GenomeNet

Database: Pfam
Entry: Herpes_UL14
LinkDB: Herpes_UL14
Original site: Herpes_UL14 
#=GF ID   Herpes_UL14
#=GF AC   PF03580.12
#=GF DE   Herpesvirus UL14-like protein
#=GF AU   Bateman A
#=GF SE   Pfam-B_2982 (release 7.0)
#=GF GA   25.00 25.00;
#=GF TC   206.00 205.80;
#=GF NC   22.60 21.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   11161269
#=GF RT   The UL14 protein of herpes simplex virus type 2 translocates the
#=GF RT   minor capsid protein VP26 and the DNA cleavage and packaging
#=GF RT   UL33 protein into the nucleus of coexpressing cells. 
#=GF RA   Yamauchi Y, Wada K, Goshima F, Takakuwa H, Daikoku T, Yamada M,
#=GF RA   Nishiyama Y; 
#=GF RL   J Gen Virol 2001;82:321-330.
#=GF RN   [2]
#=GF RM   10590088
#=GF RT   Herpes simplex virus type 1 gene UL14: phenotype of a null
#=GF RT   mutant and identification of the encoded protein. 
#=GF RA   Cunningham C, Davison AJ, MacLean AR, Taus NS, Baines JD; 
#=GF RL   J Virol 2000;74:33-41.
#=GF DR   INTERPRO; IPR005207;
#=GF CC   This is a family of Herpesvirus proteins including UL14. UL14
#=GF CC   protein is a minor component of the virion tegument [2] and is
#=GF CC   expressed late in infection. UL14 protein can influence the
#=GF CC   intracellular localisation patterns of a number of proteins
#=GF CC   belonging to the capsid or the DNA encapsidation machinery [1].
#=GF SQ   5
#=GS TEG3_PSHV1/11-160  AC Q6UDH8.1
#=GS TEG3_HHV11/7-155   AC P04291.2
#=GS TEG3_VZVD/11-155   AC P09295.1
#=GS TEG3_GAHVM/8-155   AC Q9E6Q3.1
#=GS TEG3_HHV2H/7-155   AC P89437.1
TEG3_PSHV1/11-160             ...TRRERRIQARTkimeYIKGSAYKASVLEMTSAGVSPSHPAFRHAFTKATEHEEAAKIAAQVDKRMVSVRRKIARITAVVNGQRELASELKGYRRYLSSGFLDTFAAEADKLYEDEISLECAEAEL...SQHLPAGEDYDEGENELLVRWQLE-g
TEG3_HHV11/7-155              haa--LRRR-LAET....HLRAEIYKDQTLQLHREGVSTQDPRFVGAFMAAKAAHLELEARLKSRARLEMMRQRATCVKIRVEEQAARRDFLTAHRRYLDPALGERLDAVDDRLADQEEQLEEAATNAslwGDGDLAEGWMSPADSDLLVMWQLTS.
TEG3_VZVD/11-155              ...HRRNRVKLVEA....HNRAGLFKERTLDLIRGGASVQDPAFVYAFTAAKEACADLNNQLRSAARIASVEQKIRDIQSKVEEQTSIQQILNTNRRYIAPDFIRGLDKTEDDNTDNIDRLEDAVGP-...NIEHENHTWFGEDDEALLTQWMLTT.
TEG3_GAHVM/8-155              ...RRRRRRILAEC....RTREAVYKERTLELLSQGVETDDPEFIEVFTSARNAHSDYKAQLRSNMRLEATDRKTKIIQRHIDEQLDRRLILDINRKLLNPKLQLQLDQTEEAILEKEDILAQTIDDIt.lNDSITNTDELDEESEALLTKWILNQ.
TEG3_HHV2H/7-155              haa--LRRR-LAET....HLRAEVYRDQTLQLHREGVSTQDPRFVGAFMAAKAAHLELEARLKSRARLEMMRQRATCVKIRVEEQAARRDFLTAHRRYLDPALSERLDAADDRLADQEEQLEEAAANAslwGDGDLADGWMSPGDSDLLVMWQLTS.
#=GC seq_cons                 ...pRRRRRhLAET....HlRAulYK-pTL-LpRpGVSTQDPcFVtAFTAAKsAHt-LcApL+ScARLEusRQKsssIpt+VEEQsuRRshLsuaRRYLsPuLt-pLDAs-D+LsDpE-pLE-Asusho.huDuchAcsWhuEuDs-LLVpWQLTo.
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