GenomeNet

Database: Pfam
Entry: HTH_15
LinkDB: HTH_15
Original site: HTH_15 
#=GF ID   HTH_15
#=GF AC   PF12324.6
#=GF DE   Helix-turn-helix domain of alkylmercury lyase
#=GF AU   Bateman A, Gavin OL
#=GF SE   Pfam-B_3505 (release 6.5)
#=GF GA   26.00 26.00;
#=GF TC   26.10 26.30;
#=GF NC   25.90 25.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Helix-turn-helix
#=GF DR   INTERPRO; IPR024259;
#=GF CC   Alkylmercury lyase (EC:4.99.1.2) cleaves the carbon-mercury bond
#=GF CC   of organomercurials such as phenylmercuric acetate. This is the
#=GF CC   N terminal helix-turn-helix domain associated with Pfam:PF03243.
#=GF SQ   36
#=GS D6U649_9CHLR/7-77         AC D6U649.1
#=GS E2SED0_9ACTN/3-75         AC E2SED0.1
#=GS G2G622_9ACTN/5-78         AC G2G622.1
#=GS F4CKR9_PSEUX/7-80         AC F4CKR9.1
#=GS G8MQ32_9BURK/2-74         AC G8MQ32.1
#=GS A4A3F8_9GAMM/5-75         AC A4A3F8.1
#=GS I7IXG7_9CORY/3-75         AC I7IXG7.1
#=GS A0A0D5V3J2_9BURK/5-78     AC A0A0D5V3J2.1
#=GS A0A0M2K6C8_9MYCO/7-78     AC A0A0M2K6C8.1
#=GS A0A077HKA5_9CORY/3-75     AC A0A077HKA5.1
#=GS A0A097IGF9_9CORY/3-75     AC A0A097IGF9.1
#=GS A0A0M8NNU5_9EURO/12-80    AC A0A0M8NNU5.1
#=GS G2GNS4_9ACTN/5-78         AC G2GNS4.1
#=GS A0A072TFB1_MEDTR/752-825  AC A0A072TFB1.1
#=GS F2G325_ALTMD/9-81         AC F2G325.1
#=GS U4L7Y8_PYROM/62-133       AC U4L7Y8.1
#=GS D0L7Y2_GORB4/6-74         AC D0L7Y2.1
#=GS F3NQD4_9ACTN/7-80         AC F3NQD4.1
#=GS G8MQ18_9BURK/7-79         AC G8MQ18.1
#=GS C7NGB6_KYTSD/13-83        AC C7NGB6.1
#=GS F2G337_ALTMD/5-75         AC F2G337.2
#=GS Q0AM71_MARMM/5-80         AC Q0AM71.1
#=GS A0A0D5V4V3_9BURK/5-78     AC A0A0D5V4V3.1
#=GS A0A0F0LWT7_9MICO/5-75     AC A0A0F0LWT7.1
#=GS A4V7U8_PSEFS/5-77         AC A4V7U8.1
#=GS A0A0F7N5V0_9ACTN/7-78     AC A0A0F7N5V0.1
#=GS D3PUY2_STANL/7-80         AC D3PUY2.1
#=GS A1TX80_MARHV/5-75         AC A1TX80.1
#=GS D4YL19_9MICO/3-76         AC D4YL19.1
#=GS B5EAP1_GEOBB/5-72         AC B5EAP1.1
#=GS B8HJ65_ARTCA/5-75         AC B8HJ65.1
#=GS B2I418_MYCMM/7-79         AC B2I418.1
#=GS L7LNN2_9ACTN/5-76         AC L7LNN2.1
#=GS B1MAE1_MYCA9/7-79         AC B1MAE1.1
#=GS A0A0M8VCX8_9ACTN/7-80     AC A0A0M8VCX8.1
#=GS H5TWU8_9ACTN/4-74         AC H5TWU8.1
D6U649_9CHLR/7-77                    dllathlaaqldctqdvac-----------------------QQILRGLAEtGQPLAPMDVASRLQIRLESLATYLAHAP..DMEFDNEGNIVGWG.
E2SED0_9ACTN/3-75                    ...................DLSSQLPQRLTRPEETGLDAGLLIPLLRLLVD.GDAVTVEELAAAAGRTLEEVRRGLAAVP..DTEYD-QGRIIGQG.
G2G622_9ACTN/5-78                    ................trk-LATRFTDTV--NRAPGVKLSLLRPLLTLLAS.GEPVTLDQLAAQADRTVDEIRQALADMP..DTEYDTAGRIIGNG.
F4CKR9_PSEUX/7-80                    ...................QLVAQLADALYGTGHPATQPWLFRPLLRLLAE.GEPVTLDRLAEAAGTSVDQVRQALAAEP..DTEYDADGRVVGLG.
G8MQ32_9BURK/2-74                    ..............klapy-----ILERLTPTNRPKGFAEFLVALLGELAK.GRPISRTTLARTLGWPAEQVAAVLEQAT..STEYDNDGNIIGY-.
A4A3F8_9GAMM/5-75                    .........deiverlglt---------------GEREAALHVTLLRELAL.GQPVTVERLAKSLNWTTDEAELVLEKLPcgTIEYDGQGRLIGYG.
I7IXG7_9CORY/3-75                    ............atdqalt--------YLLSPARSGIDPELFVPLLRLLAE.GEPVTVAELATASGRSEDTVRQGLAAVP..DTEYDDEGRIIGL-a
A0A0D5V3J2_9BURK/5-78                ..................r-YTAELVDRLTMAFRSEGLEELFVVLLRELAR.GRPVSRGTLALALDWPVERVAAVLQQAV..STEWDDDGNVVGYG.
A0A0M2K6C8_9MYCO/7-78                .......tvvstmdsvfsr------------QDS--PAGWLWQPLLRQLAR.GEPLTIADLAAATGRAGDEVAQAVGRLR..DTEYDDAGRIVGYG.
A0A077HKA5_9CORY/3-75                ............atdqalt--------YLLSPARSGIDPELFVPLLRLLAE.GEPVTVAELATASGRSEDTVRQGLAAVP..DTEYDDEGRIIGL-a
A0A097IGF9_9CORY/3-75                ............atdqalt--------YLLSPARSGIDPELFVPLLRLLAE.GEPVTVAELATASGRSEDTVRQGLAAVP..DTEYDDEGRIIGL-a
A0A0M8NNU5_9EURO/12-80               .....eqlknqlladmmai-------------------PAFFPALLRLVSR.GEPVPIAALATEVHIPIHDIEQWLRQQP..GTDWDSQGRLLGFG.
G2GNS4_9ACTN/5-78                    .......tqnlaarftdtv------------NRAPGVKLWLLRPLLTLLAT.GEPVTVDQLAAQAGRTVDEIREALADMA..DTEYDTQGRIIGNG.
A0A072TFB1_MEDTR/752-825             ................rht---AELVERLAMANQLEGFADLFVVLLRELSK.GAPVSPAALALALDWPIERVSVALEQAV..STEWDDYGNVVGYG.
F2G325_ALTMD/9-81                    ..................r-YLTKIAESLTPANQPQGFGELFVVLLRELAK.GRPVSRTTLAKSLDWPAQQVNAVLERTT..STEYDSDGNIVGY-.
U4L7Y8_PYROM/62-133                  ...................ELVTLFDQN--KGEGGGSMKWLFRPLLQMLTK.GEPVTVEDIATTTGKPLDEVKDILSTLS..SVELDEQGRVVGFG.
D0L7Y2_GORB4/6-74                    ..........ipadvfati-------------APADRDRALLRAALRLLAH.GAPVTVTELAAAAGVDAGDLEET-PIGA..DIEYDEQGRVLGWG.
F3NQD4_9ACTN/7-80                    ..................k-LADRLTAALGGGENVTGQPWLWRPLLQLLAT.GRPVTTGQLATATSHTEDDVRHALAAMP..DTEYDGTGRIIGSG.
G8MQ18_9BURK/7-79                    .................sp---TTYIEHFPSISRSQDSAELLVALLRELAK.GRPVSRTTLAGILNWPDERIAAVLAQTA..STEYDDDGNIIGHG.
C7NGB6_KYTSD/13-83                   ................sdl--SMQLPERLSRL----GETGLLIPLLRLLAD.GDPVTVQQLSVAAGRTIDEVRLGLAAMQ..DTEYDDQGRIVGQG.
F2G337_ALTMD/5-75                    .........deiverlglt---------------GEREAALHVTLLRELAL.GQPVTVERLAKSLNWTTDEAELVLEKLPcgTIEYDGQGRLIGSG.
Q0AM71_MARMM/5-80                    ......aqitavleagyig-------------ENPKDLQRASLYIYRALAS.GKPISIASIAEHLGTPLETASRLLNLVPpsAIELDDDGHIIGF-v
A0A0D5V4V3_9BURK/5-78                ..................r-YAAELVERLTMANQLEGFADLFVVLLRELSK.GAPVSPAALALALDWPVGRVTAALAQAV..STEWDDDGNVVGYG.
A0A0F0LWT7_9MICO/5-75                ................paa-----ITDRL-ATAETGLEIWLWLPLLKLLAE.GEPVTIADLATATGRTADEVQAALAAVP..DTEYDDEGQIIGQG.
A4V7U8_PSEFS/5-77                    ..................r-YITEIAERLTPTNRPKGFAEFLVALLGELAK.GRPISRTTLARTLGWPAEQVAAVLEQAT..STEYDNDGNIIGY-.
A0A0F7N5V0_9ACTN/7-78                ..................a-FAARFTTSL--GNAPGLTMPLLRPLLTLLAT.REPVTISQLAEHAGRSEEDIRHTLACMP..DTEYDTQGRIIGFG.
D3PUY2_STANL/7-80                    ...................RFDTWLSTSLADSEVGGGAWTIARSIQKLLLD.GKPVPVAGLAAETGRSVEEVEQALEAMP..SVEREPDGTVVGFG.
A1TX80_MARHV/5-75                    .........deiverlglt---------------GEREAALHVTLLRELAL.GQPVTVERLAKSLNWTTDEAELVLEKLPcgTIEYDGQGRLIGSG.
D4YL19_9MICO/3-76                    ...................ELTTQLPERLNNTEETGLDAVLLIPLLRLIVE.GGPVTVEQFAAAAGRPVDAVRTGLAAVP..DTEYDDQGRIIGQG.
B5EAP1_GEOBB/5-72                    ...tlhdvlaglhcdhprv----------------------WLFLLRALAK.GRPVSRTTIANALNSSLSEIEAALASFA..DTVYDEKGDVVACG.
B8HJ65_ARTCA/5-75                    ................ish-----VTERL-ATGETGMQPWLWLPLMKLLAL.GDPVDIADLAAATGRPVEEIRAALEAMA..DTEYDGSGRIVGQG.
B2I418_MYCMM/7-79                    ...................QLAHRLNDSL-GGDNPGSTPWMLRPLLDLLAH.GAPVTIDQLADATATTVEQVRHALTAMS..DTEYDEHGRIIGSG.
L7LNN2_9ACTN/5-76                    ............dektlay---------LLSPSRSGLDPSLFVPLLRLLAE.GEPVTIAELATASGRSENTVRRGLSSVP..DAEYDDDGRILGL-a
B1MAE1_MYCA9/7-79                    ...................QLAHRLNDSL-GGDNPGSTPWMLRPLLDLLAH.GAPVTIDQLADATATTVEQVRHALTAMS..DTEYDEHGRIIGSG.
A0A0M8VCX8_9ACTN/7-80                ..................k-LADRLTAALGGGENVTGQPWLWRPLLQLLAT.GRPVTTGQLATATSHTEDDVRHALAAMP..DTEYDETGRIIGSG.
H5TWU8_9ACTN/4-74                    ..............dnlta-------DVFAKILPAGRDRALMRAALRLLAH.GTPVTVTELAAAAGVPDLDPAQT-PIGA..DVEYDEAGRIVGWG.
#=GC seq_cons                        ..................h.......t.L..stpsthpstLhhsLLRhLAc.GcPVTlspLAsusupsh-cVcpsLsths..DTEYDspGRIlGhG.
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