GenomeNet

Database: Pfam
Entry: Imm24
LinkDB: Imm24
Original site: Imm24 
#=GF ID   Imm24
#=GF AC   PF15570.1
#=GF DE   Immunity protein 24
#=GF AU   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L, Finn RD
#=GF SE   [1]
#=GF GA   23.40 23.40;
#=GF TC   24.10 27.00;
#=GF NC   22.00 22.60;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 23193494 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22731697
#=GF RT   Polymorphic toxin systems: comprehensive characterization of
#=GF RT   trafficking modes, processing, mechanisms of action, immunity
#=GF RT   and ecology using comparative genomics.
#=GF RA   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL   Biol Direct. 2012;7:18.
#=GF CC   A predicted immunity protein with an alpha+beta fold with
#=GF CC   conserved tryptophan, proline, aspartate, serine and arginine
#=GF CC   residues. Proteins containing this domain are present in
#=GF CC   bacterial polymorphic toxin systems as an immediate gene
#=GF CC   neighbor of the toxin gene, usually containing a domain of the
#=GF CC   Tox-AHH family of HNH/Endonuclease VII fold nucleases [1]. The
#=GF CC   gene for this toxin is also found in heterogeneous polyimmunity
#=GF CC   loci.
#=GF SQ   23
#=GS G3Z7E6_9NEIS/45-151  AC G3Z7E6.1
#=GS F0P2G1_WEEVC/60-188  AC F0P2G1.1
#=GS C9KYL0_9BACE/42-171  AC C9KYL0.1
#=GS D3V9F5_XENNA/29-154  AC D3V9F5.1
#=GS A6EH29_9SPHI/41-171  AC A6EH29.1
#=GS F0R495_BACSH/44-176  AC F0R495.1
#=GS Q7N9I7_PHOLL/44-169  AC Q7N9I7.1
#=GS B3JGR8_9BACE/42-172  AC B3JGR8.1
#=GS Q7N9J9_PHOLL/44-169  AC Q7N9J9.1
#=GS E8JZG8_9STRE/45-151  AC E8JZG8.1
#=GS B3JEH9_9BACE/42-172  AC B3JEH9.1
#=GS E8JZH1_9STRE/45-159  AC E8JZH1.1
#=GS D3V9F2_XENNA/1-47    AC D3V9F2.1
#=GS D3V4E5_XENBS/29-154  AC D3V4E5.1
#=GS D1PUV2_9BACT/2-127   AC D1PUV2.1
#=GS D3V9F4_XENNA/1-69    AC D3V9F4.1
#=GS F0R8L6_BACSH/44-176  AC F0R8L6.1
#=GS C9KYL2_9BACE/42-171  AC C9KYL2.1
#=GS E2N0J6_CAPSP/41-170  AC E2N0J6.1
#=GS F0R3S8_BACSH/42-171  AC F0R3S8.1
#=GS Q64WI8_BACFR/54-183  AC Q64WI8.1
#=GS G2Z5Q2_FLABF/39-169  AC G2Z5Q2.1
#=GS D1YPM9_9FIRM/45-151  AC D1YPM9.1
G3Z7E6_9NEIS/45-151             ....f-DFPWS......WFLKGQKIP.......PMPEQVY-ICLKKARDVTFDFL.PYN.DFFIMSARFLEFIKKYGFSHNFGMSKVIIVNTKGE.LLT.NETYYLIRIIDW-------------.--EIEDEI.........-.V..YPDLELDEEDf......................................
F0P2G1_WEEVC/60-188             ...fv--FPWV......GATPVKDVA.......AMPEEVV-ICLKKVKGVHFDLL.VYN.NFFIVSEKLYEYMVINGFNYENGKSIAHILDTKGK.KLT.EEKFYLLRFYWWE------------.--------.........-.-..----------itteevgiftsedesshpraithssknflmttqlgyene
C9KYL0_9BACE/42-171             ..nlg---QWM......WQNNDGWRE.......NLPPVLYLVCNKKPGILQFDFLdKSSiELKIVSEEFLSLLQENGFIDKYDIATVKVVNKKNE.SLT.DKKYYALRINHFDNDSFHFGKGITY.QSDFQKKLg......tcFtV..YPDMKLKDI-si.....................................
D3V9F5_XENNA/29-154             ....v-NKNWD......YEGSDYSFPydm.eqpDCPEKLFLLCNRNIGALKFNYY.RHS.RAHLMSDYFFDFLKPFRMSDFICKKLLATSIKDGE.TIR.DDLNY---IYFTNNDDFLDFDKSKL.EEDRYRGV.........-.I..PHKLVFSEKVl......................................
A6EH29_9SPHI/41-171             ....n-TVQYE......WMKAGFNDY.......QLKSELS-LY-SKHEYLDFDYY.RYA.NDFLVSEDFLNAIAQYNI--DYEKSAVRVFSAVGNlELKfRKKYYFVKFRYA-EDVVNF-ELSTF.EDALSDKAepiihngvrY.VknYENIVLHEDRi......................................
F0R495_BACSH/44-176             ....y-SNDWF.....nYSPMRAGKPvpltdnyKLPTHFYWIC-SNVKRLETDYY.SHS.KGVILSSCLFEFLKQFKCYDKYDICEVTPVSRKLA.PIS.DKKYYFIRFKHLSYNQFIDLENSNR.IKRMNKVIt.......sY.L..YLDFRLREQTa......................................
Q7N9I7_PHOLL/44-169             ....i-NEKWD......YEGSRHDIPyyl.ldkECPNTLYLLCNKNIGKLWFNYY.QHN.MAHILSDRFFDIINEFKLSDHVLKKLIATSIKDGK.TIN.NSLNYLF---FTDKELFLNEKYSIL.EKDKYGNL.........-.I..PHKLSFHNESl......................................
B3JGR8_9BACE/42-172             ....t-KWRWM......WKDKNGWEE.......NLPPVLYLVCNKKPGILQFDFCdQWSiKLKIVSEEFLSLLQENGFIDKYDIATVKVVNKKNE.SLT.DKKYYALRINHFDNDSFHFGKGITFhQNDVEKKLg......isFtV..YPDMKLKDNSi......................................
Q7N9J9_PHOLL/44-169             ....i-NEKWD......YEGSRHDIPyyl.ldkECPNTLYLLCNKNIGKLWFNYY.QHN.MAHILSDRFFDIINEFKLSDHVLKKLIATSIKDGK.TIN.NSLNYLF---FTDKELFLNEKYSIL.EKDKYGNL.........-.I..PHKLSFHNESl......................................
E8JZG8_9STRE/45-151             ....f-DFPWS......WFVKGQEIP.......PMPEKVY-VCLKKARGVTFDFL.PYN.DFFIMSARFLEFIKKYGFDHDFGMSKAIIVNTKGE.LLT.NEVYYLVRIVDW-------------.--EIQDEI.........-.V..YPDLALDED-dy.....................................
B3JEH9_9BACE/42-172             ....t-KWRWM......WKDKNGWEE.......NLPPVLYLVCNKKPGILQFDFCdQWSiKLKIVSEEFLSLLQENGFIDKYDIATVKVVNKKNE.SLT.DKKYYALRINHFDNDSFHFGKGITFhQNDVEKKLg......isFtV..YPDMKLKDNSi......................................
E8JZH1_9STRE/45-159             ....f-DFSWS......WFVKGQEIP.......PMPEKVY-VCLKKARSVTFDFL.PYGyNFFIMSARFLEFIKKYGFNYNFGMSEAIIVNTKGE.LLT.NEVYYLVRIVSWE------------.--------.........-.-..----------iedeivypdlgrdekgfsleaytn...............
D3V9F2_XENNA/1-47               ..mrl------......---------.......----------------------.---.-----------------------------------.-IR.DDLNY---IYFIGNDDFLDLNNSEL.EEDRSGSL.........-.M..PHKLIINNPSn......................................
D3V4E5_XENBS/29-154             ....v-NENWD......YEGSDYSFPyym.kelECPNSLFLLCNRNVGALNFNYY.FHG.SGHIASNKFIDFFNELKTCEIISKNLIATSIKDGS.VIR.DDLNYLY---FIGNDDFLDLNNSEL.EEDRSGSL.........-.M..PHKLIINNPSn......................................
D1PUV2_9BACT/2-127              ....h-EFKWS......PNLPANEENi....frTMPQVLYLFINTKRKEPTFDYL.YIQdGIWAISEFFLKYLREN-IGSQIEAVPLKVYNKNRE.E-A.QRVYYAMRVHAFNDKLFDFHVESKK.RTAGIKNY.........Y.L..YPDMELKETNe......................................
D3V9F4_XENNA/1-69               ...mk------......-------EL.......ECPDSLFLLCNRNVGALNFNYY.FHG.SGHIASNKFIDLFNGLKTCKIISKNLIATSIKDGS.VIN.-------------------------.--------.........-.-..----------ls.....................................
F0R8L6_BACSH/44-176             ....y-SNDWF.....nYTPMRAGKPvpltdnyKLPAHFYWIC-SNVKKLGTDYY.SHS.KGVILSSCLFEFLKQFNCYDEYDICEVTPLSRKLA.PIS.DKKYYFIRFKHLAYNLFIDLENSNR.IKRMNKVIt.......sY.L..YLDFQLREQTv......................................
C9KYL2_9BACE/42-171             ...nh--GQWM......WKNKDGWRE.......NLPSVLYLVCNKKPGILQFDFLdKYSiKLKIVSEEFLSLLQENGFVDKYDIATVKVVNKKNE.LLT.DKKYYALRINHFDNDSFHFGKGITY.QSDLQKERg......tcFtV..YPDMKLKDSSi......................................
E2N0J6_CAPSP/41-170             krgew-----IkyspmyFSFPPEEKY.......KLPEELI-LVVKRQKEVLFDFLgYYE.GIRVFSDRLLNLLIENDLNLQFEKATLNVVNTKGE.NIA.KQPYYLLRFCRADNELFAFNENSKIaARDWEDTF.........-.L..YPDLHLKEPTd......................................
F0R3S8_BACSH/42-171             ...dh--GQWM......WKNKDGWRE.......NLPPVLYLVCNKKPGILQFDFLdKYSiKLKIVSEEFLSLLQENGFVDKYDIATVKVVNKKNE.SLT.DKKYYALRINHFDNDSFHLGKGITF.QNDVEKKLg......isFtV..YPDMKLKDNSi......................................
Q64WI8_BACFR/54-183             ...nh--GQWM......WKDKNGWEE.......NLPPVLYLVCNKKPGILQFDFLdKYSiKLKIVSEEFLSLLQENGFVDKYDIATVKVVNKKNE.SLT.DKKYYALRINHFDNDSFHFGKGITY.QSDFQKKLg......tcFtI..YPDMKLKDSSi......................................
G2Z5Q2_FLABF/39-169             .....MDYKWM.....kYNPLKDAFPpk..gdlKLPDELF-FIVQKQKELLFDFM.NYHfNLFIVSDVFLKLIQEYRLDLKYEISKLKIVHKNEK.ELKcDKDYYALRVSTHDDDLFDYVEDGKK.RASGARDF.........F.L..YPNLKLKPDVq......................................
D1YPM9_9FIRM/45-151             ....f-DFPWS......WFVKGQEIP.......PMPEKVY-VCLKKARGVTFDFL.PYN.DFFIMSARFLEFIKKYGFDYDFGMSEAIIVNTKGE.LLT.NEVYYLVRIVVW-------------.--EIEDEI.........-.V..YPDLALDED-df.....................................
#=GC seq_cons                   ....h.phpW.......apspstth........phPspLYhlCsKKsttLpFDah..as.phhIlS-cFLchlpc.shsccashupltlls+Ksc..ls.cchYYhlRl.ahsp-.Fh..ct.ph.pp-hpcpl...........l..Y.chpL+-psh......................................
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