GenomeNet

Database: Pfam
Entry: Helicase_RecD
LinkDB: Helicase_RecD
Original site: Helicase_RecD 
#=GF ID   Helicase_RecD
#=GF AC   PF05127.9
#=GF DE   Helicase
#=GF PI   DUF699;
#=GF AU   Bateman A, Eberhardt R
#=GF SE   Pfam-B_884 (release 7.7)
#=GF GA   22.40 22.40;
#=GF TC   22.40 22.40;
#=GF NC   22.30 22.30;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Domain
#=GF WK   Domain_of_unknown_function
#=GF RN   [1]
#=GF RM   19322199
#=GF RT   RNA helicase module in an acetyltransferase that modifies a
#=GF RT   specific tRNA anticodon.
#=GF RA   Chimnaronk S, Suzuki T, Manita T, Ikeuchi Y, Yao M, Suzuki T,
#=GF RA   Tanaka I;
#=GF RL   EMBO J. 2009;28:1362-1373.
#=GF RN   [2]
#=GF RM   15538360
#=GF RT   Crystal structure of RecBCD enzyme reveals a machine for
#=GF RT   processing DNA breaks.
#=GF RA   Singleton MR, Dillingham MS, Gaudier M, Kowalczykowski SC,
#=GF RA   Wigley DB;
#=GF RL   Nature. 2004;432:187-193.
#=GF DR   INTERPRO; IPR007807;
#=GF CC   This domain contains a P-loop (Walker A) motif, suggesting that
#=GF CC   it has ATPase activity, and a Walker B motif. In tRNA(Met)
#=GF CC   cytidine acetyltransferase (TmcA) it may function as an RNA
#=GF CC   helicase motor (driven by ATP hydrolysis) which delivers the
#=GF CC   wobble base to the active centre of the GCN5-related
#=GF CC   N-acetyltransferase (GNAT) domain [1]. It is found in the
#=GF CC   bacterial exodeoxyribonuclease V alpha chain (RecD), which has
#=GF CC   5'-3' helicase activity. It is structurally similar to the motor
#=GF CC   domain 1A in other SF1 helicases [2].
#=GF SQ   1317
#=GS B9H5L1_POPTR/285-483    AC B9H5L1.1
#=GS E8H4V5_ECO57/196-337    AC E8H4V5.1
#=GS EX5A_BUCAP/171-372      AC Q8K9A8.1
#=GS E1ZAA5_CHLVA/219-431    AC E1ZAA5.1
#=GS H2IY24_RAHAC/193-237    AC H2IY24.1
#=GS E9XK73_ECOLX/196-337    AC E9XK73.1
#=GS E1J3E4_ECOLX/196-337    AC E1J3E4.1
#=GS G8WEZ8_KLEOK/193-334    AC G8WEZ8.1
#=GS F9TN32_9VIBR/193-360    AC F9TN32.1
#=GS G8W3K3_KLEPN/194-240    AC G8W3K3.1
#=GS E7TDP1_SHIFL/196-337    AC E7TDP1.1
#=GS Q7N3J1_PHOLL/192-338    AC Q7N3J1.1
#=GS E1I5K5_ECOLX/196-337    AC E1I5K5.1
#=GS F4ANV5_GLAS4/206-363    AC F4ANV5.1
#=GS H5FHI2_ECOLX/196-337    AC H5FHI2.1
#=GS C4XBU5_KLEPN/234-335    AC C4XBU5.1
#=GS Q6LFR2_PHOPR/189-355    AC Q6LFR2.1
#=GS B5PA55_SALET/196-337    AC B5PA55.1
#=GS B8N1C7_ASPFN/282-499    AC B8N1C7.1
#=GS Q7RFX8_PLAYO/367-568    AC Q7RFX8.1
#=GS G7FWJ5_9GAMM/197-357    AC G7FWJ5.1
#=GS F9BUQ5_VIBCL/178-344    AC F9BUQ5.1
#=GS D2PD55_SULID/235-408    AC D2PD55.1
#=GS E7QJW8_YEASZ/190-403    AC E7QJW8.1
#=GS E9VRQ3_ECOLX/196-337    AC E9VRQ3.1
#=GS A7F2K3_SCLS1/283-500    AC A7F2K3.1
#=GS E2KQS8_ECO57/196-337    AC E2KQS8.1
#=GS A1RUG8_PYRIL/244-424    AC A1RUG8.1
#=GS E8DVB9_SALMO/196-337    AC E8DVB9.1
#=GS F0ULG2_AJEC8/282-498    AC F0ULG2.1
#=GS F7TIZ5_PASMD/183-334    AC F7TIZ5.1
#=GS F9H3W6_HAEHA/161-309    AC F9H3W6.1
#=GS Q1R8Q3_ECOUT/196-337    AC Q1R8Q3.1
#=GS C2DV51_ECOLX/196-337    AC C2DV51.1
#=GS H2IY24_RAHAC/229-339    AC H2IY24.1
#=GS F9T968_9VIBR/176-342    AC F9T968.1
#=GS G7TVJ2_VIBCL/209-375    AC G7TVJ2.1
#=GS B8MH63_TALSN/282-498    AC B8MH63.1
#=GS D4BT38_PRORE/192-338    AC D4BT38.1
#=GS D3B5A9_POLPA/333-441    AC D3B5A9.1
#=GS H9FWL8_MACMU/281-488    AC H9FWL8.1
#=GS B3II93_ECOLX/196-337    AC B3II93.1
#=GS Q4YXL9_PLABA/299-500    AC Q4YXL9.1
#=GS A4NKS7_HAEIF/161-207    AC A4NKS7.1
#=GS H5HSF0_ECOLX/196-337    AC H5HSF0.1
#=GS H5AXZ7_ECOLX/196-337    AC H5AXZ7.1
#=GS Q74SD6_YERPE/195-341    AC Q74SD6.1
#=GS A3M082_PICST/280-491    AC A3M082.2
#=GS B3DLS4_XENLA/2-37       AC B3DLS4.1
#=GS G1Z852_ECOLX/196-337    AC G1Z852.1
#=GS Q14W38_9VIRU/169-307    AC Q14W38.1
#=GS A4SIB4_AERS4/191-351    AC A4SIB4.1
#=GS B0BNX7_ACTPJ/154-303    AC B0BNX7.1
#=GS Q4N5N9_THEPA/277-464    AC Q4N5N9.1
#=GS G7NDL8_MACMU/281-461    AC G7NDL8.1
#=GS F9CKF3_ECOLX/196-337    AC F9CKF3.1
#=GS F2FDI1_SALDU/196-337    AC F2FDI1.1
#=GS H5LP13_ECOLX/196-337    AC H5LP13.1
#=GS Q582B4_TRYB2/304-501    AC Q582B4.1
#=GS E0WS65_9ENTR/204-350    AC E0WS65.1
#=GS E9ID92_SOLIN/241-448    AC E9ID92.1
#=GS C4SMZ0_YERFR/201-347    AC C4SMZ0.1
#=GS H9KK29_APIME/277-325    AC H9KK29.1
#=GS E1EE48_VIBPA/176-343    AC E1EE48.1
#=GS C4UX78_YERRO/194-340    AC C4UX78.1
#=GS G5N0I3_SALET/196-337    AC G5N0I3.1
#=GS G2FDA5_9GAMM/208-375    AC G2FDA5.1
#=GS H8DBF3_ECOLX/196-337    AC H8DBF3.1
#=GS A8QCS2_BRUMA/280-484    AC A8QCS2.1
#=GS TMCA_YERE8/185-331      AC A1JL12.1
#=GS C9SQW2_VERA1/283-499    AC C9SQW2.1
#=GS G4D951_9GAMM/238-395    AC G4D951.1
#=GS D5CWR6_ECOKI/196-337    AC D5CWR6.1
#=GS G7B2P8_VIBCL/178-344    AC G7B2P8.1
#=GS F9QVQ2_ECOLX/196-337    AC F9QVQ2.1
#=GS F6XK43_CALJA/281-490    AC F6XK43.1
#=GS D3RRX5_ALLVD/219-389    AC D3RRX5.1
#=GS F8D6B2_HALXS/232-403    AC F8D6B2.1
#=GS D9P4K4_ACTPL/158-307    AC D9P4K4.1
#=GS E2WZQ1_ECOLX/196-337    AC E2WZQ1.1
#=GS D0II04_9VIBR/175-341    AC D0II04.1
#=GS G5G5Q5_HAEAP/177-328    AC G5G5Q5.1
#=GS Q3IPL4_NATPD/222-394    AC Q3IPL4.1
#=GS H5KWT7_ECOLX/196-337    AC H5KWT7.1
#=GS F5PU44_SHIFL/196-337    AC F5PU44.1
#=GS F4URJ1_ECOLX/196-337    AC F4URJ1.1
#=GS F4SHI8_ECOLX/196-337    AC F4SHI8.1
#=GS G5VS71_ECOLX/196-337    AC G5VS71.1
#=GS G9U406_SALMO/196-337    AC G9U406.1
#=GS E4WRH7_OIKDI/280-474    AC E4WRH7.1
#=GS E7V3F0_SALTM/196-337    AC E7V3F0.1
#=GS A9YK41_DROSI/19-204     AC A9YK41.1
#=GS A3GIK1_VIBCL/209-375    AC A3GIK1.1
#=GS F7RBS5_SHIFL/196-337    AC F7RBS5.1
#=GS E8YAH7_ECOKO/196-337    AC E8YAH7.1
#=GS D7YD56_ECOLX/196-337    AC D7YD56.1
#=GS H5NBV6_ECOLX/196-337    AC H5NBV6.1
#=GS Q96Y10_SULTO/226-404    AC Q96Y10.1
#=GS G0WCV1_NAUDC/280-497    AC G0WCV1.1
#=GS A4NAT1_HAEIF/161-309    AC A4NAT1.1
#=GS H4FIV0_ECOLX/196-337    AC H4FIV0.1
#=GS TMCA_SHIF8/196-337      AC Q0T243.1
#=GS A7UW96_NEUCR/446-661    AC A7UW96.1
#=GS Q4PF95_USTMA/292-503    AC Q4PF95.1
#=GS A4NRH1_HAEIF/161-309    AC A4NRH1.1
#=GS G9ZAW3_9ENTR/196-337    AC G9ZAW3.1
#=GS C1M7V2_9ENTR/196-337    AC C1M7V2.1
#=GS G9RK32_9ENTR/194-240    AC G9RK32.1
#=GS B4TD60_SALHS/196-337    AC B4TD60.1
#=GS Q74MW6_NANEQ/249-421    AC Q74MW6.1
#=GS H5M456_ECOLX/196-337    AC H5M456.1
#=GS E8ANC6_SALMO/196-337    AC E8ANC6.1
#=GS D7ZUC9_ECOLX/196-337    AC D7ZUC9.1
#=GS A3J8G5_9ALTE/241-410    AC A3J8G5.1
#=GS F6JKJ6_DROSI/19-204     AC F6JKJ6.1
#=GS H1R5M4_VIBFI/192-362    AC H1R5M4.1
#=GS B4TR57_SALSV/196-337    AC B4TR57.1
#=GS Q8FF79_ECOL6/196-337    AC Q8FF79.1
#=GS Q3YZ78_SHISS/196-337    AC Q3YZ78.1
#=GS F1XMU8_ECO57/196-337    AC F1XMU8.1
#=GS I0NFT9_SALET/196-337    AC I0NFT9.1
#=GS G8BXL6_TETPH/280-492    AC G8BXL6.1
#=GS F9RW13_9VIBR/199-370    AC F9RW13.1
#=GS E9U268_ECOLX/196-337    AC E9U268.1
#=GS E4WRH7_OIKDI/794-988    AC E4WRH7.1
#=GS B4EY73_PROMH/194-339    AC B4EY73.1
#=GS E9CEN1_CAPO3/279-478    AC E9CEN1.1
#=GS B9WLM6_CANDC/280-490    AC B9WLM6.1
#=GS E9AR97_LEIMU/288-480    AC E9AR97.1
#=GS A9MHQ6_SALAR/196-337    AC A9MHQ6.1
#=GS A3QMK2_9VIRU/238-377    AC A3QMK2.1
#=GS G7RPZ4_ECOC1/196-337    AC G7RPZ4.1
#=GS D4GW73_HALVD/230-401    AC D4GW73.1
#=GS B0WP12_CULQU/276-438    AC B0WP12.1
#=GS D2ZF96_9ENTR/186-327    AC D2ZF96.1
#=GS Q2SKZ4_HAHCH/221-384    AC Q2SKZ4.1
#=GS I1E2D6_9GAMM/206-365    AC I1E2D6.1
#=GS E8D5C5_SALMO/196-337    AC E8D5C5.1
#=GS A8A8R1_IGNH4/250-430    AC A8A8R1.1
#=GS C8U7Z5_ECO10/196-337    AC C8U7Z5.1
#=GS H4JQ91_ECOLX/196-337    AC H4JQ91.1
#=GS TMCA_METKA/280-456      AC Q8TYZ5.1
#=GS F7WAS0_SORMK/281-496    AC F7WAS0.1
#=GS F4N5P7_YEREN/195-341    AC F4N5P7.1
#=GS B7VPX6_VIBSL/189-357    AC B7VPX6.1
#=GS F4M6R8_ECOLX/196-337    AC F4M6R8.1
#=GS A5DAN3_PICGU/280-490    AC A5DAN3.1
#=GS B3A8W6_ECO57/196-337    AC B3A8W6.1
#=GS E7IUY2_ECOLX/196-337    AC E7IUY2.1
#=GS Q0CUS5_ASPTN/282-498    AC Q0CUS5.1
#=GS TMCA_VIBCH/209-375      AC Q9KKJ5.1
#=GS D8BQN6_ECOLX/196-337    AC D8BQN6.1
#=GS G4JRJ8_9CREN/262-441    AC G4JRJ8.1
#=GS C5B7A5_EDWI9/191-335    AC C5B7A5.1
#=GS D3QM53_ECOCB/196-337    AC D3QM53.1
#=GS G3RF58_GORGO/281-488    AC G3RF58.1
#=GS E8XGH6_SALT4/196-337    AC E8XGH6.1
#=GS C3LX22_VIBCM/209-375    AC C3LX22.1
#=GS E8IB42_ECOLX/196-337    AC E8IB42.1
#=GS Q4UDV5_THEAN/277-464    AC Q4UDV5.1
#=GS F8QCK0_SERL3/276-468    AC F8QCK0.1
#=GS G2QK54_THIHA/282-497    AC G2QK54.1
#=GS G4AG50_AGGAC/3-154      AC G4AG50.1
#=GS G6ZMX1_VIBCL/178-344    AC G6ZMX1.1
#=GS F2DH58_HORVD/280-477    AC F2DH58.1
#=GS C0AKJ8_BORBG/213-330    AC C0AKJ8.1
#=GS G0EGD6_PYRF1/291-472    AC G0EGD6.1
#=GS C4F0C6_HAEIF/161-309    AC C4F0C6.1
#=GS E8B9R6_SALMO/196-337    AC E8B9R6.1
#=GS F6DB94_THICA/243-395    AC F6DB94.1
#=GS F6SDN4_HORSE/117-324    AC F6SDN4.1
#=GS D7LWH6_ARALL/36-167     AC D7LWH6.1
#=GS F2SUN9_TRIRC/282-500    AC F2SUN9.1
#=GS H5HA79_ECOLX/196-337    AC H5HA79.1
#=GS F4UBX2_ECOLX/196-337    AC F4UBX2.1
#=GS Q1CK21_YERPN/195-341    AC Q1CK21.1
#=GS H8NXM7_RAHAQ/193-339    AC H8NXM7.1
#=GS A6F0M7_9ALTE/208-378    AC A6F0M7.1
#=GS H1EEU3_ECOLX/196-337    AC H1EEU3.1
#=GS F6Y8C3_CIOIN/280-479    AC F6Y8C3.2
#=GS H1FJI6_ECOLX/196-337    AC H1FJI6.1
#=GS Q4QE66_LEIMA/288-480    AC Q4QE66.1
#=GS G9W7X4_SALET/196-337    AC G9W7X4.1
#=GS Q57LM6_SALCH/196-337    AC Q57LM6.1
#=GS Q4XQN8_PLACH/207-286    AC Q4XQN8.1
#=GS G0S273_CHATD/282-497    AC G0S273.1
#=GS Q9Y993_AERPE/250-429    AC Q9Y993.2
#=GS D0HQ32_VIBCL/178-344    AC D0HQ32.1
#=GS D6ISJ0_ECOLX/196-337    AC D6ISJ0.1
#=GS A0KPS8_AERHH/191-351    AC A0KPS8.1
#=GS E8XP32_RAHSY/193-339    AC E8XP32.1
#=GS E0E7H7_ACTPL/158-307    AC E0E7H7.1
#=GS D5C6Z4_ENTCC/186-327    AC D5C6Z4.1
#=GS F0KRJ0_YERE3/195-341    AC F0KRJ0.1
#=GS Q4YJ54_PLABA/1-161      AC Q4YJ54.1
#=GS H5MIH7_ECOLX/196-337    AC H5MIH7.1
#=GS B2P3S9_ECO57/196-337    AC B2P3S9.1
#=GS TMCA_PHOAA/192-338      AC C7BGY4.1
#=GS B5IH80_ACIB4/219-385    AC B5IH80.1
#=GS Q32D93_SHIDS/196-337    AC Q32D93.1
#=GS E2P3Y8_PASHA/166-315    AC E2P3Y8.1
#=GS B7NQL2_ECO7I/196-337    AC B7NQL2.1
#=GS F9GLR2_HAEHA/161-309    AC F9GLR2.1
#=GS G4G9T1_9EURY/231-400    AC G4G9T1.1
#=GS G3P5Z9_GASAC/283-490    AC G3P5Z9.1
#=GS H8ZF00_NEMS1/252-428    AC H8ZF00.1
#=GS E7YRT8_SALMO/196-337    AC E7YRT8.1
#=GS B7M7H5_ECO8A/196-337    AC B7M7H5.1
#=GS H8K2E7_VIBCL/178-344    AC H8K2E7.1
#=GS F9RHV0_9VIBR/199-370    AC F9RHV0.1
#=GS H5TBC4_9ALTE/210-381    AC H5TBC4.1
#=GS G0TVL6_TRYVI/286-484    AC G0TVL6.1
#=GS Q55HL6_CRYNB/280-498    AC Q55HL6.1
#=GS B4DFD5_HUMAN/209-416    AC B4DFD5.1
#=GS H5E517_ECOLX/196-337    AC H5E517.1
#=GS G2AXN3_ECOLX/196-337    AC G2AXN3.1
#=GS G9AN05_PANAN/190-235    AC G9AN05.1
#=GS B2AKV8_PODAN/299-514    AC B2AKV8.1
#=GS G0D774_ECOLX/196-337    AC G0D774.1
#=GS C3NGE3_SULIN/235-408    AC C3NGE3.1
#=GS G7ED52_9GAMM/197-357    AC G7ED52.1
#=GS C9QPV0_ECOD1/196-337    AC C9QPV0.1
#=GS E8F213_SALMO/196-337    AC E8F213.1
#=GS E9W311_ECOLX/196-337    AC E9W311.1
#=GS E7SGM5_SHIDY/196-337    AC E7SGM5.1
#=GS H4VZG2_ECOLX/196-337    AC H4VZG2.1
#=GS A6XR49_VIBCL/209-375    AC A6XR49.1
#=GS I0VFF9_SHIFL/196-337    AC I0VFF9.1
#=GS H4NA61_ECOLX/196-337    AC H4NA61.1
#=GS G8BFD3_CANPC/280-491    AC G8BFD3.1
#=GS I1BFK7_ECOLX/196-337    AC I1BFK7.1
#=GS E1C2J8_CHICK/281-451    AC E1C2J8.1
#=GS TMCA_ECOLI/196-337      AC P76562.1
#=GS TMCA_ECOLI/196-337      DR PDB; 2ZPA B; 196-337;
#=GS TMCA_ECOLI/196-337      DR PDB; 2ZPA A; 196-337;
#=GS F8PC32_SERL9/276-468    AC F8PC32.1
#=GS A9Z333_YERPE/195-341    AC A9Z333.1
#=GS E0SE32_DICD3/195-341    AC E0SE32.1
#=GS A6B3I3_VIBPA/176-343    AC A6B3I3.1
#=GS A4BT93_9GAMM/210-376    AC A4BT93.1
#=GS I0MLL2_SALET/196-337    AC I0MLL2.1
#=GS F4RWH0_MELLP/291-509    AC F4RWH0.1
#=GS D0X6Z0_VIBHA/193-360    AC D0X6Z0.1
#=GS C1H481_PARBA/282-498    AC C1H481.1
#=GS H4K5I2_ECOLX/196-337    AC H4K5I2.1
#=GS A2BLX9_HYPBU/222-391    AC A2BLX9.1
#=GS G1SFC6_RABIT/281-488    AC G1SFC6.1
#=GS G6ZKE1_VIBCL/178-344    AC G6ZKE1.1
#=GS Q2QX38_ORYSJ/1-112      AC Q2QX38.1
#=GS D4GK02_PANAM/190-235    AC D4GK02.1
#=GS B0D7J6_LACBS/277-496    AC B0D7J6.1
#=GS D8E2L1_ECOLX/196-337    AC D8E2L1.1
#=GS G7ISQ3_MEDTR/277-479    AC G7ISQ3.1
#=GS B3BV49_ECO57/196-337    AC B3BV49.1
#=GS F2UD48_SALS5/18-162     AC F2UD48.1
#=GS F7ST32_9GAMM/218-392    AC F7ST32.1
#=GS H3LRR0_KLEOX/193-334    AC H3LRR0.1
#=GS F2TMA4_AJEDA/282-498    AC F2TMA4.1
#=GS D8UF13_VOLCA/284-511    AC D8UF13.1
#=GS D2U229_9ENTR/181-327    AC D2U229.1
#=GS D0P0F5_PHYIT/281-517    AC D0P0F5.1
#=GS E8BUT5_SALMO/196-337    AC E8BUT5.1
#=GS H0N956_SALET/196-337    AC H0N956.1
#=GS G2CN90_ECOLX/196-337    AC G2CN90.1
#=GS H4SV30_ECOLX/196-337    AC H4SV30.1
#=GS B7MXX3_ECO81/196-337    AC B7MXX3.1
#=GS G7R332_ECOC2/196-337    AC G7R332.1
#=GS H5QHH9_ECOLX/196-337    AC H5QHH9.1
#=GS H5DMC3_ECOLX/196-337    AC H5DMC3.1
#=GS I0ABR3_SALET/196-337    AC I0ABR3.1
#=GS C9ME15_HAEIF/161-309    AC C9ME15.1
#=GS G2H167_9ENTR/199-345    AC G2H167.1
#=GS H2FT16_OCESG/201-348    AC H2FT16.1
#=GS B3YEV1_SALET/196-337    AC B3YEV1.1
#=GS G8ZPT3_TORDC/280-492    AC G8ZPT3.1
#=GS I1HNM0_BRADI/280-477    AC I1HNM0.1
#=GS F4G0V7_METCR/217-391    AC F4G0V7.1
#=GS G5R3H2_SALSE/196-337    AC G5R3H2.1
#=GS D3RKT8_KLEVT/194-335    AC D3RKT8.1
#=GS O51577_BORBU/213-330    AC O51577.1
#=GS E6AIU6_ECOLX/196-337    AC E6AIU6.1
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