GenomeNet

Database: Pfam
Entry: Imm35
LinkDB: Imm35
Original site: Imm35 
#=GF ID   Imm35
#=GF AC   PF15567.4
#=GF DE   Immunity protein 35
#=GF PI   Imm19; Imm19_; Imm35; Imm58;
#=GF AU   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L, Finn RD
#=GF SE   [1]
#=GF GA   27.50 27.50;
#=GF TC   27.80 27.50;
#=GF NC   27.10 26.90;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   22731697
#=GF RT   Polymorphic toxin systems: comprehensive characterization of
#=GF RT   trafficking modes, processing, mechanisms of action, immunity
#=GF RT   and ecology using comparative genomics.
#=GF RA   Zhang D, de Souza RF, Anantharaman V, Iyer LM, Aravind L;
#=GF RL   Biol Direct. 2012;7:18.
#=GF DR   INTERPRO; IPR029082;
#=GF CC   A predicted immunity protein with an alpha+beta fold and a
#=GF CC   conserved tryptophan residue. Proteins containing this domain
#=GF CC   are present in bacterial polymorphic toxin systems as an
#=GF CC   immediate gene neighbour of the toxin gene, usually containing a
#=GF CC   protease domain such as Tox-PL1 and Ntox40. In some instances,
#=GF CC   it is also fused to a papain-like toxin, ADP-ribosyl
#=GF CC   glycohydrolase and a S8-like peptidase [1]. Based on these
#=GF CC   associations the domain is likely to be a protease inhibitor.
#=GF SQ   47
#=GS A0A0F4KIF2_9ACTN/224-308  AC A0A0F4KIF2.1
#=GS H0TXR5_9BRAD/4-88         AC H0TXR5.1
#=GS A8AQZ6_CITK8/4-66         AC A8AQZ6.1
#=GS A0A0M2JN63_9ACTN/5-93     AC A0A0M2JN63.1
#=GS G0G1E6_AMYMS/4-90         AC G0G1E6.1
#=GS J2K1K8_9ACTN/5-88         AC J2K1K8.1
#=GS A0A0B5DAX5_9ACTN/5-85     AC A0A0B5DAX5.1
#=GS A0A0A8ECV0_9ACTN/5-95     AC A0A0A8ECV0.1
#=GS G0G1E5_AMYMS/4-101        AC G0G1E5.1
#=GS R4LHD4_9ACTN/5-84         AC R4LHD4.1
#=GS X2H389_9NEIS/2-67         AC X2H389.1
#=GS A0A0C5FTK3_9ACTN/5-86     AC A0A0C5FTK3.1
#=GS A0A0G3BVA9_9BURK/4-82     AC A0A0G3BVA9.1
#=GS V4IUW5_9ACTN/5-94         AC V4IUW5.1
#=GS F9ZWM0_METMM/18-93        AC F9ZWM0.1
#=GS YRHB_ECOLI/5-83           AC P46857.1
#=GS A0A0N1NEG7_9ACTN/5-89     AC A0A0N1NEG7.1
#=GS A0A0M8MI52_9MICO/15-93    AC A0A0M8MI52.1
#=GS A1ZTD3_9BACT/165-245      AC A1ZTD3.1
#=GS A0A0J7ZB64_STRVR/5-86     AC A0A0J7ZB64.1
#=GS U5WQC8_MYCKA/1-62         AC U5WQC8.1
#=GS D5SPH0_PLAL2/6-105        AC D5SPH0.1
#=GS D9VBD0_9ACTN/4-101        AC D9VBD0.1
#=GS A4FIB0_SACEN/239-324      AC A4FIB0.1
#=GS A0A0F4JQ24_9ACTN/5-92     AC A0A0F4JQ24.1
#=GS B5GCQ9_STRSH/1-71         AC B5GCQ9.1
#=GS I4ANE3_FLELS/5-84         AC I4ANE3.1
#=GS R4T774_AMYOR/4-124        AC R4T774.1
#=GS A0A0M2JQ24_9ACTN/5-94     AC A0A0M2JQ24.1
#=GS A0A0M8QNX1_9ACTN/2-82     AC A0A0M8QNX1.1
#=GS C9YUD4_STRSW/5-98         AC C9YUD4.1
#=GS A0A0B5DHZ9_9ACTN/5-90     AC A0A0B5DHZ9.1
#=GS R4SZF4_AMYOR/6-105        AC R4SZF4.1
#=GS K0KBP0_SACES/233-318      AC K0KBP0.1
#=GS A0A0M8VW25_9ACTN/16-105   AC A0A0M8VW25.1
#=GS U5VPP4_9ACTN/6-88         AC U5VPP4.1
#=GS A0A0N0N2D5_9ACTN/1-66     AC A0A0N0N2D5.1
#=GS A0A0M2JQG2_9ACTN/238-322  AC A0A0M2JQG2.1
#=GS D6KBG8_9ACTN/5-89         AC D6KBG8.1
#=GS R4T4Y0_AMYOR/4-103        AC R4T4Y0.1
#=GS A0A0N0MW92_9ACTN/238-322  AC A0A0N0MW92.1
#=GS C6WKK9_ACTMD/229-315      AC C6WKK9.1
#=GS E3BP68_9VIBR/7-93         AC E3BP68.1
#=GS D9T0D3_MICAI/4-87         AC D9T0D3.1
#=GS A4FKX4_SACEN/235-320      AC A4FKX4.1
#=GS L8ESK6_STRRM/5-85         AC L8ESK6.1
#=GS A0A0B5DW85_9ACTN/5-85     AC A0A0B5DW85.1
A0A0F4KIF2_9ACTN/224-308             .................EAARHKAEEWLRRTYTQPV......E-L.VSPDAGDET.ARGWLFACQTSAALRSGDWRQAML..DSAVVVPKGPQ-EP..........FLLPNSDPWgfLAAWDR-g......................................
H0TXR5_9BRAD/4-88                    ...............dk--AAALAIAWVDILCGGEA......--R.IVREATIAK.PYGWVFFYQSKEFLDDGNPSAQLA.gNAPIIVNRTTC-EL..........RLTGTAKP-..LEYYL--teyek..................................
A8AQZ6_CITK8/4-66                    ...llssshstedlqkv-------------------......---.---------.----VFCFESMEYLETGDNASRLA.gNTPFIIDKDSG-EI..........FDLGTAWP-..LEKYLK-d......................................
A0A0M2JN63_9ACTN/5-93                .................EAAVRAVEEQLERDFQQWR......ALS.ADAVRMAVVrALVWIVSWQSEEFVRTRISKYALV.gNGPYLVDRLDGRLH.........qIGVLAAKSG..--EWEADyra....................................
G0G1E6_AMYMS/4-90                    .................EEAAARAREWLCAQPGGDR......-LR.IRPEFTARR.PDGWSFTVNAAAYLDGTDIGAGLF..PGPVVLVPDDGGEIg.......vdRPAMASTPA..EAEWRPD.......................................
J2K1K8_9ACTN/5-88                    ................a-AALKIAEELLEQETGPYD.....pELS.IDYERVREK.DGIFIAPFNSVEYLETREPLDMVP.dCWPILVDLKSGKAR..........LGTLDDRPF..---WR--es.....................................
A0A0B5DAX5_9ACTN/5-85                .................DEALQLAVAFLAQSQRDDE.....pPLA.IDAERVRES.NGFLIVPYNSVQYLASRDVRQQLL.dCWPILVDLERGD--..........---------..-------vrfgtlderhlw...........................
A0A0A8ECV0_9ACTN/5-95                .................EAAVRIVEDELDRENQRWSam.gveSIR.AIVTHVEEH.ELVWKVHVQSEEYVRTRDFTAMLV.gLGPYLVDCIDGGLH.........qIGVLSEIVG..--EWEADy......................................
G0G1E5_AMYMS/4-101                   .................AEAIAKVGQWLRAVHGPDVsg..paGLR.VDTEKVLRI.PEGWSVPYNTIAFLDEGRPEKEIF..PPPSVVVREPDGELrqah.phpggLSVPVAFPG..QENWRE-v......................................
R4LHD4_9ACTN/5-84                    qravelvtellasrssa-------------------......---.LGIAAVEEH.ELGWLVHLQSTEYSRTGDLLDQVI.gQGPWLVDRDNGGVH..........-EIPV----..-------vtyggdwarly............................
X2H389_9NEIS/2-67                    ..............niy-------------------......---.CEIVHIERF.SEGWYFCYQSRNYLDTGNFSDILA.gNAPIIVDKDTG-AV..........INTVSAYPI..-EQY---ieky...................................
A0A0C5FTK3_9ACTN/5-86                .................DEALQAAAAFLARSQRDTE.....pPLA.IDTELVRES.NGLLIVPYNSVQYLASREAREQLL.dCWPILVDLERGDV-..........---------..-------rfgtleerhlwk...........................
A0A0G3BVA9_9BURK/4-82                heargiaaqfvavnvaa---------------PPED......CYL.IVDAGVIED.QDGWYFPYQSARFIETNDISYSVV.gNCPIFVSKCGK---..........---------..-------taelrrpplh.............................
V4IUW5_9ACTN/5-94                    .................EAAVRAVEEHLGREYRQRRaa.gadTMP.MVVTGVEEH.ELVWIVSWTSEAFARTGDPRFLVL.gNGPYLVDRVDGGLH.........rVGVVSALSG..--EWEAD.......................................
F9ZWM0_METMM/18-93                   ...........phewlp----------------PDD......EIV.LVDSATIER.SWGWVFFYTSRKWSETGDIQYALA.gNAPVIVERDTAKLI..........-ETGTAYS-..-------aehyidrye..............................
YRHB_ECOLI/5-83                      .................HDAFAKANHYLDDADLP--......---.VVITLHGRF.SQGWYFCFEAREFLETGDEAARLA.gNAPFIIDKDSGEIH..........-SLGTAKP-..LEEYLQD.......................................
A0A0N1NEG7_9ACTN/5-89                ................s-EAVELAAEFVKAMYPDKV.....aSLV.MLPDKCEEH.GFGWAIRFDWKEHLETGNPVDAPF..TSVVVVPHHGEAAH..........WP-PTALPV..-A-----eymrrr.................................
A0A0M8MI52_9MICO/15-93               .....qwtrdrfnegee-------------------......---.-ADERVEKQ.PWGFTVSTQSRAFLDTGDELTMLV.gGGPYIVDGQSG-EV..........WATS-SSP-..-------vayygtdeapgwsv.........................
A1ZTD3_9BACT/165-245                 ........alaeavarq--------EGLNKSNE---......TVE.LVVSNLSSV.DSVWFVGFQSQAFLLSNKVQDMLL.gNPVYLVDKQDGKIY..........---------..-------acegsgegllndf..........................
A0A0J7ZB64_STRVR/5-86                .................DEALKLAVAFLADSQSEYE.....pPLA.IDTERVRQS.NGLLIVPYNSVQYLASRDVREQLL.dCWPILVDLERGNVR..........---------..-------fgtlderhlwr............................
U5WQC8_MYCKA/1-62                    .........maeaerlg-------------------......ELM.IVDSAIVET.EDAWHFPYEAVAFVVHGDISAALA.gNVPVKVPRDGT---..........---------..-------pityea.................................
D5SPH0_PLAL2/6-105                   .....garlqvfldlqr--------------HGPRRg...peELV.ILDEHTIER.PWGWVFFFTTRG-CRDGDLTYAVG.gNAPYMVNRDGSIR-..........-LAGTGRP-..-------iedyireyeselerqsgawelvis...............
D9VBD0_9ACTN/4-101                   .................AEAVEKVGKWLRAVHGPEVsg..pgGLR.VDHDRVLRV.PEGWSIPYNTVAFLDDGRPDKELF..PAPSVLVREPDGELrqah.phpggLSTPVAYPG..QESWRE-v......................................
A4FIB0_SACEN/239-324                 .................DTAVAKATAWLEATYGG-E......VVL.VAPAAEDEL.RRGWLFACTTETFVRTGDWRDQLL..DSALVVPKDDGEDP..........FGLPNEDPWgyLRHWDAH.......................................
A0A0F4JQ24_9ACTN/5-92                ................e-RAIELVESYLAVREWPWD.....gPVPeVAVYAVEEH.SVGWLAFWDTAAFARTRDARSSFGggGSHVLVDREDGSLH..........-FVPNARDL..DEGWED-h......................................
B5GCQ9_STRSH/1-71                    ...............md-------------------......AMR.LAVVDVEEH.ELVWIVSWTSEEFGRTRNPEFMPA.gNGPYLVDRVDGGLH.........rVGVVSAVTG..--EWEADyra....................................
I4ANE3_FLELS/5-84                    .................KEAKKIAKLFLNRIDTGTR......NDK.CIITDNIEY.DFGWIFFYQSSIYLETNDPLYMLA.gNIPIIVDRVTKNIL..........F--------..-------tgseydisy..............................
R4T774_AMYOR/4-124                   .................EEAVSRVEEWLTDRGGEGT.....gALR.VRRDYVVRA.TDGWNVTYNTVGWLDGTDPGAGLF..PSPVAFVPDDGGEIrldl..elmaVSAA-----..-------gddpdaftrwaevvdpefdpaavpglpvpkaailrweqh
A0A0M2JQ24_9ACTN/5-94                ................l-DAVESATTLLRRVYPEKA.....dSIV.LFPEKSVDH.PYGWLISFDFAQHIETGDWLQSPV..TTVVVVPHDGGKAHf.......ppSIIPVAD--..-------ymnrrasgew.............................
A0A0M8QNX1_9ACTN/2-82                .....ergyqrelsagl------------------D......PMR.MAVAQVEQH.ELVWIVSWTSEEYLRTRNPSSLLI.gNGPYLVDRLDGSLH.........rVGVVSAATG..--AWEADyr.....................................
C9YUD4_STRSW/5-98                    .................EAAVRLVEEQLTRDYRTWLat.dpdAMR.MAVVRVREH.ELVWIVSWQSEEFVRTRRPERMLV.gNGPYLVDRVDGSLH.........qVGVVSAKSG..--AWEADyrar...................................
A0A0B5DHZ9_9ACTN/5-90                ................e-RAVQLVEELLSKEQQGSP......WLPeVAVHHVKKH.AFGWLFVCQSVEYVRSGDPAHLLV.gSGPYLVDGQDGSIH..........-HIPVTTYH..HEDWEQ-l......................................
R4SZF4_AMYOR/6-105                   ................g-EAIAKVQAWLRFGTPVDLtt.gehAVR.IEHERVREV.PDGWLVPYNTIRALDGGDRLASLV..PRPVLLVRENGELRrpdpepgglgPSVPVSFAG..QEDWRE-i......................................
K0KBP0_SACES/233-318                 .................DDAVRKARRHLADVYG-GQ......VVL.VDPDPADEL.DRGWLFACTTRAFLDSGDPRDQML..DAALVVPKDGRRAP..........FGLPNSDPWpwLERWDA-g......................................
A0A0M8VW25_9ACTN/16-105              .................ETAVQAVEEQLERDYQEWRav.sgdAMR.MAVVRVREH.ELVWIVSWQSEEFIRSRNREFMLV.gSGPYLVDRVDGGLH.........sIGVLSSQTG..--EWEAD.......................................
U5VPP4_9ACTN/6-88                    .................AEARDRAADKLRELQDPAT......PLR.LSDDPPDEY.AWCWVFGFNTERWFRTGELTDGAV..SGPVVVDKDGG-AV..........WIAPSAPP-..LERWLN-v......................................
A0A0N0N2D5_9ACTN/1-66                .................-------------------......---.MAVVHVEQH.ELVWIISWQSEEFVRTRNSDFMLA.gNGPYLVDRIDGGLH.........qIGVVSALTG..--EWEADyra....................................
A0A0M2JQG2_9ACTN/238-322             ................a-SAVAKARHWLDDAYKGQV......D-L.DRPTAQDET.LRAWVFSCNSRRFLGDGNWQHAML..DATVVVPKDDS-AP..........FGLPNTAPWawLARWDA-g......................................
D6KBG8_9ACTN/5-89                    .................DEAVAAAAHHLKTEAYPDRa....aSVV.MLPDTAIEF.TYGWSVCFDFKEHIETGDLAQAPF..SAVVVVPHDGTPAH..........---------..-------ipptylsvarymdm.........................
R4T4Y0_AMYOR/4-103                   .................AEAVAKVEEWLRAVHGPDVsepggaGLR.VNHEKVLRI.PEGWSVPYNTIAFLDEGHAEKEIF..PPPSVIVREPDGELrqah.pqpggLSVPVAFPG..QEAWRE-v......................................
A0A0N0MW92_9ACTN/238-322             ................s-SALRKAQLWLDQAYHGEA......E-L.VDPAPQDEI.RRGWVFACNTKRHLRDGRWQDAML..DATLVVPREAT-AP..........FGLPNSDPWtwLQRWDA-g......................................
C6WKK9_ACTMD/229-315                 .................EAAVRRAEEHLAQAYGAGE......VVL.VDPSPEDEL.SRGWLFACTTVAYRDSDDLRYQML..DAALVVPKESDRAP..........FALPNADPWpwLERWDA-g......................................
E3BP68_9VIBR/7-93                    ................n-DAHTLAEEFISKLGL-DE......ELV.VLDDETLTE.DFGWVFFYNTKKFQETGDFRDMVG.gNAPIIIDKESGRLT..........-V-------..-------tgtahevnhyieeyran......................
D9T0D3_MICAI/4-87                    .................DDARTRAQTALRRLENPEQ......PLTlLAPDAPAEY.EWCWVYPFNTVRATETGDIMDTLA..VGPLVVPKNGA-EP..........WVAPSGPP-..LERWLN-e......................................
A4FKX4_SACEN/235-320                 ................a-SALAKARSWLDQAYS-DD......VVL.VAPGPADET.RRGWLFACTTARFLGSGHWQDQML..DAALVVPKAAGEEP..........FGLPNSDPWdyLAKWDA-g......................................
L8ESK6_STRRM/5-85                    ...............ef--AMRTVQEILDHENPG--......--R.LLVTGAEEH.ELVWIVSFQSAEFVRSGDYRDFFV.gHGPYVVDRVDGSVH..........-AVGSAAAL..NREWEH-d......................................
A0A0B5DW85_9ACTN/5-85                .................DEALQLAVAFLAQSQRDDE.....pPLA.IDAEQVRES.NGFLIVPYNSVQYLASRDVRQQLL.dCWPILVDLERGD--..........---------..-------vrfgtlderhlw...........................
#=GC seq_cons                        ..................tAhthstthLtt..t.........slh.lssstspEp.shuWlhsasotpalcos-hpptlh.ssuPhlVs+csGthh..........hshssu.s......a...h......................................
//
DBGET integrated database retrieval system