GenomeNet

Database: Pfam
Entry: Herpes_UL92
LinkDB: Herpes_UL92
Original site: Herpes_UL92 
#=GF ID   Herpes_UL92
#=GF AC   PF03048.12
#=GF DE   UL92 family
#=GF PI   2111; UL92; 
#=GF AU   Mifsud W
#=GF SE   Pfam-B_2111 (release 6.4)
#=GF GA   20.50 20.50;
#=GF TC   20.70 20.70;
#=GF NC   20.40 20.40;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF DR   INTERPRO; IPR004289;
#=GF CC   Members of this family, found in several herpesviruses, include
#=GF CC   EBV BDLF4 Swiss:P03223, HCMV UL92 Swiss:P16798, HHV8 31
#=GF CC   Swiss:P88920,  HSV6 U63 Swiss:P24440. Their function is unknown.
#=GF CC   The N terminus of this protein contains 6 conserved cysteines
#=GF CC   and histidines that might form a zinc binding domain (A Bateman
#=GF CC   pers. obs.).
#=GF SQ   41
#=GS A9SKW4_PHYPA/149-234      AC A9SKW4.1
#=GS UL92_HHV6Z/30-215         AC Q9QJ21.1
#=GS A0A067G1M8_CITSI/208-309  AC A0A067G1M8.1
#=GS W1NHU2_AMBTC/239-331      AC W1NHU2.1
#=GS M1BKZ0_SOLTU/257-341      AC M1BKZ0.1
#=GS V7CMD0_PHAVU/216-315      AC V7CMD0.1
#=GS UL92_HHV6U/28-213         AC P24440.1
#=GS I1J879_SOYBN/216-297      AC I1J879.1
#=GS R0GAS0_9BRAS/210-318      AC R0GAS0.1
#=GS A0A0J8CJL9_BETVU/224-324  AC A0A0J8CJL9.1
#=GS L1JLC2_GUITH/2-114        AC L1JLC2.1
#=GS A0A0D2RK00_GOSRA/215-317  AC A0A0D2RK00.1
#=GS W9SGX0_9ROSA/206-301      AC W9SGX0.1
#=GS UL92_ALHV1/22-213         AC O36380.1
#=GS A0A0D2T4U1_GOSRA/92-194   AC A0A0D2T4U1.1
#=GS M5XEM2_PRUPE/214-295      AC M5XEM2.1
#=GS M1BKY9_SOLTU/279-363      AC M1BKY9.1
#=GS M0RYS6_MUSAM/397-500      AC M0RYS6.1
#=GS V4STV2_9ROSI/224-325      AC V4STV2.1
#=GS A0A061G875_THECC/221-314  AC A0A061G875.1
#=GS U5GL78_POPTR/222-303      AC U5GL78.1
#=GS G7K412_MEDTR/218-300      AC G7K412.1
#=GS Y030_OSHVF/25-163         AC Q6R7J3.1
#=GS UL92_EHV2/81-274          AC Q66634.1
#=GS UL92_EBVA8/25-220         AC P0CK57.1
#=GS I1LIG1_SOYBN/216-317      AC I1LIG1.1
#=GS UL92_HCMVM/8-194          AC F5HAS7.1
#=GS S8C2M3_9LAMI/81-177       AC S8C2M3.1
#=GS A0A067KI94_JATCU/210-286  AC A0A067KI94.1
#=GS M1BKZ1_SOLTU/45-132       AC M1BKZ1.1
#=GS L1I894_GUITH/161-258      AC L1I894.1
#=GS UL92_SHV21/6-195          AC Q01011.1
#=GS X6P7N8_RETFI/39-171       AC X6P7N8.1
#=GS A0A0B0PFQ7_GOSAR/216-318  AC A0A0B0PFQ7.1
#=GS A0A059C2U5_EUCGR/351-456  AC A0A059C2U5.1
#=GS A0A0D2TAM3_GOSRA/164-266  AC A0A0D2TAM3.1
#=GS UL92_EBVB9/25-220         AC P0CK56.1
#=GS L1IIQ9_GUITH/59-165       AC L1IIQ9.1
#=GS D7TFB9_VITVI/198-280      AC D7TFB9.1
#=GS UL92_HHV8P/1-188          AC Q2HRA1.1
#=GS L1I6P4_GUITH/89-198       AC L1I6P4.1
A9SKW4_PHYPA/149-234                 .............csgrs----------CS.YHQIGDVFLCEKTGRAHVCDDT.CKETLL.DpSN.EL.LVCTVSGRCF.DRWLSpseenyAEEFVRQQQ...A-------.....--------.-..------------------------------.-------------------------....--------------------------------------------------danagadegepflg....................................................................
UL92_HHV6Z/30-215                    ..................SQMYNLHNPITF.ELGLGNVFVCMRCLTVHHCDMQ.TDCTIV.N.TH.EG.YVCAKTGLFY.SGWMPt....yADCFLEPIC...EPNIETV-.....------NV.V..VVLLSYVYSFLMENKERYAAIIDSIIKDGK.FIKNVEDAVFYTFN---AVFTNSTFn.kiPLTTISRLFVQLIIGGHAKGTIYDSNVIRVSRRKREDSLLKKMRLEYGN-a.................................................................................
A0A067G1M8_CITSI/208-309             .............hacsg--------DLCT.YHQVGNLFVCEKTGYVHVCDDT.CREMAM.D.AK.DGiMVCKISGRCF.EMLMS......-PDELEPDP...EQQSSVI-.....DE------.-..------------------------------.-------------------------....--------------------------------------------------epfmgsgrfaraymlgyschdekelea.......................................................
W1NHU2_AMBTC/239-331                 ............htcsgn---------TCS.YSQIGDVYLCEKTGRVHVCDDT.CRETLV.D.SF.GGfLVCAISGHCS.ERWFS......SEEEIDN--...--------.....--------.-..------------------------------.-------------------------....--------------------------------------------------dqqlcgvtdeaepfmgsgrfarayllgy......................................................
M1BKZ0_SOLTU/257-341                 ............hacsge---------TCA.YHQIGDVFVCEKTGNVHVCDDT.CREVVL.DpTN.GL.LVCTISGHCF.DSMLL......SPDEMEPDV...DQQQAG--.....--------.-..------------------------------.-------------------------....--------------------------------------------------ttdeaeplmgsg......................................................................
V7CMD0_PHAVU/216-315                 ............htctge---------TCS.YYQIGDVFICEKTGQVHVCDDTcREVIMD.P.TN.EL.LVCTISGHCF.DRLLS......-PSEMEPDT...EQ------.....--------.-..------------------------------.-------------------------....--------------------------------------------------lqgaatdeaepfmgsgrfarayllgyncadek..................................................
UL92_HHV6U/28-213                    ..................SQMYNLHNPITF.ELGLGNVFVCMRCLTVHHCDMQ.TDCTIV.N.TH.EG.YVCAKTGLFY.SGWMPa....yADCFLEPIC...EPNIETV-.....------NV.V..VVLLSYVYSFLMENKERYAAIIDSIIKDGK.FIKNVEDAVFYTFN---AVFTNSTFn.kiPLTTISRLFVQLIIGGHAKGTIYDSNVIRVSRRKREDSLLKKMRLEYGN-a.................................................................................
I1J879_SOYBN/216-297                 ............hacsge---------TCS.YYHIGDVFICEKTGQVHVCDDTcREVVMD.P.TN.EL.LVCTISGHCF.-DRLL......SPSEMEPDT...EQQQGGVT.....--------.-..------------------------------.-------------------------....--------------------------------------------------deaepfmg..........................................................................
R0GAS0_9BRAS/210-318                 .............clgtk----------CS.YHQIDDVFICKETGNVHVCDDNcKEVILS.P.EG.DL.MVCTISGLCS.ETLLVqt.dpdADGFYEEEA...ELELEVFT.....DKSRLGTY.L..S-----------------------------.-------------------------....--------------------------------------------------lslaslsiysfyiqhiseqfa.............................................................
A0A0J8CJL9_BETVU/224-324             .............htcsg--------EVCS.YFQIGNVFICEKTGNVHVCDDT.CKEVVPdP.AN.EL.LVCTISGHCF.DRLLS......-PSEMD---...--------.....--------.-..------------------------------.-------------------------....--------------------------------------------------gdteqelqqgvatdeaepfmgagrfarayllgyncdde............................................
L1JLC2_GUITH/2-114                   ...............dla------------.--------GCLECGEVHNCKDE.SSCDLI.D.EN.DS.RVCFITGCCV.KQKVF.....pMDEFMDNMMldeDILVSNVS.....NRDFYNKV.MsqKTVEDSLYSFD-------------------.-------------------------....--------------------------------------------------evnkclvwilssdvckksymneknrmm.......................................................
A0A0D2RK00_GOSRA/215-317             ............hacsge---------TCT.YYQIGDVFVCEKTGQVHVCDDTcREVILD.P.NN.EL.LVCTISGHCF.DRLLS......PSE------...--------.....--------.-..------------------------------.-------------------------....--------------------------------------------------meldaeqqqaggtdeaepflgsgrfarayllgyncedekele........................................
W9SGX0_9ROSA/206-301                 ..........mdhacsge---------TCS.YYQIGDVFVCEKTGHVHVCDDTcREAVMD.P.TN.EV.LVCTISGHCF.DGLLS......-PAEMEPDV...EQ------.....--------.-..------------------------------.-------------------------....--------------------------------------------------qqgggtdeaepfmgsgrfarayllgy........................................................
UL92_ALHV1/22-213                    ..................CYFTKMITMATT.FHTVDNIFVCTECKTYHVCDGG.EDCYLV.N.MG.EG.LVCELTGRCA.VNSVSfgnprpMSPVIYPHH...NTPGPNQF.....----LDSV.V..QCVQRDVAIYL--SSSSYEEVKDKVLLCQGeLREEVADLIKTTFNHCQNIFQSAQC....AYSLICSIYIHVIISVYSSKTVYGNLIFKCTKNKKFDSVAKSIRQAWMSI..................................................................................
A0A0D2T4U1_GOSRA/92-194              ............hacsge---------TCT.YYQIGDVFVCEKTGQVHVCDDTcREVILD.P.NN.EL.LVCTISGHCF.DRLLS......PSE------...--------.....--------.-..------------------------------.-------------------------....--------------------------------------------------meldaeqqqaggtdeaepflgsgrfarayllgyncedekele........................................
M5XEM2_PRUPE/214-295                 .............hacsg--------EICT.YYQIGDVFVCEKTGQVHVCDDNcREVVMD.P.TN.EL.WVCTISGHCF.-DRLL......SPAEMEPDS...ELQQGG--.....--------.-..------------------------------.-------------------------....--------------------------------------------------vtdeaepfmg........................................................................
M1BKY9_SOLTU/279-363                 ............hacsge---------TCA.YHQIGDVFVCEKTGNVHVCDDT.CREVVL.DpTN.GL.LVCTISGHCF.DSMLL......SPDEMEPDV...DQQQAG--.....--------.-..------------------------------.-------------------------....--------------------------------------------------ttdeaeplmgsg......................................................................
M0RYS6_MUSAM/397-500                 .............icsgn---------TCS.YSHIGDVFICERTGRVHVCDDA.CREVVV.D.RQsGG.FVCTISGHCF.DRLLS.....pEEELVTSEN...EQQQDGAV.....D-------.-..------------------------------.-------------------------....--------------------------------------------------eaepfmgsgrfarayllgyncddekele......................................................
V4STV2_9ROSI/224-325                 .............hacsg--------DLCT.YHQVGNLFVCEKTGYVHVCDDT.CREMAM.D.AK.DGiMVCKISGRCF.EMLMS......-PDELEPDP...EQQSSVI-.....DE------.-..------------------------------.-------------------------....--------------------------------------------------epfmgsgrfaraymlgyschdekelea.......................................................
A0A061G875_THECC/221-314             ............hacsge---------TCS.YYQIGDVFVCEKTGQVHVCDDTcREVILD.P.TN.EL.LVCTISGHCF.DRLLS......P--------...--------.....--------.-..------------------------------.-------------------------....--------------------------------------------------semeldpeqqqgggtdeaepfmgsgrfarayllgy...............................................
U5GL78_POPTR/222-303                 ............hacsge---------TCS.YFKLGDVFVCEKTGNVHVCDDTcREVIMD.P.TN.EL.LVCTISGHCF.DRWLL......---------...--------.....--------.-..------------------------------.-------------------------....--------------------------------------------------psemepdpdqqqggltdeaepfmg..........................................................
G7K412_MEDTR/218-300                 .............hacsg--------KTCS.YYQIGDVFICEKTGQVHVCDET.CKEVVM.D.PEdEL.LVCTISGHCF.DRLLS......-PSEM----...--------.....--------.-..------------------------------.-------------------------....--------------------------------------------------epdsqqgvaadeeepfmgsgr.............................................................
Y030_OSHVF/25-163                    ..................CKMNRIDSAFGGwLTNLTEVYYCPTHNIYHHCDGD.GTCIIV.N.--.--.SVCTRSGTCM.GISTL......---------...--------.....--------.-..------------------------------.-------------------------....--------------------------------------------------vgvthdlmdidslpafdrfklrmmnkgyfwismqdrlkeeleeaksgdegmtmethfrnkpdvestltrlyyyfkrelgmit
UL92_EHV2/81-274                     ..................CYYARVESLICA.LHGVSSLYVCRACENYHVCDGG.DECIVV.N.TG.DN.MVCFLTGNCV.ADNIQ......--DFCDLNI...AVKKKEMEcaptdDYNTFLGI.A..EAIKKDIFTFFNREDGKLAEIREAILTEGG.LRPEIGRLIEVTLRVSIHIFSKSDH....GYDVICSMYVQIIISIYSTKTVYNGLLFKCTKNKRYDSVLKKMRELWMST..................................................................................
UL92_EBVA8/25-220                    ..................CSYSKLEFHLPL.PESMASVFACWGCGEYHVCDGS.SECTLI.E.TH.EG.VVCALTGNYM.GPHFQ......--PALRPWT...EIRQDTQDqrdkwEPEQVQGL.V..KTVVNHLYHYF-LNENVISGVSEALFDQEGaLRPHIPALVSFVFPCCLMLFRGASSe..kVVDVVLSLYIHVIISIYSQKTVYGALLFKSTRNKRYDAVAKRMRELWMST..................................................................................
I1LIG1_SOYBN/216-317                 ............hacsge---------TCS.YYHIGDVFICEKTGQVHVCDDT.CRELVM.D.PT.NGlLVCTISGHCL.DRLLS......PSEEMEPDT...EQQQGGVA.....D-------.-..------------------------------.-------------------------....--------------------------------------------------eaepfmgsgrfarayllgyncadeke........................................................
UL92_HCMVM/8-194                     ..................CDMRHVQNAFTE.EIQLHSLYACTRCFRTHLCDLG.SGCALV.S.TL.EG.SVCVKTG-LV.YEALYp...vaRSHLLEPIE...EAALDDV-.....------NI.I..SAVLSGVYSYLMTHAGRYADVIQEVVERDR.LKKQVEDSIYFTFN---KVFRSMHNvnriSVPVISQLFIQLIIGIYSKQTKYDACVIKVSRKKREDALLKQMRSEYGNA..................................................................................
S8C2M3_9LAMI/81-177                  .........vinhvcsge---------SCT.YYTIGDVFVCEKTGNVHVCDDTcKEIIMD.P.MN.EL.LVCTISGRCF.DSLIS......---------...--------.....--------.-..------------------------------.-------------------------....--------------------------------------------------paemgtdpeqeegcvmdeaepfmgsgrfarayllgy..............................................
A0A067KI94_JATCU/210-286             .............hacsg--------EMCS.YYQIGDVFVCEKTGNVHVCDET.CRETVI.NpVN.EL.LVCTISGLCF.DRL--......---------...--------.....--------.-..------------------------------.-------------------------....--------------------------------------------------vspyemepdpaegavadeaep.............................................................
M1BKZ1_SOLTU/45-132                  ............hacsge---------TCA.YHQIGDVFVCEKTGNVHVCDDT.CREVVL.DpTN.GL.LVCTISGHCF.DSMLL......SPDEMEPDV...DQQQAG--.....--------.-..------------------------------.-------------------------....--------------------------------------------------ttdeaeplmgsglfa...................................................................
L1I894_GUITH/161-258                 ............idfdla------------.--------GCTECGAIHRCDA-.ATCPVF.E.EE.DS.HVCTITGNCVrLKRFT......HDEFMDNVV...ISDL----.....--------.-..------------------------------.-------------------------....--------------------------------------------------pgpveremrlltderevrenvewllssrtarqsfeqerg...........................................
UL92_SHV21/6-195                     ..................CQFNKLNTVVCQ.YHKVFCLYQCCQCKKYHICDGS.KTCILI.N.TG.ES.LVCTLTGNCI.FNNFQ......ENTFLKQDN...IKESKQQF.....DFTLFANI.L..ESLKQDLENYFIKSYG-LEEVSKAILDNNS.LKPEICDLIRCTFQHCCHIFGEIQY....GYDIICSMYIHIIISIYSTRTVYGNLLFKCTKNKKYDYILKRMRETWMST..................................................................................
X6P7N8_RETFI/39-171                  kaileafeksrqpktvvi------------.----------------------.------.-.--.--.----------.--TVE......EDEKMKAME...KKMEDLRQ.....KEKEVKET.I..KKVKEKGEQSKSKINEEIEKLIEKIIKRKKeLIALVDSTVSTKLQMMQSLLSVLDK....SFQSLQNTYTYVVIRTYSIRTMFEK-------------------------ygiaq.............................................................................
A0A0B0PFQ7_GOSAR/216-318             ............hacsge---------TCT.YYQIGDVFVCEKTGQVHVCDDTcREVILD.P.NN.EL.LVCTISGHCF.DRLLS......PSE------...--------.....--------.-..------------------------------.-------------------------....--------------------------------------------------meldaeqqqaggtdeaepflgsgrfarayllgyncedekele........................................
A0A059C2U5_EUCGR/351-456             ............hvcsge---------TCS.YHQIGDVFVCEKTGNVHVCDET.CRETVM.DpAN.EL.LVCKISGHCL.DRLLS......AA-EMETDA...EQQQGGV-.....--------.-..------------------------------.-------------------------....--------------------------------------------------tdeaepfmgsgrfarayvlgyncadereldavl.................................................
A0A0D2TAM3_GOSRA/164-266             ............hacsge---------TCT.YYQIGDVFVCEKTGQVHVCDDTcREVILD.P.NN.EL.LVCTISGHCF.DRLLS......PSE------...--------.....--------.-..------------------------------.-------------------------....--------------------------------------------------meldaeqqqaggtdeaepflgsgrfarayllgyncedekele........................................
UL92_EBVB9/25-220                    ..................CSYSKLEFHLPL.PESMASVFACWGCGEYHVCDGS.SECTLI.E.TH.EG.VVCALTGNYM.GPHFQ......--PALRPWT...EIRQDTQDqrdkwEPEQVQGL.V..KTVVNHLYHYF-LNENVISGVSEALFDQEGaLRPHIPALVSFVFPCCLMLFRGASSe..kVVDVVLSLYIHVIISIYSQKTVYGALLFKSTRNKRYDAVAKRMRELWMST..................................................................................
L1IIQ9_GUITH/59-165                  .......crwqcidfdla------------.--------GCTECGAIHRCDA-.ATCPVF.E.EE.DS.HVCTITGNCVrLKRFT......HDEFMDNVV...ISDL----.....--------.-..------------------------------.-------------------------....--------------------------------------------------pgpveremrlltderevrenvewllssrtarqsfeqergrmeq.......................................
D7TFB9_VITVI/198-280                 .............hncsg--------VTCT.YYQIGDVFVCEKTGRVHVCDDT.CREVVT.D.TA.NDiVVCTISGHCF.DRLLV......---------...--------.....--------.-..------------------------------.-------------------------....--------------------------------------------------sdeepdieqqqggvtdeaepfmgsg.........................................................
UL92_HHV8P/1-188                     ..................--MKSVASPLCQ.FHGVFCLYQCRQCLAYHVCDGG.AECVLL.H.TP.ES.VICELTGNCM.LGNIQ......EGQFLGPVP...YRTLDNQV.....DRDAYHGM.L..ACLKRDIVRYL-QTWPDTTVIVQEIALGDG.VTDTISAIIDETFGECLPVLGEAQG....GYALVCSMYLHVIVSIYSTKTVYNSMLFKCTKNKKYDCIAKRVRTKWMRM..................................................................................
L1I6P4_GUITH/89-198                  .....dcsdqrtididla------------.--------GCRECGAIHRCDAS.-SCPVS.E.EN.DS.HVCLITGNCVrMKRFT......RDEFMDSVV...IMDLPEAM.....DREVKLLVeM..REVKDKVEWILMS-----------------.-------------------------....--------------------------------------------------stalqsfdqergrmeqk.................................................................
#=GC seq_cons                        .............tssst.........hCs.YaplGsVFlCE+TGpVHVCD-o.scshlh.s.ss.-h.lVCTISG+Ch.cphls.......sp.hcs.............................................................................................................................................t..t....t.t......................................................................
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