GenomeNet

Database: Pfam
Entry: Herpes_DNAp_acc
LinkDB: Herpes_DNAp_acc
Original site: Herpes_DNAp_acc 
#=GF ID   Herpes_DNAp_acc
#=GF AC   PF04929.8
#=GF DE   Herpes DNA replication accessory factor 
#=GF AU   Finn RD
#=GF SE   Pfam-B_5837 (release 7.6)
#=GF GA   25.00 25.00;
#=GF TC   26.10 217.80;
#=GF NC   22.40 21.50;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 80369284 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10882068
#=GF RT   The crystal structure of an unusual processivity factor, herpes
#=GF RT   simplex virus UL42, bound to the C terminus of its cognate
#=GF RT   polymerase. 
#=GF RA   Zuccola HJ, Filman DJ, Coen DM, Hogle JM; 
#=GF RL   Mol Cell 2000;5:267-278.
#=GF RN   [2]
#=GF RM   9934686
#=GF RT   Identification of transactivator and nuclear localization
#=GF RT   domains in the Epstein-Barr virus DNA polymerase accessory
#=GF RT   protein, BMRF1. 
#=GF RA   Zhang Q, Holley-Guthrie E, Dorsky D, Kenney S; 
#=GF RL   J Gen Virol 1999;80:69-74.
#=GF DR   INTERPRO; IPR007013;
#=GF CC   Replicative DNA polymerases are capable of polymerising tens of
#=GF CC   thousands of nucleotides without dissociating from their DNA
#=GF CC   templates. The high processivity of these polymerases is
#=GF CC   dependent upon accessory proteins that bind to the catalytic
#=GF CC   subunit of the polymerase or to the substrate.  The Epstein-Barr
#=GF CC   virus (EBV) BMRF1 protein is an essential component of the viral
#=GF CC   DNA polymerase and is absolutely required for lytic virus
#=GF CC   replication [2]. BMRF1 is also a transactivator [2].  This
#=GF CC   family is predicted to have a UL42 like structure [1].
#=GF SQ   28
#=GS EAD_EBVG/4-404       AC Q3KSU3.1
#=GS Q77ZG5_HHV8/6-396    AC Q77ZG5.1
#=GS Q77ZG5_HHV8/6-396    DR PDB; 3I2M X; 6-300;
#=GS Q77ZG5_HHV8/6-396    DR PDB; 3HSL X; 6-300;
#=GS Q993F6_9GAMA/4-400   AC Q993F6.1
#=GS PAP_HHV8P/6-396      AC F5HID2.1
#=GS EAD_EBVA8/4-404      AC P0C6Z0.1
#=GS Q9WRN5_9GAMA/6-394   AC Q9WRN5.1
#=GS D0U1P8_MHV68/1-395   AC D0U1P8.1
#=GS VG59_ALHV1/4-408     AC O36409.1
#=GS VG59_SHV21/10-368    AC Q01052.1
#=GS G1EUL5_BHV4/6-391    AC G1EUL5.1
#=GS EAD_EBVB9/4-404      AC P03191.1
#=GS EAD_EBVB9/4-404      DR PDB; 2Z0L B; 4-299;
#=GS EAD_EBVB9/4-404      DR PDB; 2Z0L E; 4-299;
#=GS EAD_EBVB9/4-404      DR PDB; 2Z0L A; 4-299;
#=GS EAD_EBVB9/4-404      DR PDB; 2Z0L G; 4-299;
#=GS EAD_EBVB9/4-404      DR PDB; 2Z0L D; 4-299;
#=GS EAD_EBVB9/4-404      DR PDB; 2Z0L F; 4-299;
#=GS EAD_EBVB9/4-404      DR PDB; 2Z0L H; 4-299;
#=GS EAD_EBVB9/4-404      DR PDB; 2Z0L C; 4-299;
#=GS P88950_HHV8/6-396    AC P88950.1
#=GS Q9YTK8_ATHV3/10-320  AC Q9YTK8.1
#=GS Q77NI0_9GAMA/6-394   AC Q77NI0.1
#=GS U5NIG6_HHV8/6-400    AC U5NIG6.1
#=GS E9M5P2_9GAMA/2-421   AC E9M5P2.1
#=GS P88996_MHV68/1-393   AC P88996.1
#=GS Q80BM1_SHV2/10-371   AC Q80BM1.1
#=GS Q8UZI4_9GAMA/4-404   AC Q8UZI4.1
#=GS VG59_EHV2/8-414      AC Q66661.1
#=GS Q918P2_9GAMA/4-385   AC Q918P2.1
#=GS Q99CY3_BHV4/6-391    AC Q99CY3.1
#=GS Q53CV4_9GAMA/6-394   AC Q53CV4.1
#=GS K0FCA2_HHV8/6-386    AC K0FCA2.1
#=GS G3CKQ3_EBVG/4-404    AC G3CKQ3.1
#=GS K9UR48_EBVG/4-404    AC K9UR48.1
#=GS Q2VSI2_9GAMA/4-385   AC Q2VSI2.1
#=GS V5KUC5_EBVG/4-404    AC V5KUC5.1
EAD_EBVG/4-404                  ..TQTLRFKTKALAVLSKCYDHAQ.THLK.GGVLQVNLLSVNy...ggPRLAAVANAGTAGLISFEVSpDAVAEWQNHQSPEE......APAAVSFRN.LAYGRTCVLGKELFGSAVEQASLQFYKRPQG-..GSRP..EFVKLTMEYDDK.VSKSHHTCALM.PYMPP.ASDRLRNEQMIGQVLLMPKTASSLQKWARQQGSGG.-.-VKVTLNPDLYVTTYT.SGEACLTLDYK.....PLSVG..PYEAFTGpVAKAQ.DSGAVEAHVVCSVAADSLAAALSLCRIPAVSVPILRFYRSGIIAVVAGLLTSAGDLPLDLSVILFNHASEEAAASTASEPEDKsp......rvQPLGTGLQQRP.RHTVSPSPSp..pPPPRTPt.....wESPARP--------..---.................--------..ETPSP.AIPSHSSNTALErpl......avqlARKRTSSEARQKQKHPkkvKQAFNPLI...............................................................
Q77ZG5_HHV8/6-396               ..HYGVRVDVTLLSKIRRVNEHIK.SATK.TGVVQVHGSACT......PTLSVLSSVGTAGVLGLRIK.NALTPL-VGHTEGS......GDVSFSFRN.TSVGSGFTHTRELFGANVLDAGIAFYRKGEACdtGAQP..QFVRTTISYGDN.LTSTVHKSVVDqKGILP.FHDRMEAGGRTTRLLLCGKTGAFLLKWLRQQKTKE.DqTVTVSVSETLSIVTFS.LGGVSKIIDFK.....P-ETK..PVSGWDGlKGKKSvDVGVVHTDALSRVSLESLIAALRLCKVPGWFTPGLIWHSNEILEVEGVP-TGCQSGDVKLSVLLL----EVNRSVSAEGGESS..........QKVPDSIPDSR.RQPELESPD....SPPLTP.......VGPFGPLEDASEDA..ASV.................--------..TSCPP.AAPTKDSTKRPH.............KRRSDSSQSRDRGKVP...KTTFNPLI...............................................................
#=GR Q77ZG5_HHV8/6-396    SS    ..-EEEEE-HHHHHHHHHHHHHHH.HHHT.TSEEEEEEETTS......EEEEEEEE-TTSEEEEEEES.S-EEE--TT-TTTT......SEEEEEEES.B-TT-S-BHHHHHT-TTEEEEEEEEE-XXXXXXXXXX-..-EEEEEEEESST.T-EEEEEEE---TTS--.-TT-S-SSTT-EEEE--HHHHHHHHHHHHTT--SS.--EEEEEEETTTTEEEEE.ETTEEEEEE-E.....E--SS..--BTTBTTB-TTSS-EEE-SS-EEEEEEHHHHHHHHHHT-BTTTEEEEEEE-SSS-EEEEEEE-SSSTTTTEEEEEEE-------XXXXXXXXXXXX..........XXXXXXXXXXX.XXXXXXXXX....XXXXXX.......XXXXXXXXXXXXXX..XXX.................--------..XXXXX.XXXXXXXXXXXX.............XXXXXXXXXXXXXXXX...XXXXXXXX...............................................................
Q993F6_9GAMA/4-400              ..TQSLVFVPGALATLSKCYEHVQ.THLK.TGIIQVSLVGSLnsaqavPRFILSSNMLQTARLQFEVTeRAIAEWHNHQNEAD......SPATLSVRN.MAYGRTFLLARELFSHAVKEASFKFYRKTDG-..--GP..QFVRMILEYDDL.STMMHHTAVLE.PYVAP.FGDALSGERLVGRVLLSPKTTMGLQKFTRVRGAAP.-.-VRITLNPDLYVLTCIgEDDGCHTVDYK.....PVSVP..ARDSFATpITKAI.DSAAADSHVMSRAAANALCTALGLCRIPGVSVPILNFYESGLLCVSAALLTTASHLPLDLRVVLFNPSYKNDGDVHNPEAVKI..........QEEWPIRATVS.PKPCHLLTDisqsPPVCSPp.....hQ---T-----PLPA..LNS.................----ITEP..QEFAR.CVASTFQRKRN-.............CTEETVSKQKKPSKKL...KLSFNPLI...............................................................
PAP_HHV8P/6-396                 ..HYGVRVDVTLLSKIRRVNEHIK.SATK.TGVVQVHGSACT......PTLSVLSSVGTAGVLGLRIK.NALTPL-VGHTEGS......GDVSFSFRN.TSVGSGFTHTRELFGANVLDAGIAFYRKGEACdtGAQP..QFVRTTISYGDN.LTSTVHKSVVDqKGILP.FHDRMEAGGRTTRLLLCGKTGAFLLKWLRQQKTKE.DqTVTVSVSETLSIVTFS.LGGVSKIIDFK.....P-ETK..PVSGWDGlKGKKSvDVGVVHTDALSRVSLESLIAALRLCKVPGWFTPGLIWHSNEILEVEGVP-TGCQSGDVKLSVLLL----EVNRSVSAEGGESS..........QKVPDSIPDSR.RQPELESPD....SPPLTP.......VGPFGPLEDASEDA..ASV.................--------..TSCPP.AAPTKDSTKRPH.............KRRSDSSQSRDRGKVP...KTTFNPLI...............................................................
EAD_EBVA8/4-404                 ..TQTLRFKTKALAVLSKCYDHAQ.THLK.GGVLQVNLLSVNy...ggPRLAAVANAGTAGLISFEVSpDAVAEWQNHQSPEE......APAAVSFRN.LAYGRTCVLGKELFGSAVEQASLQFYKRPQG-..GSRP..EFVKLTMEYDDK.VSKSHHTCALM.PYMPP.ASDRLRNEQMIGQVLLMPKTASSLQKWARQQGSGG.-.-VKVTLNPDLYVTTYT.SGEACLTLDYK.....PLSVG..PYEAFTGpVAKAQ.DVGAVEAHVVCSVAADSLAAALSLCRIPAVSVPILRFYRSGIIAVVAGLLTSAGDLPLDLSVILFNHASEEAAASTASEPEDKsp......rvQPLGTGLQQRP.RHTVSPSPSp..pPPPRTPt.....wESPARP--------..---.................--------..ETPSP.AIPSHSSNTALErpl......avqlARKRTSSEARQKQKHPkkvKQAFNPLI...............................................................
Q9WRN5_9GAMA/6-394              ..HYGARVDVDALGSISRVYDHIK.GIVK.KGVIQISGQGRA......PVLSVLSSVGDAGVLGLRLK.NALAPLM-VYSDMT......DEVSFSFRN.TSLGNTFTHTREMFGVNIAEMNVAFYHHGDESdaEGKP..QFVRTTIAYGDN.HTSTVHKSVVDePNLPS.FHDRLEQAGTGNRLFLTVKTLTLLLKWLRQQKTRA.KqVVTVSLSETLAVATFT.VDGVSKIIDFK.....P--DT..PDAKWTCaRGRKL.DVGVVSSDLTTHVSLESLVAALNACKIPGFFLPGFRWHANEILEVEGLPLTDS-LADVRLGVMLLKVDPTDRNNAVPGN-LSE..........GADPEG-----.----VPELP....SPPRTPdldlkeqCVPIAE--DGAEPT..DGG.................--------..AKSLR.TSGSR-PEKKHG.............KRKHSSSPSRGKGKTKt.pRATFNPL-f..............................................................
D0U1P8_MHV68/1-395              .m-QTFQLDTDRLWQAAKLYQHTK.SDFGvNGMIQLSGSCNN......MSLSILGSIGGCAILRLELL.EAARLHSSKESSK-......-SAIYSFRNsSSLGREFTHGGELFGPKMESASLSFYGHHGV-..----..RYVEAQFV-HDS.SSKTVHTAAMQ.PITIP.PSCAFDDREARGIVTMSTKTAAALVKWLKQHTKTC.QsPVKVSISEILSVMVVS.VGDASMTVDVA.....PVNVS..SGKKTRG.GNRAS.DSGSISADATVHVNGHCLIRSLVVCKVPGCTTPRVKFHACGILEVDGAPVKQGELTQVKLSVALL--NVDCTT-----GKVLK..........EPVVTGSSKDR.VASASKSEDa.asSPPIQDh.....hQGSLTSDSDSSVPGprSSD.................LSSLTRTP.sDTFSS.DIRPGCGGQQFL.............KRPPPKKEKEPTPKRP...KLHFNH--f..............................................................
VG59_ALHV1/4-408                ..CASFRLSPALLTSSTKIYDHVK.SHLK.SAMIQFSDLNTT......PVMSIISNMGSAGIVTFQLT.GAVSDTE---TLAE......ITEPLAFRN.HSFGGTYLHSREFFGKEIEDILVRFYKRASTA..SKLP..EFVETKITYNNS.ITETRHTSTVD.SHVSP.VEKYLQKCFVKAKLILSIKTCTMLQKWLRQNKNKS.P.VARLHINETLTVLVVT.VGDECTTIEFK.....SFVLE..PADAFLT.LDKPG.NFGAVLVDCTAVVNLECLIQAIGICKVPSVCVPAFKFYSGGIVEVSSAHLKQSKSPSATVSTVLLDASESLKQPAEQEQPTTS..........QPSDPQSSNSV.DKPSPPRPSi..sQPVRRR.......APPRAIISDSEEDS..DSDsdqdc......stetqpETSYREEPkkFTPKP.TAPPN-------.............KRKQFEPLKCPVEKKK...KSNSNSFV...............................................................
VG59_SHV21/10-368               .s-YGVGFKPCVLQEHTKIYNHIK.AKVK.DGIIQIEGLTSS......PSLRIWSSIGE-GILSFKIN.NVVSEVFNCHMMPE......-NVSVSFRNiSPGGNTFLYTRELFGCNVKTATLMFSNR----..SGKP.fEFIKAKLEYCDK.VSTTRHTSTIP.AGILP.FVENVNSTSVLSRVVLSPKTAAMLQKWLREHKAHK.-.TVSVMVNSTLAVLILT.VEDSTKTVDLHivddmSLCNN..PSK----.-----.DWGVVQNDVQTKVNITALSAALGLCKIPGVFVPCIKFYESEVLEVCGTPVKLGSWVDTSLQVTLF---------CTPNLAEDT..........QAAVSD-----.---------....------.......YFPISP--------..---.................SACLTADPadTQEEP.TLSSNCQDSSVEnsp......alplKRKREK-DINKKSKKI...KIAFNPLI...............................................................
G1EUL5_BHV4/6-391               ..CYSANVKVPALTQNNKLYDHIK.NNLK.NGLIQLEGPSSG......PILSFLVNVGETGILVMKIK.DALEPMHEMDSPQEedlnksNNVSFSFRN.TSLGNTFVHSRELFGANVRDIYIVFYKR-ET-..SNVV..QFVRTTITYCDN.ETNTTHKSVVE.AQAMP.FIGKMETSEICSRVTLCPKTANALQKFLKQHKTKE.KrTVRVSINETLGVIIFT.IGEDSKTIDFK.....MSDQQ..DLEN-IQ.TAKVE.DVGHVNGDSVSYVSLESLTAALGCCKIPGCLTPCFRLYSSDILEVIGARLKGCTLGDSSISVILLKAEATEENNSTSIGNLDSisk...niceN----------.--R------....----GD.......KYPQPCKDEARSPS..TSV.................---EEERP..LTPSPpHCLSRPPNPTPV.............KRRHAD-LKKKNHKKL...RLSFTPLI...............................................................
EAD_EBVB9/4-404                 ..TQTLRFKTKALAVLSKCYDHAQ.THLK.GGVLQVNLLSVNy...ggPRLAAVANAGTAGLISFEVSpDAVAEWQNHQSPEE......APAAVSFRN.LAYGRTCVLGKELFGSAVEQASLQFYKRPQG-..GSRP..EFVKLTMEYDDK.VSKSHHTCALM.PYMPP.ASDRLRNEQMIGQVLLMPKTASSLQKWARQQGSGG.-.-VKVTLNPDLYVTTYT.SGEACLTLDYK.....PLSVG..PYEAFTGpVAKAQ.DVGAVEAHVVCSVAADSLAAALSLCRIPAVSVPILRFYRSGIIAVVAGLLTSAGDLPLDLSVILFNHASEEAAASTASEPEDKsp......rvQPLGTGLQQRP.RHTVSPSPSp..pPPPRTPt.....wESPARP--------..---.................--------..ETPSP.AIPSHSSNTALErpl......avqlARKRTSSEARQKQKHPkkvKQAFNPLI...............................................................
#=GR EAD_EBVB9/4-404      SS    ..EEEEEE-TTTCGGGHHHHHHHH.HHHT.TSEEEEESGGGTT...TS-EEEEEEEESTTEEEEEEE-GGGEEEEEE-S-TTT......S-SEEEEES.B-SSSSSBHHHHHT-TTEEEEEEEEEE-SSS-..-SS-..-EEEEEEEETTS.S-EEEEEEE--.S----.GGGTCGGS-EEEEEE--HHHHHHHHHHHHHTTTSE.-.-EEEEEETTTTEEEEE.ETTEEEEEE-E.....E-SS-..GGGSS-S-BSSTS.-EEEESS-EEEEEEHHHHHHHHHHT-BTTTEEEEEEEETTSEEEEEEEEBTTS----EEEEEEE-----XXXXXXXXXXXXXXXX......XXXXXXXXXXXXX.XXXXXXXXXX..XXXXXXXX.....XXXXXXX--------..---.................--------..XXXXX.XXXXXXXXXXXXXXX......XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...............................................................
P88950_HHV8/6-396               ..HYGVRVDVTLLSKIRRVNEHIK.SATK.TGVVQVHGSACT......PTLSVLSSVGTAGVLGLRIK.NALTPL-VGHTEGS......GDVSFSFRN.TSVGSGFTHTRELFGANVLDAGIAFYRKGEACdtGAQP..QFVRTTISYGDN.LTSTVHKSVVDqKGILP.FHDRMEAGGRTTRLLLCGKTGAFLLKWLRQQKTKE.DqTVTVSVSETLSIVTFS.LGGVSKIIDFK.....P-ETK..PVSGWDGlKGKKSvDVGVVHTDALSRVSLESLIAALRLCKVPGWFTPGLIWHSNEILEVEGVP-TGCQSGDVKLSVLLL----EVNRSVSAEGGESS..........QKVPDSIPDSR.RQPELESPD....SPPLTP.......VGPFGPLEDASEDA..ASV.................--------..TSCPP.AAPTKDSTKRPH.............KRRSDSSQSRDRGKVP...KTTFNPLI...............................................................
Q9YTK8_ATHV3/10-320             ..TYGVGFKPSVLQENTKIYNHIR.AKVK.DGIIQIEGPTAS......PSLRVWSSIGD-GVLSFKID.NVVSEVFNCHMMPE......-NVSVSFRNiSPGGNTFLYTRELFGFNVKTATLMFSNR----..SGKP.fEFIKAKLEYCDK.VSTTRHTSTIT.AGILP.FANNVNSTNGLSRVVLTPKTAAMLQKWLRDHRTHR.-.TVSVGVNSTLAALILS.VGDSTKTVDLQ.....IV-DD..IAT---C.NNTNK.DWGFVQSDTWATVNITALSMALGLCKIPGVFVPGIKFCEGEVLEVRGMPVKLGSWTDTSLEVTLFS-THNTSEDTETDLLQET..........QNTSV------.---------....------.......--------------..---.................--------..-----.------------.............----------------...--------vsspadsa.......................................................
Q77NI0_9GAMA/6-394              ..HYGARVDVDALGSISRVYDHIK.GIVK.KGVIQISGQGRA......PVLSVLSSVGDAGVLGLRLK.NALAPLM-VYSDMT......DEVSFSFRN.TSLGNTFTHTREMFGVNIAEMNVAFYHHGDESdaEGKP..QFVRTTIAYGDN.HTSTVHKSVVDePNLPS.FHDRLEQAGTGNRLFLTVKTLTLLLKWLRQQKTRA.KqVVTVSLSETLAVATFT.VDGVSKIIDFK.....P--DT..PDAKWTCaRGRKL.DVGVVSSDLTTHVSLESLVAALNACKIPGFFLPGFRWHANEILEVEGLPLTDS-LADVRLGVMLLKVDPTDRNNAVPGN-LSE..........GADPEG-----.----VPELP....SPPRTPdldlkeqCVPIAE--DGAEPT..DGG.................--------..AKSLR.TSGSR-PEKKHG.............KRKHSSSPSRGKGKTKt.pRATFNPL-f..............................................................
U5NIG6_HHV8/6-400               ..HYGVRVDAEFLYGLRRVHDHLK.TSIK.SGVIQIHGPGTA......PVLSVLSSLGPAGVLGLRVK.NVLSPL-LGSCDAD......GEVNFSFRN.TSIGNGFTHTREIFGSNILETSIVFYRKGEAY..QGTPvpQFVRTTISYSDN.VTTTVHKSVLD.PNNLPaFYDRMEPGIKTNRLLLCGKTLTMLTRWLRQQKTRA.DqTVTVAASETLSVVTFS.VAGVSKILDFS.....P-ETS..ATADWETlKRKKQiDVGVVRTDAATQVSLESLLAALRLCKIPGWFTPGLVWHSNDILEVEGVS-IASHPCDVKLSVLLL----KVDEQSISEHRETH.........eKPPKDQPTPAL.DVSEEIRPP....SPISPP.......VTPGGEF----CAG..ISP.................KEG--KQPriDLHLP.SVAGKESR-RGQ.............KRRSAAGIGRERGKVS...KTTFNPLI...............................................................
E9M5P2_9GAMA/2-421              qr--TFEINTATLAAVAKVYNHVKgSACN.DGAIQVSGCADN......LNLTYVGAVGPGGVLRLDIL.DAVRQQYPCELETP......QPCLFSFLNrTCLGRDFSHAGQMFGPQLKSMTLSFYTREET-..----..QYVESKFVYD-E.TSKTVHTSAIS.NLHLP.AIRQLGSGQLVGTIFLTTKTTMAMIKWLKESVATI.QeNIKICLNEVLNIMVIS.TQKGSKTFEYAp...rNLVGEsvPPKKGKG.GTKMC.DYGEVMEDLETWVNGHSFIRALHICKIPGMCLPALKFHSSGILDVAGENISPASKFSLLVSVVKTDHSEDQPVPKPESEA---..........KPLTPGSS--E.EGPVP-RHS....-QQRTH.......ARPLSDLSSDE---..SSDeecsgvasatpacrgasSGSNQHQP..TPLSP.VAEEASQPQTPKrcllqqdvpsaplKRKPHRPAKLDI-KKP...RLKFNPLV...............................................................
P88996_MHV68/1-393              .m-QTFQLDTERLCQAAKLYQHTK.SDFGlNGMIQLSGSCNN......MSLSVLGSIGGCAILRLELL.EAARLHSSKDSSK-......-SAIYSFRNaSSLGREFTHGGELFGPKMESASLSFYGHHGV-..----..KYVEAQFV-HDS.SSKTVHTAAMQ.PITIP.PSCAFDDREANGIVTLSTKTAAALVKWLKQHTKTC.QsPVKVSISEILGVMVLS.VGDASMTVDVT.....PVNVS..SGKKTRG.GNKAS.DSGTISADATVHVNGHCLIRSLIVCKVPGCTTPRVKFHACGILEVDGAPVKQGELTQVKLSVALL----NVDS---STGRVLK..........EPVVTGASKDR.GASKSEDAD...gSPP-VP.......DHPKES---LTSDS..DSSvpgp.........rstdLSSLTHTP.sDRFSS.DLRSGCGGQQFL.............KRPPPKKDREPTTKRP...KLHFNH--f..............................................................
Q80BM1_SHV2/10-371              .s-YGVGFKPCVLQEHTKIYNHIK.AKVK.DGIIQIEGLTSS......PSLRIWSSIGE-GILSFKIN.NVVSEVFNCHMMPE......-NVSVSFRNiSPGGNTFLYTRELFGCNVKTATLMFSNR----..AGKP.fEFIKAKLEYCDK.VSATRHTSTIP.VGILP.FVENVNSTGVLSRVVLSPKTAAMLQKWLREHKAHK.-.TVSVMVNSTLAVLILT.VEDSTKTVDLH.....IV--D..DMS--LC.NNLSK.DWGVVQNDVQTKVNITALSAALGLCKIPGVFVPCIKFYESEVLEVCGMPVKLGSWVDTYLQVTLF---------CTPNLVEDT..........QAAGSD-----.---------....------.......YVPISP--SACLTA..DSA.................--DL--GA..TPEEP.TLSSNCQDSSVEnsp......alllKRKREK-DINKKSKKI...KLAFNPLI...............................................................
Q8UZI4_9GAMA/4-404              ..TQTLRFKTKALAVLSKCYDHAQ.THLK.GGVLQVNLLSVSyg..gcPRLAAVANAGTAGLISFEVSpDAVAEWQDHQGSEE......APAALSFRN.LAYGRTCVLGKELFGSAVQQASLQFYKRSQG-..GSRP..EFVKLTMDYDDNgCPRAHHTCALM.PYMPP.ATDRLRNEHLIGQVLLMPKTAASLQKWARRHGTGG.-.-VKVTLNPDLYVTTYT.SGEACLTLDYK.....PLSVG..PSEAFTGpVIKAQ.DTGAVEAHVTCSVAADSLAAALGLCRIPAVSVPILRFYRSGIIAVAAGLLASAGDLPLELSVILFNHDSEEADTSTPTEPEAKsp......apQPLGAELHQRP.RHTVSPSPS...pPPPRTPt.....wESPARP--------..---.................--------..ETPPP.AKPSH-SNAAPErpl......avqlARKRTSSEARQKQKHPkkvKQAFNPLI...............................................................
VG59_EHV2/8-414                 ..THCMALNVENFKACAKIHNHVK.NYLK.KGLVQIVGFETE......PVFQIMATACDGGILVFKVL.NPFESFNVSYSRME......-TLSLSFKN.QPHGNTYLYSKDLFGEAVKGASLTFLQRPGLC..--RP..DFVRSDVLMDDD.VTTSSHCTSLT.SWSPP.AHD-IRAGTVMSKVVLSIKTCTMLQKWLKDQKSKGePrCVRLCLNEILSVLVLS.VGEASKTVHLK.....PVEGN..PATSLLF.ADKQG.DVCIISDDEAHDVSLDSLLAALGVCRIPALCLPCFNFHSNGVLEVVGLQFKSSKPASGELSVFLLRANPQVDFNGVPEGDVQT..........QEVSSVASTCR.HLSESCSLD....-PPRTP.......ELPGSPDTFKEIPG..RSGsvhlerd...lscsdseEETPKQKP..AKAKP.AAAPKRSE----.............KRKREGGKKGPKAKSL...KLTFNPLI...............................................................
Q918P2_9GAMA/4-385              .c-AVFTLCPAALGKAAKMYEHVK.AHLK.LAMIQISDLHTA......PVLSIISNVGRAGILNFQLT.NAVISSD---ILTE......VTEPLAFRN.HSFGNTYLHSREFFGSNIEDIVVRFYKRDSAE..VPAP..EFVETRIAYNNG.VTETRHTSTVE.RHISP.VEKHLQKSFVEAKVILSIKTCTMLQKWLRQCKSAS.S.YARLHVNETLGVWVIT.VGDECKTIEFK.....SHSIE..PADAFLS.LDKPG.NFGAVLVDCTAVVSLECLIHAISICKVPSVCVPAFKFYSGGIVEVASAHLKQSKNPAAVVSAVLLNAEDLAEKDPEVLPSTSG..........HPPPSPIPQANlSDSEEDTVDf..sPPPPTP.......TSPLES--FILKPS..AKE.................PRPKSETP..HKRKQ.AEPSRY--KRPE.............KK--------------...--------akkisnif.......................................................
Q99CY3_BHV4/6-391               ..CYSANVKVPALTQNNKLYDHIK.NNLK.NGLIQLEGPSSG......PILSFLVNVGETGILVMKIK.DALEPMHEMDSPQEedlnktNNVSFSFRN.TSLGNTFVHSRELFGANVRDIYIVFYKR-ET-..SNVV..QFVRTTITYCDN.ETNTTHKSVVE.AQAMP.FIGKMETSEICSRVTLCPKTANALQKFLKQHKTKE.KrTVRVSINETLGVIIFT.IGEDSKTIDFK.....MSDQQ..DLEN-IQ.TAKVE.DVGHVNGDSVSYVSLESLTAALGCCKIPGCLTPCFRLYSSDILEVIGARLKGCTLGDASISVILLKAESTEENNSTSIGNLDSisknicenrgD---KYPQPCK.DEARSP---....------.......-------------S..TSV.................---EEERP..LTPSPpHCLSRPPNPTPV.............KRRHAD-LKKKNHKKL...RLSFTPL-i..............................................................
Q53CV4_9GAMA/6-394              ..HYGARVDVDALGNISKVYDHIK.GIVK.KGVIQISGQGRA......PVLSVLSSVGDAGVLGLRLK.NALAPLM-VYSDMT......DEVSFSFRN.TSLGNTFTHTREMFGVNITEMNVAFYHHGDESnaEGKP..QFVRTTIAYGDN.HTSTVHKSVVDePNLPS.FHDRLEQAGTGNRLFLTVKTLTLLSKWLRQQKTRA.KqVVTVSLSETLAVATFT.VDGVSKIIDFK.....P--DT..PDAKWTCaKGRKL.DVGVVSSDLTTHVSLESLVAALNACKIPGFFLPGFRWHANEILEVEGLPLTDS-LADVKLGVMLLKVDPTDRNNAVP------..........----GNLSEGA.DPEGVPELP....SPPRTP.......DLDLKE---QCVPN..AED.................GTEPTDGG..AKSLR.TSGSR-PEKKHG.............KRKHSSSPSRGKAKTKt.pRATFNPL-f..............................................................
K0FCA2_HHV8/6-386               ..HYGVRVDVTLLSKIRRVNEHIK.SATK.TGVVQVHGSACT......PTLSVLSSVGTAGVLGLRIK.NALTPL-VGHTEGS......GDVSFSFRN.TSVGSGFTHTRELFGANVLDAGIAFYRKGEACdtGAQP..QFVRTTISYGDN.LTSTVHKSVVDqKGILP.FHDRMEAGGRTTRLLLCGKTGAFLLKWLRQQKTKE.DqTVTVSVSETLSIVTFS.LGGVSKIIDFK.....P-ETK..PVSGWDGlKGKKSvDVGVVHTDALSRVSLESLIAALRLCKVPGWFTPGLIWHSNEILEVEGVP-TGCQSGDVKLSVLLL----EVNRSVSAEGGESS..........QKVPYRTPGGS.---------....------.......--------------..---.................--------..-----.------------.............----------------...--------rnwslrilplshqlvplgrwrtplrtlplspaapqrrqlrtaqrgltrgaqtraspgivgrcp
G3CKQ3_EBVG/4-404               ..TQTLRFKTKALAVLSKCYDHAQ.THLK.GGVLQVNLLSVNy...ggPRLAAVANAGTAGLISFEVSpDAVAEWQNHQSPEE......APAAVSFRN.LAYGRTCVLGKELFGSAVEQTSLQFYKRPQG-..GSRP..EFVKLTMEYDDK.VSKSHHTCALM.PYMPP.ASDRLRNEQMIGQVLLMPKTASSLQKWARQQGSGG.-.-VKVTLNPDLYVTTYT.SGEACLTLDYK.....PLSVG..PYEAFTGpVAKAQ.DVGAVEAHVVCSVAADSLAAALSLCRIPAVSVPILRFYRSGIIAVVAGLLTSAGDLPLDLSVILFNHASEEAAASTASEPEDKsp......rvQPLGTGLQQRP.RHTVSPSPSp..pPPPRTPt.....wESPARP--------..---.................--------..ETPSP.AIPSHSSNTALErpl......avqlARKRTSSEARQKQKHPkkvKQAFNPLI...............................................................
K9UR48_EBVG/4-404               ..TQTLRFKTKALAVLSKCYDHAQ.THLK.GGVLQVNLLSVNy...ggPRLAAVANAGTAGLISFEVSpDAVAEWQNHQSPEE......APAAVSFRN.LAYGRTCVLGKELFGSAVEQASLQFYKRPQG-..GSRP..EFVKLTMEYDDK.VSKSHHTCALM.PYMPP.ASDRLRNEQMIGQVLLMPKTASSLQKWARQQGSGG.-.-VKVTLNPDLYVTTYT.SGEACLTLDYK.....PLSVG..PYEAFTGpVAKAQ.DVGAVEAHVVCSVAADSLAAALSLCRIPAVSVPILRFYRSGIIAVVAGLLTSAGDLPLDLSVILFNHASEEAAASTASEPEDKsp......rvQPLGTGLQQRP.RHTVSPSPSp..pPPPRTPt.....wESPARP--------..---.................--------..ETPSP.AIPSHSSNTALErpl......avqlARKRTSSEARQKQKHPkkvKQAFNPLI...............................................................
Q2VSI2_9GAMA/4-385              .c-AVFTLCPAALGKAAKMYEHVK.AHLK.LAMIQISDLHTA......PVLSIISNVGRAGILNFQLT.NAVISSD---ILTE......VTEPLAFRN.HSFGNTYLHSREFFGSNIEDIVVRFYKRDSAE..VPAP..EFVETRIAYNNG.VTETRHTSTVE.RHISP.VEKHLQKSFVEAKVILSIKTCTMLQKWLRQCKSAS.S.YARLHVNETLGVWVIT.VGDECKTIEFK.....SHSIE..PADAFLS.LDKPG.NFGAVLVDCTAVVNLECLIHAISICKVPSVCVPAFKFYSGGIVEVASAHLKQSKNPAAVVSAVLLNAEDLAEKDPEVLPSTSG..........HPPPSPISQANlSDSEEDTVDf..sPPPPTP.......TSPLES--FILKPS..AKE.................PRPKSETP..HKRKQ.AEPSRY--KRPE.............KK--------------...--------akkisnif.......................................................
V5KUC5_EBVG/4-404               ..TQTLRFKTKALAVLSKCYDHAQ.THLK.GGVLQVNLLSVNy...ggPRLAAVANAGTAGLISFEVSpDAVAEWQNHQSPEE......APAAVSFRN.LAYGRTCVLGKELFGSAVEQASLQFYKRPQG-..GSRP..EFVKLTMEYDDK.VSKSHHTCALM.PYMPP.ASDRLRNEQMIGQVLLMPKTASSLQKWARQQGSGG.-.-VKVTLNPDLYVTTYT.SGEACLTLDYK.....PLSVG..PYEAFTGpVAKAQ.DVGAVEAHVVCSVAADSLAAALSLCRIPAVSVPILRFYRSGIIAVVAGLLTSAGDLPLDLSVILFNHASEEAATSTASEPEDKsp......rvQPLGTGLQQRP.RHTVSPSPSp..pPPPRTPt.....wESPARP--------..---.................--------..ETPSP.AIPSHSSNTALErpl......avqlARKRTSSEARQKQKHPkkvKQAFNPLI...............................................................
#=GC SS_cons                    ..EEEEEE-CCCCHHHHHHHHHHH.HHHT.TSEEEEECCCCTT...TSEEEEEEEEETTTEEEEEEESGCGEEEEECTSTTTT......SECEEEEES.B-TTSSSBHHHHHT-TTEEEEEEEEEE-SSS-..-SS-..-EEEEEEEETTT.T-EEEEEEE--.TTS--.GCCTCGCSTCEEEEE--HHHHHHHHHHHHCTTTSC.-.EEEEEEETTTTEEEEE.ETTEEEEEE-E.....E-SSS..GGCTTBTTBSTTSS-EEEESS-EEEEEEHHHHHHHHHHT-BTTTEEEEEEEETTSEEEEEEEEBTTSTTTTEEEEEEE-----XXXXXXXXXXXXXXXX......XXXXXXXXXXXXX.XXXXXXXXXX..XXXXXXXX.....XXXXXXX--------..---.................--------..XXXXX.XXXXXXXXXXXXXXX......XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX...............................................................
#=GC seq_cons                   ..phshclcsssLupluKlY-HlK.oplK.sGllQlsG.uss......PsLulluslGsAGlLuhclp.sAls.h.stpo.t-......sssuhSFRN.puhGsTFlaoRELFGssVcpAsltFY+Rsps...uupP..pFV+sTlsYsDs.lopTpHTSslp.shh.P.hpD+lcssthhu+VlLssKTushLQKWLRQp+ops...sV+VolNEsLuVhsaT.lG-soKTlDaK.....Phsss..Pscsaps.hsKsp.DsGsVpsDssspVul-SLhAALulCKIPGshlPsl+FauusILEVsGs.lpsup.sslcLSVlLhpht.ptspssssptspsp..........Qshssshtpt..pts...p.s....sPPhTP.......psPhps.......s...t............................ppspP.shsS+.sspp.t.............KR+pssstt+p+tKp....K.sFNPLl...............................................................
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