GenomeNet

Database: Pfam
Entry: HDAC4_Gln
LinkDB: HDAC4_Gln
Original site: HDAC4_Gln 
#=GF ID   HDAC4_Gln
#=GF AC   PF12203.4
#=GF DE   Glutamine rich N terminal domain of histone deacetylase 4
#=GF AU   Mistry J, Gavin OL
#=GF SE   pdb_2o94
#=GF GA   25.00 25.00;
#=GF TC   25.00 25.00;
#=GF NC   24.90 24.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF RN   [1]
#=GF RM   17360518
#=GF RT   Crystal structure of a conserved N-terminal domain of histone
#=GF RT   deacetylase 4 reveals functional insights into glutamine-rich
#=GF RT   domains.
#=GF RA   Guo L, Han A, Bates DL, Cao J, Chen L;
#=GF RL   Proc Natl Acad Sci U S A. 2007;104:4297-4302.
#=GF DR   INTERPRO; IPR024643;
#=GF CC   This domain is found in eukaryotes, and is approximately 90
#=GF CC   amino acids in length. The family is found in association with
#=GF CC   Pfam:PF00850. The domain forms an alpha helix which complexes to
#=GF CC   form a tetramer. The glutamine rich domains have many intra- and
#=GF CC   inter-helical interactions which are thought to be involved in
#=GF CC   reversible assembly and disassembly of proteins. The domain is
#=GF CC   part of histone deacetylase 4 (HDAC4) which removes acetyl
#=GF CC   groups from histones. This restores their positive charge to
#=GF CC   allow stronger DNA binding thus restricting transcriptional
#=GF CC   activity.
#=GF SQ   282
#=GS R7VQN6_COLLI/56-145   AC R7VQN6.1
#=GS E9QIJ9_DANRE/67-157   AC E9QIJ9.2
#=GS B7ZDF6_MOUSE/58-146   AC B7ZDF6.1
#=GS F6XPY2_CALJA/34-124   AC F6XPY2.1
#=GS W5MRU6_LEPOC/34-124   AC W5MRU6.1
#=GS H0V5J1_CAVPO/37-127   AC H0V5J1.1
#=GS V8P9U6_OPHHA/6-95     AC V8P9U6.1
#=GS H3DM61_TETNG/37-123   AC H3DM61.1
#=GS F6SZ92_HORSE/38-128   AC F6SZ92.1
#=GS F1NP26_CHICK/35-125   AC F1NP26.2
#=GS G3U3T8_LOXAF/62-159   AC G3U3T8.1
#=GS H3D919_TETNG/28-116   AC H3D919.1
#=GS H0VMW7_CAVPO/62-152   AC H0VMW7.1
#=GS F1P6I3_CANFA/68-156   AC F1P6I3.2
#=GS G1R0J0_NOMLE/68-165   AC G1R0J0.1
#=GS I3J9U5_ORENI/87-175   AC I3J9U5.1
#=GS E0VLQ7_PEDHC/24-120   AC E0VLQ7.1
#=GS E7FB70_DANRE/50-140   AC E7FB70.1
#=GS H2MV37_ORYLA/48-137   AC H2MV37.1
#=GS E1C7C0_CHICK/116-206  AC E1C7C0.2
#=GS H2TZG1_TAKRU/20-108   AC H2TZG1.1
#=GS S9YY75_9CETA/86-174   AC S9YY75.1
#=GS W5PAD5_SHEEP/112-201  AC W5PAD5.1
#=GS B7Z8G5_HUMAN/57-147   AC B7Z8G5.1
#=GS E7FH14_DANRE/50-138   AC E7FH14.1
#=GS M3WPZ1_FELCA/6-96     AC M3WPZ1.1
#=GS G1P7E4_MYOLU/32-122   AC G1P7E4.1
#=GS G3S8P2_GORGO/37-127   AC G3S8P2.1
#=GS I3JGK7_ORENI/71-159   AC I3JGK7.1
#=GS G3PNP0_GASAC/74-148   AC G3PNP0.1
#=GS U3IQJ6_ANAPL/31-121   AC U3IQJ6.1
#=GS Q3U2E0_MOUSE/68-156   AC Q3U2E0.1
#=GS F7ACM8_ORNAN/35-91    AC F7ACM8.1
#=GS U3BMX4_CALJA/37-124   AC U3BMX4.1
#=GS U6DRX6_NEOVI/77-128   AC U6DRX6.1
#=GS S9WA61_9CETA/267-361  AC S9WA61.1
#=GS HDAC5_PONAB/67-164    AC Q5R902.1
#=GS W5JYJ6_ASTMX/53-141   AC W5JYJ6.1
#=GS H2TZF8_TAKRU/35-123   AC H2TZF8.1
#=GS B7Z8L3_HUMAN/1-35     AC B7Z8L3.1
#=GS K9IVU4_DESRO/111-198  AC K9IVU4.1
#=GS A1YFS8_SAGLB/29-80    AC A1YFS8.1
#=GS S9WMZ0_9CETA/6-83     AC S9WMZ0.1
#=GS H2MR85_ORYLA/19-107   AC H2MR85.1
#=GS B7ZDF5_MOUSE/86-174   AC B7ZDF5.1
#=GS HDAC5_CRIGR/67-155    AC Q80ZH1.1
#=GS J9P9N5_CANFA/41-129   AC J9P9N5.1
#=GS F6PUT1_CALJA/68-165   AC F6PUT1.1
#=GS H3AFL1_LATCH/62-152   AC H3AFL1.1
#=GS H2QU82_PANTR/37-127   AC H2QU82.1
#=GS F7IJK3_CALJA/35-136   AC F7IJK3.1
#=GS H3B8Y6_LATCH/41-129   AC H3B8Y6.1
#=GS F7BD61_XENTR/37-129   AC F7BD61.1
#=GS F6QMU7_BOVIN/67-155   AC F6QMU7.1
#=GS G3HD66_CRIGR/22-112   AC G3HD66.1
#=GS HDAC5_HUMAN/67-164    AC Q9UQL6.2
#=GS H2UG34_TAKRU/16-63    AC H2UG34.1
#=GS H2TZG2_TAKRU/20-108   AC H2TZG2.1
#=GS H0X2U2_OTOGA/67-164   AC H0X2U2.1
#=GS H2LSQ0_ORYLA/37-120   AC H2LSQ0.1
#=GS M4A0P4_XIPMA/35-125   AC M4A0P4.1
#=GS H2UG30_TAKRU/62-152   AC H2UG30.1
#=GS H9ET66_MACMU/62-152   AC H9ET66.1
#=GS G3WQM8_SARHA/68-156   AC G3WQM8.1
#=GS Q4SMC8_TETNG/58-147   AC Q4SMC8.1
#=GS F6X8E7_CANFA/37-127   AC F6X8E7.1
#=GS G5BZI9_HETGA/31-121   AC G5BZI9.1
#=GS U3DLY4_CALJA/62-152   AC U3DLY4.1
#=GS G3NNN9_GASAC/68-139   AC G3NNN9.1
#=GS G3UF87_LOXAF/71-104   AC G3UF87.1
#=GS U3CUE3_CALJA/68-165   AC U3CUE3.1
#=GS M3YR88_MUSPF/37-127   AC M3YR88.1
#=GS G3HLJ3_CRIGR/68-156   AC G3HLJ3.1
#=GS G3U951_LOXAF/86-174   AC G3U951.1
#=GS L5KRT3_PTEAL/86-143   AC L5KRT3.1
#=GS A2T7X3_PONPY/1-39     AC A2T7X3.1
#=GS Q2T9N9_BOVIN/67-155   AC Q2T9N9.1
#=GS M3ZIQ0_XIPMA/37-127   AC M3ZIQ0.1
#=GS D2HCU8_AILME/111-200  AC D2HCU8.1
#=GS Q3UJF1_MOUSE/68-156   AC Q3UJF1.1
#=GS I3MGR1_SPETR/35-125   AC I3MGR1.1
#=GS B7ZDF4_MOUSE/26-114   AC B7ZDF4.1
#=GS L9KKK2_TUPCH/35-125   AC L9KKK2.1
#=GS F6Z8Z9_HORSE/37-127   AC F6Z8Z9.1
#=GS F1PRU6_CANFA/62-152   AC F1PRU6.2
#=GS M7C334_CHEMY/54-122   AC M7C334.1
#=GS F6X4A5_XENTR/70-158   AC F6X4A5.1
#=GS X1WED5_DANRE/43-129   AC X1WED5.1
#=GS H2UTM8_TAKRU/66-165   AC H2UTM8.1
#=GS L8HSP2_9CETA/34-124   AC L8HSP2.1
#=GS G3HYN8_CRIGR/1-35     AC G3HYN8.1
#=GS C9J0X4_HUMAN/35-123   AC C9J0X4.1
#=GS V9K8F9_CALMI/118-213  AC V9K8F9.1
#=GS H2SKG7_TAKRU/36-126   AC H2SKG7.1
#=GS V8PHC6_OPHHA/86-174   AC V8PHC6.1
#=GS H9FNB9_MACMU/68-161   AC H9FNB9.1
#=GS F6ZE39_HORSE/37-124   AC F6ZE39.1
#=GS U6DG38_NEOVI/1-86     AC U6DG38.1
#=GS G3RTK4_GORGO/65-145   AC G3RTK4.1
#=GS M3WKB8_FELCA/1-68     AC M3WKB8.1
#=GS I3LYS2_SPETR/37-124   AC I3LYS2.1
#=GS U3F7Q2_CALJA/37-127   AC U3F7Q2.1
#=GS F7BC62_MONDO/91-181   AC F7BC62.2
#=GS H9ZFU6_MACMU/62-152   AC H9ZFU6.1
#=GS Q86YH7_HUMAN/1-35     AC Q86YH7.1
#=GS Q8N879_HUMAN/56-146   AC Q8N879.1
#=GS F5H5W4_HUMAN/31-121   AC F5H5W4.1
#=GS F1QUC5_DANRE/67-157   AC F1QUC5.1
#=GS M3XM23_MUSPF/62-152   AC M3XM23.1
#=GS W5LGJ9_ASTMX/41-131   AC W5LGJ9.1
#=GS H2TZG5_TAKRU/1-89     AC H2TZG5.1
#=GS F6U8V5_CALJA/6-96     AC F6U8V5.1
#=GS B4DGT4_HUMAN/67-164   AC B4DGT4.1
#=GS Q2VC82_DANRE/32-122   AC Q2VC82.1
#=GS L8HWG2_9CETA/111-171  AC L8HWG2.1
#=GS K7CLL5_PANTR/37-127   AC K7CLL5.1
#=GS G5BN73_HETGA/419-507  AC G5BN73.1
#=GS S9X6B2_9CETA/267-355  AC S9X6B2.1
#=GS H2TZG0_TAKRU/20-105   AC H2TZG0.1
#=GS F1MWS5_BOVIN/37-124   AC F1MWS5.2
#=GS G1PQF2_MYOLU/33-123   AC G1PQF2.1
#=GS G1MJ38_AILME/68-152   AC G1MJ38.1
#=GS I3MXF0_SPETR/68-159   AC I3MXF0.1
#=GS C9J481_HUMAN/31-121   AC C9J481.1
#=GS H2UG33_TAKRU/4-104    AC H2UG33.1
#=GS M3YDP5_MUSPF/40-128   AC M3YDP5.1
#=GS B7Z3P7_HUMAN/37-127   AC B7Z3P7.1
#=GS L9KKS0_TUPCH/314-404  AC L9KKS0.1
#=GS H0VUA3_CAVPO/67-98    AC H0VUA3.1
#=GS F6VAE2_MACMU/32-119   AC F6VAE2.1
#=GS G1NCZ1_MELGA/34-124   AC G1NCZ1.1
#=GS L8Y465_TUPCH/86-150   AC L8Y465.1
#=GS Q5R6M0_PONAB/65-155   AC Q5R6M0.1
#=GS H2QJQ3_PANTR/62-152   AC H2QJQ3.1
#=GS B5MCF1_HUMAN/65-155   AC B5MCF1.2
#=GS G3RCU7_GORGO/37-124   AC G3RCU7.1
#=GS G3NC45_GASAC/40-128   AC G3NC45.1
#=GS HDAC9_HUMAN/37-124    AC Q9UKV0.2
#=GS H2TZF9_TAKRU/28-125   AC H2TZF9.1
#=GS M3TYB6_PIG/68-156     AC M3TYB6.1
#=GS H2UTN0_TAKRU/33-132   AC H2UTN0.1
#=GS H0WQY7_OTOGA/1-90     AC H0WQY7.1
#=GS F6XSP9_CALJA/62-152   AC F6XSP9.1
#=GS A1YGF8_PANPA/1-39     AC A1YGF8.1
#=GS F1QRR4_DANRE/32-122   AC F1QRR4.1
#=GS Q68D71_HUMAN/37-127   AC Q68D71.1
#=GS U3DP42_CALJA/68-165   AC U3DP42.1
#=GS F1MYR0_BOVIN/62-152   AC F1MYR0.2
#=GS G3PNP4_GASAC/48-127   AC G3PNP4.1
#=GS HDAC5_MOUSE/67-155    AC Q9Z2V6.2
#=GS G3REJ7_GORGO/35-125   AC G3REJ7.1
#=GS G1KCW7_ANOCA/69-157   AC G1KCW7.2
#=GS H0YWN9_TAEGU/2-92     AC H0YWN9.1
#=GS G3TEN3_LOXAF/37-126   AC G3TEN3.1
#=GS H2NTV4_PONAB/68-153   AC H2NTV4.1
#=GS M4ASQ7_XIPMA/33-121   AC M4ASQ7.1
#=GS G5BHI3_HETGA/56-146   AC G5BHI3.1
#=GS T1JB29_STRMM/58-150   AC T1JB29.1
#=GS G1T7F7_RABIT/37-127   AC G1T7F7.2
#=GS H3BVX6_TETNG/65-154   AC H3BVX6.1
#=GS G7P0S6_MACFA/37-127   AC G7P0S6.1
#=GS G1LPL4_AILME/37-127   AC G1LPL4.1
#=GS H2UG31_TAKRU/20-109   AC H2UG31.1
#=GS C3Z354_BRAFL/12-98    AC C3Z354.1
#=GS S7PSN1_MYOBR/82-172   AC S7PSN1.1
#=GS H0YYG0_TAEGU/61-151   AC H0YYG0.1
#=GS G3SFB9_GORGO/62-152   AC G3SFB9.1
#=GS HDAC4_HUMAN/62-152    AC P56524.3
#=GS HDAC4_HUMAN/62-152    DR PDB; 2H8N A; 62-129;
#=GS HDAC4_HUMAN/62-152    DR PDB; 2H8N B; 62-129;
#=GS HDAC4_HUMAN/62-152    DR PDB; 2H8N C; 62-129;
#=GS HDAC4_HUMAN/62-152    DR PDB; 2O94 C; 62-129;
#=GS HDAC4_HUMAN/62-152    DR PDB; 2O94 B; 62-129;
#=GS HDAC4_HUMAN/62-152    DR PDB; 2O94 A; 62-129;
#=GS HDAC4_HUMAN/62-152    DR PDB; 2O94 D; 62-129;
#=GS HDAC4_HUMAN/62-152    DR PDB; 2H8N D; 62-129;
#=GS F7GZK7_MACMU/67-164   AC F7GZK7.1
#=GS U3I9T4_ANAPL/30-121   AC U3I9T4.1
#=GS I3IX83_ORENI/31-121   AC I3IX83.1
#=GS F6SA28_CALJA/37-124   AC F6SA28.1
#=GS I3JGK8_ORENI/33-121   AC I3JGK8.1
#=GS H2TZG3_TAKRU/20-108   AC H2TZG3.1
#=GS F1MNA5_BOVIN/67-164   AC F1MNA5.2
#=GS G1KLX7_ANOCA/37-126   AC G1KLX7.1
#=GS F8SRE3_SHEEP/37-124   AC F8SRE3.1
#=GS F7GQ46_CALJA/66-137   AC F7GQ46.1
#=GS H3CSB1_TETNG/36-125   AC H3CSB1.1
#=GS F1SEI3_PIG/37-127     AC F1SEI3.2
#=GS HDA9B_DANRE/37-127    AC Q6PBI4.1
#=GS G3T6K8_LOXAF/34-120   AC G3T6K8.1
#=GS H3B734_LATCH/35-125   AC H3B734.1
#=GS H9ZFU5_MACMU/62-152   AC H9ZFU5.1
#=GS Q6P9T4_MOUSE/67-155   AC Q6P9T4.1
#=GS I3LM52_PIG/32-122     AC I3LM52.1
#=GS H9YUC4_MACMU/68-165   AC H9YUC4.1
#=GS A2D554_ATEGE/29-80    AC A2D554.1
#=GS F6ZVK4_ORNAN/37-127   AC F6ZVK4.2
#=GS I3IX82_ORENI/84-174   AC I3IX82.1
#=GS G7MLR0_MACMU/37-127   AC G7MLR0.1
#=GS HDAC9_XENLA/64-156    AC Q9YGY4.2
#=GS M3VY28_FELCA/67-155   AC M3VY28.1
#=GS C9J1W4_HUMAN/37-127   AC C9J1W4.1
#=GS HDAC9_MOUSE/37-124    AC Q99N13.2
#=GS H2QD60_PANTR/67-164   AC H2QD60.1
#=GS Q08BS8_DANRE/32-122   AC Q08BS8.1
#=GS U3ES97_CALJA/67-164   AC U3ES97.1
#=GS G3UV76_MELGA/37-124   AC G3UV76.1
#=GS M7BEH0_CHEMY/16-103   AC M7BEH0.1
#=GS C9IZS0_HUMAN/37-127   AC C9IZS0.2
#=GS G1S3X8_NOMLE/37-127   AC G1S3X8.1
#=GS S4RJL9_PETMA/5-103    AC S4RJL9.1
#=GS U3K5G0_FICAL/37-127   AC U3K5G0.1
#=GS B7Z8I2_HUMAN/31-121   AC B7Z8I2.1
#=GS F6ZBF4_ORNAN/62-152   AC F6ZBF4.1
#=GS G7NIW9_MACMU/68-157   AC G7NIW9.1
#=GS V9KH13_CALMI/62-150   AC V9KH13.1
#=GS H2PMR0_PONAB/37-124   AC H2PMR0.1
#=GS G3NZC1_GASAC/33-120   AC G3NZC1.1
#=GS V5H4B2_ANOGL/13-115   AC V5H4B2.1
#=GS G7PKF6_MACFA/62-152   AC G7PKF6.1
#=GS K7GKY8_PIG/30-117     AC K7GKY8.1
#=GS L5KMM5_PTEAL/64-154   AC L5KMM5.1
#=GS F7HLM2_CALJA/57-147   AC F7HLM2.1
#=GS F7H3I3_CALJA/37-127   AC F7H3I3.1
#=GS C9J835_HUMAN/6-70     AC C9J835.2
#=GS Q4SK37_TETNG/1-86     AC Q4SK37.1
#=GS S7P4E9_MYOBR/67-157   AC S7P4E9.1
#=GS F6VW34_MACMU/61-151   AC F6VW34.1
#=GS H2UG32_TAKRU/20-109   AC H2UG32.1
#=GS F7GZL0_MACMU/67-164   AC F7GZL0.1
#=GS H2QD61_PANTR/68-165   AC H2QD61.1
#=GS A2AWS5_MOUSE/68-156   AC A2AWS5.1
#=GS H2SKG6_TAKRU/41-131   AC H2SKG6.1
#=GS L5KSG9_PTEAL/77-167   AC L5KSG9.1
#=GS U3E2F1_CALJA/67-164   AC U3E2F1.1
#=GS X2JBC8_PAROL/43-131   AC X2JBC8.1
#=GS U3EF87_CALJA/62-152   AC U3EF87.1
#=GS E5RQ39_RAT/37-127     AC E5RQ39.1
#=GS F6TPS9_XENTR/62-152   AC F6TPS9.1
#=GS H3DQM5_TETNG/64-154   AC H3DQM5.1
#=GS W5PIS5_SHEEP/37-124   AC W5PIS5.1
#=GS B7ZSF1_XENLA/33-125   AC B7ZSF1.1
#=GS G1KJ78_ANOCA/62-152   AC G1KJ78.2
#=GS A1YF90_9PRIM/29-80    AC A1YF90.1
#=GS B0BNL3_RAT/61-151     AC B0BNL3.1
#=GS G1LY09_AILME/62-152   AC G1LY09.1
#=GS F1QUC6_DANRE/98-188   AC F1QUC6.1
#=GS G3R4Y7_GORGO/68-165   AC G3R4Y7.1
#=GS H2P937_PONAB/62-152   AC H2P937.1
#=GS F6VAF2_MACMU/37-124   AC F6VAF2.1
#=GS G1LY17_AILME/62-152   AC G1LY17.1
#=GS H9G2D8_MACMU/37-127   AC H9G2D8.1
#=GS G9K3X7_MUSPF/67-155   AC G9K3X7.1
#=GS L8HXE5_9CETA/56-146   AC L8HXE5.1
#=GS L5M2P1_MYODS/110-200  AC L5M2P1.1
#=GS F6X9B0_HORSE/61-149   AC F6X9B0.1
#=GS H3CU09_TETNG/64-154   AC H3CU09.1
#=GS G1SVG4_RABIT/69-157   AC G1SVG4.2
#=GS R0LBB7_ANAPL/56-145   AC R0LBB7.1
#=GS G1RSV2_NOMLE/62-152   AC G1RSV2.2
#=GS C9JD56_HUMAN/6-93     AC C9JD56.1
#=GS HDAC4_CHICK/62-151    AC P83038.1
#=GS Q4RHX0_TETNG/32-127   AC Q4RHX0.1
#=GS E5RQ38_RAT/37-127     AC E5RQ38.1
#=GS Q75N08_HUMAN/37-124   AC Q75N08.1
#=GS S7P7V4_MYOBR/86-164   AC S7P7V4.1
#=GS H3B8Y5_LATCH/49-150   AC H3B8Y5.1
#=GS F6XQL9_CALJA/51-141   AC F6XQL9.1
#=GS W5N050_LEPOC/34-124   AC W5N050.1
#=GS M4AHC6_XIPMA/66-164   AC M4AHC6.1
#=GS HDAC4_MOUSE/61-151    AC Q6NZM9.1
#=GS H0WX84_OTOGA/34-124   AC H0WX84.1
#=GS F6VAD3_MACMU/37-127   AC F6VAD3.1
#=GS G3UN27_LOXAF/37-123   AC G3UN27.1
#=GS H2UTM9_TAKRU/37-136   AC H2UTM9.1
#=GS K7FZ10_PELSI/34-124   AC K7FZ10.1
#=GS B7ZDF7_MOUSE/67-155   AC B7ZDF7.1
#=GS F7G734_MONDO/68-156   AC F7G734.2
#=GS HDAC4_RAT/61-151      AC Q99P99.2
#=GS Q53SM2_HUMAN/30-120   AC Q53SM2.1
#=GS HDAC9_CHICK/37-127    AC Q5ZKH6.1
#=GS K7CKK4_PANTR/62-152   AC K7CKK4.1
#=GS W5L1S7_ASTMX/67-157   AC W5L1S7.1
#=GS U3JMK1_FICAL/27-72    AC U3JMK1.1
#=GS K7GJR1_PELSI/62-152   AC K7GJR1.1
#=GS F6XF13_HORSE/62-150   AC F6XF13.1
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G1P6Y3_MYOLU/68-156              ...................................VDPALREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQ...........QQQMLA..........AKRQQE-LE..QQRQ....REQQ.........RQE-....E.LEKQRLEQQL..........................................
D2H1I0_AILME/33-120              ...................................VDPVVREKQLQQELLLIQQQQQIQKQLLIAEFQKQHENLTRQHQAQLQEHIK-...........--ELLA..........IKQQQELLE..KEQK....LEQQ.........RQEQ....E.VERHRREQQL..........................................
I3J443_ORENI/66-161              ...................................SDPGLWERQLQQELLLIQKQQQIQKQLLISEFQKQHEKLTRQHQAQLQEHLKL...........QQELQA..........MKQQQELAE..KERR....LEQQqq....qqsQQEK....E.QEKHRREHHI..........................................
Q4S076_TETNG/2-90                ...................................VDTTMREQQLQQELVLLKQQQELQKQMLFAEFQKKHEVLTRQHEVQLQEHLKQ...........QQELLA..........AKRQQE-LE..QKRK....LEQQ.........RHE-....E.QEKHRLEQQL..........................................
#=GC SS_cons                     ..................................---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH...........HHHHHH..........HHHCTGGG-..XXXX....XXXX.........XXXX....X.XXXXXXXXXX..........................................
#=GC seq_cons                    ....................................DPslREpQLQQELLhLKQQQQlQKQLLIAEFQKQHEpLTRQHEAQLQEHlK............QQEhLA..........hK+QQELLE..+pRK....lEQp.........RQEp....E.lE+p+REQpL..........................................
//
DBGET integrated database retrieval system