GenomeNet

Database: Pfam
Entry: Imm6
LinkDB: Imm6
Original site: Imm6 
#=GF ID   Imm6
#=GF AC   PF14434.4
#=GF DE   Immunity protein Imm6
#=GF AU   Iyer LM, Zhang D, Aravind L
#=GF SE   Manual
#=GF GA   25.00 25.00;
#=GF TC   31.60 31.50;
#=GF NC   23.60 20.00;
#=GF BM   hmmbuild HMM.ann SEED.ann
#=GF SM   hmmsearch -Z 17690987 -E 1000 --cpu 4 HMM pfamseq
#=GF TP   Family
#=GF RN   [1]
#=GF RM   21890906
#=GF RT   Evolution of the deaminase fold and multiple origins of
#=GF RT   eukaryotic editing and mutagenic nucleic acid deaminases from
#=GF RT   bacterial toxin systems.
#=GF RA   Iyer LM, Zhang D, Rogozin IB, Aravind L;
#=GF RL   Nucleic Acids Res. 2011; [Epub ahead of print]
#=GF DR   INTERPRO; IPR025674;
#=GF CC   A predicted immunity protein, with an alpha+beta fold (mostly
#=GF CC   alpha  helices). The protein is present in polymorphic toxin
#=GF CC   systems as an  immediate gene neighbor of the toxin gene [1].
#=GF SQ   21
#=GS E6UJ22_RUMA7/4-116       AC E6UJ22.1
#=GS I8UAB0_9BACI/12-132      AC I8UAB0.1
#=GS U5RYF7_9CLOT/120-253     AC U5RYF7.1
#=GS W0A6E2_9SPHN/18-133      AC W0A6E2.1
#=GS Q65H88_BACLD/13-133      AC Q65H88.1
#=GS E9SC56_RUMAL/3-105       AC E9SC56.1
#=GS Q65H86_BACLD/12-132      AC Q65H86.1
#=GS D4IYW9_BUTFI/10-128      AC D4IYW9.1
#=GS D0BL33_9LACT/5-123       AC D0BL33.1
#=GS Q97M62_CLOAB/12-132      AC Q97M62.1
#=GS A0A024QIV9_9BACI/1-52    AC A0A024QIV9.1
#=GS E3H4C7_ROTDC/5-124       AC E3H4C7.1
#=GS A0A0H4KIW7_9BACI/12-132  AC A0A0H4KIW7.1
#=GS F2AFB8_RHIET/14-131      AC F2AFB8.1
#=GS A8FFG3_BACP2/11-131      AC A8FFG3.1
#=GS H7EH39_9SPIO/117-235     AC H7EH39.1
#=GS A0A0H4KRP3_9BACI/11-131  AC A0A0H4KRP3.1
#=GS Q97M61_CLOAB/12-131      AC Q97M61.1
#=GS A0A090IWW5_9BACI/1-54    AC A0A090IWW5.1
#=GS H6NMS5_9BACL/8-137       AC H6NMS5.1
#=GS A3DGZ3_CLOTH/11-132      AC A3DGZ3.1
E6UJ22_RUMA7/4-116                  ......................n-ALDYLLWITNSHKNIIG-----..........AEFADHCLSIIEK-LKS.RNYTADELYSLV--.TDDE..LLYNYTD.NAAETECEAFSQAFISVLMCMICAKYHSEGQKF..LPEDIEPIQGDKL.DGFFTYLKE-k...................
I8UAB0_9BACI/12-132                 ......................r-QVAFMLGLSETVVDLLISSSA-..........YKDINNAMKACWEWIEN.KRYSGDEIYYLLDDgTEFT..GLFMQMQ.DENEPLKELVWGCIVDAISFTNWRAYEFDNEEY..LPAPIENVDESIL.QQFLEGFY--ei..................
U5RYF7_9CLOT/120-253                ......................e-LGSILVRIGEMLLEEIKQKKNEasklsddslwVEVVERTLKVCKEFVQG.EGVTVDEIYPLLDS.EDCS..DIVEFSC.QVEDNNVILLIGHISNITSYILTLAIYKEYGEHcpLPEILDSFQGEDMpEMFIKFLLYM....................
W0A6E2_9SPHN/18-133                 ..............rrahlaldg---------GEEGLKGLSDSAQ-..........IAQARSALDLARRMLAG.E-APAYEVEDRLQN.EEDE..GILIREQ.ETGDETEKAAWLSVASAIAYAARVGYQRAGELP..-------------.----------gplvsevrddavasledhlq
Q65H88_BACLD/13-133                 ......................v-KVGFVLTVAERVFSVISKDDER..........HPEGREALDKCWLWVES.HAVTGDDLYELIDN.ADFT..GISEFAE.EEEDSNIARLWSLLVDAVAYTSWEAYKKEKVKH..LPQALEGINKDSI.TIFLNSTVE-t...................
E9SC56_RUMAL/3-105                  salayvrwlteshrsvigidkae-----------------------..........-----------------.---HLDKLFNTIEE.SDKTanAIYDLMG.TECSSDDSPFENAVISVLSCVVCKMYVEESQKY..LPEDIENIQIDKI.DSFFGYLTE-f...................
Q65H86_BACLD/12-132                 ......................l-KSAYYLGLCEAIVPTLKQSND-..........FNFIKEALDACWKWLEH.KNIEADDLYTYLEN.LDDT..GILTLMQ.LESNEDDLDAWICIADAISYTIYKAYKYQKDEY..LPETIESIDSYELfEEFHSHF---sll.................
D4IYW9_BUTFI/10-128                 ......................n-IYKFAIAIAEKASSYIDDSET-..........VEIINESLEVCKKWTQE.GGNVGESLYDYLDN.-EEN..GFTIFQE.MEESERVINAWDCIIDAIAYISKAAYEKEGVEY..LPEPIELVDDSIL.SHMIQALIL-c...................
D0BL33_9LACT/5-123                  ....................nal----FKLGIATWLSKSMQESQF-..........YNKIEELLEECWKWVEN.HEVSADVLYSLLDDgTDFG..GAFIYMQ.-VDEPKYESEWNCIFEAGASIASLAYKLEGKKY..IPALLEEIDSAQQ.EEFYSEQLE-n...................
Q97M62_CLOAB/12-132                 ......................a-KVTIGLVIAEKVFSLIDKNDYG..........YNLGREALDNSWKWLEG.EEIDADELCDYIGNiDGEE..DISGIAY.ITKQIKYKHMWYVLYYAIAYTSWLAYINEDSCP..-PEELDNVSDDTL.IYIIQNAIK-t...................
A0A024QIV9_9BACI/1-52               .....................ms-----------------------..........-----------------.--------------.----..-------.------IARIWSLLVDAVAYTSWEAYKNEEVKY..LPQSLESITTDSI.ITFLNSAVE-t...................
E3H4C7_ROTDC/5-124                  ......................k-LANFMQILTECLPSYLKKKED-..........IVFVKKTLEMTQDFLLDkETVSPDALYDRLEN.INEE..DILTYFD.-LDKESAPSVWVCIADFVAYICKLSYDESGEKY..LPETIEAVDEATL.TEFFTQYKE-n...................
A0A0H4KIW7_9BACI/12-132             .....................sq--VACLVLLSEKVVDRLRGTEG-..........YPEAKRALRRCADWSKV.QREKGDNLYSLLEDgSDES..GLFNYTGyIDMEEETEQVWDCVVSTVAYTAYWAYAYEGQKY..VPQTLESIDEELI.EHFLA-----gfya................
F2AFB8_RHIET/14-131                 ..................eqarr-----LATVAACLVVQIAKSEID..........APEAEAALAAIRGWGDG.ADLTGRYFSDLIYS.EDER..GTLRRLC.EAAGKPSEGGWNALTTTTIYVAWLVYQ-ETGEP..MPSDVNEVGGDSL.DLL-------daqla...............
A8FFG3_BACP2/11-131                 ......................a-KVALGLAIAEKMYVFIDKEDDG..........YHVGEKALEDCWKWLSG.KELSADDLCNYIDS.EDYM..DVAEFAN.KQKDEQKQYGWYSVLDAVSYTAYQAYRRENKKF..VPQVLEVIDDETL.IVMWENAIE-s...................
H7EH39_9SPIO/117-235                ......................n-KCVFAIKLAERASRYIVDTEK-..........LTLINNAIEIALTFVQT.EKGNGEVLYNFLDN.-ENN..GFTIFQE.MEIDEKIRDAWDCIIDAIAYITKEIYLVNGEKY..FPEPIEMVDDTIF.THMINALKL-c...................
A0A0H4KRP3_9BACI/11-131             ......................s-KVATGLIIAEKLFYIIKSNEPG..........YQTGRGALDDCWKWLTG.ENVTGDDLYNYIDS.GDYI..DITEFAN.DEEDRSKQHAWYAVLDAVSYTIYQAYQKENVKI..VPQAMESINDDAL.KTLGENAIE-s...................
Q97M61_CLOAB/12-131                 ......................g-KAAVALIMSEITLNSIEQHNTE..........YKFCRDAIDMCWEWLEG.GNVNKYEICSLIAN.-DNK..CLADITS.NTEDDKLGNKYGTIMISVSYVAWQAYNKENNYH..YPQYLEIIDDEYL.VELIKDLIE-i...................
A0A090IWW5_9BACI/1-54               ......................m-----------------------..........--------------LNS.EENIGDILYELLDN.-EEN..GITIIQE.MSDNETDVEAWNCIIDAVAYTSR----------..-------------.----------lvi.................
H6NMS5_9BACL/8-137                  ......................s-KVAISLAYAERTLDYLENEIRDrky....dqaFEKFRMIIRKGHEWLAG.NHVDWDEVYRMCNDdEEEY..GCFDFIAnAEVTERYETASIVLIWSIYYFMYQCAHRSNERY..FPQDL--------.----------wdghlpeeeetkmlnslhc.
A3DGZ3_CLOTH/11-132                 ......................a-RVAFYLAVAQKAFEGLSENDQG..........YLQADEALKQCWNWLKG.KNISGDELCEYLEN.ERDT..GLMVYSSfVQGDPVKEPIWITIITALMYTIWQAYQIENEKY..LPESIEQVDEGTI.DILIEYAKKC....................
#=GC seq_cons                       ......................t.hsshhlhluEphhphlppppt...........ht.hcpuLchshcWlps.cphsuDcLYshl-s.t-pp..ulhthtp..ppcpphpphWssllsAluYsshtAYppEspca..lPpslEtlspstl.p.hhp.hh..s...................
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