQIVLNMGAAHKNQAYRALMLSTKDGLKIYNSDDEAP-.--VSYTDDQGRLIFKSD.............V........V........YGVSDAQVSGYLAAWVPVGANDSQDARTESSTT.AS.TD.GN.TYHSNSALDSQVIYE.GFSNFQAMPT..QADEYTNIKIAENAQLFKSLGITSFELAPQYRSSTDN.....S.FLDSVIQNGYAFT.D..RYDI...G.....Y.......N.T......P.....TK..YGTVDQLLDALRALHAQGIQAINDWVPDQIYNLPGEEIVTASRTNGSGK....V..NESSVINNTL...YDSRTVGGGE-YQAIYGGAFLDKLKQDYPELFETK..................QIST.G............EAMNPDVKITEWSAKYFNGSNIQGRGAWYVLKD.WSTNQYFNVS-.-SG.SEFLPKQLL.GEKTSTGFTNV--dn...............................................
Q03XV7_LEUMM/2023-2821                ...................................................LITVWWPNKDVQVNYLNFMKKNGL.L.DT.........SSqFNLQFDQYDLNVAAQKVQVAIEKRISKEKSTDWLKDLLfeahedtPSFVKQQFIWNKDSEYq........gQGDA...WFQGGYLKYDN..SE.....LTPTTNS.DYR--------ESGN-------..--..--TLDFLLANDVDNSNPAVQAENLNWLHYLMNFGTITANDDDANFDSIRIDAVDFIDNDAIQRTYDYMRDAYKVDASEDNANKHISLVEAGLDAGTSTIKNNALVESNFREAATLSLANQSGK.....................NSSLTN.M.LQDIDG.gQ.I..IA.DHANNATENEATPNYSIIHAHDKG...IQEKVGAA..ITDVTG......--ADWT..N..FTDDQLKEGLAAYYQDQRSTN..KKYNIYNLPSIYALMLTNKDTVPRVYYGDMYQDDGQYMEKQSIYYDAIVSLMNTRKSYVSGGQTMDV........---.D.EH.................GLLKSVRFGKDAMTA....SE.LGTN.E.TR.TEGVGVLVGNDSSLKLNDSDTVTLEMGAAHKNQEYRAALLTTSDGIVTYDADNDAP-.--TIWTDDRGTLTFSNK.............E........IagqdytsvQGFANPQVSGYLAVWVPVGASDDQDARTAASTD.KN.TD.DK.VLHSNAALDSNLIYE.GFSNFQPKAT..TNDELTNVVIAKNANLFEKWGITSFEMAPQYRSSGDH.....T.FLDSTIDNGYVFT.D..RYDL...G.....F.......E.T......P.....TK..YGTDKDLRTAIKALHQSNMQVMADVVDNQVYNLSGQEVVSASRAGVYGN....D..VS-TGFGTQL...YAVNSVGGGK-YQAQYGGEYLNELKQQYPDLFEAKtyd...........ywvkNYSNdGsdpyytlsqntrKDMPSSEVIKQWSAKYMNGTNVLGNGMGYVLKD.WNTGEYFKIG-.EKN.AD-------.-------------fitn.............................................
Q04GD2_OENOB/292-1115                 ...................................................LLMSWWPDKTTQVNYLNYMKNLGL.S.DS........pTN.FTNDENQGRLSKAAENVQVKIERKITQEGQTQWLKEVI.......TNFVKSQPNWNISSESqt......sgNGKD...HLQGGALLYVN..ND.....KTPDANS.DYRLLNRTPTNQTGTPLYSIDP..T-..QGGYDFLLANDVDNSNPVVQAEQLNWMYYLLNFGSITGNESNANFDSIRVDAVDNVDADLLQIAADYFKAAYGVDQNDAKADQHVSILEDWSDNDSEYVKDQGSNQLSMDNKMRLSLKYSLTIpv................vdkESNKRS.G.LEPLIS..N.N..LV.NRSEDSSTNGAQPNYSFVRAHDSE...VQTVIAEI..IKEKID......PDSDSL..T..PTIDQLTAAFKIYDADQLKTR..KEFTQYNIPSTYAMILTNKDTVPRVYYGDLYTDDGQYMANKSPYYDSIDNLLKSRIKYVTGGQSMSI........QYV.Q.GDgsma........kdsyrGVLTSVRYGKDAMNE....KD.QGTQ.E.TR.TEGLAVIESNNPDLKLSSSDQIVINMGAAHKNQAYRPMLLTKTNGLASYQSDESVPV.NEIRYTNADGQLIFTSE.............D........I........IGTANPQVSGYLAVWVPVDAKDTQDARSQSSDQ.ST.ND.GQ.ILHSNAALDSQVIYE.SFSNFQSLPT..KTSEYANVKIAENTDLFNSWGITNFEFPPQYRSSTDN.....S.FLDSIVQNGYAFT.D..RYDL...G.....F.......N.T......P.....TK..YGTVDQLRTSLIALHKAGIKAMADWVPDQIYNLTGMQIVTAKRVNDSGI....Y..DQDSVINDSL...YAAQTKGGGT-YQAMYGGAFLDKIKEMYPDLFQMN..................QIST.G............VPIDPNEKIKEWSAKYFNGSNIQGRGAYYVLKD.WASNSYFKVGSdNST.DVFLPKQLL.NEPSNTGFISDS-q................................................
GTFC_STRMU/295-1103                   ...................................................LLMTWWPDQETQRQYVNYMNAQLG.I.HQ.........T-.YNTATSPLQLNLAAQTIQTKIEEKITAEKNTNWLRQTI.......SAFVKTQSAWNSDSEK..........PFDD...HLQKGALLYSN.nSK.....LTSQANS.NYRILNRTPTNQTGKKDPRYTA.dRT..IGGYEFLLANDVDNSNPVVQAEQLNWLHFLMNFGNIYANDPDANFDSIRVDAVDNVDADLLQIAGDYLKAAKGIHKNDKAANDHLSILEAWSYNDTPYLHDDGDNMINMDNRLRLSLLYSLAK.....................PLNQRS.G.MNPLIT..N.S..LV.NRTDDNAETAAVPSYSFIRAHDSE...VQDLIRNI..IRAEIN......PNVVGY..S..FTMEEIKKAFEIYNKDLLATE..KKYTHYNTALSYALLLTNKSSVPRVYYGDMFTDDGQYMAHKTINYEAIETLLKARIKYVSGGQAMRN........QQV.G.NS.................EIITSVRYGKGALKA....TD.TGDR.T.TR.TSGVAVIEGNNPSLRLKASDRVVVNMGAAHKNQAYRPLLLTTDNGIKAYHSDQEA-A.GLVRYTNDRGELIFTAA.............D........I........KGYANPQVSGYLGVWVPVGAAADQDVRVAASTA.PS.TD.GK.SVHQNAALDSRVMFE.GFSNFQAFAT..KKEEYTNVVIAKNVDKFAEWGVTDFEMAPQYVSSTDG.....S.FLDSVIQNGYAFT.D..RYDL...G.....I.......S.K......P.....NK..YGTADDLVKAIKALHSKGIKVMADWVPDQMYALPEKEVVTATRVDKYGT....P..VAGSQIKNTL...YVVDGKSSGKDQQAKYGGAFLEELQAKYPELFARK..................QIST.G............VPMDPSVKIKQWSAKYFNGTNILGRGAGYVLKD.QATNTYFSLV-.-SD.NTFLPKSLV.NPNHGT-------sssvtglvfdgk.....................................
#=GR GTFC_STRMU/295-1103        SS    ...................................................HHHHHTSSHHHHHHHHHHHHTSGG.S.GG.........S-.EEE-SS-GGGGGG--S---TT--TTTTTSS--TT--SS.......--SSEEE-TTSHHHHH..........THHH...S-GGG---EEE.TTG.....HHHHHHH.HHHHHH-TTTBHHHHHTT--EE.--S..HHHHHHHTTSSSBEE-HHHHHHHHHHTTS-GGG---STHHHHSSSS-TSEE--SSESS-EEE-S--SSTTTHHHHHHHHHHHT-TT--TT---HHHHHHHHHHHHHHHH-SS-SSS-S-HHHH.....................SSSSTT.S.-TTHHH..H.H..HH.H--S-EEEEEEEETTEEEEEEEE-...BSSTT---..HHHT--......S-TT-B..T..EEEEE--GGGTT-EEEEEEEE..SSEEE--STGGGGGG-EE--TTSEEEEETTT-B-EESSS-EEEEEEEEETT--TT---------SB-........SHH.H.-E.................SHHHHHHHTHHHHHH....EE.----.-.--.-SSHHHHTT-SSSBS-TT-SSSSS-BTTB-HHHHHHHHHHHHHTT-EEEEEE--S-E.--SEEEEEEEEEE-TTS.............E........S........THHHHHHH-HHHHHSB-TTTSSB--TTS--SS-.GG.EE.EE.-SS-TT-B-EETTTT.E-BEETTSEB..HHHH--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.....X.XXXXXXXXXXXXX.X..XXXX...X.....X.......X.X......X.....XX..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....X..XXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..................XXXX.X............XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX-.-XX.XXXXXXXXX.XXXXXX-------XXXXXXXXXXXX.....................................
A8AVK3_STRGC/334-1148                 ...................................................LLMAWWPDKRTQINYLNYMNQENL.G.IG.........A-.FESKTEQVLLTNAVQQVQRKIEERISKEGDTKWLRTLM.......SAFVKTQPNWNIKTESet......tgTNKD...HLQGGALLYTN..SD.....KTSHANS.RYRLLNRTPTSQTGT--PKYFIdkS-..NGGYEFLLANDFDNSNPAVQAEQLNWLHYMMNFGSIVANDPTANFDGVRVDAVDNVNADLLQIASDYFKSRYKVGESEEEALKHLSILEAWSDNDPDYNKDTKGAQLAIDNKLRLSLLYSFMR.....................KLSIRS.G.VEPTIT..N.S..LN.DRSTENKNGERTANYIFVRAHDSE...VQTVIADI..IRENIN......PNTDGL..T..FTMDELKQAFKIYNEDMRKAD..KKYTQFNIPTAHALMLSNKDSITRVYYGDLYTDDGQYMEKKSPYHDAIDALLRARIKYVAGGQDMKVt......yMGV.P.REadk..........wsynGILTSVRYGTGANEA....TD.EGTA.E.TR.TQGMAVIASNNPNLKLNEWDKLQVNMGAAHKNQYYRPVLLTTKDGISRYLTDEEVPQ.SLWKKTDANGILTFDMN.............D........I........AGYSNVQVSGYLAVWVPVGAKENQDARVTASKK.KN.AS.GQ.VYESSPALDSQLIYE.GFSNFQDFAT..RDDQYTNKVIAKNVNLFKEWGVTSFELPPQYVSSQDG.....T.FLDSIIQNGYAFE.D..RYDM...A.....M.......S.K......N.....NK..YGSLDDLLNALRALHSVNIQAIADWVPDQIYNLPGKEVVTATRVNNYGT....Y..REGAEIKEKL...YVANSKTNGTDYQGKYGGAFLDELKAKYPEIFERV..................QISN.G............QKMTTDEKITKWSAKYFNGTNILGRGAYYVLKD.WGSKEYLSNK-.-NG.ETALPKQLV.NKEASTGFVKDTN.................................................
B1YMN6_EXIS2/16-200                   .......................................vatssfgvapkq------------------------.-.--.........--.--------------------------------------.......----------------..........----...-----------..--.....-------.----------------------..--..---------------------------------------------------------------------------------------------------------------------------.....................------.-.------..-.-..--.------------------------...--------..------......------..-..---------------------..-------------------------------------------------------------------........---.-.--.................---------------....--.----.-.--.---------------------------------------------------------.-----------------.............-........-........---------------------------------.--.--.AA.AYTSGEKLDNHVIFQ.SFSLYQPYD-..-SNMY--RTLAKKGDLLNSWGVTDVWMPPAYRSFDMA.....R.YM-----EGYAIA.D..RYDL...G.....EfpqgpggT.T......A.....TK..YGKASHLEMMVDMLHDDNIKVQMDLVPNQMLGLNKREAVFVRRATSSGElftnP..YTGGQTTKTLatpYLAYTKGGGQ-GQEKYG------------------..................----.-............---------------------------------.-----------.---.---------.-------------yl...............................................
A0A062XMN8_LEUPS/328-546              ...................................................ILITWQPDIVTEVNYLNMMAANGL.LsIN.........AP.FTTASDLAIMNDAVRAVQKNIEIRISQEKSTDWLKTLM.......TQFINTQPQWNEVSES..........PSND...HLQGGALTYVN..SP.....LTPDANS.NFRLLNRTPTNQSGTTRYDTDK..SE..-GGFELLLANDVDNSNPVVQAEQLNWLYYLMNFGSITANDPTANFDGIRVDAVDNVDADLLQIASDYFKLAYGTSLSDTNANQHLSIL-----------------------------------.....................------.-.------..-.-..--.------------------------...--------..------......------..-..---------------------..-------------------------------------------------------------------........---.-.--.................---------------....--.----.-.--.---------------------------------------------------------.-----------------.............-........-........---------------------------------.--.--.--.---------------.----------..-------------------------------------.....-.-------------.-..----...-.....-.......-.-......-.....--..-------------------------------------------------....-..----------...-----------------------------------..................----.-............---------------------------------.-----------.---.---------.-------------.................................................
A5VL73_LACRD/551-1359                 ...................................................LLMYTWPSKDVEAKFIKYFVDNGY.T.NTdygltkdnvTN.LSQDTDTQTLNKYARNLRFVIEKSIAANKSTGPLANDI.......NKFMLTIPELSAKSELpveysngyvpDVSG...SIDNNQLIFINnnSDnqakgNTSYADS.NYRLMNRTINNQTNN--DNSDQ..S-..---PELLVGNDIDNSNPAVQAENFNWEYFLLNYGKLMKYNADGNFDGFRVDAADNIDADVLDQLGQLVNDMYHTKGNQENANNHLVYNEGYHSGAARMLNDKGNPELFMDAGYFYTLENVLGQ.....................AENKRD.N.VNNLIT..N.S..VV.NRANDITENTATPNWSFVTNHDQR...-KNVINQI..IIDNHP......NIPDIM..AnsYKSTYAQKAWDEFYADQAKAD..KKYAQYNLPAQYALLLSNKDTVPQVYYGDLYKETDQYMKTKSMYYDAITTLMKARGEFVNGGQTMTK........---.V.ND.................NLITSVRYGKGVVDV....SS.NGTDpL.SR.TTGMAVIVGNNPSMS---EQVVAINMGLAHANEQYRNLIDSTADGLT-YNSNGSV-N.PSVLTTDSKGILRVT--.............-........V........KGYSNPYVSGYLSVWVPLI-NGTQNARTSAQEV.RN.VP.GK.VFTSNAALDSHMIYE.DFSLFQPEPT..TVNEHAYNVIKDNVALFNQLGITDFWMAPSYT-----.....P.FNTSRYNEGYAMT.D..RYNL...G.....T.......AdN......P.....TK..YGNGEELSNAIAALHQAGLKVQEDLVMNQMIGFSTQEAVTVTRVDRDAK....QlsVDGQTFADQI...YFGYTRGGGQ-GQQDYGGKYLAELKQKYPDLFTTK..................AAST.G............VAPDPNTRITEWSAKYENGTSLQNVGIGLAVKMpNGYYAYLNDGN.NKAfATTLP----.-------------daissadyyan......................................
Q2UIS6_ASPOR/324-482                  .................lvvnlcrtsytkggdlrkifkgtlvqskpenaln------------------------.-.--.........--.--------------------------------------.......----------------..........----...-----------..--.....-------.----------------------..--..---------------------------------------------------------------------------------------------------------------------------.....................------.-.------..-.-..--.------------------------...--------..------......------..-..---------------------..-PVAQYFKPLAYALVLLRKDGHPCVFYGDLYGTLGDKPLKRA-CKGKLPILTRARKLYAYGEQQDYF........---.D.QA.................NCIGFVRYGNA----....--.----.-.--.---------------------------------------------------------.-----------------.............-........-........---------------------------------.--.--.--.---------------.----------..-------------------------------------.....-.-------------.-..----...-.....-.......-.-......-.....--..-------------------------------------------------....-..----------...-----------------------------------..................----.-............---------------------------------.-----------.---.---------.-------------rhpsgmacimsngaaaekrmyvgpkhaneqwtdimqshesvvtida...
U2KIM5_9STRE/272-1095                 ...................................................VLMSWWPNKDTQVAYLNYMSKALG.G.KE.........E-.FTTETSQLTLNTAAELIQAKIEARVSKEQGTKWLREAM.......AAFVATQSRWNKDSEQ.........yDKAD...HLQGGALLYTN..NN.....LTEWANS.NWRLLNRTPTRQDGK--THYSK..AD.kYGGYEFLLANDVDNSNPVVQAEMLNQIHYLMNWGEIVMGDKNANFDGIRVDAVDNVNADTLQLYTNYFNSVYGVNKSEAQALAHISVLEAWSYNDNDYNQDTNGAALAMDNGLRFSLLYTLTR.....................PLNERTpG.MSTLIKseY.G..LT.DRTKNDKYGDTQPSYVFVRAHDSE...VQTVIAQI..IKEKID......PTTDGF..T..FTLDQLKQAFEIYNKDMNSVN..KHYTHYNIPAAYAVMLSNMESVTRVYYGDLFTDDGQYMASKSPYYDAINTLLRARIRYAAGGQIMEH........NSY.K.PSaamkvahpdagnvlgnsEVLVSVRFGQDVMSA....DDmTGGK.L.AK.TSGMFTLISNNPELELDVNEEIKVNVGKIHAGQAYRPLLLTTDKGLQKYLNDSDT--.KLTKVADKDGFITFKGS.............E........I........KGYKQVEVNGYLSVWVPVGAKADQDIRVVPSTA.AKgEK.DK.TYTASQALESQLIYE.GFSNFQDFVQ..KDSQYTNKKIAENTDLFKAWGVTSFEMAPQYVSATDG.....T.FLDSIIENGYAFT.D..RYDL...A.....M.......S.K......N.....NK..YGSKEDLANALKALHAAGIQAIADWVPDQIYQLPGKEVVTASRVDNYGR....V..KVDQPLVEKL...YLANTKSSGKDFQAKYGGEFLAELQKKYPEMFTTK..................MIST.G............KTIDPSVKLKEWSAKYFNGTNVLDRGTDYVLSD.EGTGKYFTVN-.-EK.GDFLPASLTgNKDAKTGFYNDGK.................................................
GTFD_STRMU/281-1103                   ...................................................LLMSWWPDKQTQIAYLNYMNQQGL.G.TG.........EN.YTADSSQESLNLAAQTVQVKIETKISQTQQTQWLRDII.......NSFVKTQPNWNSQTESdt......saGEKD...HLQGGALLYSN..SD.....KTAYANS.DYRLLNRTPTSQTGK--PKYFE.dNS..SGGYDFLLANDIDNSNPVVQAEQLNWLHYLMNYGSIVANDPEANFDGVRVDAVDNVNADLLQIASDYLKAHYGVDKSEKNAINHLSILEAWSDNDPQYNKDTKGAQLPIDNKLRLSLLYALTRplek.............dasnKNEIRS.G.LEPVIT..N.S..LN.NRSAEGKNSERMANYIFIRAHDSE...VQTVIAKI..IKAQIN......PKTDGL..T..FTLDELKQAFKIYNEDMRQAK..KKYTQSNIPTAYALMLSNKDSITRLYYGDMYSDDGQYMATKSPYYDAIDTLLKARIKYAAGGQDMKIt......yVEG.D.KShmd..........wdytGVLTSVRYGTGANEA....TD.QGSE.A.TK.TQGMAVITSNNPSLKLNQNDKVIVNMGTAHKNQEYRPLLLTTKDGLTSYTSDAAA-K.SLYRKTNDKGELVFDAS.............D........I........QGYLNPQVSGYLAVWVPVGASDNQDVRVAASNK.AN.AT.GQ.VYESSSALDSQLIYE.GFSNFQDFVT..KDSDYTNKKIAQNVQLFKSWGVTSFEMAPQYVSSEDG.....S.FLDSIIQNGYAFE.D..RYDL...A.....M.......S.K......N.....NK..YGSQQDMINAVKALHKSGIQVIADWVPDQIYNLPGKEVVTATRVNDYGE....Y..RKDSEIKNTL...YAANTKSNGKDYQAKYGGAFLSELAAKYPSIFNRT..................QISN.G............KKIDPSEKITAWKAKYFNGTNILGRGVGYVLKD.NASDKYFELK-.-GN.QTYLPKQMT.NKEASTGFVNDGN.................................................
B1MZT6_LEUCK/1-112                    ..................................................m------------------------.-.--.........--.--------------------------------------.......----------------..........----...-----------..--.....-------.----------------------..--..---------------------------------------------------------------------------------------------------------------------------.....................------.-.------..-.-..--.------------------------...--------..------......------..-..---------------------..-------------------------------------------------------------------........---.-.--.................---------------....--.----.-.--.---------------------------------------------------------.-----------------.............-........-........---------------------------------.--.--.--.---------------.----------..-------------------------------------.....-.-------------.-..----...-.....-.......-.-......-.....--..-------------------------------------------------....-..-----INNTL...YDSRTVGGGE-YQEKFGGLFLDQLKKDYPSLFETK..................QIST.N............QPMNPDVKIKEWSAKYFNGSNIQGRGAWYVLKD.WATNQYFNVS-.-SD.NGFLPKQLL.GEKTSTGFITE--ng...............................................
U2KIP9_9STRE/1-53                     ...................................................------------------------.-.--.........--.--------------------------------------.......----------------..........----...-----------..--.....-------.----------------------..--..---------------------------------------------------------------------------------------------------------------------------.....................------.-.------..-.-..--.------------------------...--------..------......------..-..---------------------..-------------------------------------------------------------------........---.-.--.................---------------....--.----.-.--.---------------------------------------------------------.-----------------.............-........-........---------------------------------.--.--.--.---------------.----------..-------------------------------------.....-.-------------.-..----...-.....-.......-.-......-.....--..-------------------------------------------------....-..----------...-----------------------------------..................----.-............---------TNWSAKYFNGSNILGRGAKYVLSD.--GKQYFNLT-.-SG.KLYLPTALL.SNATTT-------tqps.............................................
U2J7Y6_9STRE/274-1078                 ...................................................VLMSWWPDKDTQVAYVNYMNKYLS.A.NE.........TE.VTNETSQVDLNKEAQSIQTKIEQKITSDNSTQWLRTAM.......EAFVATQPKWNMSTEN.........fNKGD...HLQGGALLYTN..SD.....LTPWANS.DYRLLNRTPTQQDGT--KKYFT.eGG..EGGYEFLLSNDVDNSNPVVQAEQLNQLHYLMNWGDIVMGDKDANFDGVRVDAVDNVNADLLQVYSNYFKDNYKVTDSEANALAHISILEAWSLNDNQYNEDTNGTALSIDNSSRLTSLAVLTK.....................QPGQRL.D.LSNLIS..E.S..VNkERANDTAYGDTIPTYSFVRAHDSE...VQTVIAKI..VKEKID......TNSDGY..T..FTLDQLKDAFKIYNEDMAKVN..KTYTHYNIPAAYALLLSNMESVPRVYYGDLYTDDGQYMAKKSPYYDAIATMLQGRIAYVSGGQSEEV........HKV.NgNN.................QILSSVRYGQDLMSA....DDtQGTD.L.SR.TSGMVTLVSNDPNLNLG-SDSLTVNVGKAHANQAYRPLILGTKDGVQSYLKDSDT--.NIVKYTDANGNLTFTAD.............D........I........KGYSTVDMSGYLAVWVPVGAKDGQDVRVAADTN.QK.AD.GK.SLKTSAALDSQVIYE.GFSNFQDFAN..NDADYTNKKIAENADFFKKLGITSFEMAPQYVSATDG.....S.FLDSIIENGYAFS.D..RYDL...A.....M.......S.K......N.....NK..YGSKDDLANALKALHANGIQAIADWVPDQIYQLPGEEVVTAKRTNSYGK....P..TFDAFINNTL...YAANTKSSGSDYQAQYGGAFLDELKAKYPDMFSVN..................MIST.G............KPIDSSTKIKQWEAKYFNGTNVLGKGAGYVLSD.DATGKYFTVN-.-EN.GDFLPASFTgDQNAKTGFYYDG-t................................................
B1YMN6_EXIS2/334-766                  .........................syqndnsgidiedqflfvdetgfplq------------------------.-.--.........--.--------------------------------------.......----------------..........----...-----------..--.....-------.------------------AYNK..TM..TNNDEFLLGVDLANSNTEVIKEQKNWMKWMLE---------TYKFDGFRIDAASHYDTAIL-------KAEAQVAKEHFGKKEHLSYIESYKSEQKAYMKANNDEQLIMDSPLYFTMRTALGN.....................EASKR-.P.LSAIAT..G.S..TI.NRAGNG-STDVSANWSFVNNHDQEknrVNQIMLDLygIKTGIQykageePKSFEK..M..YDKDTEKQALGIYNAELASTK..KKYSVDNVVSQYAFLLTNKDTVPTVYYGDLYQTDASYMSKQTPYYDEITNLLKVRKQYAYGAQKVAY........HTT.N.TSkv............agsHLISSVRLGKD----....--.----.-.-R.NTGVATVIGKKSTL----NTTIKVDMGKQHTNQVFVD-----ASGVTQT----K---.---LVTDKNGILTV---.............P........V........KGMRTAEVNGYLGVFVPQTTKAP----------.--.--.--.---------------.----------..-------------------------------------.....-.-------------.-..----...-.....-.......-.-......-.....--..-------------------------------------------------....-..----------...-----------------------------------..................----.-............---------------------------------.-----------.---.---------.-------------tatiekasvyqgkginlktkvlntsstvssiryqv..............
U2J3Q1_9STRE/258-1001                 ...................................................VLMSWWPDTATKTAYVNFWAKEGL.I.SN.........Q-.-----AARNIDTAVQSIQTAIEKKISTEGNTAWLRSKM.......TQFVQSQSQWNINSENpt......syPSQD...HLQGGALLFSN..SD.....ATAQANS.NWRLLNRNPSQQDGH--VNYHK..SS..YGGYELLLANDVDNSNPIVQAEQLNHFHYLMNWGEIVMGDKDANFDGVRVDAVDNVDADLLQIQRDYYKAKYGTDKSEKNAIDHLSILEAWSGNDNDYVKDQNNFSLSIDNDQRSGMLKAFGY.....................ASAYRG.N.LGNLAT..A.G..LK.KRSNTS-SGDPIPNYVFIRAHDSE...VQTRIATV..IRERLG.....mGNVDGL..T.nITLDDLEKAFAIYNQDMYSVD..KQYYINNLPMAYTWMLQNKDTVTRVYYGDMYTDNGQYMATKTPFYNAIETMLKARIKYVAGGQQAGY........NQG.W.NG.................GILTSVRYGKGADSV....TD.RGTS.E.TR.TSGMAVLINNMPNFQ--ASSGVTLSMGAAHKNQAYRPLLLSTKDGIATYLNDRDVSS.SQYKYTDSQGRLSFSAS.............E........L........RSVANVQVSGMIQVWVPVGAADNQDVRTAPSTA.KT.TD.GN.IYHQTDALDSQVIYE.GFSNFQAFAK..TPEQYTNAVIAKNADLFKSWGITQFEMAPQYVSSEDG.....T.FLDSIILNGYAFS.D..RYDL...A.....M.......S.K......N.....NK..YGSKEDLANAIKALHAAGIKVLSDWVPDQMYNLPGKEVVTATRVNQYGQ....T..TARAAINKTP...YVVNTRTYGD-YQEQYGGKFLDELQKLYPSLFMTK..................QIST.G............KAIDPSVKITNWS--------------------.-----------.---.---------.-------------.................................................
B1MZT6_LEUCK/994-1791                 ...................................................LITVWWPNKNVQVNYLNFMKANGLlI.TA.........AQ.YTLHSDQYDLNQAAQDVQVAIEKRIASEHGTEWLQKLLfesqnnnPSFVKQQFIWNKDSEYh........gGGDA...WFQGGYLKYGN..NP.....LTPTTNS.DYR--------QPGN-------..--..--AFDFLLANDVDNSNPVVQAENLNWLHYLMNFGTITAGQDDANFDSIRIDAVDFIHNDTIQRTYDYLRDAYQVQQSEAKANQHISLVEAGLDAGTSTIHNDALIESNLREAATLSLTNEPGK.....................NKPLTN.M.LQDVDG..GtL..IT.DHTQNSTENQATPNYSIIHAHDKG...VQEKVGAA..ITDATG......--ADWT..N..FTDEQLKAGLELFYKDQRATN..KKYNSYNIPSIYALMLTNKDTVPRMYYGDMYQDDGQYMANKSIYYDALVSLMTARKSYVSGGQTMSV........---.D.NH.................GLLKSVRFGKDAMTA....ND.LGTS.A.TR.TEGLGVIIGNDPKLQLNDSDKVILDMGAAHKNQKYRAVILTTRDGLATFNSDQAP--.--TAWTNDQGTLTFSNQ.............EingqdntqI........RGVANPQVSGYLAVWVPVGASDNQDARTAATTT.EN.HD.GK.VLHSNAALDSNLIYE.GFSNFQPKAT..THDELTNVVIAKNADVFNNWGITSFEMAPQYRSSGDH.....T.FLDSTIDNGYAFT.D..RYDL...G.....F.......N.T......P.....TK..YGTDGDLRAAIQALHHANMQVMADVVDNQVYNLPGKEVVSATRAGVYGN....D..DA-TGFGTQL...YVTNSVGGGQ-YQEKYAGQYLEALKAKYPDLFEGKaydywyknyandgsnpyyTLSH.Gd..........rESIPADVAIKQWSAKYMNGTNVLGNGMGYVLKD.WHNGQYFKLD-.-GD.KSTLP----.-------------qi...............................................
U2IKC9_9STRE/263-1069                 ...................................................LLMAWWPDTETKRNYVNYMNKVVG.I.DK.........T-.YTAETSQADLTAAAELVQARIEQKITSENNTKWLREAI.......SAFVKTQPQWNGESEK..........PYDD...HLQNGALLFDN.qTD.....LTPDTQS.NYRLLNRTPTNQTGSLDSRFTY.nANdpLGGYEFLLANDVDNSNPVVQAEQLNWLHYLLNFGTIYAKDADANFDSIRVDAVDNVDADLLQISSDYLKAAYGIDKNNKNANNHVSIVEAWSDNDTPYLHDDGDNLMNMDNKFRLSMLWSLAK.....................PLDKRS.G.LNPLIH..N.S..LV.DREVDDREVETVPSYSFARAHDSE...VQDLIRDI..IKAEIN......PNAFGY..S..FTQDEIDQAFKIYNEDLKKTD..KKYTHYNVPLSYTLLLTNKGSIPRVYYGDMFTDDGQYMANKTVNYDAIESLLKARMKYVAGGQAMQN........YQI.G.NG.................EILTSVRYGKGALKQ....SD.KGDA.T.TR.TSGVGVVMGNQPNFSLD-GKVVALNMGAAHANQEYRALMVSTKDGVATYATDADASKaGLVKRTDENGYLYFLND.............D........L........KGVANPQVSGFLQVWVPVGAADDQDIRVAASDT.AS.TD.GK.SLHQDAAMDSRVMFE.GFSNFQSFAT..KEEEYTNVVIANNVDKFVSWGITDFEMAPQYVSSTDG.....Q.FLDSVIQNGYAFT.D..RYDL...G.....M.......S.K......A.....NK..YGTADQLVKAIKALHAKGLKVMADWVPDQMYTFPKQEVVTVTRTDKFGK....P..IAGSQINHSL...YVTDTKSSGDDYQAKYGGAFLDELKEKYPELFTKK..................QIST.G............QAIDPSVKIKQWSAKYFNGSNILGRGADYVLSD.QVSNKYFNVA-.-SD.TLFLPSSLL.GKVVESGIRYDGK.................................................
Q03VD3_LEUMM/352-1171                 ...................................................LLMTWWPDKATQVNYLNAMKYLDA.T.ET.........ETvYTSDDSQDALNKAAQNIQVKIEEKISQEGQTQWLKDDI.......SKFVDSQSNWNIASES..........KGTD...HLQGGALLYVN..SD.....KTPDANS.DYRLLNRTPTNQTGT--PLYTT.dPT..QGGYDFLLANDVDNSNPVVQAEQLNWMYYLLNFGSITNNDADANFDSIRVDAVDNVDADLLQIAADYFKAAYGVDKSDAISNQHVSILEDWSDNDAEYVKDNGDNQLSMDNKLRLSLKYSLTMpa................vdqYGNKRS.G.LEPFLT..N.S..LV.DRTNDSTDNTAQPNYSFVRAHDSE...VQTVIAEI..IKQRID......PDSDGL..S..PTMDQLTEAFKIYNADQLKTD..KEFTQYNIPSTYATILTNKDTVPRVYYGDMYTDDGQYMATKSLYYDAIDTLLKSRIKYVSGGQTMSMk......yMQG.D.SSmaa..........dsyrGILTSVRYGNGAMTA....TD.AGTN.E.TR.TQGIAVIESNNPDLKLSSTDQVVVDMGIAHKNQAYRPALLTTKDGIDTYVSDSDVSQ.SLIRYTNSNGQLIFNSS.............D........I........VGTANPQVSGYLAVWVPVGASDTQDARTESSTA.TT.AD.GQ.TLHSNAALDSQVIYE.SFSNFQSTPT..TEAEYANVQIANNTDLYKSWGITNFEFPPQYRSSTDS.....S.FLDSIIQNGYAFT.D..RYDL...G.....F.......N.T......P.....TK..YGTVDQLRTAIKALHATGIKAMADWVPDQIYNLTGKEVVAVQRVNNSGI....Y..NQDSVINKTL...YASQTVGGGE-YQALYGGEFLDEIKKLYPSLFEKN..................QIST.G............VPMDASEKIKEWSAKYFNGTNIQGRGAYYVLKD.WATNEYFKVSTsSNS.SVFLPKQLT.NEESNTGFIS---tdg..............................................
G9WG05_9LACT/281-1082                 ...................................................ILTTWWPDKQTEVNYLNYMKTQGF.I.TN.........DQdFKLSDDQLLLNHAAQSVQGEIEKKISQQGSTDWLKTLL.......QTFINQQPSWNGESED..........PGSD...HLQGGALTFVN..SP.....LTPDSNS.NFRLLNRTPTNQTGT--PQYDT.dAS..LGGFELLLANDVDNSNPVVQAEQLNWLYYLLNFGSITADDPNANFDGIRIDAVDNVDADLLQIAAAYFKDAFKSGSNDQTTNQHLSILEDWSHNDPEYMKAQGYPQLTMDDYMHTQLIWSLTK.....................PDNIRG.T.MQRFMD..Y.Y..LV.NRANDSTNNEAVANYSFVRAHDSE...VQTVIAQI..ISDLYP......NSGSGL..I..PTTDQLQAAFEVYNADMKSDV..KKYTQYNIPSAYAMLLTNKDTVPRVYYGDMYTDDGDYMANKSPYFDAISTLLKARVKYAAGGQSMAV........---.D.KN.................DILTSVRFGQNAMLA....SD.SGDN.Q.TR.QEGIGVIVSNNSHLKLAENDQVVLHMGAAHKNQAFRALLLTIESGLENFDTDLQAP-.--VKYTDANGDLIFTAA.............E........L........AGYLNPEVSGYLSAWVPVGAADNQDARTAADSA.TS.TD.GN.VFHSNAALDSNVIFE.GFSNFQSIPTaeQHDDFTNVKIAENAGLFKDWGITSFQLAPQYRSSTDS.....T.FLDSIIQNGYAFT.D..RYDL...G.....F.......D.T......P.....TK..YGDVDDLRAAIKALHANNIQVMADWVPDQIYNLQNPEIITVNRTDSYGQ....P..IAGSDLQNDL...YLAYTNGGGQ-YQTKFGGAFLEKLQQLYPDLFTKT..................QIST.G............QTIDPSQKITEWSAKYFNGSNIQGRGAYYVLRD.SGTDQYFKVISnDEN.EAFLPKQLT.NQPGETGFSQDD-q................................................
A0A062XKC4_LEUPS/1-568                .................................................ms------------------------.-.--.........--.--------------------------------------.......----------------..........----...-----------..--.....-------.----------------------..--..----------------------------------------------------------------------------------------------------KTGSNQLTMDTYTQQQLLFSLTK.....................TVGNRA.D.MRRFLE..Y.F..MI.NRANDATENVATPNYSFVRAHDSE...VQTVIATI..IKDLHP......DVVNSL..A..PNQAQLEEAFAVYNADMNRVD..KQYTQYNMPSAYAMLLTNKDTIPRVYYGDLYTDDGEYMGTQTPYYDAIVNLLQSRVKYVAGGQSMAV........---.D.QH.................DILTSVRYGKNLADA....NA.TSDD.L.TSiNSGIGVIVSNNPNLSLASGETVVLHMGIAHANQVYRQILETTDNGIANN-----T--.DIFKTTDSNGDLIFTAS.............E........I........HGYSNVQVSGFLSVWAPKDAADDQDVRTTASES.TS.ND.GN.TLHSNAALDSNLIYE.GFSNFQSTPQ..SESEFANVKIAANVNLFKSWGVTSFQMAPQYRSSTDT.....S.FLDSIIQNGYAFT.D..RYDL...G.....F.......E.T......P.....TK..YGTDQQLRDAIKALHANGIQAMADFVPDQIYNLPQTELVSVSRTDSLGN....Q..SANSNAANVL...YVSHTVGGGE-YQSKYGGEFLALIKSKYPSLFKTI..................QVST.G............LPIDDSTKIKEWSAKYFNGSNIQGRGFGYVLSD.GGTQNYFKVISnSTD.DDFLPNQLT.GQPTTTGFEQT--sk...............................................
B1N0B6_LEUCK/312-1112                 ...................................................LLMAWWPDKSTQVTYLNYMKDQGL.L.SG.........THhFSDNENMRTLTAAAMQAQVNIEKKIGQLGNTDWLKTAM.......TQYIDAQPNWNIDSEA..........KGDD...HLQGGALLYTN..SD.....MSPKANS.DYRKLSRTPKNQKGQIADKYKQ..--..-GGFELLLANDVDNSNPVVQAEQLNWLHYMMNIGSILQNDDQANFDGYRVDAVDNVDADLLQIAGEYAKAAYGVDKNDARANQHLSILEDWGDEDPDYVKAHGNQQITMDFPLHLAIKYALNM.....................PNDKRS.G.LEPTRE..H.S..LV.KRITDDKENVAQPNYSFIRAHDSE...VQTIIADI..IKDKIN......PVSTGLdsT..VTLDQIKQAFDIYNADELKAD..KVYTPYNIPASYALLLTNKDTIPRVYYGDMFTDDGQYMAKQSPYYQAIDALLKARIKYAAGGQTMKM.......nYFP.D.EQ.................SVMTSVRYGKGAMTA....SD.SGNQ.E.TR.YQGIGLVVNNRPDLKLSDKDEVKMDMGAAHKNQDYRPVLLTTKSGLKVYSTDANAP-.--VVRTDANGQLTFKAD.............M........V........YGVNDPQVSGYIAAWVPVGASENQDARTKSETT.QS.TD.GS.VYHSNAALDSQVIYE.GFSNFQDFPT..TPDEFTNIKIAQNVNLFKDWGITSFEMAPQYRASSDK.....S.FLDAIVQNGYAFT.D..RYDI...G.....Y.......N.T......P.....TK..YGTADNLLDALRALHGQGIQAINDWVPDQIYNLPDEQLVTAIRTDGSGD....H..TYGSVIDHTL...YASKTVGGGI-YQQQYGGAFLDQLKTQYPQLFQQK..................QIST.D............QPMNPDIQIKSWEAKYFNGSNIQGRGAWYVLKD.WGTQQYFNVS-.-DA.QTFLPKQLL.GEKAKTGFVTRG-k................................................
B1MWP4_LEUCK/349-1147                 ...................................................IVSVWWPSKQTQVNYLNYMSQMGL.I.DN.........RQmFSLKDNQAMLNIACTTVQQAIETKIGVANSTAWLKTAI.......DDFIRTQPQWNMSSED..........PKND...HLQNGALTFVN..SP.....LTPDTNS.NFRLLNRTPTNQTGV--PKYTI.dQS..KGGFELLLANDVDNSNPVVQAEQLNWLHYLMNFGSITANDSAANFDGIRVDAVDNVDADLLQIAADYFKAAYGVDKNDATANQHLSILEDWSHNDPEYVKDFGNNQLTMDDYMHTQLIWSLTK.....................DMRMRG.T.MQRFMD..Y.Y..LV.NRNHDSTENTAIPNYSFVRAHDSE...VQTVIAQI..ISELHP......DVKNSL..A..PTADQLAEAFKIYNNDEKQAD..KKYTQYNMPSAYAMLLTNKDTVPRVYYGDLYTDDGQYMANKSPYFDAINGLLKSRIKYVAGGQSMAV........---.D.QN.................DILTNVRYGKGAMSV....TD.SGNA.D.TR.TQGIGVIVSNKENLALKSGDTVTLHMGAAHKNQAFRLLLGTTADNLSYYDNDN-AP-.--VKYTNDQGDLIFDNT.............E........I........YGVRNPQVSGFLAVWVPVGADSHQDARTLSDDT.AH.HD.GK.TFHSNAALDSQVIYE.GFSNFQAFAT..NTEDYTNAVIAKNGQLFKDWGITSFQLAPQYRSSTDT.....S.FLDSIIQNGYAFT.D..RYDL...G.....Y.......G.T......P.....TK..YGTVDQLRDAIKALHANGIQAIADWVPDQIYNLPGQELATVTRTNSYGD....K..DTNSDIDQSL...YVIQSRGGGK-YQAQYGGAFLSDIQKKYPALFETK..................QIST.G............LPMDPSQKITEWSGKYFNGSNIQGKGAGYVLKD.SGTDQYYKVTSnNNN.RDFLPKQLT.DDLSETGFVRDN-i................................................
T0TFB4_9STRE/282-1087                 ...................................................LVMAWWPDVDTQVNYLNHMSEY-F.G.MG.........KK.YSATDKQSTLNVAAEAIQIKIEQEIARRGNAAWLREII.......ASFVATQDKWNMNSED..........RDTD...HLQGGALLYVN..SD.....LTEWANS.DYRLLNRAPTYQNGQ--TNYHK..AD.rTGGYDFLLANDVDNSNPVVQAEQLNQLYYLMNWGKVVFGDAEANFDGVRVDAVDNVDADLLQLYTDLFEAAYGVNKTEAQALAHISILEAWSFNDPDYNHDTNGAALAIDNGLRMAFLDVLTR.....................PEGSRS.N.LESLIH..N.DlgMT.DRTVDSAYGDTMPSYAFVRAHDSE...VQGIIASI..IAGQIN......PKTDGF..T..FTLEELQKAFEIYNADMNSVH..KKYTHFNIPAAYALLLTNMESVPRVYYGDLFTDNGQYMAVKSPYYNQIVALLKSRIKYAAGGQAMNVq......yPAG.A.NG.................GILTSVRFGKGIMTA....DQ.KATD.EsVP.TSGIVTIISNNPNLKLNGSDVIAVQVGIAHAGQYYRPLLSPTENGLQAYLNDSDT--.NITKLVDENGFIYFTGD.............E........I........KGFQTVDMNGFLTVWVPVGAAADQDIRVKPSTE.AK.EA.GKlTYETSAALDSQVIFE.GFSNFQDFVK..DPSQYTNKVIAENADLFASWGITSFELAPQYVSSTDG.....T.FLDSIIQNGYAFS.D..RYDL...A.....M.......S.K......N.....NK..YGSAEDLRNAIKALHKRGIQVIADWVPDQIYALPGEEIVTATRVNDYGE....E..REGAQIKNKP...YAANTKSSGKDYQAQYGGEFLDYLQKTYPSIFERV..................MISN.G............QKIDPSTKIKVWKAEYFNGTNILGKGSDYVLND.QATGTYFTVT-.-EN.GAFLPKQMT.SDDAKTGFYYDGK.................................................
B1MZT7_LEUCK/361-1027                 ...................................................LLMSWWPDKNTQVAYLQYMQSVGM.L.PD.........DVkVSNDDNMSTLTDAAMTVQKNIESRIGVSGKTDWLKQDM.......NKLIDSQANWNIDSES..........KGND...HLQGGALLYVN..DD.....KTPNANS.DYRLLNRTPTNQTGQ---ITDP..SK..QGGYEMLLANDVDNSNPVVQAEQLNWLHYMMNIGTIAQNDPTANFDGYRVDAVDNVDADLLQIAGDYFKAAYGTGKTEVNANNHISILEDWDNNDSAYIKAHGNNQLTMDFPAHLALKYALNM.....................PLAAQS.G.LEPLIN..T.S..LV.KRGKDATENEAQPNYAFIRAHDSE...VQTVIAQI..IKDKIN......TKSDGL..T..VTPDEIKQAFNIYNADELKAD..KEYTAYNIPASYAVLLTNKDTVPRVYYGDLFSDDGQYMSQKSPYYDAITSLLKSRIKYVAGGQSMNM........TYL.H.ECfdpak......netkpqGVLTSVRYGKGAMTA....DD.LGNS.D.TR.QQGIGLVINNKPFLNLNDDEQIVLNMGAAHKNQAYRPLMLTTKSGLQIYDKDAGAP-.--VVYTNDAGQLIFKSD.............M........V........YGVSNPQVSGYFAAWVPVGASDSQDARTQSSQS.ET.KD.GD.VYHSNAALDSNVIYE.GFSNFQAMPE..KNDDFTNVKIAQNAKLFKDLGITSFELAPQYRSSTDN.....S.FLDSVIQNGYAFT.D..RYDV...G.....Y.......N.T......P.....TK..YGTVDQLLDSLRALHAQGIQAIND-------------------------....-..----------...-----------------------------------..................----.-............---------------------------------.-----------.---.---------.-------------.................................................
Q03VD8_LEUMM/370-1169                 ...................................................ILSVWWPDKNTQVNYLNYMADLGF.I.SN.........ADsFETGDSQSLLNEASNYVQKSIEMKISAQQSTEWLKDAM.......AAFIVTQPQWNETSED..........MSND...HLQNGALTYVN..SP.....LTPDANS.NFRLLNRTPTNQTGEQAYNLDN..S-..KGGFELLLANDVDNSNPVVQAEQLNWLYYLMNFGTITANDADANFDGIRVDAVDNVDADLLQIAADYFKLAYGVDQNDATANQHLSILEDWSHNDPLYVTDQGSNQLTMDDYVHTQLIWSLTK.....................SSDIRG.T.MQRFVD..Y.Y..MV.DRSNDSTENEAIPNYSFVRAHDSE...VQTVIAQI..VSDLYP......DVENSL..A..PTTEQLAAAFKVYNEDEKLAD..KKYTQYNMASAYAMLLTNKDTVPRVYYGDLYTDDGQYMATKSPYYDAINTLLKARVQYVAGGQSMSV........---.D.SN.................DVLTSVRYGKDAMTA....SD.TGTS.E.TR.TEGVGVIVSNNAELQLEDGHTVTLHMGAAHKNQAYRALLSTTADGLAYYDTDENAP-.--VAYTDANGDLIFTNE.............S........I........YGVQNPQVSGYLAVWVPVGAQQDQDARTASDTT.TN.TS.DK.VFHSNAALDSQVIYE.GFSNFQAFAT..DSSEYTNVVIAQNADQFKQWGVTSFQLAPQYRSSTDT.....S.FLDSIIQNGYAFT.D..RYDL...G.....Y.......G.T......P.....TK..YGTADQLRDAIKALHASGIQAIADWVPDQIYNLPEQELATVTRTNSFGD....D..DTDSDIDNAL...YVVQSRGGGQ-YQEMYGGAFLEELQALYPSLFKVN..................QIST.G............VPIDGSVKITEWAAKYFNGSNIQGKGAGYVLKD.MGSNKYFKVVSnTED.GDYLPKQLT.NDLSETGFTHDDK.................................................
#=GC SS_cons                          ...................................................HHHHHTSSHHHHHHHHHHHHTSGG.S.GG.........S-.EEE-SS-GGGGGG--S---TT--TTTTTSS--TT--SS.......--SSEEE-TTSHHHHH..........THHH...S-GGG---EEE.TTG.....HHHHHHH.HHHHHH-TTTBHHHHHTT--EE.--S..HHHHHHHTTSSSBEE-HHHHHHHHHHTTS-GGG---STHHHHSSSS-TSEE--SSESS-EEE-S--SSTTTHHHHHHHHHHHT-TT--TT---HHHHHHHHHHHHHHHH-SS-SSS-S-HHHH.....................SSSSTT.S.-TTHHH..H.H..HH.H--S-EEEEEEEETTEEEEEEEE-...BSSTT---..HHHT--......S-TT-B..T..EEEEE--GGGTT-EEEEEEEE..SSEEE--STGGGGGG-EE--TTSEEEEETTT-B-EESSS-EEEEEEEEETT--TT---------SB-........SHH.H.-E.................SHHHHHHHTHHHHHH....EE.----.-.--.-SSHHHHTT-SSSBS-TT-SSSSS-BTTB-HHHHHHHHHHHHHTT-EEEEEE--S-E.--SEEEEEEEEEE-TTS.............E........S........THHHHHHH-HHHHHSB-TTTSSB--TTS--SS-.GG.EE.EE.-SS-TT-B-EETTTT.E-BEETTSEB..HHHH--XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.....X.XXXXXXXXXXXXX.X..XXXX...X.....X.......X.X......X.....XX..XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX....X..XXXXXXXXXX...XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX..................XXXX.X............XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX.XXXXXXXXXX-.-XX.XXXXXXXXX.XXXXXX-------XXXXXXXXXXXX.....................................
#=GC seq_cons                         ...................................................lLhsWWPsppTQssYlNaMpp.hh.h.ps.........s..asttssp.pLs.AupslQhtIEp+IutptsTpWL+phh.......stFlpoQspWNhsSEp...........tsD...HLQGGALhasN..os.....hTs.ANS.saRLLNRTPTpQsGp...ph....s....GGaEhLLANDVDNSNPlVQAEQLNWLaYLMNaGsIstsDssANFDulRVDAVDNVDADLLQlts-YhKssYsssps-tsA.pHlSILEsWstNDstYhcspssspLshDshh+hslhhuLsp.....................s.s.Ru.s.hpshhs..t.t..ls.sRss-sspsps.PsYoFlRAHDSE...VQslIupI..Ippths......stssuh..s..hTh-plppAFcIYNtD.hpss..KcYTpYNlPuuYAhlLTNKDolPRVYYGDhYTDDGQYMupKosYYDAIssLL+uRlKYVuGGQsMth............s.ps.................slLTSVRYGKsshsu....sD.pGsp.p.TR.TpGlullluNpPsLpLsts-plslpMGtAHtNQtYRsllLoTpsGlt.Y.sDtps.....hthTsspGpLhFsss.............-........l........hGhtNspVSGYLuVWVPVGAsssQDsRstuoss.ts.sD.Gp.sh+osAALDSpVIYE.GFSNFQshss..ppspaTNhhIApNsslFppWGlTsFEhAPQYhSSsDs.....o.FLDSlIpNGYAFT.D..RYDL...G.....h.......s.p......s.....sK..YGoscpLhsAl+ALHssGIpshADWVPDQhYsLPspElVTsoRssphGp........tsu.lsppL...YsspTpuuGp.YQtpYGGtFLscLptpYPpLFppp..................pIST.G.............shDss.KIppWSAKYFNGoNI.G+GshYVLpD..uospYFpls...ps.tsaLPppLh.sp.stTGh......................................................
//
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