#=GF ID   Imm12
#=GF AC   PF15560.10
#=GF DE   Immunity protein 12
#=GF PI   Imm8;
#=GF AU   Zhang D;0000-0001-8535-7620
#=GF AU   de Souza RF;0000-0002-5284-4630
#=GF AU   Anantharaman V;0000-0001-8395-0009
#=GF AU   Iyer LM;0000-0002-4844-2022
#=GF AU   Aravind L;0000-0003-0771-253X
#=GF AU   Finn RD;0000-0001-8626-2148
#=GF SE   [1]
#=GF GA   25.00 25.00;
#=GF TC   25.40 25.10;
#=GF NC   23.10 21.70;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 75585367 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22731697
#=GF RT   Polymorphic toxin systems: comprehensive characterization of
#=GF RT   trafficking modes, processing, mechanisms of action, immunity
#=GF RT   and ecology using comparative genomics.
#=GF RA   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL   Biol Direct. 2012;7:18.
#=GF DR   INTERPRO; IPR029088;
#=GF DR   SO; 0100021; polypeptide_conserved_region;
#=GF CC   A predicted immunity protein with an alpha+beta fold and several
#=GF CC   conserved charged and hydrophobic residues. Proteins containing
#=GF CC   this domain are present in bacterial polymorphic toxin systems
#=GF CC   as an immediate gene neighbour of the toxin gene, usually
#=GF CC   containing a domain of the Tox-URI2 family [1]. The protein is
#=GF CC   also found in heterogeneous poly-immunity loci.
#=GF SQ   11
#=GS J4KA06_9FIRM/36-168     AC J4KA06.1
#=GS D3IHH0_9BACT/1-138      AC D3IHH0.1
#=GS A0A0F5IK84_9BACT/1-133  AC A0A0F5IK84.1
#=GS A0A1G7HE41_9FLAO/1-128  AC A0A1G7HE41.1
#=GS D7JGN5_9BACT/1-138      AC D7JGN5.1
#=GS A0A3E2YJL5_9ACTN/4-86   AC A0A3E2YJL5.1
#=GS Q73QB3_TREDE/1-138      AC Q73QB3.1
#=GS H1PIZ3_9FIRM/1-133      AC H1PIZ3.1
#=GS A0A2S8AFU1_9FLAO/1-133  AC A0A2S8AFU1.1
#=GS S5ZMD2_9SPIR/1-138      AC S5ZMD2.1
#=GS A0A0A0X792_9SPIR/1-138  AC A0A0A0X792.1
J4KA06_9FIRM/36-168                mkvnmniivggtddilddil------------------------SAARTVRKEMKNIFESVETETLQKMDICVCLSGNISKYYPKSGIYQARYYSKAKKFMVYVHFSSNEWNS....KKTESVS-KFLKMYKDYLMELSDIIKTKTTKYKPDFDSRCYE---dgi.............
D3IHH0_9BACT/1-138                 ....................MEIVISSVIGGQIAAVEGLEKVVHALIIEMRKSFKKQFENKSFAGLDKVKINMYISGDVSEYCTTSEITKCLYFERKKQFISEFCIARSYWTS....CSLSDVKGKFLLLIENLFVSLSMLIKHRLKCKGYDFDSEVFKEIV................
A0A0F5IK84_9BACT/1-133             ....................MEFTLNIVYGGELNA----SKALSPFVRNMRKIIKDTFTSFENEAVTMFKVTLFFDGDISSYYNGTGIYQPRYYNVKKEYVVSFCIDRTQWTG....NKEKDLN-YFIFTITSLMIKNGDLILNKLAKYKYAFDINSYKHCV................
A0A1G7HE41_9FLAO/1-128             ....................MEVTLTSQIGG-----LDAGEVFRPINIQLRRSLKL-ITDNYSEIIDHFKLQMRVSGSVTVYKEDTGVHYLRVMKKLKYISGEIILGKEVWENktntEIVISVSEYVVLLFENLIAKL------------------------kqqqididgvrllddv
D7JGN5_9BACT/1-138                 ....................MEIIVSSVIGGQIVAEVGMERVLHQLIIEMRKSLKKQFANNSFDGLDKTKINIYVSGDVSEYCTKSGITKCRYLREKKEIISEFCIDRYYWTS....EPLLDVKRKFLLFIEDSFVDLGVCIKKKLKSEGYDFDSEVFKEMV................
A0A3E2YJL5_9ACTN/4-86              ....avrvrlggperalaep---------------------------VALRRALKESFGRIVIDGLDEVDIFLTLGGSITSAEGDGGVHNLRYSAVRRRLTVNVV--------....---------------------------------------------vpaseigrd.......
Q73QB3_TREDE/1-138                 ....................MEVILSTVIGGEITVEVDGGKIVHSLIIKMRNSLKEHFKKIFFEGLDRIKINVYISGDVSSYCDKTGITATRYFRAKTEYTTEFCIDKNYWSL....EPVLPVDRKFILFMENSLIQLGGIIEKKLKAAGYNFDGELFKEIV................
H1PIZ3_9FIRM/1-133                 mkvnmniivggtddmlddil------------------------SVARTVRKEMENSFESIEIETLQKMDICLCFSGNISKYYPESGIYQARYCSKTKNFMVYVHFSSNEWGS....NKKESVS-KFLKMYNDYLLELSDIIKMKMAKHKSDFDNKCYEDM-i...............
A0A2S8AFU1_9FLAO/1-133             ....................MDIYLNSAFGGESKA----KNTLFSLNIVIRKSLKKVFNDFHIEKVKEIEFYLGFNGDLTKYKETSGIYSPRYSSKKESFVVNIIFDDTKWGD....NQI-ENKRIFITELETYFFDAGVILNNKLKKIKIEFNLNEYK---ari.............
S5ZMD2_9SPIR/1-138                 ....................MEIILSAAIGGEITADCDGGKTVHSSIIKMRKSLKEGFKKIFFEGLNRIKINLYIGGDVSAYCDKTGITVTRYSHTKKECAAEFCIDKKYWTS....APVLPIKKKFILFIEKSLISLGEIIGKKLKAAGCDFDCKLFKETV................
A0A0A0X792_9SPIR/1-138             ....................MEVILSTVIGGEITVEVDGGKIVHSLIIKMRNSLKEHFKKIFFEGLDRIKINVYISGDVSSYCDKMGITATRYFRAKTEYTTEFCIDKNYWSL....EPVLPVDRKFILFMENSLIQLGGIIEKKLKAAGYNFDGELFKEIV................
#=GC seq_cons                      ....................MElhlssshGGp..s....tchlpulhIphRKSLKcpFpsh.hEuLc+hKIslhlSGDlSpYpscoGIppsRYhppKKcassphsls+shWss....p.l.sVptKFlhhhEs.hlpLuslIppKLpththsFDschaKch.................
//