GenomeNet

Database: Pfam
Entry: HDAC4_Gln
LinkDB: HDAC4_Gln
Original site: HDAC4_Gln 
#=GF ID   HDAC4_Gln
#=GF AC   PF12203.7
#=GF DE   Glutamine rich N terminal domain of histone deacetylase 4
#=GF AU   Mistry J, Gavin OL
#=GF SE   pdb_2o94
#=GF GA   25.00 25.00;
#=GF TC   25.10 25.10;
#=GF NC   24.40 24.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   17360518
#=GF RT   Crystal structure of a conserved N-terminal domain of histone
#=GF RT   deacetylase 4 reveals functional insights into glutamine-rich
#=GF RT   domains.
#=GF RA   Guo L, Han A, Bates DL, Cao J, Chen L;
#=GF RL   Proc Natl Acad Sci U S A. 2007;104:4297-4302.
#=GF DR   INTERPRO; IPR024643;
#=GF CC   This domain is found in eukaryotes, and is approximately 90
#=GF CC   amino acids in length. The family is found in association with
#=GF CC   Pfam:PF00850. The domain forms an alpha helix which complexes to
#=GF CC   form a tetramer. The glutamine rich domains have many intra- and
#=GF CC   inter-helical interactions which are thought to be involved in
#=GF CC   reversible assembly and disassembly of proteins. The domain is
#=GF CC   part of histone deacetylase 4 (HDAC4) which removes acetyl
#=GF CC   groups from histones. This restores their positive charge to
#=GF CC   allow stronger DNA binding thus restricting transcriptional
#=GF CC   activity.
#=GF SQ   317
#=GS R7VQN6_COLLI/56-145       AC R7VQN6.1
#=GS A0A093IRC8_EURHL/1-39     AC A0A093IRC8.1
#=GS W5LGA0_ASTMX/1-39         AC W5LGA0.1
#=GS A0A0G2K082_RAT/37-127     AC A0A0G2K082.1
#=GS B7ZDF6_MOUSE/58-146       AC B7ZDF6.1
#=GS F6XPY2_CALJA/34-124       AC F6XPY2.1
#=GS A0A091Q815_HALAL/31-120   AC A0A091Q815.1
#=GS W5MRU6_LEPOC/34-124       AC W5MRU6.1
#=GS A0A091MBY9_CARIC/34-124   AC A0A091MBY9.1
#=GS A0A091IW22_9AVES/36-125   AC A0A091IW22.1
#=GS A0A093IKX5_PICPB/31-120   AC A0A093IKX5.1
#=GS E9QIJ9_DANRE/67-157       AC E9QIJ9.6
#=GS A0A094L723_9AVES/56-145   AC A0A094L723.1
#=GS H0V5J1_CAVPO/37-127       AC H0V5J1.1
#=GS V8P9U6_OPHHA/6-95         AC V8P9U6.1
#=GS F6SZ92_HORSE/38-128       AC F6SZ92.1
#=GS F1NP26_CHICK/35-125       AC F1NP26.2
#=GS G3U3T8_LOXAF/62-159       AC G3U3T8.1
#=GS H3D919_TETNG/28-116       AC H3D919.1
#=GS H0VMW7_CAVPO/62-152       AC H0VMW7.1
#=GS F1P6I3_CANLF/68-156       AC F1P6I3.2
#=GS G1R0J0_NOMLE/68-165       AC G1R0J0.1
#=GS G3NZC1_GASAC/33-121       AC G3NZC1.1
#=GS A0A099YS05_TINGU/31-121   AC A0A099YS05.1
#=GS E0VLQ7_PEDHC/24-120       AC E0VLQ7.1
#=GS H2MV37_ORYLA/48-137       AC H2MV37.1
#=GS E1C7C0_CHICK/116-206      AC E1C7C0.2
#=GS A0A151PBT9_ALLMI/42-122   AC A0A151PBT9.1
#=GS A0A087YGA8_POEFO/113-201  AC A0A087YGA8.2
#=GS A0A1B0GSQ5_MOUSE/37-127   AC A0A1B0GSQ5.1
#=GS A0A087QJ17_APTFO/31-120   AC A0A087QJ17.1
#=GS H2TZG1_TAKRU/20-108       AC H2TZG1.1
#=GS S9YY75_CAMFR/86-174       AC S9YY75.1
#=GS W5PAD5_SHEEP/112-201      AC W5PAD5.1
#=GS E7FH14_DANRE/50-138       AC E7FH14.1
#=GS A0A091QGZ6_9GRUI/34-124   AC A0A091QGZ6.1
#=GS M3WPZ1_FELCA/6-96         AC M3WPZ1.1
#=GS G1P7E4_MYOLU/32-122       AC G1P7E4.1
#=GS G3S8P2_GORGO/37-127       AC G3S8P2.1
#=GS A0A091GZW5_BUCRH/31-120   AC A0A091GZW5.1
#=GS I3JGK7_ORENI/71-159       AC I3JGK7.1
#=GS U3IQJ6_ANAPL/31-121       AC U3IQJ6.1
#=GS A0A091Q513_LEPDC/34-124   AC A0A091Q513.1
#=GS F7ACM8_ORNAN/35-91        AC F7ACM8.1
#=GS K7G4D8_PELSI/36-81        AC K7G4D8.1
#=GS A0A091K2F0_COLST/34-124   AC A0A091K2F0.1
#=GS HDAC5_PONAB/67-164        AC Q5R902.1
#=GS W5JYJ6_ASTMX/53-141       AC W5JYJ6.1
#=GS H2TZF8_TAKRU/35-123       AC H2TZF8.1
#=GS A0A093BLR2_CHAPE/56-145   AC A0A093BLR2.1
#=GS S9WMZ0_CAMFR/6-83         AC S9WMZ0.1
#=GS H2MR85_ORYLA/19-107       AC H2MR85.1
#=GS A0A091V5G9_OPIHO/31-120   AC A0A091V5G9.1
#=GS B7ZDF5_MOUSE/86-174       AC B7ZDF5.1
#=GS J9P9N5_CANLF/41-129       AC J9P9N5.1
#=GS F6PUT1_CALJA/68-165       AC F6PUT1.1
#=GS A0A091PFX6_APAVI/34-124   AC A0A091PFX6.1
#=GS H3AFL1_LATCH/62-152       AC H3AFL1.1
#=GS H2QU82_PANTR/37-127       AC H2QU82.1
#=GS S9WA61_CAMFR/267-362      AC S9WA61.1
#=GS H3B8Y6_LATCH/41-129       AC H3B8Y6.1
#=GS A0A087X875_POEFO/74-162   AC A0A087X875.1
#=GS F7BD61_XENTR/37-129       AC F7BD61.1
#=GS F6QMU7_BOVIN/67-155       AC F6QMU7.1
#=GS G3HD66_CRIGR/22-112       AC G3HD66.1
#=GS HDAC5_HUMAN/67-164        AC Q9UQL6.2
#=GS A0A091J4F9_9AVES/34-124   AC A0A091J4F9.1
#=GS A0A091SXW2_9AVES/32-121   AC A0A091SXW2.1
#=GS H2TZG2_TAKRU/20-108       AC H2TZG2.1
#=GS H0X2U2_OTOGA/67-164       AC H0X2U2.1
#=GS S9X6B2_CAMFR/267-359      AC S9X6B2.1
#=GS H2LSQ0_ORYLA/37-120       AC H2LSQ0.1
#=GS M4A0P4_XIPMA/35-125       AC M4A0P4.1
#=GS H2UG30_TAKRU/62-152       AC H2UG30.1
#=GS G3WQM8_SARHA/68-156       AC G3WQM8.1
#=GS A0A091RSW4_NESNO/34-124   AC A0A091RSW4.1
#=GS F6X8E7_CANLF/37-127       AC F6X8E7.1
#=GS G5BZI9_HETGA/31-121       AC G5BZI9.1
#=GS G3NNN9_GASAC/68-139       AC G3NNN9.1
#=GS I3J9U5_ORENI/86-175       AC I3J9U5.1
#=GS G3UF87_LOXAF/71-104       AC G3UF87.1
#=GS C9J835_HUMAN/6-70         AC C9J835.8
#=GS M3YR88_MUSPF/37-127       AC M3YR88.1
#=GS A0A091PST2_HALAL/34-124   AC A0A091PST2.1
#=GS G3HLJ3_CRIGR/68-156       AC G3HLJ3.1
#=GS G3U951_LOXAF/86-174       AC G3U951.1
#=GS L5KRT3_PTEAL/86-143       AC L5KRT3.1
#=GS A0A091WY96_OPIHO/34-124   AC A0A091WY96.1
#=GS M3ZIQ0_XIPMA/37-127       AC M3ZIQ0.1
#=GS Q3UJF1_MOUSE/68-156       AC Q3UJF1.1
#=GS I3MGR1_ICTTR/35-125       AC I3MGR1.1
#=GS B7ZDF4_MOUSE/26-114       AC B7ZDF4.1
#=GS A0A093JE36_FULGA/34-124   AC A0A093JE36.1
#=GS L9KKK2_TUPCH/35-125       AC L9KKK2.1
#=GS F6Z8Z9_HORSE/37-127       AC F6Z8Z9.1
#=GS F1PRU6_CANLF/62-152       AC F1PRU6.2
#=GS M7C334_CHEMY/54-122       AC M7C334.1
#=GS F6X4A5_XENTR/70-158       AC F6X4A5.1
#=GS A0A091SBP1_NESNO/31-120   AC A0A091SBP1.1
#=GS X1WED5_DANRE/43-129       AC X1WED5.1
#=GS A0A151MQF3_ALLMI/37-127   AC A0A151MQF3.1
#=GS H2UTM8_TAKRU/66-165       AC H2UTM8.1
#=GS A0A091HZS3_CALAN/56-145   AC A0A091HZS3.1
#=GS G3HYN8_CRIGR/1-35         AC G3HYN8.1
#=GS C9J0X4_HUMAN/35-123       AC C9J0X4.1
#=GS H2SKG7_TAKRU/36-126       AC H2SKG7.1
#=GS V8PHC6_OPHHA/86-174       AC V8PHC6.1
#=GS F6ZE39_HORSE/37-124       AC F6ZE39.1
#=GS A0A151N9L2_ALLMI/58-148   AC A0A151N9L2.1
#=GS G3RTK4_GORGO/65-145       AC G3RTK4.1
#=GS M3WKB8_FELCA/1-68         AC M3WKB8.1
#=GS A0A091MPW1_9PASS/34-124   AC A0A091MPW1.1
#=GS A0A087VR57_BALRE/31-120   AC A0A087VR57.1
#=GS I3LYS2_ICTTR/37-124       AC I3LYS2.1
#=GS A0A087WSF0_MOUSE/61-112   AC A0A087WSF0.1
#=GS F7BC62_MONDO/91-181       AC F7BC62.2
#=GS A0A091KJY6_9GRUI/34-124   AC A0A091KJY6.1
#=GS A0A096NFQ1_PAPAN/37-127   AC A0A096NFQ1.1
#=GS A0A0P7UZA5_9TELE/354-456  AC A0A0P7UZA5.1
#=GS A0A093R0D1_PHACA/34-124   AC A0A093R0D1.1
#=GS A0A091TH64_PHALP/34-124   AC A0A091TH64.1
#=GS A0A087TSP5_9ARAC/33-139   AC A0A087TSP5.1
#=GS A0A091UVB5_NIPNI/34-124   AC A0A091UVB5.1
#=GS A0A1B0GR65_MOUSE/37-127   AC A0A1B0GR65.1
#=GS A0A0P7XBI1_9TELE/62-152   AC A0A0P7XBI1.1
#=GS A0A093HK13_STRCA/56-145   AC A0A093HK13.1
#=GS F1QUC5_DANRE/67-157       AC F1QUC5.1
#=GS M3XM23_MUSPF/62-152       AC M3XM23.1
#=GS W5LGJ9_ASTMX/41-131       AC W5LGJ9.1
#=GS H2TZG5_TAKRU/1-89         AC H2TZG5.1
#=GS F6U8V5_CALJA/6-96         AC F6U8V5.1
#=GS A0A091USF6_NIPNI/56-145   AC A0A091USF6.1
#=GS G5BN73_HETGA/419-507      AC G5BN73.1
#=GS H2TZG0_TAKRU/20-105       AC H2TZG0.1
#=GS F1MWS5_BOVIN/37-124       AC F1MWS5.2
#=GS A0A0L8IA03_OCTBM/40-128   AC A0A0L8IA03.1
#=GS A0A0D9RM59_CHLSB/37-127   AC A0A0D9RM59.1
#=GS G1PQF2_MYOLU/33-123       AC G1PQF2.1
#=GS G1MJ38_AILME/68-152       AC G1MJ38.1
#=GS I3MXF0_ICTTR/68-159       AC I3MXF0.1
#=GS C9J481_HUMAN/31-121       AC C9J481.1
#=GS M3YDP5_MUSPF/40-128       AC M3YDP5.1
#=GS H2SKG8_TAKRU/2-43         AC H2SKG8.1
#=GS B7Z3P7_HUMAN/37-127       AC B7Z3P7.1
#=GS L9KKS0_TUPCH/314-404      AC L9KKS0.1
#=GS H0VUA3_CAVPO/67-98        AC H0VUA3.1
#=GS F6VAE2_MACMU/32-119       AC F6VAE2.1
#=GS G1NCZ1_MELGA/34-124       AC G1NCZ1.1
#=GS A0A093HP20_STRCA/31-120   AC A0A093HP20.1
#=GS A0A093CC50_9AVES/56-145   AC A0A093CC50.1
#=GS L8Y465_TUPCH/86-150       AC L8Y465.1
#=GS A0A151NA80_ALLMI/58-148   AC A0A151NA80.1
#=GS A0A099Z045_TINGU/32-125   AC A0A099Z045.1
#=GS H2QJQ3_PANTR/62-152       AC H2QJQ3.1
#=GS B5MCF1_HUMAN/65-155       AC B5MCF1.2
#=GS G3RCU7_GORGO/37-124       AC G3RCU7.1
#=GS A0A091NIY7_APAVI/56-145   AC A0A091NIY7.1
#=GS F7GQ46_CALJA/66-136       AC F7GQ46.1
#=GS HDAC9_HUMAN/37-124        AC Q9UKV0.2
#=GS H2TZF9_TAKRU/28-125       AC H2TZF9.1
#=GS H2UTN0_TAKRU/33-132       AC H2UTN0.1
#=GS A0A091F7B1_CORBR/32-121   AC A0A091F7B1.1
#=GS H0WQY7_OTOGA/1-90         AC H0WQY7.1
#=GS F6XSP9_CALJA/62-152       AC F6XSP9.1
#=GS A0A093J0Z4_EURHL/34-121   AC A0A093J0Z4.1
#=GS A0A0D9S118_CHLSB/68-125   AC A0A0D9S118.1
#=GS F1QRR4_DANRE/32-122       AC F1QRR4.1
#=GS F1MYR0_BOVIN/62-152       AC F1MYR0.2
#=GS G3PNP4_GASAC/48-127       AC G3PNP4.1
#=GS A0A096MQP8_PAPAN/37-124   AC A0A096MQP8.1
#=GS HDAC5_MOUSE/67-155        AC Q9Z2V6.2
#=GS G3REJ7_GORGO/35-125       AC G3REJ7.1
#=GS G1KCW7_ANOCA/69-157       AC G1KCW7.2
#=GS G3NC45_GASAC/41-128       AC G3NC45.1
#=GS A0A0F8ADF1_LARCR/66-160   AC A0A0F8ADF1.1
#=GS H0YWN9_TAEGU/2-92         AC H0YWN9.1
#=GS G3TEN3_LOXAF/37-126       AC G3TEN3.1
#=GS H2NTV4_PONAB/68-153       AC H2NTV4.1
#=GS M4ASQ7_XIPMA/33-121       AC M4ASQ7.1
#=GS G5BHI3_HETGA/56-146       AC G5BHI3.1
#=GS G1T7F7_RABIT/37-127       AC G1T7F7.2
#=GS H3BVX6_TETNG/65-154       AC H3BVX6.1
#=GS A0A1B0GS15_MOUSE/37-124   AC A0A1B0GS15.1
#=GS A0A151PCS7_ALLMI/66-146   AC A0A151PCS7.1
#=GS G7P0S6_MACFA/37-127       AC G7P0S6.1
#=GS G1LPL4_AILME/37-127       AC G1LPL4.1
#=GS F7IJK3_CALJA/35-137       AC F7IJK3.1
#=GS S7PSN1_MYOBR/82-172       AC S7PSN1.1
#=GS H0YYG0_TAEGU/61-151       AC H0YYG0.1
#=GS HDAC4_HUMAN/62-152        AC P56524.3
#=GS HDAC4_HUMAN/62-152        DR PDB; 2O94 B; 62-129;
#=GS HDAC4_HUMAN/62-152        DR PDB; 2H8N A; 62-129;
#=GS HDAC4_HUMAN/62-152        DR PDB; 2O94 A; 62-129;
#=GS HDAC4_HUMAN/62-152        DR PDB; 2H8N B; 62-129;
#=GS HDAC4_HUMAN/62-152        DR PDB; 2O94 D; 62-129;
#=GS HDAC4_HUMAN/62-152        DR PDB; 2H8N C; 62-129;
#=GS HDAC4_HUMAN/62-152        DR PDB; 2O94 C; 62-129;
#=GS HDAC4_HUMAN/62-152        DR PDB; 2H8N D; 62-129;
#=GS G3SFB9_GORGO/62-152       AC G3SFB9.1
#=GS F7GZK7_MACMU/67-164       AC F7GZK7.1
#=GS U3I9T4_ANAPL/30-121       AC U3I9T4.1
#=GS C3Z354_BRAFL/13-98        AC C3Z354.1
#=GS A0A096LZC9_POEFO/51-139   AC A0A096LZC9.1
#=GS I3IX83_ORENI/31-121       AC I3IX83.1
#=GS F6SA28_CALJA/37-124       AC F6SA28.1
#=GS I3JGK8_ORENI/33-121       AC I3JGK8.1
#=GS A0A093CLF0_TAUER/31-121   AC A0A093CLF0.1
#=GS H2TZG3_TAKRU/20-108       AC H2TZG3.1
#=GS F1MNA5_BOVIN/67-164       AC F1MNA5.2
#=GS G1KLX7_ANOCA/37-126       AC G1KLX7.1
#=GS H3CSB1_TETNG/36-125       AC H3CSB1.1
#=GS F1SEI3_PIG/37-127         AC F1SEI3.2
#=GS A0A087R7E5_APTFO/34-124   AC A0A087R7E5.1
#=GS HDA9B_DANRE/37-127        AC Q6PBI4.1
#=GS H3B734_LATCH/35-125       AC H3B734.1
#=GS G3T6K8_LOXAF/34-120       AC G3T6K8.1
#=GS A0A0A0A704_CHAVO/31-121   AC A0A0A0A704.1
#=GS G3PNP0_GASAC/71-148       AC G3PNP0.1
#=GS I3LM52_PIG/32-122         AC I3LM52.1
#=GS A0A151MQE7_ALLMI/37-127   AC A0A151MQE7.1
#=GS F6ZVK4_ORNAN/37-127       AC F6ZVK4.2
#=GS A0A0R4IAH0_DANRE/61-151   AC A0A0R4IAH0.1
#=GS I3IX82_ORENI/84-174       AC I3IX82.1
#=GS M3VY28_FELCA/67-155       AC M3VY28.1
#=GS C9J1W4_HUMAN/37-127       AC C9J1W4.1
#=GS HDAC9_MOUSE/37-124        AC Q99N13.2
#=GS A0A087XDC8_POEFO/45-135   AC A0A087XDC8.2
#=GS H2QD60_PANTR/67-164       AC H2QD60.1
#=GS A0A091D6P9_FUKDA/114-204  AC A0A091D6P9.1
#=GS A0A093GA44_PICPB/34-124   AC A0A093GA44.1
#=GS G3UV76_MELGA/37-124       AC G3UV76.1
#=GS M7BEH0_CHEMY/16-103       AC M7BEH0.1
#=GS C9IZS0_HUMAN/37-127       AC C9IZS0.2
#=GS G1S3X8_NOMLE/37-127       AC G1S3X8.1
#=GS A0A093BY19_TAUER/56-145   AC A0A093BY19.1
#=GS H3DM61_TETNG/37-122       AC H3DM61.1
#=GS U3K5G0_FICAL/37-127       AC U3K5G0.1
#=GS A0A091INB1_CALAN/31-121   AC A0A091INB1.1
#=GS H2UG33_TAKRU/3-104        AC H2UG33.1
#=GS A0A0P7VKZ6_9TELE/46-134   AC A0A0P7VKZ6.1
#=GS A0A093ER24_TYTAL/34-124   AC A0A093ER24.1
#=GS A0A151MQF1_ALLMI/37-127   AC A0A151MQF1.1
#=GS F6ZBF4_ORNAN/62-152       AC F6ZBF4.1
#=GS H2UG34_TAKRU/15-63        AC H2UG34.1
#=GS A0A093QVU2_PHACA/56-145   AC A0A093QVU2.1
#=GS H2PMR0_PONAB/37-124       AC H2PMR0.1
#=GS K7GKY8_PIG/30-117         AC K7GKY8.1
#=GS G7PKF6_MACFA/62-152       AC G7PKF6.1
#=GS L5KMM5_PTEAL/64-154       AC L5KMM5.1
#=GS A0A0Q3M9N3_AMAAE/4-46     AC A0A0Q3M9N3.1
#=GS A0A1B0GSB5_MOUSE/6-96     AC A0A1B0GSB5.1
#=GS F7HLM2_CALJA/57-147       AC F7HLM2.1
#=GS A0A093QS59_9PASS/56-145   AC A0A093QS59.1
#=GS F7H3I3_CALJA/37-127       AC F7H3I3.1
#=GS S7P4E9_MYOBR/67-157       AC S7P4E9.1
#=GS A0A091L9T6_CATAU/34-124   AC A0A091L9T6.1
#=GS A0A099ZX46_CHAVO/56-145   AC A0A099ZX46.1
#=GS F6VW34_MACMU/61-151       AC F6VW34.1
#=GS A0A1B0GSN4_MOUSE/37-114   AC A0A1B0GSN4.1
#=GS T1JB29_STRMM/58-149       AC T1JB29.1
#=GS A2AWS5_MOUSE/68-156       AC A2AWS5.1
#=GS F7GZL0_MACMU/67-164       AC F7GZL0.1
#=GS H2QD61_PANTR/68-165       AC H2QD61.1
#=GS A0A091CZ58_FUKDA/72-162   AC A0A091CZ58.1
#=GS L5KSG9_PTEAL/77-167       AC L5KSG9.1
#=GS A0A087VDU3_BALRE/30-120   AC A0A087VDU3.1
#=GS H2SKG6_TAKRU/40-131       AC H2SKG6.1
#=GS A0A0D9R125_CHLSB/62-152   AC A0A0D9R125.1
#=GS A0A087XQ10_POEFO/66-167   AC A0A087XQ10.2
#=GS F6TPS9_XENTR/62-152       AC F6TPS9.1
#=GS H3DQM5_TETNG/64-154       AC H3DQM5.1
#=GS A0A1B0GRH0_MOUSE/37-124   AC A0A1B0GRH0.1
#=GS W5PIS5_SHEEP/37-124       AC W5PIS5.1
#=GS A0A094LGU5_ANTCR/31-121   AC A0A094LGU5.1
#=GS G1KJ78_ANOCA/62-152       AC G1KJ78.2
#=GS A0A1B0GT67_MOUSE/58-148   AC A0A1B0GT67.1
#=GS G1LY09_AILME/62-152       AC G1LY09.1
#=GS G3R4Y7_GORGO/68-165       AC G3R4Y7.1
#=GS H2P937_PONAB/62-152       AC H2P937.1
#=GS F6VAF2_MACMU/37-124       AC F6VAF2.1
#=GS G1LY17_AILME/62-152       AC G1LY17.1
#=GS A0A0Q3PA29_AMAAE/103-193  AC A0A0Q3PA29.1
#=GS A0A151PC11_ALLMI/66-146   AC A0A151PC11.1
#=GS L5M2P1_MYODS/110-200      AC L5M2P1.1
#=GS F6X9B0_HORSE/61-149       AC F6X9B0.1
#=GS H3CU09_TETNG/64-154       AC H3CU09.1
#=GS G1SVG4_RABIT/69-157       AC G1SVG4.2
#=GS G1RSV2_NOMLE/62-152       AC G1RSV2.2
#=GS C9JD56_HUMAN/6-93         AC C9JD56.1
#=GS A0A1B0GSE4_MOUSE/37-124   AC A0A1B0GSE4.1
#=GS HDAC4_CHICK/62-151        AC P83038.1
#=GS E5RQ38_RAT/37-127         AC E5RQ38.1
#=GS A0A0R4J1F3_MOUSE/37-124   AC A0A0R4J1F3.1
#=GS S7P7V4_MYOBR/86-164       AC S7P7V4.1
#=GS H3B8Y5_LATCH/49-150       AC H3B8Y5.1
#=GS F6XQL9_CALJA/51-141       AC F6XQL9.1
#=GS W5N050_LEPOC/34-124       AC W5N050.1
#=GS M4AHC6_XIPMA/66-164       AC M4AHC6.1
#=GS H2UG32_TAKRU/19-109       AC H2UG32.1
#=GS A0A0F8B282_LARCR/60-148   AC A0A0F8B282.1
#=GS HDAC4_MOUSE/61-151        AC Q6NZM9.1
#=GS H0WX84_OTOGA/34-124       AC H0WX84.1
#=GS A0A131ZVL3_SARSC/173-267  AC A0A131ZVL3.1
#=GS G3UN27_LOXAF/37-123       AC G3UN27.1
#=GS F6VAD3_MACMU/37-127       AC F6VAD3.1
#=GS H2UG31_TAKRU/19-109       AC H2UG31.1
#=GS H2UTM9_TAKRU/37-136       AC H2UTM9.1
#=GS F1QUC6_DANRE/37-127       AC F1QUC6.2
#=GS K7FZ10_PELSI/34-124       AC K7FZ10.1
#=GS A0A091M0E7_CARIC/56-145   AC A0A091M0E7.1
#=GS B7ZDF7_MOUSE/67-155       AC B7ZDF7.1
#=GS F7G734_MONDO/68-156       AC F7G734.2
#=GS A0A151PCC1_ALLMI/65-145   AC A0A151PCC1.1
#=GS HDAC4_RAT/61-151          AC Q99P99.2
#=GS HDAC9_CHICK/37-127        AC Q5ZKH6.1
#=GS A0A091FKU3_9AVES/19-102   AC A0A091FKU3.1
#=GS A0A091KJU0_COLST/31-120   AC A0A091KJU0.1
#=GS W5L1S7_ASTMX/67-157       AC W5L1S7.1
#=GS U3JMK1_FICAL/27-72        AC U3JMK1.1
#=GS A0A093F5Y5_GAVST/34-124   AC A0A093F5Y5.1
#=GS K7GJR1_PELSI/62-152       AC K7GJR1.1
#=GS F6XF13_HORSE/62-150       AC F6XF13.1
#=GS A0A0F8C7W6_LARCR/104-194  AC A0A0F8C7W6.1
#=GS G1P6Y3_MYOLU/68-156       AC G1P6Y3.1
#=GS I3J443_ORENI/66-161       AC I3J443.1
R7VQN6_COLLI/56-145                  ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.-EMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
A0A093IRC8_EURHL/1-39                ................--------..-------------------------------------------.-Q............Q.QEMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
W5LGA0_ASTMX/1-39                    ................--------..-------------------------------------------.-H............Q.QELLA..........LKHQQELLE..HQR.KLERH...........RREQE.LEKQQREQKL...........................................
A0A0G2K082_RAT/37-127                ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
B7ZDF6_MOUSE/58-146                  ................MDPALREQ..QLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
F6XPY2_CALJA/34-124                  ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
A0A091Q815_HALAL/31-120              ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.-EMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
W5MRU6_LEPOC/34-124                  ................ADPSLREQ..QLQQELIALKQKQQIQRQLLIAEFQRQHEQLSRQHEAQLQEHV.KH............Q.QDMLA..........LKHQQELLE..HQR.KMEKH...........RHEQE.MEKHQREQKL...........................................
A0A091MBY9_CARIC/34-124              ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LERHRKEQQL...........................................
A0A091IW22_9AVES/36-125              ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.-EMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
A0A093IKX5_PICPB/31-120              ...............a-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.-EMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
E9QIJ9_DANRE/67-157                  ...............s-EVTVWER..QLQQELLLIQKQQQIQKQLLITEFQKQHENLVRQHQAQIQEHL.KL............Q.QELHV..........MKQQQEQLE..KER.KLELQ...........SQERE.LERHRREQQV...........................................
A0A094L723_9AVES/56-145              ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.-EMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
H0V5J1_CAVPO/37-127                  ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
V8P9U6_OPHHA/6-95                    ................MDPLMQEK..QLQQELILIQHQQQIQKQLLIAEFQKQHENLTRQHQAQIQEHM.KL............Q.KELLA..........IKYQQELLE..KEQ.KLEQQ...........RQEQE.LERHRREQ--c..........................................
F6SZ92_HORSE/38-128                  ...............t-EPTLREQ..QLQQELLALKQKQQLQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QELLA..........MKHQQELLE..HQR.KLERH...........RQEQE.LEKQHREQKL...........................................
F1NP26_CHICK/35-125                  ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
G3U3T8_LOXAF/62-159                  ................VDPALREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KVtega...vplqqQ.QEMLA..........AQRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
H3D919_TETNG/28-116                  ................VDTTMREQ..QLQQELVLLKQQQELQKQMLFAEFQKKHEVLTRQHEVQLQEHL.KQ............Q.QELLA..........AKRQQE-LE..QKR.KLEQQ...........RHE-E.QEKHRLEQQL...........................................
H0VMW7_CAVPO/62-152                  ...............a-EPALREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........LKHQQELLE..HQR.KLERH...........RQEQE.LEKQHREQKL...........................................
F1P6I3_CANLF/68-156                  ................VDPALREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQR.QQEQR...........RQE-E.LEKQRLEQQL...........................................
G1R0J0_NOMLE/68-165                  ................VDPTLREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLAakqq.qemlaAKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
G3NZC1_GASAC/33-121                  ................SDPGMWER..QLQQELLLIQKQQQIQKQLLISEFQKQHEKLTRQHQAQLQEHL.KL............Q.HELQA..........MKQQQELAE..KER.RLERN...........RREQH.V---------sslilrg....................................
A0A099YS05_TINGU/31-121              ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
E0VLQ7_PEDHC/24-120                  ...............g-DPGLHAQ..AFQQQLLQLKKQQQLQQQILLQHYQTQQQQLAEQHEQQLRHHL.KE...........fR.EQQKA..........LEEQKERRE..KEK.LEALK...........RKDKH.----------eqsavassevkqrlq............................
H2MV37_ORYLA/48-137                  ..............tp--PGHQEH..QLQHELVALKHKQQLQRQLLIAEFQRQHEQLSRQHEAQLQEHI.KH............Q.QDLLA..........LKHQQELLE..HHR.KMEQQ...........RHD-Q.LEKQQREQKL...........................................
E1C7C0_CHICK/116-206                 ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
A0A151PBT9_ALLMI/42-122              ................VDPTVREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHEHLTRQHEVQLQKHL.KE............K.SKESA..........IASTEVKLK..LQE.-----...........-----.----------fllskskepi.................................
A0A087YGA8_POEFO/113-201             ................VDTALREQ..QLQQELVLLKQQQELQKQLLFAEFQKKHEVLTRQHEVQLQEHL.KQ............Q.QELLA..........AKRQQE-LE..HKR.KLEQQ...........RHE-E.QEKQRLEQQL...........................................
A0A1B0GSQ5_MOUSE/37-127              ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
A0A087QJ17_APTFO/31-120              ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.-EMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
H2TZG1_TAKRU/20-108                  ................VDTAMREQ..QLQQELVLLKQQQELQKQMLFAEFQKKHEVLTRQHEVQLQEHL.KQ............Q.QELLA..........AKRQQE-LE..QKR.KLEQQ...........RHE-E.QEKHRLEQQL...........................................
S9YY75_CAMFR/86-174                  ................VDPALREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
W5PAD5_SHEEP/112-201                 ................VDPALREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KE............E.LEKQR..........LEQQLLILR..NKE.KSKES...........-----.----------aiastevklrlqef.............................
E7FH14_DANRE/50-138                  ................VDPSLREK..QLQHELLLLKQQQELQKQLLFAEFQKQHEVLTRQHEVQLQEHL.KQ............Q.QEILA..........AKRQQE-LE..QKR.KLEQQ...........RHE-E.MEKQRLEQQL...........................................
A0A091QGZ6_9GRUI/34-124              ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
M3WPZ1_FELCA/6-96                    ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
G1P7E4_MYOLU/32-122                  ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
G3S8P2_GORGO/37-127                  ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
A0A091GZW5_BUCRH/31-120              ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.-EMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
I3JGK7_ORENI/71-159                  ................VDTALREQ..QLQQELILLKQQQELQKQLLFAEFQKKHEVLTRQHEVQLQEHL.KQ............Q.QELLA..........AKRQQE-LE..QKR.KLEQQ...........RHE-E.QEKQRLEQQL...........................................
U3IQJ6_ANAPL/31-121                  ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
A0A091Q513_LEPDC/34-124              ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LEKHRREQQL...........................................
F7ACM8_ORNAN/35-91                   ................VDPALREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KV............-.-----..........---------..---.-----...........-----.----------gapa.......................................
K7G4D8_PELSI/36-81                   ................VDPAVREQ..QLQQELLVLQHEVQLQKHLKF----------------------.--............-.-----..........---------..---.-----...........-----.----------khsltsrremqppsgmk..........................
A0A091K2F0_COLST/34-124              ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
HDAC5_PONAB/67-164                   ................VDPTLREQ..LLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLAakqq.qemlaAKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
W5JYJ6_ASTMX/53-141                  ................MDPALREQ..QLQHELLLLKQQQELQKQLLFAEFQKQHEVLTRQHEVQLQEHL.KQ............Q.QELLA..........VKRQQE-LE..QKR.KLEQQ...........RHE-E.LEKQRLEQQL...........................................
H2TZF8_TAKRU/35-123                  ................VDTAMREQ..QLQQELVLLKQQQELQKQMLFAEFQKKHEVLTRQHEVQLQEHL.KQ............Q.QELLA..........AKRQQE-LE..QKR.KLEQQ...........RHE-E.QEKHRLEQQL...........................................
A0A093BLR2_CHAPE/56-145              ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.-EMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
S9WMZ0_CAMFR/6-83                    ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KV............A.DISLF..........LTSDSGSLH..H--.-----...........-----.----------nmgirgstr..................................
H2MR85_ORYLA/19-107                  ................VDTTLREQ..QLQQELVLLKQQQELQKQLLFAEFQKKHEVLTRQHEVQLQEHL.KQ............Q.QELLA..........AKRQQE-LE..QKR.KLEQQ...........RHE-E.QEKQRLEQQL...........................................
A0A091V5G9_OPIHO/31-120              ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHRQLSRQHEAQLHEHI.KQ............Q.-EMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
B7ZDF5_MOUSE/86-174                  ................MDPALREQ..QLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
J9P9N5_CANLF/41-129                  ................VDPALREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQR.QQEQR...........RQE-E.LEKQRLEQQL...........................................
F6PUT1_CALJA/68-165                  ................VDPTLREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLAakqq.qemlaAKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
A0A091PFX6_APAVI/34-124              ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
H3AFL1_LATCH/62-152                  ...............a-ESTLRDQ..QLQQELLALKQKQQVQRQLLIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QELLA..........MKHQQELME..HQR.KMEQH...........RQEQE.LEKQQREHKL...........................................
H2QU82_PANTR/37-127                  ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
S9WA61_CAMFR/267-362                 ...............a-EPALREQ..QLQQELLALKQKQQLQRQILIAEFQRQHEQLSRQHEAQLHEHI.KP............-.-----..........---------..---.-----...........-----.----------ladsilrsppgppappedtclghnavlieqlekrrggrerhlq
H3B8Y6_LATCH/41-129                  ................VDPLFREQ..QLQHELLILKQQQQMQKQLLFAEFQKQHEHLTRQHEVQLQEHI.KQ............Q.QEILA..........VKRQQE-LE..QQQ.KLEQQ...........RQE-E.LEKQRLEQQL...........................................
A0A087X875_POEFO/74-162              .............agr-----QDQ..HLQQELVALKHKQELQRQLLIAEFHRQHEQLSRQHEVQLQEHI.KH............Q.QDLLA..........LKHQQELLE..HHR.KMEQQ...........RHEQQ.LEKQQREQKL...........................................
F7BD61_XENTR/37-129                  ................VDPVLREK..QLQQELLIIKQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHL.KL............Q.QELLA..........MKHQQELLEreKEH.KMEQQ...........RKEQE.AERHRREQQL...........................................
F6QMU7_BOVIN/67-155                  ................VDPTLREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
G3HD66_CRIGR/22-112                  ................VDPVVREK..QLQQELLLIQQQQHIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.GERHRREQQL...........................................
HDAC5_HUMAN/67-164                   ................VDPTLREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLAakqq.qemlaAKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
A0A091J4F9_9AVES/34-124              ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
A0A091SXW2_9AVES/32-121              ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.-EMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
H2TZG2_TAKRU/20-108                  ................VDTAMREQ..QLQQELVLLKQQQELQKQMLFAEFQKKHEVLTRQHEVQLQEHL.KQ............Q.QELLA..........AKRQQE-LE..QKR.KLEQQ...........RHE-E.QEKHRLEQQL...........................................
H0X2U2_OTOGA/67-164                  ................VDPVLREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KCpphp...sppqqQ.QEMLA..........AKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
S9X6B2_CAMFR/267-359                 ...............a-EPALREQ..QLQQELLALKQKQQLQRQILIAEFQRQHEQLSRQHEAQLHEHI.KP............-.-----..........---------..---.-----...........-----.----------ladsilrsppgppappedtclghnavlieqlekrrggrer...
H2LSQ0_ORYLA/37-120                  ...............s-DHGLWER..QLQQELLLIQKQQQIQKQLLISEFQKQHEKLTRQHQAQLQEHL.KV............S.FSLNS..........---------..---.-----...........-----.----------ntagekcqndplkqskvicrtyqkl..................
M4A0P4_XIPMA/35-125                  ..............qa--ASVREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLQEHI.KQ............Q.QELLA..........LKHQQELLE..HQR.KMENH...........RLEQE.LEKQQREQKL...........................................
H2UG30_TAKRU/62-152                  ...............s-QPSVCDQ..QLQQELLTLKQKQQIQRQILIAEFQRQHEQLSRQHEAQLQEHI.KQ............Q.QELLA..........LKHQQELLE..HQR.KMENH...........RMEQE.LEKQQREQKL...........................................
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A2AWS5_MOUSE/68-156                  ................MDPALREQ..QLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
F7GZL0_MACMU/67-164                  ................VDPTLREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLAakqq.qemlaAKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
H2QD61_PANTR/68-165                  ................VDPTLREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLAakqq.qemlaAKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
A0A091CZ58_FUKDA/72-162              ................VDPVIREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
L5KSG9_PTEAL/77-167                  ...............s-EPALREQ..QLQQELLALKQKQQLQRQILIAEFQRQHEQLSRQHEAQLHEHV.KQ............Q.QELLA..........MKHQQELLE..HQR.KLERH...........RQEQE.LEKQHREQKL...........................................
A0A087VDU3_BALRE/30-120              ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
H2SKG6_TAKRU/40-131                  ..........qptfdh-----QEQ..QLQQELVALKHKQQLQRQLLIAEFQRQHEQLSRQHEIQLQEHI.KH............Q.QDLLA..........LKHQQELLE..HQR.KIEQQ...........RHEQE.LEKQQREYKL...........................................
A0A0D9R125_CHLSB/62-152              ...............a-EPALREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........MKHQQELLE..HQR.KLERH...........RQEQE.LEKQHREQKL...........................................
A0A087XQ10_POEFO/66-167              ................SDPGLWER..QLQQELLLIQKQQQIQKQLLISEFQKQHEKLTRQHQAQLQEHL.KL............Q.QELQA..........MKQQQELAE..KER.RLEQQqqqqqqqqqqnQQEKE.LERHRREQHV...........................................
F6TPS9_XENTR/62-152                  ...............q-EPGGREQ..QLQQELLALKQKQQIQRQLLIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QELLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.MEKQQREQKL...........................................
H3DQM5_TETNG/64-154                  ..............qq--PNHQEQ..QLQQELVALKHKQQLQRQLLIAEFQRQHEQLSRQHEIQLQEHI.KH............Q.QDLLA..........LKHQQELLE..HQR.KIEQQ...........RHEQE.LEKQQREYKL...........................................
A0A1B0GRH0_MOUSE/37-124              ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.K-............-.-ELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
W5PIS5_SHEEP/37-124                  ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.K-............-.-ELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
A0A094LGU5_ANTCR/31-121              ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELIE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
G1KJ78_ANOCA/62-152                  ...............a-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEILA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
A0A1B0GT67_MOUSE/58-148              ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
G1LY09_AILME/62-152                  ...............a-EPTLREQ..QLQQELLALKQKQQLQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QELLA..........MKHQQELLE..HQR.KLERH...........RQEQE.LEKQHREQKL...........................................
G3R4Y7_GORGO/68-165                  ................VDPTLREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLAxxxx.qemlaAKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
H2P937_PONAB/62-152                  ...............a-EPALREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........MKHQQELLE..HQR.KLERH...........RQEQE.LEKQHREQKL...........................................
F6VAF2_MACMU/37-124                  ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.K-............-.-ELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
G1LY17_AILME/62-152                  ...............a-EPTLREQ..QLQQELLALKQKQQLQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QELLA..........MKHQQELLE..HQR.KLERH...........RQEQE.LEKQHREQKL...........................................
A0A0Q3PA29_AMAAE/103-193             ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELIE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
A0A151PC11_ALLMI/66-146              ................VDPTVREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHEHLTRQHEVQLQKHL.KE............K.SKESA..........IASTEVKLK..LQE.-----...........-----.----------fllskskepi.................................
L5M2P1_MYODS/110-200                 ...............a-EPALREQ..QLQQELLALKQKQQLQRQILIAEFQRQHEQLSRQHEAQLHEHI.KH............Q.QELLA..........LKHQQELLE..HQR.KLERH...........RQEQA.LEKQHREQKL...........................................
F6X9B0_HORSE/61-149                  ................VDPALREQ..QLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
H3CU09_TETNG/64-154                  ..............qq--PNHQEQ..QLQQELVALKHKQQLQRQLLIAEFQRQHEQLSRQHEIQLQEHI.KH............Q.QDLLA..........LKHQQELLE..HQR.KIEQQ...........RHEQE.LEKQQREYKL...........................................
G1SVG4_RABIT/69-157                  ................VDPALREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
G1RSV2_NOMLE/62-152                  ...............a-EPALREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........MKHQQELLE..HQR.KLERH...........RQEQE.LEKQHREQKL...........................................
C9JD56_HUMAN/6-93                    ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.K-............-.-ELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
A0A1B0GSE4_MOUSE/37-124              ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.K-............-.-ELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
HDAC4_CHICK/62-151                   ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.-EMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
E5RQ38_RAT/37-127                    ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
A0A0R4J1F3_MOUSE/37-124              ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.K-............-.-ELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
S7P7V4_MYOBR/86-164                  ................VDPALREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KV............S.EEGAI..........ASTE-----..---.-----...........-----.----------vklrlqefllskskep...........................
H3B8Y5_LATCH/49-150                  ................VDPLFREQ..QLQHELLILKQQQQMQKQLLFAEFQKQHEHLTRQHEVQLQEHI.KQia........spH.QIFHVvymc.plssfMKRQQE-LE..QQQ.KLEQQ...........RQE-E.LEKQRLEQQL...........................................
F6XQL9_CALJA/51-141                  ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
W5N050_LEPOC/34-124                  ................ADPTVWER..QLHQELLLIQKQQQIQKQLLISEFQKQHESLTRQHQAQLQEHL.KL............Q.QELLA..........IKQQQELLE..KER.KAEQQ...........SQEQE.MERHRREQQ-f..........................................
M4AHC6_XIPMA/66-164                  ................SDPGLWER..QLQQELLLIQKQQQIQKQLLISEFQKQHEKLTRQHQAQLQEHL.KL............Q.QELQA..........MKQQQELAE..KER.RLEQQqqqq...qqqnQQEKE.LEWHRREQHV...........................................
H2UG32_TAKRU/19-109                  ..............gg--PSVCDQ..QLQQELLTLKQKQQIQRQILIAEFQRQHEQLSRQHEAQLQEHI.KQ............Q.QELLA..........LKHQQELLE..HQR.KMENH...........RMEQE.LEKQQREQKL...........................................
A0A0F8B282_LARCR/60-148              .............inh-----QEQ..QLQQELVALKHKQQLQRQLLIAEFQRQHEQLSRQHEVQLQEHI.KH............Q.QDLLA..........LKHQQELLE..HQR.KMEQQ...........RHEQE.LEKQQREYKL...........................................
HDAC4_MOUSE/61-151                   ...............l-EPALREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........MKHQQELLE..HQR.KLERH...........RQEQE.LEKQHREQKL...........................................
H0WX84_OTOGA/34-124                  ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
A0A131ZVL3_SARSC/173-267             ..........tsplal-------N..QFKQQLLELKQQQQLQQQLLLRHFQQQQQQLSEHHEKQVQEHI.REy.........ieK.QKLER..........EKIEQQ--A..AQI.AAAQA...........RTE-A.LERERSEKK-rlekdt.....................................
G3UN27_LOXAF/37-123                  ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.K-............-.-ELLA..........IKHQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQ--l..........................................
F6VAD3_MACMU/37-127                  ................VDPVVREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.VERHRREQQL...........................................
H2UG31_TAKRU/19-109                  ..............gg--PSVCDQ..QLQQELLTLKQKQQIQRQILIAEFQRQHEQLSRQHEAQLQEHI.KQ............Q.QELLA..........LKHQQELLE..HQR.KMENH...........RMEQE.LEKQQREQKL...........................................
H2UTM9_TAKRU/37-136                  ................SDPGMWER..QLQQELLLIQKQQQIQKQLLISEFQKQHEKLTRQHQAQLQEHL.KL............Q.QELQA..........MKKQQELAE..KER.RLEQQqqqq..qqqqnQQEKE.QERHRREQHV...........................................
F1QUC6_DANRE/37-127                  ...............s-EVTVWER..QLQQELLLIQKQQQIQKQLLITEFQKQHENLVRQHQAQIQEHL.KL............Q.QELHV..........MKQQQEQLE..KER.KLELQ...........SQERE.LERHRREQQV...........................................
K7FZ10_PELSI/34-124                  ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
A0A091M0E7_CARIC/56-145              ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.-EMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
B7ZDF7_MOUSE/67-155                  ................MDPALREQ..QLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
F7G734_MONDO/68-156                  ...............i-DPVLREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQR.KREQQ...........RQE-E.LEKQRLEQQL...........................................
A0A151PCC1_ALLMI/65-145              ................VDPTVREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHEHLTRQHEVQLQKHL.KE............K.SKESA..........IASTEVKLK..LQE.-----...........-----.----------fllskskepi.................................
HDAC4_RAT/61-151                     ...............l-EPALREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........MKHQQELLE..HQR.KLERH...........RQEQE.LEKQHREQKL...........................................
HDAC9_CHICK/37-127                   ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
A0A091FKU3_9AVES/19-102              .........dlrtdlr--------..------MMVPMQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
A0A091KJU0_COLST/31-120              ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.-EMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
W5L1S7_ASTMX/67-157                  ................VDSSLQDQ..QLQQELLSLKHKQQVQRQLLIAEFQRQHEQLSRQHEAQLQEHI.KH............Q.QDLLA..........LQHQQELLE..HHR.KMEKH...........RVEQE.LEKQQREQKL...........................................
U3JMK1_FICAL/27-72                   ...........slfls--------..------------------------------------------L.QQ............Q.QEMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
A0A093F5Y5_GAVST/34-124              ................VDPIMREK..QLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQ.KLEQQ...........RQEQE.LERHRREQQL...........................................
K7GJR1_PELSI/62-152                  ...............t-EPTLREQ..QLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........MKHQQELLE..HQR.KLEQH...........RQEQE.LEKQHREQKL...........................................
F6XF13_HORSE/62-150                  ................VDPALREQ..QLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
A0A0F8C7W6_LARCR/104-194             ..............vg--ASVREQ..QLQQELLTLKQKQQIQRQILIAEFQRQHEQLSRQHEAQLQEHI.KQ............Q.QELLA..........LKHQQELLE..HQR.KMENH...........RLEQE.LEKQQREQKL...........................................
G1P6Y3_MYOLU/68-156                  ................VDPALREQ..QLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QQMLA..........AKRQQE-LE..QQR.QREQQ...........RQE-E.LEKQRLEQQL...........................................
I3J443_ORENI/66-161                  ................SDPGLWER..QLQQELLLIQKQQQIQKQLLISEFQKQHEKLTRQHQAQLQEHL.KL............Q.QELQA..........MKQQQELAE..KER.RLEQQqq......qqsQQEKE.QEKHRREHHI...........................................
#=GC SS_cons                         ...............---HHHHHH..HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HH............H.HHHHH..........HHHCTGGG-..XXX.XXXXX...........XXXXX.XXXXXXXXXX...........................................
#=GC seq_cons                        .................DPslREp..QLQQELLhlpQQQQIQKQLLIAEFQKQHEpLTRQHpAQLQEHI.K.............Q.QElLA..........hKpQQELLE..+pp.KLEQp...........RQEQE.LE+p+REQpL...........................................
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