#=GF ID HDAC4_Gln
#=GF AC PF12203.6
#=GF DE Glutamine rich N terminal domain of histone deacetylase 4
#=GF AU Mistry J, Gavin OL
#=GF SE pdb_2o94
#=GF GA 25.00 25.00;
#=GF TC 25.70 25.70;
#=GF NC 24.40 24.60;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF RN [1]
#=GF RM 17360518
#=GF RT Crystal structure of a conserved N-terminal domain of histone
#=GF RT deacetylase 4 reveals functional insights into glutamine-rich
#=GF RT domains.
#=GF RA Guo L, Han A, Bates DL, Cao J, Chen L;
#=GF RL Proc Natl Acad Sci U S A. 2007;104:4297-4302.
#=GF DR INTERPRO; IPR024643;
#=GF CC This domain is found in eukaryotes, and is approximately 90
#=GF CC amino acids in length. The family is found in association with
#=GF CC Pfam:PF00850. The domain forms an alpha helix which complexes to
#=GF CC form a tetramer. The glutamine rich domains have many intra- and
#=GF CC inter-helical interactions which are thought to be involved in
#=GF CC reversible assembly and disassembly of proteins. The domain is
#=GF CC part of histone deacetylase 4 (HDAC4) which removes acetyl
#=GF CC groups from histones. This restores their positive charge to
#=GF CC allow stronger DNA binding thus restricting transcriptional
#=GF CC activity.
#=GF SQ 232
#=GS W5LGA0_ASTMX/1-39 AC W5LGA0.1
#=GS A0A0G2K082_RAT/37-127 AC A0A0G2K082.1
#=GS B7ZDF6_MOUSE/58-146 AC B7ZDF6.1
#=GS F6XPY2_CALJA/34-124 AC F6XPY2.1
#=GS HDAC9_HUMAN/37-124 AC Q9UKV0.2
#=GS W5MRU6_LEPOC/34-124 AC W5MRU6.1
#=GS H2TZF9_TAKRU/28-125 AC H2TZF9.1
#=GS H2UTN0_TAKRU/33-132 AC H2UTN0.1
#=GS H0V5J1_CAVPO/37-127 AC H0V5J1.1
#=GS V8P9U6_OPHHA/6-95 AC V8P9U6.1
#=GS F6SZ92_HORSE/38-128 AC F6SZ92.1
#=GS H0WQY7_OTOGA/1-90 AC H0WQY7.1
#=GS F1NP26_CHICK/35-125 AC F1NP26.2
#=GS G3U3T8_LOXAF/62-159 AC G3U3T8.1
#=GS F6XSP9_CALJA/62-152 AC F6XSP9.1
#=GS A0A0D9S118_CHLSB/68-125 AC A0A0D9S118.1
#=GS F1QRR4_DANRE/32-122 AC F1QRR4.1
#=GS F1MYR0_BOVIN/62-152 AC F1MYR0.2
#=GS H3D919_TETNG/28-116 AC H3D919.1
#=GS G3PNP4_GASAC/48-127 AC G3PNP4.1
#=GS H0VMW7_CAVPO/62-152 AC H0VMW7.1
#=GS F1P6I3_CANLF/68-156 AC F1P6I3.2
#=GS A0A096MQP8_PAPAN/37-124 AC A0A096MQP8.1
#=GS G1R0J0_NOMLE/68-165 AC G1R0J0.1
#=GS HDAC5_MOUSE/67-155 AC Q9Z2V6.2
#=GS G1KCW7_ANOCA/69-157 AC G1KCW7.2
#=GS G3REJ7_GORGO/35-125 AC G3REJ7.1
#=GS G3NZC1_GASAC/33-121 AC G3NZC1.1
#=GS G3NC45_GASAC/41-128 AC G3NC45.1
#=GS E0VLQ7_PEDHC/24-120 AC E0VLQ7.1
#=GS H0YWN9_TAEGU/2-92 AC H0YWN9.1
#=GS G3TEN3_LOXAF/37-126 AC G3TEN3.1
#=GS H2MV37_ORYLA/48-137 AC H2MV37.1
#=GS E1C7C0_CHICK/116-206 AC E1C7C0.2
#=GS H2NTV4_PONAB/68-153 AC H2NTV4.1
#=GS M4ASQ7_XIPMA/33-121 AC M4ASQ7.1
#=GS A0A087YGA8_POEFO/113-201 AC A0A087YGA8.2
#=GS G5BHI3_HETGA/56-146 AC G5BHI3.1
#=GS G1T7F7_RABIT/37-127 AC G1T7F7.2
#=GS H2TZG1_TAKRU/20-108 AC H2TZG1.1
#=GS S9YY75_9CETA/86-174 AC S9YY75.1
#=GS H3BVX6_TETNG/65-154 AC H3BVX6.1
#=GS W5PAD5_SHEEP/112-201 AC W5PAD5.1
#=GS G7P0S6_MACFA/37-127 AC G7P0S6.1
#=GS E7FH14_DANRE/50-138 AC E7FH14.1
#=GS G1LPL4_AILME/37-127 AC G1LPL4.1
#=GS F7IJK3_CALJA/35-137 AC F7IJK3.1
#=GS G1P7E4_MYOLU/32-122 AC G1P7E4.1
#=GS G3S8P2_GORGO/37-127 AC G3S8P2.1
#=GS M3WPZ1_FELCA/6-96 AC M3WPZ1.1
#=GS I3JGK7_ORENI/71-159 AC I3JGK7.1
#=GS U3IQJ6_ANAPL/31-121 AC U3IQJ6.1
#=GS F7ACM8_ORNAN/35-91 AC F7ACM8.1
#=GS H0YYG0_TAEGU/61-151 AC H0YYG0.1
#=GS HDAC4_HUMAN/62-152 AC P56524.3
#=GS HDAC4_HUMAN/62-152 DR PDB; 2O94 B; 62-129;
#=GS HDAC4_HUMAN/62-152 DR PDB; 2H8N A; 62-129;
#=GS HDAC4_HUMAN/62-152 DR PDB; 2O94 A; 62-129;
#=GS HDAC4_HUMAN/62-152 DR PDB; 2H8N B; 62-129;
#=GS HDAC4_HUMAN/62-152 DR PDB; 2O94 D; 62-129;
#=GS HDAC4_HUMAN/62-152 DR PDB; 2H8N C; 62-129;
#=GS HDAC4_HUMAN/62-152 DR PDB; 2O94 C; 62-129;
#=GS HDAC4_HUMAN/62-152 DR PDB; 2H8N D; 62-129;
#=GS G3SFB9_GORGO/62-152 AC G3SFB9.1
#=GS HDAC5_PONAB/67-164 AC Q5R902.1
#=GS F7GZK7_MACMU/67-164 AC F7GZK7.1
#=GS U3I9T4_ANAPL/30-121 AC U3I9T4.1
#=GS C3Z354_BRAFL/13-98 AC C3Z354.1
#=GS A0A096LZC9_POEFO/51-139 AC A0A096LZC9.1
#=GS W5JYJ6_ASTMX/53-141 AC W5JYJ6.1
#=GS I3IX83_ORENI/31-121 AC I3IX83.1
#=GS F6SA28_CALJA/37-124 AC F6SA28.1
#=GS I3JGK8_ORENI/33-121 AC I3JGK8.1
#=GS H2TZG3_TAKRU/20-108 AC H2TZG3.1
#=GS G1KLX7_ANOCA/37-126 AC G1KLX7.1
#=GS F1MNA5_BOVIN/67-164 AC F1MNA5.2
#=GS H2TZF8_TAKRU/35-123 AC H2TZF8.1
#=GS H3CSB1_TETNG/36-125 AC H3CSB1.1
#=GS F1SEI3_PIG/37-127 AC F1SEI3.2
#=GS HDA9B_DANRE/37-127 AC Q6PBI4.1
#=GS A0A093BLR2_CHAPE/56-145 AC A0A093BLR2.1
#=GS H3B734_LATCH/35-125 AC H3B734.1
#=GS G3T6K8_LOXAF/34-120 AC G3T6K8.1
#=GS G3PNP0_GASAC/71-148 AC G3PNP0.1
#=GS I3LM52_PIG/32-122 AC I3LM52.1
#=GS S9WMZ0_9CETA/6-83 AC S9WMZ0.1
#=GS H2MR85_ORYLA/19-107 AC H2MR85.1
#=GS B7ZDF5_MOUSE/86-174 AC B7ZDF5.1
#=GS F6ZVK4_ORNAN/37-127 AC F6ZVK4.2
#=GS I3IX82_ORENI/84-174 AC I3IX82.1
#=GS A0A0R4IAH0_DANRE/61-151 AC A0A0R4IAH0.1
#=GS J9P9N5_CANLF/41-129 AC J9P9N5.1
#=GS F6PUT1_CALJA/68-165 AC F6PUT1.1
#=GS M3VY28_FELCA/67-155 AC M3VY28.1
#=GS C9J1W4_HUMAN/37-127 AC C9J1W4.1
#=GS HDAC9_MOUSE/37-124 AC Q99N13.2
#=GS A0A087XDC8_POEFO/45-135 AC A0A087XDC8.2
#=GS H2QD60_PANTR/67-164 AC H2QD60.1
#=GS A0A091D6P9_FUKDA/114-204 AC A0A091D6P9.1
#=GS H3AFL1_LATCH/62-152 AC H3AFL1.1
#=GS H2QU82_PANTR/37-127 AC H2QU82.1
#=GS S9WA61_9CETA/267-362 AC S9WA61.1
#=GS G3UV76_MELGA/37-124 AC G3UV76.1
#=GS C9IZS0_HUMAN/37-127 AC C9IZS0.2
#=GS M7BEH0_CHEMY/16-103 AC M7BEH0.1
#=GS H3B8Y6_LATCH/41-129 AC H3B8Y6.1
#=GS A0A087X875_POEFO/74-162 AC A0A087X875.1
#=GS F7BD61_XENTR/37-129 AC F7BD61.1
#=GS G3HD66_CRIGR/22-112 AC G3HD66.1
#=GS F6QMU7_BOVIN/67-155 AC F6QMU7.1
#=GS G1S3X8_NOMLE/37-127 AC G1S3X8.1
#=GS H3DM61_TETNG/37-122 AC H3DM61.1
#=GS HDAC5_HUMAN/67-164 AC Q9UQL6.2
#=GS U3K5G0_FICAL/37-127 AC U3K5G0.1
#=GS H2UG33_TAKRU/3-104 AC H2UG33.1
#=GS A0A0P7VKZ6_9TELE/46-134 AC A0A0P7VKZ6.1
#=GS H2TZG2_TAKRU/20-108 AC H2TZG2.1
#=GS H0X2U2_OTOGA/67-164 AC H0X2U2.1
#=GS S9X6B2_9CETA/267-359 AC S9X6B2.1
#=GS H2LSQ0_ORYLA/37-120 AC H2LSQ0.1
#=GS E9QIJ9_DANRE/67-157 AC E9QIJ9.5
#=GS H2UG30_TAKRU/62-152 AC H2UG30.1
#=GS M4A0P4_XIPMA/35-125 AC M4A0P4.1
#=GS G3WQM8_SARHA/68-156 AC G3WQM8.1
#=GS C9J835_HUMAN/6-71 AC C9J835.7
#=GS F6ZBF4_ORNAN/62-152 AC F6ZBF4.1
#=GS F6X8E7_CANLF/37-127 AC F6X8E7.1
#=GS G5BZI9_HETGA/31-121 AC G5BZI9.1
#=GS H2UG34_TAKRU/15-63 AC H2UG34.1
#=GS G3NNN9_GASAC/68-139 AC G3NNN9.1
#=GS I3J9U5_ORENI/86-175 AC I3J9U5.1
#=GS H2PMR0_PONAB/37-124 AC H2PMR0.1
#=GS G3UF87_LOXAF/71-104 AC G3UF87.1
#=GS M3YR88_MUSPF/37-127 AC M3YR88.1
#=GS K7GKY8_PIG/30-117 AC K7GKY8.1
#=GS G7PKF6_MACFA/62-152 AC G7PKF6.1
#=GS L5KMM5_PTEAL/64-154 AC L5KMM5.1
#=GS G3HLJ3_CRIGR/68-156 AC G3HLJ3.1
#=GS G3U951_LOXAF/86-174 AC G3U951.1
#=GS F7HLM2_CALJA/57-147 AC F7HLM2.1
#=GS L5KRT3_PTEAL/86-143 AC L5KRT3.1
#=GS F7H3I3_CALJA/37-127 AC F7H3I3.1
#=GS M3ZIQ0_XIPMA/37-127 AC M3ZIQ0.1
#=GS Q3UJF1_MOUSE/68-156 AC Q3UJF1.1
#=GS F6VW34_MACMU/61-151 AC F6VW34.1
#=GS I3MGR1_ICTTR/35-125 AC I3MGR1.1
#=GS T1JB29_STRMM/58-149 AC T1JB29.1
#=GS B7ZDF4_MOUSE/26-114 AC B7ZDF4.1
#=GS L9KKK2_TUPCH/35-125 AC L9KKK2.1
#=GS A2AWS5_MOUSE/68-156 AC A2AWS5.1
#=GS F7GZL0_MACMU/67-164 AC F7GZL0.1
#=GS H2QD61_PANTR/68-165 AC H2QD61.1
#=GS F6Z8Z9_HORSE/37-127 AC F6Z8Z9.1
#=GS M7C334_CHEMY/54-122 AC M7C334.1
#=GS F1PRU6_CANLF/62-152 AC F1PRU6.2
#=GS A0A091CZ58_FUKDA/72-162 AC A0A091CZ58.1
#=GS L5KSG9_PTEAL/77-167 AC L5KSG9.1
#=GS F6X4A5_XENTR/70-158 AC F6X4A5.1
#=GS H2SKG6_TAKRU/40-131 AC H2SKG6.1
#=GS X1WED5_DANRE/43-129 AC X1WED5.1
#=GS A0A0D9R125_CHLSB/62-152 AC A0A0D9R125.1
#=GS H2UTM8_TAKRU/66-165 AC H2UTM8.1
#=GS A0A087XQ10_POEFO/66-167 AC A0A087XQ10.2
#=GS F6TPS9_XENTR/62-152 AC F6TPS9.1
#=GS H3DQM5_TETNG/64-154 AC H3DQM5.1
#=GS G3HYN8_CRIGR/1-35 AC G3HYN8.1
#=GS C9J0X4_HUMAN/35-123 AC C9J0X4.1
#=GS W5PIS5_SHEEP/37-124 AC W5PIS5.1
#=GS G1KJ78_ANOCA/62-152 AC G1KJ78.2
#=GS H2SKG7_TAKRU/36-126 AC H2SKG7.1
#=GS G1LY09_AILME/62-152 AC G1LY09.1
#=GS F6ZE39_HORSE/37-124 AC F6ZE39.1
#=GS V8PHC6_OPHHA/86-174 AC V8PHC6.1
#=GS G3R4Y7_GORGO/68-165 AC G3R4Y7.1
#=GS H2P937_PONAB/62-152 AC H2P937.1
#=GS F6VAF2_MACMU/37-124 AC F6VAF2.1
#=GS G1LY17_AILME/62-152 AC G1LY17.1
#=GS G3RTK4_GORGO/65-145 AC G3RTK4.1
#=GS M3WKB8_FELCA/1-68 AC M3WKB8.1
#=GS I3LYS2_ICTTR/37-124 AC I3LYS2.1
#=GS A0A087WSF0_MOUSE/61-112 AC A0A087WSF0.1
#=GS F7BC62_MONDO/91-181 AC F7BC62.2
#=GS L5M2P1_MYODS/110-200 AC L5M2P1.1
#=GS F6X9B0_HORSE/61-149 AC F6X9B0.1
#=GS A0A096NFQ1_PAPAN/37-127 AC A0A096NFQ1.1
#=GS H3CU09_TETNG/64-154 AC H3CU09.1
#=GS A0A0P7UZA5_9TELE/354-456 AC A0A0P7UZA5.1
#=GS G1SVG4_RABIT/69-157 AC G1SVG4.2
#=GS G1RSV2_NOMLE/62-152 AC G1RSV2.2
#=GS C9JD56_HUMAN/6-93 AC C9JD56.1
#=GS HDAC4_CHICK/62-151 AC P83038.1
#=GS E5RQ38_RAT/37-127 AC E5RQ38.1
#=GS A0A0P7XBI1_9TELE/62-152 AC A0A0P7XBI1.1
#=GS A0A0R4J1F3_MOUSE/37-124 AC A0A0R4J1F3.1
#=GS M3XM23_MUSPF/62-152 AC M3XM23.1
#=GS F1QUC5_DANRE/67-157 AC F1QUC5.1
#=GS H2TZG5_TAKRU/1-89 AC H2TZG5.1
#=GS W5LGJ9_ASTMX/41-131 AC W5LGJ9.1
#=GS F6U8V5_CALJA/6-96 AC F6U8V5.1
#=GS H3B8Y5_LATCH/49-150 AC H3B8Y5.1
#=GS F6XQL9_CALJA/51-141 AC F6XQL9.1
#=GS W5N050_LEPOC/34-124 AC W5N050.1
#=GS M4AHC6_XIPMA/66-164 AC M4AHC6.1
#=GS H2UG32_TAKRU/19-109 AC H2UG32.1
#=GS G5BN73_HETGA/419-507 AC G5BN73.1
#=GS HDAC4_MOUSE/61-151 AC Q6NZM9.1
#=GS H0WX84_OTOGA/34-124 AC H0WX84.1
#=GS H2TZG0_TAKRU/20-105 AC H2TZG0.1
#=GS F6VAD3_MACMU/37-127 AC F6VAD3.1
#=GS G3UN27_LOXAF/37-123 AC G3UN27.1
#=GS H2UG31_TAKRU/19-109 AC H2UG31.1
#=GS H2UTM9_TAKRU/37-136 AC H2UTM9.1
#=GS F1QUC6_DANRE/37-127 AC F1QUC6.2
#=GS B7ZDF7_MOUSE/67-155 AC B7ZDF7.1
#=GS A0A0D9RM59_CHLSB/37-127 AC A0A0D9RM59.1
#=GS F7G734_MONDO/68-156 AC F7G734.2
#=GS F1MWS5_BOVIN/37-124 AC F1MWS5.2
#=GS HDAC4_RAT/61-151 AC Q99P99.2
#=GS G1PQF2_MYOLU/33-123 AC G1PQF2.1
#=GS G1MJ38_AILME/68-152 AC G1MJ38.1
#=GS HDAC9_CHICK/37-127 AC Q5ZKH6.1
#=GS I3MXF0_ICTTR/68-159 AC I3MXF0.1
#=GS C9J481_HUMAN/31-121 AC C9J481.1
#=GS M3YDP5_MUSPF/40-128 AC M3YDP5.1
#=GS H2SKG8_TAKRU/2-43 AC H2SKG8.1
#=GS L9KKS0_TUPCH/314-404 AC L9KKS0.1
#=GS B7Z3P7_HUMAN/37-127 AC B7Z3P7.1
#=GS H0VUA3_CAVPO/67-98 AC H0VUA3.1
#=GS W5L1S7_ASTMX/67-157 AC W5L1S7.1
#=GS F6VAE2_MACMU/32-119 AC F6VAE2.1
#=GS G1NCZ1_MELGA/34-124 AC G1NCZ1.1
#=GS U3JMK1_FICAL/27-72 AC U3JMK1.1
#=GS L8Y465_TUPCH/86-150 AC L8Y465.1
#=GS H2QJQ3_PANTR/62-152 AC H2QJQ3.1
#=GS G3RCU7_GORGO/37-124 AC G3RCU7.1
#=GS B5MCF1_HUMAN/65-155 AC B5MCF1.2
#=GS F6XF13_HORSE/62-150 AC F6XF13.1
#=GS G1P6Y3_MYOLU/68-156 AC G1P6Y3.1
#=GS I3J443_ORENI/66-161 AC I3J443.1
#=GS F7GQ46_CALJA/66-136 AC F7GQ46.1
W5LGA0_ASTMX/1-39 ................---------------------------------------------------.-H............Q.QELLA..........LKHQQELLE..HQRKLERH...........RREQE.LEKQQREQKL...........................................
A0A0G2K082_RAT/37-127 ................VDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQKLEQQ...........RQEQE.VERHRREQQL...........................................
B7ZDF6_MOUSE/58-146 ................MDPALREQQLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQRQREQQ...........RQE-E.LEKQRLEQQL...........................................
F6XPY2_CALJA/34-124 ................VDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQKLEQQ...........RQEQE.VERHRREQQL...........................................
HDAC9_HUMAN/37-124 ................VDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.K-............-.-ELLA..........IKQQQELLE..KEQKLEQQ...........RQEQE.VERHRREQQL...........................................
W5MRU6_LEPOC/34-124 ................ADPSLREQQLQQELIALKQKQQIQRQLLIAEFQRQHEQLSRQHEAQLQEHV.KH............Q.QDMLA..........LKHQQELLE..HQRKMEKH...........RHEQE.MEKHQREQKL...........................................
H2TZF9_TAKRU/28-125 ................VDTAMREQQLQQELVLLKQQQELQKQMLFAEFQKKHEVLTRQHEVQLQEHL.KYcpcl...cvykqQ.QELLA..........AKRQQE-LE..QKRKLEQQ...........RHE-E.QEKHRLEQQL...........................................
H2UTN0_TAKRU/33-132 ................SDPGMWERQLQQELLLIQKQQQIQKQLLISEFQKQHEKLTRQHQAQLQEHL.KL............Q.QELQA..........MKKQQELAE..KERRLEQQqqqq..qqqqnQQEKE.QERHRREQHV...........................................
H0V5J1_CAVPO/37-127 ................VDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQKLEQQ...........RQEQE.VERHRREQQL...........................................
V8P9U6_OPHHA/6-95 ................MDPLMQEKQLQQELILIQHQQQIQKQLLIAEFQKQHENLTRQHQAQIQEHM.KL............Q.KELLA..........IKYQQELLE..KEQKLEQQ...........RQEQE.LERHRREQ--c..........................................
F6SZ92_HORSE/38-128 ...............t-EPTLREQQLQQELLALKQKQQLQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QELLA..........MKHQQELLE..HQRKLERH...........RQEQE.LEKQHREQKL...........................................
H0WQY7_OTOGA/1-90 ................-EPALREQQLQQELLALKQKQQIQRQLLIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........MKHQQELLE..HQRKLERH...........RQEQE.LEKQHREQKL...........................................
F1NP26_CHICK/35-125 ...............t-EPTLREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........MKHQQELLE..HQRKLEQH...........RQEQE.LEKQHREQKL...........................................
G3U3T8_LOXAF/62-159 ................VDPALREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KVtega...vplqqQ.QEMLA..........AQRQQE-LE..QQRQREQQ...........RQE-E.LEKQRLEQQL...........................................
F6XSP9_CALJA/62-152 ...............a-EPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........MKHQQELLE..HQRKLERH...........RQEQE.LEKQHREQKL...........................................
A0A0D9S118_CHLSB/68-125 ................VDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KV............S.E----..........---------..--------...........-----.----------rga........................................
F1QRR4_DANRE/32-122 ................TDPAQREHQLQQELLALKQKQQIQRQLLIEEFQRQHEQLSRQHEAQLQEHV.KH............Q.QDLLA..........LKHQQELLE..HQRKLERH...........RQEQE.MEKQQREQKL...........................................
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H2TZG0_TAKRU/20-105 ................VDTAMREQQLQQELVLLKQQQELQKQMLFAEFQKKHEVLTRQHEVQLQEHL.K-............-.-ELLA..........AKRQQE-LE..QKRKLEQQ...........RHE-E.QEKHRLEQQL...........................................
F6VAD3_MACMU/37-127 ................VDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQKLEQQ...........RQEQE.VERHRREQQL...........................................
G3UN27_LOXAF/37-123 ................VDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.K-............-.-ELLA..........IKHQQELLE..KEQKLEQQ...........RQEQE.VERHRREQ--l..........................................
H2UG31_TAKRU/19-109 ..............gg--PSVCDQQLQQELLTLKQKQQIQRQILIAEFQRQHEQLSRQHEAQLQEHI.KQ............Q.QELLA..........LKHQQELLE..HQRKMENH...........RMEQE.LEKQQREQKL...........................................
H2UTM9_TAKRU/37-136 ................SDPGMWERQLQQELLLIQKQQQIQKQLLISEFQKQHEKLTRQHQAQLQEHL.KL............Q.QELQA..........MKKQQELAE..KERRLEQQqqqq..qqqqnQQEKE.QERHRREQHV...........................................
F1QUC6_DANRE/37-127 ...............s-EVTVWERQLQQELLLIQKQQQIQKQLLITEFQKQHENLVRQHQAQIQEHL.KL............Q.QELHV..........MKQQQEQLE..KERKLELQ...........SQERE.LERHRREQQV...........................................
B7ZDF7_MOUSE/67-155 ................MDPALREQQLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQRQREQQ...........RQE-E.LEKQRLEQQL...........................................
A0A0D9RM59_CHLSB/37-127 ................VDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQKLEQQ...........RQEQE.VERHRREQQL...........................................
F7G734_MONDO/68-156 ...............i-DPVLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQRKREQQ...........RQE-E.LEKQRLEQQL...........................................
F1MWS5_BOVIN/37-124 ................VDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.K-............-.-ELLA..........IKQQQELLE..KEQKLEQQ...........RQEQE.VERHRREQQL...........................................
HDAC4_RAT/61-151 ...............l-EPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........MKHQQELLE..HQRKLERH...........RQEQE.LEKQHREQKL...........................................
G1PQF2_MYOLU/33-123 ...............a-EPALREQQLQQELLALKQKQQLQRQILIAEFQRQHEQLSRQHEAQLHEHI.KH............Q.QELLA..........LKHQQELLE..HQRKLERH...........RQEQA.LEKQHREQKL...........................................
G1MJ38_AILME/68-152 ................VDPALREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KV............S.EG---..........---------..--------...........-----.----------gaggpprpptpartwlkeelekqrleqql..............
HDAC9_CHICK/37-127 ................VDPIMREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQKLEQQ...........RQEQE.LERHRREQQL...........................................
I3MXF0_ICTTR/68-159 ................VDPALREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KVs.........kqQ.QEMLA..........AKRQQE-LE..QQRQREQQ...........RQE-E.LEKQRLEQQL...........................................
C9J481_HUMAN/31-121 ...............a-EPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........MKHQQELLE..HQRKLERH...........RQEQE.LEKQHREQKL...........................................
M3YDP5_MUSPF/40-128 ................VDPALREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQRQREQQ...........RQE-E.LEKQRLEQQL...........................................
H2SKG8_TAKRU/2-43 ..............lh---------------------------------------------------.QH............Q.QDLLA..........LKHQQELLE..HQRKIEQQ...........RHEQE.LEKQQREYKL...........................................
L9KKS0_TUPCH/314-404 ...............a-EPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........LKHQQELLE..HQRKLERH...........RQEQE.LEKQHREQKL...........................................
B7Z3P7_HUMAN/37-127 ................VDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQKLEQQ...........RQEQE.VERHRREQQL...........................................
H0VUA3_CAVPO/67-98 .............dpv--------------------------LLFAEFQKQHAHLTRQHEAQLQKHL.Q-............-.-----..........---------..--------...........-----.----------vgv........................................
W5L1S7_ASTMX/67-157 ................VDSSLQDQQLQQELLSLKHKQQVQRQLLIAEFQRQHEQLSRQHEAQLQEHI.KH............Q.QDLLA..........LQHQQELLE..HHRKMEKH...........RVEQE.LEKQQREQKL...........................................
F6VAE2_MACMU/32-119 ................VDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.K-............-.-ELLA..........IKQQQELLE..KEQKLEQQ...........RQEQE.VERHRREQQL...........................................
G1NCZ1_MELGA/34-124 ................VDPIMREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQKLEQQ...........RQEQE.LERHRREQQL...........................................
U3JMK1_FICAL/27-72 ...........slfls--------------------------------------------------L.QQ............Q.QEMLA..........MKHQQELLE..HQRKLEQH...........RQEQE.LEKQHREQKL...........................................
L8Y465_TUPCH/86-150 ................VDPALREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KV............S.E----..........---------..--------...........-----.----------qgvgglqtsd.................................
H2QJQ3_PANTR/62-152 ...............a-EPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHI.KQ............Q.QEMLA..........MKHQQELLE..HQRKLERH...........RQEQE.LEKQHREQKL...........................................
G3RCU7_GORGO/37-124 ................VDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.K-............-.-ELLA..........IKQQQELLE..KEQKLEQQ...........RQEQE.VERHRREQQL...........................................
B5MCF1_HUMAN/65-155 ................VDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHI.KL............Q.QELLA..........IKQQQELLE..KEQKLEQQ...........RQEQE.VERHRREQQL...........................................
F6XF13_HORSE/62-150 ................VDPALREQQLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKRQQE-LE..QQRQREQQ...........RQE-E.LEKQRLEQQL...........................................
G1P6Y3_MYOLU/68-156 ................VDPALREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QQMLA..........AKRQQE-LE..QQRQREQQ...........RQE-E.LEKQRLEQQL...........................................
I3J443_ORENI/66-161 ................SDPGLWERQLQQELLLIQKQQQIQKQLLISEFQKQHEKLTRQHQAQLQEHL.KL............Q.QELQA..........MKQQQELAE..KERRLEQQqq......qqsQQEKE.QEKHRREHHI...........................................
F7GQ46_CALJA/66-136 ............svdp-------------------------TLLFAEFQKQHDHLTRQHEVQLQKHL.KQ............Q.QEMLA..........AKQQQEMLA..-AEELEKQ...........RLEQQ.L---------lilrnkekske................................
#=GC SS_cons ...............---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH.HH............H.HHHHH..........HHHCTGGG-..XXXXXXXX...........XXXXX.XXXXXXXXXX...........................................
#=GC seq_cons .................DPslREpQLQQELLhlKQQQQlQKQLLIAEFQKQHEpLTRQHEAQLQEHl.K.............Q.QElLA..........hKcQQELLE..+pRKlEQQ...........RQEpE.lE+p+REQpL...........................................
//
