GenomeNet

Database: Pfam
Entry: Herpes_LP
LinkDB: Herpes_LP
Original site: Herpes_LP 
#=GF ID   Herpes_LP
#=GF AC   PF03363.8
#=GF DE   Herpesvirus leader protein
#=GF AU   Mifsud W
#=GF SE   Pfam-B_1664 (release 6.6)
#=GF GA   25.00 25.00;
#=GF TC   29.70 29.60;
#=GF NC   21.40 20.80;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   10590127
#=GF RT   Sequence and functional analysis of EBNA-LP and EBNA2 proteins
#=GF RT   from nonhuman primate lymphocryptoviruses. 
#=GF RA   Peng R, Gordadze AV, Fuentes Panana EM, Wang F, Zong J, Hayward
#=GF RA   GS, Tan J, Ling PD; 
#=GF RL   J Virol 2000;74:379-389.
#=GF RN   [2]
#=GF RM   11024123
#=GF RT   Conserved regions in the Epstein-Barr virus leader protein
#=GF RT   define distinct domains required for nuclear localization and
#=GF RT   transcriptional cooperation with EBNA2. 
#=GF RA   Peng R, Tan J, Ling PD; 
#=GF RL   J Virol 2000;74:9953-9963.
#=GF DR   INTERPRO; IPR005030;
#=GF SQ   54
#=GS Q91QU6_EBVG/1-66      AC Q91QU6.1
#=GS Q8UZJ5_9GAMA/1-131    AC Q8UZJ5.1
#=GS EBNA5_EBVA8/1-134     AC Q1HVI8.1
#=GS EBNA5_EBVB9/133-268   AC Q8AZK7.1
#=GS Q69141_EBVG/1-109     AC Q69141.1
#=GS Q91QU5_EBVG/1-44      AC Q91QU5.1
#=GS Q8UZJ5_9GAMA/196-371  AC Q8UZJ5.1
#=GS Q56R59_EBVG/1-44      AC Q56R59.1
#=GS EBNA5_EBVG/199-334    AC P0C732.1
#=GS EBNA5_EBVG/331-505    AC P0C732.1
#=GS Q69125_EBVG/265-381   AC Q69125.1
#=GS Q9Q5K1_9GAMA/129-302  AC Q9Q5K1.1
#=GS EBNA5_EBVA8/67-202    AC Q1HVI8.1
#=GS Q8UZJ5_9GAMA/66-198   AC Q8UZJ5.1
#=GS Q9Q5K3_9GAMA/1-65     AC Q9Q5K3.1
#=GS Q91QS0_9GAMA/1-46     AC Q91QS0.1
#=GS Q9Q5L0_CHV12/1-166    AC Q9Q5L0.1
#=GS Q91QU4_EBVG/1-66      AC Q91QU4.1
#=GS EBNA5_EBVG/265-381    AC P0C732.1
#=GS Q91QS1_9GAMA/1-68     AC Q91QS1.1
#=GS Q91QZ5_CHV12/1-65     AC Q91QZ5.1
#=GS EBNA5_EBVB9/67-202    AC Q8AZK7.1
#=GS Q69125_EBVG/1-135     AC Q69125.1
#=GS Q9Q5K2_9GAMA/1-45     AC Q9Q5K2.1
#=GS EBNA5_EBVG/133-268    AC P0C732.1
#=GS EBNA5_EBVA8/265-394   AC Q1HVI8.1
#=GS Q9Q5K1_9GAMA/1-130    AC Q9Q5K1.1
#=GS Q56TK3_EBVG/1-44      AC Q56TK3.1
#=GS Q69136_EBVG/1-136     AC Q69136.1
#=GS Q69125_EBVG/67-202    AC Q69125.1
#=GS Q8UZJ5_9GAMA/131-260  AC Q8UZJ5.1
#=GS Q69147_EBVG/1-90      AC Q69147.1
#=GS EBNA5_EBVB9/199-334   AC Q8AZK7.1
#=GS Q69148_EBVG/1-24      AC Q69148.1
#=GS Q5JC37_EBVG/1-44      AC Q5JC37.1
#=GS EBNA5_EBVG/1-135      AC P0C732.1
#=GS Q69147_EBVG/86-260    AC Q69147.1
#=GS EBNA5_EBVG/67-202     AC P0C732.1
#=GS Q69125_EBVG/331-505   AC Q69125.1
#=GS EBNA5_EBVB9/1-135     AC Q8AZK7.1
#=GS Q91QS2_9GAMA/1-44     AC Q91QS2.1
#=GS Q69136_EBVG/133-307   AC Q69136.1
#=GS Q69125_EBVG/199-334   AC Q69125.1
#=GS Q56R60_EBVG/1-44      AC Q56R60.1
#=GS Q91QS3_9GAMA/1-70     AC Q91QS3.1
#=GS Q91QU3_EBVG/1-44      AC Q91QU3.1
#=GS Q56TK2_EBVG/1-44      AC Q56TK2.1
#=GS Q91QZ4_9GAMA/1-66     AC Q91QZ4.1
#=GS Q69125_EBVG/133-268   AC Q69125.1
#=GS EBNA5_EBVA8/133-268   AC Q1HVI8.1
#=GS EBNA5_EBVA8/331-505   AC Q1HVI8.1
#=GS EBNA5_EBVA8/199-334   AC Q1HVI8.1
#=GS EBNA5_EBVB9/331-505   AC Q8AZK7.1
#=GS EBNA5_EBVB9/265-381   AC Q8AZK7.1
Q91QU6_EBVG/1-66                 .....------------------------------------------.-----------------------PRGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSG----------------------------..----.------------...
Q8UZJ5_9GAMA/1-131               .....MGDPSEATGPSRPGPPGLGPEGPFGDLLRRRRHNSPTGGDPQgPTRVRRRVFLEEEDGPVSGPPV--RGDPSEATGPSRPGPPGLGPEGPFGDLLRRRRHNSPTGGDPQ..gPTRVRRRVFLEEED.GPVSGPPV-----------------------------..----.------------r..
EBNA5_EBVA8/1-134                .....MGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRG-------------------------..----.------------...
EBNA5_EBVB9/133-268              .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDR-----------------------..----.------------...
Q69141_EBVG/1-109                .....------------------------------------------.------------------------RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPLRPRPRPPARSLREWLLRIRDHFEPPT..VTTQ.RQSVYIEEEED-e..
Q91QU5_EBVG/1-44                 .....------------------------------------------.------------------------------------------------------------------...--------------.---------PLRPRPRPPARSLREWLLRIRDRFEPPP..VTTQ.RQSVYIEEEED-e..
Q8UZJ5_9GAMA/196-371             .....RGDPSEATGPSRPGPPGLGPEGPFGDLLRRRRHNSPTGGDPQgPTRVRRRVFLEEEDGPVSGPPV--RGDPSEATGPSRPGPPGLGPEGPFGDLLRRRRHNSPTGGDPQ..gPTRVRRRVFLEEED.GPVSGPPVRPQGPLIQPGARSWSEWLARSRQRTNPQQ..VTTTcRRRVYIEEEEEI...
Q56R59_EBVG/1-44                 .....---------------------GPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEGEVVSGSPS--------------------------------------------...--------------.-------------------------------------..----.------------g..
EBNA5_EBVG/199-334               .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDR-----------------------..----.------------...
EBNA5_EBVG/331-505               .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPLRPRPRPPARSLREWLLRIRDHFEPPT..VTTQ.RQSVYIEEEED-e..
Q69125_EBVG/265-381              .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSLSPTRGGQE...PRRVRRRVL-----.-------------------------------------..----.------------...
Q9Q5K1_9GAMA/129-302             ....v-GDPSEATGPSRPGPPGLGPEGPFGDLLRRRRHNSPTGGDPQgPTRVRRRVFLEEEERPVSGPPV---GDPSEATGPSRPGPPGLGPEGPFGDLLRRRRHNSPTGGDPQ..gPTRVRRRVFLEEEE.RPVSGPPV-PQGPLIQPGARSWSEWLARSRQRTNPQQ..VTTTcRRRVYIEEEEEI...
EBNA5_EBVA8/67-202               .....RGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDR-----------------------..----.------------...
Q8UZJ5_9GAMA/66-198              .....RGDPSEATGPSRPGPPGLGPEGPFGDLLRRRRHNSPTGGDPQgPTRVRRRVFLEEEDGPVSGPPV--RGDPSEATGPSRPGPPGLGPEGPFGDLLRRRRHNSPTGGDPQ..gPTRVRRRVFLEEED.GPVSGPPVR----------------------------..----.------------gd.
Q9Q5K3_9GAMA/1-65                .....-GDPSEATGPSRPGPPGLGPEGPFGDLLRRRRHNSPTGGDPQgPTRVRRRVFLEEEERPVSGPPV--------------------------------------------...--------------.-------------------------------------..----.------------r..
Q91QS0_9GAMA/1-46                .....------------------------------------------.------------------------------------------------------------------...--------------.---------PPRPGIQPPAKSLREWLVRMSSRYNPPPppPITV.RRTVYIEEEEE-n..
Q9Q5L0_CHV12/1-166               .....MGDPSQAPGPSLPGPSGLGPEGPFGQLLRRRRPSSPPGGDPEgPKHIRRRVCLEEE--AVSGPPTRPRGDPSQAPGPSLPGPSGLGPEGPFGQLLRRRRPSSPPGGDPE..gPKHIRRRVCLEEE-.--------APQRPLIQPAARSWREWLARPGPRPETQP..VTTF.RRRIYIEEEEE-s..
Q91QU4_EBVG/1-66                 .....------------------------------------------.-----------------------PRGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSG----------------------------..----.------------...
EBNA5_EBVG/265-381               .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVL-----.-------------------------------------..----.------------...
Q91QS1_9GAMA/1-68                ....s------------------------------------------.------------------------RGDPSEAAGPSRSGPSGLGPQGPLTDLLSRRRSSSPPRGDPQ..aPKRVRRRVLLRQEE.EEVVRGPS-----------------------------..----.------------se.
Q91QZ5_CHV12/1-65                .....------------------------------------------.-----------------------PRGDPSQAPGPSLPGPSGLGPEGPFGQLLRRRRPSSPPGGDPQ..gPKQIRRRVCLEEE-.-AVSGPPT-----------------------------..----.------------r..
EBNA5_EBVB9/67-202               .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDR-----------------------..----.------------...
Q69125_EBVG/1-135                .....MGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGD------------------------..----.------------...
Q9Q5K2_9GAMA/1-45                .....------------------------------------------.------------------------------------------------------------------...--------------.---------PQGPLIQPGARSWSEWLARSRQRTNPQQ..VTTTcRRRVYIEEEEEI...
EBNA5_EBVG/133-268               .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDR-----------------------..----.------------...
EBNA5_EBVA8/265-394              .....RGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPS-----------------------------..----.------------...
Q9Q5K1_9GAMA/1-130               .....MGDPSEATGPSRPGPPGLGPEGPFGDLLRRRRHNSPTGGDPQgPTRVRRRVFLEEEERPVSGPPV---GDPSEATGPSRPGPPGLGPEGPFGDLLRRRRHNSPTGGDPQ..gPTRVRRRVFLEEEE.RPVSGPPVG----------------------------..----.------------...
Q56TK3_EBVG/1-44                 .....---------------------GPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPS--------------------------------------------...--------------.-------------------------------------..----.------------g..
Q69136_EBVG/1-136                .....MGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDR-----------------------..----.------------...
Q69125_EBVG/67-202               .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDR-----------------------..----.------------...
Q8UZJ5_9GAMA/131-260             .....RGDPSEATGPSRPGPPGLGPEGPFGDLLRRRRHNSPTGGDPQgPTRVRRRVFLEEEDGPVSGPPV--RGDPSEATGPSRPGPPGLGPEGPFGDLLRRRRHNSPTGGDPQ..gPTRVRRRVFLEEED.GPVSGPPV-----------------------------..----.------------...
Q69147_EBVG/1-90                 .....------------------------------------------.-----RRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDRS----------------------..----.------------...
EBNA5_EBVB9/199-334              .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDR-----------------------..----.------------...
Q69148_EBVG/1-24                 .....------------------------------------------.------------------------RGDRSEGPGPTRPGPPGIGPE---------------------...--------------.-------------------------------------..----.------------vsg
Q5JC37_EBVG/1-44                 .....---------------------GPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPS--------------------------------------------...--------------.-------------------------------------..----.------------g..
EBNA5_EBVG/1-135                 .....MGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGD------------------------..----.------------...
Q69147_EBVG/86-260               .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPLRPRPRPPARSLREWLLRIRDHFEPPT..VTTQ.RQSVYIEEEED-e..
EBNA5_EBVG/67-202                .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDR-----------------------..----.------------...
Q69125_EBVG/331-505              .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSLSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPLRPRPRPPARSLREWLLRIRDHFEPPT..VTTQ.RQSVYIEEEED-e..
EBNA5_EBVB9/1-135                .....MGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGD------------------------..----.------------...
Q91QS2_9GAMA/1-44                pqgil------------------------------------------.------------------------------------------------------------------...--------------.---------------VPPAQSFRQWLARIPDRTGQET..VTSIrRQTIYIEEEEE-e..
Q69136_EBVG/133-307              .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPLRPRPRPPARSLREWLLRIRDHFEPPT..VTTQ.RQSVYIEEEED-e..
Q69125_EBVG/199-334              .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDR-----------------------..----.------------...
Q56R60_EBVG/1-44                 .....---------------------GPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPS--------------------------------------------...--------------.-------------------------------------..----.------------g..
Q91QS3_9GAMA/1-70                .....------------------------------------------.-----------------------PRGDSSEAPGPARHGPPGLGPEGLFGQLLSSRRPSSPSQGGQQepePKRVRRRVLLKQEEeEVVSRS-------------------------------..----.------------qrg
Q91QU3_EBVG/1-44                 .....------------------------------------------.------------------------------------------------------------------...--------------.---------PLRPRPQPPAQSLREWLLRISERFDPHP..VATR.RQSVYIEEEED-e..
Q56TK2_EBVG/1-44                 .....---------------------GPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPS--------------------------------------------...--------------.-------------------------------------..----.------------g..
Q91QZ4_9GAMA/1-66                .....------------------------------------------.-----------------------PRGDPSEAPGPSRPRPPGLGPEGPFGELLRRRRHSSPTGGGQE..gSRRVRRRVLVEEE-.QSVSGDPV-----------------------------..----.------------r..
Q69125_EBVG/133-268              .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDR-----------------------..----.------------...
EBNA5_EBVA8/133-268              .....RGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDR-----------------------..----.------------...
EBNA5_EBVA8/331-505              .....RGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPLRPRPQPPAQSLREWLLRISERFDPHP..VATR.RQSVYIEEEED-e..
EBNA5_EBVA8/199-334              .....RGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEVPGPARPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPRGDR-----------------------..----.------------...
EBNA5_EBVB9/331-505              .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVLVQQEE.EVVSGSPSGPLRPRPRPPARSLREWLLRIRDHFEPPT..VTTQ.RQSVYIEEEED-e..
EBNA5_EBVB9/265-381              .....RGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE.PRRVRRRVLVQQEEEVVSGSPSGPRGDRSEGPGPTRPGPPGIGPEGPLGQLLRRHRSPSPTRGGQE...PRRVRRRVL-----.-------------------------------------..----.------------...
#=GC seq_cons                    .....hGD.SEssGPsRPGPPGlGPEGPhGQLLRR+RssSPTtGs.E.P+RVRRRVLVQQEEEVVSGSPS.PRGDpSEuPGPoRPGPPGlGPEGPhGQLLRR+RssSPTpGGQE...P+RVRRRVLlppE-.psVSGsPs...................................................
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