GenomeNet

Database: Pfam
Entry: Imm1
LinkDB: Imm1
Original site: Imm1 
#=GF ID   Imm1
#=GF AC   PF14430.3
#=GF DE   Immunity protein Imm1
#=GF AU   Iyer LM, Zhang D, Aravind L
#=GF SE   Manual
#=GF GA   22.40 22.40;
#=GF TC   23.60 22.60;
#=GF NC   22.30 22.10;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 11927849 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   21890906
#=GF RT   Evolution of the deaminase fold and multiple origins of
#=GF RT   eukaryotic editing and mutagenic nucleic acid deaminases from
#=GF RT   bacterial toxin systems.
#=GF RA   Iyer LM, Zhang D, Rogozin IB, Aravind L;
#=GF RL   Nucleic Acids Res. 2011; [Epub ahead of print]
#=GF DR   INTERPRO; IPR025680;
#=GF CC   A predicted immunity protein, with an alpha+beta fold and a
#=GF CC   conserved C-terminal tryptophan residue. The protein is present
#=GF CC   in a wide range of bacteria in polymorphic toxin systems as an
#=GF CC   immediate gene  neighbour of the toxin gene [1].
#=GF SQ   44
#=GS C6WEA3_ACTMD/12-136     AC C6WEA3.1
#=GS F2R351_STRVP/15-142     AC F2R351.1
#=GS A4FBS3_SACEN/82-214     AC A4FBS3.1
#=GS K0JYL2_SACES/13-134     AC K0JYL2.1
#=GS K9UIU5_9CHRO/14-133     AC K9UIU5.1
#=GS B5I5L9_9ACTN/8-159      AC B5I5L9.1
#=GS B5HTM6_9ACTN/15-133     AC B5HTM6.1
#=GS U5W411_9ACTN/10-130     AC U5W411.1
#=GS K0KBD0_SACES/57-185     AC K0KBD0.1
#=GS C6WKC5_ACTMD/12-132     AC C6WKC5.1
#=GS C6W949_ACTMD/11-136     AC C6W949.1
#=GS K0JS46_SACES/13-136     AC K0JS46.1
#=GS H8MZ31_CORCM/17-131     AC H8MZ31.1
#=GS I4D0E2_DESAJ/2-101      AC I4D0E2.1
#=GS Q0RT11_FRAAA/4-71       AC Q0RT11.1
#=GS A4XC98_SALTO/9-141      AC A4XC98.1
#=GS C6WEX3_ACTMD/18-134     AC C6WEX3.1
#=GS D9T1U3_MICAI/14-138     AC D9T1U3.1
#=GS E6UAV8_RUMA7/21-135     AC E6UAV8.1
#=GS C6WSI1_ACTMD/16-134     AC C6WSI1.1
#=GS H5X661_9PSEU/17-138     AC H5X661.1
#=GS R5GY51_9FIRM/7-118      AC R5GY51.1
#=GS C6WBV0_ACTMD/12-128     AC C6WBV0.1
#=GS C7PIU5_CHIPD/14-129     AC C7PIU5.1
#=GS C6WG35_ACTMD/11-130     AC C6WG35.1
#=GS K0JQV7_SACES/9-143      AC K0JQV7.1
#=GS A8FFG7_BACP2/74-126     AC A8FFG7.1
#=GS C7MR24_SACVD/1-72       AC C7MR24.1
#=GS K9QXE7_NOSS7/17-162     AC K9QXE7.1
#=GS A0A023Y3X1_9GAMM/6-122  AC A0A023Y3X1.1
#=GS H5X666_9PSEU/12-139     AC H5X666.1
#=GS K0JTT1_SACES/13-135     AC K0JTT1.1
#=GS K0JWW8_SACES/18-145     AC K0JWW8.1
#=GS H5X373_9PSEU/13-123     AC H5X373.1
#=GS G0G1V8_AMYMS/19-138     AC G0G1V8.1
#=GS A4F912_SACEN/17-136     AC A4F912.1
#=GS C6W9F0_ACTMD/13-134     AC C6W9F0.1
#=GS Q9ACV1_STRCO/8-162      AC Q9ACV1.1
#=GS F6AK94_PSEF1/2-100      AC F6AK94.1
#=GS D2PZU9_KRIFD/8-125      AC D2PZU9.1
#=GS H5X8S8_9PSEU/13-123     AC H5X8S8.1
#=GS B2J6J2_NOSP7/17-130     AC B2J6J2.1
#=GS C6WDT1_ACTMD/11-134     AC C6WDT1.1
#=GS C6WF04_ACTMD/14-137     AC C6WF04.1
C6WEA3_ACTMD/12-136                ..........................................q-DDGEIVSTPDDLDRVLDVLAGRE..GR----..LLLDLHLAGDPGGPS.......................LEVG.......VNSAGQLGSLNYTKGWe..........................eNWLSTSSPESPQ.PHEEHILYYYMMSDT.EY.PADC.EIPLDVVRRAAHEFMRT.gGERPT.EPRWR-a......
F2R351_STRVP/15-142                ..........................................m-HEPVLVAIEDDVDSLIDALLA--..-GPPFH..DAAHLVSRARPMTGLgfp.................dheLYVG.......VNRDAQVGALVLLAPE............................--TGFVASVGVL.GSQIEVVYHVAGHGT.EF.PADS.EIPLGLVRSAVKEFLHS.gGGVPT.CVVWKP.......
A4FBS3_SACEN/82-214                ..........................................d-GDRHYAQTDDDKATLVNRVLRPQ..SKRAA-..---HLFVWDRPFDNEeiag...............pyqqVRVV.......TDPEAEVGVLNYTEETee........................geL-RSWHTLNPQP.LPDPPALRFDAGSAL.RF.PRDS.VLPFRDLRAALLEYSRD..GLRPE.AVQWQS.......
K0JYL2_SACES/13-134                ..........................................g-STPLEITTHAELAELVDRVTR-L..TGGPVP..SIAEITVAEDPYGLP......................mLYVG.......IGEDR---GFVQELGN............................---PPRATVGDP.DATGDILFDYMANTQ.EV.PAWQ.VVPRETVITVLTAYLDH.dGLIPP.------dhphlrp
K9UIU5_9CHRO/14-133                ..........................................i-EEDITYPSWEKIILYLKMMNGCS..KHMMFLypDVNEIEDSE------.......................-FMS.......VCGGENNTFICTLHND............................--GTDSNKLVNA.DESSKETVMFYSGQTsGK.SKDR.IVDFEMVLKAIKTYVET..GQLDR.TLTWRN.......
B5I5L9_9ACTN/8-159                 ..........................................n-DRRWFAETDTEVSTVVAEVLGSL..QG----..-----WNKRGEHWHPgtiawfswsdrrhvsdadmpnnfLVVS.......LNRDSGYGGLIWFVNSgypgp..................etdevLDNIWVSDNPNP.PDFDTEVVSNPGEPY.WF.DPRS.TLPIEEIEAAVHEFCRVrtGIRPE.CVQWT-l......
B5HTM6_9ACTN/15-133                ........................................fsg---LERHSNVQDLEAHIKALGTGL..-GQGYL..EIRRPD----GDLPY.......................LALG.......FKGDH---AVLHLFDD............................-SGGVSLRGGDD.CVAPSAEVEVVIMDElHVfTADV.ALSMDHAWDIVHDFIQT..GTPGE.LNDWYE.......
U5W411_9ACTN/10-130                ..........................................d-EDGHLVTCEEEFRHALAEAEQDA..ARLPL-..-IADITVG---DGDC.......................LSIG.......LGRAISVLSYVRASKE............................PPYLISQGSARV.QDSEGVVFHYYGHWS.EF.PPSA.AVRVKDAVEAVRHFCEH..GELSS.LLTWVE.......
K0KBD0_SACES/57-185                ..........................................a-ADESTVDSPQDVDALLRRLAEPG..AGPAVIehQDRPLLDDTEGLLGApgqtk.............ipdhdVAAA.......IHAGF---GYLTYADPd.........................hdYSTLVGDPGSPE.YRSEYVDY-------.--.PAGT.GVPVEALGAALKDFLAT..AARPT.CVEWQN.......
C6WKC5_ACTMD/12-132                .........................................gr--SPVEVRTRAELDELVERVRALH..VGSPV-..-VVEFSVTGEEWSYP......................iLYAG.......IGRER---GFVQEHGH............................---PVRATLGDP.RAKGEVVYALATHAT.SV.PADQ.EVPLEAVREILAAYLAG.gGVIPP.------dhprmql
C6W949_ACTMD/11-136                ..........................................q-DDAVPVRTAAELDAVLDEVAAMR..GR----..VIVHLKVARPPSLDVrr...................miLNVG.......LNGDAGLGSLFYRSPS............................-GAWYSQGAAAD.PSVSELLYYYMNSDT.EY.PLDC.EIPIDAVRRAAHEYRSA.vDTRPS.APGWQP.......
K0JS46_SACES/13-136                .........................................gd--IPVTLSTVDEVDALLDRVRVES..PPAA-P..MLMDVHLSGDPYAQG.......................LDVG.......VAVDR---GVIRYSGR...........................eWPHGVVSTGDGS.ADGEPRSYFYMGHGR.EF.PANS.EVPIDVIRKAVKEFMES.nGARPT.CVRWQ-d......
H8MZ31_CORCM/17-131                ..........................................r-EEETDEPTWEQVERAFQSLDARR..HTMLT-..------LEADEEDHG.......................LI--.......VGGGGGLYVVTVHRYP............................---EIFTLTSAE.TDAGEAVRLTIGGQEgIF.AKNL.CVGVDQALLAMRRYFET..CELER.SMRWV-a......
I4D0E2_DESAJ/2-101                 ......................nsknqykqiwletedeqamca------------------------..------..---------------.......................---L.......INGDKGWLMYLRYNGD............................SGFSSRNPNYNG.DPRAVLEYYLDNGQCdEY.PLSW.TLPIVEVERALDYFKKE..KKPPK.FITWH-n......
Q0RT11_FRAAA/4-71                  .........................dndlirpftsnsqiwwsr------------------------..------..---------------.......................----.......----------------............................-----------G.EPRDEVDYWLGSQPS.YC.PPWA.LIPMATAQQVVRANFTT..GERPD.TVEWA-q......
A4XC98_SALTO/9-141                 ..........................................r-GNRRPGSTIAEVDTALNDAAASG..VPQVVGiyPPQHLAGDASPWDAPlp...................paLQIG.......VGHPD--RSFVLWLGPe..........................gGIGVEADAPPWP.DGTPDIAFDYGGDAVfAG.PDRA.RVTPDTARQAAREFVRT..GQRPT.CVQWTS.......
C6WEX3_ACTMD/18-134                ..........................................e-HRYRVVACPADVDLLIEALGAPG..CNDATLehFGRDTDDE-GECDHS.......................VVLA.......VRGAW---GYLHYVDPd..........................fSGWPVGDERAPH.VNEAYTDF-------.--.PPGV.GVPLEVLRALVLEFLAT..ARRPD.AVRWY-t......
D9T1U3_MICAI/14-138                .........................................dn--HEVELTDPDALGALLREIQQAG..EPVVL-..TIFSDTDNDPDDLPP......................gIQIG.......LGHPTH--AFAVHIAD............................-DGGYLNDPKAE.TPAEGLHFDFGGVPT.EY.PAEHlQLRPETAIQLAVTFLKT.gGEPPH.------laavte.
E6UAV8_RUMA7/21-135                ..........................................d-KGDITITDTDEIITLILDLAEKG..MN----..---EIWISEDNTSYPal...................avLVNGryaclnyFGNDN---GDMYMSRG............................------------.--KENVEVSFNPGGTeWVaPADA.VLPINTAIDCIRQFCKN..YKLPD.CIEWQN.......
C6WSI1_ACTMD/16-134                .........................................rp--GSWTASSSEEVSDALDRIFNSP..WEFRT-..--------------E.......................CVIR......iAGLRTGLRVLVYLKDGrt.......................tllWAGTHRSKNPTPfPDAPLIAEDRDSETPlHL.RRDS.YLSRESARSAVLEYLAT..GERPT.CIEWQP.......
H5X661_9PSEU/17-138                ..........................................e-GKNTTLRTPQDVAAFAARVAAADpyADSIRVihNDRPLADAEQGFTDH......................dVFAA.......VVDGF---GYLSHQDQd.........................ntKAFPVGDPDSAG.CEFDDEDF-------.--.PAGS.GLPLDQFTTALVEFLHT..TERPT.NVRWTS.......
R5GY51_9FIRM/7-118                 ngnfpaedaeqlkaalnaacgeiwlgegtdsypcvailccedg------------------------..------..---------------.......................----.......----A---SINYFESE............................-GGTAYVSVGDR.KKHGTTDVNIDGEMY.QL.DRGQ.IVPQEKILDIAVEFMND..MKLPA.CVEWE-k......
C6WBV0_ACTMD/12-128                ........................................qtv---DAELRGPQDVDGVLDDLVRVG..GP----..VMAQLWDRSDPASTL.......................LNVG.......VDGPRGCGLLCHVDGD............................---EVWISEGTG.EPGRYLMIGLDWDH-.--.PAGV.EVPLAVVRAAVHEYARG.gGRRPG.GVRWR-l......
C7PIU5_CHIPD/14-129                .........................................ys--NDKDIKESYEAVTALQTLNGKN..VTQ---..---------------.......................LIVGdingfilIGGGPELFVVTQVVGE............................DEAFFNLINPEC.VSDEEEISLVTGGQAgGF.PKKN.CVPLALAEQALTYYVKH..GDRSP.SLRWEE.......
C6WG35_ACTMD/11-130                ..........................................s-DEPAIVGTPEELDRVLDVAVGWG..WR----..AIVELFVVGSPKRAI.......................FGVG.......VHGRAGVGMLCYSDAR............................---GKWRTLGGE.AVTGQILYCYMNADT.EF.TADC.EIPLDLVRQAAHEYMSS.gGARPT.VVDWQP.......
K0JQV7_SACES/9-143                 ..........................................n-GTACVASGKSECVLLIDRILGAN..ETQWEStlSIGDVEYRKDRDGGPfp..................nhqLRIS.......VDSAAGFAAINYLDND...........................dLKMPVANSYNPK.RPPPDLSLIFNGTTGaLF.PRSA.AILISDARRALIEWIET..RQRPK.CIEWMP.......
A8FFG7_BACP2/74-126                ......................................fkkge------------------------..------..---------------.......................----.......----------------............................------------.--KIETIEHFVAGAPlYV.PSCS.YVDRNQAYQIVHHFLTT..KTVPD.LVEWVE.......
C7MR24_SACVD/1-72                  ........................................mfa------------------------..------..---------------.......................---A.......VVDGS---GYLSHQDSn.........................haKAYPVGVPESPG.CEFDDEDF-------.--.PAGS.GLTLEQFTAALVEFLHT..TKRPT.NVRWA-t......
K9QXE7_NOSS7/17-162                .......................................eetv----IENPNWQQIKTAICELDGKI..KTLVS-..----LEADDQ----S......................yMMIG.......GGNDGQYIVTVTLDNEifysllhpidyeisksdtsvkkinlsifYQALIKAKSNNT.NSANEQRLV-VGGQAgNY.SEKI.CVNLPQCLIAAITFAES..GELEA.LFTWEE.......
A0A023Y3X1_9GAMM/6-122             ..........................................n-GQSVAATTQAQVDAALARANTLP..AF----..---ELWAT-APTGATl....................cmLRNG.......VHAWL---MYIPVEGD............................---AGVRSCGDA.TRIGSADYVLGNGQVdTY.PLSW.CVAVEQCFSAVATFLHS.gGDKPE.GIVWL-a......
H5X666_9PSEU/12-139                ..........................................h-REPVALSTSAQVDELLNQMVAEA..ESPEVEvgLVAQLERKDDDGWSV.......................LQFG.......VRAAATMCGFVGYMAK............................-GEPSTISDNGG.TSPEPVAYDYQTHER.EV.PTNA.EITWPTVRQAVHDYVAS.gGARPD.GVRWRE.......
K0JTT1_SACES/13-135                ..........................................g-ARPVLIHTLVELDAFVERVRTLA..VAQECP..AVAEISHADNPWGHA......................iLEVG.......IGKER---GFVRENST............................---PMRATGTTT.EVADPIVYDDQGTGV.DI.PAGQ.EVPLDVVRRVLAAFLAH.dARIPE.------dspdlhv
K0JWW8_SACES/18-145                ..........................................a-EHPRAVQNVGELSEFIGSVIIDA..TRAGEN..IMMEVVTSESAYDHQ......................iLEVG.......ISSDGKR-GFVHVASD............................-DGPARLTRGDAsSDSTLAIYRFEGRAR.EV.PASH.EVPLTIVAEVLEIYLTT.dGNIPAdC-----phlhs..
H5X373_9PSEU/13-123                ..........................................q-GYDLELTAAADVDELIRLLYLDD..AGTASI..QRTEV-------DPV.......................LDVQ.......VHDRF---GYLMYVGDq..........................mYGYSVGDPDSPDlADLSEVGF-------.--.PAGT.GVPLERFRAALVEFITK.dGALPS.VVEWRP.......
G0G1V8_AMYMS/19-138                .........................................eg--ATTTVDTVDELNNFIDEVLDET..EGYAVP..PMIQVAVSGDYNAPV.......................LDVG.......LGPEY---GFIQCLSA............................---DGGWSLGDA.KCTGHVTYDYMAHAR.EI.PANA.EIPLEQVRVAMEQFLTT..GTKPK.AISWQ-q......
A4F912_SACEN/17-136                ..........................................a-GDGLTIDEPDQVDELIRRLAEPA..AGPATIwhEGRKLADTGSGMLDH......................dVVAA.......VRGGYGYLGYIDADHD............................YAVLAGDPASPE.VHAEDADF-------.--.PAGS.GVAPEQLAAALREFLAT..GLRPE.NVTWRE.......
C6W9F0_ACTMD/13-134                ..........................................g-ANPVLIETQEDLDALVERVRERS..TGHPCP..SIVEISDAADPWGSP......................tAYAG.......IGNDR---GFVQVHDD............................---PMRATRGRA.GTTGTVVYDLVANAT.DI.PADQ.EVPLDVVRAVLAAYLAH.nSRIPA.------dhplln.
Q9ACV1_STRCO/8-162                 ...........................................HAGEIYARTKEEVDSLIDHIMSDL..IQAGE-..-----TPDGFEIIPEravlsvvegkypeetderwpsnyLYIS.......LNTTEGYGALKWWTSVvsdga..................reddvSRFVWTSGNQNP.PSSDPRLIADPGTPS.YY.PRQA.AIPSHQVREVLEEFCRAgtGARPG.CIPWL-l......
F6AK94_PSEF1/2-100                 .......................eespfrevwieipdgqsmca------------------------..------..---------------.......................---L.......INGEWGWLMYLRYNGD............................AGFSSRSTNYKG.PTESTIEYRLNNGQHdEY.PASW.AYPVDVIERALHFFQAQ..QTPPA.FIHWH-n......
D2PZU9_KRIFD/8-125                 ..........................................d-AGQERIGSQAELDEVLDRVASLP..RPTWVE..LVSADELA-----T-.......................MNIG.......LGAAF--SSLTLYDDV............................DGSAEYRSAGTL.DEPQEATFDYGAVPT.TM.SKGK.AMTVKDARAAASEFFAT..GRRPE.LVAWE-l......
H5X8S8_9PSEU/13-123                ..........................................a-HHELPVSTPDDVDELLTVLDRDD..VHTVT-..------VRDGEEDPA.......................LDVQ.......VHGGY---GYLLYAGEe..........................lLAYSVGDPDSPAlTDRSESAF-------.--.PAGS.GVPLEALRAALREFVDT.gGSVPS.SVAWQE.......
B2J6J2_NOSP7/17-130                .........................................kg--CVEQAHSWQEIESAIRELDGHH..KTLVTL.eTDSETH---------.......................MAVG.......GGLGK-YIVYLTFDNE............................----SFHYLVDP.SKSDMNEFVIVGGQEgVY.PAKS.CVDLDATLKAAKAFAEL..GTMEE.SVNWE-k......
C6WDT1_ACTMD/11-134                ..........................................r-GKPILAASVAELDAAIDLISGDS..ARQECP..SMVEITIEEDPYGHA......................yIDAG.......IGVEQ---GFVHLNGP............................--DTYRTTVGDP.NAAGTVLYDCCGNGE.DV.PARE.EVPLATVHAVLAAFLAH.dGLIPD.------dhpdlhl
C6WF04_ACTMD/14-137                ..........................................g-KEPLFLHTPDEVRAWFARWREAS..PAGSV-..DLATFYLAGDDWGPE.......................LNAG.......LDGDK---GVLHHSGDd..........................dTSYGFHSRNPQG.SNPDEVVYYFFAADT.PF.PPHS.EIPVTDVESAVLEFMST..GLRPT.RVHWQ-a......
#=GC seq_cons                      ..........................................s.tp.h.hps.t-lsthlpplht.t..ht.........ph..ttt............................l.hu.......lssst...uhlhhpss..............................hshtssssss.ssssphha.h.sttt.th.Psss.tlPl-psppAlpcFhps..GphPs.slpWp........
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